1125411:W908 RS04150
gene id: 1125411:W908_RS04150
uniprot id: A0A0M4LD83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1125411:W908 RS07145
gene id: 1125411:W908_RS07145
uniprot id: A0A0M4M3K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1125411:W908 RS02435
gene id: 1125411:W908_RS02435
uniprot id: A0A0M3T1S1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1125411:W908 RS07205
gene id: 1125411:W908_RS07205
uniprot id: A0A0M4L678
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1125411:W908 RS02900
gene id: 1125411:W908_RS02900
uniprot id: A0A0M4LF16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1125411:W908 RS06640
gene id: 1125411:W908_RS06640
uniprot id: A0A0M3T260
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1125411:W908 RS00920
gene id: 1125411:W908_RS00920
uniprot id: A0A0M4LGT1
names: Similarity
messages: Belongs to the arginase family.

1125411:W908 RS01400
gene id: 1125411:W908_RS01400
uniprot id: A0A0M4LFP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1125411:W908 RS00150
gene id: 1125411:W908_RS00150
uniprot id: A0A0M4LDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1125411:W908 RS01385
gene id: 1125411:W908_RS01385
uniprot id: A0A0M4LZ29
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1125411:W908 RS00320
gene id: 1125411:W908_RS00320
uniprot id: A0A0M4LYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1125411:W908 RS02470
gene id: 1125411:W908_RS02470
uniprot id: A0A0M4LEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1125411:W908 RS06755
gene id: 1125411:W908_RS06755
uniprot id: A0A0M3T264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1125411:W908 RS05205
gene id: 1125411:W908_RS05205
uniprot id: A0A0M4LPW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1125411:W908 RS08285
gene id: 1125411:W908_RS08285
uniprot id: A0A0M4LEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1125411:W908 RS01395
gene id: 1125411:W908_RS01395
uniprot id: A0A0M4L4I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1125411:W908 RS05750
gene id: 1125411:W908_RS05750
uniprot id: A0A0M4L4G9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1125411:W908 RS05950
gene id: 1125411:W908_RS05950
uniprot id: A0A0M5KRX8
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00640
gene id: 1125411:W908_RS00640
uniprot id: A0A0M5KZZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1125411:W908 RS04055
gene id: 1125411:W908_RS04055
uniprot id: A0A0M3T1Y7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS07155
gene id: 1125411:W908_RS07155
uniprot id: A0A0M3T276
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1125411:W908 RS01845
gene id: 1125411:W908_RS01845
uniprot id: A0A0M5KW07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS01445
gene id: 1125411:W908_RS01445
uniprot id: A0A0M5L035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1125411:W908 RS04425
gene id: 1125411:W908_RS04425
uniprot id: A0A0M4LDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS05095
gene id: 1125411:W908_RS05095
uniprot id: A0A0M4LGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07335
gene id: 1125411:W908_RS07335
uniprot id: A0A0M4L692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1125411:W908 RS08405
gene id: 1125411:W908_RS08405
uniprot id: A0A0M4LI00
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1125411:W908 RS08500
gene id: 1125411:W908_RS08500
uniprot id: A0A0M4LEM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1125411:W908 RS05980
gene id: 1125411:W908_RS05980
uniprot id: A0A0M4LQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS01335
gene id: 1125411:W908_RS01335
uniprot id: A0A0M4LFP1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1125411:W908 RS08340
gene id: 1125411:W908_RS08340
uniprot id: A0A0M4LGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1125411:W908 RS00255
gene id: 1125411:W908_RS00255
uniprot id: A0A0M4LYN8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1125411:W908 RS08600
gene id: 1125411:W908_RS08600
uniprot id: A0A0M4L6M5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1125411:W908 RS04940
gene id: 1125411:W908_RS04940
uniprot id: A0A0M4M085
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS04960
gene id: 1125411:W908_RS04960
uniprot id: A0A0M3T214
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1125411:W908 RS07165
gene id: 1125411:W908_RS07165
uniprot id: A0A0M4L4W7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1125411:W908 RS04885
gene id: 1125411:W908_RS04885
uniprot id: A0A0M4LGU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1125411:W908 RS02130
gene id: 1125411:W908_RS02130
uniprot id: A0A0M3T1R0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1125411:W908 RS00040
gene id: 1125411:W908_RS00040
uniprot id: A0A0M4L435
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00365
gene id: 1125411:W908_RS00365
uniprot id: A0A0M3T1L9
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1125411:W908 RS04180
gene id: 1125411:W908_RS04180
uniprot id: A0A0M4L5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1125411:W908 RS05930
gene id: 1125411:W908_RS05930
uniprot id: A0A0M4M0K1
names: Similarity
messages: Belongs to the YfgM family.

1125411:W908 RS04100
gene id: 1125411:W908_RS04100
uniprot id: A0A0M4LPJ7
names: Cofactor
messages: Can also use Mn(2+) ion.

1125411:W908 RS07045
gene id: 1125411:W908_RS07045
uniprot id: A0A0M4M3J0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1125411:W908 RS06315
gene id: 1125411:W908_RS06315
uniprot id: A0A0M3T259
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

1125411:W908 RS03050
gene id: 1125411:W908_RS03050
uniprot id: A0A0M4L500
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1125411:W908 RS00740
gene id: 1125411:W908_RS00740
uniprot id: A0A0M4M1E1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1125411:W908 RS07480
gene id: 1125411:W908_RS07480
uniprot id: A0A0M3T289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02925
gene id: 1125411:W908_RS02925
uniprot id: A0A0M5KW42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1125411:W908 RS06205
gene id: 1125411:W908_RS06205
uniprot id: A0A0M4L5X4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1125411:W908 RS06455
gene id: 1125411:W908_RS06455
uniprot id: A0A0M5KRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02985
gene id: 1125411:W908_RS02985
uniprot id: A0A0M3T1T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1125411:W908 RS04290
gene id: 1125411:W908_RS04290
uniprot id: A0A0M3T1Y2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1125411:W908 RS06410
gene id: 1125411:W908_RS06410
uniprot id: A0A0M4LDZ4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1125411:W908 RS07645
gene id: 1125411:W908_RS07645
uniprot id: A0A0M3T294
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS07560
gene id: 1125411:W908_RS07560
uniprot id: A0A0M4LED8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1125411:W908 RS02190
gene id: 1125411:W908_RS02190
uniprot id: A0A0M4L3I7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1125411:W908 RS08145
gene id: 1125411:W908_RS08145
uniprot id: A0A0M3T2G2
names: Similarity
messages: Belongs to the intimin/invasin family.

1125411:W908 RS07680
gene id: 1125411:W908_RS07680
uniprot id: A0A0M5KYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1125411:W908 RS04285
gene id: 1125411:W908_RS04285
uniprot id: A0A0M4L434
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1125411:W908 RS03820
gene id: 1125411:W908_RS03820
uniprot id: A0A0M4L3Y4
names: Similarity
messages: Belongs to the thioredoxin family.

1125411:W908 RS01135
gene id: 1125411:W908_RS01135
uniprot id: A0A0M4LFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1125411:W908 RS01170
gene id: 1125411:W908_RS01170
uniprot id: A0A0M4LNG1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1125411:W908 RS07625
gene id: 1125411:W908_RS07625
uniprot id: A0A0M4M3R7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1125411:W908 RS00750
gene id: 1125411:W908_RS00750
uniprot id: A0A0M4LC50
names: Similarity
messages: Belongs to the peptidase S51 family.

1125411:W908 RS08475
gene id: 1125411:W908_RS08475
uniprot id: A0A0M4LI08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS05180
gene id: 1125411:W908_RS05180
uniprot id: A0A0M4M2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01085
gene id: 1125411:W908_RS01085
uniprot id: A0A0M4LC88
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1125411:W908 RS02375
gene id: 1125411:W908_RS02375
uniprot id: A0A0M4LZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1125411:W908 RS01835
gene id: 1125411:W908_RS01835
uniprot id: A0A0M4L3F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS01600
gene id: 1125411:W908_RS01600
uniprot id: A0A0M3T1Q5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1125411:W908 RS02680
gene id: 1125411:W908_RS02680
uniprot id: A0A0M5KSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1125411:W908 RS01345
gene id: 1125411:W908_RS01345
uniprot id: A0A0M5KY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1125411:W908 RS02250
gene id: 1125411:W908_RS02250
uniprot id: A0A0M5KRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1125411:W908 RS01700
gene id: 1125411:W908_RS01700
uniprot id: A0A0M4LNP3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1125411:W908 RS04385
gene id: 1125411:W908_RS04385
uniprot id: A0A0M4M032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1125411:W908 RS00270
gene id: 1125411:W908_RS00270
uniprot id: A0A0M4LF82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1125411:W908 RS02400
gene id: 1125411:W908_RS02400
uniprot id: A0A0M4M1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1125411:W908 RS01480
gene id: 1125411:W908_RS01480
uniprot id: A0A0M4LEI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1125411:W908 RS01690
gene id: 1125411:W908_RS01690
uniprot id: A0A0M4LCH3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1125411:W908 RS01805
gene id: 1125411:W908_RS01805
uniprot id: A0A0M5KRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS04025
gene id: 1125411:W908_RS04025
uniprot id: A0A0M4L403
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1125411:W908 RS02595
gene id: 1125411:W908_RS02595
uniprot id: A0A0M4L4V3
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS08350
gene id: 1125411:W908_RS08350
uniprot id: A0A0M4LEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1125411:W908 RS04405
gene id: 1125411:W908_RS04405
uniprot id: A0A0M5KRS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS05075
gene id: 1125411:W908_RS05075
uniprot id: A0A0M3T218
names: Similarity
messages: Belongs to the peptidase S24 family.

1125411:W908 RS02525
gene id: 1125411:W908_RS02525
uniprot id: A0A0M4LG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1125411:W908 RS05650
gene id: 1125411:W908_RS05650
uniprot id: A0A0M4L4G0
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1125411:W908 RS07580
gene id: 1125411:W908_RS07580
uniprot id: A0A0M5KS13
names: Similarity
messages: Belongs to the P(II) protein family.

1125411:W908 RS00910
gene id: 1125411:W908_RS00910
uniprot id: A0A0M4M466
names: Similarity
messages: Belongs to the arginase family.

1125411:W908 RS07310
gene id: 1125411:W908_RS07310
uniprot id: A0A0M4L4Y3
names: Subcellular Location Annotation
messages: Cytoplasm

1125411:W908 RS04895
gene id: 1125411:W908_RS04895
uniprot id: A0A0M4M2T7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1125411:W908 RS03695
gene id: 1125411:W908_RS03695
uniprot id: A0A0M4LPE4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1125411:W908 RS05555
gene id: 1125411:W908_RS05555
uniprot id: A0A0M3T233
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS02740
gene id: 1125411:W908_RS02740
uniprot id: A0A0M4LG74
names: Similarity
messages: Belongs to the ArsC family.

1125411:W908 RS07280
gene id: 1125411:W908_RS07280
uniprot id: A0A0M4LHL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1125411:W908 RS07490
gene id: 1125411:W908_RS07490
uniprot id: A0A0M4LGB8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1125411:W908 RS04370
gene id: 1125411:W908_RS04370
uniprot id: A0A0M4LPN1
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS03110
gene id: 1125411:W908_RS03110
uniprot id: A0A0M4LZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07520
gene id: 1125411:W908_RS07520
uniprot id: A0A0M4M148
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1125411:W908 RS00285
gene id: 1125411:W908_RS00285
uniprot id: A0A0M4LE04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1125411:W908 RS00290
gene id: 1125411:W908_RS00290
uniprot id: A0A0M3T1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1125411:W908 RS08075
gene id: 1125411:W908_RS08075
uniprot id: A0A0M4LQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01590
gene id: 1125411:W908_RS01590
uniprot id: A0A0M4L4K2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1125411:W908 RS03525
gene id: 1125411:W908_RS03525
uniprot id: A0A0M4LGE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS00545
gene id: 1125411:W908_RS00545
uniprot id: A0A0M4M1B0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1125411:W908 RS00250
gene id: 1125411:W908_RS00250
uniprot id: A0A0M5KTG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06665
gene id: 1125411:W908_RS06665
uniprot id: A0A0M4LG35
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1125411:W908 RS04610
gene id: 1125411:W908_RS04610
uniprot id: A0A0M4LI96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1125411:W908 RS01705
gene id: 1125411:W908_RS01705
uniprot id: A0A0M3T1Q9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1125411:W908 RS00915
gene id: 1125411:W908_RS00915
uniprot id: A0A0M3T2F0
names: Similarity
messages: Belongs to the arginase family.

1125411:W908 RS04375
gene id: 1125411:W908_RS04375
uniprot id: A0A0M3T1Z9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1125411:W908 RS02370
gene id: 1125411:W908_RS02370
uniprot id: A0A0M5KTM6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1125411:W908 RS06165
gene id: 1125411:W908_RS06165
uniprot id: A0A0M4LFY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1125411:W908 RS07835
gene id: 1125411:W908_RS07835
uniprot id: A0A0M4M182
names: Similarity
messages: Belongs to the UPF0111 family.

1125411:W908 RS03960
gene id: 1125411:W908_RS03960
uniprot id: A0A0M4LD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS05050
gene id: 1125411:W908_RS05050
uniprot id: A0A0M4LDI3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1125411:W908 RS07930
gene id: 1125411:W908_RS07930
uniprot id: A0A0M4LGH5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1125411:W908 RS06295
gene id: 1125411:W908_RS06295
uniprot id: A0A0M3T248
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1125411:W908 RS03910
gene id: 1125411:W908_RS03910
uniprot id: A0A0M4LZW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1125411:W908 RS06305
gene id: 1125411:W908_RS06305
uniprot id: A0A0M4LFZ7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1125411:W908 RS03160
gene id: 1125411:W908_RS03160
uniprot id: A0A0M4LCY0
names: Similarity
messages: Belongs to the proline racemase family.

1125411:W908 RS08040
gene id: 1125411:W908_RS08040
uniprot id: A0A0M5KYS8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1125411:W908 RS07220
gene id: 1125411:W908_RS07220
uniprot id: A0A0M3T278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS04360
gene id: 1125411:W908_RS04360
uniprot id: A0A0M4LDB4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1125411:W908 RS08590
gene id: 1125411:W908_RS08590
uniprot id: A0A0M3T2E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1125411:W908 RS04850
gene id: 1125411:W908_RS04850
uniprot id: A0A0M4M076
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1125411:W908 RS01160
gene id: 1125411:W908_RS01160
uniprot id: A0A0M4LC95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS08330
gene id: 1125411:W908_RS08330
uniprot id: A0A0M5KS36
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1125411:W908 RS04935
gene id: 1125411:W908_RS04935
uniprot id: A0A0M4M4E0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1125411:W908 RS07745
gene id: 1125411:W908_RS07745
uniprot id: A0A0M4L534
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1125411:W908 RS01370
gene id: 1125411:W908_RS01370
uniprot id: A0A0M3T1M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1125411:W908 RS02165
gene id: 1125411:W908_RS02165
uniprot id: A0A0M5KRL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1125411:W908 RS02875
gene id: 1125411:W908_RS02875
uniprot id: A0A0M4LG88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02045
gene id: 1125411:W908_RS02045
uniprot id: A0A0M4L3H2
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1125411:W908 RS01675
gene id: 1125411:W908_RS01675
uniprot id: A0A0M4M1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1125411:W908 RS00600
gene id: 1125411:W908_RS00600
uniprot id: A0A0M5KY80
names: Similarity
messages: Belongs to the oxoprolinase family.

1125411:W908 RS01150
gene id: 1125411:W908_RS01150
uniprot id: A0A0M4LEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1125411:W908 RS04855
gene id: 1125411:W908_RS04855
uniprot id: A0A0M4L5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1125411:W908 RS01235
gene id: 1125411:W908_RS01235
uniprot id: A0A0M4LNH7
names: Similarity
messages: Belongs to the UPF0260 family.

1125411:W908 RS03535
gene id: 1125411:W908_RS03535
uniprot id: A0A0M5KSX8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1125411:W908 RS02735
gene id: 1125411:W908_RS02735
uniprot id: A0A0M4L4W8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS07060
gene id: 1125411:W908_RS07060
uniprot id: A0A0M4LE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1125411:W908 RS03390
gene id: 1125411:W908_RS03390
uniprot id: A0A0M4LPB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS03650
gene id: 1125411:W908_RS03650
uniprot id: A0A0M4L557
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS02135
gene id: 1125411:W908_RS02135
uniprot id: A0A0M4LZC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1125411:W908 RS01660
gene id: 1125411:W908_RS01660
uniprot id: A0A0M4L4L0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1125411:W908 RS05170
gene id: 1125411:W908_RS05170
uniprot id: A0A0M4LGX2
names: Similarity
messages: Belongs to the IlvD/Edd family.

1125411:W908 RS03950
gene id: 1125411:W908_RS03950
uniprot id: A0A0M3T1Y3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1125411:W908 RS00155
gene id: 1125411:W908_RS00155
uniprot id: A0A0M4LBX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1125411:W908 RS07665
gene id: 1125411:W908_RS07665
uniprot id: A0A0M3T2B2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1125411:W908 RS04915
gene id: 1125411:W908_RS04915
uniprot id: A0A0M4L482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1125411:W908 RS03815
gene id: 1125411:W908_RS03815
uniprot id: A0A0M4LD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS05385
gene id: 1125411:W908_RS05385
uniprot id: A0A0M3T217
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1125411:W908 RS02315
gene id: 1125411:W908_RS02315
uniprot id: A0A0M5KSV3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1125411:W908 RS05945
gene id: 1125411:W908_RS05945
uniprot id: A0A0M4LH71
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS07955
gene id: 1125411:W908_RS07955
uniprot id: A0A0M5KS25
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1125411:W908 RS02340
gene id: 1125411:W908_RS02340
uniprot id: A0A0M4LES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02120
gene id: 1125411:W908_RS02120
uniprot id: A0A0M4LNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1125411:W908 RS00020
gene id: 1125411:W908_RS00020
uniprot id: A0A0M3T1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1125411:W908 RS02475
gene id: 1125411:W908_RS02475
uniprot id: A0A0M4LCQ7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1125411:W908 RS04060
gene id: 1125411:W908_RS04060
uniprot id: A0A0M4L5B0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS03655
gene id: 1125411:W908_RS03655
uniprot id: A0A0M3T1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01960
gene id: 1125411:W908_RS01960
uniprot id: A0A0M3T1Q4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1125411:W908 RS06450
gene id: 1125411:W908_RS06450
uniprot id: A0A0M3T263
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.

1125411:W908 RS03860
gene id: 1125411:W908_RS03860
uniprot id: A0A0M3T1W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1125411:W908 RS03040
gene id: 1125411:W908_RS03040
uniprot id: A0A0M3T1U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1125411:W908 RS07370
gene id: 1125411:W908_RS07370
uniprot id: A0A0M4L4Z0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1125411:W908 RS08645
gene id: 1125411:W908_RS08645
uniprot id: A0A0M3T2E6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1125411:W908 RS02195
gene id: 1125411:W908_RS02195
uniprot id: A0A0M3T1R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1125411:W908 RS01360
gene id: 1125411:W908_RS01360
uniprot id: A0A0M4LCD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1125411:W908 RS02715
gene id: 1125411:W908_RS02715
uniprot id: A0A0M4LP16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1125411:W908 RS02090
gene id: 1125411:W908_RS02090
uniprot id: A0A0M5KRM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1125411:W908 RS06555
gene id: 1125411:W908_RS06555
uniprot id: A0A0M3T267
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS05325
gene id: 1125411:W908_RS05325
uniprot id: A0A0M4LFQ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS03105
gene id: 1125411:W908_RS03105
uniprot id: A0A0M5KTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS08580
gene id: 1125411:W908_RS08580
uniprot id: A0A0M5L0N4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1125411:W908 RS03745
gene id: 1125411:W908_RS03745
uniprot id: A0A0M4LF83
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS02125
gene id: 1125411:W908_RS02125
uniprot id: A0A0M5L061
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS01890
gene id: 1125411:W908_RS01890
uniprot id: A0A0M4M1T7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1125411:W908 RS06285
gene id: 1125411:W908_RS06285
uniprot id: A0A0M4LHB3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1125411:W908 RS04140
gene id: 1125411:W908_RS04140
uniprot id: A0A0M4M2K5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1125411:W908 RS00580
gene id: 1125411:W908_RS00580
uniprot id: A0A0M5KTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1125411:W908 RS02990
gene id: 1125411:W908_RS02990
uniprot id: A0A0M4LG93
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1125411:W908 RS04175
gene id: 1125411:W908_RS04175
uniprot id: A0A0M4M009
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1125411:W908 RS04785
gene id: 1125411:W908_RS04785
uniprot id: A0A0M4LFK3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1125411:W908 RS04130
gene id: 1125411:W908_RS04130
uniprot id: A0A0M5KRS0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1125411:W908 RS06060
gene id: 1125411:W908_RS06060
uniprot id: A0A0M5KWC1
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1125411:W908 RS01355
gene id: 1125411:W908_RS01355
uniprot id: A0A0M4LEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1125411:W908 RS02485
gene id: 1125411:W908_RS02485
uniprot id: A0A0M4L3L8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS02720
gene id: 1125411:W908_RS02720
uniprot id: A0A0M5KTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1125411:W908 RS01050
gene id: 1125411:W908_RS01050
uniprot id: A0A0M3T1N9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1125411:W908 RS00195
gene id: 1125411:W908_RS00195
uniprot id: A0A0M4LF72
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1125411:W908 RS08550
gene id: 1125411:W908_RS08550
uniprot id: A0A0M4M429
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00650
gene id: 1125411:W908_RS00650
uniprot id: A0A0M4L4A0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06300
gene id: 1125411:W908_RS06300
uniprot id: A0A0M4M396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1125411:W908 RS03020
gene id: 1125411:W908_RS03020
uniprot id: A0A0M4LCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1125411:W908 RS00685
gene id: 1125411:W908_RS00685
uniprot id: A0A0M4LE61
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS00665
gene id: 1125411:W908_RS00665
uniprot id: A0A0M5KRI8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS08310
gene id: 1125411:W908_RS08310
uniprot id: A0A0M4M1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1125411:W908 RS00720
gene id: 1125411:W908_RS00720
uniprot id: A0A0M4L4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1125411:W908 RS04740
gene id: 1125411:W908_RS04740
uniprot id: A0A0M3T208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1125411:W908 RS04090
gene id: 1125411:W908_RS04090
uniprot id: A0A0M4LD80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1125411:W908 RS04625
gene id: 1125411:W908_RS04625
uniprot id: A0A0M4LGR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1125411:W908 RS02380
gene id: 1125411:W908_RS02380
uniprot id: A0A0M4L4T1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1125411:W908 RS05435
gene id: 1125411:W908_RS05435
uniprot id: A0A0M5KTV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS03350
gene id: 1125411:W908_RS03350
uniprot id: A0A0M4LGD5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS02445
gene id: 1125411:W908_RS02445
uniprot id: A0A0M4L4U1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1125411:W908 RS04390
gene id: 1125411:W908_RS04390
uniprot id: A0A0M4L5K1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1125411:W908 RS02270
gene id: 1125411:W908_RS02270
uniprot id: A0A0M4LCN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1125411:W908 RS05005
gene id: 1125411:W908_RS05005
uniprot id: A0A0M4M096
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01215
gene id: 1125411:W908_RS01215
uniprot id: A0A0M4LED1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1125411:W908 RS07550
gene id: 1125411:W908_RS07550
uniprot id: A0A0M3T2A8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1125411:W908 RS02710
gene id: 1125411:W908_RS02710
uniprot id: A0A0M4LR77
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1125411:W908 RS06345
gene id: 1125411:W908_RS06345
uniprot id: A0A0M4LQA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1125411:W908 RS05800
gene id: 1125411:W908_RS05800
uniprot id: A0A0M4M338
names: Similarity
messages: Belongs to the RecJ family.

1125411:W908 RS07450
gene id: 1125411:W908_RS07450
uniprot id: A0A0M3T2A4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1125411:W908 RS05760
gene id: 1125411:W908_RS05760
uniprot id: A0A0M5KRW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1125411:W908 RS06715
gene id: 1125411:W908_RS06715
uniprot id: A0A0M4L634
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS03640
gene id: 1125411:W908_RS03640
uniprot id: A0A0M5L073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS07365
gene id: 1125411:W908_RS07365
uniprot id: A0A0M4LEB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1125411:W908 RS01350
gene id: 1125411:W908_RS01350
uniprot id: A0A0M4M1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1125411:W908 RS02390
gene id: 1125411:W908_RS02390
uniprot id: A0A0M4LG45
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1125411:W908 RS01380
gene id: 1125411:W908_RS01380
uniprot id: A0A0M5L010
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1125411:W908 RS00560
gene id: 1125411:W908_RS00560
uniprot id: A0A0M4LC24
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS00370
gene id: 1125411:W908_RS00370
uniprot id: A0A0M4L2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS02415
gene id: 1125411:W908_RS02415
uniprot id: A0A0M4LCP8
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1125411:W908 RS03780
gene id: 1125411:W908_RS03780
uniprot id: A0A0M3T1X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS08420
gene id: 1125411:W908_RS08420
uniprot id: A0A0M4M407
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1125411:W908 RS04095
gene id: 1125411:W908_RS04095
uniprot id: A0A0M4L410
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1125411:W908 RS02285
gene id: 1125411:W908_RS02285
uniprot id: A0A0M4LNW4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1125411:W908 RS07375
gene id: 1125411:W908_RS07375
uniprot id: A0A0M3T285
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1125411:W908 RS06460
gene id: 1125411:W908_RS06460
uniprot id: A0A0M4M3B6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01055
gene id: 1125411:W908_RS01055
uniprot id: A0A0M5KRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1125411:W908 RS05685
gene id: 1125411:W908_RS05685
uniprot id: A0A0M4LH22
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS03750
gene id: 1125411:W908_RS03750
uniprot id: A0A0M4LD39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1125411:W908 RS04910
gene id: 1125411:W908_RS04910
uniprot id: A0A0M4LDG5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1125411:W908 RS05900
gene id: 1125411:W908_RS05900
uniprot id: A0A0M4LDS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1125411:W908 RS04410
gene id: 1125411:W908_RS04410
uniprot id: A0A0M3T1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1125411:W908 RS02850
gene id: 1125411:W908_RS02850
uniprot id: A0A0M3T1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1125411:W908 RS04905
gene id: 1125411:W908_RS04905
uniprot id: A0A0M4LFL2
names: Similarity
messages: Belongs to the HesB/IscA family.

1125411:W908 RS06825
gene id: 1125411:W908_RS06825
uniprot id: A0A0M3T277
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS02520
gene id: 1125411:W908_RS02520
uniprot id: A0A0M4L4U7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1125411:W908 RS07390
gene id: 1125411:W908_RS07390
uniprot id: A0A0M4M130
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS02420
gene id: 1125411:W908_RS02420
uniprot id: A0A0M4L3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS02430
gene id: 1125411:W908_RS02430
uniprot id: A0A0M5L043
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1125411:W908 RS08035
gene id: 1125411:W908_RS08035
uniprot id: A0A0M4LHW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1125411:W908 RS05975
gene id: 1125411:W908_RS05975
uniprot id: A0A0M4L4I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02695
gene id: 1125411:W908_RS02695
uniprot id: A0A0M4LEZ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1125411:W908 RS01990
gene id: 1125411:W908_RS01990
uniprot id: A0A0M4LZA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS03065
gene id: 1125411:W908_RS03065
uniprot id: A0A0M5KSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1125411:W908 RS04395
gene id: 1125411:W908_RS04395
uniprot id: A0A0M4L5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1125411:W908 RS06290
gene id: 1125411:W908_RS06290
uniprot id: A0A0M5KRZ0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1125411:W908 RS03995
gene id: 1125411:W908_RS03995
uniprot id: A0A0M4LGK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02235
gene id: 1125411:W908_RS02235
uniprot id: A0A0M3T1S6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1125411:W908 RS06200
gene id: 1125411:W908_RS06200
uniprot id: A0A0M3T255
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1125411:W908 RS00345
gene id: 1125411:W908_RS00345
uniprot id: A0A0M4M184
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1125411:W908 RS02805
gene id: 1125411:W908_RS02805
uniprot id: A0A0M4LG81
names: Similarity
messages: Belongs to the asparagine synthetase family.

1125411:W908 RS06465
gene id: 1125411:W908_RS06465
uniprot id: A0A0M4LG10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1125411:W908 RS07505
gene id: 1125411:W908_RS07505
uniprot id: A0A0M4L503
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1125411:W908 RS02450
gene id: 1125411:W908_RS02450
uniprot id: A0A0M4LG52
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS01830
gene id: 1125411:W908_RS01830
uniprot id: A0A0M4LCI7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1125411:W908 RS00215
gene id: 1125411:W908_RS00215
uniprot id: A0A0M4LDZ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS08570
gene id: 1125411:W908_RS08570
uniprot id: A0A0M3T2B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1125411:W908 RS01510
gene id: 1125411:W908_RS01510
uniprot id: A0A0M4LZ47
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1125411:W908 RS08095
gene id: 1125411:W908_RS08095
uniprot id: A0A0M3T2A3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1125411:W908 RS01000
gene id: 1125411:W908_RS01000
uniprot id: A0A0M4LE96
names: Similarity
messages: Belongs to the TPP enzyme family.

1125411:W908 RS04320
gene id: 1125411:W908_RS04320
uniprot id: A0A0M3T1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS07380
gene id: 1125411:W908_RS07380
uniprot id: A0A0M4LQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1125411:W908 RS01680
gene id: 1125411:W908_RS01680
uniprot id: A0A0M4LEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1125411:W908 RS07675
gene id: 1125411:W908_RS07675
uniprot id: A0A0M4LHS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1125411:W908 RS01635
gene id: 1125411:W908_RS01635
uniprot id: A0A0M5KYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS00170
gene id: 1125411:W908_RS00170
uniprot id: A0A0M4LN35
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1125411:W908 RS07180
gene id: 1125411:W908_RS07180
uniprot id: A0A0M4LQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1125411:W908 RS05660
gene id: 1125411:W908_RS05660
uniprot id: A0A0M3T237
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1125411:W908 RS07935
gene id: 1125411:W908_RS07935
uniprot id: A0A0M4LEH1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1125411:W908 RS00340
gene id: 1125411:W908_RS00340
uniprot id: A0A0M3T1I9
names: Similarity
messages: Belongs to the TrpF family.

1125411:W908 RS03955
gene id: 1125411:W908_RS03955
uniprot id: A0A0M4LFA5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1125411:W908 RS03490
gene id: 1125411:W908_RS03490
uniprot id: A0A0M4L3V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1125411:W908 RS00465
gene id: 1125411:W908_RS00465
uniprot id: A0A0M3T1M2
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1125411:W908 RS05390
gene id: 1125411:W908_RS05390
uniprot id: A0A0M4M301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1125411:W908 RS03355
gene id: 1125411:W908_RS03355
uniprot id: A0A0M5KRP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1125411:W908 RS00455
gene id: 1125411:W908_RS00455
uniprot id: A0A0M4L480
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1125411:W908 RS05340
gene id: 1125411:W908_RS05340
uniprot id: A0A0M4L4D6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1125411:W908 RS05230
gene id: 1125411:W908_RS05230
uniprot id: A0A0M4LGX9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS02545
gene id: 1125411:W908_RS02545
uniprot id: A0A0M3T1S5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1125411:W908 RS01530
gene id: 1125411:W908_RS01530
uniprot id: A0A0M4LFR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1125411:W908 RS07945
gene id: 1125411:W908_RS07945
uniprot id: A0A0M3T299
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1125411:W908 RS02035
gene id: 1125411:W908_RS02035
uniprot id: A0A0M4LCL1
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS01465
gene id: 1125411:W908_RS01465
uniprot id: A0A0M5KRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1125411:W908 RS04215
gene id: 1125411:W908_RS04215
uniprot id: A0A0M4LFE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS05025
gene id: 1125411:W908_RS05025
uniprot id: A0A0M5KT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01115
gene id: 1125411:W908_RS01115
uniprot id: A0A0M5L020
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS07810
gene id: 1125411:W908_RS07810
uniprot id: A0A0M4LEF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1125411:W908 RS00575
gene id: 1125411:W908_RS00575
uniprot id: A0A0M3T1M6
names: Subcellular Location Annotation
messages: Cytoplasm

1125411:W908 RS06570
gene id: 1125411:W908_RS06570
uniprot id: A0A0M4L619
names: Similarity
messages: Belongs to the YciI family.

1125411:W908 RS05615
gene id: 1125411:W908_RS05615
uniprot id: A0A0M4LH13
names: Similarity
messages: Belongs to the glutamate synthase family.

1125411:W908 RS01175
gene id: 1125411:W908_RS01175
uniprot id: A0A0M3T1P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02015
gene id: 1125411:W908_RS02015
uniprot id: A0A0M3T1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1125411:W908 RS01970
gene id: 1125411:W908_RS01970
uniprot id: A0A0M4L3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS05860
gene id: 1125411:W908_RS05860
uniprot id: A0A0M3T231
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1125411:W908 RS02660
gene id: 1125411:W908_RS02660
uniprot id: A0A0M4LZI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1125411:W908 RS02460
gene id: 1125411:W908_RS02460
uniprot id: A0A0M5KRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS06585
gene id: 1125411:W908_RS06585
uniprot id: A0A0M3T258
names: Similarity
messages: Belongs to the TrpC family.

1125411:W908 RS05360
gene id: 1125411:W908_RS05360
uniprot id: A0A0M4M0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02745
gene id: 1125411:W908_RS02745
uniprot id: A0A0M3T1U5
names: Similarity
messages: Belongs to the thioredoxin family.

1125411:W908 RS05090
gene id: 1125411:W908_RS05090
uniprot id: A0A0M4L5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07830
gene id: 1125411:W908_RS07830
uniprot id: A0A0M5L0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1125411:W908 RS00480
gene id: 1125411:W908_RS00480
uniprot id: A0A0M4L5F3
names: Similarity
messages: Belongs to the aldose epimerase family.

1125411:W908 RS06195
gene id: 1125411:W908_RS06195
uniprot id: A0A0M4M0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02575
gene id: 1125411:W908_RS02575
uniprot id: A0A0M3T1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1125411:W908 RS03980
gene id: 1125411:W908_RS03980
uniprot id: A0A0M3T1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1125411:W908 RS03025
gene id: 1125411:W908_RS03025
uniprot id: A0A0M4L3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1125411:W908 RS04330
gene id: 1125411:W908_RS04330
uniprot id: A0A0M4LGP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS07660
gene id: 1125411:W908_RS07660
uniprot id: A0A0M4M165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1125411:W908 RS06125
gene id: 1125411:W908_RS06125
uniprot id: A0A0M5KRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1125411:W908 RS06325
gene id: 1125411:W908_RS06325
uniprot id: A0A0M4L4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Nucleus

1125411:W908 RS04190
gene id: 1125411:W908_RS04190
uniprot id: A0A0M4LGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1125411:W908 RS00765
gene id: 1125411:W908_RS00765
uniprot id: A0A0M3T1K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1125411:W908 RS00780
gene id: 1125411:W908_RS00780
uniprot id: A0A0M5KVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1125411:W908 RS00890
gene id: 1125411:W908_RS00890
uniprot id: A0A0M5KSR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1125411:W908 RS01490
gene id: 1125411:W908_RS01490
uniprot id: A0A0M3T1Q1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1125411:W908 RS05500
gene id: 1125411:W908_RS05500
uniprot id: A0A0M4LQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1125411:W908 RS07615
gene id: 1125411:W908_RS07615
uniprot id: A0A0M4L5Q8
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS02255
gene id: 1125411:W908_RS02255
uniprot id: A0A0M4M1X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1125411:W908 RS00850
gene id: 1125411:W908_RS00850
uniprot id: A0A0M3T1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1125411:W908 RS08530
gene id: 1125411:W908_RS08530
uniprot id: A0A0M4L6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1125411:W908 RS01425
gene id: 1125411:W908_RS01425
uniprot id: A0A0M4LCD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1125411:W908 RS07495
gene id: 1125411:W908_RS07495
uniprot id: A0A0M4LED0
names: Similarity
messages: Belongs to the peptidase U62 family.

1125411:W908 RS00500
gene id: 1125411:W908_RS00500
uniprot id: A0A0M4L2Z3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS02790
gene id: 1125411:W908_RS02790
uniprot id: A0A0M4LZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1125411:W908 RS00310
gene id: 1125411:W908_RS00310
uniprot id: A0A0M3T1L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1125411:W908 RS03225
gene id: 1125411:W908_RS03225
uniprot id: A0A0M4LI62
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS00825
gene id: 1125411:W908_RS00825
uniprot id: A0A0M4M1K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1125411:W908 RS01195
gene id: 1125411:W908_RS01195
uniprot id: A0A0M4LFM6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1125411:W908 RS01245
gene id: 1125411:W908_RS01245
uniprot id: A0A0M4LZ11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1125411:W908 RS05225
gene id: 1125411:W908_RS05225
uniprot id: A0A0M4L5M0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS02455
gene id: 1125411:W908_RS02455
uniprot id: A0A0M3T1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS00520
gene id: 1125411:W908_RS00520
uniprot id: A0A0M4LYR8
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1125411:W908 RS00770
gene id: 1125411:W908_RS00770
uniprot id: A0A0M4LNB7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1125411:W908 RS07095
gene id: 1125411:W908_RS07095
uniprot id: A0A0M4LQJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1125411:W908 RS01280
gene id: 1125411:W908_RS01280
uniprot id: A0A0M4LEG6
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1125411:W908 RS05195
gene id: 1125411:W908_RS05195
uniprot id: A0A0M4LDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1125411:W908 RS03760
gene id: 1125411:W908_RS03760
uniprot id: A0A0M3T1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1125411:W908 RS01745
gene id: 1125411:W908_RS01745
uniprot id: A0A0M4LEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1125411:W908 RS03590
gene id: 1125411:W908_RS03590
uniprot id: A0A0M4L552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1125411:W908 RS00815
gene id: 1125411:W908_RS00815
uniprot id: A0A0M4LE81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1125411:W908 RS01295
gene id: 1125411:W908_RS01295
uniprot id: A0A0M4LNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1125411:W908 RS00790
gene id: 1125411:W908_RS00790
uniprot id: A0A0M3T1N3
names: Similarity
messages: Belongs to the peptidase M24B family.

1125411:W908 RS00175
gene id: 1125411:W908_RS00175
uniprot id: A0A0M5KRF8
names: Similarity
messages: Belongs to the citrate synthase family.

1125411:W908 RS03045
gene id: 1125411:W908_RS03045
uniprot id: A0A0M4LZM7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1125411:W908 RS05895
gene id: 1125411:W908_RS05895
uniprot id: A0A0M4LFU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1125411:W908 RS06190
gene id: 1125411:W908_RS06190
uniprot id: A0A0M5KTX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS04050
gene id: 1125411:W908_RS04050
uniprot id: A0A0M5KYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS06170
gene id: 1125411:W908_RS06170
uniprot id: A0A0M4LDW1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1125411:W908 RS04890
gene id: 1125411:W908_RS04890
uniprot id: A0A0M5KRU1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1125411:W908 RS01980
gene id: 1125411:W908_RS01980
uniprot id: A0A0M3T1R8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1125411:W908 RS07770
gene id: 1125411:W908_RS07770
uniprot id: A0A0M4L6D9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1125411:W908 RS06995
gene id: 1125411:W908_RS06995
uniprot id: A0A0M4LQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS06490
gene id: 1125411:W908_RS06490
uniprot id: A0A0M5KRY3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1125411:W908 RS01780
gene id: 1125411:W908_RS01780
uniprot id: A0A0M4LZ81
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1125411:W908 RS07435
gene id: 1125411:W908_RS07435
uniprot id: A0A0M4LEB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1125411:W908 RS02320
gene id: 1125411:W908_RS02320
uniprot id: A0A0M3T1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1125411:W908 RS04040
gene id: 1125411:W908_RS04040
uniprot id: A0A0M5L0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS03145
gene id: 1125411:W908_RS03145
uniprot id: A0A0M4LF30
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1125411:W908 RS08640
gene id: 1125411:W908_RS08640
uniprot id: A0A0M4LR35
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1125411:W908 RS03875
gene id: 1125411:W908_RS03875
uniprot id: A0A0M4LD56
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1125411:W908 RS05185
gene id: 1125411:W908_RS05185
uniprot id: A0A0M3T222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07815
gene id: 1125411:W908_RS07815
uniprot id: A0A0M3T2B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS08290
gene id: 1125411:W908_RS08290
uniprot id: A0A0M4L5A0
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS07620
gene id: 1125411:W908_RS07620
uniprot id: A0A0M5KT88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1125411:W908 RS05870
gene id: 1125411:W908_RS05870
uniprot id: A0A0M4L5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1125411:W908 RS07445
gene id: 1125411:W908_RS07445
uniprot id: A0A0M4LQP1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1125411:W908 RS07530
gene id: 1125411:W908_RS07530
uniprot id: A0A0M3T291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS08380
gene id: 1125411:W908_RS08380
uniprot id: A0A0M4M1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1125411:W908 RS05495
gene id: 1125411:W908_RS05495
uniprot id: A0A0M4L4E7
names: Similarity
messages: Belongs to the Gfa family.

1125411:W908 RS07975
gene id: 1125411:W908_RS07975
uniprot id: A0A0M4LHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1125411:W908 RS05175
gene id: 1125411:W908_RS05175
uniprot id: A0A0M5KRV8
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1125411:W908 RS08370
gene id: 1125411:W908_RS08370
uniprot id: A0A0M3T2D3
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1125411:W908 RS00325
gene id: 1125411:W908_RS00325
uniprot id: A0A0M4L464
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1125411:W908 RS02620
gene id: 1125411:W908_RS02620
uniprot id: A0A0M4LEY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS07215
gene id: 1125411:W908_RS07215
uniprot id: A0A0M5KS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07160
gene id: 1125411:W908_RS07160
uniprot id: A0A0M4LE84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1125411:W908 RS03135
gene id: 1125411:W908_RS03135
uniprot id: A0A0M4M288
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1125411:W908 RS07315
gene id: 1125411:W908_RS07315
uniprot id: A0A0M4LQM3
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1125411:W908 RS05315
gene id: 1125411:W908_RS05315
uniprot id: A0A0M5KRV3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1125411:W908 RS07415
gene id: 1125411:W908_RS07415
uniprot id: A0A0M5KS21
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1125411:W908 RS05260
gene id: 1125411:W908_RS05260
uniprot id: A0A0M4LFQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1125411:W908 RS04400
gene id: 1125411:W908_RS04400
uniprot id: A0A0M4LGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1125411:W908 RS03470
gene id: 1125411:W908_RS03470
uniprot id: A0A0M5KRP7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1125411:W908 RS06495
gene id: 1125411:W908_RS06495
uniprot id: A0A0M4M0S5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1125411:W908 RS03030
gene id: 1125411:W908_RS03030
uniprot id: A0A0M4LP67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1125411:W908 RS02080
gene id: 1125411:W908_RS02080
uniprot id: A0A0M3T1Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1125411:W908 RS04640
gene id: 1125411:W908_RS04640
uniprot id: A0A0M4M2Q5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1125411:W908 RS03620
gene id: 1125411:W908_RS03620
uniprot id: A0A0M4LD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS03985
gene id: 1125411:W908_RS03985
uniprot id: A0A0M4LZX7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1125411:W908 RS08575
gene id: 1125411:W908_RS08575
uniprot id: A0A0M4LR27
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1125411:W908 RS03560
gene id: 1125411:W908_RS03560
uniprot id: A0A0M4L3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1125411:W908 RS04195
gene id: 1125411:W908_RS04195
uniprot id: A0A0M5KT02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1125411:W908 RS06500
gene id: 1125411:W908_RS06500
uniprot id: A0A0M3T265
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1125411:W908 RS08430
gene id: 1125411:W908_RS08430
uniprot id: A0A0M4LEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS01625
gene id: 1125411:W908_RS01625
uniprot id: A0A0M4L3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS03890
gene id: 1125411:W908_RS03890
uniprot id: A0A0M3T2G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1125411:W908 RS03250
gene id: 1125411:W908_RS03250
uniprot id: A0A0M4LEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1125411:W908 RS03140
gene id: 1125411:W908_RS03140
uniprot id: A0A0M4L5H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1125411:W908 RS07805
gene id: 1125411:W908_RS07805
uniprot id: A0A0M4LGF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1125411:W908 RS01640
gene id: 1125411:W908_RS01640
uniprot id: A0A0M4LNN4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1125411:W908 RS00185
gene id: 1125411:W908_RS00185
uniprot id: A0A0M4LYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1125411:W908 RS08460
gene id: 1125411:W908_RS08460
uniprot id: A0A0M4L6K9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1125411:W908 RS06380
gene id: 1125411:W908_RS06380
uniprot id: A0A0M3T250
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1125411:W908 RS06015
gene id: 1125411:W908_RS06015
uniprot id: A0A0M3T238
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1125411:W908 RS01460
gene id: 1125411:W908_RS01460
uniprot id: A0A0M4LFQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1125411:W908 RS02310
gene id: 1125411:W908_RS02310
uniprot id: A0A0M4LG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1125411:W908 RS06855
gene id: 1125411:W908_RS06855
uniprot id: A0A0M4LHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1125411:W908 RS06085
gene id: 1125411:W908_RS06085
uniprot id: A0A0M5KRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS06735
gene id: 1125411:W908_RS06735
uniprot id: A0A0M4M3F3
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS02580
gene id: 1125411:W908_RS02580
uniprot id: A0A0M5KW34
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Homotrimer.

1125411:W908 RS05520
gene id: 1125411:W908_RS05520
uniprot id: A0A0M4M0F8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1125411:W908 RS06610
gene id: 1125411:W908_RS06610
uniprot id: A0A0M3T269
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1125411:W908 RS07100
gene id: 1125411:W908_RS07100
uniprot id: A0A0M5L0J1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1125411:W908 RS05510
gene id: 1125411:W908_RS05510
uniprot id: A0A0M3T221
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1125411:W908 RS07000
gene id: 1125411:W908_RS07000
uniprot id: A0A0M5L0G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1125411:W908 RS07535
gene id: 1125411:W908_RS07535
uniprot id: A0A0M4LHQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS04350
gene id: 1125411:W908_RS04350
uniprot id: A0A0M4LFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1125411:W908 RS02110
gene id: 1125411:W908_RS02110
uniprot id: A0A0M4LCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1125411:W908 RS03625
gene id: 1125411:W908_RS03625
uniprot id: A0A0M3T1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS07880
gene id: 1125411:W908_RS07880
uniprot id: A0A0M4L555
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1125411:W908 RS03480
gene id: 1125411:W908_RS03480
uniprot id: A0A0M4LF51
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1125411:W908 RS07120
gene id: 1125411:W908_RS07120
uniprot id: A0A0M4L670
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1125411:W908 RS08650
gene id: 1125411:W908_RS08650
uniprot id: A0A0M4LIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1125411:W908 RS08490
gene id: 1125411:W908_RS08490
uniprot id: A0A0M3T2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1125411:W908 RS00265
gene id: 1125411:W908_RS00265
uniprot id: A0A0M4L458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1125411:W908 RS00625
gene id: 1125411:W908_RS00625
uniprot id: A0A0M3T1M8
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS08180
gene id: 1125411:W908_RS08180
uniprot id: A0A0M5L0M3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

1125411:W908 RS07105
gene id: 1125411:W908_RS07105
uniprot id: A0A0M4L6X6
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1125411:W908 RS01330
gene id: 1125411:W908_RS01330
uniprot id: A0A0M4L4H8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1125411:W908 RS07285
gene id: 1125411:W908_RS07285
uniprot id: A0A0M5KT78
names: PTM
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1125411:W908 RS04315
gene id: 1125411:W908_RS04315
uniprot id: A0A0M4M023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS00180
gene id: 1125411:W908_RS00180
uniprot id: A0A0M3T1I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1125411:W908 RS04110
gene id: 1125411:W908_RS04110
uniprot id: A0A0M5KW70
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1125411:W908 RS03545
gene id: 1125411:W908_RS03545
uniprot id: A0A0M4LF59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1125411:W908 RS07275
gene id: 1125411:W908_RS07275
uniprot id: A0A0M3T280
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1125411:W908 RS06395
gene id: 1125411:W908_RS06395
uniprot id: A0A0M4M3A6
names: Similarity
messages: Belongs to the ArsC family.

1125411:W908 RS02070
gene id: 1125411:W908_RS02070
uniprot id: A0A0M4L4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS03645
gene id: 1125411:W908_RS03645
uniprot id: A0A0M4LZT4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1125411:W908 RS05305
gene id: 1125411:W908_RS05305
uniprot id: A0A0M4L5M8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS03785
gene id: 1125411:W908_RS03785
uniprot id: A0A0M4L579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS00900
gene id: 1125411:W908_RS00900
uniprot id: A0A0M4M1G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS00330
gene id: 1125411:W908_RS00330
uniprot id: A0A0M4LF90
names: Similarity
messages: Belongs to the Smg family.

1125411:W908 RS01520
gene id: 1125411:W908_RS01520
uniprot id: A0A0M4L4J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1125411:W908 RS07230
gene id: 1125411:W908_RS07230
uniprot id: A0A0M4M3L2
names: Similarity
messages: Belongs to the RutC family.

1125411:W908 RS01735
gene id: 1125411:W908_RS01735
uniprot id: A0A0M3T1P6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1125411:W908 RS02880
gene id: 1125411:W908_RS02880
uniprot id: A0A0M5KRN4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1125411:W908 RS07865
gene id: 1125411:W908_RS07865
uniprot id: A0A0M3T2B8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1125411:W908 RS03515
gene id: 1125411:W908_RS03515
uniprot id: A0A0M3T1W7
names: Similarity
messages: Belongs to the peptidase M1 family.

1125411:W908 RS01940
gene id: 1125411:W908_RS01940
uniprot id: A0A0M4LFX1
names: Similarity
messages: Belongs to the glutamate synthase family.

1125411:W908 RS08410
gene id: 1125411:W908_RS08410
uniprot id: A0A0M5KTA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1125411:W908 RS02325
gene id: 1125411:W908_RS02325
uniprot id: A0A0M4M1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1125411:W908 RS07135
gene id: 1125411:W908_RS07135
uniprot id: A0A0M5KS02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1125411:W908 RS00955
gene id: 1125411:W908_RS00955
uniprot id: A0A0M5KTI3
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1125411:W908 RS06220
gene id: 1125411:W908_RS06220
uniprot id: A0A0M4M388
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1125411:W908 RS07950
gene id: 1125411:W908_RS07950
uniprot id: A0A0M4LQV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1125411:W908 RS02825
gene id: 1125411:W908_RS02825
uniprot id: A0A0M3T1T5
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1125411:W908 RS00280
gene id: 1125411:W908_RS00280
uniprot id: A0A0M4M176
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1125411:W908 RS01815
gene id: 1125411:W908_RS01815
uniprot id: A0A0M3T1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS08655
gene id: 1125411:W908_RS08655
uniprot id: A0A0M5KWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1125411:W908 RS03865
gene id: 1125411:W908_RS03865
uniprot id: A0A0M4M2H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1125411:W908 RS05630
gene id: 1125411:W908_RS05630
uniprot id: A0A0M4LFT4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1125411:W908 RS06320
gene id: 1125411:W908_RS06320
uniprot id: A0A0M4LIC5
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

1125411:W908 RS05765
gene id: 1125411:W908_RS05765
uniprot id: A0A0M4M0I5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1125411:W908 RS00550
gene id: 1125411:W908_RS00550
uniprot id: A0A0M4LE39
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1125411:W908 RS02980
gene id: 1125411:W908_RS02980
uniprot id: A0A0M4L4Z2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1125411:W908 RS07555
gene id: 1125411:W908_RS07555
uniprot id: A0A0M4LGC9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1125411:W908 RS01715
gene id: 1125411:W908_RS01715
uniprot id: A0A0M4LZ77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS04015
gene id: 1125411:W908_RS04015
uniprot id: A0A0M4LFB3
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1125411:W908 RS02395
gene id: 1125411:W908_RS02395
uniprot id: A0A0M5KYC9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1125411:W908 RS08545
gene id: 1125411:W908_RS08545
uniprot id: A0A0M5KS52
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01485
gene id: 1125411:W908_RS01485
uniprot id: A0A0M4LCE7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1125411:W908 RS02260
gene id: 1125411:W908_RS02260
uniprot id: A0A0M4LES0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1125411:W908 RS05335
gene id: 1125411:W908_RS05335
uniprot id: A0A0M4LDL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1125411:W908 RS03905
gene id: 1125411:W908_RS03905
uniprot id: A0A0M5KTR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1125411:W908 RS05445
gene id: 1125411:W908_RS05445
uniprot id: A0A0M4L5P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1125411:W908 RS00025
gene id: 1125411:W908_RS00025
uniprot id: A0A0M5KZZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1125411:W908 RS07910
gene id: 1125411:W908_RS07910
uniprot id: A0A0M4LHV1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1125411:W908 RS05410
gene id: 1125411:W908_RS05410
uniprot id: A0A0M3T230
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1125411:W908 RS02640
gene id: 1125411:W908_RS02640
uniprot id: A0A0M4L3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1125411:W908 RS07940
gene id: 1125411:W908_RS07940
uniprot id: A0A0M4L563
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS01555
gene id: 1125411:W908_RS01555
uniprot id: A0A0M4LCF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1125411:W908 RS02820
gene id: 1125411:W908_RS02820
uniprot id: A0A0M4LF09
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1125411:W908 RS06485
gene id: 1125411:W908_RS06485
uniprot id: A0A0M4LQC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1125411:W908 RS03830
gene id: 1125411:W908_RS03830
uniprot id: A0A0M3T1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1125411:W908 RS01560
gene id: 1125411:W908_RS01560
uniprot id: A0A0M4L3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS07960
gene id: 1125411:W908_RS07960
uniprot id: A0A0M4M199
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1125411:W908 RS03840
gene id: 1125411:W908_RS03840
uniprot id: A0A0M4LZV8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1125411:W908 RS06385
gene id: 1125411:W908_RS06385
uniprot id: A0A0M4LHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1125411:W908 RS01655
gene id: 1125411:W908_RS01655
uniprot id: A0A0M3T1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1125411:W908 RS07400
gene id: 1125411:W908_RS07400
uniprot id: A0A0M3T2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS01120
gene id: 1125411:W908_RS01120
uniprot id: A0A0M4LYZ1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1125411:W908 RS01145
gene id: 1125411:W908_RS01145
uniprot id: A0A0M4M1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS01580
gene id: 1125411:W908_RS01580
uniprot id: A0A0M3T1N4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1125411:W908 RS02495
gene id: 1125411:W908_RS02495
uniprot id: A0A0M4LNY5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1125411:W908 RS02750
gene id: 1125411:W908_RS02750
uniprot id: A0A0M5KYE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1125411:W908 RS05970
gene id: 1125411:W908_RS05970
uniprot id: A0A0M4LDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1125411:W908 RS05540
gene id: 1125411:W908_RS05540
uniprot id: A0A0M4L5Q1
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS06700
gene id: 1125411:W908_RS06700
uniprot id: A0A0M4M0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1125411:W908 RS06230
gene id: 1125411:W908_RS06230
uniprot id: A0A0M3T246
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1125411:W908 RS06440
gene id: 1125411:W908_RS06440
uniprot id: A0A0M4L601
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS01775
gene id: 1125411:W908_RS01775
uniprot id: A0A0M5L046
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1125411:W908 RS00335
gene id: 1125411:W908_RS00335
uniprot id: A0A0M5KRH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1125411:W908 RS01325
gene id: 1125411:W908_RS01325
uniprot id: A0A0M4LZ22
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02685
gene id: 1125411:W908_RS02685
uniprot id: A0A0M4M233
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS06720
gene id: 1125411:W908_RS06720
uniprot id: A0A0M4LHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1125411:W908 RS01610
gene id: 1125411:W908_RS01610
uniprot id: A0A0M4M1Q1
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1125411:W908 RS00075
gene id: 1125411:W908_RS00075
uniprot id: A0A0M3T1K9
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS04020
gene id: 1125411:W908_RS04020
uniprot id: A0A0M4LD72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1125411:W908 RS03555
gene id: 1125411:W908_RS03555
uniprot id: A0A0M4LD14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1125411:W908 RS03280
gene id: 1125411:W908_RS03280
uniprot id: A0A0M4LF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1125411:W908 RS03945
gene id: 1125411:W908_RS03945
uniprot id: A0A0M4M2I4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1125411:W908 RS05910
gene id: 1125411:W908_RS05910
uniprot id: A0A0M3T234
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1125411:W908 RS03915
gene id: 1125411:W908_RS03915
uniprot id: A0A0M4L594
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1125411:W908 RS04975
gene id: 1125411:W908_RS04975
uniprot id: A0A0M4LFL8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1125411:W908 RS01470
gene id: 1125411:W908_RS01470
uniprot id: A0A0M3T1N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1125411:W908 RS06070
gene id: 1125411:W908_RS06070
uniprot id: A0A0M4L5V6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1125411:W908 RS04250
gene id: 1125411:W908_RS04250
uniprot id: A0A0M4L5D2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1125411:W908 RS04065
gene id: 1125411:W908_RS04065
uniprot id: A0A0M4LGL4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1125411:W908 RS07595
gene id: 1125411:W908_RS07595
uniprot id: A0A0M4LF56
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer.

1125411:W908 RS05925
gene id: 1125411:W908_RS05925
uniprot id: A0A0M5L0D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS07920
gene id: 1125411:W908_RS07920
uniprot id: A0A0M5KS24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1125411:W908 RS02655
gene id: 1125411:W908_RS02655
uniprot id: A0A0M5KRM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1125411:W908 RS04770
gene id: 1125411:W908_RS04770
uniprot id: A0A0M5KRU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1125411:W908 RS07140
gene id: 1125411:W908_RS07140
uniprot id: A0A0M5KS78
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS07340
gene id: 1125411:W908_RS07340
uniprot id: A0A0M4LHM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS03795
gene id: 1125411:W908_RS03795
uniprot id: A0A0M5KRQ8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1125411:W908 RS01320
gene id: 1125411:W908_RS01320
uniprot id: A0A0M3T1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1125411:W908 RS05890
gene id: 1125411:W908_RS05890
uniprot id: A0A0M4M347
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1125411:W908 RS00820
gene id: 1125411:W908_RS00820
uniprot id: A0A0M3T1K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1125411:W908 RS01390
gene id: 1125411:W908_RS01390
uniprot id: A0A0M3T1P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1125411:W908 RS08235
gene id: 1125411:W908_RS08235
uniprot id: A0A0M3T2C9
names: Similarity
messages: Belongs to the CIA30 family.

1125411:W908 RS04200
gene id: 1125411:W908_RS04200
uniprot id: A0A0M4M4B5
names: Similarity
messages: Belongs to the Skp family.

1125411:W908 RS02100
gene id: 1125411:W908_RS02100
uniprot id: A0A0M3T1S2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06005
gene id: 1125411:W908_RS06005
uniprot id: A0A0M4LH81
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1125411:W908 RS07090
gene id: 1125411:W908_RS07090
uniprot id: A0A0M3T274
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS03540
gene id: 1125411:W908_RS03540
uniprot id: A0A0M4M2C4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1125411:W908 RS03690
gene id: 1125411:W908_RS03690
uniprot id: A0A0M4L3X5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1125411:W908 RS03035
gene id: 1125411:W908_RS03035
uniprot id: A0A0M5KRN8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1125411:W908 RS00800
gene id: 1125411:W908_RS00800
uniprot id: A0A0M4LFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1125411:W908 RS04690
gene id: 1125411:W908_RS04690
uniprot id: A0A0M3T207
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1125411:W908 RS03725
gene id: 1125411:W908_RS03725
uniprot id: A0A0M3T1X5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1125411:W908 RS02665
gene id: 1125411:W908_RS02665
uniprot id: A0A0M4L4W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS04270
gene id: 1125411:W908_RS04270
uniprot id: A0A0M4M2M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1125411:W908 RS00785
gene id: 1125411:W908_RS00785
uniprot id: A0A0M4LYV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06000
gene id: 1125411:W908_RS06000
uniprot id: A0A0M4L5U8
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1125411:W908 RS08415
gene id: 1125411:W908_RS08415
uniprot id: A0A0M3T2B1
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS03765
gene id: 1125411:W908_RS03765
uniprot id: A0A0M4LPF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1125411:W908 RS01340
gene id: 1125411:W908_RS01340
uniprot id: A0A0M3T1P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1125411:W908 RS00050
gene id: 1125411:W908_RS00050
uniprot id: A0A0M5KRF3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1125411:W908 RS07425
gene id: 1125411:W908_RS07425
uniprot id: A0A0M4LGA9
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS08555
gene id: 1125411:W908_RS08555
uniprot id: A0A0M4LGQ1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1125411:W908 RS07760
gene id: 1125411:W908_RS07760
uniprot id: A0A0M5L0I4
names: Similarity
messages: Belongs to the glutamate synthase family.

1125411:W908 RS03825
gene id: 1125411:W908_RS03825
uniprot id: A0A0M4LPG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01035
gene id: 1125411:W908_RS01035
uniprot id: A0A0M4L4E1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1125411:W908 RS03215
gene id: 1125411:W908_RS03215
uniprot id: A0A0M4LGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1125411:W908 RS02220
gene id: 1125411:W908_RS02220
uniprot id: A0A0M4LEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1125411:W908 RS05405
gene id: 1125411:W908_RS05405
uniprot id: A0A0M4LDM9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1125411:W908 RS02690
gene id: 1125411:W908_RS02690
uniprot id: A0A0M3T1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02625
gene id: 1125411:W908_RS02625
uniprot id: A0A0M4LCS6
names: Similarity
messages: Belongs to the PhoH family.

1125411:W908 RS02115
gene id: 1125411:W908_RS02115
uniprot id: A0A0M4L3I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS05030
gene id: 1125411:W908_RS05030
uniprot id: A0A0M4M2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS02855
gene id: 1125411:W908_RS02855
uniprot id: A0A0M5L081
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1125411:W908 RS05810
gene id: 1125411:W908_RS05810
uniprot id: A0A0M4LFU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1125411:W908 RS07200
gene id: 1125411:W908_RS07200
uniprot id: A0A0M4M103
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1125411:W908 RS08540
gene id: 1125411:W908_RS08540
uniprot id: A0A0M3T2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1125411:W908 RS05425
gene id: 1125411:W908_RS05425
uniprot id: A0A0M4LPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1125411:W908 RS07485
gene id: 1125411:W908_RS07485
uniprot id: A0A0M4M3Q1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1125411:W908 RS02295
gene id: 1125411:W908_RS02295
uniprot id: A0A0M5KRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1125411:W908 RS08535
gene id: 1125411:W908_RS08535
uniprot id: A0A0M4LI14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06155
gene id: 1125411:W908_RS06155
uniprot id: A0A0M5KT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1125411:W908 RS03075
gene id: 1125411:W908_RS03075
uniprot id: A0A0M4LF25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1125411:W908 RS05755
gene id: 1125411:W908_RS05755
uniprot id: A0A0M4LQ30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1125411:W908 RS04600
gene id: 1125411:W908_RS04600
uniprot id: A0A0M5KRS9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1125411:W908 RS03370
gene id: 1125411:W908_RS03370
uniprot id: A0A0M3T1W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1125411:W908 RS00970
gene id: 1125411:W908_RS00970
uniprot id: A0A0M3T1L0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS04245
gene id: 1125411:W908_RS04245
uniprot id: A0A0M4M016
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1125411:W908 RS02890
gene id: 1125411:W908_RS02890
uniprot id: A0A0M4M260
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1125411:W908 RS00110
gene id: 1125411:W908_RS00110
uniprot id: A0A0M5KVV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1125411:W908 RS01475
gene id: 1125411:W908_RS01475
uniprot id: A0A0M4M1P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1125411:W908 RS06350
gene id: 1125411:W908_RS06350
uniprot id: A0A0M5L0H0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1125411:W908 RS06010
gene id: 1125411:W908_RS06010
uniprot id: A0A0M5KRX2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1125411:W908 RS06390
gene id: 1125411:W908_RS06390
uniprot id: A0A0M5KRY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1125411:W908 RS07685
gene id: 1125411:W908_RS07685
uniprot id: A0A0M4M3S5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS00735
gene id: 1125411:W908_RS00735
uniprot id: A0A0M5KRH3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1125411:W908 RS07570
gene id: 1125411:W908_RS07570
uniprot id: A0A0M4LQQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1125411:W908 RS01495
gene id: 1125411:W908_RS01495
uniprot id: A0A0M4L3B6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1125411:W908 RS07305
gene id: 1125411:W908_RS07305
uniprot id: A0A0M4LEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1125411:W908 RS03550
gene id: 1125411:W908_RS03550
uniprot id: A0A0M3T1V4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02240
gene id: 1125411:W908_RS02240
uniprot id: A0A0M4L4R9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1125411:W908 RS00795
gene id: 1125411:W908_RS00795
uniprot id: A0A0M4L4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1125411:W908 RS06575
gene id: 1125411:W908_RS06575
uniprot id: A0A0M4LHE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1125411:W908 RS05575
gene id: 1125411:W908_RS05575
uniprot id: A0A0M4LDP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1125411:W908 RS01650
gene id: 1125411:W908_RS01650
uniprot id: A0A0M4LZ66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1125411:W908 RS03485
gene id: 1125411:W908_RS03485
uniprot id: A0A0M4LD06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1125411:W908 RS01365
gene id: 1125411:W908_RS01365
uniprot id: A0A0M4L3A2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1125411:W908 RS04160
gene id: 1125411:W908_RS04160
uniprot id: A0A0M4L417
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1125411:W908 RS03895
gene id: 1125411:W908_RS03895
uniprot id: A0A0M4L3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1125411:W908 RS08510
gene id: 1125411:W908_RS08510
uniprot id: A0A0M4LR19
names: Similarity
messages: Belongs to the SCO1/2 family.

1125411:W908 RS02465
gene id: 1125411:W908_RS02465
uniprot id: A0A0M4M204
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1125411:W908 RS04145
gene id: 1125411:W908_RS04145
uniprot id: A0A0M4LFD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1125411:W908 RS02145
gene id: 1125411:W908_RS02145
uniprot id: A0A0M4LG22
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1125411:W908 RS06660
gene id: 1125411:W908_RS06660
uniprot id: A0A0M4M3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1125411:W908 RS01770
gene id: 1125411:W908_RS01770
uniprot id: A0A0M4LNQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1125411:W908 RS06535
gene id: 1125411:W908_RS06535
uniprot id: A0A0M4LH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1125411:W908 RS02170
gene id: 1125411:W908_RS02170
uniprot id: A0A0M4M1X0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1125411:W908 RS06425
gene id: 1125411:W908_RS06425
uniprot id: A0A0M5KWD1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1125411:W908 RS07775
gene id: 1125411:W908_RS07775
uniprot id: A0A0M4LHT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1125411:W908 RS04205
gene id: 1125411:W908_RS04205
uniprot id: A0A0M4M2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1125411:W908 RS01250
gene id: 1125411:W908_RS01250
uniprot id: A0A0M4L4H1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1125411:W908 RS02865
gene id: 1125411:W908_RS02865
uniprot id: A0A0M4LZL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1125411:W908 RS03715
gene id: 1125411:W908_RS03715
uniprot id: A0A0M4L571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1125411:W908 RS02440
gene id: 1125411:W908_RS02440
uniprot id: A0A0M4LZF9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1125411:W908 RS06975
gene id: 1125411:W908_RS06975
uniprot id: A0A0M3T281
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1125411:W908 RS01220
gene id: 1125411:W908_RS01220
uniprot id: A0A0M4LCB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1125411:W908 RS00805
gene id: 1125411:W908_RS00805
uniprot id: A0A0M5KRH2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1125411:W908 RS01205
gene id: 1125411:W908_RS01205
uniprot id: A0A0M3T1L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1125411:W908 RS06065
gene id: 1125411:W908_RS06065
uniprot id: A0A0M4M0L8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1125411:W908 RS04155
gene id: 1125411:W908_RS04155
uniprot id: A0A0M3T1Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1125411:W908 RS03300
gene id: 1125411:W908_RS03300
uniprot id: A0A0M4L3U0
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00390
gene id: 1125411:W908_RS00390
uniprot id: A0A0M4L472
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1125411:W908 RS07655
gene id: 1125411:W908_RS07655
uniprot id: A0A0M5KU24
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1125411:W908 RS03810
gene id: 1125411:W908_RS03810
uniprot id: A0A0M3T1W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1125411:W908 RS03870
gene id: 1125411:W908_RS03870
uniprot id: A0A0M4LF95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1125411:W908 RS07780
gene id: 1125411:W908_RS07780
uniprot id: A0A0M5KS30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1125411:W908 RS02565
gene id: 1125411:W908_RS02565
uniprot id: A0A0M4L3M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1125411:W908 RS03530
gene id: 1125411:W908_RS03530
uniprot id: A0A0M5KU60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1125411:W908 RS00275
gene id: 1125411:W908_RS00275
uniprot id: A0A0M5KY70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1125411:W908 RS02905
gene id: 1125411:W908_RS02905
uniprot id: A0A0M4LCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1125411:W908 RS04710
gene id: 1125411:W908_RS04710
uniprot id: A0A0M4M2R8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1125411:W908 RS01450
gene id: 1125411:W908_RS01450
uniprot id: A0A0M4LZ38
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1125411:W908 RS04840
gene id: 1125411:W908_RS04840
uniprot id: A0A0M5L0D0
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1125411:W908 RS07890
gene id: 1125411:W908_RS07890
uniprot id: A0A0M5KWH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1125411:W908 RS05210
gene id: 1125411:W908_RS05210
uniprot id: A0A0M5L0E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1125411:W908 RS00135
gene id: 1125411:W908_RS00135
uniprot id: A0A0M5KRF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1125411:W908 RS02060
gene id: 1125411:W908_RS02060
uniprot id: A0A0M5L031
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1125411:W908 RS01415
gene id: 1125411:W908_RS01415
uniprot id: A0A0M4LEI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1125411:W908 RS03275
gene id: 1125411:W908_RS03275
uniprot id: A0A0M4M298
names: Similarity
messages: Belongs to the GSP E family.

1125411:W908 RS03510
gene id: 1125411:W908_RS03510
uniprot id: A0A0M4LZR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1125411:W908 RS06680
gene id: 1125411:W908_RS06680
uniprot id: A0A0M4LQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1125411:W908 RS05590
gene id: 1125411:W908_RS05590
uniprot id: A0A0M4LQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01430
gene id: 1125411:W908_RS01430
uniprot id: A0A0M4L3A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1125411:W908 RS01285
gene id: 1125411:W908_RS01285
uniprot id: A0A0M4LCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1125411:W908 RS07320
gene id: 1125411:W908_RS07320
uniprot id: A0A0M5KU12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1125411:W908 RS03455
gene id: 1125411:W908_RS03455
uniprot id: A0A0M3T1W5
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1125411:W908 RS02795
gene id: 1125411:W908_RS02795
uniprot id: A0A0M3T1U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1125411:W908 RS08605
gene id: 1125411:W908_RS08605
uniprot id: A0A0M4LI22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1125411:W908 RS00570
gene id: 1125411:W908_RS00570
uniprot id: A0A0M4LN91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: Homotetramer.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1125411:W908 RS02385
gene id: 1125411:W908_RS02385
uniprot id: A0A0M3T1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1125411:W908 RS04695
gene id: 1125411:W908_RS04695
uniprot id: A0A0M4L5G6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1125411:W908 RS01800
gene id: 1125411:W908_RS01800
uniprot id: A0A0M4LFV3
names: Similarity
messages: Belongs to the peptidase U62 family.

1125411:W908 RS07905
gene id: 1125411:W908_RS07905
uniprot id: A0A0M4L6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1125411:W908 RS03705
gene id: 1125411:W908_RS03705
uniprot id: A0A0M3T1W0
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS02530
gene id: 1125411:W908_RS02530
uniprot id: A0A0M5KRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1125411:W908 RS07650
gene id: 1125411:W908_RS07650
uniprot id: A0A0M4LQR9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02770
gene id: 1125411:W908_RS02770
uniprot id: A0A0M4L3P6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1125411:W908 RS03990
gene id: 1125411:W908_RS03990
uniprot id: A0A0M4L5A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1125411:W908 RS03575
gene id: 1125411:W908_RS03575
uniprot id: A0A0M3T1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1125411:W908 RS06225
gene id: 1125411:W908_RS06225
uniprot id: A0A0M4LFZ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1125411:W908 RS08385
gene id: 1125411:W908_RS08385
uniprot id: A0A0M4L6K1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1125411:W908 RS06505
gene id: 1125411:W908_RS06505
uniprot id: A0A0M4L609
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1125411:W908 RS07240
gene id: 1125411:W908_RS07240
uniprot id: A0A0M4LE93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1125411:W908 RS04220
gene id: 1125411:W908_RS04220
uniprot id: A0A0M4LD95
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1125411:W908 RS01420
gene id: 1125411:W908_RS01420
uniprot id: A0A0M3T1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1125411:W908 RS07545
gene id: 1125411:W908_RS07545
uniprot id: A0A0M4M3Q9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1125411:W908 RS08025
gene id: 1125411:W908_RS08025
uniprot id: A0A0M4M1A8
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00045
gene id: 1125411:W908_RS00045
uniprot id: A0A0M4LF58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1125411:W908 RS04605
gene id: 1125411:W908_RS04605
uniprot id: A0A0M3T1Z0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1125411:W908 RS02610
gene id: 1125411:W908_RS02610
uniprot id: A0A0M3T1S8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1125411:W908 RS07845
gene id: 1125411:W908_RS07845
uniprot id: A0A0M3T297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1125411:W908 RS02700
gene id: 1125411:W908_RS02700
uniprot id: A0A0M4LCS8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1125411:W908 RS06020
gene id: 1125411:W908_RS06020
uniprot id: A0A0M4M363
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1125411:W908 RS08320
gene id: 1125411:W908_RS08320
uniprot id: A0A0M4L6J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1125411:W908 RS07970
gene id: 1125411:W908_RS07970
uniprot id: A0A0M4L6G4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1125411:W908 RS02670
gene id: 1125411:W908_RS02670
uniprot id: A0A0M3T1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1125411:W908 RS03755
gene id: 1125411:W908_RS03755
uniprot id: A0A0M4L3Y3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1125411:W908 RS08425
gene id: 1125411:W908_RS08425
uniprot id: A0A0M4LGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS05830
gene id: 1125411:W908_RS05830
uniprot id: A0A0M4LQ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1125411:W908 RS03055
gene id: 1125411:W908_RS03055
uniprot id: A0A0M4LGB5
names: Similarity
messages: Belongs to the histone deacetylase family.

1125411:W908 RS02705
gene id: 1125411:W908_RS02705
uniprot id: A0A0M4L3N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1125411:W908 RS05440
gene id: 1125411:W908_RS05440
uniprot id: A0A0M4M0E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1125411:W908 RS02085
gene id: 1125411:W908_RS02085
uniprot id: A0A0M4LFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1125411:W908 RS05130
gene id: 1125411:W908_RS05130
uniprot id: A0A0M4LDJ1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1125411:W908 RS00095
gene id: 1125411:W908_RS00095
uniprot id: A0A0M5KS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1125411:W908 RS06075
gene id: 1125411:W908_RS06075
uniprot id: A0A0M3T240
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1125411:W908 RS05365
gene id: 1125411:W908_RS05365
uniprot id: A0A0M4L5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS08505
gene id: 1125411:W908_RS08505
uniprot id: A0A0M4L5C3
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS05000
gene id: 1125411:W908_RS05000
uniprot id: A0A0M5KRU2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1125411:W908 RS03395
gene id: 1125411:W908_RS03395
uniprot id: A0A0M5KW50
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1125411:W908 RS01825
gene id: 1125411:W908_RS01825
uniprot id: A0A0M4LEM5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1125411:W908 RS06275
gene id: 1125411:W908_RS06275
uniprot id: A0A0M4M0P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1125411:W908 RS01030
gene id: 1125411:W908_RS01030
uniprot id: A0A0M4LYY0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1125411:W908 RS02810
gene id: 1125411:W908_RS02810
uniprot id: A0A0M5KRP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1125411:W908 RS03850
gene id: 1125411:W908_RS03850
uniprot id: A0A0M4LGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1125411:W908 RS07670
gene id: 1125411:W908_RS07670
uniprot id: A0A0M4L6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1125411:W908 RS02830
gene id: 1125411:W908_RS02830
uniprot id: A0A0M4LCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1125411:W908 RS06240
gene id: 1125411:W908_RS06240
uniprot id: A0A0M4L4L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS08360
gene id: 1125411:W908_RS08360
uniprot id: A0A0M4L5A9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1125411:W908 RS03900
gene id: 1125411:W908_RS03900
uniprot id: A0A0M4LPG9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1125411:W908 RS02330
gene id: 1125411:W908_RS02330
uniprot id: A0A0M4L6Q4
names: Similarity
messages: Belongs to the intimin/invasin family.

1125411:W908 RS04115
gene id: 1125411:W908_RS04115
uniprot id: A0A0M4LZZ9
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1125411:W908 RS03835
gene id: 1125411:W908_RS03835
uniprot id: A0A0M5KRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1125411:W908 RS01855
gene id: 1125411:W908_RS01855
uniprot id: A0A0M4LZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS04585
gene id: 1125411:W908_RS04585
uniprot id: A0A0M4LPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1125411:W908 RS00905
gene id: 1125411:W908_RS00905
uniprot id: A0A0M5KTB5
names: Similarity
messages: Belongs to the arginase family.

1125411:W908 RS04700
gene id: 1125411:W908_RS04700
uniprot id: A0A0M4LGS5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1125411:W908 RS08345
gene id: 1125411:W908_RS08345
uniprot id: A0A0M3T2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1125411:W908 RS04420
gene id: 1125411:W908_RS04420
uniprot id: A0A0M4LFG9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1125411:W908 RS04310
gene id: 1125411:W908_RS04310
uniprot id: A0A0M5L093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS07740
gene id: 1125411:W908_RS07740
uniprot id: A0A0M4LEF0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1125411:W908 RS05815
gene id: 1125411:W908_RS05815
uniprot id: A0A0M4LDS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1125411:W908 RS01945
gene id: 1125411:W908_RS01945
uniprot id: A0A0M5KSU3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1125411:W908 RS06870
gene id: 1125411:W908_RS06870
uniprot id: A0A0M4M3H2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1125411:W908 RS07825
gene id: 1125411:W908_RS07825
uniprot id: A0A0M4LQT8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1125411:W908 RS03800
gene id: 1125411:W908_RS03800
uniprot id: A0A0M4M2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1125411:W908 RS02760
gene id: 1125411:W908_RS02760
uniprot id: A0A0M4LF02
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1125411:W908 RS01840
gene id: 1125411:W908_RS01840
uniprot id: A0A0M4LNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1125411:W908 RS06420
gene id: 1125411:W908_RS06420
uniprot id: A0A0M4LQB4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1125411:W908 RS04255
gene id: 1125411:W908_RS04255
uniprot id: A0A0M4LGN5
names: Similarity
messages: Belongs to the UPF0250 family.

1125411:W908 RS05655
gene id: 1125411:W908_RS05655
uniprot id: A0A0M4LQ21
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS05300
gene id: 1125411:W908_RS05300
uniprot id: A0A0M3T226
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS01810
gene id: 1125411:W908_RS01810
uniprot id: A0A0M4M1S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1125411:W908 RS05310
gene id: 1125411:W908_RS05310
uniprot id: A0A0M4LGY7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1125411:W908 RS07980
gene id: 1125411:W908_RS07980
uniprot id: A0A0M5KT98
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1125411:W908 RS01925
gene id: 1125411:W908_RS01925
uniprot id: A0A0M4LZ99
names: Similarity
messages: Belongs to the glutamine synthetase family.

1125411:W908 RS07430
gene id: 1125411:W908_RS07430
uniprot id: A0A0M3T287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1125411:W908 RS03385
gene id: 1125411:W908_RS03385
uniprot id: A0A0M4L3U6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1125411:W908 RS05865
gene id: 1125411:W908_RS05865
uniprot id: A0A0M4M0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1125411:W908 RS02030
gene id: 1125411:W908_RS02030
uniprot id: A0A0M4LEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1125411:W908 RS04900
gene id: 1125411:W908_RS04900
uniprot id: A0A0M3T212
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1125411:W908 RS06780
gene id: 1125411:W908_RS06780
uniprot id: A0A0M4L641
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS07630
gene id: 1125411:W908_RS07630
uniprot id: A0A0M4LGD8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS00300
gene id: 1125411:W908_RS00300
uniprot id: A0A0M4L2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1125411:W908 RS03920
gene id: 1125411:W908_RS03920
uniprot id: A0A0M3T1W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS02010
gene id: 1125411:W908_RS02010
uniprot id: A0A0M5KYB8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS06655
gene id: 1125411:W908_RS06655
uniprot id: A0A0M5KRZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1125411:W908 RS01755
gene id: 1125411:W908_RS01755
uniprot id: A0A0M4LCI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1125411:W908 RS00315
gene id: 1125411:W908_RS00315
uniprot id: A0A0M5KZY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1125411:W908 RS05735
gene id: 1125411:W908_RS05735
uniprot id: A0A0M4LDR2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1125411:W908 RS00645
gene id: 1125411:W908_RS00645
uniprot id: A0A0M4LYT4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1125411:W908 RS07965
gene id: 1125411:W908_RS07965
uniprot id: A0A0M3T2C1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1125411:W908 RS02800
gene id: 1125411:W908_RS02800
uniprot id: A0A0M4L4X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1125411:W908 RS07260
gene id: 1125411:W908_RS07260
uniprot id: A0A0M5KS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1125411:W908 RS07115
gene id: 1125411:W908_RS07115
uniprot id: A0A0M3T284
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1125411:W908 RS05155
gene id: 1125411:W908_RS05155
uniprot id: A0A0M4M0B4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1125411:W908 RS01165
gene id: 1125411:W908_RS01165
uniprot id: A0A0M4L367
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1125411:W908 RS01405
gene id: 1125411:W908_RS01405
uniprot id: A0A0M5KRK8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1125411:W908 RS01570
gene id: 1125411:W908_RS01570
uniprot id: A0A0M5KRJ6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1125411:W908 RS01090
gene id: 1125411:W908_RS01090
uniprot id: A0A0M4L356
names: Similarity
messages: Belongs to the UxaA family.

1125411:W908 RS08365
gene id: 1125411:W908_RS08365
uniprot id: A0A0M4LQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1125411:W908 RS02915
gene id: 1125411:W908_RS02915
uniprot id: A0A0M4L3R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS03580
gene id: 1125411:W908_RS03580
uniprot id: A0A0M5KTQ4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS01865
gene id: 1125411:W908_RS01865
uniprot id: A0A0M4LFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1125411:W908 RS07800
gene id: 1125411:W908_RS07800
uniprot id: A0A0M4M3T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1125411:W908 RS01665
gene id: 1125411:W908_RS01665
uniprot id: A0A0M4LFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1125411:W908 RS03930
gene id: 1125411:W908_RS03930
uniprot id: A0A0M4LGJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1125411:W908 RS07245
gene id: 1125411:W908_RS07245
uniprot id: A0A0M3T288
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1125411:W908 RS06670
gene id: 1125411:W908_RS06670
uniprot id: A0A0M4LE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1125411:W908 RS02535
gene id: 1125411:W908_RS02535
uniprot id: A0A0M4M215
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1125411:W908 RS08520
gene id: 1125411:W908_RS08520
uniprot id: A0A0M3T2B5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1125411:W908 RS05965
gene id: 1125411:W908_RS05965
uniprot id: A0A0M3T236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1125411:W908 RS07755
gene id: 1125411:W908_RS07755
uniprot id: A0A0M3T2B4
names: Similarity
messages: Belongs to the UPF0246 family.

1125411:W908 RS08625
gene id: 1125411:W908_RS08625
uniprot id: A0A0M3T2B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS00950
gene id: 1125411:W908_RS00950
uniprot id: A0A0M4LND3
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS08495
gene id: 1125411:W908_RS08495
uniprot id: A0A0M4LGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1125411:W908 RS08485
gene id: 1125411:W908_RS08485
uniprot id: A0A0M4M420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1125411:W908 RS07420
gene id: 1125411:W908_RS07420
uniprot id: A0A0M4M3P2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1125411:W908 RS05330
gene id: 1125411:W908_RS05330
uniprot id: A0A0M3T215
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1125411:W908 RS03505
gene id: 1125411:W908_RS03505
uniprot id: A0A0M5KRP6
names: Subcellular Location Annotation
messages: Mitochondrion

1125411:W908 RS03015
gene id: 1125411:W908_RS03015
uniprot id: A0A0M4LF20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1125411:W908 RS00145
gene id: 1125411:W908_RS00145
uniprot id: A0A0M3T1L1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1125411:W908 RS06160
gene id: 1125411:W908_RS06160
uniprot id: A0A0M4M379
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1125411:W908 RS05290
gene id: 1125411:W908_RS05290
uniprot id: A0A0M5KWA0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1125411:W908 RS05070
gene id: 1125411:W908_RS05070
uniprot id: A0A0M4LPV1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1125411:W908 RS01210
gene id: 1125411:W908_RS01210
uniprot id: A0A0M4M1K6
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00940
gene id: 1125411:W908_RS00940
uniprot id: A0A0M3T1N7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1125411:W908 RS01765
gene id: 1125411:W908_RS01765
uniprot id: A0A0M4L3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1125411:W908 RS06215
gene id: 1125411:W908_RS06215
uniprot id: A0A0M5KYN3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1125411:W908 RS00445
gene id: 1125411:W908_RS00445
uniprot id: A0A0M3T1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS07565
gene id: 1125411:W908_RS07565
uniprot id: A0A0M4L514
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1125411:W908 RS02730
gene id: 1125411:W908_RS02730
uniprot id: A0A0M4LZJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1125411:W908 RS02425
gene id: 1125411:W908_RS02425
uniprot id: A0A0M4LNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02405
gene id: 1125411:W908_RS02405
uniprot id: A0A0M3T1T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1125411:W908 RS04620
gene id: 1125411:W908_RS04620
uniprot id: A0A0M4L5F8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1125411:W908 RS06740
gene id: 1125411:W908_RS06740
uniprot id: A0A0M4LG44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1125411:W908 RS02005
gene id: 1125411:W908_RS02005
uniprot id: A0A0M4LFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1125411:W908 RS07850
gene id: 1125411:W908_RS07850
uniprot id: A0A0M4LHU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1125411:W908 RS07510
gene id: 1125411:W908_RS07510
uniprot id: A0A0M4LQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1125411:W908 RS07225
gene id: 1125411:W908_RS07225
uniprot id: A0A0M4LH58
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS06600
gene id: 1125411:W908_RS06600
uniprot id: A0A0M4LG26
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1125411:W908 RS00005
gene id: 1125411:W908_RS00005
uniprot id: A0A0M4L2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1125411:W908 RS05585
gene id: 1125411:W908_RS05585
uniprot id: A0A0M3T223
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS04925
gene id: 1125411:W908_RS04925
uniprot id: A0A0M5KW88
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1125411:W908 RS07820
gene id: 1125411:W908_RS07820
uniprot id: A0A0M4L548
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1125411:W908 RS07330
gene id: 1125411:W908_RS07330
uniprot id: A0A0M4M121
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1125411:W908 RS08100
gene id: 1125411:W908_RS08100
uniprot id: A0A0M4LHX4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01860
gene id: 1125411:W908_RS01860
uniprot id: A0A0M4L4N2
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS00200
gene id: 1125411:W908_RS00200
uniprot id: A0A0M3T1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

1125411:W908 RS01375
gene id: 1125411:W908_RS01375
uniprot id: A0A0M4LNJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1125411:W908 RS02755
gene id: 1125411:W908_RS02755
uniprot id: A0A0M4M243
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS04230
gene id: 1125411:W908_RS04230
uniprot id: A0A0M4LPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1125411:W908 RS06580
gene id: 1125411:W908_RS06580
uniprot id: A0A0M5KYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1125411:W908 RS07055
gene id: 1125411:W908_RS07055
uniprot id: A0A0M4LRF8
names: Subcellular Location Annotation
messages: Membrane

1125411:W908 RS07465
gene id: 1125411:W908_RS07465
uniprot id: A0A0M4L6A6
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS01440
gene id: 1125411:W908_RS01440
uniprot id: A0A0M3T1P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1125411:W908 RS06080
gene id: 1125411:W908_RS06080
uniprot id: A0A0M4LH90
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1125411:W908 RS08325
gene id: 1125411:W908_RS08325
uniprot id: A0A0M4LHZ0
names: Similarity
messages: Belongs to the GARS family.

1125411:W908 RS05255
gene id: 1125411:W908_RS05255
uniprot id: A0A0M4M2Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1125411:W908 RS08635
gene id: 1125411:W908_RS08635
uniprot id: A0A0M4L5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1125411:W908 RS01720
gene id: 1125411:W908_RS01720
uniprot id: A0A0M4L4L7
names: Similarity
messages: Belongs to the LOG family.

1125411:W908 RS04750
gene id: 1125411:W908_RS04750
uniprot id: A0A0M4M068
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1125411:W908 RS07995
gene id: 1125411:W908_RS07995
uniprot id: A0A0M3T2A0
names: Similarity
messages: Belongs to the Gfa family.

1125411:W908 RS00245
gene id: 1125411:W908_RS00245
uniprot id: A0A0M4LN44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1125411:W908 RS00065
gene id: 1125411:W908_RS00065
uniprot id: A0A0M4LDX4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1125411:W908 RS08085
gene id: 1125411:W908_RS08085
uniprot id: A0A0M4M1B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1125411:W908 RS06690
gene id: 1125411:W908_RS06690
uniprot id: A0A0M3T262
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1125411:W908 RS05905
gene id: 1125411:W908_RS05905
uniprot id: A0A0M4L4I1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1125411:W908 RS02615
gene id: 1125411:W908_RS02615
uniprot id: A0A0M4M226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1125411:W908 RS04275
gene id: 1125411:W908_RS04275
uniprot id: A0A0M4LFF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1125411:W908 RS06775
gene id: 1125411:W908_RS06775
uniprot id: A0A0M3T275
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1125411:W908 RS06235
gene id: 1125411:W908_RS06235
uniprot id: A0A0M4LDX3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1125411:W908 RS06875
gene id: 1125411:W908_RS06875
uniprot id: A0A0M4LG60
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1125411:W908 RS07395
gene id: 1125411:W908_RS07395
uniprot id: A0A0M3T2G0
names: Similarity
messages: Belongs to the CIA30 family.

1125411:W908 RS01225
gene id: 1125411:W908_RS01225
uniprot id: A0A0M3T1P2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-33 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-33 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-33 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1125411:W908 RS02930
gene id: 1125411:W908_RS02930
uniprot id: A0A0M4LZM0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1125411:W908 RS02265
gene id: 1125411:W908_RS02265
uniprot id: A0A0M3T1R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1125411:W908 RS07385
gene id: 1125411:W908_RS07385
uniprot id: A0A0M5L0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1125411:W908 RS05010
gene id: 1125411:W908_RS05010
uniprot id: A0A0M3T216
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1125411:W908 RS07355
gene id: 1125411:W908_RS07355
uniprot id: A0A0M4M3N0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1125411:W908 RS07590
gene id: 1125411:W908_RS07590
uniprot id: A0A0M4M156
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1125411:W908 RS05270
gene id: 1125411:W908_RS05270
uniprot id: A0A0M4L4C6
names: Subunit
messages: Homodimer.

1125411:W908 RS02025
gene id: 1125411:W908_RS02025
uniprot id: A0A0M4M1V5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1125411:W908 RS05485
gene id: 1125411:W908_RS05485
uniprot id: A0A0M4LFS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1125411:W908 RS05145
gene id: 1125411:W908_RS05145
uniprot id: A0A0M4LPV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1125411:W908 RS00190
gene id: 1125411:W908_RS00190
uniprot id: A0A0M4L450
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1125411:W908 RS05995
gene id: 1125411:W908_RS05995
uniprot id: A0A0M4M0K9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS01685
gene id: 1125411:W908_RS01685
uniprot id: A0A0M3T1P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1125411:W908 RS04950
gene id: 1125411:W908_RS04950
uniprot id: A0A0M4L5I9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1125411:W908 RS00470
gene id: 1125411:W908_RS00470
uniprot id: A0A0M5KRG2
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS02585
gene id: 1125411:W908_RS02585
uniprot id: A0A0M4LZH7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1125411:W908 RS04630
gene id: 1125411:W908_RS04630
uniprot id: A0A0M3T205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1125411:W908 RS00505
gene id: 1125411:W908_RS00505
uniprot id: A0A0M3T1J5
names: Similarity
messages: Belongs to the DapA family.

1125411:W908 RS01670
gene id: 1125411:W908_RS01670
uniprot id: A0A0M5KYA8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1125411:W908 RS07915
gene id: 1125411:W908_RS07915
uniprot id: A0A0M3T2C0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1125411:W908 RS06785
gene id: 1125411:W908_RS06785
uniprot id: A0A0M4LHH0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1125411:W908 RS00295
gene id: 1125411:W908_RS00295
uniprot id: A0A0M4LBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1125411:W908 RS07985
gene id: 1125411:W908_RS07985
uniprot id: A0A0M4M3W0
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1125411:W908 RS04045
gene id: 1125411:W908_RS04045
uniprot id: A0A0M4LZZ1
names: Similarity
messages: Belongs to the GcvT family.

1125411:W908 RS07150
gene id: 1125411:W908_RS07150
uniprot id: A0A0M4LG86
names: Similarity
messages: Belongs to the fabD family.

1125411:W908 RS05680
gene id: 1125411:W908_RS05680
uniprot id: A0A0M4L5R6
names: Similarity
messages: Belongs to the pirin family.

1125411:W908 RS05935
gene id: 1125411:W908_RS05935
uniprot id: A0A0M3T245
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1125411:W908 RS03660
gene id: 1125411:W908_RS03660
uniprot id: A0A0M4LGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1125411:W908 RS01410
gene id: 1125411:W908_RS01410
uniprot id: A0A0M4M1N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1125411:W908 RS03220
gene id: 1125411:W908_RS03220
uniprot id: A0A0M5KRQ5
names: Similarity
messages: Belongs to the GSP E family.

1125411:W908 RS02230
gene id: 1125411:W908_RS02230
uniprot id: A0A0M4LZD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1125411:W908 RS05740
gene id: 1125411:W908_RS05740
uniprot id: A0A0M3T239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1125411:W908 RS08335
gene id: 1125411:W908_RS08335
uniprot id: A0A0M4M3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1125411:W908 RS05380
gene id: 1125411:W908_RS05380
uniprot id: A0A0M5KT31
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1125411:W908 RS04580
gene id: 1125411:W908_RS04580
uniprot id: A0A0M4L454
names: Similarity
messages: Belongs to the peptidase S41A family.

1125411:W908 RS03965
gene id: 1125411:W908_RS03965
uniprot id: A0A0M4L3Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1125411:W908 RS04380
gene id: 1125411:W908_RS04380
uniprot id: A0A0M5L0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1125411:W908 RS07455
gene id: 1125411:W908_RS07455
uniprot id: A0A0M5L0K6
names: Similarity
messages: Belongs to the DDAH family.

1125411:W908 RS00565
gene id: 1125411:W908_RS00565
uniprot id: A0A0M4L301
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1125411:W908 RS00760
gene id: 1125411:W908_RS00760
uniprot id: A0A0M4L327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1125411:W908 RS07875
gene id: 1125411:W908_RS07875
uniprot id: A0A0M4LEG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1125411:W908 RS06795
gene id: 1125411:W908_RS06795
uniprot id: A0A0M4M3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1125411:W908 RS04955
gene id: 1125411:W908_RS04955
uniprot id: A0A0M4LGV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1125411:W908 RS02290
gene id: 1125411:W908_RS02290
uniprot id: A0A0M3T1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1125411:W908 RS02160
gene id: 1125411:W908_RS02160
uniprot id: A0A0M3T1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1125411:W908 RS00670
gene id: 1125411:W908_RS00670
uniprot id: A0A0M4M1D2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1125411:W908 RS06965
gene id: 1125411:W908_RS06965
uniprot id: A0A0M5KYQ3
names: Similarity
messages: Belongs to the TPP enzyme family.

1125411:W908 RS00130
gene id: 1125411:W908_RS00130
uniprot id: A0A0M4LF66
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1125411:W908 RS00690
gene id: 1125411:W908_RS00690
uniprot id: A0A0M4LC41
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1125411:W908 RS04685
gene id: 1125411:W908_RS04685
uniprot id: A0A0M4M063
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.