1123384:THY01S RS05470
gene id: 1123384:THY01S_RS05470
uniprot id: A0A0X1KQ69
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS08950
gene id: 1123384:THY01S_RS08950
uniprot id: A0A0X1KNN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1123384:THY01S RS07635
gene id: 1123384:THY01S_RS07635
uniprot id: A0A0X1KP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS04320
gene id: 1123384:THY01S_RS04320
uniprot id: A0A0X1KSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS10735
gene id: 1123384:THY01S_RS10735
uniprot id: A0A0X1KRL7
names: Similarity
messages: Belongs to the peptidase S8 family.

1123384:THY01S RS08220
gene id: 1123384:THY01S_RS08220
uniprot id: A0A0X1KP38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1123384:THY01S RS07370
gene id: 1123384:THY01S_RS07370
uniprot id: A0A0X1KPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1123384:THY01S RS08035
gene id: 1123384:THY01S_RS08035
uniprot id: A0A0X1KP44
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1123384:THY01S RS07015
gene id: 1123384:THY01S_RS07015
uniprot id: A0A0X1KPJ1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1123384:THY01S RS04945
gene id: 1123384:THY01S_RS04945
uniprot id: A0A0X1KSA9
names: Similarity
messages: Belongs to the creatininase superfamily.

1123384:THY01S RS08810
gene id: 1123384:THY01S_RS08810
uniprot id: A0A0X1KNU0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1123384:THY01S RS06040
gene id: 1123384:THY01S_RS06040
uniprot id: A0A0X1KTV7
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS09010
gene id: 1123384:THY01S_RS09010
uniprot id: A0A0X1KNR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1123384:THY01S RS08815
gene id: 1123384:THY01S_RS08815
uniprot id: A0A0X1KNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1123384:THY01S RS06035
gene id: 1123384:THY01S_RS06035
uniprot id: A0A0X1KPW3
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06815
gene id: 1123384:THY01S_RS06815
uniprot id: A0A0X1KPJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1123384:THY01S RS05410
gene id: 1123384:THY01S_RS05410
uniprot id: A0A0X1KQ28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1123384:THY01S RS08770
gene id: 1123384:THY01S_RS08770
uniprot id: A0A0X1KNM0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1123384:THY01S RS08225
gene id: 1123384:THY01S_RS08225
uniprot id: A0A0X1KNV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1123384:THY01S RS04870
gene id: 1123384:THY01S_RS04870
uniprot id: A0A0X1KS81
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1123384:THY01S RS04780
gene id: 1123384:THY01S_RS04780
uniprot id: A0A0X1KSN1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1123384:THY01S RS00495
gene id: 1123384:THY01S_RS00495
uniprot id: A0A0X1KTS3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS06060
gene id: 1123384:THY01S_RS06060
uniprot id: A0A0X1KPR0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1123384:THY01S RS05535
gene id: 1123384:THY01S_RS05535
uniprot id: A0A0X1KQA8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1123384:THY01S RS00835
gene id: 1123384:THY01S_RS00835
uniprot id: A0A0X1KQS1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1123384:THY01S RS02205
gene id: 1123384:THY01S_RS02205
uniprot id: A0A0X1KRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS03915
gene id: 1123384:THY01S_RS03915
uniprot id: A0A0X1KSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1123384:THY01S RS02640
gene id: 1123384:THY01S_RS02640
uniprot id: A0A0X1KRR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123384:THY01S RS03900
gene id: 1123384:THY01S_RS03900
uniprot id: A0A0X1KSN5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1123384:THY01S RS03590
gene id: 1123384:THY01S_RS03590
uniprot id: A0A0X1KS08
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1123384:THY01S RS01185
gene id: 1123384:THY01S_RS01185
uniprot id: A0A0X1KR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS05205
gene id: 1123384:THY01S_RS05205
uniprot id: A0A0X1KQE0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1123384:THY01S RS02565
gene id: 1123384:THY01S_RS02565
uniprot id: A0A0X1KRW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1123384:THY01S RS05395
gene id: 1123384:THY01S_RS05395
uniprot id: A0A0X1KQ19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1123384:THY01S RS10925
gene id: 1123384:THY01S_RS10925
uniprot id: A0A0X1KRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00705
gene id: 1123384:THY01S_RS00705
uniprot id: A0A0X1KU55
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1123384:THY01S RS01270
gene id: 1123384:THY01S_RS01270
uniprot id: A0A0X1KRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1123384:THY01S RS08400
gene id: 1123384:THY01S_RS08400
uniprot id: A0A0X1KNT4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1123384:THY01S RS00355
gene id: 1123384:THY01S_RS00355
uniprot id: A0A0X1KQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS00330
gene id: 1123384:THY01S_RS00330
uniprot id: A0A0X1KQP1
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1123384:THY01S RS07090
gene id: 1123384:THY01S_RS07090
uniprot id: A0A0X1KPA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1123384:THY01S RS08705
gene id: 1123384:THY01S_RS08705
uniprot id: A0A0X1KNQ0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1123384:THY01S RS05840
gene id: 1123384:THY01S_RS05840
uniprot id: A0A0X1KQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1123384:THY01S RS06565
gene id: 1123384:THY01S_RS06565
uniprot id: A0A0X1KPI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123384:THY01S RS07660
gene id: 1123384:THY01S_RS07660
uniprot id: A0A0X1KP56
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1123384:THY01S RS08195
gene id: 1123384:THY01S_RS08195
uniprot id: A0A0X1KP54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1123384:THY01S RS01385
gene id: 1123384:THY01S_RS01385
uniprot id: A0A0X1KRC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1123384:THY01S RS01770
gene id: 1123384:THY01S_RS01770
uniprot id: A0A0X1KRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1123384:THY01S RS09510
gene id: 1123384:THY01S_RS09510
uniprot id: A0A0X1KTL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1123384:THY01S RS06155
gene id: 1123384:THY01S_RS06155
uniprot id: A0A0X1KPU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123384:THY01S RS08215
gene id: 1123384:THY01S_RS08215
uniprot id: A0A0X1KP39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS06870
gene id: 1123384:THY01S_RS06870
uniprot id: A0A0X1KPI5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1123384:THY01S RS05950
gene id: 1123384:THY01S_RS05950
uniprot id: A0A0X1KPS8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1123384:THY01S RS06160
gene id: 1123384:THY01S_RS06160
uniprot id: A0A0X1KPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1123384:THY01S RS08670
gene id: 1123384:THY01S_RS08670
uniprot id: A0A0X1KNS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123384:THY01S RS08260
gene id: 1123384:THY01S_RS08260
uniprot id: A0A0X1KP04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1123384:THY01S RS00925
gene id: 1123384:THY01S_RS00925
uniprot id: A0A0X1KR62
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06110
gene id: 1123384:THY01S_RS06110
uniprot id: A0A0X1KQ02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS03770
gene id: 1123384:THY01S_RS03770
uniprot id: A0A0X1KS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1123384:THY01S RS06845
gene id: 1123384:THY01S_RS06845
uniprot id: A0A0X1KPD3
names: Similarity
messages: Belongs to the RibF family.

1123384:THY01S RS07455
gene id: 1123384:THY01S_RS07455
uniprot id: A0A0X1KP31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123384:THY01S RS05010
gene id: 1123384:THY01S_RS05010
uniprot id: A0A0X1KSH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1123384:THY01S RS03850
gene id: 1123384:THY01S_RS03850
uniprot id: A0A0X1KT31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1123384:THY01S RS02160
gene id: 1123384:THY01S_RS02160
uniprot id: A0A0X1KRI1
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS05635
gene id: 1123384:THY01S_RS05635
uniprot id: A0A0X1KPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1123384:THY01S RS06335
gene id: 1123384:THY01S_RS06335
uniprot id: A0A0X1KPX0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS09235
gene id: 1123384:THY01S_RS09235
uniprot id: A0A0X1KTC7
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02285
gene id: 1123384:THY01S_RS02285
uniprot id: A0A0X1KRE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1123384:THY01S RS01645
gene id: 1123384:THY01S_RS01645
uniprot id: A0A0X1KRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1123384:THY01S RS03835
gene id: 1123384:THY01S_RS03835
uniprot id: A0A0X1KSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1123384:THY01S RS10345
gene id: 1123384:THY01S_RS10345
uniprot id: A0A0X1KT72
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1123384:THY01S RS04815
gene id: 1123384:THY01S_RS04815
uniprot id: A0A0X1KSB4
names: Similarity
messages: Belongs to the asp23 family.

1123384:THY01S RS01025
gene id: 1123384:THY01S_RS01025
uniprot id: A0A0X1KR28
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1123384:THY01S RS05980
gene id: 1123384:THY01S_RS05980
uniprot id: A0A0X1KPY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1123384:THY01S RS02890
gene id: 1123384:THY01S_RS02890
uniprot id: A0A0X1KRS9
names: Similarity
messages: Belongs to the RutC family.

1123384:THY01S RS06975
gene id: 1123384:THY01S_RS06975
uniprot id: A0A0X1KPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1123384:THY01S RS08940
gene id: 1123384:THY01S_RS08940
uniprot id: A0A0X1KNN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1123384:THY01S RS00410
gene id: 1123384:THY01S_RS00410
uniprot id: A0A0X1KQK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS00325
gene id: 1123384:THY01S_RS00325
uniprot id: A0A0X1KQM2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1123384:THY01S RS00030
gene id: 1123384:THY01S_RS00030
uniprot id: A0A0X1KQI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS08690
gene id: 1123384:THY01S_RS08690
uniprot id: A0A0X1KNW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1123384:THY01S RS07510
gene id: 1123384:THY01S_RS07510
uniprot id: A0A0X1KP22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123384:THY01S RS07265
gene id: 1123384:THY01S_RS07265
uniprot id: A0A0X1KP76
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1123384:THY01S RS07750
gene id: 1123384:THY01S_RS07750
uniprot id: A0A0X1KQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS04935
gene id: 1123384:THY01S_RS04935
uniprot id: A0A0X1KSK1
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00840
gene id: 1123384:THY01S_RS00840
uniprot id: A0A0X1KQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1123384:THY01S RS03875
gene id: 1123384:THY01S_RS03875
uniprot id: A0A0X1KSZ4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1123384:THY01S RS06650
gene id: 1123384:THY01S_RS06650
uniprot id: A0A0X1KPM4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123384:THY01S RS01310
gene id: 1123384:THY01S_RS01310
uniprot id: A0A0X1KR73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1123384:THY01S RS03600
gene id: 1123384:THY01S_RS03600
uniprot id: A0A0X1KS86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1123384:THY01S RS07110
gene id: 1123384:THY01S_RS07110
uniprot id: A0A0X1KPE5
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS03725
gene id: 1123384:THY01S_RS03725
uniprot id: A0A0X1KSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1123384:THY01S RS06855
gene id: 1123384:THY01S_RS06855
uniprot id: A0A0X1KPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1123384:THY01S RS05200
gene id: 1123384:THY01S_RS05200
uniprot id: A0A0X1KQB4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1123384:THY01S RS05690
gene id: 1123384:THY01S_RS05690
uniprot id: A0A0X1KQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1123384:THY01S RS04550
gene id: 1123384:THY01S_RS04550
uniprot id: A0A0X1KSE1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1123384:THY01S RS01000
gene id: 1123384:THY01S_RS01000
uniprot id: A0A0X1KQU7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1123384:THY01S RS06120
gene id: 1123384:THY01S_RS06120
uniprot id: A0A0X1KPP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1123384:THY01S RS02570
gene id: 1123384:THY01S_RS02570
uniprot id: A0A0X1KRT0
names: Similarity
messages: Belongs to the Fur family.

1123384:THY01S RS00015
gene id: 1123384:THY01S_RS00015
uniprot id: A0A0X1KQL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS02600
gene id: 1123384:THY01S_RS02600
uniprot id: A0A0X1KRI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1123384:THY01S RS06620
gene id: 1123384:THY01S_RS06620
uniprot id: A0A0X1KPR1
names: Similarity
messages: Belongs to the YggT family.

1123384:THY01S RS06005
gene id: 1123384:THY01S_RS06005
uniprot id: A0A0X1KPS0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1123384:THY01S RS01435
gene id: 1123384:THY01S_RS01435
uniprot id: A0A0X1KTX9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02750
gene id: 1123384:THY01S_RS02750
uniprot id: A0A0X1KRT6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123384:THY01S RS07585
gene id: 1123384:THY01S_RS07585
uniprot id: A0A0X1KP87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1123384:THY01S RS03080
gene id: 1123384:THY01S_RS03080
uniprot id: A0A0X1KRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS03860
gene id: 1123384:THY01S_RS03860
uniprot id: A0A0X1KST6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123384:THY01S RS08710
gene id: 1123384:THY01S_RS08710
uniprot id: A0A0X1KNN7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123384:THY01S RS04470
gene id: 1123384:THY01S_RS04470
uniprot id: A0A0X1KSF4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1123384:THY01S RS09660
gene id: 1123384:THY01S_RS09660
uniprot id: A0A0X1KTI1
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06065
gene id: 1123384:THY01S_RS06065
uniprot id: A0A0X1KPS1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1123384:THY01S RS00555
gene id: 1123384:THY01S_RS00555
uniprot id: A0A0X1KQV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1123384:THY01S RS01420
gene id: 1123384:THY01S_RS01420
uniprot id: A0A0X1KR06
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS03795
gene id: 1123384:THY01S_RS03795
uniprot id: A0A0X1KS70
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00405
gene id: 1123384:THY01S_RS00405
uniprot id: A0A0X1KQI8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1123384:THY01S RS08790
gene id: 1123384:THY01S_RS08790
uniprot id: A0A0X1KTF9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1123384:THY01S RS01180
gene id: 1123384:THY01S_RS01180
uniprot id: A0A0X1KR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS02185
gene id: 1123384:THY01S_RS02185
uniprot id: A0A0X1KRC5
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS03335
gene id: 1123384:THY01S_RS03335
uniprot id: A0A0X1KS21
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1123384:THY01S RS08590
gene id: 1123384:THY01S_RS08590
uniprot id: A0A0X1KNQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS05015
gene id: 1123384:THY01S_RS05015
uniprot id: A0A0X1KSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1123384:THY01S RS04640
gene id: 1123384:THY01S_RS04640
uniprot id: A0A0X1KSL8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1123384:THY01S RS09715
gene id: 1123384:THY01S_RS09715
uniprot id: A0A0X1KT49
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06725
gene id: 1123384:THY01S_RS06725
uniprot id: A0A0X1KPP1
names: Similarity
messages: Belongs to the ArsC family.

1123384:THY01S RS07140
gene id: 1123384:THY01S_RS07140
uniprot id: A0A0X1KP89
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1123384:THY01S RS06420
gene id: 1123384:THY01S_RS06420
uniprot id: A0A0X1KPU9
names: Similarity
messages: Belongs to the peptidase S16 family.

1123384:THY01S RS00140
gene id: 1123384:THY01S_RS00140
uniprot id: A0A0X1KQJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123384:THY01S RS04705
gene id: 1123384:THY01S_RS04705
uniprot id: A0A0X1KSA8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123384:THY01S RS01170
gene id: 1123384:THY01S_RS01170
uniprot id: A0A0X1KTW0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1123384:THY01S RS06220
gene id: 1123384:THY01S_RS06220
uniprot id: A0A0X1KPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1123384:THY01S RS02430
gene id: 1123384:THY01S_RS02430
uniprot id: A0A0X1KRL6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1123384:THY01S RS07450
gene id: 1123384:THY01S_RS07450
uniprot id: A0A0X1KP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1123384:THY01S RS01065
gene id: 1123384:THY01S_RS01065
uniprot id: A0A0X1KQV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1123384:THY01S RS03500
gene id: 1123384:THY01S_RS03500
uniprot id: A0A0X1KRZ8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1123384:THY01S RS02425
gene id: 1123384:THY01S_RS02425
uniprot id: A0A0X1KRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1123384:THY01S RS07555
gene id: 1123384:THY01S_RS07555
uniprot id: A0A0X1KP30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1123384:THY01S RS00965
gene id: 1123384:THY01S_RS00965
uniprot id: A0A0X1KR18
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS05830
gene id: 1123384:THY01S_RS05830
uniprot id: A0A0X1KQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1123384:THY01S RS05465
gene id: 1123384:THY01S_RS05465
uniprot id: A0A0X1KQC4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1123384:THY01S RS09480
gene id: 1123384:THY01S_RS09480
uniprot id: A0A0X1KT87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS08245
gene id: 1123384:THY01S_RS08245
uniprot id: A0A0X1KP43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1123384:THY01S RS05720
gene id: 1123384:THY01S_RS05720
uniprot id: A0A0X1KQ33
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1123384:THY01S RS04825
gene id: 1123384:THY01S_RS04825
uniprot id: A0A0X1KS91
names: Similarity
messages: Belongs to the peptidase M24B family.

1123384:THY01S RS04715
gene id: 1123384:THY01S_RS04715
uniprot id: A0A0X1KSB2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123384:THY01S RS05185
gene id: 1123384:THY01S_RS05185
uniprot id: A0A0X1KQ67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1123384:THY01S RS02965
gene id: 1123384:THY01S_RS02965
uniprot id: A0A0X1KRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS03035
gene id: 1123384:THY01S_RS03035
uniprot id: A0A0X1KS42
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1123384:THY01S RS10350
gene id: 1123384:THY01S_RS10350
uniprot id: A0A0X1KT42
names: Similarity
messages: Belongs to the UPF0111 family.

1123384:THY01S RS08490
gene id: 1123384:THY01S_RS08490
uniprot id: A0A0X1KNV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1123384:THY01S RS07315
gene id: 1123384:THY01S_RS07315
uniprot id: A0A0X1KPD5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS07580
gene id: 1123384:THY01S_RS07580
uniprot id: A0A0X1KP65
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS02680
gene id: 1123384:THY01S_RS02680
uniprot id: A0A0X1KRY2
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06295
gene id: 1123384:THY01S_RS06295
uniprot id: A0A0X1KPX2
names: Similarity
messages: Belongs to the bacterial secretin family.

1123384:THY01S RS03465
gene id: 1123384:THY01S_RS03465
uniprot id: A0A0X1KS40
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS04060
gene id: 1123384:THY01S_RS04060
uniprot id: A0A0X1KSI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1123384:THY01S RS06695
gene id: 1123384:THY01S_RS06695
uniprot id: A0A0X1KPQ5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1123384:THY01S RS09995
gene id: 1123384:THY01S_RS09995
uniprot id: A0A0X1KTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1123384:THY01S RS08235
gene id: 1123384:THY01S_RS08235
uniprot id: A0A0X1KNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1123384:THY01S RS02335
gene id: 1123384:THY01S_RS02335
uniprot id: A0A0X1KRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS06125
gene id: 1123384:THY01S_RS06125
uniprot id: A0A0X1KPR2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1123384:THY01S RS02840
gene id: 1123384:THY01S_RS02840
uniprot id: A0A0X1KRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS03425
gene id: 1123384:THY01S_RS03425
uniprot id: A0A0X1KRY8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1123384:THY01S RS09505
gene id: 1123384:THY01S_RS09505
uniprot id: A0A0X1KTI2
names: Similarity
messages: Belongs to the Fur family.

1123384:THY01S RS08565
gene id: 1123384:THY01S_RS08565
uniprot id: A0A0X1KNX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1123384:THY01S RS08625
gene id: 1123384:THY01S_RS08625
uniprot id: A0A0X1KNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1123384:THY01S RS04560
gene id: 1123384:THY01S_RS04560
uniprot id: A0A0X1KSJ8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1123384:THY01S RS03125
gene id: 1123384:THY01S_RS03125
uniprot id: A0A0X1KS63
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1123384:THY01S RS08140
gene id: 1123384:THY01S_RS08140
uniprot id: A0A0X1KP62
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1123384:THY01S RS02500
gene id: 1123384:THY01S_RS02500
uniprot id: A0A0X1KRP7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123384:THY01S RS00730
gene id: 1123384:THY01S_RS00730
uniprot id: A0A0X1KQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS00820
gene id: 1123384:THY01S_RS00820
uniprot id: A0A0X1KQR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1123384:THY01S RS03765
gene id: 1123384:THY01S_RS03765
uniprot id: A0A0X1KS37
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS08125
gene id: 1123384:THY01S_RS08125
uniprot id: A0A0X1KNZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS01955
gene id: 1123384:THY01S_RS01955
uniprot id: A0A0X1KR89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS07515
gene id: 1123384:THY01S_RS07515
uniprot id: A0A0X1KPB6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1123384:THY01S RS09330
gene id: 1123384:THY01S_RS09330
uniprot id: A0A0X1KTF8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1123384:THY01S RS04455
gene id: 1123384:THY01S_RS04455
uniprot id: A0A0X1KSS9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1123384:THY01S RS09615
gene id: 1123384:THY01S_RS09615
uniprot id: A0A0X1KTB9
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

1123384:THY01S RS03285
gene id: 1123384:THY01S_RS03285
uniprot id: A0A0X1KRV0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123384:THY01S RS03260
gene id: 1123384:THY01S_RS03260
uniprot id: A0A0X1KU90
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123384:THY01S RS09725
gene id: 1123384:THY01S_RS09725
uniprot id: A0A0X1KTA0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1123384:THY01S RS04520
gene id: 1123384:THY01S_RS04520
uniprot id: A0A0X1KSQ3
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10540
gene id: 1123384:THY01S_RS10540
uniprot id: A0A0X1KSQ7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1123384:THY01S RS03970
gene id: 1123384:THY01S_RS03970
uniprot id: A0A0X1KST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS09350
gene id: 1123384:THY01S_RS09350
uniprot id: A0A0X1KTJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS08700
gene id: 1123384:THY01S_RS08700
uniprot id: A0A0X1KNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1123384:THY01S RS02235
gene id: 1123384:THY01S_RS02235
uniprot id: A0A0X1KRD8
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08630
gene id: 1123384:THY01S_RS08630
uniprot id: A0A0X1KNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1123384:THY01S RS08210
gene id: 1123384:THY01S_RS08210
uniprot id: A0A0X1KP15
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS05345
gene id: 1123384:THY01S_RS05345
uniprot id: A0A0X1KQ43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS08120
gene id: 1123384:THY01S_RS08120
uniprot id: A0A0X1KNX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1123384:THY01S RS06635
gene id: 1123384:THY01S_RS06635
uniprot id: A0A0X1KPJ0
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS07460
gene id: 1123384:THY01S_RS07460
uniprot id: A0A0X1KPC8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS09460
gene id: 1123384:THY01S_RS09460
uniprot id: A0A0X1KTI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1123384:THY01S RS05460
gene id: 1123384:THY01S_RS05460
uniprot id: A0A0X1KQ18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1123384:THY01S RS09755
gene id: 1123384:THY01S_RS09755
uniprot id: A0A0X1KT65
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1123384:THY01S RS10095
gene id: 1123384:THY01S_RS10095
uniprot id: A0A0X1KT27
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1123384:THY01S RS02045
gene id: 1123384:THY01S_RS02045
uniprot id: A0A0X1KRA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1123384:THY01S RS06270
gene id: 1123384:THY01S_RS06270
uniprot id: A0A0X1KPY2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1123384:THY01S RS09970
gene id: 1123384:THY01S_RS09970
uniprot id: A0A0X1KT05
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS00645
gene id: 1123384:THY01S_RS00645
uniprot id: A0A0X1KQP5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1123384:THY01S RS05155
gene id: 1123384:THY01S_RS05155
uniprot id: A0A0X1KS35
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS09495
gene id: 1123384:THY01S_RS09495
uniprot id: A0A0X1KTD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123384:THY01S RS08785
gene id: 1123384:THY01S_RS08785
uniprot id: A0A0X1KNQ7
names: Similarity
messages: Belongs to the UPF0235 family.

1123384:THY01S RS08485
gene id: 1123384:THY01S_RS08485
uniprot id: A0A0X1KNW3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1123384:THY01S RS01305
gene id: 1123384:THY01S_RS01305
uniprot id: A0A0X1KQZ0
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

1123384:THY01S RS01425
gene id: 1123384:THY01S_RS01425
uniprot id: A0A0X1KR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1123384:THY01S RS01440
gene id: 1123384:THY01S_RS01440
uniprot id: A0A0X1KR09
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1123384:THY01S RS10130
gene id: 1123384:THY01S_RS10130
uniprot id: A0A0X1KT07
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1123384:THY01S RS06645
gene id: 1123384:THY01S_RS06645
uniprot id: A0A0X1KPR5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1123384:THY01S RS06615
gene id: 1123384:THY01S_RS06615
uniprot id: A0A0X1KPR3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1123384:THY01S RS07065
gene id: 1123384:THY01S_RS07065
uniprot id: A0A0X1KPG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1123384:THY01S RS08720
gene id: 1123384:THY01S_RS08720
uniprot id: A0A0X1KNV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1123384:THY01S RS10070
gene id: 1123384:THY01S_RS10070
uniprot id: A0A0X1KT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1123384:THY01S RS08170
gene id: 1123384:THY01S_RS08170
uniprot id: A0A0X1KP49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1123384:THY01S RS08600
gene id: 1123384:THY01S_RS08600
uniprot id: A0A0X1KNT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1123384:THY01S RS06435
gene id: 1123384:THY01S_RS06435
uniprot id: A0A0X1KPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1123384:THY01S RS06745
gene id: 1123384:THY01S_RS06745
uniprot id: A0A0X1KPE6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1123384:THY01S RS05220
gene id: 1123384:THY01S_RS05220
uniprot id: A0A0X1KQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123384:THY01S RS02855
gene id: 1123384:THY01S_RS02855
uniprot id: A0A0X1KRN1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1123384:THY01S RS10285
gene id: 1123384:THY01S_RS10285
uniprot id: A0A0X1KSZ6
names: Similarity
messages: Belongs to the leucine-binding protein family.

1123384:THY01S RS06115
gene id: 1123384:THY01S_RS06115
uniprot id: A0A0X1KPY9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1123384:THY01S RS08155
gene id: 1123384:THY01S_RS08155
uniprot id: A0A0X1KP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS09365
gene id: 1123384:THY01S_RS09365
uniprot id: A0A0X1KTA7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1123384:THY01S RS07325
gene id: 1123384:THY01S_RS07325
uniprot id: A0A0X1KP79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1123384:THY01S RS03775
gene id: 1123384:THY01S_RS03775
uniprot id: A0A0X1KSB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1123384:THY01S RS08270
gene id: 1123384:THY01S_RS08270
uniprot id: A0A0X1KP28
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1123384:THY01S RS01325
gene id: 1123384:THY01S_RS01325
uniprot id: A0A0X1KR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1123384:THY01S RS00340
gene id: 1123384:THY01S_RS00340
uniprot id: A0A0X1KQW3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1123384:THY01S RS03595
gene id: 1123384:THY01S_RS03595
uniprot id: A0A0X1KRZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1123384:THY01S RS07530
gene id: 1123384:THY01S_RS07530
uniprot id: A0A0X1KP77
names: Similarity
messages: Belongs to the DtxR/MntR family.

1123384:THY01S RS01690
gene id: 1123384:THY01S_RS01690
uniprot id: A0A0X1KRE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1123384:THY01S RS09640
gene id: 1123384:THY01S_RS09640
uniprot id: A0A0X1KT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1123384:THY01S RS03175
gene id: 1123384:THY01S_RS03175
uniprot id: A0A0X1KS02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1123384:THY01S RS10140
gene id: 1123384:THY01S_RS10140
uniprot id: A0A0X1KSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS07310
gene id: 1123384:THY01S_RS07310
uniprot id: A0A0X1KPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1123384:THY01S RS05675
gene id: 1123384:THY01S_RS05675
uniprot id: A0A0X1KQ35
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1123384:THY01S RS04820
gene id: 1123384:THY01S_RS04820
uniprot id: A0A0X1KS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1123384:THY01S RS00130
gene id: 1123384:THY01S_RS00130
uniprot id: A0A0X1KQR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1123384:THY01S RS06055
gene id: 1123384:THY01S_RS06055
uniprot id: A0A0X1KQ01
names: Similarity
messages: Belongs to the histone deacetylase family.

1123384:THY01S RS01925
gene id: 1123384:THY01S_RS01925
uniprot id: A0A0X1KRL4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1123384:THY01S RS05515
gene id: 1123384:THY01S_RS05515
uniprot id: A0A0X1KQB1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123384:THY01S RS00170
gene id: 1123384:THY01S_RS00170
uniprot id: A0A0X1KQH0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1123384:THY01S RS09265
gene id: 1123384:THY01S_RS09265
uniprot id: A0A0X1KUK9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS07940
gene id: 1123384:THY01S_RS07940
uniprot id: A0A0X1KQK9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00360
gene id: 1123384:THY01S_RS00360
uniprot id: A0A0X1KQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08735
gene id: 1123384:THY01S_RS08735
uniprot id: A0A0X1KNR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123384:THY01S RS05600
gene id: 1123384:THY01S_RS05600
uniprot id: A0A0X1KQ46
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1123384:THY01S RS07230
gene id: 1123384:THY01S_RS07230
uniprot id: A0A0X1KPD0
names: Similarity
messages: Belongs to the UPF0145 family.

1123384:THY01S RS04100
gene id: 1123384:THY01S_RS04100
uniprot id: A0A0X1KSI8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1123384:THY01S RS08480
gene id: 1123384:THY01S_RS08480
uniprot id: A0A0X1KNV7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1123384:THY01S RS05105
gene id: 1123384:THY01S_RS05105
uniprot id: A0A0X1KS45
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1123384:THY01S RS02720
gene id: 1123384:THY01S_RS02720
uniprot id: A0A0X1KRM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1123384:THY01S RS00090
gene id: 1123384:THY01S_RS00090
uniprot id: A0A0X1KQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1123384:THY01S RS05755
gene id: 1123384:THY01S_RS05755
uniprot id: A0A0X1KPY6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1123384:THY01S RS00545
gene id: 1123384:THY01S_RS00545
uniprot id: A0A0X1KQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1123384:THY01S RS01850
gene id: 1123384:THY01S_RS01850
uniprot id: A0A0X1KR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS04655
gene id: 1123384:THY01S_RS04655
uniprot id: A0A0X1KSE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1123384:THY01S RS10175
gene id: 1123384:THY01S_RS10175
uniprot id: A0A0X1KT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1123384:THY01S RS01810
gene id: 1123384:THY01S_RS01810
uniprot id: A0A0X1KRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS10660
gene id: 1123384:THY01S_RS10660
uniprot id: A0A0X1KQC5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1123384:THY01S RS09445
gene id: 1123384:THY01S_RS09445
uniprot id: A0A0X1KTD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS06015
gene id: 1123384:THY01S_RS06015
uniprot id: A0A0X1KPT4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1123384:THY01S RS02725
gene id: 1123384:THY01S_RS02725
uniprot id: A0A0X1KRL5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1123384:THY01S RS03585
gene id: 1123384:THY01S_RS03585
uniprot id: A0A0X1KRY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS02935
gene id: 1123384:THY01S_RS02935
uniprot id: A0A0X1KUA7
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS01275
gene id: 1123384:THY01S_RS01275
uniprot id: A0A0X1KQY9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1123384:THY01S RS02140
gene id: 1123384:THY01S_RS02140
uniprot id: A0A0X1KRK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1123384:THY01S RS10080
gene id: 1123384:THY01S_RS10080
uniprot id: A0A0X1KSY1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1123384:THY01S RS09185
gene id: 1123384:THY01S_RS09185
uniprot id: A0A0X1KTQ9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06340
gene id: 1123384:THY01S_RS06340
uniprot id: A0A0X1KPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1123384:THY01S RS03935
gene id: 1123384:THY01S_RS03935
uniprot id: A0A0X1KSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS01380
gene id: 1123384:THY01S_RS01380
uniprot id: A0A0X1KR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1123384:THY01S RS09165
gene id: 1123384:THY01S_RS09165
uniprot id: A0A0X1KTE3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1123384:THY01S RS03415
gene id: 1123384:THY01S_RS03415
uniprot id: A0A0X1KRX4
names: Similarity
messages: Belongs to the UxaA family.

1123384:THY01S RS04390
gene id: 1123384:THY01S_RS04390
uniprot id: A0A0X1KSI4
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS09975
gene id: 1123384:THY01S_RS09975
uniprot id: A0A0X1KTE0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1123384:THY01S RS01290
gene id: 1123384:THY01S_RS01290
uniprot id: A0A0X1KQY8
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

1123384:THY01S RS03440
gene id: 1123384:THY01S_RS03440
uniprot id: A0A0X1KS66
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS01160
gene id: 1123384:THY01S_RS01160
uniprot id: A0A0X1KR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS07280
gene id: 1123384:THY01S_RS07280
uniprot id: A0A0X1KPG2
names: Similarity
messages: Belongs to the peptidase U62 family.

1123384:THY01S RS05920
gene id: 1123384:THY01S_RS05920
uniprot id: A0A0X1KQ44
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1123384:THY01S RS10580
gene id: 1123384:THY01S_RS10580
uniprot id: A0A0X1KT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS04955
gene id: 1123384:THY01S_RS04955
uniprot id: A0A0X1KSI5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123384:THY01S RS03460
gene id: 1123384:THY01S_RS03460
uniprot id: A0A0X1KS17
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1123384:THY01S RS01055
gene id: 1123384:THY01S_RS01055
uniprot id: A0A0X1KR10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1123384:THY01S RS10320
gene id: 1123384:THY01S_RS10320
uniprot id: A0A0X1KSU4
names: Similarity
messages: Belongs to the CutA family.

1123384:THY01S RS10620
gene id: 1123384:THY01S_RS10620
uniprot id: A0A0X1KQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1123384:THY01S RS05090
gene id: 1123384:THY01S_RS05090
uniprot id: A0A0X1KS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS07340
gene id: 1123384:THY01S_RS07340
uniprot id: A0A0X1KPF1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1123384:THY01S RS05805
gene id: 1123384:THY01S_RS05805
uniprot id: A0A0X1KPX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1123384:THY01S RS06175
gene id: 1123384:THY01S_RS06175
uniprot id: A0A0X1KPN9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1123384:THY01S RS09825
gene id: 1123384:THY01S_RS09825
uniprot id: A0A0X1KT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08175
gene id: 1123384:THY01S_RS08175
uniprot id: A0A0X1KNX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS08350
gene id: 1123384:THY01S_RS08350
uniprot id: A0A0X1KNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1123384:THY01S RS09060
gene id: 1123384:THY01S_RS09060
uniprot id: A0A0X1KNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1123384:THY01S RS06495
gene id: 1123384:THY01S_RS06495
uniprot id: A0A0X1KPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS10405
gene id: 1123384:THY01S_RS10405
uniprot id: A0A0X1KT30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123384:THY01S RS00085
gene id: 1123384:THY01S_RS00085
uniprot id: A0A0X1KQJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1123384:THY01S RS09610
gene id: 1123384:THY01S_RS09610
uniprot id: A0A0X1KTI7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123384:THY01S RS10530
gene id: 1123384:THY01S_RS10530
uniprot id: A0A0X1KST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08240
gene id: 1123384:THY01S_RS08240
uniprot id: A0A0X1KNW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1123384:THY01S RS09570
gene id: 1123384:THY01S_RS09570
uniprot id: A0A0X1KTH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1123384:THY01S RS01660
gene id: 1123384:THY01S_RS01660
uniprot id: A0A0X1KR43
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1123384:THY01S RS05630
gene id: 1123384:THY01S_RS05630
uniprot id: A0A0X1KQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1123384:THY01S RS08660
gene id: 1123384:THY01S_RS08660
uniprot id: A0A0X1KNS6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1123384:THY01S RS02625
gene id: 1123384:THY01S_RS02625
uniprot id: A0A0X1KRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123384:THY01S RS08110
gene id: 1123384:THY01S_RS08110
uniprot id: A0A0X1KP59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1123384:THY01S RS05935
gene id: 1123384:THY01S_RS05935
uniprot id: A0A0X1KQ16
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1123384:THY01S RS01700
gene id: 1123384:THY01S_RS01700
uniprot id: A0A0X1KRB4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1123384:THY01S RS08955
gene id: 1123384:THY01S_RS08955
uniprot id: A0A0X1KNR3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1123384:THY01S RS01610
gene id: 1123384:THY01S_RS01610
uniprot id: A0A0X1KRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1123384:THY01S RS08470
gene id: 1123384:THY01S_RS08470
uniprot id: A0A0X1KP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1123384:THY01S RS00290
gene id: 1123384:THY01S_RS00290
uniprot id: A0A0X1KQI7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1123384:THY01S RS09490
gene id: 1123384:THY01S_RS09490
uniprot id: A0A0X1KTL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1123384:THY01S RS08335
gene id: 1123384:THY01S_RS08335
uniprot id: A0A0X1KNT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1123384:THY01S RS04620
gene id: 1123384:THY01S_RS04620
uniprot id: A0A0X1KSI6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1123384:THY01S RS07030
gene id: 1123384:THY01S_RS07030
uniprot id: A0A0X1KTV6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1123384:THY01S RS06185
gene id: 1123384:THY01S_RS06185
uniprot id: A0A0X1KPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08050
gene id: 1123384:THY01S_RS08050
uniprot id: A0A0X1KP68
names: Similarity
messages: Belongs to the UPF0111 family.

1123384:THY01S RS07540
gene id: 1123384:THY01S_RS07540
uniprot id: A0A0X1KP92
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1123384:THY01S RS02405
gene id: 1123384:THY01S_RS02405
uniprot id: A0A0X1KRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1123384:THY01S RS07560
gene id: 1123384:THY01S_RS07560
uniprot id: A0A0X1KP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1123384:THY01S RS00080
gene id: 1123384:THY01S_RS00080
uniprot id: A0A0X1KQM0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS08575
gene id: 1123384:THY01S_RS08575
uniprot id: A0A0X1KNS0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1123384:THY01S RS05940
gene id: 1123384:THY01S_RS05940
uniprot id: A0A0X1KQ30
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1123384:THY01S RS01670
gene id: 1123384:THY01S_RS01670
uniprot id: A0A0X1KR44
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00305
gene id: 1123384:THY01S_RS00305
uniprot id: A0A0X1KQV1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1123384:THY01S RS05735
gene id: 1123384:THY01S_RS05735
uniprot id: A0A0X1KQ78
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1123384:THY01S RS04315
gene id: 1123384:THY01S_RS04315
uniprot id: A0A0X1KSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS02960
gene id: 1123384:THY01S_RS02960
uniprot id: A0A0X1KRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS04635
gene id: 1123384:THY01S_RS04635
uniprot id: A0A0X1KSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123384:THY01S RS01705
gene id: 1123384:THY01S_RS01705
uniprot id: A0A0X1KRJ4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1123384:THY01S RS10280
gene id: 1123384:THY01S_RS10280
uniprot id: A0A0X1KT12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1123384:THY01S RS00890
gene id: 1123384:THY01S_RS00890
uniprot id: A0A0X1KQT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1123384:THY01S RS01375
gene id: 1123384:THY01S_RS01375
uniprot id: A0A0X1KR01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1123384:THY01S RS04600
gene id: 1123384:THY01S_RS04600
uniprot id: A0A0X1KSF3
names: Similarity
messages: Belongs to the GARS family.

1123384:THY01S RS04830
gene id: 1123384:THY01S_RS04830
uniprot id: A0A0X1KSM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1123384:THY01S RS09410
gene id: 1123384:THY01S_RS09410
uniprot id: A0A0X1KTI4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1123384:THY01S RS00540
gene id: 1123384:THY01S_RS00540
uniprot id: A0A0X1KQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

1123384:THY01S RS10755
gene id: 1123384:THY01S_RS10755
uniprot id: A0A0X1KSE0
names: Similarity
messages: Belongs to the FlgM family.

1123384:THY01S RS00865
gene id: 1123384:THY01S_RS00865
uniprot id: A0A0X1KQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS06705
gene id: 1123384:THY01S_RS06705
uniprot id: A0A0X1KPK5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1123384:THY01S RS10410
gene id: 1123384:THY01S_RS10410
uniprot id: A0A0X1KST1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123384:THY01S RS03475
gene id: 1123384:THY01S_RS03475
uniprot id: A0A0X1KRY3
names: Similarity
messages: Belongs to the carbamate kinase family.

1123384:THY01S RS07055
gene id: 1123384:THY01S_RS07055
uniprot id: A0A0X1KPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08585
gene id: 1123384:THY01S_RS08585
uniprot id: A0A0X1KTL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1123384:THY01S RS10820
gene id: 1123384:THY01S_RS10820
uniprot id: A0A0X1KTI3
names: Similarity
messages: Belongs to the bacterial secretin family.

1123384:THY01S RS04580
gene id: 1123384:THY01S_RS04580
uniprot id: A0A0X1KSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS01365
gene id: 1123384:THY01S_RS01365
uniprot id: A0A0X1KQZ8
names: Similarity
messages: Belongs to the peptidase S58 family.

1123384:THY01S RS07120
gene id: 1123384:THY01S_RS07120
uniprot id: A0A0X1KPE8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1123384:THY01S RS01545
gene id: 1123384:THY01S_RS01545
uniprot id: A0A0X1KR25
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1123384:THY01S RS03680
gene id: 1123384:THY01S_RS03680
uniprot id: A0A0X1KU99
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08095
gene id: 1123384:THY01S_RS08095
uniprot id: A0A0X1KP33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1123384:THY01S RS09540
gene id: 1123384:THY01S_RS09540
uniprot id: A0A0X1KT77
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1123384:THY01S RS07160
gene id: 1123384:THY01S_RS07160
uniprot id: A0A0X1KPH6
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1123384:THY01S RS01855
gene id: 1123384:THY01S_RS01855
uniprot id: A0A0X1KR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08415
gene id: 1123384:THY01S_RS08415
uniprot id: A0A0X1KNX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS05835
gene id: 1123384:THY01S_RS05835
uniprot id: A0A0X1KQ36
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1123384:THY01S RS05885
gene id: 1123384:THY01S_RS05885
uniprot id: A0A0X1KQ24
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1123384:THY01S RS08200
gene id: 1123384:THY01S_RS08200
uniprot id: A0A0X1KP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1123384:THY01S RS09635
gene id: 1123384:THY01S_RS09635
uniprot id: A0A0X1KTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1123384:THY01S RS00560
gene id: 1123384:THY01S_RS00560
uniprot id: A0A0X1KQR0
names: Similarity
messages: Belongs to the GSP E family.

1123384:THY01S RS10625
gene id: 1123384:THY01S_RS10625
uniprot id: A0A0X1KQK1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1123384:THY01S RS08500
gene id: 1123384:THY01S_RS08500
uniprot id: A0A0X1KNZ2
names: Similarity
messages: Belongs to the fabD family.

1123384:THY01S RS05115
gene id: 1123384:THY01S_RS05115
uniprot id: A0A0X1KSA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1123384:THY01S RS04495
gene id: 1123384:THY01S_RS04495
uniprot id: A0A0X1KST0
names: Similarity
messages: Belongs to the UPF0173 family.

1123384:THY01S RS06405
gene id: 1123384:THY01S_RS06405
uniprot id: A0A0X1KPS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1123384:THY01S RS05740
gene id: 1123384:THY01S_RS05740
uniprot id: A0A0X1KQ65
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS00690
gene id: 1123384:THY01S_RS00690
uniprot id: A0A0X1KQV2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS04615
gene id: 1123384:THY01S_RS04615
uniprot id: A0A0X1KSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1123384:THY01S RS10610
gene id: 1123384:THY01S_RS10610
uniprot id: A0A0X1KQD1
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1123384:THY01S RS09075
gene id: 1123384:THY01S_RS09075
uniprot id: A0A0X1KNL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1123384:THY01S RS00905
gene id: 1123384:THY01S_RS00905
uniprot id: A0A0X1KR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS02435
gene id: 1123384:THY01S_RS02435
uniprot id: A0A0X1KRN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS07320
gene id: 1123384:THY01S_RS07320
uniprot id: A0A0X1KP55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1123384:THY01S RS09875
gene id: 1123384:THY01S_RS09875
uniprot id: A0A0X1KTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS05330
gene id: 1123384:THY01S_RS05330
uniprot id: A0A0X1KQE7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1123384:THY01S RS04105
gene id: 1123384:THY01S_RS04105
uniprot id: A0A0X1KSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1123384:THY01S RS02020
gene id: 1123384:THY01S_RS02020
uniprot id: A0A0X1KRG3
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1123384:THY01S RS10000
gene id: 1123384:THY01S_RS10000
uniprot id: A0A0X1KTD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1123384:THY01S RS05130
gene id: 1123384:THY01S_RS05130
uniprot id: A0A0X1KSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00460
gene id: 1123384:THY01S_RS00460
uniprot id: A0A0X1KQL7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1123384:THY01S RS05485
gene id: 1123384:THY01S_RS05485
uniprot id: A0A0X1KQB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1123384:THY01S RS07880
gene id: 1123384:THY01S_RS07880
uniprot id: A0A0X1KQB2
names: Similarity
messages: Belongs to the peptidase S8 family.

1123384:THY01S RS06225
gene id: 1123384:THY01S_RS06225
uniprot id: A0A0X1KPW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS05665
gene id: 1123384:THY01S_RS05665
uniprot id: A0A0X1KQ92
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06595
gene id: 1123384:THY01S_RS06595
uniprot id: A0A0X1KPN4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1123384:THY01S RS09015
gene id: 1123384:THY01S_RS09015
uniprot id: A0A0X1KNM8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1123384:THY01S RS02735
gene id: 1123384:THY01S_RS02735
uniprot id: A0A0X1KRZ1
names: Similarity
messages: Belongs to the MotB family.

1123384:THY01S RS03845
gene id: 1123384:THY01S_RS03845
uniprot id: A0A0X1KSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08330
gene id: 1123384:THY01S_RS08330
uniprot id: A0A0X1KP17
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1123384:THY01S RS00240
gene id: 1123384:THY01S_RS00240
uniprot id: A0A0X1KQH1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123384:THY01S RS06070
gene id: 1123384:THY01S_RS06070
uniprot id: A0A0X1KPT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1123384:THY01S RS05385
gene id: 1123384:THY01S_RS05385
uniprot id: A0A0X1KQD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1123384:THY01S RS04730
gene id: 1123384:THY01S_RS04730
uniprot id: A0A0X1KSG9
names: Similarity
messages: Belongs to the Skp family.

1123384:THY01S RS04515
gene id: 1123384:THY01S_RS04515
uniprot id: A0A0X1KSJ0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1123384:THY01S RS00850
gene id: 1123384:THY01S_RS00850
uniprot id: A0A0X1KR03
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1123384:THY01S RS09625
gene id: 1123384:THY01S_RS09625
uniprot id: A0A0X1KTG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1123384:THY01S RS00985
gene id: 1123384:THY01S_RS00985
uniprot id: A0A0X1KQY5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1123384:THY01S RS06245
gene id: 1123384:THY01S_RS06245
uniprot id: A0A0X1KPP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS06550
gene id: 1123384:THY01S_RS06550
uniprot id: A0A0X1KPQ6
names: Similarity
messages: Belongs to the class-I fumarase family.

1123384:THY01S RS05025
gene id: 1123384:THY01S_RS05025
uniprot id: A0A0X1KU82
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1123384:THY01S RS06010
gene id: 1123384:THY01S_RS06010
uniprot id: A0A0X1KPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1123384:THY01S RS06850
gene id: 1123384:THY01S_RS06850
uniprot id: A0A0X1KPE9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1123384:THY01S RS04335
gene id: 1123384:THY01S_RS04335
uniprot id: A0A0X1KSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1123384:THY01S RS01300
gene id: 1123384:THY01S_RS01300
uniprot id: A0A0X1KU08
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

1123384:THY01S RS09575
gene id: 1123384:THY01S_RS09575
uniprot id: A0A0X1KTJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1123384:THY01S RS04770
gene id: 1123384:THY01S_RS04770
uniprot id: A0A0X1KSA5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1123384:THY01S RS00895
gene id: 1123384:THY01S_RS00895
uniprot id: A0A0X1KQT1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS06885
gene id: 1123384:THY01S_RS06885
uniprot id: A0A0X1KTT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS06755
gene id: 1123384:THY01S_RS06755
uniprot id: A0A0X1KPK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1123384:THY01S RS01585
gene id: 1123384:THY01S_RS01585
uniprot id: A0A0X1KRH4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1123384:THY01S RS08430
gene id: 1123384:THY01S_RS08430
uniprot id: A0A0X1KNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08665
gene id: 1123384:THY01S_RS08665
uniprot id: A0A0X1KNT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1123384:THY01S RS04525
gene id: 1123384:THY01S_RS04525
uniprot id: A0A0X1KSR9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02410
gene id: 1123384:THY01S_RS02410
uniprot id: A0A0X1KRQ0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1123384:THY01S RS07400
gene id: 1123384:THY01S_RS07400
uniprot id: A0A0X1KP60
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1123384:THY01S RS09440
gene id: 1123384:THY01S_RS09440
uniprot id: A0A0X1KTF3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1123384:THY01S RS08855
gene id: 1123384:THY01S_RS08855
uniprot id: A0A0X1KNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1123384:THY01S RS10570
gene id: 1123384:THY01S_RS10570
uniprot id: A0A0X1KSU6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1123384:THY01S RS03010
gene id: 1123384:THY01S_RS03010
uniprot id: A0A0X1KRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS04460
gene id: 1123384:THY01S_RS04460
uniprot id: A0A0X1KSQ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1123384:THY01S RS06750
gene id: 1123384:THY01S_RS06750
uniprot id: A0A0X1KPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1123384:THY01S RS03385
gene id: 1123384:THY01S_RS03385
uniprot id: A0A0X1KS07
names: Similarity
messages: Belongs to the UPF0045 family.

1123384:THY01S RS10015
gene id: 1123384:THY01S_RS10015
uniprot id: A0A0X1KT26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1123384:THY01S RS03705
gene id: 1123384:THY01S_RS03705
uniprot id: A0A0X1KS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1123384:THY01S RS08900
gene id: 1123384:THY01S_RS08900
uniprot id: A0A0X1KNS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1123384:THY01S RS10445
gene id: 1123384:THY01S_RS10445
uniprot id: A0A0X1KT29
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1123384:THY01S RS05960
gene id: 1123384:THY01S_RS05960
uniprot id: A0A0X1KPU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1123384:THY01S RS07285
gene id: 1123384:THY01S_RS07285
uniprot id: A0A0X1KPB7
names: Similarity
messages: Belongs to the peptidase U62 family.

1123384:THY01S RS11170
gene id: 1123384:THY01S_RS11170
uniprot id: A0A0X1KSY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1123384:THY01S RS09070
gene id: 1123384:THY01S_RS09070
uniprot id: A0A0X1KNQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1123384:THY01S RS00135
gene id: 1123384:THY01S_RS00135
uniprot id: A0A0X1KQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1123384:THY01S RS04795
gene id: 1123384:THY01S_RS04795
uniprot id: A0A0X1KSK0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1123384:THY01S RS07630
gene id: 1123384:THY01S_RS07630
uniprot id: A0A0X1KP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS03750
gene id: 1123384:THY01S_RS03750
uniprot id: A0A0X1KSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1123384:THY01S RS04125
gene id: 1123384:THY01S_RS04125
uniprot id: A0A0X1KSV2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1123384:THY01S RS05150
gene id: 1123384:THY01S_RS05150
uniprot id: A0A0X1KS31
names: Function
names: Subunit
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.

1123384:THY01S RS02460
gene id: 1123384:THY01S_RS02460
uniprot id: A0A0X1KRH6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1123384:THY01S RS10145
gene id: 1123384:THY01S_RS10145
uniprot id: A0A0X1KTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08135
gene id: 1123384:THY01S_RS08135
uniprot id: A0A0X1KNX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1123384:THY01S RS06625
gene id: 1123384:THY01S_RS06625
uniprot id: A0A0X1KPH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS00855
gene id: 1123384:THY01S_RS00855
uniprot id: A0A0X1KQW4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS04875
gene id: 1123384:THY01S_RS04875
uniprot id: A0A0X1KS84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1123384:THY01S RS05530
gene id: 1123384:THY01S_RS05530
uniprot id: A0A0X1KQ82
names: Subcellular Location Annotation
messages: Cytoplasm

1123384:THY01S RS06740
gene id: 1123384:THY01S_RS06740
uniprot id: A0A0X1KPG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1123384:THY01S RS10615
gene id: 1123384:THY01S_RS10615
uniprot id: A0A0X1KQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1123384:THY01S RS09150
gene id: 1123384:THY01S_RS09150
uniprot id: A0A0X1KTE1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1123384:THY01S RS07085
gene id: 1123384:THY01S_RS07085
uniprot id: A0A0X1KPB2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1123384:THY01S RS07830
gene id: 1123384:THY01S_RS07830
uniprot id: A0A0X1KTT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS05540
gene id: 1123384:THY01S_RS05540
uniprot id: A0A0X1KQ94
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1123384:THY01S RS08410
gene id: 1123384:THY01S_RS08410
uniprot id: A0A0X1KP12
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10365
gene id: 1123384:THY01S_RS10365
uniprot id: A0A0X1KST8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1123384:THY01S RS07375
gene id: 1123384:THY01S_RS07375
uniprot id: A0A0X1KTV4
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00945
gene id: 1123384:THY01S_RS00945
uniprot id: A0A0X1KQU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1123384:THY01S RS04510
gene id: 1123384:THY01S_RS04510
uniprot id: A0A0X1KSK9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1123384:THY01S RS03165
gene id: 1123384:THY01S_RS03165
uniprot id: A0A0X1KS33
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123384:THY01S RS07080
gene id: 1123384:THY01S_RS07080
uniprot id: A0A0X1KP94
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1123384:THY01S RS00790
gene id: 1123384:THY01S_RS00790
uniprot id: A0A0X1KQY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1123384:THY01S RS02125
gene id: 1123384:THY01S_RS02125
uniprot id: A0A0X1KRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS03730
gene id: 1123384:THY01S_RS03730
uniprot id: A0A0X1KS58
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123384:THY01S RS05225
gene id: 1123384:THY01S_RS05225
uniprot id: A0A0X1KQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1123384:THY01S RS04535
gene id: 1123384:THY01S_RS04535
uniprot id: A0A0X1KSE4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1123384:THY01S RS06460
gene id: 1123384:THY01S_RS06460
uniprot id: A0A0X1KPM0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1123384:THY01S RS01890
gene id: 1123384:THY01S_RS01890
uniprot id: A0A0X1KRL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1123384:THY01S RS03255
gene id: 1123384:THY01S_RS03255
uniprot id: A0A0X1KU76
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1123384:THY01S RS08310
gene id: 1123384:THY01S_RS08310
uniprot id: A0A0X1KNY8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1123384:THY01S RS05510
gene id: 1123384:THY01S_RS05510
uniprot id: A0A0X1KQ08
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1123384:THY01S RS05245
gene id: 1123384:THY01S_RS05245
uniprot id: A0A0X1KQG5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1123384:THY01S RS05680
gene id: 1123384:THY01S_RS05680
uniprot id: A0A0X1KQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1123384:THY01S RS10005
gene id: 1123384:THY01S_RS10005
uniprot id: A0A0X1KTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1123384:THY01S RS03880
gene id: 1123384:THY01S_RS03880
uniprot id: A0A0X1KSP1
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08230
gene id: 1123384:THY01S_RS08230
uniprot id: A0A0X1KNX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1123384:THY01S RS10765
gene id: 1123384:THY01S_RS10765
uniprot id: A0A0X1KUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1123384:THY01S RS10420
gene id: 1123384:THY01S_RS10420
uniprot id: A0A0X1KSS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1123384:THY01S RS06640
gene id: 1123384:THY01S_RS06640
uniprot id: A0A0X1KPH1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1123384:THY01S RS02820
gene id: 1123384:THY01S_RS02820
uniprot id: A0A0X1KRM2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1123384:THY01S RS04265
gene id: 1123384:THY01S_RS04265
uniprot id: A0A0X1KT00
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1123384:THY01S RS07185
gene id: 1123384:THY01S_RS07185
uniprot id: A0A0X1KPF6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1123384:THY01S RS01730
gene id: 1123384:THY01S_RS01730
uniprot id: A0A0X1KTW8
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS07095
gene id: 1123384:THY01S_RS07095
uniprot id: A0A0X1KP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS10020
gene id: 1123384:THY01S_RS10020
uniprot id: A0A0X1KSZ8
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS01745
gene id: 1123384:THY01S_RS01745
uniprot id: A0A0X1KU23
names: Similarity
messages: Belongs to the DapA family.

1123384:THY01S RS10665
gene id: 1123384:THY01S_RS10665
uniprot id: A0A0X1KQD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1123384:THY01S RS03215
gene id: 1123384:THY01S_RS03215
uniprot id: A0A0X1KS44
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1123384:THY01S RS03615
gene id: 1123384:THY01S_RS03615
uniprot id: A0A0X1KS38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS02835
gene id: 1123384:THY01S_RS02835
uniprot id: A0A0X1KRX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1123384:THY01S RS08555
gene id: 1123384:THY01S_RS08555
uniprot id: A0A0X1KNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1123384:THY01S RS04275
gene id: 1123384:THY01S_RS04275
uniprot id: A0A0X1KU88
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08065
gene id: 1123384:THY01S_RS08065
uniprot id: A0A0X1KNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1123384:THY01S RS09360
gene id: 1123384:THY01S_RS09360
uniprot id: A0A0X1KTD5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1123384:THY01S RS00930
gene id: 1123384:THY01S_RS00930
uniprot id: A0A0X1KQT7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123384:THY01S RS04755
gene id: 1123384:THY01S_RS04755
uniprot id: A0A0X1KUI4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1123384:THY01S RS02980
gene id: 1123384:THY01S_RS02980
uniprot id: A0A0X1KRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1123384:THY01S RS05990
gene id: 1123384:THY01S_RS05990
uniprot id: A0A0X1KQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1123384:THY01S RS03565
gene id: 1123384:THY01S_RS03565
uniprot id: A0A0X1KS51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1123384:THY01S RS00875
gene id: 1123384:THY01S_RS00875
uniprot id: A0A0X1KQS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1123384:THY01S RS08000
gene id: 1123384:THY01S_RS08000
uniprot id: A0A0X1KQA6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1123384:THY01S RS05260
gene id: 1123384:THY01S_RS05260
uniprot id: A0A0X1KQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS02575
gene id: 1123384:THY01S_RS02575
uniprot id: A0A0X1KU96
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10125
gene id: 1123384:THY01S_RS10125
uniprot id: A0A0X1KUD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1123384:THY01S RS10675
gene id: 1123384:THY01S_RS10675
uniprot id: A0A0X1KQC2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1123384:THY01S RS05975
gene id: 1123384:THY01S_RS05975
uniprot id: A0A0X1KQ32
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1123384:THY01S RS09735
gene id: 1123384:THY01S_RS09735
uniprot id: A0A0X1KTE4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1123384:THY01S RS00470
gene id: 1123384:THY01S_RS00470
uniprot id: A0A0X1KQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1123384:THY01S RS02315
gene id: 1123384:THY01S_RS02315
uniprot id: A0A0X1KRP1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1123384:THY01S RS05995
gene id: 1123384:THY01S_RS05995
uniprot id: A0A0X1KQ20
names: Subcellular Location Annotation
messages: Cytoplasm

1123384:THY01S RS07075
gene id: 1123384:THY01S_RS07075
uniprot id: A0A0X1KPH9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1123384:THY01S RS08715
gene id: 1123384:THY01S_RS08715
uniprot id: A0A0X1KNN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1123384:THY01S RS09135
gene id: 1123384:THY01S_RS09135
uniprot id: A0A0X1KTP0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1123384:THY01S RS09190
gene id: 1123384:THY01S_RS09190
uniprot id: A0A0X1KTJ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1123384:THY01S RS03605
gene id: 1123384:THY01S_RS03605
uniprot id: A0A0X1KSC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1123384:THY01S RS00535
gene id: 1123384:THY01S_RS00535
uniprot id: A0A0X1KTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1123384:THY01S RS02290
gene id: 1123384:THY01S_RS02290
uniprot id: A0A0X1KRE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1123384:THY01S RS07180
gene id: 1123384:THY01S_RS07180
uniprot id: A0A0X1KPF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1123384:THY01S RS02535
gene id: 1123384:THY01S_RS02535
uniprot id: A0A0X1KRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS06800
gene id: 1123384:THY01S_RS06800
uniprot id: A0A0X1KPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1123384:THY01S RS08130
gene id: 1123384:THY01S_RS08130
uniprot id: A0A0X1KNZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1123384:THY01S RS00270
gene id: 1123384:THY01S_RS00270
uniprot id: A0A0X1KQN1
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS11135
gene id: 1123384:THY01S_RS11135
uniprot id: A0A0X1KSU3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1123384:THY01S RS03940
gene id: 1123384:THY01S_RS03940
uniprot id: A0A0X1KSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00640
gene id: 1123384:THY01S_RS00640
uniprot id: A0A0X1KQN8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1123384:THY01S RS04370
gene id: 1123384:THY01S_RS04370
uniprot id: A0A0X1KST9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1123384:THY01S RS04800
gene id: 1123384:THY01S_RS04800
uniprot id: A0A0X1KSL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1123384:THY01S RS05730
gene id: 1123384:THY01S_RS05730
uniprot id: A0A0X1KQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS00685
gene id: 1123384:THY01S_RS00685
uniprot id: A0A0X1KQT0
names: Similarity
messages: Belongs to the serpin family.

1123384:THY01S RS01930
gene id: 1123384:THY01S_RS01930
uniprot id: A0A0X1KRI2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1123384:THY01S RS09785
gene id: 1123384:THY01S_RS09785
uniprot id: A0A0X1KT91
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1123384:THY01S RS09485
gene id: 1123384:THY01S_RS09485
uniprot id: A0A0X1KT92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS10300
gene id: 1123384:THY01S_RS10300
uniprot id: A0A0X1KT51
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS00755
gene id: 1123384:THY01S_RS00755
uniprot id: A0A0X1KQW1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1123384:THY01S RS01650
gene id: 1123384:THY01S_RS01650
uniprot id: A0A0X1KRI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1123384:THY01S RS09545
gene id: 1123384:THY01S_RS09545
uniprot id: A0A0X1KT82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1123384:THY01S RS00785
gene id: 1123384:THY01S_RS00785
uniprot id: A0A0X1KQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08520
gene id: 1123384:THY01S_RS08520
uniprot id: A0A0X1KNR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1123384:THY01S RS07475
gene id: 1123384:THY01S_RS07475
uniprot id: A0A0X1KP91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1123384:THY01S RS05405
gene id: 1123384:THY01S_RS05405
uniprot id: A0A0X1KQ47
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1123384:THY01S RS05605
gene id: 1123384:THY01S_RS05605
uniprot id: A0A0X1KQ72
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1123384:THY01S RS02635
gene id: 1123384:THY01S_RS02635
uniprot id: A0A0X1KRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123384:THY01S RS08455
gene id: 1123384:THY01S_RS08455
uniprot id: A0A0X1KTG8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123384:THY01S RS03090
gene id: 1123384:THY01S_RS03090
uniprot id: A0A0X1KRT7
names: Similarity
messages: Belongs to the peptidase M20A family.

1123384:THY01S RS03700
gene id: 1123384:THY01S_RS03700
uniprot id: A0A0X1KS09
names: Similarity
messages: Belongs to the bacterial flagellin family.

1123384:THY01S RS06520
gene id: 1123384:THY01S_RS06520
uniprot id: A0A0X1KPL0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS09355
gene id: 1123384:THY01S_RS09355
uniprot id: A0A0X1KTB3
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10630
gene id: 1123384:THY01S_RS10630
uniprot id: A0A0X1KQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1123384:THY01S RS03710
gene id: 1123384:THY01S_RS03710
uniprot id: A0A0X1KS10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1123384:THY01S RS01570
gene id: 1123384:THY01S_RS01570
uniprot id: A0A0X1KRC1
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1123384:THY01S RS05370
gene id: 1123384:THY01S_RS05370
uniprot id: A0A0X1KQ86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1123384:THY01S RS06470
gene id: 1123384:THY01S_RS06470
uniprot id: A0A0X1KPV1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1123384:THY01S RS08595
gene id: 1123384:THY01S_RS08595
uniprot id: A0A0X1KNY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1123384:THY01S RS00770
gene id: 1123384:THY01S_RS00770
uniprot id: A0A0X1KQQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS00040
gene id: 1123384:THY01S_RS00040
uniprot id: A0A0X1KQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1123384:THY01S RS02595
gene id: 1123384:THY01S_RS02595
uniprot id: A0A0X1KRI8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1123384:THY01S RS05945
gene id: 1123384:THY01S_RS05945
uniprot id: A0A0X1KQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1123384:THY01S RS05710
gene id: 1123384:THY01S_RS05710
uniprot id: A0A0X1KPX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1123384:THY01S RS04840
gene id: 1123384:THY01S_RS04840
uniprot id: A0A0X1KSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08615
gene id: 1123384:THY01S_RS08615
uniprot id: A0A0X1KNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1123384:THY01S RS00010
gene id: 1123384:THY01S_RS00010
uniprot id: A0A0X1KQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1123384:THY01S RS00900
gene id: 1123384:THY01S_RS00900
uniprot id: A0A0X1KR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08180
gene id: 1123384:THY01S_RS08180
uniprot id: A0A0X1KNY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1123384:THY01S RS06095
gene id: 1123384:THY01S_RS06095
uniprot id: A0A0X1KPY1
names: Similarity
messages: Belongs to the RecJ family.

1123384:THY01S RS09080
gene id: 1123384:THY01S_RS09080
uniprot id: A0A0X1KNM5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1123384:THY01S RS02590
gene id: 1123384:THY01S_RS02590
uniprot id: A0A0X1KRX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1123384:THY01S RS01230
gene id: 1123384:THY01S_RS01230
uniprot id: A0A0X1KR65
names: Similarity
messages: Belongs to the XFP family.

1123384:THY01S RS01615
gene id: 1123384:THY01S_RS01615
uniprot id: A0A0X1KRG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS05610
gene id: 1123384:THY01S_RS05610
uniprot id: A0A0X1KQ98
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1123384:THY01S RS00220
gene id: 1123384:THY01S_RS00220
uniprot id: A0A0X1KQU2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1123384:THY01S RS02795
gene id: 1123384:THY01S_RS02795
uniprot id: A0A0X1KU86
names: Similarity
messages: Belongs to the creatininase superfamily.

1123384:THY01S RS00735
gene id: 1123384:THY01S_RS00735
uniprot id: A0A0X1KQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS05870
gene id: 1123384:THY01S_RS05870
uniprot id: A0A0X1KQ52
names: Similarity
messages: Belongs to the peptidase S8 family.

1123384:THY01S RS07255
gene id: 1123384:THY01S_RS07255
uniprot id: A0A0X1KP88
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1123384:THY01S RS08075
gene id: 1123384:THY01S_RS08075
uniprot id: A0A0X1KP01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1123384:THY01S RS08190
gene id: 1123384:THY01S_RS08190
uniprot id: A0A0X1KNX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1123384:THY01S RS10030
gene id: 1123384:THY01S_RS10030
uniprot id: A0A0X1KTD0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123384:THY01S RS04310
gene id: 1123384:THY01S_RS04310
uniprot id: A0A0X1KSH3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS04115
gene id: 1123384:THY01S_RS04115
uniprot id: A0A0X1KSU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS01815
gene id: 1123384:THY01S_RS01815
uniprot id: A0A0X1KRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS09145
gene id: 1123384:THY01S_RS09145
uniprot id: A0A0X1KTM2
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08150
gene id: 1123384:THY01S_RS08150
uniprot id: A0A0X1KP21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1123384:THY01S RS04810
gene id: 1123384:THY01S_RS04810
uniprot id: A0A0X1KS87
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1123384:THY01S RS04485
gene id: 1123384:THY01S_RS04485
uniprot id: A0A0X1KSF1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123384:THY01S RS06980
gene id: 1123384:THY01S_RS06980
uniprot id: A0A0X1KPC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

1123384:THY01S RS03635
gene id: 1123384:THY01S_RS03635
uniprot id: A0A0X1KS05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1123384:THY01S RS08655
gene id: 1123384:THY01S_RS08655
uniprot id: A0A0X1KNW8
names: Similarity
messages: Belongs to the acylphosphatase family.

1123384:THY01S RS05435
gene id: 1123384:THY01S_RS05435
uniprot id: A0A0X1KQC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1123384:THY01S RS04595
gene id: 1123384:THY01S_RS04595
uniprot id: A0A0X1KSD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1123384:THY01S RS01860
gene id: 1123384:THY01S_RS01860
uniprot id: A0A0X1KR75
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1123384:THY01S RS05135
gene id: 1123384:THY01S_RS05135
uniprot id: A0A0X1KSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08275
gene id: 1123384:THY01S_RS08275
uniprot id: A0A0X1KNU9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1123384:THY01S RS09910
gene id: 1123384:THY01S_RS09910
uniprot id: A0A0X1KT15
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS03675
gene id: 1123384:THY01S_RS03675
uniprot id: A0A0X1KS72
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1123384:THY01S RS08420
gene id: 1123384:THY01S_RS08420
uniprot id: A0A0X1KNX3
names: Subcellular Location Annotation
messages: Cytoplasm

1123384:THY01S RS04885
gene id: 1123384:THY01S_RS04885
uniprot id: A0A0X1KSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS05365
gene id: 1123384:THY01S_RS05365
uniprot id: A0A0X1KQ89
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1123384:THY01S RS00565
gene id: 1123384:THY01S_RS00565
uniprot id: A0A0X1KQT4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1123384:THY01S RS08380
gene id: 1123384:THY01S_RS08380
uniprot id: A0A0X1KP11
names: Similarity
messages: Belongs to the CinA family.

1123384:THY01S RS05815
gene id: 1123384:THY01S_RS05815
uniprot id: A0A0X1KPV9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123384:THY01S RS04095
gene id: 1123384:THY01S_RS04095
uniprot id: A0A0X1KSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1123384:THY01S RS01370
gene id: 1123384:THY01S_RS01370
uniprot id: A0A0X1KR02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1123384:THY01S RS01080
gene id: 1123384:THY01S_RS01080
uniprot id: A0A0X1KQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS07390
gene id: 1123384:THY01S_RS07390
uniprot id: A0A0X1KTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08255
gene id: 1123384:THY01S_RS08255
uniprot id: A0A0X1KNZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1123384:THY01S RS07175
gene id: 1123384:THY01S_RS07175
uniprot id: A0A0X1KPD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1123384:THY01S RS02620
gene id: 1123384:THY01S_RS02620
uniprot id: A0A0X1KRT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123384:THY01S RS02730
gene id: 1123384:THY01S_RS02730
uniprot id: A0A0X1KRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1123384:THY01S RS08745
gene id: 1123384:THY01S_RS08745
uniprot id: A0A0X1KNV1
names: Similarity
messages: Belongs to the peptidase U62 family.

1123384:THY01S RS05335
gene id: 1123384:THY01S_RS05335
uniprot id: A0A0X1KQD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1123384:THY01S RS08930
gene id: 1123384:THY01S_RS08930
uniprot id: A0A0X1KNK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS06610
gene id: 1123384:THY01S_RS06610
uniprot id: A0A0X1KPP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1123384:THY01S RS03720
gene id: 1123384:THY01S_RS03720
uniprot id: A0A0X1KSD8
names: Similarity
messages: Belongs to the UPF0102 family.

1123384:THY01S RS08250
gene id: 1123384:THY01S_RS08250
uniprot id: A0A0X1KNZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1123384:THY01S RS03210
gene id: 1123384:THY01S_RS03210
uniprot id: A0A0X1KS69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS09525
gene id: 1123384:THY01S_RS09525
uniprot id: A0A0X1KT84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS05235
gene id: 1123384:THY01S_RS05235
uniprot id: A0A0X1KQ73
names: Similarity
messages: Belongs to the asp23 family.

1123384:THY01S RS01740
gene id: 1123384:THY01S_RS01740
uniprot id: A0A0X1KRI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1123384:THY01S RS07335
gene id: 1123384:THY01S_RS07335
uniprot id: A0A0X1KP51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1123384:THY01S RS04900
gene id: 1123384:THY01S_RS04900
uniprot id: A0A0X1KSJ4
names: Similarity
messages: Belongs to the hyi family.

1123384:THY01S RS08515
gene id: 1123384:THY01S_RS08515
uniprot id: A0A0X1KNT3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1123384:THY01S RS07745
gene id: 1123384:THY01S_RS07745
uniprot id: A0A0X1KQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS07445
gene id: 1123384:THY01S_RS07445
uniprot id: A0A0X1KP52
names: Similarity
messages: Belongs to the RemA family.

1123384:THY01S RS00275
gene id: 1123384:THY01S_RS00275
uniprot id: A0A0X1KQV3
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10025
gene id: 1123384:THY01S_RS10025
uniprot id: A0A0X1KSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS05555
gene id: 1123384:THY01S_RS05555
uniprot id: A0A0X1KQ14
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS05890
gene id: 1123384:THY01S_RS05890
uniprot id: A0A0X1KQ40
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1123384:THY01S RS02630
gene id: 1123384:THY01S_RS02630
uniprot id: A0A0X1KRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1123384:THY01S RS07485
gene id: 1123384:THY01S_RS07485
uniprot id: A0A0X1KPA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS02830
gene id: 1123384:THY01S_RS02830
uniprot id: A0A0X1KS01
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02260
gene id: 1123384:THY01S_RS02260
uniprot id: A0A0X1KRI5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1123384:THY01S RS03715
gene id: 1123384:THY01S_RS03715
uniprot id: A0A0X1KSA3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1123384:THY01S RS07040
gene id: 1123384:THY01S_RS07040
uniprot id: A0A0X1KPB9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1123384:THY01S RS07675
gene id: 1123384:THY01S_RS07675
uniprot id: A0A0X1KNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1123384:THY01S RS08975
gene id: 1123384:THY01S_RS08975
uniprot id: A0A0X1KNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1123384:THY01S RS04630
gene id: 1123384:THY01S_RS04630
uniprot id: A0A0X1KSN2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123384:THY01S RS04025
gene id: 1123384:THY01S_RS04025
uniprot id: A0A0X1KSN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS10635
gene id: 1123384:THY01S_RS10635
uniprot id: A0A0X1KQJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1123384:THY01S RS04190
gene id: 1123384:THY01S_RS04190
uniprot id: A0A0X1KSR5
names: Similarity
messages: Belongs to the FGGY kinase family.

1123384:THY01S RS03920
gene id: 1123384:THY01S_RS03920
uniprot id: A0A0X1KSY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1123384:THY01S RS01265
gene id: 1123384:THY01S_RS01265
uniprot id: A0A0X1KR47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1123384:THY01S RS02655
gene id: 1123384:THY01S_RS02655
uniprot id: A0A0X1KRJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1123384:THY01S RS10395
gene id: 1123384:THY01S_RS10395
uniprot id: A0A0X1KT39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS10490
gene id: 1123384:THY01S_RS10490
uniprot id: A0A0X1KSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS00395
gene id: 1123384:THY01S_RS00395
uniprot id: A0A0X1KQX2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1123384:THY01S RS08750
gene id: 1123384:THY01S_RS08750
uniprot id: A0A0X1KNM4
names: Similarity
messages: Belongs to the peptidase U62 family.

1123384:THY01S RS05670
gene id: 1123384:THY01S_RS05670
uniprot id: A0A0X1KQ42
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06150
gene id: 1123384:THY01S_RS06150
uniprot id: A0A0X1KPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1123384:THY01S RS06275
gene id: 1123384:THY01S_RS06275
uniprot id: A0A0X1KPT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1123384:THY01S RS07395
gene id: 1123384:THY01S_RS07395
uniprot id: A0A0X1KP70
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1123384:THY01S RS03145
gene id: 1123384:THY01S_RS03145
uniprot id: A0A0X1KRT3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1123384:THY01S RS06525
gene id: 1123384:THY01S_RS06525
uniprot id: A0A0X1KPI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS07765
gene id: 1123384:THY01S_RS07765
uniprot id: A0A0X1KU02
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02455
gene id: 1123384:THY01S_RS02455
uniprot id: A0A0X1KRH8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1123384:THY01S RS01100
gene id: 1123384:THY01S_RS01100
uniprot id: A0A0X1KR14
names: Similarity
messages: Belongs to the UxaA family.

1123384:THY01S RS01235
gene id: 1123384:THY01S_RS01235
uniprot id: A0A0X1KRA3
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS07050
gene id: 1123384:THY01S_RS07050
uniprot id: A0A0X1KPJ7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1123384:THY01S RS01580
gene id: 1123384:THY01S_RS01580
uniprot id: A0A0X1KR94
names: Similarity
messages: Belongs to the UPF0047 family.

1123384:THY01S RS03695
gene id: 1123384:THY01S_RS03695
uniprot id: A0A0X1KS15
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1123384:THY01S RS03610
gene id: 1123384:THY01S_RS03610
uniprot id: A0A0X1KS96
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1123384:THY01S RS01965
gene id: 1123384:THY01S_RS01965
uniprot id: A0A0X1KR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1123384:THY01S RS02755
gene id: 1123384:THY01S_RS02755
uniprot id: A0A0X1KS03
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1123384:THY01S RS04710
gene id: 1123384:THY01S_RS04710
uniprot id: A0A0X1KSD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1123384:THY01S RS04030
gene id: 1123384:THY01S_RS04030
uniprot id: A0A0X1KSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS03620
gene id: 1123384:THY01S_RS03620
uniprot id: A0A0X1KS64
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1123384:THY01S RS05175
gene id: 1123384:THY01S_RS05175
uniprot id: A0A0X1KQ70
names: Similarity
messages: Belongs to the CTP synthase family.

1123384:THY01S RS10075
gene id: 1123384:THY01S_RS10075
uniprot id: A0A0X1KSY8
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS05420
gene id: 1123384:THY01S_RS05420
uniprot id: A0A0X1KQ79
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1123384:THY01S RS06675
gene id: 1123384:THY01S_RS06675
uniprot id: A0A0X1KPG0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1123384:THY01S RS06930
gene id: 1123384:THY01S_RS06930
uniprot id: A0A0X1KPB5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1123384:THY01S RS09535
gene id: 1123384:THY01S_RS09535
uniprot id: A0A0X1KUH6
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS01015
gene id: 1123384:THY01S_RS01015
uniprot id: A0A0X1KQU9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1123384:THY01S RS01085
gene id: 1123384:THY01S_RS01085
uniprot id: A0A0X1KR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS09680
gene id: 1123384:THY01S_RS09680
uniprot id: A0A0X1KUK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1123384:THY01S RS04045
gene id: 1123384:THY01S_RS04045
uniprot id: A0A0X1KSH9
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS05005
gene id: 1123384:THY01S_RS05005
uniprot id: A0A0X1KSF6
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS08730
gene id: 1123384:THY01S_RS08730
uniprot id: A0A0X1KNS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1123384:THY01S RS02700
gene id: 1123384:THY01S_RS02700
uniprot id: A0A0X1KRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1123384:THY01S RS10225
gene id: 1123384:THY01S_RS10225
uniprot id: A0A0X1KT99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1123384:THY01S RS06400
gene id: 1123384:THY01S_RS06400
uniprot id: A0A0X1KPQ8
names: Subcellular Location Annotation
messages: Cytoplasm

1123384:THY01S RS09750
gene id: 1123384:THY01S_RS09750
uniprot id: A0A0X1KT43
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1123384:THY01S RS05615
gene id: 1123384:THY01S_RS05615
uniprot id: A0A0X1KTP1
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1123384:THY01S RS09740
gene id: 1123384:THY01S_RS09740
uniprot id: A0A0X1KTH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1123384:THY01S RS09045
gene id: 1123384:THY01S_RS09045
uniprot id: A0A0X1KNQ6
names: Similarity
messages: Belongs to the RNase H family.

1123384:THY01S RS05310
gene id: 1123384:THY01S_RS05310
uniprot id: A0A0X1KQA1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1123384:THY01S RS00870
gene id: 1123384:THY01S_RS00870
uniprot id: A0A0X1KR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00500
gene id: 1123384:THY01S_RS00500
uniprot id: A0A0X1KQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS06075
gene id: 1123384:THY01S_RS06075
uniprot id: A0A0X1KPQ7
names: Similarity
messages: Belongs to the archease family.

1123384:THY01S RS08185
gene id: 1123384:THY01S_RS08185
uniprot id: A0A0X1KNY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1123384:THY01S RS05040
gene id: 1123384:THY01S_RS05040
uniprot id: A0A0X1KS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS09595
gene id: 1123384:THY01S_RS09595
uniprot id: A0A0X1KT67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1123384:THY01S RS04625
gene id: 1123384:THY01S_RS04625
uniprot id: A0A0X1KSG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1123384:THY01S RS04605
gene id: 1123384:THY01S_RS04605
uniprot id: A0A0X1KSD0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1123384:THY01S RS08795
gene id: 1123384:THY01S_RS08795
uniprot id: A0A0X1KNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1123384:THY01S RS05745
gene id: 1123384:THY01S_RS05745
uniprot id: A0A0X1KPW6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1123384:THY01S RS03865
gene id: 1123384:THY01S_RS03865
uniprot id: A0A0X1KSZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS02985
gene id: 1123384:THY01S_RS02985
uniprot id: A0A0X1KS32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1123384:THY01S RS07305
gene id: 1123384:THY01S_RS07305
uniprot id: A0A0X1KPC0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1123384:THY01S RS02225
gene id: 1123384:THY01S_RS02225
uniprot id: A0A0X1KRC9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1123384:THY01S RS04890
gene id: 1123384:THY01S_RS04890
uniprot id: A0A0X1KSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00655
gene id: 1123384:THY01S_RS00655
uniprot id: A0A0X1KQP4
names: Similarity
messages: Belongs to the peptidase S1C family.

1123384:THY01S RS03240
gene id: 1123384:THY01S_RS03240
uniprot id: A0A0X1KS83
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS06605
gene id: 1123384:THY01S_RS06605
uniprot id: A0A0X1KPM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS08895
gene id: 1123384:THY01S_RS08895
uniprot id: A0A0X1KNS3
names: Similarity
messages: Belongs to the peptidase S41A family.

1123384:THY01S RS05505
gene id: 1123384:THY01S_RS05505
uniprot id: A0A0X1KQ26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

1123384:THY01S RS03140
gene id: 1123384:THY01S_RS03140
uniprot id: A0A0X1KRU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1123384:THY01S RS01765
gene id: 1123384:THY01S_RS01765
uniprot id: A0A0X1KRA6
names: Similarity
messages: Belongs to the peptidase M18 family.

1123384:THY01S RS07170
gene id: 1123384:THY01S_RS07170
uniprot id: A0A0X1KPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1123384:THY01S RS08820
gene id: 1123384:THY01S_RS08820
uniprot id: A0A0X1KNN5
names: Similarity
messages: Belongs to the MEMO1 family.

1123384:THY01S RS02265
gene id: 1123384:THY01S_RS02265
uniprot id: A0A0X1KRK0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1123384:THY01S RS06945
gene id: 1123384:THY01S_RS06945
uniprot id: A0A0X1KPG4
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS05495
gene id: 1123384:THY01S_RS05495
uniprot id: A0A0X1KPZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1123384:THY01S RS04345
gene id: 1123384:THY01S_RS04345
uniprot id: A0A0X1KSL0
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS02740
gene id: 1123384:THY01S_RS02740
uniprot id: A0A0X1KRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1123384:THY01S RS00300
gene id: 1123384:THY01S_RS00300
uniprot id: A0A0X1KQQ8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1123384:THY01S RS02580
gene id: 1123384:THY01S_RS02580
uniprot id: A0A0X1KRM8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1123384:THY01S RS07505
gene id: 1123384:THY01S_RS07505
uniprot id: A0A0X1KP40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1123384:THY01S RS00005
gene id: 1123384:THY01S_RS00005
uniprot id: A0A0X1KQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1123384:THY01S RS10065
gene id: 1123384:THY01S_RS10065
uniprot id: A0A0X1KSZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1123384:THY01S RS03965
gene id: 1123384:THY01S_RS03965
uniprot id: A0A0X1KT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS06085
gene id: 1123384:THY01S_RS06085
uniprot id: A0A0X1KPW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS04760
gene id: 1123384:THY01S_RS04760
uniprot id: A0A0X1KS99
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1123384:THY01S RS09095
gene id: 1123384:THY01S_RS09095
uniprot id: A0A0X1KNP1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1123384:THY01S RS08935
gene id: 1123384:THY01S_RS08935
uniprot id: A0A0X1KNT0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1123384:THY01S RS04490
gene id: 1123384:THY01S_RS04490
uniprot id: A0A0X1KSF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS10475
gene id: 1123384:THY01S_RS10475
uniprot id: A0A0X1KSR6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1123384:THY01S RS06820
gene id: 1123384:THY01S_RS06820
uniprot id: A0A0X1KPI4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1123384:THY01S RS04660
gene id: 1123384:THY01S_RS04660
uniprot id: A0A0X1KSC2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1123384:THY01S RS04980
gene id: 1123384:THY01S_RS04980
uniprot id: A0A0X1KS61
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1123384:THY01S RS04120
gene id: 1123384:THY01S_RS04120
uniprot id: A0A0X1KSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS00455
gene id: 1123384:THY01S_RS00455
uniprot id: A0A0X1KQY6
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1123384:THY01S RS01520
gene id: 1123384:THY01S_RS01520
uniprot id: A0A0X1KR70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1123384:THY01S RS08165
gene id: 1123384:THY01S_RS08165
uniprot id: A0A0X1KP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1123384:THY01S RS05400
gene id: 1123384:THY01S_RS05400
uniprot id: A0A0X1KQ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1123384:THY01S RS06970
gene id: 1123384:THY01S_RS06970
uniprot id: A0A0X1KPB3
names: Similarity
messages: Belongs to the GSP E family.

1123384:THY01S RS06180
gene id: 1123384:THY01S_RS06180
uniprot id: A0A0X1KPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1123384:THY01S RS08115
gene id: 1123384:THY01S_RS08115
uniprot id: A0A0X1KP57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1123384:THY01S RS08650
gene id: 1123384:THY01S_RS08650
uniprot id: A0A0X1KNP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1123384:THY01S RS07215
gene id: 1123384:THY01S_RS07215
uniprot id: A0A0X1KPG6
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS10010
gene id: 1123384:THY01S_RS10010
uniprot id: A0A0X1KT02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1123384:THY01S RS02030
gene id: 1123384:THY01S_RS02030
uniprot id: A0A0X1KRN8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1123384:THY01S RS02810
gene id: 1123384:THY01S_RS02810
uniprot id: A0A0X1KRN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1123384:THY01S RS08100
gene id: 1123384:THY01S_RS08100
uniprot id: A0A0X1KP27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1123384:THY01S RS06940
gene id: 1123384:THY01S_RS06940
uniprot id: A0A0X1KPH5
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS04150
gene id: 1123384:THY01S_RS04150
uniprot id: A0A0X1KSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS01060
gene id: 1123384:THY01S_RS01060
uniprot id: A0A0X1KR82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1123384:THY01S RS03015
gene id: 1123384:THY01S_RS03015
uniprot id: A0A0X1KRQ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1123384:THY01S RS06735
gene id: 1123384:THY01S_RS06735
uniprot id: A0A0X1KPG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1123384:THY01S RS10185
gene id: 1123384:THY01S_RS10185
uniprot id: A0A0X1KSZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1123384:THY01S RS08160
gene id: 1123384:THY01S_RS08160
uniprot id: A0A0X1KP26
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1123384:THY01S RS07795
gene id: 1123384:THY01S_RS07795
uniprot id: A0A0X1KQE2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1123384:THY01S RS08105
gene id: 1123384:THY01S_RS08105
uniprot id: A0A0X1KP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1123384:THY01S RS02560
gene id: 1123384:THY01S_RS02560
uniprot id: A0A0X1KRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1123384:THY01S RS07405
gene id: 1123384:THY01S_RS07405
uniprot id: A0A0X1KP42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1123384:THY01S RS09790
gene id: 1123384:THY01S_RS09790
uniprot id: A0A0X1KT78
names: Subcellular Location Annotation
messages: Membrane

1123384:THY01S RS01475
gene id: 1123384:THY01S_RS01475
uniprot id: A0A0X1KRF7
names: Similarity
messages: Belongs to the AHA1 family.

1123384:THY01S RS08355
gene id: 1123384:THY01S_RS08355
uniprot id: A0A0X1KP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1123384:THY01S RS04690
gene id: 1123384:THY01S_RS04690
uniprot id: A0A0X1KUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane