1128398:CURI RS08405
gene id: 1128398:CURI_RS08405
uniprot id: K0B0T1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1128398:CURI RS13955
gene id: 1128398:CURI_RS13955
uniprot id: K0B4C3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS00930
gene id: 1128398:CURI_RS00930
uniprot id: K0AWW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1128398:CURI RS12925
gene id: 1128398:CURI_RS12925
uniprot id: K0B3V0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1128398:CURI RS09335
gene id: 1128398:CURI_RS09335
uniprot id: K0B1C5
names: Similarity
messages: Belongs to the GerABKA family.

1128398:CURI RS04795
gene id: 1128398:CURI_RS04795
uniprot id: K0AVT0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1128398:CURI RS00510
gene id: 1128398:CURI_RS00510
uniprot id: K0AV89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1128398:CURI RS12360
gene id: 1128398:CURI_RS12360
uniprot id: K0B0A7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1128398:CURI RS01280
gene id: 1128398:CURI_RS01280
uniprot id: K0AX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1128398:CURI RS08775
gene id: 1128398:CURI_RS08775
uniprot id: K0B297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1128398:CURI RS06400
gene id: 1128398:CURI_RS06400
uniprot id: K0AYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1128398:CURI RS08455
gene id: 1128398:CURI_RS08455
uniprot id: K0B0U1
names: Similarity
messages: Belongs to the RemA family.

1128398:CURI RS05770
gene id: 1128398:CURI_RS05770
uniprot id: K0AZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1128398:CURI RS07075
gene id: 1128398:CURI_RS07075
uniprot id: K0B1A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1128398:CURI RS03685
gene id: 1128398:CURI_RS03685
uniprot id: K0AZK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1128398:CURI RS13245
gene id: 1128398:CURI_RS13245
uniprot id: K0B3Z6
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS00155
gene id: 1128398:CURI_RS00155
uniprot id: K0ATC0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS03000
gene id: 1128398:CURI_RS03000
uniprot id: K0AWQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1128398:CURI RS09030
gene id: 1128398:CURI_RS09030
uniprot id: K0B163
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1128398:CURI RS04155
gene id: 1128398:CURI_RS04155
uniprot id: K0AYZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1128398:CURI RS10780
gene id: 1128398:CURI_RS10780
uniprot id: K0B0W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS10500
gene id: 1128398:CURI_RS10500
uniprot id: K0B385
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1128398:CURI RS14285
gene id: 1128398:CURI_RS14285
uniprot id: K0B305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1128398:CURI RS08545
gene id: 1128398:CURI_RS08545
uniprot id: K0AZL6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS01630
gene id: 1128398:CURI_RS01630
uniprot id: K0AYF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1128398:CURI RS15045
gene id: 1128398:CURI_RS15045
uniprot id: K0B0Z8
names: Similarity
messages: Belongs to the FlgD family.

1128398:CURI RS05265
gene id: 1128398:CURI_RS05265
uniprot id: K0AZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS08435
gene id: 1128398:CURI_RS08435
uniprot id: K0AY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1128398:CURI RS04845
gene id: 1128398:CURI_RS04845
uniprot id: K0AXS0
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS05780
gene id: 1128398:CURI_RS05780
uniprot id: K0AZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1128398:CURI RS10915
gene id: 1128398:CURI_RS10915
uniprot id: K0B3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1128398:CURI RS09130
gene id: 1128398:CURI_RS09130
uniprot id: K0B2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1128398:CURI RS10835
gene id: 1128398:CURI_RS10835
uniprot id: K0B2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00100
gene id: 1128398:CURI_RS00100
uniprot id: K0AWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1128398:CURI RS10540
gene id: 1128398:CURI_RS10540
uniprot id: K0B0Q8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1128398:CURI RS12810
gene id: 1128398:CURI_RS12810
uniprot id: K0B0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1128398:CURI RS00335
gene id: 1128398:CURI_RS00335
uniprot id: K0AWP1
names: Similarity
messages: Belongs to the threonine synthase family.

1128398:CURI RS12755
gene id: 1128398:CURI_RS12755
uniprot id: K0B2Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06550
gene id: 1128398:CURI_RS06550
uniprot id: K0B015
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1128398:CURI RS11430
gene id: 1128398:CURI_RS11430
uniprot id: K0B2F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1128398:CURI RS08820
gene id: 1128398:CURI_RS08820
uniprot id: K0B1D0
names: Similarity
messages: Belongs to the UPF0473 family.

1128398:CURI RS08845
gene id: 1128398:CURI_RS08845
uniprot id: K0B1D4
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS06450
gene id: 1128398:CURI_RS06450
uniprot id: K0AYF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS12220
gene id: 1128398:CURI_RS12220
uniprot id: K0B1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS14015
gene id: 1128398:CURI_RS14015
uniprot id: K0B3T2
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS00735
gene id: 1128398:CURI_RS00735
uniprot id: K0AVC7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1128398:CURI RS10950
gene id: 1128398:CURI_RS10950
uniprot id: K0AZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00040
gene id: 1128398:CURI_RS00040
uniprot id: K0AT96
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1128398:CURI RS13135
gene id: 1128398:CURI_RS13135
uniprot id: K0B370
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1128398:CURI RS03230
gene id: 1128398:CURI_RS03230
uniprot id: K0AV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1128398:CURI RS11830
gene id: 1128398:CURI_RS11830
uniprot id: K0B489
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1128398:CURI RS12050
gene id: 1128398:CURI_RS12050
uniprot id: K0B3I6
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS14290
gene id: 1128398:CURI_RS14290
uniprot id: K0B4K0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1128398:CURI RS14685
gene id: 1128398:CURI_RS14685
uniprot id: K0B619
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1128398:CURI RS11325
gene id: 1128398:CURI_RS11325
uniprot id: K0B3W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1128398:CURI RS08940
gene id: 1128398:CURI_RS08940
uniprot id: K0AYD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS04075
gene id: 1128398:CURI_RS04075
uniprot id: K0AYV9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS11765
gene id: 1128398:CURI_RS11765
uniprot id: K0B2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS08140
gene id: 1128398:CURI_RS08140
uniprot id: K0AZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1128398:CURI RS05975
gene id: 1128398:CURI_RS05975
uniprot id: K0AY74
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1128398:CURI RS13645
gene id: 1128398:CURI_RS13645
uniprot id: K0B457
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS01840
gene id: 1128398:CURI_RS01840
uniprot id: K0AUD3
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1128398:CURI RS05090
gene id: 1128398:CURI_RS05090
uniprot id: K0AZ05
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1128398:CURI RS12460
gene id: 1128398:CURI_RS12460
uniprot id: K0B1Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1128398:CURI RS00010
gene id: 1128398:CURI_RS00010
uniprot id: K0AWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1128398:CURI RS14740
gene id: 1128398:CURI_RS14740
uniprot id: K0B624
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1128398:CURI RS13420
gene id: 1128398:CURI_RS13420
uniprot id: K0B2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1128398:CURI RS09055
gene id: 1128398:CURI_RS09055
uniprot id: K0B168
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS11630
gene id: 1128398:CURI_RS11630
uniprot id: K0B2J3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS10700
gene id: 1128398:CURI_RS10700
uniprot id: K0AZB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS09975
gene id: 1128398:CURI_RS09975
uniprot id: K0B248
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1128398:CURI RS14860
gene id: 1128398:CURI_RS14860
uniprot id: K0AX12
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1128398:CURI RS13160
gene id: 1128398:CURI_RS13160
uniprot id: K0B373
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1128398:CURI RS16405
gene id: 1128398:CURI_RS16405
uniprot id: K0B241
names: Subunit
messages: Homodimer.

1128398:CURI RS13890
gene id: 1128398:CURI_RS13890
uniprot id: K0B180
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS06525
gene id: 1128398:CURI_RS06525
uniprot id: K0B009
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1128398:CURI RS01390
gene id: 1128398:CURI_RS01390
uniprot id: K0AVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS11240
gene id: 1128398:CURI_RS11240
uniprot id: K0B162
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1128398:CURI RS10105
gene id: 1128398:CURI_RS10105
uniprot id: K0B312
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1128398:CURI RS00485
gene id: 1128398:CURI_RS00485
uniprot id: K0AV85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1128398:CURI RS14605
gene id: 1128398:CURI_RS14605
uniprot id: K0B4S9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS03055
gene id: 1128398:CURI_RS03055
uniprot id: K0AY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS07280
gene id: 1128398:CURI_RS07280
uniprot id: K0B091
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1128398:CURI RS11190
gene id: 1128398:CURI_RS11190
uniprot id: K0B2S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1128398:CURI RS05515
gene id: 1128398:CURI_RS05515
uniprot id: K0AZG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1128398:CURI RS07105
gene id: 1128398:CURI_RS07105
uniprot id: K0B1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1128398:CURI RS00005
gene id: 1128398:CURI_RS00005
uniprot id: K0AXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1128398:CURI RS11290
gene id: 1128398:CURI_RS11290
uniprot id: K0B173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1128398:CURI RS11990
gene id: 1128398:CURI_RS11990
uniprot id: K0B041
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1128398:CURI RS11310
gene id: 1128398:CURI_RS11310
uniprot id: K0AZN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1128398:CURI RS09890
gene id: 1128398:CURI_RS09890
uniprot id: K0AYW0
names: Similarity
messages: Belongs to the RutC family.

1128398:CURI RS12975
gene id: 1128398:CURI_RS12975
uniprot id: K0B3V7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1128398:CURI RS02550
gene id: 1128398:CURI_RS02550
uniprot id: K0AUM4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1128398:CURI RS09410
gene id: 1128398:CURI_RS09410
uniprot id: K0B2R7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1128398:CURI RS03290
gene id: 1128398:CURI_RS03290
uniprot id: K0AY89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS05700
gene id: 1128398:CURI_RS05700
uniprot id: K0B0G4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1128398:CURI RS08145
gene id: 1128398:CURI_RS08145
uniprot id: K0B120
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1128398:CURI RS08850
gene id: 1128398:CURI_RS08850
uniprot id: K0B2B7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1128398:CURI RS06205
gene id: 1128398:CURI_RS06205
uniprot id: K0AWN3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1128398:CURI RS11745
gene id: 1128398:CURI_RS11745
uniprot id: K0B1I5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1128398:CURI RS11140
gene id: 1128398:CURI_RS11140
uniprot id: K0B2R3
names: Similarity
messages: Belongs to the universal stress protein A family.

1128398:CURI RS05740
gene id: 1128398:CURI_RS05740
uniprot id: K0AY41
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1128398:CURI RS03935
gene id: 1128398:CURI_RS03935
uniprot id: K0AYP5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS09145
gene id: 1128398:CURI_RS09145
uniprot id: K0AZX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1128398:CURI RS02470
gene id: 1128398:CURI_RS02470
uniprot id: K0AXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS11390
gene id: 1128398:CURI_RS11390
uniprot id: K0B197
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1128398:CURI RS12055
gene id: 1128398:CURI_RS12055
uniprot id: K0B4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1128398:CURI RS05335
gene id: 1128398:CURI_RS05335
uniprot id: K0AZD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1128398:CURI RS11940
gene id: 1128398:CURI_RS11940
uniprot id: K0B021
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1128398:CURI RS03945
gene id: 1128398:CURI_RS03945
uniprot id: K0AYK7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS07000
gene id: 1128398:CURI_RS07000
uniprot id: K0B0I1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1128398:CURI RS08170
gene id: 1128398:CURI_RS08170
uniprot id: K0B122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1128398:CURI RS08515
gene id: 1128398:CURI_RS08515
uniprot id: K0AZL1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1128398:CURI RS01990
gene id: 1128398:CURI_RS01990
uniprot id: K0AUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS07980
gene id: 1128398:CURI_RS07980
uniprot id: K0AXR1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1128398:CURI RS00770
gene id: 1128398:CURI_RS00770
uniprot id: K0AWW9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1128398:CURI RS11110
gene id: 1128398:CURI_RS11110
uniprot id: K0B135
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1128398:CURI RS00475
gene id: 1128398:CURI_RS00475
uniprot id: K0ATJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1128398:CURI RS09255
gene id: 1128398:CURI_RS09255
uniprot id: K0B1N2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1128398:CURI RS07670
gene id: 1128398:CURI_RS07670
uniprot id: K0B0F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1128398:CURI RS00020
gene id: 1128398:CURI_RS00020
uniprot id: K0AV03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1128398:CURI RS13010
gene id: 1128398:CURI_RS13010
uniprot id: K0B342
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS01100
gene id: 1128398:CURI_RS01100
uniprot id: K0AY29
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1128398:CURI RS10645
gene id: 1128398:CURI_RS10645
uniprot id: K0B2G9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS08035
gene id: 1128398:CURI_RS08035
uniprot id: K0AZB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1128398:CURI RS10065
gene id: 1128398:CURI_RS10065
uniprot id: K0AYY4
names: Similarity
messages: Belongs to the peptidase S11 family.

1128398:CURI RS09270
gene id: 1128398:CURI_RS09270
uniprot id: K0B001
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1128398:CURI RS04025
gene id: 1128398:CURI_RS04025
uniprot id: K0AYT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS09765
gene id: 1128398:CURI_RS09765
uniprot id: K0B2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS12280
gene id: 1128398:CURI_RS12280
uniprot id: K0B4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1128398:CURI RS14490
gene id: 1128398:CURI_RS14490
uniprot id: K0B1K4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1128398:CURI RS08570
gene id: 1128398:CURI_RS08570
uniprot id: K0AZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1128398:CURI RS05330
gene id: 1128398:CURI_RS05330
uniprot id: K0AXY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1128398:CURI RS10545
gene id: 1128398:CURI_RS10545
uniprot id: K0B2F1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1128398:CURI RS00690
gene id: 1128398:CURI_RS00690
uniprot id: K0AWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1128398:CURI RS01675
gene id: 1128398:CURI_RS01675
uniprot id: K0AYG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1128398:CURI RS08810
gene id: 1128398:CURI_RS08810
uniprot id: K0AYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1128398:CURI RS11035
gene id: 1128398:CURI_RS11035
uniprot id: K0B119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

1128398:CURI RS05050
gene id: 1128398:CURI_RS05050
uniprot id: K0AXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS13275
gene id: 1128398:CURI_RS13275
uniprot id: K0B511
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1128398:CURI RS12960
gene id: 1128398:CURI_RS12960
uniprot id: K0B329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1128398:CURI RS06065
gene id: 1128398:CURI_RS06065
uniprot id: K0AZK2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1128398:CURI RS13600
gene id: 1128398:CURI_RS13600
uniprot id: K0B598
names: Similarity
messages: Belongs to the Lgt family.

1128398:CURI RS11150
gene id: 1128398:CURI_RS11150
uniprot id: K0B290
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1128398:CURI RS15990
gene id: 1128398:CURI_RS15990
uniprot id: K0AVF5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1128398:CURI RS03590
gene id: 1128398:CURI_RS03590
uniprot id: K0AZI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS13430
gene id: 1128398:CURI_RS13430
uniprot id: K0B553
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1128398:CURI RS06545
gene id: 1128398:CURI_RS06545
uniprot id: K0AYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1128398:CURI RS07800
gene id: 1128398:CURI_RS07800
uniprot id: K0AXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1128398:CURI RS05405
gene id: 1128398:CURI_RS05405
uniprot id: K0AW23
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1128398:CURI RS09060
gene id: 1128398:CURI_RS09060
uniprot id: K0AYG3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1128398:CURI RS05490
gene id: 1128398:CURI_RS05490
uniprot id: K0AZG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS03150
gene id: 1128398:CURI_RS03150
uniprot id: K0AV01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1128398:CURI RS01350
gene id: 1128398:CURI_RS01350
uniprot id: K0AY96
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1128398:CURI RS05425
gene id: 1128398:CURI_RS05425
uniprot id: K0AZ67
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS05390
gene id: 1128398:CURI_RS05390
uniprot id: K0B0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1128398:CURI RS04285
gene id: 1128398:CURI_RS04285
uniprot id: K0AXN0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1128398:CURI RS03025
gene id: 1128398:CURI_RS03025
uniprot id: K0AWR2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1128398:CURI RS10465
gene id: 1128398:CURI_RS10465
uniprot id: K0B0N9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06575
gene id: 1128398:CURI_RS06575
uniprot id: K0B020
names: Similarity
messages: Belongs to the UPF0749 family.

1128398:CURI RS11195
gene id: 1128398:CURI_RS11195
uniprot id: K0B3S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1128398:CURI RS06955
gene id: 1128398:CURI_RS06955
uniprot id: K0B190
names: Similarity
messages: Belongs to the asp23 family.

1128398:CURI RS14765
gene id: 1128398:CURI_RS14765
uniprot id: K0B628
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1128398:CURI RS14665
gene id: 1128398:CURI_RS14665
uniprot id: K0B463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS03680
gene id: 1128398:CURI_RS03680
uniprot id: K0AYH8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS08125
gene id: 1128398:CURI_RS08125
uniprot id: K0B1Q5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1128398:CURI RS09545
gene id: 1128398:CURI_RS09545
uniprot id: K0AYR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1128398:CURI RS04775
gene id: 1128398:CURI_RS04775
uniprot id: K0AXQ8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS03425
gene id: 1128398:CURI_RS03425
uniprot id: K0AV60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1128398:CURI RS14450
gene id: 1128398:CURI_RS14450
uniprot id: K0B1J7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1128398:CURI RS10560
gene id: 1128398:CURI_RS10560
uniprot id: K0AZ86
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS13590
gene id: 1128398:CURI_RS13590
uniprot id: K0B2I9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS05510
gene id: 1128398:CURI_RS05510
uniprot id: K0AY14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1128398:CURI RS05965
gene id: 1128398:CURI_RS05965
uniprot id: K0AZI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1128398:CURI RS03710
gene id: 1128398:CURI_RS03710
uniprot id: K0AYI6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1128398:CURI RS10370
gene id: 1128398:CURI_RS10370
uniprot id: K0B2B8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1128398:CURI RS11155
gene id: 1128398:CURI_RS11155
uniprot id: K0AZK6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS11405
gene id: 1128398:CURI_RS11405
uniprot id: K0AZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1128398:CURI RS08660
gene id: 1128398:CURI_RS08660
uniprot id: K0B0Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS14260
gene id: 1128398:CURI_RS14260
uniprot id: K0B4J2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1128398:CURI RS06015
gene id: 1128398:CURI_RS06015
uniprot id: K0AZJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS14040
gene id: 1128398:CURI_RS14040
uniprot id: K0B3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1128398:CURI RS12930
gene id: 1128398:CURI_RS12930
uniprot id: K0B4S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1128398:CURI RS06985
gene id: 1128398:CURI_RS06985
uniprot id: K0B043
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1128398:CURI RS14150
gene id: 1128398:CURI_RS14150
uniprot id: K0B3W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS12040
gene id: 1128398:CURI_RS12040
uniprot id: K0B046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1128398:CURI RS05075
gene id: 1128398:CURI_RS05075
uniprot id: K0AXV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1128398:CURI RS05040
gene id: 1128398:CURI_RS05040
uniprot id: K0AYZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS06480
gene id: 1128398:CURI_RS06480
uniprot id: K0AZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1128398:CURI RS00375
gene id: 1128398:CURI_RS00375
uniprot id: K0ATH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1128398:CURI RS00965
gene id: 1128398:CURI_RS00965
uniprot id: K0AVG4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1128398:CURI RS08780
gene id: 1128398:CURI_RS08780
uniprot id: K0B112
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1128398:CURI RS04895
gene id: 1128398:CURI_RS04895
uniprot id: K0AXS7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1128398:CURI RS08365
gene id: 1128398:CURI_RS08365
uniprot id: K0AZI0
names: Similarity
messages: Belongs to the asp23 family.

1128398:CURI RS12115
gene id: 1128398:CURI_RS12115
uniprot id: K0B059
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1128398:CURI RS08190
gene id: 1128398:CURI_RS08190
uniprot id: K0AZE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1128398:CURI RS08105
gene id: 1128398:CURI_RS08105
uniprot id: K0B0M9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1128398:CURI RS14925
gene id: 1128398:CURI_RS14925
uniprot id: K0AZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1128398:CURI RS08945
gene id: 1128398:CURI_RS08945
uniprot id: K0AZU1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1128398:CURI RS12330
gene id: 1128398:CURI_RS12330
uniprot id: K0B2U3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1128398:CURI RS03410
gene id: 1128398:CURI_RS03410
uniprot id: K0AYB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS01570
gene id: 1128398:CURI_RS01570
uniprot id: K0AXF3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1128398:CURI RS12945
gene id: 1128398:CURI_RS12945
uniprot id: K0B270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS00565
gene id: 1128398:CURI_RS00565
uniprot id: P00198
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1128398:CURI RS07840
gene id: 1128398:CURI_RS07840
uniprot id: K0B0X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1128398:CURI RS06520
gene id: 1128398:CURI_RS06520
uniprot id: K0AWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1128398:CURI RS06340
gene id: 1128398:CURI_RS06340
uniprot id: K0B0U4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1128398:CURI RS11145
gene id: 1128398:CURI_RS11145
uniprot id: K0B3Q9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1128398:CURI RS11935
gene id: 1128398:CURI_RS11935
uniprot id: K0B2P2
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1128398:CURI RS01575
gene id: 1128398:CURI_RS01575
uniprot id: K0AYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00520
gene id: 1128398:CURI_RS00520
uniprot id: K0AWN8
names: Similarity
messages: Belongs to the class-I fumarase family.

1128398:CURI RS09830
gene id: 1128398:CURI_RS09830
uniprot id: K0AYV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS08095
gene id: 1128398:CURI_RS08095
uniprot id: K0B114
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1128398:CURI RS01725
gene id: 1128398:CURI_RS01725
uniprot id: K0AXH1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1128398:CURI RS14810
gene id: 1128398:CURI_RS14810
uniprot id: K0B3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS10400
gene id: 1128398:CURI_RS10400
uniprot id: K0B368
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1128398:CURI RS00895
gene id: 1128398:CURI_RS00895
uniprot id: K0AWY8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1128398:CURI RS10525
gene id: 1128398:CURI_RS10525
uniprot id: K0B390
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1128398:CURI RS00365
gene id: 1128398:CURI_RS00365
uniprot id: K0AXI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1128398:CURI RS13270
gene id: 1128398:CURI_RS13270
uniprot id: K0B3Z9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1128398:CURI RS08410
gene id: 1128398:CURI_RS08410
uniprot id: K0AY16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1128398:CURI RS13395
gene id: 1128398:CURI_RS13395
uniprot id: K0B2E9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS06565
gene id: 1128398:CURI_RS06565
uniprot id: K0AWX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS07120
gene id: 1128398:CURI_RS07120
uniprot id: K0AYV2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1128398:CURI RS10030
gene id: 1128398:CURI_RS10030
uniprot id: K0B301
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1128398:CURI RS11225
gene id: 1128398:CURI_RS11225
uniprot id: K0B3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1128398:CURI RS12665
gene id: 1128398:CURI_RS12665
uniprot id: K0B227
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1128398:CURI RS06560
gene id: 1128398:CURI_RS06560
uniprot id: K0AZV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS12595
gene id: 1128398:CURI_RS12595
uniprot id: K0B3Q8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1128398:CURI RS00030
gene id: 1128398:CURI_RS00030
uniprot id: K0AXB9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1128398:CURI RS06615
gene id: 1128398:CURI_RS06615
uniprot id: K0AWY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1128398:CURI RS11460
gene id: 1128398:CURI_RS11460
uniprot id: K0AZR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS14140
gene id: 1128398:CURI_RS14140
uniprot id: K0B4G3
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS08290
gene id: 1128398:CURI_RS08290
uniprot id: K0B142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1128398:CURI RS14720
gene id: 1128398:CURI_RS14720
uniprot id: K0B468
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1128398:CURI RS06655
gene id: 1128398:CURI_RS06655
uniprot id: K0B111
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS07845
gene id: 1128398:CURI_RS07845
uniprot id: K0B1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1128398:CURI RS03020
gene id: 1128398:CURI_RS03020
uniprot id: K0AUW9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1128398:CURI RS12315
gene id: 1128398:CURI_RS12315
uniprot id: K0B1X1
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS09210
gene id: 1128398:CURI_RS09210
uniprot id: K0B2L2
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS02575
gene id: 1128398:CURI_RS02575
uniprot id: K0AWH9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1128398:CURI RS09080
gene id: 1128398:CURI_RS09080
uniprot id: K0B174
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1128398:CURI RS03500
gene id: 1128398:CURI_RS03500
uniprot id: K0AV77
names: Similarity
messages: Belongs to the UPF0749 family.

1128398:CURI RS05545
gene id: 1128398:CURI_RS05545
uniprot id: K0AZH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1128398:CURI RS00235
gene id: 1128398:CURI_RS00235
uniprot id: K0AV37
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1128398:CURI RS10095
gene id: 1128398:CURI_RS10095
uniprot id: K0B0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1128398:CURI RS11315
gene id: 1128398:CURI_RS11315
uniprot id: K0B177
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1128398:CURI RS00760
gene id: 1128398:CURI_RS00760
uniprot id: K0ATQ4
names: Similarity
messages: Belongs to the GerABKA family.

1128398:CURI RS00855
gene id: 1128398:CURI_RS00855
uniprot id: K0AWU6
names: Similarity
messages: Belongs to the UPF0371 family.

1128398:CURI RS12080
gene id: 1128398:CURI_RS12080
uniprot id: K0B4G2
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS05095
gene id: 1128398:CURI_RS05095
uniprot id: K0AVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1128398:CURI RS10395
gene id: 1128398:CURI_RS10395
uniprot id: K0B2C3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS05730
gene id: 1128398:CURI_RS05730
uniprot id: K0AZD1
names: Similarity
messages: Belongs to the UPF0178 family.

1128398:CURI RS06725
gene id: 1128398:CURI_RS06725
uniprot id: K0B130
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1128398:CURI RS10415
gene id: 1128398:CURI_RS10415
uniprot id: K0B0M6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1128398:CURI RS08785
gene id: 1128398:CURI_RS08785
uniprot id: K0AYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1128398:CURI RS09555
gene id: 1128398:CURI_RS09555
uniprot id: K0B1X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1128398:CURI RS08310
gene id: 1128398:CURI_RS08310
uniprot id: K0AZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1128398:CURI RS11185
gene id: 1128398:CURI_RS11185
uniprot id: K0B150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1128398:CURI RS04265
gene id: 1128398:CURI_RS04265
uniprot id: K0AZY9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1128398:CURI RS03010
gene id: 1128398:CURI_RS03010
uniprot id: K0AZ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1128398:CURI RS10130
gene id: 1128398:CURI_RS10130
uniprot id: K0B314
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1128398:CURI RS06440
gene id: 1128398:CURI_RS06440
uniprot id: K0AZS6
names: Similarity
messages: Belongs to the GSP E family.

1128398:CURI RS06700
gene id: 1128398:CURI_RS06700
uniprot id: K0B121
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1128398:CURI RS04885
gene id: 1128398:CURI_RS04885
uniprot id: K0AYW6
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS04780
gene id: 1128398:CURI_RS04780
uniprot id: K0AZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1128398:CURI RS10630
gene id: 1128398:CURI_RS10630
uniprot id: K0B1Y6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS06010
gene id: 1128398:CURI_RS06010
uniprot id: K0B0N0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1128398:CURI RS05715
gene id: 1128398:CURI_RS05715
uniprot id: K0AZK0
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1128398:CURI RS08390
gene id: 1128398:CURI_RS08390
uniprot id: K0AZI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1128398:CURI RS12920
gene id: 1128398:CURI_RS12920
uniprot id: K0B265
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1128398:CURI RS11835
gene id: 1128398:CURI_RS11835
uniprot id: K0B2M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS03015
gene id: 1128398:CURI_RS03015
uniprot id: K0AY20
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1128398:CURI RS08770
gene id: 1128398:CURI_RS08770
uniprot id: K0B1B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1128398:CURI RS07710
gene id: 1128398:CURI_RS07710
uniprot id: K0B0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1128398:CURI RS06240
gene id: 1128398:CURI_RS06240
uniprot id: K0AZU4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS14970
gene id: 1128398:CURI_RS14970
uniprot id: K0AXV6
names: Similarity
messages: Belongs to the transpeptidase family.

1128398:CURI RS12455
gene id: 1128398:CURI_RS12455
uniprot id: K0B0C6
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS05500
gene id: 1128398:CURI_RS05500
uniprot id: K0AZ84
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1128398:CURI RS01295
gene id: 1128398:CURI_RS01295
uniprot id: K0AX69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1128398:CURI RS12445
gene id: 1128398:CURI_RS12445
uniprot id: K0B4K9
names: Similarity
messages: Belongs to the CobH/CbiC family.

1128398:CURI RS06175
gene id: 1128398:CURI_RS06175
uniprot id: K0AZM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1128398:CURI RS08030
gene id: 1128398:CURI_RS08030
uniprot id: K0AXS4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1128398:CURI RS01755
gene id: 1128398:CURI_RS01755
uniprot id: K0AYH2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1128398:CURI RS12275
gene id: 1128398:CURI_RS12275
uniprot id: K0B3L6
names: Similarity
messages: Belongs to the CFA/CMAS family.

1128398:CURI RS06235
gene id: 1128398:CURI_RS06235
uniprot id: K0AYB7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1128398:CURI RS06180
gene id: 1128398:CURI_RS06180
uniprot id: K0AWM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1128398:CURI RS07810
gene id: 1128398:CURI_RS07810
uniprot id: K0AZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1128398:CURI RS12085
gene id: 1128398:CURI_RS12085
uniprot id: K0B2R5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS10460
gene id: 1128398:CURI_RS10460
uniprot id: K0AZ70
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1128398:CURI RS01125
gene id: 1128398:CURI_RS01125
uniprot id: K0AY36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1128398:CURI RS09560
gene id: 1128398:CURI_RS09560
uniprot id: K0B2U2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1128398:CURI RS02485
gene id: 1128398:CURI_RS02485
uniprot id: K0AXU7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1128398:CURI RS06750
gene id: 1128398:CURI_RS06750
uniprot id: K0B136
names: Similarity
messages: Belongs to the UPF0473 family.

1128398:CURI RS04975
gene id: 1128398:CURI_RS04975
uniprot id: K0B032
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS11685
gene id: 1128398:CURI_RS11685
uniprot id: K0B1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1128398:CURI RS08580
gene id: 1128398:CURI_RS08580
uniprot id: K0B238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1128398:CURI RS10675
gene id: 1128398:CURI_RS10675
uniprot id: K0B1Z5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1128398:CURI RS11450
gene id: 1128398:CURI_RS11450
uniprot id: K0B3Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS00035
gene id: 1128398:CURI_RS00035
uniprot id: K0AWF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1128398:CURI RS00325
gene id: 1128398:CURI_RS00325
uniprot id: K0ATG2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1128398:CURI RS05550
gene id: 1128398:CURI_RS05550
uniprot id: K0B0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1128398:CURI RS00265
gene id: 1128398:CURI_RS00265
uniprot id: K0AV43
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS10265
gene id: 1128398:CURI_RS10265
uniprot id: K0AZ27
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1128398:CURI RS07685
gene id: 1128398:CURI_RS07685
uniprot id: K0B0U9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS00920
gene id: 1128398:CURI_RS00920
uniprot id: K0AWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1128398:CURI RS11340
gene id: 1128398:CURI_RS11340
uniprot id: K0B182
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1128398:CURI RS15870
gene id: 1128398:CURI_RS15870
uniprot id: K0AY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1128398:CURI RS06225
gene id: 1128398:CURI_RS06225
uniprot id: K0AZN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS02155
gene id: 1128398:CURI_RS02155
uniprot id: K0AYM1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1128398:CURI RS01395
gene id: 1128398:CURI_RS01395
uniprot id: K0AX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS04210
gene id: 1128398:CURI_RS04210
uniprot id: K0AZ01
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1128398:CURI RS05035
gene id: 1128398:CURI_RS05035
uniprot id: K0B036
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS01720
gene id: 1128398:CURI_RS01720
uniprot id: K0AVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1128398:CURI RS01525
gene id: 1128398:CURI_RS01525
uniprot id: K0AYE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1128398:CURI RS06490
gene id: 1128398:CURI_RS06490
uniprot id: K0AZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00515
gene id: 1128398:CURI_RS00515
uniprot id: K0AXM5
names: Similarity
messages: Belongs to the class-I fumarase family.

1128398:CURI RS09285
gene id: 1128398:CURI_RS09285
uniprot id: K0B1B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1128398:CURI RS00345
gene id: 1128398:CURI_RS00345
uniprot id: K0AWK9
names: Similarity
messages: Belongs to the UPF0735 family.

1128398:CURI RS02540
gene id: 1128398:CURI_RS02540
uniprot id: K0AYS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1128398:CURI RS00695
gene id: 1128398:CURI_RS00695
uniprot id: K0AXS5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1128398:CURI RS00340
gene id: 1128398:CURI_RS00340
uniprot id: K0AXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1128398:CURI RS13940
gene id: 1128398:CURI_RS13940
uniprot id: K0B3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS02840
gene id: 1128398:CURI_RS02840
uniprot id: K0AWM5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1128398:CURI RS06900
gene id: 1128398:CURI_RS06900
uniprot id: K0B0E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1128398:CURI RS08690
gene id: 1128398:CURI_RS08690
uniprot id: K0AY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS01400
gene id: 1128398:CURI_RS01400
uniprot id: K0AYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS06535
gene id: 1128398:CURI_RS06535
uniprot id: K0AZU6
names: Similarity
messages: Belongs to the transpeptidase family.

1128398:CURI RS15095
gene id: 1128398:CURI_RS15095
uniprot id: K0B2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1128398:CURI RS02370
gene id: 1128398:CURI_RS02370
uniprot id: K0AXN5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS08445
gene id: 1128398:CURI_RS08445
uniprot id: K0B165
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1128398:CURI RS14675
gene id: 1128398:CURI_RS14675
uniprot id: K0B398
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1128398:CURI RS02290
gene id: 1128398:CURI_RS02290
uniprot id: K0AYN9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family. Cfr subfamily.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics.

1128398:CURI RS02770
gene id: 1128398:CURI_RS02770
uniprot id: K0AYY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS09075
gene id: 1128398:CURI_RS09075
uniprot id: K0B2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1128398:CURI RS10745
gene id: 1128398:CURI_RS10745
uniprot id: K0B209
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1128398:CURI RS06500
gene id: 1128398:CURI_RS06500
uniprot id: K0AYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1128398:CURI RS10125
gene id: 1128398:CURI_RS10125
uniprot id: K0B274
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS05060
gene id: 1128398:CURI_RS05060
uniprot id: K0B042
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS11595
gene id: 1128398:CURI_RS11595
uniprot id: K0B352
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1128398:CURI RS11255
gene id: 1128398:CURI_RS11255
uniprot id: K0B2B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1128398:CURI RS14680
gene id: 1128398:CURI_RS14680
uniprot id: K0B4U7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1128398:CURI RS12300
gene id: 1128398:CURI_RS12300
uniprot id: K0B4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS03460
gene id: 1128398:CURI_RS03460
uniprot id: K0AYC0
names: Similarity
messages: Belongs to the peptidase U62 family.

1128398:CURI RS07635
gene id: 1128398:CURI_RS07635
uniprot id: K0B0U0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1128398:CURI RS03910
gene id: 1128398:CURI_RS03910
uniprot id: K0AYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS13365
gene id: 1128398:CURI_RS13365
uniprot id: K0B0X1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1128398:CURI RS02090
gene id: 1128398:CURI_RS02090
uniprot id: K0AUG2
names: Similarity
messages: Belongs to the UPF0251 family.

1128398:CURI RS03650
gene id: 1128398:CURI_RS03650
uniprot id: K0AX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1128398:CURI RS08335
gene id: 1128398:CURI_RS08335
uniprot id: K0AXZ7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1128398:CURI RS03420
gene id: 1128398:CURI_RS03420
uniprot id: K0AYA1
names: Similarity
messages: Belongs to the TrpF family.

1128398:CURI RS06195
gene id: 1128398:CURI_RS06195
uniprot id: K0B0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1128398:CURI RS13775
gene id: 1128398:CURI_RS13775
uniprot id: K0B5D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1128398:CURI RS09125
gene id: 1128398:CURI_RS09125
uniprot id: K0B1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1128398:CURI RS03350
gene id: 1128398:CURI_RS03350
uniprot id: K0AZD7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1128398:CURI RS05695
gene id: 1128398:CURI_RS05695
uniprot id: K0AZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1128398:CURI RS08655
gene id: 1128398:CURI_RS08655
uniprot id: K0B261
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS00995
gene id: 1128398:CURI_RS00995
uniprot id: K0AX03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1128398:CURI RS11160
gene id: 1128398:CURI_RS11160
uniprot id: K0B145
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1128398:CURI RS11295
gene id: 1128398:CURI_RS11295
uniprot id: K0B2V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1128398:CURI RS11930
gene id: 1128398:CURI_RS11930
uniprot id: K0B4C0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06585
gene id: 1128398:CURI_RS06585
uniprot id: K0AZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1128398:CURI RS11175
gene id: 1128398:CURI_RS11175
uniprot id: K0B296
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1128398:CURI RS09910
gene id: 1128398:CURI_RS09910
uniprot id: K0B1L6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1128398:CURI RS09405
gene id: 1128398:CURI_RS09405
uniprot id: K0B1U0
names: Similarity
messages: Belongs to the ArsC family.

1128398:CURI RS10815
gene id: 1128398:CURI_RS10815
uniprot id: K0B3G8
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1128398:CURI RS08590
gene id: 1128398:CURI_RS08590
uniprot id: K0AY59
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1128398:CURI RS12190
gene id: 1128398:CURI_RS12190
uniprot id: K0B072
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1128398:CURI RS08465
gene id: 1128398:CURI_RS08465
uniprot id: K0AZK4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1128398:CURI RS11350
gene id: 1128398:CURI_RS11350
uniprot id: K0B3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1128398:CURI RS10165
gene id: 1128398:CURI_RS10165
uniprot id: K0AZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1128398:CURI RS06760
gene id: 1128398:CURI_RS06760
uniprot id: K0AX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1128398:CURI RS08795
gene id: 1128398:CURI_RS08795
uniprot id: K0B1C4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1128398:CURI RS11815
gene id: 1128398:CURI_RS11815
uniprot id: K0AZY7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1128398:CURI RS06590
gene id: 1128398:CURI_RS06590
uniprot id: K0AWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1128398:CURI RS11910
gene id: 1128398:CURI_RS11910
uniprot id: K0B2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1128398:CURI RS07265
gene id: 1128398:CURI_RS07265
uniprot id: K0AYX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1128398:CURI RS09870
gene id: 1128398:CURI_RS09870
uniprot id: K0B0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1128398:CURI RS01080
gene id: 1128398:CURI_RS01080
uniprot id: K0AWZ3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1128398:CURI RS14000
gene id: 1128398:CURI_RS14000
uniprot id: K0B2S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS13180
gene id: 1128398:CURI_RS13180
uniprot id: K0B4Y9
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

1128398:CURI RS08815
gene id: 1128398:CURI_RS08815
uniprot id: K0AZR5
names: Similarity
messages: Belongs to the peptidase M18 family.

1128398:CURI RS03145
gene id: 1128398:CURI_RS03145
uniprot id: K0AY51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1128398:CURI RS03090
gene id: 1128398:CURI_RS03090
uniprot id: K0AZ80
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1128398:CURI RS03060
gene id: 1128398:CURI_RS03060
uniprot id: K0AZ71
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS05445
gene id: 1128398:CURI_RS05445
uniprot id: K0B0B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1128398:CURI RS01540
gene id: 1128398:CURI_RS01540
uniprot id: K0AVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1128398:CURI RS01770
gene id: 1128398:CURI_RS01770
uniprot id: K0AW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS12325
gene id: 1128398:CURI_RS12325
uniprot id: K0B4J3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1128398:CURI RS05220
gene id: 1128398:CURI_RS05220
uniprot id: K0B071
names: Subcellular Location Annotation
messages: Cell membrane

1128398:CURI RS10930
gene id: 1128398:CURI_RS10930
uniprot id: K0B0Z7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1128398:CURI RS12310
gene id: 1128398:CURI_RS12310
uniprot id: K0B097
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS05380
gene id: 1128398:CURI_RS05380
uniprot id: K0AXZ5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS10705
gene id: 1128398:CURI_RS10705
uniprot id: K0B0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1128398:CURI RS09735
gene id: 1128398:CURI_RS09735
uniprot id: K0B202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1128398:CURI RS09450
gene id: 1128398:CURI_RS09450
uniprot id: K0B055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1128398:CURI RS06250
gene id: 1128398:CURI_RS06250
uniprot id: K0AZN8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1128398:CURI RS11215
gene id: 1128398:CURI_RS11215
uniprot id: K0B156
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1128398:CURI RS05635
gene id: 1128398:CURI_RS05635
uniprot id: K0AW87
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1128398:CURI RS07630
gene id: 1128398:CURI_RS07630
uniprot id: K0AZ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1128398:CURI RS09005
gene id: 1128398:CURI_RS09005
uniprot id: K0B159
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1128398:CURI RS08835
gene id: 1128398:CURI_RS08835
uniprot id: K0AYB5
names: Subcellular Location Annotation
messages: Cell membrane

1128398:CURI RS03985
gene id: 1128398:CURI_RS03985
uniprot id: K0AZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.

1128398:CURI RS13945
gene id: 1128398:CURI_RS13945
uniprot id: K0B191
names: Similarity
messages: Belongs to the FBPase class 3 family.

1128398:CURI RS05160
gene id: 1128398:CURI_RS05160
uniprot id: K0AZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1128398:CURI RS06125
gene id: 1128398:CURI_RS06125
uniprot id: K0AWL8
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS06270
gene id: 1128398:CURI_RS06270
uniprot id: K0B0S9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1128398:CURI RS12675
gene id: 1128398:CURI_RS12675
uniprot id: K0B4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1128398:CURI RS07240
gene id: 1128398:CURI_RS07240
uniprot id: K0AYX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1128398:CURI RS06975
gene id: 1128398:CURI_RS06975
uniprot id: K0B0H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1128398:CURI RS05745
gene id: 1128398:CURI_RS05745
uniprot id: K0AZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS13025
gene id: 1128398:CURI_RS13025
uniprot id: K0B3W4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1128398:CURI RS01325
gene id: 1128398:CURI_RS01325
uniprot id: K0AY90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1128398:CURI RS02900
gene id: 1128398:CURI_RS02900
uniprot id: K0AZ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1128398:CURI RS12235
gene id: 1128398:CURI_RS12235
uniprot id: K0B2T2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1128398:CURI RS09980
gene id: 1128398:CURI_RS09980
uniprot id: K0B2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1128398:CURI RS11370
gene id: 1128398:CURI_RS11370
uniprot id: K0B2Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1128398:CURI RS12090
gene id: 1128398:CURI_RS12090
uniprot id: K0B056
names: Similarity
messages: Belongs to the leucine-binding protein family.

1128398:CURI RS11965
gene id: 1128398:CURI_RS11965
uniprot id: K0B037
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1128398:CURI RS14325
gene id: 1128398:CURI_RS14325
uniprot id: K0B406
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1128398:CURI RS00350
gene id: 1128398:CURI_RS00350
uniprot id: K0ATG8
names: Similarity
messages: Belongs to the peptidase S49 family.

1128398:CURI RS05820
gene id: 1128398:CURI_RS05820
uniprot id: K0AZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS10445
gene id: 1128398:CURI_RS10445
uniprot id: K0B2D1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1128398:CURI RS06150
gene id: 1128398:CURI_RS06150
uniprot id: K0AZL8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1128398:CURI RS10175
gene id: 1128398:CURI_RS10175
uniprot id: K0B282
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS10670
gene id: 1128398:CURI_RS10670
uniprot id: K0B2H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1128398:CURI RS07065
gene id: 1128398:CURI_RS07065
uniprot id: K0AYU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1128398:CURI RS03345
gene id: 1128398:CURI_RS03345
uniprot id: K0AY99
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS07100
gene id: 1128398:CURI_RS07100
uniprot id: K0B0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1128398:CURI RS05485
gene id: 1128398:CURI_RS05485
uniprot id: K0AY10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS11245
gene id: 1128398:CURI_RS11245
uniprot id: K0B2T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1128398:CURI RS02050
gene id: 1128398:CURI_RS02050
uniprot id: K0AXM0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1128398:CURI RS03040
gene id: 1128398:CURI_RS03040
uniprot id: K0AY25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS03585
gene id: 1128398:CURI_RS03585
uniprot id: K0AYE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1128398:CURI RS07915
gene id: 1128398:CURI_RS07915
uniprot id: K0B0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1128398:CURI RS07765
gene id: 1128398:CURI_RS07765
uniprot id: K0B1J5
names: Similarity
messages: Belongs to the ribF family.

1128398:CURI RS08510
gene id: 1128398:CURI_RS08510
uniprot id: K0AY44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1128398:CURI RS14730
gene id: 1128398:CURI_RS14730
uniprot id: K0B3A6
names: Similarity
messages: Belongs to the ParB family.

1128398:CURI RS09330
gene id: 1128398:CURI_RS09330
uniprot id: K0B2P4
names: Similarity
messages: Belongs to the peptidase S66 family.

1128398:CURI RS12985
gene id: 1128398:CURI_RS12985
uniprot id: K0B336
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1128398:CURI RS12830
gene id: 1128398:CURI_RS12830
uniprot id: K0B306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS13065
gene id: 1128398:CURI_RS13065
uniprot id: K0B0Q5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1128398:CURI RS02940
gene id: 1128398:CURI_RS02940
uniprot id: K0AWP7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1128398:CURI RS05015
gene id: 1128398:CURI_RS05015
uniprot id: K0AVV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1128398:CURI RS11265
gene id: 1128398:CURI_RS11265
uniprot id: K0B167
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1128398:CURI RS06435
gene id: 1128398:CURI_RS06435
uniprot id: K0B0W5
names: Similarity
messages: Belongs to the GSP E family.

1128398:CURI RS07225
gene id: 1128398:CURI_RS07225
uniprot id: K0B1C2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1128398:CURI RS12170
gene id: 1128398:CURI_RS12170
uniprot id: K0B1U5
names: Similarity
messages: Belongs to the Fur family.

1128398:CURI RS10850
gene id: 1128398:CURI_RS10850
uniprot id: K0AZE5
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1128398:CURI RS10000
gene id: 1128398:CURI_RS10000
uniprot id: K0B252
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS04940
gene id: 1128398:CURI_RS04940
uniprot id: K0AVV1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1128398:CURI RS04875
gene id: 1128398:CURI_RS04875
uniprot id: K0AZ60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1128398:CURI RS07965
gene id: 1128398:CURI_RS07965
uniprot id: K0B0Z6
names: Similarity
messages: Belongs to the MotB family.

1128398:CURI RS14795
gene id: 1128398:CURI_RS14795
uniprot id: K0B479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1128398:CURI RS08425
gene id: 1128398:CURI_RS08425
uniprot id: K0B1Y1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1128398:CURI RS13475
gene id: 1128398:CURI_RS13475
uniprot id: K0B567
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1128398:CURI RS12025
gene id: 1128398:CURI_RS12025
uniprot id: K0B3I4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1128398:CURI RS10790
gene id: 1128398:CURI_RS10790
uniprot id: K0B3G2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1128398:CURI RS05205
gene id: 1128398:CURI_RS05205
uniprot id: K0AVY3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1128398:CURI RS03850
gene id: 1128398:CURI_RS03850
uniprot id: K0AVG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1128398:CURI RS05245
gene id: 1128398:CURI_RS05245
uniprot id: K0B075
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1128398:CURI RS02595
gene id: 1128398:CURI_RS02595
uniprot id: K0AXT3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1128398:CURI RS06220
gene id: 1128398:CURI_RS06220
uniprot id: K0B0R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1128398:CURI RS04035
gene id: 1128398:CURI_RS04035
uniprot id: K0AYM5
names: Similarity
messages: Belongs to the PemK/MazF family.

1128398:CURI RS09985
gene id: 1128398:CURI_RS09985
uniprot id: K0B1M6
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS14800
gene id: 1128398:CURI_RS14800
uniprot id: K0B1R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1128398:CURI RS11900
gene id: 1128398:CURI_RS11900
uniprot id: K0B3E1
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS02995
gene id: 1128398:CURI_RS02995
uniprot id: K0AUW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS11260
gene id: 1128398:CURI_RS11260
uniprot id: K0AZM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1128398:CURI RS12625
gene id: 1128398:CURI_RS12625
uniprot id: K0B4N5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1128398:CURI RS12650
gene id: 1128398:CURI_RS12650
uniprot id: K0B4N8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1128398:CURI RS00495
gene id: 1128398:CURI_RS00495
uniprot id: K0AXL9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1128398:CURI RS05915
gene id: 1128398:CURI_RS05915
uniprot id: K0AZH1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1128398:CURI RS11600
gene id: 1128398:CURI_RS11600
uniprot id: K0B432
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1128398:CURI RS08370
gene id: 1128398:CURI_RS08370
uniprot id: K0B153
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1128398:CURI RS05960
gene id: 1128398:CURI_RS05960
uniprot id: K0B0L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1128398:CURI RS07955
gene id: 1128398:CURI_RS07955
uniprot id: K0AXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1128398:CURI RS11970
gene id: 1128398:CURI_RS11970
uniprot id: K0B1Q6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1128398:CURI RS08485
gene id: 1128398:CURI_RS08485
uniprot id: K0AY37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1128398:CURI RS02265
gene id: 1128398:CURI_RS02265
uniprot id: K0AYN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS11305
gene id: 1128398:CURI_RS11305
uniprot id: K0B2C7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1128398:CURI RS10865
gene id: 1128398:CURI_RS10865
uniprot id: K0B3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1128398:CURI RS05795
gene id: 1128398:CURI_RS05795
uniprot id: K0AZL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1128398:CURI RS04135
gene id: 1128398:CURI_RS04135
uniprot id: K0AZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1128398:CURI RS06130
gene id: 1128398:CURI_RS06130
uniprot id: K0AYA0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS11205
gene id: 1128398:CURI_RS11205
uniprot id: K0B2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1128398:CURI RS06355
gene id: 1128398:CURI_RS06355
uniprot id: K0AYD5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS14550
gene id: 1128398:CURI_RS14550
uniprot id: K0B4P2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1128398:CURI RS07770
gene id: 1128398:CURI_RS07770
uniprot id: K0B0G7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1128398:CURI RS07215
gene id: 1128398:CURI_RS07215
uniprot id: K0AYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1128398:CURI RS11395
gene id: 1128398:CURI_RS11395
uniprot id: K0B2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1128398:CURI RS04400
gene id: 1128398:CURI_RS04400
uniprot id: K0AXP5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS09070
gene id: 1128398:CURI_RS09070
uniprot id: K0B1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1128398:CURI RS04365
gene id: 1128398:CURI_RS04365
uniprot id: K0AYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS11760
gene id: 1128398:CURI_RS11760
uniprot id: K0B471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS06990
gene id: 1128398:CURI_RS06990
uniprot id: K0AX91
names: Similarity
messages: Belongs to the TlyA family.

1128398:CURI RS10730
gene id: 1128398:CURI_RS10730
uniprot id: K0B0V2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS12760
gene id: 1128398:CURI_RS12760
uniprot id: K0B0I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1128398:CURI RS11120
gene id: 1128398:CURI_RS11120
uniprot id: K0B3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1128398:CURI RS12590
gene id: 1128398:CURI_RS12590
uniprot id: K0B217
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

1128398:CURI RS06005
gene id: 1128398:CURI_RS06005
uniprot id: K0AZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1128398:CURI RS02915
gene id: 1128398:CURI_RS02915
uniprot id: K0AWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1128398:CURI RS06155
gene id: 1128398:CURI_RS06155
uniprot id: K0AWM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1128398:CURI RS03570
gene id: 1128398:CURI_RS03570
uniprot id: K0AYD0
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1128398:CURI RS02845
gene id: 1128398:CURI_RS02845
uniprot id: K0AY09
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1128398:CURI RS11635
gene id: 1128398:CURI_RS11635
uniprot id: K0AZV3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1128398:CURI RS11165
gene id: 1128398:CURI_RS11165
uniprot id: K0B2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1128398:CURI RS00535
gene id: 1128398:CURI_RS00535
uniprot id: K0AWS9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1128398:CURI RS11250
gene id: 1128398:CURI_RS11250
uniprot id: K0B3T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1128398:CURI RS10195
gene id: 1128398:CURI_RS10195
uniprot id: K0B0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1128398:CURI RS05365
gene id: 1128398:CURI_RS05365
uniprot id: K0B0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1128398:CURI RS03625
gene id: 1128398:CURI_RS03625
uniprot id: K0AVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS06540
gene id: 1128398:CURI_RS06540
uniprot id: K0AWW5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS07795
gene id: 1128398:CURI_RS07795
uniprot id: K0B0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1128398:CURI RS11220
gene id: 1128398:CURI_RS11220
uniprot id: K0B2T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS07910
gene id: 1128398:CURI_RS07910
uniprot id: K0AZ94
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1128398:CURI RS00615
gene id: 1128398:CURI_RS00615
uniprot id: K0AXQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1128398:CURI RS10150
gene id: 1128398:CURI_RS10150
uniprot id: K0B278
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1128398:CURI RS10120
gene id: 1128398:CURI_RS10120
uniprot id: K0B0G2
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1128398:CURI RS00380
gene id: 1128398:CURI_RS00380
uniprot id: K0AV67
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1128398:CURI RS11385
gene id: 1128398:CURI_RS11385
uniprot id: K0AZQ3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1128398:CURI RS07920
gene id: 1128398:CURI_RS07920
uniprot id: K0B1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1128398:CURI RS08640
gene id: 1128398:CURI_RS08640
uniprot id: K0AY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1128398:CURI RS04330
gene id: 1128398:CURI_RS04330
uniprot id: K0AZ15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1128398:CURI RS09195
gene id: 1128398:CURI_RS09195
uniprot id: K0AYJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1128398:CURI RS09025
gene id: 1128398:CURI_RS09025
uniprot id: K0B2G6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1128398:CURI RS01890
gene id: 1128398:CURI_RS01890
uniprot id: K0AUD8
names: Similarity
messages: Belongs to the UPF0751 family.

1128398:CURI RS14610
gene id: 1128398:CURI_RS14610
uniprot id: K0B607
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS08915
gene id: 1128398:CURI_RS08915
uniprot id: K0AYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS00715
gene id: 1128398:CURI_RS00715
uniprot id: K0AWV9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1128398:CURI RS10080
gene id: 1128398:CURI_RS10080
uniprot id: K0B307
names: Similarity
messages: Belongs to the peptidase S11 family.

1128398:CURI RS13555
gene id: 1128398:CURI_RS13555
uniprot id: K0B3F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS10140
gene id: 1128398:CURI_RS10140
uniprot id: K0AYZ6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1128398:CURI RS02910
gene id: 1128398:CURI_RS02910
uniprot id: K0AUU6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1128398:CURI RS14295
gene id: 1128398:CURI_RS14295
uniprot id: K0B5S5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1128398:CURI RS01480
gene id: 1128398:CURI_RS01480
uniprot id: K0AX85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1128398:CURI RS11845
gene id: 1128398:CURI_RS11845
uniprot id: K0B1K9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1128398:CURI RS04880
gene id: 1128398:CURI_RS04880
uniprot id: K0B027
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS08120
gene id: 1128398:CURI_RS08120
uniprot id: K0B117
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1128398:CURI RS11620
gene id: 1128398:CURI_RS11620
uniprot id: K0B361
names: Similarity
messages: Belongs to the LOR family.

1128398:CURI RS02530
gene id: 1128398:CURI_RS02530
uniprot id: K0AWH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS13415
gene id: 1128398:CURI_RS13415
uniprot id: K0B0Y1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1128398:CURI RS03085
gene id: 1128398:CURI_RS03085
uniprot id: K0AY49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1128398:CURI RS05930
gene id: 1128398:CURI_RS05930
uniprot id: K0AZP0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1128398:CURI RS01010
gene id: 1128398:CURI_RS01010
uniprot id: K0ATV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1128398:CURI RS12060
gene id: 1128398:CURI_RS12060
uniprot id: K0B2R4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1128398:CURI RS12465
gene id: 1128398:CURI_RS12465
uniprot id: K0B3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1128398:CURI RS00725
gene id: 1128398:CURI_RS00725
uniprot id: K0AWS3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1128398:CURI RS14695
gene id: 1128398:CURI_RS14695
uniprot id: K0B1Q4
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1128398:CURI RS01160
gene id: 1128398:CURI_RS01160
uniprot id: K0AVL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS01910
gene id: 1128398:CURI_RS01910
uniprot id: K0AXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1128398:CURI RS13490
gene id: 1128398:CURI_RS13490
uniprot id: K0B2H0
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS04120
gene id: 1128398:CURI_RS04120
uniprot id: K0AVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS08430
gene id: 1128398:CURI_RS08430
uniprot id: K0B0T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1128398:CURI RS02700
gene id: 1128398:CURI_RS02700
uniprot id: K0AXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00745
gene id: 1128398:CURI_RS00745
uniprot id: K0AWW4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS13575
gene id: 1128398:CURI_RS13575
uniprot id: K0B592
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS02580
gene id: 1128398:CURI_RS02580
uniprot id: K0AXW8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1128398:CURI RS09310
gene id: 1128398:CURI_RS09310
uniprot id: K0B1C0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1128398:CURI RS05840
gene id: 1128398:CURI_RS05840
uniprot id: K0AY53
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1128398:CURI RS09265
gene id: 1128398:CURI_RS09265
uniprot id: K0B1A9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS14580
gene id: 1128398:CURI_RS14580
uniprot id: K0B5Y8
names: Similarity
messages: Belongs to the CdaR family.

1128398:CURI RS00490
gene id: 1128398:CURI_RS00490
uniprot id: K0AWS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1128398:CURI RS14790
gene id: 1128398:CURI_RS14790
uniprot id: K0B632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1128398:CURI RS01195
gene id: 1128398:CURI_RS01195
uniprot id: K0AY61
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1128398:CURI RS05495
gene id: 1128398:CURI_RS05495
uniprot id: K0B0C9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1128398:CURI RS08680
gene id: 1128398:CURI_RS08680
uniprot id: K0B267
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS03665
gene id: 1128398:CURI_RS03665
uniprot id: K0AYE7
names: Similarity
messages: Belongs to the GSP E family.

1128398:CURI RS11890
gene id: 1128398:CURI_RS11890
uniprot id: K0B006
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1128398:CURI RS11920
gene id: 1128398:CURI_RS11920
uniprot id: K0B1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1128398:CURI RS11445
gene id: 1128398:CURI_RS11445
uniprot id: K0B303
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1128398:CURI RS14050
gene id: 1128398:CURI_RS14050
uniprot id: K0B2U4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS03575
gene id: 1128398:CURI_RS03575
uniprot id: K0AV94
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1128398:CURI RS04140
gene id: 1128398:CURI_RS04140
uniprot id: K0AYP8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1128398:CURI RS06230
gene id: 1128398:CURI_RS06230
uniprot id: K0AWN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS15875
gene id: 1128398:CURI_RS15875
uniprot id: K0AZQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS09050
gene id: 1128398:CURI_RS09050
uniprot id: K0B2H2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1128398:CURI RS09470
gene id: 1128398:CURI_RS09470
uniprot id: K0AYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS06000
gene id: 1128398:CURI_RS06000
uniprot id: K0AY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1128398:CURI RS10280
gene id: 1128398:CURI_RS10280
uniprot id: K0B344
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1128398:CURI RS11590
gene id: 1128398:CURI_RS11590
uniprot id: K0B1E7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1128398:CURI RS04825
gene id: 1128398:CURI_RS04825
uniprot id: K0AZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS13550
gene id: 1128398:CURI_RS13550
uniprot id: K0B585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1128398:CURI RS08635
gene id: 1128398:CURI_RS08635
uniprot id: K0B0X8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1128398:CURI RS03215
gene id: 1128398:CURI_RS03215
uniprot id: K0AY75
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1128398:CURI RS06710
gene id: 1128398:CURI_RS06710
uniprot id: K0AX05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS10685
gene id: 1128398:CURI_RS10685
uniprot id: K0AZB1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS04950
gene id: 1128398:CURI_RS04950
uniprot id: K0AZ73
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1128398:CURI RS03610
gene id: 1128398:CURI_RS03610
uniprot id: K0AYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS05360
gene id: 1128398:CURI_RS05360
uniprot id: K0AZE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS00990
gene id: 1128398:CURI_RS00990
uniprot id: K0AVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1128398:CURI RS08960
gene id: 1128398:CURI_RS08960
uniprot id: K0B148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS01555
gene id: 1128398:CURI_RS01555
uniprot id: K0AXC0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1128398:CURI RS05085
gene id: 1128398:CURI_RS05085
uniprot id: K0B045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1128398:CURI RS05885
gene id: 1128398:CURI_RS05885
uniprot id: K0B0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS09415
gene id: 1128398:CURI_RS09415
uniprot id: K0B1F4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1128398:CURI RS06745
gene id: 1128398:CURI_RS06745
uniprot id: K0B067
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1128398:CURI RS01640
gene id: 1128398:CURI_RS01640
uniprot id: K0AUB1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1128398:CURI RS01410
gene id: 1128398:CURI_RS01410
uniprot id: K0AU49
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1128398:CURI RS13440
gene id: 1128398:CURI_RS13440
uniprot id: K0B0Y7
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS05170
gene id: 1128398:CURI_RS05170
uniprot id: K0AZ21
names: Similarity
messages: Belongs to the histone deacetylase family.

1128398:CURI RS01520
gene id: 1128398:CURI_RS01520
uniprot id: K0AXD9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1128398:CURI RS12365
gene id: 1128398:CURI_RS12365
uniprot id: K0B1Y0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1128398:CURI RS05855
gene id: 1128398:CURI_RS05855
uniprot id: K0AZF9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1128398:CURI RS01185
gene id: 1128398:CURI_RS01185
uniprot id: K0AVL4
names: Similarity
messages: Belongs to the FlgM family.

1128398:CURI RS00890
gene id: 1128398:CURI_RS00890
uniprot id: K0AVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1128398:CURI RS12750
gene id: 1128398:CURI_RS12750
uniprot id: K0B4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS03995
gene id: 1128398:CURI_RS03995
uniprot id: K0AXE2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1128398:CURI RS08350
gene id: 1128398:CURI_RS08350
uniprot id: K0B1V8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1128398:CURI RS06875
gene id: 1128398:CURI_RS06875
uniprot id: K0B0D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1128398:CURI RS05150
gene id: 1128398:CURI_RS05150
uniprot id: K0AVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS05350
gene id: 1128398:CURI_RS05350
uniprot id: K0AW07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1128398:CURI RS10845
gene id: 1128398:CURI_RS10845
uniprot id: K0B230
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1128398:CURI RS11540
gene id: 1128398:CURI_RS11540
uniprot id: K0B1D6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS11330
gene id: 1128398:CURI_RS11330
uniprot id: K0B2D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1128398:CURI RS13215
gene id: 1128398:CURI_RS13215
uniprot id: K0B2B9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS11170
gene id: 1128398:CURI_RS11170
uniprot id: K0B3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1128398:CURI RS03495
gene id: 1128398:CURI_RS03495
uniprot id: K0AYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1128398:CURI RS01055
gene id: 1128398:CURI_RS01055
uniprot id: K0AWY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS10315
gene id: 1128398:CURI_RS10315
uniprot id: K0AZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1128398:CURI RS01505
gene id: 1128398:CURI_RS01505
uniprot id: K0AX92
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1128398:CURI RS05045
gene id: 1128398:CURI_RS05045
uniprot id: K0AVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS05315
gene id: 1128398:CURI_RS05315
uniprot id: K0AZD4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1128398:CURI RS10190
gene id: 1128398:CURI_RS10190
uniprot id: K0AZ09
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1128398:CURI RS08470
gene id: 1128398:CURI_RS08470
uniprot id: K0B170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1128398:CURI RS00885
gene id: 1128398:CURI_RS00885
uniprot id: K0ATT2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1128398:CURI RS03300
gene id: 1128398:CURI_RS03300
uniprot id: K0AY83
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS04315
gene id: 1128398:CURI_RS04315
uniprot id: K0AYR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1128398:CURI RS11535
gene id: 1128398:CURI_RS11535
uniprot id: K0AZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1128398:CURI RS07860
gene id: 1128398:CURI_RS07860
uniprot id: K0AZ82
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1128398:CURI RS10805
gene id: 1128398:CURI_RS10805
uniprot id: K0B0X0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1128398:CURI RS02890
gene id: 1128398:CURI_RS02890
uniprot id: K0AWN5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1128398:CURI RS02820
gene id: 1128398:CURI_RS02820
uniprot id: K0AY06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1128398:CURI RS11615
gene id: 1128398:CURI_RS11615
uniprot id: K0B1F1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS06755
gene id: 1128398:CURI_RS06755
uniprot id: K0AZY8
names: Similarity
messages: Belongs to the Fur family.

1128398:CURI RS12890
gene id: 1128398:CURI_RS12890
uniprot id: K0B0K8
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS03295
gene id: 1128398:CURI_RS03295
uniprot id: K0AZC6
names: Similarity
messages: Belongs to the glutamate synthase family.

1128398:CURI RS03560
gene id: 1128398:CURI_RS03560
uniprot id: K0AYE1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1128398:CURI RS00525
gene id: 1128398:CURI_RS00525
uniprot id: K0ATK5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1128398:CURI RS04815
gene id: 1128398:CURI_RS04815
uniprot id: K0AVT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1128398:CURI RS10300
gene id: 1128398:CURI_RS10300
uniprot id: K0B2A5
names: Similarity
messages: Belongs to the peptidase S41A family.

1128398:CURI RS01025
gene id: 1128398:CURI_RS01025
uniprot id: K0AY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1128398:CURI RS12705
gene id: 1128398:CURI_RS12705
uniprot id: K0B2Z0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1128398:CURI RS08345
gene id: 1128398:CURI_RS08345
uniprot id: K0B151
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1128398:CURI RS01705
gene id: 1128398:CURI_RS01705
uniprot id: K0AXD4
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS11820
gene id: 1128398:CURI_RS11820
uniprot id: K0B1K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS11285
gene id: 1128398:CURI_RS11285
uniprot id: K0AZN1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1128398:CURI RS02725
gene id: 1128398:CURI_RS02725
uniprot id: K0AXV9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS10935
gene id: 1128398:CURI_RS10935
uniprot id: K0B2M2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS09900
gene id: 1128398:CURI_RS09900
uniprot id: K0B229
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1128398:CURI RS00985
gene id: 1128398:CURI_RS00985
uniprot id: K0ATV3
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS03955
gene id: 1128398:CURI_RS03955
uniprot id: K0AXC5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS03100
gene id: 1128398:CURI_RS03100
uniprot id: K0AUY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1128398:CURI RS13340
gene id: 1128398:CURI_RS13340
uniprot id: K0B0W4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS06950
gene id: 1128398:CURI_RS06950
uniprot id: K0B0H4
names: Similarity
messages: Belongs to the asp23 family.

1128398:CURI RS13250
gene id: 1128398:CURI_RS13250
uniprot id: K0B506
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS09630
gene id: 1128398:CURI_RS09630
uniprot id: K0B1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS08865
gene id: 1128398:CURI_RS08865
uniprot id: K0AZS5
names: Similarity
messages: Belongs to the ThiD family.

1128398:CURI RS02165
gene id: 1128398:CURI_RS02165
uniprot id: K0AUH1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1128398:CURI RS08135
gene id: 1128398:CURI_RS08135
uniprot id: K0AXU8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1128398:CURI RS13635
gene id: 1128398:CURI_RS13635
uniprot id: K0B127
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1128398:CURI RS01475
gene id: 1128398:CURI_RS01475
uniprot id: K0AYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1128398:CURI RS02775
gene id: 1128398:CURI_RS02775
uniprot id: K0AXW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1128398:CURI RS06305
gene id: 1128398:CURI_RS06305
uniprot id: K0AWQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS10920
gene id: 1128398:CURI_RS10920
uniprot id: K0B244
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS05375
gene id: 1128398:CURI_RS05375
uniprot id: K0AW14
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS02880
gene id: 1128398:CURI_RS02880
uniprot id: K0AXZ1
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS08585
gene id: 1128398:CURI_RS08585
uniprot id: K0B0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1128398:CURI RS06800
gene id: 1128398:CURI_RS06800
uniprot id: K0B094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1128398:CURI RS05280
gene id: 1128398:CURI_RS05280
uniprot id: K0AVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1128398:CURI RS11100
gene id: 1128398:CURI_RS11100
uniprot id: K0AZJ7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1128398:CURI RS09040
gene id: 1128398:CURI_RS09040
uniprot id: K0AZV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS10590
gene id: 1128398:CURI_RS10590
uniprot id: K0B0S0
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS06720
gene id: 1128398:CURI_RS06720
uniprot id: K0B057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1128398:CURI RS07730
gene id: 1128398:CURI_RS07730
uniprot id: K0AZ59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1128398:CURI RS07185
gene id: 1128398:CURI_RS07185
uniprot id: K0AXB2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1128398:CURI RS02410
gene id: 1128398:CURI_RS02410
uniprot id: K0AXT5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS14515
gene id: 1128398:CURI_RS14515
uniprot id: K0B1L1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1128398:CURI RS00175
gene id: 1128398:CURI_RS00175
uniprot id: K0AWI0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1128398:CURI RS09220
gene id: 1128398:CURI_RS09220
uniprot id: K0AYK2
names: Similarity
messages: Belongs to the hemerythrin family.

1128398:CURI RS00070
gene id: 1128398:CURI_RS00070
uniprot id: K0AXC2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1128398:CURI RS00420
gene id: 1128398:CURI_RS00420
uniprot id: K0AWM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1128398:CURI RS08925
gene id: 1128398:CURI_RS08925
uniprot id: K0B1F0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1128398:CURI RS00410
gene id: 1128398:CURI_RS00410
uniprot id: K0AWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1128398:CURI RS04375
gene id: 1128398:CURI_RS04375
uniprot id: K0AXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1128398:CURI RS09020
gene id: 1128398:CURI_RS09020
uniprot id: K0B1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1128398:CURI RS08045
gene id: 1128398:CURI_RS08045
uniprot id: K0B1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1128398:CURI RS12135
gene id: 1128398:CURI_RS12135
uniprot id: K0B2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1128398:CURI RS04160
gene id: 1128398:CURI_RS04160
uniprot id: K0AZX7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1128398:CURI RS09150
gene id: 1128398:CURI_RS09150
uniprot id: K0B1K8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1128398:CURI RS03670
gene id: 1128398:CURI_RS03670
uniprot id: K0AVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS11180
gene id: 1128398:CURI_RS11180
uniprot id: K0AZL2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1128398:CURI RS00270
gene id: 1128398:CURI_RS00270
uniprot id: K0AWM8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS07745
gene id: 1128398:CURI_RS07745
uniprot id: K0B0G3
names: Similarity
messages: Belongs to the peptidase M16 family.

1128398:CURI RS12215
gene id: 1128398:CURI_RS12215
uniprot id: K0B077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS07780
gene id: 1128398:CURI_RS07780
uniprot id: K0AZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1128398:CURI RS13140
gene id: 1128398:CURI_RS13140
uniprot id: K0B0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1128398:CURI RS07595
gene id: 1128398:CURI_RS07595
uniprot id: K0B0E0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1128398:CURI RS09165
gene id: 1128398:CURI_RS09165
uniprot id: K0B187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1128398:CURI RS08340
gene id: 1128398:CURI_RS08340
uniprot id: K0AZH6
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1128398:CURI RS00140
gene id: 1128398:CURI_RS00140
uniprot id: K0AWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1128398:CURI RS10285
gene id: 1128398:CURI_RS10285
uniprot id: K0B1R4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1128398:CURI RS02085
gene id: 1128398:CURI_RS02085
uniprot id: K0AXI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1128398:CURI RS07235
gene id: 1128398:CURI_RS07235
uniprot id: K0AXB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1128398:CURI RS10345
gene id: 1128398:CURI_RS10345
uniprot id: K0B0K9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1128398:CURI RS01385
gene id: 1128398:CURI_RS01385
uniprot id: K0AU44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1128398:CURI RS13470
gene id: 1128398:CURI_RS13470
uniprot id: K0B430
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS08110
gene id: 1128398:CURI_RS08110
uniprot id: K0AXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1128398:CURI RS13650
gene id: 1128398:CURI_RS13650
uniprot id: K0B5A7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1128398:CURI RS01035
gene id: 1128398:CURI_RS01035
uniprot id: K0ATW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS02745
gene id: 1128398:CURI_RS02745
uniprot id: K0AYY3
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS02945
gene id: 1128398:CURI_RS02945
uniprot id: K0AY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS00355
gene id: 1128398:CURI_RS00355
uniprot id: K0AV61
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS07850
gene id: 1128398:CURI_RS07850
uniprot id: K0B0H9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06580
gene id: 1128398:CURI_RS06580
uniprot id: K0B0Z3
names: Similarity
messages: Belongs to the UPF0749 family.

1128398:CURI RS14315
gene id: 1128398:CURI_RS14315
uniprot id: K0B4K7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1128398:CURI RS03465
gene id: 1128398:CURI_RS03465
uniprot id: K0AZF8
names: Similarity
messages: Belongs to the peptidase U62 family.

1128398:CURI RS10775
gene id: 1128398:CURI_RS10775
uniprot id: K0AZD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1128398:CURI RS08440
gene id: 1128398:CURI_RS08440
uniprot id: K0AZJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS01790
gene id: 1128398:CURI_RS01790
uniprot id: K0AUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00125
gene id: 1128398:CURI_RS00125
uniprot id: K0AWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1128398:CURI RS06660
gene id: 1128398:CURI_RS06660
uniprot id: K0AWZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1128398:CURI RS14775
gene id: 1128398:CURI_RS14775
uniprot id: K0B1R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06730
gene id: 1128398:CURI_RS06730
uniprot id: K0AZY1
names: Similarity
messages: Belongs to the UPF0297 family.

1128398:CURI RS11115
gene id: 1128398:CURI_RS11115
uniprot id: K0B2Q5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS08005
gene id: 1128398:CURI_RS08005
uniprot id: K0AXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS07970
gene id: 1128398:CURI_RS07970
uniprot id: K0B1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1128398:CURI RS07930
gene id: 1128398:CURI_RS07930
uniprot id: K0AXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1128398:CURI RS12655
gene id: 1128398:CURI_RS12655
uniprot id: K0B2Y5
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1128398:CURI RS12805
gene id: 1128398:CURI_RS12805
uniprot id: K0B302
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1128398:CURI RS07725
gene id: 1128398:CURI_RS07725
uniprot id: K0AXK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1128398:CURI RS08970
gene id: 1128398:CURI_RS08970
uniprot id: K0AZU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1128398:CURI RS01340
gene id: 1128398:CURI_RS01340
uniprot id: K0AVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1128398:CURI RS02905
gene id: 1128398:CURI_RS02905
uniprot id: K0AXZ6
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1128398:CURI RS07720
gene id: 1128398:CURI_RS07720
uniprot id: K0B0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1128398:CURI RS13185
gene id: 1128398:CURI_RS13185
uniprot id: K0B378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS14655
gene id: 1128398:CURI_RS14655
uniprot id: K0B4U4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1128398:CURI RS00370
gene id: 1128398:CURI_RS00370
uniprot id: K0AWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1128398:CURI RS07600
gene id: 1128398:CURI_RS07600
uniprot id: K0AXH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1128398:CURI RS03415
gene id: 1128398:CURI_RS03415
uniprot id: K0AZE7
names: Similarity
messages: Belongs to the TrpC family.

1128398:CURI RS03940
gene id: 1128398:CURI_RS03940
uniprot id: K0AZR9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS12515
gene id: 1128398:CURI_RS12515
uniprot id: K0B203
names: Similarity
messages: Belongs to the AOR/FOR family.

1128398:CURI RS04200
gene id: 1128398:CURI_RS04200
uniprot id: K0AVN9
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1128398:CURI RS13460
gene id: 1128398:CURI_RS13460
uniprot id: K0B0Z1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1128398:CURI RS01490
gene id: 1128398:CURI_RS01490
uniprot id: K0AVT3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1128398:CURI RS11800
gene id: 1128398:CURI_RS11800
uniprot id: K0B3A9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS07755
gene id: 1128398:CURI_RS07755
uniprot id: K0AZ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1128398:CURI RS01360
gene id: 1128398:CURI_RS01360
uniprot id: K0AU39
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS00900
gene id: 1128398:CURI_RS00900
uniprot id: K0AXX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS05505
gene id: 1128398:CURI_RS05505
uniprot id: K0AW49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1128398:CURI RS12175
gene id: 1128398:CURI_RS12175
uniprot id: K0B3K2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS03315
gene id: 1128398:CURI_RS03315
uniprot id: K0AY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1128398:CURI RS12340
gene id: 1128398:CURI_RS12340
uniprot id: K0B1X6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1128398:CURI RS02720
gene id: 1128398:CURI_RS02720
uniprot id: K0AYX7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS07010
gene id: 1128398:CURI_RS07010
uniprot id: K0B047
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1128398:CURI RS05665
gene id: 1128398:CURI_RS05665
uniprot id: K0AY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1128398:CURI RS05520
gene id: 1128398:CURI_RS05520
uniprot id: K0B0D4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1128398:CURI RS09215
gene id: 1128398:CURI_RS09215
uniprot id: K0B198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1128398:CURI RS04350
gene id: 1128398:CURI_RS04350
uniprot id: K0AXN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1128398:CURI RS11270
gene id: 1128398:CURI_RS11270
uniprot id: K0B2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1128398:CURI RS07095
gene id: 1128398:CURI_RS07095
uniprot id: K0AYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS12130
gene id: 1128398:CURI_RS12130
uniprot id: K0B4G9
names: Similarity
messages: Belongs to the CvfB family.

1128398:CURI RS06995
gene id: 1128398:CURI_RS06995
uniprot id: K0AYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1128398:CURI RS04915
gene id: 1128398:CURI_RS04915
uniprot id: K0AVU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS14760
gene id: 1128398:CURI_RS14760
uniprot id: K0B4W0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1128398:CURI RS01670
gene id: 1128398:CURI_RS01670
uniprot id: K0AXG3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS13075
gene id: 1128398:CURI_RS13075
uniprot id: K0B3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS12915
gene id: 1128398:CURI_RS12915
uniprot id: K0B0L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS01465
gene id: 1128398:CURI_RS01465
uniprot id: K0AVS6
names: Subcellular Location Annotation
messages: cell wall

1128398:CURI RS01275
gene id: 1128398:CURI_RS01275
uniprot id: K0AY79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1128398:CURI RS08630
gene id: 1128398:CURI_RS08630
uniprot id: K0B253
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS02480
gene id: 1128398:CURI_RS02480
uniprot id: K0AWG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS07855
gene id: 1128398:CURI_RS07855
uniprot id: K0AXN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1128398:CURI RS14535
gene id: 1128398:CURI_RS14535
uniprot id: K0B428
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1128398:CURI RS00385
gene id: 1128398:CURI_RS00385
uniprot id: K0AWQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1128398:CURI RS04835
gene id: 1128398:CURI_RS04835
uniprot id: K0AYV8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1128398:CURI RS10310
gene id: 1128398:CURI_RS10310
uniprot id: K0B1R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1128398:CURI RS06775
gene id: 1128398:CURI_RS06775
uniprot id: K0B084
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1128398:CURI RS08070
gene id: 1128398:CURI_RS08070
uniprot id: K0B1P4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1128398:CURI RS04000
gene id: 1128398:CURI_RS04000
uniprot id: K0AYS5
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1128398:CURI RS14590
gene id: 1128398:CURI_RS14590
uniprot id: K0B1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1128398:CURI RS12225
gene id: 1128398:CURI_RS12225
uniprot id: K0B3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS04005
gene id: 1128398:CURI_RS04005
uniprot id: K0AZT4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1128398:CURI RS05055
gene id: 1128398:CURI_RS05055
uniprot id: K0AZ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1128398:CURI RS00660
gene id: 1128398:CURI_RS00660
uniprot id: K0AVB2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1128398:CURI RS13210
gene id: 1128398:CURI_RS13210
uniprot id: K0B0T8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1128398:CURI RS06170
gene id: 1128398:CURI_RS06170
uniprot id: K0B0Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS02920
gene id: 1128398:CURI_RS02920
uniprot id: K0AY26
names: Similarity
messages: Belongs to the pirin family.

1128398:CURI RS10050
gene id: 1128398:CURI_RS10050
uniprot id: K0B264
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1128398:CURI RS13810
gene id: 1128398:CURI_RS13810
uniprot id: K0B166
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS05905
gene id: 1128398:CURI_RS05905
uniprot id: K0AZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1128398:CURI RS11280
gene id: 1128398:CURI_RS11280
uniprot id: K0B2C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1128398:CURI RS06145
gene id: 1128398:CURI_RS06145
uniprot id: K0B0Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1128398:CURI RS06620
gene id: 1128398:CURI_RS06620
uniprot id: K0AYI8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1128398:CURI RS06970
gene id: 1128398:CURI_RS06970
uniprot id: K0AYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1128398:CURI RS10025
gene id: 1128398:CURI_RS10025
uniprot id: K0B258
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS11945
gene id: 1128398:CURI_RS11945
uniprot id: K0B1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1128398:CURI RS05935
gene id: 1128398:CURI_RS05935
uniprot id: K0B0L4
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS11230
gene id: 1128398:CURI_RS11230
uniprot id: K0B2A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1128398:CURI RS09770
gene id: 1128398:CURI_RS09770
uniprot id: K0B1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS08160
gene id: 1128398:CURI_RS08160
uniprot id: K0AXV5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1128398:CURI RS07655
gene id: 1128398:CURI_RS07655
uniprot id: K0AZ47
names: Similarity
messages: Belongs to the peptidase C40 family.

1128398:CURI RS08055
gene id: 1128398:CURI_RS08055
uniprot id: K0AXS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1128398:CURI RS03005
gene id: 1128398:CURI_RS03005
uniprot id: K0AY39
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS06245
gene id: 1128398:CURI_RS06245
uniprot id: K0B0S2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS00620
gene id: 1128398:CURI_RS00620
uniprot id: K0AWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1128398:CURI RS08185
gene id: 1128398:CURI_RS08185
uniprot id: K0AXW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1128398:CURI RS14135
gene id: 1128398:CURI_RS14135
uniprot id: K0B1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1128398:CURI RS08130
gene id: 1128398:CURI_RS08130
uniprot id: K0B0N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1128398:CURI RS01495
gene id: 1128398:CURI_RS01495
uniprot id: K0AXB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1128398:CURI RS11275
gene id: 1128398:CURI_RS11275
uniprot id: K0B3U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1128398:CURI RS10690
gene id: 1128398:CURI_RS10690
uniprot id: K0B0U2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1128398:CURI RS04855
gene id: 1128398:CURI_RS04855
uniprot id: K0B024
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS09535
gene id: 1128398:CURI_RS09535
uniprot id: K0B2T8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS08040
gene id: 1128398:CURI_RS08040
uniprot id: K0B105
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1128398:CURI RS06555
gene id: 1128398:CURI_RS06555
uniprot id: K0B0Y9
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS07825
gene id: 1128398:CURI_RS07825
uniprot id: K0B0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1128398:CURI RS05790
gene id: 1128398:CURI_RS05790
uniprot id: K0AY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS11975
gene id: 1128398:CURI_RS11975
uniprot id: K0B3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1128398:CURI RS13195
gene id: 1128398:CURI_RS13195
uniprot id: K0B2B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS02555
gene id: 1128398:CURI_RS02555
uniprot id: K0AWH5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1128398:CURI RS09705
gene id: 1128398:CURI_RS09705
uniprot id: K0B1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1128398:CURI RS06965
gene id: 1128398:CURI_RS06965
uniprot id: K0AX89
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1128398:CURI RS05295
gene id: 1128398:CURI_RS05295
uniprot id: K0B085
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1128398:CURI RS08115
gene id: 1128398:CURI_RS08115
uniprot id: K0AZD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1128398:CURI RS08025
gene id: 1128398:CURI_RS08025
uniprot id: K0B0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1128398:CURI RS05000
gene id: 1128398:CURI_RS05000
uniprot id: K0AZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1128398:CURI RS00840
gene id: 1128398:CURI_RS00840
uniprot id: K0AVE2
names: Similarity
messages: Belongs to the peptidase S41A family.

1128398:CURI RS11300
gene id: 1128398:CURI_RS11300
uniprot id: K0B3V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1128398:CURI RS09275
gene id: 1128398:CURI_RS09275
uniprot id: K0B1N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1128398:CURI RS00780
gene id: 1128398:CURI_RS00780
uniprot id: K0AWT3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1128398:CURI RS00720
gene id: 1128398:CURI_RS00720
uniprot id: K0AXT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1128398:CURI RS08685
gene id: 1128398:CURI_RS08685
uniprot id: K0B0Z0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1128398:CURI RS04785
gene id: 1128398:CURI_RS04785
uniprot id: K0B016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1128398:CURI RS03540
gene id: 1128398:CURI_RS03540
uniprot id: K0AZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS11400
gene id: 1128398:CURI_RS11400
uniprot id: K0B3Y1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1128398:CURI RS02045
gene id: 1128398:CURI_RS02045
uniprot id: K0AW86
names: Similarity
messages: Belongs to the WrbA family.

1128398:CURI RS12990
gene id: 1128398:CURI_RS12990
uniprot id: K0B0N5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1128398:CURI RS05420
gene id: 1128398:CURI_RS05420
uniprot id: K0B0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1128398:CURI RS04820
gene id: 1128398:CURI_RS04820
uniprot id: K0AXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS12430
gene id: 1128398:CURI_RS12430
uniprot id: K0B0C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1128398:CURI RS09885
gene id: 1128398:CURI_RS09885
uniprot id: K0B1L2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1128398:CURI RS05970
gene id: 1128398:CURI_RS05970
uniprot id: K0AWI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS01075
gene id: 1128398:CURI_RS01075
uniprot id: K0AY24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1128398:CURI RS03565
gene id: 1128398:CURI_RS03565
uniprot id: K0AZH9
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1128398:CURI RS06185
gene id: 1128398:CURI_RS06185
uniprot id: K0AYA8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1128398:CURI RS01170
gene id: 1128398:CURI_RS01170
uniprot id: K0AY55
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1128398:CURI RS13005
gene id: 1128398:CURI_RS13005
uniprot id: K0B4U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1128398:CURI RS13745
gene id: 1128398:CURI_RS13745
uniprot id: K0B475
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1128398:CURI RS07935
gene id: 1128398:CURI_RS07935
uniprot id: K0AZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1128398:CURI RS02785
gene id: 1128398:CURI_RS02785
uniprot id: K0AUS2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1128398:CURI RS04920
gene id: 1128398:CURI_RS04920
uniprot id: K0AXT0
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS12320
gene id: 1128398:CURI_RS12320
uniprot id: K0B3M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1128398:CURI RS13580
gene id: 1128398:CURI_RS13580
uniprot id: K0B3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1128398:CURI RS12195
gene id: 1128398:CURI_RS12195
uniprot id: K0B1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS13790
gene id: 1128398:CURI_RS13790
uniprot id: K0B2N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS06645
gene id: 1128398:CURI_RS06645
uniprot id: K0AYJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1128398:CURI RS00135
gene id: 1128398:CURI_RS00135
uniprot id: K0AV18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1128398:CURI RS04205
gene id: 1128398:CURI_RS04205
uniprot id: K0AXL8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1128398:CURI RS02825
gene id: 1128398:CURI_RS02825
uniprot id: K0AZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1128398:CURI RS14630
gene id: 1128398:CURI_RS14630
uniprot id: K0B4U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1128398:CURI RS07760
gene id: 1128398:CURI_RS07760
uniprot id: K0B0W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1128398:CURI RS07070
gene id: 1128398:CURI_RS07070
uniprot id: K0B0J2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1128398:CURI RS01850
gene id: 1128398:CURI_RS01850
uniprot id: K0AXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1128398:CURI RS04325
gene id: 1128398:CURI_RS04325
uniprot id: K0AXN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1128398:CURI RS11985
gene id: 1128398:CURI_RS11985
uniprot id: K0B2Q8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1128398:CURI RS13015
gene id: 1128398:CURI_RS13015
uniprot id: K0B0P2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1128398:CURI RS07255
gene id: 1128398:CURI_RS07255
uniprot id: K0B087
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS08100
gene id: 1128398:CURI_RS08100
uniprot id: K0B1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1128398:CURI RS08050
gene id: 1128398:CURI_RS08050
uniprot id: K0B0M1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1128398:CURI RS05010
gene id: 1128398:CURI_RS05010
uniprot id: K0AYY7
names: Similarity
messages: Belongs to the NadC/ModD family.

1128398:CURI RS08480
gene id: 1128398:CURI_RS08480
uniprot id: K0B0U6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1128398:CURI RS08565
gene id: 1128398:CURI_RS08565
uniprot id: K0AY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS02060
gene id: 1128398:CURI_RS02060
uniprot id: K0AXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS08155
gene id: 1128398:CURI_RS08155
uniprot id: K0B0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1128398:CURI RS12185
gene id: 1128398:CURI_RS12185
uniprot id: K0B2S6
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS10765
gene id: 1128398:CURI_RS10765
uniprot id: K0B3F7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1128398:CURI RS03220
gene id: 1128398:CURI_RS03220
uniprot id: K0AZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS01745
gene id: 1128398:CURI_RS01745
uniprot id: K0AW01
names: Similarity
messages: Belongs to the peptidase M24B family.

1128398:CURI RS11840
gene id: 1128398:CURI_RS11840
uniprot id: K0AZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1128398:CURI RS09730
gene id: 1128398:CURI_RS09730
uniprot id: K0B099
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1128398:CURI RS04355
gene id: 1128398:CURI_RS04355
uniprot id: K0AZ19
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1128398:CURI RS14820
gene id: 1128398:CURI_RS14820
uniprot id: K0B4W7
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

1128398:CURI RS11380
gene id: 1128398:CURI_RS11380
uniprot id: K0B2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1128398:CURI RS12100
gene id: 1128398:CURI_RS12100
uniprot id: K0B3J3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1128398:CURI RS04335
gene id: 1128398:CURI_RS04335
uniprot id: K0AZZ5
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS03535
gene id: 1128398:CURI_RS03535
uniprot id: K0AYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1128398:CURI RS11335
gene id: 1128398:CURI_RS11335
uniprot id: K0AZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1128398:CURI RS00970
gene id: 1128398:CURI_RS00970
uniprot id: K0AWZ8
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS08800
gene id: 1128398:CURI_RS08800
uniprot id: K0B2A3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1128398:CURI RS08730
gene id: 1128398:CURI_RS08730
uniprot id: K0B281
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1128398:CURI RS06055
gene id: 1128398:CURI_RS06055
uniprot id: K0AZR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS07960
gene id: 1128398:CURI_RS07960
uniprot id: K0AZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1128398:CURI RS05875
gene id: 1128398:CURI_RS05875
uniprot id: K0AY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS00775
gene id: 1128398:CURI_RS00775
uniprot id: K0AXU5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1128398:CURI RS10855
gene id: 1128398:CURI_RS10855
uniprot id: K0B0X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1128398:CURI RS00955
gene id: 1128398:CURI_RS00955
uniprot id: K0AWW6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1128398:CURI RS00180
gene id: 1128398:CURI_RS00180
uniprot id: K0ATC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1128398:CURI RS08475
gene id: 1128398:CURI_RS08475
uniprot id: K0B204
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1128398:CURI RS01370
gene id: 1128398:CURI_RS01370
uniprot id: K0AX83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1128398:CURI RS12440
gene id: 1128398:CURI_RS12440
uniprot id: K0B3P0
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1128398:CURI RS00360
gene id: 1128398:CURI_RS00360
uniprot id: K0AWP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1128398:CURI RS08175
gene id: 1128398:CURI_RS08175
uniprot id: K0B1R7
names: Similarity
messages: Belongs to the fabD family.

1128398:CURI RS10470
gene id: 1128398:CURI_RS10470
uniprot id: K0B2D6
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS09440
gene id: 1128398:CURI_RS09440
uniprot id: K0B1G0
names: Similarity
messages: Belongs to the EamA transporter family.

1128398:CURI RS11375
gene id: 1128398:CURI_RS11375
uniprot id: K0B3X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1128398:CURI RS14270
gene id: 1128398:CURI_RS14270
uniprot id: K0B5R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1128398:CURI RS14560
gene id: 1128398:CURI_RS14560
uniprot id: K0B433
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1128398:CURI RS14130
gene id: 1128398:CURI_RS14130
uniprot id: K0B3V9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1128398:CURI RS09670
gene id: 1128398:CURI_RS09670
uniprot id: K0AYT3
names: Subcellular Location Annotation
messages: Cytoplasm

1128398:CURI RS11235
gene id: 1128398:CURI_RS11235
uniprot id: K0AZM2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1128398:CURI RS08020
gene id: 1128398:CURI_RS08020
uniprot id: K0B1N7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1128398:CURI RS11925
gene id: 1128398:CURI_RS11925
uniprot id: K0B3E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1128398:CURI RS07950
gene id: 1128398:CURI_RS07950
uniprot id: K0B0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1128398:CURI RS11545
gene id: 1128398:CURI_RS11545
uniprot id: K0B338
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1128398:CURI RS12885
gene id: 1128398:CURI_RS12885
uniprot id: K0B313
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS01435
gene id: 1128398:CURI_RS01435
uniprot id: K0AU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1128398:CURI RS07045
gene id: 1128398:CURI_RS07045
uniprot id: K0B0J0
names: Subcellular Location Annotation
messages: Membrane

1128398:CURI RS06595
gene id: 1128398:CURI_RS06595
uniprot id: K0AYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1128398:CURI RS05080
gene id: 1128398:CURI_RS05080
uniprot id: K0AZ96
names: Similarity
messages: Belongs to the UPF0758 family.

1128398:CURI RS08715
gene id: 1128398:CURI_RS08715
uniprot id: K0AY86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1128398:CURI RS06785
gene id: 1128398:CURI_RS06785
uniprot id: K0AZZ4
names: Similarity
messages: Belongs to the transpeptidase family.

1128398:CURI RS11560
gene id: 1128398:CURI_RS11560
uniprot id: K0AZT8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1128398:CURI RS09650
gene id: 1128398:CURI_RS09650
uniprot id: K0B086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1128398:CURI RS01550
gene id: 1128398:CURI_RS01550
uniprot id: K0AYE9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1128398:CURI RS02705
gene id: 1128398:CURI_RS02705
uniprot id: K0AUQ8
names: Similarity
messages: Belongs to the glutamate synthase family.

1128398:CURI RS08790
gene id: 1128398:CURI_RS08790
uniprot id: K0AZR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1128398:CURI RS00925
gene id: 1128398:CURI_RS00925
uniprot id: K0AXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1128398:CURI RS04255
gene id: 1128398:CURI_RS04255
uniprot id: K0AXM6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1128398:CURI RS08210
gene id: 1128398:CURI_RS08210
uniprot id: K0B0P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1128398:CURI RS10435
gene id: 1128398:CURI_RS10435
uniprot id: K0AZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm
messages: Homotetramer.
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1128398:CURI RS05385
gene id: 1128398:CURI_RS05385
uniprot id: K0AZE9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1128398:CURI RS06475
gene id: 1128398:CURI_RS06475
uniprot id: K0AYF5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1128398:CURI RS04040
gene id: 1128398:CURI_RS04040
uniprot id: K0AVK4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.