112234:EG359 RS03725
gene id: 112234:EG359_RS03725
uniprot id: A0A1N7HX70
names: Similarity
messages: Belongs to the glutathione peroxidase family.

112234:EG359 RS00270
gene id: 112234:EG359_RS00270
uniprot id: A0A1N7IEW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09120
gene id: 112234:EG359_RS09120
uniprot id: A0A1N7I3L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS11760
gene id: 112234:EG359_RS11760
uniprot id: A0A1N7IH94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

112234:EG359 RS16775
gene id: 112234:EG359_RS16775
uniprot id: A0A1N7IAV4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

112234:EG359 RS12380
gene id: 112234:EG359_RS12380
uniprot id: A0A1N7II02
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

112234:EG359 RS19835
gene id: 112234:EG359_RS19835
uniprot id: A0A1N7J6J9
names: Similarity
messages: Belongs to the peptidase M16 family.

112234:EG359 RS04755
gene id: 112234:EG359_RS04755
uniprot id: A0A3G6RAQ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

112234:EG359 RS07685
gene id: 112234:EG359_RS07685
uniprot id: A0A1N7JEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS00765
gene id: 112234:EG359_RS00765
uniprot id: A0A1N7IT31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS07180
gene id: 112234:EG359_RS07180
uniprot id: A0A1N7I116
names: Similarity
messages: Belongs to the GbsR family.

112234:EG359 RS01325
gene id: 112234:EG359_RS01325
uniprot id: A0A1N7IQU7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

112234:EG359 RS17630
gene id: 112234:EG359_RS17630
uniprot id: A0A3G6R8H6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

112234:EG359 RS01265
gene id: 112234:EG359_RS01265
uniprot id: A0A1N7IR08
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS01155
gene id: 112234:EG359_RS01155
uniprot id: A0A1N7IRE4
names: Subcellular Location Annotation
messages: Cytoplasm

112234:EG359 RS12395
gene id: 112234:EG359_RS12395
uniprot id: A0A1N7II17
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS17115
gene id: 112234:EG359_RS17115
uniprot id: A0A1N7IAZ7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

112234:EG359 RS01615
gene id: 112234:EG359_RS01615
uniprot id: A0A1N7IPU3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

112234:EG359 RS14105
gene id: 112234:EG359_RS14105
uniprot id: A0A1N7I6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

112234:EG359 RS09575
gene id: 112234:EG359_RS09575
uniprot id: A0A1N7I456
names: Similarity
messages: Belongs to the sigma-54 factor family.

112234:EG359 RS10505
gene id: 112234:EG359_RS10505
uniprot id: A0A1N7IG41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

112234:EG359 RS17510
gene id: 112234:EG359_RS17510
uniprot id: A0A1N7K8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

112234:EG359 RS13195
gene id: 112234:EG359_RS13195
uniprot id: A0A1N7JQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS12505
gene id: 112234:EG359_RS12505
uniprot id: A0A1N7II34
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

112234:EG359 RS21255
gene id: 112234:EG359_RS21255
uniprot id: A0A1N7ID69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS09400
gene id: 112234:EG359_RS09400
uniprot id: A0A1N7I3U9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

112234:EG359 RS01385
gene id: 112234:EG359_RS01385
uniprot id: A0A1N7IQT3
names: Similarity
messages: Belongs to the peptidase M16 family.

112234:EG359 RS07070
gene id: 112234:EG359_RS07070
uniprot id: A0A1N7JBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS10685
gene id: 112234:EG359_RS10685
uniprot id: A0A1N7IGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

112234:EG359 RS21650
gene id: 112234:EG359_RS21650
uniprot id: A0A1N7IDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

112234:EG359 RS01915
gene id: 112234:EG359_RS01915
uniprot id: A0A1N7INR7
names: Similarity
messages: Belongs to the MoaD family.

112234:EG359 RS18325
gene id: 112234:EG359_RS18325
uniprot id: A0A1N7IZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS15255
gene id: 112234:EG359_RS15255
uniprot id: A0A1N7I8K4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

112234:EG359 RS16955
gene id: 112234:EG359_RS16955
uniprot id: A0A3G6RGL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

112234:EG359 RS05590
gene id: 112234:EG359_RS05590
uniprot id: A0A1N7HTY1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

112234:EG359 RS00200
gene id: 112234:EG359_RS00200
uniprot id: A0A1N7IEV7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

112234:EG359 RS01450
gene id: 112234:EG359_RS01450
uniprot id: A0A1N7IQE9
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS18745
gene id: 112234:EG359_RS18745
uniprot id: A0A1N7J1D6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

112234:EG359 RS06475
gene id: 112234:EG359_RS06475
uniprot id: A0A1N7HSJ6
names: Similarity
messages: Belongs to the universal stress protein A family.

112234:EG359 RS09405
gene id: 112234:EG359_RS09405
uniprot id: A0A1N7I3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

112234:EG359 RS07720
gene id: 112234:EG359_RS07720
uniprot id: A0A1N7JF38
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

112234:EG359 RS00490
gene id: 112234:EG359_RS00490
uniprot id: A0A1N7IF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS18035
gene id: 112234:EG359_RS18035
uniprot id: A0A1N7IY14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

112234:EG359 RS15355
gene id: 112234:EG359_RS15355
uniprot id: A0A1N7I8R7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

112234:EG359 RS18195
gene id: 112234:EG359_RS18195
uniprot id: A0A3G6RKG7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

112234:EG359 RS10390
gene id: 112234:EG359_RS10390
uniprot id: A0A1N7IGD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS12560
gene id: 112234:EG359_RS12560
uniprot id: A0A1N7II97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

112234:EG359 RS12225
gene id: 112234:EG359_RS12225
uniprot id: A0A1N7IHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

112234:EG359 RS18845
gene id: 112234:EG359_RS18845
uniprot id: A0A1N7J1P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

112234:EG359 RS16695
gene id: 112234:EG359_RS16695
uniprot id: A0A1N7IAJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS01740
gene id: 112234:EG359_RS01740
uniprot id: A0A1N7IPB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

112234:EG359 RS00335
gene id: 112234:EG359_RS00335
uniprot id: A0A1N7IF16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

112234:EG359 RS18905
gene id: 112234:EG359_RS18905
uniprot id: A0A1N7J283
names: Similarity
messages: Belongs to the glutamate synthase family.

112234:EG359 RS10980
gene id: 112234:EG359_RS10980
uniprot id: A0A1N7IGS6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

112234:EG359 RS10825
gene id: 112234:EG359_RS10825
uniprot id: A0A1N7IGL5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

112234:EG359 RS17530
gene id: 112234:EG359_RS17530
uniprot id: A0A1N7K8E7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16805
gene id: 112234:EG359_RS16805
uniprot id: A0A1N7IAW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

112234:EG359 RS21800
gene id: 112234:EG359_RS21800
uniprot id: A0A3G6RFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

112234:EG359 RS03370
gene id: 112234:EG359_RS03370
uniprot id: A0A1N7HXG9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

112234:EG359 RS03905
gene id: 112234:EG359_RS03905
uniprot id: A0A1N7HX36
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS12000
gene id: 112234:EG359_RS12000
uniprot id: A0A1N7IHI6
names: Similarity
messages: Belongs to the pyruvate kinase family.

112234:EG359 RS04880
gene id: 112234:EG359_RS04880
uniprot id: A0A1N7HVA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

112234:EG359 RS04770
gene id: 112234:EG359_RS04770
uniprot id: A0A3G6RJJ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

112234:EG359 RS14185
gene id: 112234:EG359_RS14185
uniprot id: A0A1N7I6Z0
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS02505
gene id: 112234:EG359_RS02505
uniprot id: A0A1N7IL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

112234:EG359 RS18145
gene id: 112234:EG359_RS18145
uniprot id: A0A1N7IYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

112234:EG359 RS06525
gene id: 112234:EG359_RS06525
uniprot id: A0A1N7HSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

112234:EG359 RS10700
gene id: 112234:EG359_RS10700
uniprot id: A0A1N7IGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

112234:EG359 RS18250
gene id: 112234:EG359_RS18250
uniprot id: A0A1N7IYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

112234:EG359 RS20845
gene id: 112234:EG359_RS20845
uniprot id: A0A1N7ICK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

112234:EG359 RS04515
gene id: 112234:EG359_RS04515
uniprot id: A0A1N7HW37
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

112234:EG359 RS11685
gene id: 112234:EG359_RS11685
uniprot id: A0A1N7IHE6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

112234:EG359 RS02560
gene id: 112234:EG359_RS02560
uniprot id: A0A1N7IL09
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

112234:EG359 RS05455
gene id: 112234:EG359_RS05455
uniprot id: A0A1N7HU66
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

112234:EG359 RS07330
gene id: 112234:EG359_RS07330
uniprot id: A0A1N7I1C9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

112234:EG359 RS16665
gene id: 112234:EG359_RS16665
uniprot id: A0A1N7IAI9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04000
gene id: 112234:EG359_RS04000
uniprot id: A0A1N7HWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

112234:EG359 RS01990
gene id: 112234:EG359_RS01990
uniprot id: A0A1N7INL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS02045
gene id: 112234:EG359_RS02045
uniprot id: A0A1N7IN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

112234:EG359 RS04495
gene id: 112234:EG359_RS04495
uniprot id: A0A3G6RAX0
names: Similarity
messages: Belongs to the peptidase S51 family.

112234:EG359 RS14345
gene id: 112234:EG359_RS14345
uniprot id: A0A1N7I775
names: Similarity
messages: Belongs to the phosphohexose mutase family.

112234:EG359 RS04445
gene id: 112234:EG359_RS04445
uniprot id: A0A1N7HW34
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

112234:EG359 RS01185
gene id: 112234:EG359_RS01185
uniprot id: A0A1N7IR94
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09525
gene id: 112234:EG359_RS09525
uniprot id: A0A1N7I420
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

112234:EG359 RS21280
gene id: 112234:EG359_RS21280
uniprot id: A0A1N7ID79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

112234:EG359 RS01755
gene id: 112234:EG359_RS01755
uniprot id: A0A1N7IPH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS16890
gene id: 112234:EG359_RS16890
uniprot id: A0A1N7IAR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04170
gene id: 112234:EG359_RS04170
uniprot id: A0A1N7HWU3
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS12245
gene id: 112234:EG359_RS12245
uniprot id: A0A1N7IHN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS21600
gene id: 112234:EG359_RS21600
uniprot id: A0A1N7IDQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

112234:EG359 RS19525
gene id: 112234:EG359_RS19525
uniprot id: A0A1N7J4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

112234:EG359 RS11765
gene id: 112234:EG359_RS11765
uniprot id: A0A1N7IHB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

112234:EG359 RS12665
gene id: 112234:EG359_RS12665
uniprot id: A0A1N7IIE2
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS11375
gene id: 112234:EG359_RS11375
uniprot id: A0A1N7IH34
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

112234:EG359 RS04615
gene id: 112234:EG359_RS04615
uniprot id: A0A1N7HVV7
names: Similarity
messages: Belongs to the UPF0246 family.

112234:EG359 RS21940
gene id: 112234:EG359_RS21940
uniprot id: A0A1N7IE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

112234:EG359 RS04190
gene id: 112234:EG359_RS04190
uniprot id: A0A1N7HWH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

112234:EG359 RS03220
gene id: 112234:EG359_RS03220
uniprot id: A0A1N7HXQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

112234:EG359 RS09620
gene id: 112234:EG359_RS09620
uniprot id: A0A1N7I460
names: Similarity
messages: Belongs to the nitroreductase family.

112234:EG359 RS00425
gene id: 112234:EG359_RS00425
uniprot id: A0A1N7IF71
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS02120
gene id: 112234:EG359_RS02120
uniprot id: A0A1N7IMV4
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS18315
gene id: 112234:EG359_RS18315
uniprot id: A0A1N7IZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

112234:EG359 RS03635
gene id: 112234:EG359_RS03635
uniprot id: A0A1N7HXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

112234:EG359 RS03175
gene id: 112234:EG359_RS03175
uniprot id: A0A1N7HXU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS13285
gene id: 112234:EG359_RS13285
uniprot id: A0A1N7JRT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

112234:EG359 RS21465
gene id: 112234:EG359_RS21465
uniprot id: A0A1N7IDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

112234:EG359 RS16005
gene id: 112234:EG359_RS16005
uniprot id: A0A1N7I9I4
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16235
gene id: 112234:EG359_RS16235
uniprot id: A0A1N7I9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

112234:EG359 RS13515
gene id: 112234:EG359_RS13515
uniprot id: A0A1N7JUP0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

112234:EG359 RS07845
gene id: 112234:EG359_RS07845
uniprot id: A0A1N7I224
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS15870
gene id: 112234:EG359_RS15870
uniprot id: A0A1N7I9H8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS17660
gene id: 112234:EG359_RS17660
uniprot id: A0A1N7K6T3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

112234:EG359 RS05820
gene id: 112234:EG359_RS05820
uniprot id: A0A1N7HTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS07985
gene id: 112234:EG359_RS07985
uniprot id: A0A1N7I259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS09465
gene id: 112234:EG359_RS09465
uniprot id: A0A1N7I3Y5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

112234:EG359 RS18160
gene id: 112234:EG359_RS18160
uniprot id: A0A1N7IYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

112234:EG359 RS01260
gene id: 112234:EG359_RS01260
uniprot id: A0A1N7IR13
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14380
gene id: 112234:EG359_RS14380
uniprot id: A0A1N7I7C1
names: Similarity
messages: Belongs to the DinB family.

112234:EG359 RS21415
gene id: 112234:EG359_RS21415
uniprot id: A0A1N7IDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

112234:EG359 RS22060
gene id: 112234:EG359_RS22060
uniprot id: A0A1N7IEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

112234:EG359 RS16085
gene id: 112234:EG359_RS16085
uniprot id: A0A1N7I9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

112234:EG359 RS09475
gene id: 112234:EG359_RS09475
uniprot id: A0A1N7I412
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

112234:EG359 RS20955
gene id: 112234:EG359_RS20955
uniprot id: A0A1N7ICP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS11830
gene id: 112234:EG359_RS11830
uniprot id: A0A1N7IHC1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

112234:EG359 RS03275
gene id: 112234:EG359_RS03275
uniprot id: A0A1N7HXN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS04325
gene id: 112234:EG359_RS04325
uniprot id: A0A1N7HWA7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

112234:EG359 RS21825
gene id: 112234:EG359_RS21825
uniprot id: A0A1N7IE65
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

112234:EG359 RS12775
gene id: 112234:EG359_RS12775
uniprot id: A0A1N7JKV0
names: Similarity
messages: Belongs to the Skp family.

112234:EG359 RS09945
gene id: 112234:EG359_RS09945
uniprot id: A0A3G6RB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

112234:EG359 RS21085
gene id: 112234:EG359_RS21085
uniprot id: A0A1N7ICW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

112234:EG359 RS14630
gene id: 112234:EG359_RS14630
uniprot id: A0A1N7I7N7
names: Similarity
messages: Belongs to the peptidase S41A family.

112234:EG359 RS08430
gene id: 112234:EG359_RS08430
uniprot id: A0A1N7I2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS15545
gene id: 112234:EG359_RS15545
uniprot id: A0A1N7I952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS12455
gene id: 112234:EG359_RS12455
uniprot id: A0A1N7II05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

112234:EG359 RS11805
gene id: 112234:EG359_RS11805
uniprot id: A0A1N7IHA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

112234:EG359 RS00140
gene id: 112234:EG359_RS00140
uniprot id: A0A1N7IF43
names: Similarity
messages: Belongs to the GARS family.

112234:EG359 RS00040
gene id: 112234:EG359_RS00040
uniprot id: A0A1N7IEX2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS00345
gene id: 112234:EG359_RS00345
uniprot id: A0A1N7IF31
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS21190
gene id: 112234:EG359_RS21190
uniprot id: A0A1N7ID43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS11505
gene id: 112234:EG359_RS11505
uniprot id: A0A1N7IH40
names: Similarity
messages: Belongs to the Nudix hydrolase family.

112234:EG359 RS22120
gene id: 112234:EG359_RS22120
uniprot id: A0A1N7IEM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

112234:EG359 RS13095
gene id: 112234:EG359_RS13095
uniprot id: A0A1N7JP35
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

112234:EG359 RS10425
gene id: 112234:EG359_RS10425
uniprot id: A0A1N7IG12
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS20105
gene id: 112234:EG359_RS20105
uniprot id: A0A1N7KCY4
names: Similarity
messages: Belongs to the DEAD box helicase family.

112234:EG359 RS07255
gene id: 112234:EG359_RS07255
uniprot id: A0A1N7JCH8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

112234:EG359 RS13250
gene id: 112234:EG359_RS13250
uniprot id: A0A1N7JR20
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04450
gene id: 112234:EG359_RS04450
uniprot id: A0A1N7HW54
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

112234:EG359 RS15555
gene id: 112234:EG359_RS15555
uniprot id: A0A1N7I940
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

112234:EG359 RS13885
gene id: 112234:EG359_RS13885
uniprot id: A0A1N7JZ72
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

112234:EG359 RS17810
gene id: 112234:EG359_RS17810
uniprot id: A0A1N7K541
names: Similarity
messages: Belongs to the ClpX chaperone family.

112234:EG359 RS13180
gene id: 112234:EG359_RS13180
uniprot id: A0A1N7JQF6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

112234:EG359 RS03125
gene id: 112234:EG359_RS03125
uniprot id: A0A1N7HXX0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

112234:EG359 RS12135
gene id: 112234:EG359_RS12135
uniprot id: A0A1N7IHR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS07375
gene id: 112234:EG359_RS07375
uniprot id: A0A1N7JD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS11985
gene id: 112234:EG359_RS11985
uniprot id: A0A1N7IHJ8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

112234:EG359 RS19365
gene id: 112234:EG359_RS19365
uniprot id: A0A1N7J4F5
names: Similarity
messages: Belongs to the LOG family.

112234:EG359 RS12175
gene id: 112234:EG359_RS12175
uniprot id: A0A1N7IHP5
names: Similarity
messages: Belongs to the NusB family.

112234:EG359 RS16935
gene id: 112234:EG359_RS16935
uniprot id: A0A1N7IAS9
names: Similarity
messages: Belongs to the RecJ family.

112234:EG359 RS12765
gene id: 112234:EG359_RS12765
uniprot id: A0A1N7JL01
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

112234:EG359 RS01345
gene id: 112234:EG359_RS01345
uniprot id: A0A1N7IQR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS11990
gene id: 112234:EG359_RS11990
uniprot id: A0A1N7IHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

112234:EG359 RS04895
gene id: 112234:EG359_RS04895
uniprot id: A0A1N7HV97
names: Similarity
messages: Belongs to the sterol desaturase family.

112234:EG359 RS12375
gene id: 112234:EG359_RS12375
uniprot id: A0A1N7IHU4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

112234:EG359 RS20080
gene id: 112234:EG359_RS20080
uniprot id: A0A1N7KCS2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

112234:EG359 RS11150
gene id: 112234:EG359_RS11150
uniprot id: A0A1N7IH80
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

112234:EG359 RS18830
gene id: 112234:EG359_RS18830
uniprot id: A0A1N7J1H0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS05200
gene id: 112234:EG359_RS05200
uniprot id: A0A1N7HUJ5
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

112234:EG359 RS16985
gene id: 112234:EG359_RS16985
uniprot id: A0A1N7IAT9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS03055
gene id: 112234:EG359_RS03055
uniprot id: A0A1N7HY13
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS11845
gene id: 112234:EG359_RS11845
uniprot id: A0A1N7IHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

112234:EG359 RS07345
gene id: 112234:EG359_RS07345
uniprot id: A0A1N7JCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

112234:EG359 RS18335
gene id: 112234:EG359_RS18335
uniprot id: A0A1N7IZD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS15455
gene id: 112234:EG359_RS15455
uniprot id: A0A1N7I8Z3
names: Similarity
messages: Belongs to the glutamine synthetase family.

112234:EG359 RS13805
gene id: 112234:EG359_RS13805
uniprot id: A0A1N7JY17
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

112234:EG359 RS13135
gene id: 112234:EG359_RS13135
uniprot id: A0A1N7JPM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

112234:EG359 RS18990
gene id: 112234:EG359_RS18990
uniprot id: A0A1N7J287
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS20175
gene id: 112234:EG359_RS20175
uniprot id: A0A3G6R9S4
names: Similarity
messages: Belongs to the ParB family.

112234:EG359 RS15410
gene id: 112234:EG359_RS15410
uniprot id: A0A1N7I8U3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

112234:EG359 RS21080
gene id: 112234:EG359_RS21080
uniprot id: A0A1N7ICW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

112234:EG359 RS18425
gene id: 112234:EG359_RS18425
uniprot id: A0A1N7IZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

112234:EG359 RS14085
gene id: 112234:EG359_RS14085
uniprot id: A0A1N7I6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

112234:EG359 RS15650
gene id: 112234:EG359_RS15650
uniprot id: A0A1N7I980
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

112234:EG359 RS15895
gene id: 112234:EG359_RS15895
uniprot id: A0A1N7I9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

112234:EG359 RS19470
gene id: 112234:EG359_RS19470
uniprot id: A0A1N7J4I6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

112234:EG359 RS02830
gene id: 112234:EG359_RS02830
uniprot id: A0A1N7HYE3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

112234:EG359 RS21925
gene id: 112234:EG359_RS21925
uniprot id: A0A1N7IE84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

112234:EG359 RS15450
gene id: 112234:EG359_RS15450
uniprot id: A0A1N7I8X0
names: Similarity
messages: Belongs to the peptidase C40 family.

112234:EG359 RS13140
gene id: 112234:EG359_RS13140
uniprot id: A0A3G6R8S2
names: Similarity
messages: Belongs to the catalase family.

112234:EG359 RS21585
gene id: 112234:EG359_RS21585
uniprot id: A0A1N7IDQ1
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15485
gene id: 112234:EG359_RS15485
uniprot id: A0A1N7I917
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

112234:EG359 RS04645
gene id: 112234:EG359_RS04645
uniprot id: A0A1N7HVX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS14865
gene id: 112234:EG359_RS14865
uniprot id: A0A1N7I7Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS07865
gene id: 112234:EG359_RS07865
uniprot id: A0A1N7JFF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

112234:EG359 RS14100
gene id: 112234:EG359_RS14100
uniprot id: A0A1N7I6U6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04845
gene id: 112234:EG359_RS04845
uniprot id: A0A1N7HVA0
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

112234:EG359 RS00420
gene id: 112234:EG359_RS00420
uniprot id: A0A1N7IF45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

112234:EG359 RS20565
gene id: 112234:EG359_RS20565
uniprot id: A0A1N7IC05
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

112234:EG359 RS10645
gene id: 112234:EG359_RS10645
uniprot id: A0A1N7IGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS15995
gene id: 112234:EG359_RS15995
uniprot id: A0A1N7I9T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

112234:EG359 RS21660
gene id: 112234:EG359_RS21660
uniprot id: A0A1N7IDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

112234:EG359 RS15440
gene id: 112234:EG359_RS15440
uniprot id: A0A1N7I8U9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS06725
gene id: 112234:EG359_RS06725
uniprot id: A0A1N7I0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

112234:EG359 RS12235
gene id: 112234:EG359_RS12235
uniprot id: A0A1N7IHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

112234:EG359 RS04120
gene id: 112234:EG359_RS04120
uniprot id: A0A1N7HWL3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS07695
gene id: 112234:EG359_RS07695
uniprot id: A0A1N7I1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

112234:EG359 RS02195
gene id: 112234:EG359_RS02195
uniprot id: A0A1N7IML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

112234:EG359 RS16740
gene id: 112234:EG359_RS16740
uniprot id: A0A1N7IAL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

112234:EG359 RS14910
gene id: 112234:EG359_RS14910
uniprot id: A0A3G6RFR4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

112234:EG359 RS15470
gene id: 112234:EG359_RS15470
uniprot id: A0A1N7I8Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS08305
gene id: 112234:EG359_RS08305
uniprot id: A0A1N7JHC6
names: Similarity
messages: Belongs to the terpene synthase family.

112234:EG359 RS17425
gene id: 112234:EG359_RS17425
uniprot id: A0A1N7K9Y0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

112234:EG359 RS09965
gene id: 112234:EG359_RS09965
uniprot id: A0A1N7I4Q4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

112234:EG359 RS21285
gene id: 112234:EG359_RS21285
uniprot id: A0A1N7IDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

112234:EG359 RS06825
gene id: 112234:EG359_RS06825
uniprot id: A0A1N7I0G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS06355
gene id: 112234:EG359_RS06355
uniprot id: A0A1N7HSI2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

112234:EG359 RS05330
gene id: 112234:EG359_RS05330
uniprot id: A0A1N7HUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

112234:EG359 RS03995
gene id: 112234:EG359_RS03995
uniprot id: A0A1N7HWX5
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04115
gene id: 112234:EG359_RS04115
uniprot id: A0A3G6R1E4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS11030
gene id: 112234:EG359_RS11030
uniprot id: A0A1N7IGU4
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

112234:EG359 RS12370
gene id: 112234:EG359_RS12370
uniprot id: A0A1N7II89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

112234:EG359 RS16770
gene id: 112234:EG359_RS16770
uniprot id: A0A1N7IAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

112234:EG359 RS21345
gene id: 112234:EG359_RS21345
uniprot id: A0A1N7ID96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS16835
gene id: 112234:EG359_RS16835
uniprot id: A0A1N7IAM3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

112234:EG359 RS17935
gene id: 112234:EG359_RS17935
uniprot id: A0A1N7K364
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

112234:EG359 RS19125
gene id: 112234:EG359_RS19125
uniprot id: A0A1N7J357
names: Similarity
messages: Belongs to the asparaginase 1 family.

112234:EG359 RS15400
gene id: 112234:EG359_RS15400
uniprot id: A0A1N7I8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS13120
gene id: 112234:EG359_RS13120
uniprot id: A0A1N7JPR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS08635
gene id: 112234:EG359_RS08635
uniprot id: A0A1N7I315
names: Similarity
messages: Belongs to the NAD synthetase family.

112234:EG359 RS14500
gene id: 112234:EG359_RS14500
uniprot id: A0A1N7I7G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

112234:EG359 RS11650
gene id: 112234:EG359_RS11650
uniprot id: A0A3G6R8J4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS14830
gene id: 112234:EG359_RS14830
uniprot id: A0A1N7I808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

112234:EG359 RS03375
gene id: 112234:EG359_RS03375
uniprot id: A0A1N7HXL0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

112234:EG359 RS11285
gene id: 112234:EG359_RS11285
uniprot id: A0A1N7IGY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

112234:EG359 RS03795
gene id: 112234:EG359_RS03795
uniprot id: A0A1N7HXB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16815
gene id: 112234:EG359_RS16815
uniprot id: A0A1N7IAP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

112234:EG359 RS03180
gene id: 112234:EG359_RS03180
uniprot id: A0A1N7HY41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

112234:EG359 RS01320
gene id: 112234:EG359_RS01320
uniprot id: A0A1N7IQV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

112234:EG359 RS11330
gene id: 112234:EG359_RS11330
uniprot id: A0A1N7IGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

112234:EG359 RS09830
gene id: 112234:EG359_RS09830
uniprot id: A0A1N7I4D6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

112234:EG359 RS10530
gene id: 112234:EG359_RS10530
uniprot id: A0A1N7IG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

112234:EG359 RS00320
gene id: 112234:EG359_RS00320
uniprot id: A0A1N7IF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

112234:EG359 RS16725
gene id: 112234:EG359_RS16725
uniprot id: A0A1N7IAK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS09050
gene id: 112234:EG359_RS09050
uniprot id: A0A1N7I3I6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS21880
gene id: 112234:EG359_RS21880
uniprot id: A0A1N7IE91
names: Similarity
messages: Belongs to the TrpF family.

112234:EG359 RS03390
gene id: 112234:EG359_RS03390
uniprot id: A0A1N7HXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS07205
gene id: 112234:EG359_RS07205
uniprot id: A0A1N7JCD4
names: Similarity
messages: Belongs to the peptidase C1 family.

112234:EG359 RS08455
gene id: 112234:EG359_RS08455
uniprot id: A0A3G6R6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS16285
gene id: 112234:EG359_RS16285
uniprot id: A0A1N7IA05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

112234:EG359 RS20575
gene id: 112234:EG359_RS20575
uniprot id: A0A1N7IC09
names: Similarity
messages: Belongs to the CinA family.

112234:EG359 RS10790
gene id: 112234:EG359_RS10790
uniprot id: A0A1N7IGG5
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01465
gene id: 112234:EG359_RS01465
uniprot id: A0A1N7IQA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

112234:EG359 RS14365
gene id: 112234:EG359_RS14365
uniprot id: A0A1N7I793
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

112234:EG359 RS03185
gene id: 112234:EG359_RS03185
uniprot id: A0A1N7HY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS13995
gene id: 112234:EG359_RS13995
uniprot id: A0A1N7I6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS03070
gene id: 112234:EG359_RS03070
uniprot id: A0A1N7HY03
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15875
gene id: 112234:EG359_RS15875
uniprot id: A0A1N7I9G3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS07395
gene id: 112234:EG359_RS07395
uniprot id: A0A1N7I1H0
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14875
gene id: 112234:EG359_RS14875
uniprot id: A0A1N7I7W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS05530
gene id: 112234:EG359_RS05530
uniprot id: A0A1N7HU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

112234:EG359 RS11855
gene id: 112234:EG359_RS11855
uniprot id: A0A1N7IHA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS05615
gene id: 112234:EG359_RS05615
uniprot id: A0A1N7HTW8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS03310
gene id: 112234:EG359_RS03310
uniprot id: A0A1N7HXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS04425
gene id: 112234:EG359_RS04425
uniprot id: A0A1N7HW00
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

112234:EG359 RS13635
gene id: 112234:EG359_RS13635
uniprot id: A0A1N7JW07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

112234:EG359 RS12625
gene id: 112234:EG359_RS12625
uniprot id: A0A1N7IIH4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS09375
gene id: 112234:EG359_RS09375
uniprot id: A0A1N7I3T8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS06685
gene id: 112234:EG359_RS06685
uniprot id: A0A1N7HS98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

112234:EG359 RS14080
gene id: 112234:EG359_RS14080
uniprot id: A0A1N7I6R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

112234:EG359 RS20500
gene id: 112234:EG359_RS20500
uniprot id: A0A1N7IBY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS15145
gene id: 112234:EG359_RS15145
uniprot id: A0A1N7I8E3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS07155
gene id: 112234:EG359_RS07155
uniprot id: A0A1N7JC13
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

112234:EG359 RS15205
gene id: 112234:EG359_RS15205
uniprot id: A0A1N7I8H5
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16690
gene id: 112234:EG359_RS16690
uniprot id: A0A1N7IAI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

112234:EG359 RS08415
gene id: 112234:EG359_RS08415
uniprot id: A0A1N7I2P9
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS12145
gene id: 112234:EG359_RS12145
uniprot id: A0A1N7IHN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

112234:EG359 RS05585
gene id: 112234:EG359_RS05585
uniprot id: A0A1N7HTY5
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

112234:EG359 RS00105
gene id: 112234:EG359_RS00105
uniprot id: A0A1N7IET5
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09245
gene id: 112234:EG359_RS09245
uniprot id: A0A1N7I3N6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

112234:EG359 RS13820
gene id: 112234:EG359_RS13820
uniprot id: A0A1N7JYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16260
gene id: 112234:EG359_RS16260
uniprot id: A0A1N7IA51
names: Similarity
messages: Belongs to the BshC family.

112234:EG359 RS19930
gene id: 112234:EG359_RS19930
uniprot id: A0A1N7KIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS10900
gene id: 112234:EG359_RS10900
uniprot id: A0A1N7IGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

112234:EG359 RS18815
gene id: 112234:EG359_RS18815
uniprot id: A0A1N7J1I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

112234:EG359 RS21860
gene id: 112234:EG359_RS21860
uniprot id: A0A1N7IE32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

112234:EG359 RS10850
gene id: 112234:EG359_RS10850
uniprot id: A0A1N7IGX8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

112234:EG359 RS14120
gene id: 112234:EG359_RS14120
uniprot id: A0A1N7I6S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS19320
gene id: 112234:EG359_RS19320
uniprot id: A0A1N7J3Z1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS06510
gene id: 112234:EG359_RS06510
uniprot id: A0A1N7HSA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

112234:EG359 RS14220
gene id: 112234:EG359_RS14220
uniprot id: A0A1N7I6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS00115
gene id: 112234:EG359_RS00115
uniprot id: A0A1N7IEP7
names: Similarity
messages: Belongs to the pirin family.

112234:EG359 RS11350
gene id: 112234:EG359_RS11350
uniprot id: A0A1N7IH07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16550
gene id: 112234:EG359_RS16550
uniprot id: A0A1N7IAD3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS02705
gene id: 112234:EG359_RS02705
uniprot id: A0A1N7HYP3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

112234:EG359 RS16480
gene id: 112234:EG359_RS16480
uniprot id: A0A1N7IAE8
names: Similarity
messages: Belongs to the RutC family.

112234:EG359 RS16960
gene id: 112234:EG359_RS16960
uniprot id: A0A1N7IB03
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

112234:EG359 RS17535
gene id: 112234:EG359_RS17535
uniprot id: A0A1N7K8D5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

112234:EG359 RS20125
gene id: 112234:EG359_RS20125
uniprot id: A0A1N7KDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS18880
gene id: 112234:EG359_RS18880
uniprot id: A0A1N7J1P6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

112234:EG359 RS09445
gene id: 112234:EG359_RS09445
uniprot id: A0A1N7I3X6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS10775
gene id: 112234:EG359_RS10775
uniprot id: A0A1N7IGU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

112234:EG359 RS16795
gene id: 112234:EG359_RS16795
uniprot id: A0A1N7IAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

112234:EG359 RS13210
gene id: 112234:EG359_RS13210
uniprot id: A0A1N7JQT0
names: Subcellular Location Annotation
messages: Mitochondrion

112234:EG359 RS17050
gene id: 112234:EG359_RS17050
uniprot id: A0A1N7IAY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

112234:EG359 RS13560
gene id: 112234:EG359_RS13560
uniprot id: A0A1N7JV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16345
gene id: 112234:EG359_RS16345
uniprot id: A0A3G6RE22
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS08440
gene id: 112234:EG359_RS08440
uniprot id: A0A1N7I2S3
names: Similarity
messages: Belongs to the peptidase M1 family.

112234:EG359 RS13150
gene id: 112234:EG359_RS13150
uniprot id: A0A1N7JQ37
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

112234:EG359 RS03430
gene id: 112234:EG359_RS03430
uniprot id: A0A1N7HXH1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

112234:EG359 RS10705
gene id: 112234:EG359_RS10705
uniprot id: A0A1N7IGR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

112234:EG359 RS18190
gene id: 112234:EG359_RS18190
uniprot id: A0A3G6RE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

112234:EG359 RS04015
gene id: 112234:EG359_RS04015
uniprot id: A0A1N7HWX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

112234:EG359 RS20065
gene id: 112234:EG359_RS20065
uniprot id: A0A1N7KCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

112234:EG359 RS03410
gene id: 112234:EG359_RS03410
uniprot id: A0A3G6RE53
names: Similarity
messages: Belongs to the peptidase S33 family.

112234:EG359 RS14485
gene id: 112234:EG359_RS14485
uniprot id: A0A1N7I7J0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS05535
gene id: 112234:EG359_RS05535
uniprot id: A0A1N7HTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS10525
gene id: 112234:EG359_RS10525
uniprot id: A0A1N7IG60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

112234:EG359 RS02810
gene id: 112234:EG359_RS02810
uniprot id: A0A1N7HYI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

112234:EG359 RS09900
gene id: 112234:EG359_RS09900
uniprot id: A0A1N7I4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS20155
gene id: 112234:EG359_RS20155
uniprot id: A0A1N7KDH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

112234:EG359 RS12345
gene id: 112234:EG359_RS12345
uniprot id: A0A1N7IHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

112234:EG359 RS11795
gene id: 112234:EG359_RS11795
uniprot id: A0A1N7IHD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

112234:EG359 RS04030
gene id: 112234:EG359_RS04030
uniprot id: A0A1N7HX04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

112234:EG359 RS15805
gene id: 112234:EG359_RS15805
uniprot id: A0A1N7I9K5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS21945
gene id: 112234:EG359_RS21945
uniprot id: A0A1N7IEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

112234:EG359 RS03455
gene id: 112234:EG359_RS03455
uniprot id: A0A1N7HXG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

112234:EG359 RS18085
gene id: 112234:EG359_RS18085
uniprot id: A0A1N7IYH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

112234:EG359 RS08900
gene id: 112234:EG359_RS08900
uniprot id: A0A1N7I3G1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS12615
gene id: 112234:EG359_RS12615
uniprot id: A0A1N7IIM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS14140
gene id: 112234:EG359_RS14140
uniprot id: A0A1N7I6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

112234:EG359 RS21400
gene id: 112234:EG359_RS21400
uniprot id: A0A1N7IDI9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

112234:EG359 RS16205
gene id: 112234:EG359_RS16205
uniprot id: A0A1N7I9W0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

112234:EG359 RS05490
gene id: 112234:EG359_RS05490
uniprot id: A0A1N7HU48
names: Similarity
messages: Belongs to the ArsC family.

112234:EG359 RS04910
gene id: 112234:EG359_RS04910
uniprot id: A0A1N7HV36
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

112234:EG359 RS01145
gene id: 112234:EG359_RS01145
uniprot id: A0A1N7IRL6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04065
gene id: 112234:EG359_RS04065
uniprot id: A0A1N7HWS9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

112234:EG359 RS08910
gene id: 112234:EG359_RS08910
uniprot id: A0A1N7I3H9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS07275
gene id: 112234:EG359_RS07275
uniprot id: A0A1N7I1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

112234:EG359 RS14320
gene id: 112234:EG359_RS14320
uniprot id: A0A1N7I763
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

112234:EG359 RS21995
gene id: 112234:EG359_RS21995
uniprot id: A0A1N7IEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS11000
gene id: 112234:EG359_RS11000
uniprot id: A0A1N7IGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

112234:EG359 RS02140
gene id: 112234:EG359_RS02140
uniprot id: A0A1N7IMS7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09780
gene id: 112234:EG359_RS09780
uniprot id: A0A1N7I4C4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

112234:EG359 RS08145
gene id: 112234:EG359_RS08145
uniprot id: A0A1N7JGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS06955
gene id: 112234:EG359_RS06955
uniprot id: A0A1N7JAX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09865
gene id: 112234:EG359_RS09865
uniprot id: A0A1N7I4J2
names: Similarity
messages: Belongs to the universal stress protein A family.

112234:EG359 RS04175
gene id: 112234:EG359_RS04175
uniprot id: A0A1N7HWH7
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

112234:EG359 RS03755
gene id: 112234:EG359_RS03755
uniprot id: A0A1N7HX63
names: Similarity
messages: Belongs to the phosphohexose mutase family.

112234:EG359 RS20200
gene id: 112234:EG359_RS20200
uniprot id: A0A3G6RIR6
names: Similarity
messages: Belongs to the peptidase S8 family.

112234:EG359 RS00265
gene id: 112234:EG359_RS00265
uniprot id: A0A1N7IF28
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

112234:EG359 RS14610
gene id: 112234:EG359_RS14610
uniprot id: A0A1N7I7K9
names: Similarity
messages: Belongs to the Lgt family.

112234:EG359 RS15285
gene id: 112234:EG359_RS15285
uniprot id: A0A3G6R780
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

112234:EG359 RS12790
gene id: 112234:EG359_RS12790
uniprot id: A0A1N7JL83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

112234:EG359 RS15920
gene id: 112234:EG359_RS15920
uniprot id: A0A1N7I9J1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

112234:EG359 RS22115
gene id: 112234:EG359_RS22115
uniprot id: A0A1N7IEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

112234:EG359 RS10935
gene id: 112234:EG359_RS10935
uniprot id: A0A3G6RAV9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

112234:EG359 RS09350
gene id: 112234:EG359_RS09350
uniprot id: A0A1N7I3S4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

112234:EG359 RS12905
gene id: 112234:EG359_RS12905
uniprot id: A0A1N7JMB8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS13675
gene id: 112234:EG359_RS13675
uniprot id: A0A1N7JWP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS03940
gene id: 112234:EG359_RS03940
uniprot id: A0A1N7HX86
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

112234:EG359 RS15330
gene id: 112234:EG359_RS15330
uniprot id: A0A1N7I8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

112234:EG359 RS10730
gene id: 112234:EG359_RS10730
uniprot id: A0A1N7IGI0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

112234:EG359 RS20515
gene id: 112234:EG359_RS20515
uniprot id: A0A1N7IBZ6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS19275
gene id: 112234:EG359_RS19275
uniprot id: A0A1N7J3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

112234:EG359 RS15745
gene id: 112234:EG359_RS15745
uniprot id: A0A1N7I9I6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS20830
gene id: 112234:EG359_RS20830
uniprot id: A0A1N7ICJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

112234:EG359 RS12065
gene id: 112234:EG359_RS12065
uniprot id: A0A1N7IHL0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

112234:EG359 RS16290
gene id: 112234:EG359_RS16290
uniprot id: A0A1N7IA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS19255
gene id: 112234:EG359_RS19255
uniprot id: A0A1N7J3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

112234:EG359 RS07740
gene id: 112234:EG359_RS07740
uniprot id: A0A1N7I1Y8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

112234:EG359 RS10865
gene id: 112234:EG359_RS10865
uniprot id: A0A1N7IGQ2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

112234:EG359 RS12500
gene id: 112234:EG359_RS12500
uniprot id: A0A1N7II63
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

112234:EG359 RS16810
gene id: 112234:EG359_RS16810
uniprot id: A0A1N7IAP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

112234:EG359 RS11320
gene id: 112234:EG359_RS11320
uniprot id: A0A1N7IH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS04750
gene id: 112234:EG359_RS04750
uniprot id: A0A1N7HVE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

112234:EG359 RS15965
gene id: 112234:EG359_RS15965
uniprot id: A0A1N7I9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

112234:EG359 RS08520
gene id: 112234:EG359_RS08520
uniprot id: A0A1N7I2W2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS12020
gene id: 112234:EG359_RS12020
uniprot id: A0A1N7IHM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

112234:EG359 RS20705
gene id: 112234:EG359_RS20705
uniprot id: A0A1N7IC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

112234:EG359 RS07305
gene id: 112234:EG359_RS07305
uniprot id: A0A1N7I1I1
names: Similarity
messages: Belongs to the peptidase S9C family.

112234:EG359 RS10025
gene id: 112234:EG359_RS10025
uniprot id: A0A1N7I4R6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

112234:EG359 RS16225
gene id: 112234:EG359_RS16225
uniprot id: A0A1N7I9Y9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

112234:EG359 RS15190
gene id: 112234:EG359_RS15190
uniprot id: A0A1N7I8G7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01290
gene id: 112234:EG359_RS01290
uniprot id: A0A1N7IQY9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS07085
gene id: 112234:EG359_RS07085
uniprot id: A0A3G6R8W3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

112234:EG359 RS21430
gene id: 112234:EG359_RS21430
uniprot id: A0A1N7IDK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

112234:EG359 RS01340
gene id: 112234:EG359_RS01340
uniprot id: A0A1N7IQS5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

112234:EG359 RS13145
gene id: 112234:EG359_RS13145
uniprot id: A0A1N7JPT2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

112234:EG359 RS21730
gene id: 112234:EG359_RS21730
uniprot id: A0A1N7IDX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

112234:EG359 RS19355
gene id: 112234:EG359_RS19355
uniprot id: A0A1N7J487
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS08330
gene id: 112234:EG359_RS08330
uniprot id: A0A1N7I2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS02165
gene id: 112234:EG359_RS02165
uniprot id: A0A1N7IMN8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS13690
gene id: 112234:EG359_RS13690
uniprot id: A0A1N7JWN3
names: Similarity
messages: Belongs to the TPP enzyme family.

112234:EG359 RS20375
gene id: 112234:EG359_RS20375
uniprot id: A0A1N7IBP5
names: Similarity
messages: Belongs to the transposase 27 family.

112234:EG359 RS00125
gene id: 112234:EG359_RS00125
uniprot id: A0A1N7IEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

112234:EG359 RS20055
gene id: 112234:EG359_RS20055
uniprot id: A0A1N7KCH0
names: Similarity
messages: Belongs to the DEAD box helicase family.

112234:EG359 RS13075
gene id: 112234:EG359_RS13075
uniprot id: A0A1N7JP53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

112234:EG359 RS07765
gene id: 112234:EG359_RS07765
uniprot id: A0A1N7I1Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

112234:EG359 RS09265
gene id: 112234:EG359_RS09265
uniprot id: A0A1N7I3P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

112234:EG359 RS02545
gene id: 112234:EG359_RS02545
uniprot id: A0A1N7IL28
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

112234:EG359 RS04200
gene id: 112234:EG359_RS04200
uniprot id: A0A1N7HWI0
names: Similarity
messages: Belongs to the peptidase M17 family.

112234:EG359 RS13430
gene id: 112234:EG359_RS13430
uniprot id: A0A1N7JTG8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS04095
gene id: 112234:EG359_RS04095
uniprot id: A0A1N7HWN8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

112234:EG359 RS19685
gene id: 112234:EG359_RS19685
uniprot id: A0A1N7J5S1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

112234:EG359 RS20585
gene id: 112234:EG359_RS20585
uniprot id: A0A1N7IC28
names: Similarity
messages: Belongs to the peptidase M13 family.

112234:EG359 RS20505
gene id: 112234:EG359_RS20505
uniprot id: A0A1N7IC26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

112234:EG359 RS00395
gene id: 112234:EG359_RS00395
uniprot id: A0A1N7IF21
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15695
gene id: 112234:EG359_RS15695
uniprot id: A0A1N7I9I3
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS14250
gene id: 112234:EG359_RS14250
uniprot id: A0A1N7I751
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS02135
gene id: 112234:EG359_RS02135
uniprot id: A0A1N7IMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

112234:EG359 RS10005
gene id: 112234:EG359_RS10005
uniprot id: A0A1N7I4U3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

112234:EG359 RS00280
gene id: 112234:EG359_RS00280
uniprot id: A0A3G6R982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

112234:EG359 RS02885
gene id: 112234:EG359_RS02885
uniprot id: A0A1N7HYC0
names: Similarity
messages: Belongs to the DEAD box helicase family.

112234:EG359 RS14060
gene id: 112234:EG359_RS14060
uniprot id: A0A1N7I6P2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS10435
gene id: 112234:EG359_RS10435
uniprot id: A0A1N7IG06
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS02835
gene id: 112234:EG359_RS02835
uniprot id: A0A1N7HYF2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

112234:EG359 RS19950
gene id: 112234:EG359_RS19950
uniprot id: A0A3G6RI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

112234:EG359 RS06960
gene id: 112234:EG359_RS06960
uniprot id: A0A1N7JB77
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

112234:EG359 RS04060
gene id: 112234:EG359_RS04060
uniprot id: A0A1N7HX13
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

112234:EG359 RS14520
gene id: 112234:EG359_RS14520
uniprot id: A0A1N7I7I1
names: Similarity
messages: Belongs to the UPF0102 family.

112234:EG359 RS20935
gene id: 112234:EG359_RS20935
uniprot id: A0A1N7ICT7
names: Similarity
messages: Belongs to the bacterial glucokinase family.

112234:EG359 RS19650
gene id: 112234:EG359_RS19650
uniprot id: A0A1N7J5L5
names: Function
messages: May be involved in the biogenesis of curli organelles.

112234:EG359 RS09450
gene id: 112234:EG359_RS09450
uniprot id: A0A1N7I3X8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09995
gene id: 112234:EG359_RS09995
uniprot id: A0A1N7I4U1
names: Cofactor
messages: Can also use Mn(2+) ion.

112234:EG359 RS00310
gene id: 112234:EG359_RS00310
uniprot id: A0A1N7IEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

112234:EG359 RS10485
gene id: 112234:EG359_RS10485
uniprot id: A0A1N7IG26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

112234:EG359 RS18115
gene id: 112234:EG359_RS18115
uniprot id: A0A1N7IYB2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

112234:EG359 RS11295
gene id: 112234:EG359_RS11295
uniprot id: A0A1N7IHC9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS11700
gene id: 112234:EG359_RS11700
uniprot id: A0A1N7IH78
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

112234:EG359 RS13725
gene id: 112234:EG359_RS13725
uniprot id: A0A1N7JX57
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

112234:EG359 RS02755
gene id: 112234:EG359_RS02755
uniprot id: A0A1N7HYI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

112234:EG359 RS21185
gene id: 112234:EG359_RS21185
uniprot id: A0A1N7ID25
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

112234:EG359 RS13555
gene id: 112234:EG359_RS13555
uniprot id: A0A1N7JV66
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS13495
gene id: 112234:EG359_RS13495
uniprot id: A0A3G6RDZ3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

112234:EG359 RS14580
gene id: 112234:EG359_RS14580
uniprot id: A0A1N7I7J5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS02185
gene id: 112234:EG359_RS02185
uniprot id: A0A1N7IMK9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS04220
gene id: 112234:EG359_RS04220
uniprot id: A0A1N7HWF9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

112234:EG359 RS08070
gene id: 112234:EG359_RS08070
uniprot id: A0A1N7JGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

112234:EG359 RS00735
gene id: 112234:EG359_RS00735
uniprot id: A0A1N7IT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

112234:EG359 RS08050
gene id: 112234:EG359_RS08050
uniprot id: A0A1N7JGK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS20130
gene id: 112234:EG359_RS20130
uniprot id: A0A1N7KDB1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

112234:EG359 RS07950
gene id: 112234:EG359_RS07950
uniprot id: A0A1N7I241
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

112234:EG359 RS13595
gene id: 112234:EG359_RS13595
uniprot id: A0A1N7JVN1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

112234:EG359 RS17070
gene id: 112234:EG359_RS17070
uniprot id: A0A1N7IAU4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

112234:EG359 RS18825
gene id: 112234:EG359_RS18825
uniprot id: A0A1N7J1S1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16715
gene id: 112234:EG359_RS16715
uniprot id: A0A1N7IAM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

112234:EG359 RS13395
gene id: 112234:EG359_RS13395
uniprot id: A0A1N7JSX5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

112234:EG359 RS08270
gene id: 112234:EG359_RS08270
uniprot id: A0A1N7JH63
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS14665
gene id: 112234:EG359_RS14665
uniprot id: A0A1N7I7T8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS20060
gene id: 112234:EG359_RS20060
uniprot id: A0A1N7KCH1
names: Similarity
messages: Belongs to the UPF0111 family.

112234:EG359 RS14590
gene id: 112234:EG359_RS14590
uniprot id: A0A1N7I7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

112234:EG359 RS08840
gene id: 112234:EG359_RS08840
uniprot id: A0A1N7I3D7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

112234:EG359 RS14775
gene id: 112234:EG359_RS14775
uniprot id: A0A1N7I7T1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS16670
gene id: 112234:EG359_RS16670
uniprot id: A0A1N7IAH6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

112234:EG359 RS00825
gene id: 112234:EG359_RS00825
uniprot id: A0A1N7ISU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16600
gene id: 112234:EG359_RS16600
uniprot id: A0A1N7IAE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

112234:EG359 RS07200
gene id: 112234:EG359_RS07200
uniprot id: A0A1N7JCB0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS03695
gene id: 112234:EG359_RS03695
uniprot id: A0A1N7HX77
names: Similarity
messages: Belongs to the ribF family.

112234:EG359 RS10735
gene id: 112234:EG359_RS10735
uniprot id: A0A1N7IGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

112234:EG359 RS06750
gene id: 112234:EG359_RS06750
uniprot id: A0A1N7J9U5
names: Subcellular Location Annotation
messages: Cell inner membrane

112234:EG359 RS15390
gene id: 112234:EG359_RS15390
uniprot id: A0A1N7I901
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

112234:EG359 RS22160
gene id: 112234:EG359_RS22160
uniprot id: A0A3G6RJR9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

112234:EG359 RS00865
gene id: 112234:EG359_RS00865
uniprot id: A0A1N7ISP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS11920
gene id: 112234:EG359_RS11920
uniprot id: A0A1N7IHF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

112234:EG359 RS19690
gene id: 112234:EG359_RS19690
uniprot id: A0A1N7J5M0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS14805
gene id: 112234:EG359_RS14805
uniprot id: A0A1N7I7V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09190
gene id: 112234:EG359_RS09190
uniprot id: A0A1N7I3I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

112234:EG359 RS15080
gene id: 112234:EG359_RS15080
uniprot id: A0A1N7I899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

112234:EG359 RS03120
gene id: 112234:EG359_RS03120
uniprot id: A0A1N7HY74
names: Similarity
messages: Belongs to the IucA/IucC family.

112234:EG359 RS00285
gene id: 112234:EG359_RS00285
uniprot id: A0A1N7IFB8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS19915
gene id: 112234:EG359_RS19915
uniprot id: A0A1N7KIV0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

112234:EG359 RS16355
gene id: 112234:EG359_RS16355
uniprot id: A0A1N7IA84
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS19285
gene id: 112234:EG359_RS19285
uniprot id: A0A1N7J421
names: Similarity
messages: Belongs to the pirin family.

112234:EG359 RS19820
gene id: 112234:EG359_RS19820
uniprot id: A0A1N7J6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

112234:EG359 RS14115
gene id: 112234:EG359_RS14115
uniprot id: A0A1N7I6V7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS08775
gene id: 112234:EG359_RS08775
uniprot id: A0A1N7I389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

112234:EG359 RS14415
gene id: 112234:EG359_RS14415
uniprot id: A0A1N7I7F3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

112234:EG359 RS14525
gene id: 112234:EG359_RS14525
uniprot id: A0A1N7I7H6
names: Similarity
messages: Belongs to the peptidase S66 family.

112234:EG359 RS10580
gene id: 112234:EG359_RS10580
uniprot id: A0A1N7IG68
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

112234:EG359 RS21090
gene id: 112234:EG359_RS21090
uniprot id: A0A1N7ID29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

112234:EG359 RS09810
gene id: 112234:EG359_RS09810
uniprot id: A0A3G6RDL8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS19300
gene id: 112234:EG359_RS19300
uniprot id: A0A1N7J3Y1
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS10000
gene id: 112234:EG359_RS10000
uniprot id: A0A1N7I4Q6
names: Similarity
messages: Belongs to the malate synthase family.

112234:EG359 RS07315
gene id: 112234:EG359_RS07315
uniprot id: A0A1N7JCQ9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

112234:EG359 RS22100
gene id: 112234:EG359_RS22100
uniprot id: A0A1N7IEJ1
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

112234:EG359 RS02530
gene id: 112234:EG359_RS02530
uniprot id: A0A1N7IL39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

112234:EG359 RS11800
gene id: 112234:EG359_RS11800
uniprot id: A0A1N7IHB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

112234:EG359 RS10740
gene id: 112234:EG359_RS10740
uniprot id: A0A3G6RGE0
names: Similarity
messages: Belongs to the threonine synthase family.

112234:EG359 RS01715
gene id: 112234:EG359_RS01715
uniprot id: A0A1N7IPF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

112234:EG359 RS13305
gene id: 112234:EG359_RS13305
uniprot id: A0A1N7JS49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

112234:EG359 RS00010
gene id: 112234:EG359_RS00010
uniprot id: A0A3G6R1P4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

112234:EG359 RS16580
gene id: 112234:EG359_RS16580
uniprot id: A0A1N7IAD4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

112234:EG359 RS01785
gene id: 112234:EG359_RS01785
uniprot id: A0A1N7IP77
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04090
gene id: 112234:EG359_RS04090
uniprot id: A0A1N7HWM0
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS18360
gene id: 112234:EG359_RS18360
uniprot id: A0A1N7IZL7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

112234:EG359 RS10795
gene id: 112234:EG359_RS10795
uniprot id: A0A1N7IGI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS21725
gene id: 112234:EG359_RS21725
uniprot id: A0A1N7IDW2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16965
gene id: 112234:EG359_RS16965
uniprot id: A0A1N7IAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

112234:EG359 RS17390
gene id: 112234:EG359_RS17390
uniprot id: A0A1N7IB66
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS14535
gene id: 112234:EG359_RS14535
uniprot id: A0A1N7I7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

112234:EG359 RS14975
gene id: 112234:EG359_RS14975
uniprot id: A0A1N7I840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

112234:EG359 RS03550
gene id: 112234:EG359_RS03550
uniprot id: A0A1N7HXH7
names: Similarity
messages: Belongs to the DtxR/MntR family.

112234:EG359 RS01455
gene id: 112234:EG359_RS01455
uniprot id: A0A1N7IQM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

112234:EG359 RS14285
gene id: 112234:EG359_RS14285
uniprot id: A0A1N7I743
names: Similarity
messages: Belongs to the Vsr family.

112234:EG359 RS19410
gene id: 112234:EG359_RS19410
uniprot id: A0A1N7J4G5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

112234:EG359 RS21985
gene id: 112234:EG359_RS21985
uniprot id: A0A1N7IEB8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS17685
gene id: 112234:EG359_RS17685
uniprot id: A0A1N7K6K1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

112234:EG359 RS11310
gene id: 112234:EG359_RS11310
uniprot id: A0A1N7IGX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS13525
gene id: 112234:EG359_RS13525
uniprot id: A0A1N7JUT0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

112234:EG359 RS17080
gene id: 112234:EG359_RS17080
uniprot id: A0A1N7IAV1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

112234:EG359 RS14725
gene id: 112234:EG359_RS14725
uniprot id: A0A1N7I7R9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

112234:EG359 RS15015
gene id: 112234:EG359_RS15015
uniprot id: A0A1N7I867
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

112234:EG359 RS07590
gene id: 112234:EG359_RS07590
uniprot id: A0A1N7JED2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

112234:EG359 RS04410
gene id: 112234:EG359_RS04410
uniprot id: A0A1N7HWD4
names: Similarity
messages: Belongs to the CvfB family.

112234:EG359 RS16115
gene id: 112234:EG359_RS16115
uniprot id: A0A1N7I9S5
names: Similarity
messages: Belongs to the asparagine synthetase family.

112234:EG359 RS05325
gene id: 112234:EG359_RS05325
uniprot id: A0A1N7HUD5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

112234:EG359 RS01460
gene id: 112234:EG359_RS01460
uniprot id: A0A1N7IQB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

112234:EG359 RS18310
gene id: 112234:EG359_RS18310
uniprot id: A0A1N7IZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS09790
gene id: 112234:EG359_RS09790
uniprot id: A0A1N7I4G3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

112234:EG359 RS21705
gene id: 112234:EG359_RS21705
uniprot id: A0A1N7IDX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

112234:EG359 RS21640
gene id: 112234:EG359_RS21640
uniprot id: A0A1N7IDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS21830
gene id: 112234:EG359_RS21830
uniprot id: A0A1N7IE71
names: Similarity
messages: Belongs to the OsmC/Ohr family.

112234:EG359 RS10675
gene id: 112234:EG359_RS10675
uniprot id: A0A1N7IGA3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS01945
gene id: 112234:EG359_RS01945
uniprot id: A0A1N7INS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS01440
gene id: 112234:EG359_RS01440
uniprot id: A0A1N7IQD2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS10510
gene id: 112234:EG359_RS10510
uniprot id: A0A1N7IG33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

112234:EG359 RS18765
gene id: 112234:EG359_RS18765
uniprot id: A0A1N7J1E3
names: Similarity
messages: Belongs to the MQO family.

112234:EG359 RS07700
gene id: 112234:EG359_RS07700
uniprot id: A0A1N7JEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

112234:EG359 RS00070
gene id: 112234:EG359_RS00070
uniprot id: A0A1N7IER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS09455
gene id: 112234:EG359_RS09455
uniprot id: A0A1N7I402
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15415
gene id: 112234:EG359_RS15415
uniprot id: A0A1N7I8U2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

112234:EG359 RS21475
gene id: 112234:EG359_RS21475
uniprot id: A0A1N7IDM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

112234:EG359 RS15585
gene id: 112234:EG359_RS15585
uniprot id: A0A1N7I9D4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

112234:EG359 RS09085
gene id: 112234:EG359_RS09085
uniprot id: A0A1N7I3I5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

112234:EG359 RS15590
gene id: 112234:EG359_RS15590
uniprot id: A0A1N7I933
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

112234:EG359 RS00350
gene id: 112234:EG359_RS00350
uniprot id: A0A1N7IFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

112234:EG359 RS03320
gene id: 112234:EG359_RS03320
uniprot id: A0A1N7HXK9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

112234:EG359 RS22050
gene id: 112234:EG359_RS22050
uniprot id: A0A1N7IEE7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS05520
gene id: 112234:EG359_RS05520
uniprot id: A0A1N7HU96
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS04710
gene id: 112234:EG359_RS04710
uniprot id: A0A1N7HVU9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

112234:EG359 RS18370
gene id: 112234:EG359_RS18370
uniprot id: A0A1N7IZJ3
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

112234:EG359 RS02100
gene id: 112234:EG359_RS02100
uniprot id: A0A1N7IMY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS15810
gene id: 112234:EG359_RS15810
uniprot id: A0A1N7I9F5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

112234:EG359 RS12860
gene id: 112234:EG359_RS12860
uniprot id: A0A1N7JLR4
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14625
gene id: 112234:EG359_RS14625
uniprot id: A0A1N7I7U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

112234:EG359 RS01665
gene id: 112234:EG359_RS01665
uniprot id: A0A1N7IPN6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

112234:EG359 RS07075
gene id: 112234:EG359_RS07075
uniprot id: A0A1N7JBK5
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS12825
gene id: 112234:EG359_RS12825
uniprot id: A0A1N7JL88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

112234:EG359 RS01425
gene id: 112234:EG359_RS01425
uniprot id: A0A1N7IQH9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

112234:EG359 RS01535
gene id: 112234:EG359_RS01535
uniprot id: A0A1N7IQ44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

112234:EG359 RS17940
gene id: 112234:EG359_RS17940
uniprot id: A0A1N7K3B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

112234:EG359 RS15230
gene id: 112234:EG359_RS15230
uniprot id: A0A1N7I8P4
names: Similarity
messages: Belongs to the DprA/Smf family.

112234:EG359 RS16195
gene id: 112234:EG359_RS16195
uniprot id: A0A1N7I9W9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

112234:EG359 RS04655
gene id: 112234:EG359_RS04655
uniprot id: A0A1N7HVL6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04240
gene id: 112234:EG359_RS04240
uniprot id: A0A1N7HWC0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

112234:EG359 RS12100
gene id: 112234:EG359_RS12100
uniprot id: A0A1N7IHJ0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

112234:EG359 RS14870
gene id: 112234:EG359_RS14870
uniprot id: A0A1N7I828
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

112234:EG359 RS11675
gene id: 112234:EG359_RS11675
uniprot id: A0A3G6R812
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

112234:EG359 RS02910
gene id: 112234:EG359_RS02910
uniprot id: A0A1N7HYA2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS00530
gene id: 112234:EG359_RS00530
uniprot id: A0A1N7IFE1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

112234:EG359 RS11455
gene id: 112234:EG359_RS11455
uniprot id: A0A1N7IH43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

112234:EG359 RS00305
gene id: 112234:EG359_RS00305
uniprot id: A0A1N7IEZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

112234:EG359 RS14605
gene id: 112234:EG359_RS14605
uniprot id: A0A1N7I7L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

112234:EG359 RS17800
gene id: 112234:EG359_RS17800
uniprot id: A0A1N7K565
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

112234:EG359 RS03355
gene id: 112234:EG359_RS03355
uniprot id: A0A1N7HXX3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

112234:EG359 RS19130
gene id: 112234:EG359_RS19130
uniprot id: A0A1N7J2V3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16410
gene id: 112234:EG359_RS16410
uniprot id: A0A3G6RBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS05680
gene id: 112234:EG359_RS05680
uniprot id: A0A1N7HTS5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

112234:EG359 RS15630
gene id: 112234:EG359_RS15630
uniprot id: A0A1N7I973
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

112234:EG359 RS12885
gene id: 112234:EG359_RS12885
uniprot id: A0A1N7JM37
names: Similarity
messages: Belongs to the peptidase M16 family.

112234:EG359 RS14430
gene id: 112234:EG359_RS14430
uniprot id: A0A1N7I7J7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

112234:EG359 RS03685
gene id: 112234:EG359_RS03685
uniprot id: A0A1N7HXG6
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

112234:EG359 RS13880
gene id: 112234:EG359_RS13880
uniprot id: A0A1N7JZ54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

112234:EG359 RS18320
gene id: 112234:EG359_RS18320
uniprot id: A0A1N7IZ99
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09615
gene id: 112234:EG359_RS09615
uniprot id: A0A1N7I450
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

112234:EG359 RS11660
gene id: 112234:EG359_RS11660
uniprot id: A0A1N7IHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

112234:EG359 RS18200
gene id: 112234:EG359_RS18200
uniprot id: A0A1N7IYM0
names: Similarity
messages: Belongs to the nitroreductase family.

112234:EG359 RS02540
gene id: 112234:EG359_RS02540
uniprot id: A0A1N7ILC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS21695
gene id: 112234:EG359_RS21695
uniprot id: A0A1N7IE12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

112234:EG359 RS12230
gene id: 112234:EG359_RS12230
uniprot id: A0A1N7IHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

112234:EG359 RS01935
gene id: 112234:EG359_RS01935
uniprot id: A0A1N7INN5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

112234:EG359 RS06970
gene id: 112234:EG359_RS06970
uniprot id: A0A3G6R3K9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04010
gene id: 112234:EG359_RS04010
uniprot id: A0A1N7HWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

112234:EG359 RS05815
gene id: 112234:EG359_RS05815
uniprot id: A0A1N7HTI0
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS05920
gene id: 112234:EG359_RS05920
uniprot id: A0A1N7HTK2
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS21385
gene id: 112234:EG359_RS21385
uniprot id: A0A1N7IDI2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

112234:EG359 RS04715
gene id: 112234:EG359_RS04715
uniprot id: A0A1N7HVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

112234:EG359 RS09220
gene id: 112234:EG359_RS09220
uniprot id: A0A1N7I3I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

112234:EG359 RS12280
gene id: 112234:EG359_RS12280
uniprot id: A0A1N7II49
names: Similarity
messages: Belongs to the peptidase C40 family.

112234:EG359 RS16730
gene id: 112234:EG359_RS16730
uniprot id: A0A1N7IAP6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

112234:EG359 RS12545
gene id: 112234:EG359_RS12545
uniprot id: A0A1N7II85
names: Similarity
messages: Belongs to the group II decarboxylase family.

112234:EG359 RS08855
gene id: 112234:EG359_RS08855
uniprot id: A0A1N7I3A9
names: Subcellular Location Annotation
messages: Secreted

112234:EG359 RS18355
gene id: 112234:EG359_RS18355
uniprot id: A0A1N7IZA9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

112234:EG359 RS12780
gene id: 112234:EG359_RS12780
uniprot id: A0A1N7JKX0
names: Similarity
messages: Belongs to the Skp family.

112234:EG359 RS08730
gene id: 112234:EG359_RS08730
uniprot id: A0A1N7I382
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

112234:EG359 RS11655
gene id: 112234:EG359_RS11655
uniprot id: A0A1N7IH66
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

112234:EG359 RS12525
gene id: 112234:EG359_RS12525
uniprot id: A0A1N7IIA2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09725
gene id: 112234:EG359_RS09725
uniprot id: A0A1N7I4I7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

112234:EG359 RS03525
gene id: 112234:EG359_RS03525
uniprot id: A0A1N7HXI4
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14495
gene id: 112234:EG359_RS14495
uniprot id: A0A1N7I7H7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

112234:EG359 RS21735
gene id: 112234:EG359_RS21735
uniprot id: A0A1N7IDX8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS05140
gene id: 112234:EG359_RS05140
uniprot id: A0A1N7HUU4
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS20185
gene id: 112234:EG359_RS20185
uniprot id: A0A1N7KDX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

112234:EG359 RS16560
gene id: 112234:EG359_RS16560
uniprot id: A0A1N7IAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

112234:EG359 RS15290
gene id: 112234:EG359_RS15290
uniprot id: A0A1N7I8U7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

112234:EG359 RS09385
gene id: 112234:EG359_RS09385
uniprot id: A0A1N7I3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS19880
gene id: 112234:EG359_RS19880
uniprot id: A0A1N7KII9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

112234:EG359 RS03115
gene id: 112234:EG359_RS03115
uniprot id: A0A1N7HY44
names: Similarity
messages: Belongs to the group II decarboxylase family.

112234:EG359 RS00910
gene id: 112234:EG359_RS00910
uniprot id: A0A1N7ISG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

112234:EG359 RS06070
gene id: 112234:EG359_RS06070
uniprot id: A0A1N7HT77
names: Similarity
messages: Belongs to the type IA topoisomerase family.

112234:EG359 RS08405
gene id: 112234:EG359_RS08405
uniprot id: A0A1N7I2R8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

112234:EG359 RS14125
gene id: 112234:EG359_RS14125
uniprot id: A0A1N7I6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

112234:EG359 RS17440
gene id: 112234:EG359_RS17440
uniprot id: A0A1N7K9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

112234:EG359 RS11835
gene id: 112234:EG359_RS11835
uniprot id: A0A1N7IHB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

112234:EG359 RS14145
gene id: 112234:EG359_RS14145
uniprot id: A0A1N7I6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

112234:EG359 RS05915
gene id: 112234:EG359_RS05915
uniprot id: A0A1N7HTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS19885
gene id: 112234:EG359_RS19885
uniprot id: A0A1N7KI80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

112234:EG359 RS00435
gene id: 112234:EG359_RS00435
uniprot id: A0A1N7IFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

112234:EG359 RS13735
gene id: 112234:EG359_RS13735
uniprot id: A0A1N7JXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

112234:EG359 RS09640
gene id: 112234:EG359_RS09640
uniprot id: A0A1N7I491
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

112234:EG359 RS14515
gene id: 112234:EG359_RS14515
uniprot id: A0A1N7I7K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS17790
gene id: 112234:EG359_RS17790
uniprot id: A0A1N7K5G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS02745
gene id: 112234:EG359_RS02745
uniprot id: A0A1N7HYM1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

112234:EG359 RS16710
gene id: 112234:EG359_RS16710
uniprot id: A0A1N7IAI5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

112234:EG359 RS10380
gene id: 112234:EG359_RS10380
uniprot id: A0A1N7IFZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

112234:EG359 RS04185
gene id: 112234:EG359_RS04185
uniprot id: A0A1N7HWH1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

112234:EG359 RS01550
gene id: 112234:EG359_RS01550
uniprot id: A0A1N7IQ06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

112234:EG359 RS00605
gene id: 112234:EG359_RS00605
uniprot id: A0A1N7ITT6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

112234:EG359 RS05105
gene id: 112234:EG359_RS05105
uniprot id: A0A1N7HUR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

112234:EG359 RS04245
gene id: 112234:EG359_RS04245
uniprot id: A0A3G6RBR2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

112234:EG359 RS21930
gene id: 112234:EG359_RS21930
uniprot id: A0A1N7IEC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS14715
gene id: 112234:EG359_RS14715
uniprot id: A0A1N7I7Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04025
gene id: 112234:EG359_RS04025
uniprot id: A0A1N7HWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

112234:EG359 RS00800
gene id: 112234:EG359_RS00800
uniprot id: A0A1N7ITB0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

112234:EG359 RS08420
gene id: 112234:EG359_RS08420
uniprot id: A0A1N7I2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16240
gene id: 112234:EG359_RS16240
uniprot id: A0A1N7IA01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

112234:EG359 RS07705
gene id: 112234:EG359_RS07705
uniprot id: A0A3G6REA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

112234:EG359 RS15055
gene id: 112234:EG359_RS15055
uniprot id: A0A1N7I883
names: Similarity
messages: Belongs to the universal stress protein A family.

112234:EG359 RS07125
gene id: 112234:EG359_RS07125
uniprot id: A0A1N7JBT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS19575
gene id: 112234:EG359_RS19575
uniprot id: A0A1N7J503
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

112234:EG359 RS02990
gene id: 112234:EG359_RS02990
uniprot id: A0A1N7HY23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS08325
gene id: 112234:EG359_RS08325
uniprot id: A0A1N7I2L6
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS12075
gene id: 112234:EG359_RS12075
uniprot id: A0A1N7IHY7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

112234:EG359 RS00445
gene id: 112234:EG359_RS00445
uniprot id: A0A1N7IF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

112234:EG359 RS09825
gene id: 112234:EG359_RS09825
uniprot id: A0A1N7I4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

112234:EG359 RS19295
gene id: 112234:EG359_RS19295
uniprot id: A0A1N7J3S9
names: Similarity
messages: Belongs to the pirin family.

112234:EG359 RS08870
gene id: 112234:EG359_RS08870
uniprot id: A0A1N7I3H3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

112234:EG359 RS17045
gene id: 112234:EG359_RS17045
uniprot id: A0A1N7IAU2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

112234:EG359 RS20660
gene id: 112234:EG359_RS20660
uniprot id: A0A1N7IC78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

112234:EG359 RS16270
gene id: 112234:EG359_RS16270
uniprot id: A0A1N7IA07
names: Similarity
messages: Belongs to the fabD family.

112234:EG359 RS05080
gene id: 112234:EG359_RS05080
uniprot id: A0A1N7HUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS17950
gene id: 112234:EG359_RS17950
uniprot id: A0A1N7K362
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

112234:EG359 RS00355
gene id: 112234:EG359_RS00355
uniprot id: A0A1N7IF01
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

112234:EG359 RS15625
gene id: 112234:EG359_RS15625
uniprot id: A0A1N7I982
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04725
gene id: 112234:EG359_RS04725
uniprot id: A0A1N7HVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS09440
gene id: 112234:EG359_RS09440
uniprot id: A0A1N7I401
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15265
gene id: 112234:EG359_RS15265
uniprot id: A0A1N7I8L2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

112234:EG359 RS02940
gene id: 112234:EG359_RS02940
uniprot id: A0A1N7HY72
names: Similarity
messages: Belongs to the DapA family.

112234:EG359 RS04485
gene id: 112234:EG359_RS04485
uniprot id: A0A1N7HVW9
names: Similarity
messages: Belongs to the peptidase S13 family.

112234:EG359 RS05620
gene id: 112234:EG359_RS05620
uniprot id: A0A1N7HTV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

112234:EG359 RS21215
gene id: 112234:EG359_RS21215
uniprot id: A0A1N7ID84
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS19490
gene id: 112234:EG359_RS19490
uniprot id: A0A1N7J4K9
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

112234:EG359 RS04395
gene id: 112234:EG359_RS04395
uniprot id: A0A1N7HW33
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS13450
gene id: 112234:EG359_RS13450
uniprot id: A0A1N7JU30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

112234:EG359 RS09610
gene id: 112234:EG359_RS09610
uniprot id: A0A1N7I455
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

112234:EG359 RS19310
gene id: 112234:EG359_RS19310
uniprot id: A0A1N7J3V4
names: Similarity
messages: Belongs to the asparagine synthetase family.

112234:EG359 RS15840
gene id: 112234:EG359_RS15840
uniprot id: A0A1N7I9N2
names: Similarity
messages: Belongs to the LOG family.

112234:EG359 RS19580
gene id: 112234:EG359_RS19580
uniprot id: A0A1N7J5D9
names: Similarity
messages: Belongs to the peptidase S33 family.

112234:EG359 RS13245
gene id: 112234:EG359_RS13245
uniprot id: A0A1N7JRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

112234:EG359 RS11850
gene id: 112234:EG359_RS11850
uniprot id: A0A1N7IHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

112234:EG359 RS03690
gene id: 112234:EG359_RS03690
uniprot id: A0A1N7HX58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

112234:EG359 RS19150
gene id: 112234:EG359_RS19150
uniprot id: A0A1N7J2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

112234:EG359 RS18380
gene id: 112234:EG359_RS18380
uniprot id: A0A1N7IZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS14110
gene id: 112234:EG359_RS14110
uniprot id: A0A1N7I6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

112234:EG359 RS08755
gene id: 112234:EG359_RS08755
uniprot id: A0A1N7I379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

112234:EG359 RS00045
gene id: 112234:EG359_RS00045
uniprot id: A0A1N7IEQ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS09115
gene id: 112234:EG359_RS09115
uniprot id: A0A1N7I3J2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

112234:EG359 RS16295
gene id: 112234:EG359_RS16295
uniprot id: A0A1N7IA87
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS21710
gene id: 112234:EG359_RS21710
uniprot id: A0A1N7IDW6
names: Similarity
messages: Belongs to the peptidase S13 family.

112234:EG359 RS03225
gene id: 112234:EG359_RS03225
uniprot id: A0A1N7HXQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS13840
gene id: 112234:EG359_RS13840
uniprot id: A0A1N7JYM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

112234:EG359 RS03435
gene id: 112234:EG359_RS03435
uniprot id: A0A1N7HXH0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

112234:EG359 RS16280
gene id: 112234:EG359_RS16280
uniprot id: A0A1N7IA18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

112234:EG359 RS01390
gene id: 112234:EG359_RS01390
uniprot id: A0A1N7IQJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS18045
gene id: 112234:EG359_RS18045
uniprot id: A0A1N7IY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

112234:EG359 RS09785
gene id: 112234:EG359_RS09785
uniprot id: A0A1N7I4L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

112234:EG359 RS05470
gene id: 112234:EG359_RS05470
uniprot id: A0A1N7HU62
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS07380
gene id: 112234:EG359_RS07380
uniprot id: A0A1N7I1F9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS05010
gene id: 112234:EG359_RS05010
uniprot id: A0A1N7HUX4
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS06780
gene id: 112234:EG359_RS06780
uniprot id: A0A1N7I0G3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS13485
gene id: 112234:EG359_RS13485
uniprot id: A0A1N7JUB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

112234:EG359 RS08425
gene id: 112234:EG359_RS08425
uniprot id: A0A1N7I2S8
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS18805
gene id: 112234:EG359_RS18805
uniprot id: A0A1N7J1M4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

112234:EG359 RS09845
gene id: 112234:EG359_RS09845
uniprot id: A0A1N7I4E4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

112234:EG359 RS14560
gene id: 112234:EG359_RS14560
uniprot id: A0A1N7I7L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

112234:EG359 RS10655
gene id: 112234:EG359_RS10655
uniprot id: A0A1N7IGF0
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS05600
gene id: 112234:EG359_RS05600
uniprot id: A0A1N7HTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

112234:EG359 RS16000
gene id: 112234:EG359_RS16000
uniprot id: A0A1N7I9M1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

112234:EG359 RS00135
gene id: 112234:EG359_RS00135
uniprot id: A0A1N7IER0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

112234:EG359 RS18600
gene id: 112234:EG359_RS18600
uniprot id: A0A1N7J0P7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

112234:EG359 RS15250
gene id: 112234:EG359_RS15250
uniprot id: A0A3G6RGJ1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

112234:EG359 RS15110
gene id: 112234:EG359_RS15110
uniprot id: A0A1N7I8H6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

112234:EG359 RS20820
gene id: 112234:EG359_RS20820
uniprot id: A0A1N7ICL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

112234:EG359 RS20240
gene id: 112234:EG359_RS20240
uniprot id: A0A1N7KEM8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS05280
gene id: 112234:EG359_RS05280
uniprot id: A0A1N7HUP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS07655
gene id: 112234:EG359_RS07655
uniprot id: A0A1N7I1W5
names: Similarity
messages: Belongs to the peptidase M24B family.

112234:EG359 RS18365
gene id: 112234:EG359_RS18365
uniprot id: A0A1N7IZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS14600
gene id: 112234:EG359_RS14600
uniprot id: A0A1N7I7M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

112234:EG359 RS16745
gene id: 112234:EG359_RS16745
uniprot id: A0A1N7IAL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS11565
gene id: 112234:EG359_RS11565
uniprot id: A0A3G6RDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

112234:EG359 RS11435
gene id: 112234:EG359_RS11435
uniprot id: A0A1N7IH53
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS07975
gene id: 112234:EG359_RS07975
uniprot id: A0A1N7JG90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS00780
gene id: 112234:EG359_RS00780
uniprot id: A0A1N7IT16
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

112234:EG359 RS08745
gene id: 112234:EG359_RS08745
uniprot id: A0A1N7I381
names: Similarity
messages: Belongs to the peptidase C59 family.

112234:EG359 RS15900
gene id: 112234:EG359_RS15900
uniprot id: A0A1N7I9I9
names: Similarity
messages: Belongs to the nitroreductase family.

112234:EG359 RS16780
gene id: 112234:EG359_RS16780
uniprot id: A0A1N7IAL7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS04465
gene id: 112234:EG359_RS04465
uniprot id: A0A3G6R2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

112234:EG359 RS03350
gene id: 112234:EG359_RS03350
uniprot id: A0A1N7HXP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

112234:EG359 RS00005
gene id: 112234:EG359_RS00005
uniprot id: A0A3G6R599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

112234:EG359 RS15070
gene id: 112234:EG359_RS15070
uniprot id: A0A1N7I893
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS08120
gene id: 112234:EG359_RS08120
uniprot id: A0A1N7I2B8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16790
gene id: 112234:EG359_RS16790
uniprot id: A0A1N7IAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

112234:EG359 RS16760
gene id: 112234:EG359_RS16760
uniprot id: A0A1N7IAM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

112234:EG359 RS21620
gene id: 112234:EG359_RS21620
uniprot id: A0A1N7IDX9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

112234:EG359 RS12155
gene id: 112234:EG359_RS12155
uniprot id: A0A1N7IHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

112234:EG359 RS09410
gene id: 112234:EG359_RS09410
uniprot id: A0A1N7I3U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS10880
gene id: 112234:EG359_RS10880
uniprot id: A0A1N7IGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS07840
gene id: 112234:EG359_RS07840
uniprot id: A0A1N7JFM8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS12640
gene id: 112234:EG359_RS12640
uniprot id: A0A1N7III6
names: Similarity
messages: Belongs to the EPSP synthase family.

112234:EG359 RS11270
gene id: 112234:EG359_RS11270
uniprot id: A0A3G6RF42
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS20690
gene id: 112234:EG359_RS20690
uniprot id: A0A3G6RJ04
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS02550
gene id: 112234:EG359_RS02550
uniprot id: A0A1N7ILB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

112234:EG359 RS07270
gene id: 112234:EG359_RS07270
uniprot id: A0A1N7JCK0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

112234:EG359 RS11305
gene id: 112234:EG359_RS11305
uniprot id: A0A3G6RB31
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS07675
gene id: 112234:EG359_RS07675
uniprot id: A0A1N7I201
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS21145
gene id: 112234:EG359_RS21145
uniprot id: A0A1N7ID04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS11620
gene id: 112234:EG359_RS11620
uniprot id: A0A1N7IHC2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS12485
gene id: 112234:EG359_RS12485
uniprot id: A0A1N7II26
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS13830
gene id: 112234:EG359_RS13830
uniprot id: A0A1N7JYG7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

112234:EG359 RS09215
gene id: 112234:EG359_RS09215
uniprot id: A0A1N7I3P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

112234:EG359 RS10845
gene id: 112234:EG359_RS10845
uniprot id: A0A1N7IGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

112234:EG359 RS15775
gene id: 112234:EG359_RS15775
uniprot id: A0A1N7I9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

112234:EG359 RS05850
gene id: 112234:EG359_RS05850
uniprot id: A0A3G6R7E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

112234:EG359 RS18920
gene id: 112234:EG359_RS18920
uniprot id: A0A1N7J1X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS04865
gene id: 112234:EG359_RS04865
uniprot id: A0A1N7HV88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

112234:EG359 RS08925
gene id: 112234:EG359_RS08925
uniprot id: A0A1N7I3D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

112234:EG359 RS16660
gene id: 112234:EG359_RS16660
uniprot id: A0A1N7IAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

112234:EG359 RS16735
gene id: 112234:EG359_RS16735
uniprot id: A0A1N7IAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

112234:EG359 RS21140
gene id: 112234:EG359_RS21140
uniprot id: A0A1N7ICZ6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS16350
gene id: 112234:EG359_RS16350
uniprot id: A0A1N7IA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS05385
gene id: 112234:EG359_RS05385
uniprot id: A0A1N7HU94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

112234:EG359 RS17175
gene id: 112234:EG359_RS17175
uniprot id: A0A1N7IB88
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

112234:EG359 RS01270
gene id: 112234:EG359_RS01270
uniprot id: A0A1N7IR12
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

112234:EG359 RS18340
gene id: 112234:EG359_RS18340
uniprot id: A0A1N7IZI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

112234:EG359 RS19160
gene id: 112234:EG359_RS19160
uniprot id: A0A1N7J3E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

112234:EG359 RS20040
gene id: 112234:EG359_RS20040
uniprot id: A0A1N7KCA3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01575
gene id: 112234:EG359_RS01575
uniprot id: A0A1N7IPY2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS13815
gene id: 112234:EG359_RS13815
uniprot id: A0A1N7JY89
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS16785
gene id: 112234:EG359_RS16785
uniprot id: A0A1N7IAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

112234:EG359 RS13130
gene id: 112234:EG359_RS13130
uniprot id: A0A1N7JPM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

112234:EG359 RS13985
gene id: 112234:EG359_RS13985
uniprot id: A0A1N7I6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS03935
gene id: 112234:EG359_RS03935
uniprot id: A0A1N7HXA1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

112234:EG359 RS00470
gene id: 112234:EG359_RS00470
uniprot id: A0A1N7IF64
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS04780
gene id: 112234:EG359_RS04780
uniprot id: A0A1N7HVH8
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

112234:EG359 RS21885
gene id: 112234:EG359_RS21885
uniprot id: A0A1N7IE41
names: Similarity
messages: Belongs to the TrpC family.

112234:EG359 RS09820
gene id: 112234:EG359_RS09820
uniprot id: A0A1N7I4H6
names: Similarity
messages: Belongs to the Fur family.

112234:EG359 RS16885
gene id: 112234:EG359_RS16885
uniprot id: A0A1N7IAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

112234:EG359 RS07355
gene id: 112234:EG359_RS07355
uniprot id: A0A1N7JD39
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

112234:EG359 RS14545
gene id: 112234:EG359_RS14545
uniprot id: A0A1N7I7J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS18850
gene id: 112234:EG359_RS18850
uniprot id: A0A1N7J1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

112234:EG359 RS21870
gene id: 112234:EG359_RS21870
uniprot id: A0A1N7IE48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

112234:EG359 RS16495
gene id: 112234:EG359_RS16495
uniprot id: A0A1N7IAC9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

112234:EG359 RS12120
gene id: 112234:EG359_RS12120
uniprot id: A0A1N7IHT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

112234:EG359 RS06500
gene id: 112234:EG359_RS06500
uniprot id: A0A1N7HSH8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

112234:EG359 RS10830
gene id: 112234:EG359_RS10830
uniprot id: A0A1N7IGM3
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

112234:EG359 RS01650
gene id: 112234:EG359_RS01650
uniprot id: A0A1N7IPP5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

112234:EG359 RS21335
gene id: 112234:EG359_RS21335
uniprot id: A0A1N7IDG0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

112234:EG359 RS11555
gene id: 112234:EG359_RS11555
uniprot id: A0A1N7IH77
names: Similarity
messages: Belongs to the DinB family.

112234:EG359 RS04930
gene id: 112234:EG359_RS04930
uniprot id: A0A1N7HVB4
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

112234:EG359 RS12305
gene id: 112234:EG359_RS12305
uniprot id: A0A1N7IHW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

112234:EG359 RS22065
gene id: 112234:EG359_RS22065
uniprot id: A0A1N7IEE6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

112234:EG359 RS12165
gene id: 112234:EG359_RS12165
uniprot id: A0A1N7IHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

112234:EG359 RS19890
gene id: 112234:EG359_RS19890
uniprot id: A0A1N7KI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

112234:EG359 RS13605
gene id: 112234:EG359_RS13605
uniprot id: A0A1N7JVR2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS08630
gene id: 112234:EG359_RS08630
uniprot id: A0A1N7I322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

112234:EG359 RS09205
gene id: 112234:EG359_RS09205
uniprot id: A0A1N7I3N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

112234:EG359 RS00680
gene id: 112234:EG359_RS00680
uniprot id: A0A1N7ITI2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS02500
gene id: 112234:EG359_RS02500
uniprot id: A0A1N7IL73
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

112234:EG359 RS13000
gene id: 112234:EG359_RS13000
uniprot id: A0A1N7JN23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

112234:EG359 RS07935
gene id: 112234:EG359_RS07935
uniprot id: A0A1N7JFY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

112234:EG359 RS11325
gene id: 112234:EG359_RS11325
uniprot id: A0A1N7IH20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

112234:EG359 RS11600
gene id: 112234:EG359_RS11600
uniprot id: A0A1N7IH88
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14575
gene id: 112234:EG359_RS14575
uniprot id: A0A1N7I7J9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

112234:EG359 RS18165
gene id: 112234:EG359_RS18165
uniprot id: A0A1N7IYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

112234:EG359 RS14965
gene id: 112234:EG359_RS14965
uniprot id: A0A1N7I895
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

112234:EG359 RS19015
gene id: 112234:EG359_RS19015
uniprot id: A0A1N7J2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS13610
gene id: 112234:EG359_RS13610
uniprot id: A0A1N7JVS9
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

112234:EG359 RS16555
gene id: 112234:EG359_RS16555
uniprot id: A0A1N7IAD9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS09580
gene id: 112234:EG359_RS09580
uniprot id: A0A1N7I418
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS14405
gene id: 112234:EG359_RS14405
uniprot id: A0A1N7I7B9
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

112234:EG359 RS13780
gene id: 112234:EG359_RS13780
uniprot id: A0A1N7JXM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

112234:EG359 RS12440
gene id: 112234:EG359_RS12440
uniprot id: A0A1N7II54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

112234:EG359 RS16365
gene id: 112234:EG359_RS16365
uniprot id: A0A1N7IA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

112234:EG359 RS08620
gene id: 112234:EG359_RS08620
uniprot id: A0A1N7I302
names: Similarity
messages: Belongs to the barstar family.

112234:EG359 RS08390
gene id: 112234:EG359_RS08390
uniprot id: A0A1N7I2P3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04390
gene id: 112234:EG359_RS04390
uniprot id: A0A1N7HW20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS20960
gene id: 112234:EG359_RS20960
uniprot id: A0A3G6RGQ7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

112234:EG359 RS01525
gene id: 112234:EG359_RS01525
uniprot id: A0A1N7IQ35
names: Similarity
messages: Belongs to the SUI1 family.

112234:EG359 RS10625
gene id: 112234:EG359_RS10625
uniprot id: A0A1N7IG86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

112234:EG359 RS16585
gene id: 112234:EG359_RS16585
uniprot id: A0A1N7IAD7
names: Similarity
messages: Belongs to the Dps family.

112234:EG359 RS10595
gene id: 112234:EG359_RS10595
uniprot id: A0A1N7IG84
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS15130
gene id: 112234:EG359_RS15130
uniprot id: A0A1N7I8D1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

112234:EG359 RS06555
gene id: 112234:EG359_RS06555
uniprot id: A0A1N7HSB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

112234:EG359 RS04745
gene id: 112234:EG359_RS04745
uniprot id: A0A1N7HVG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

112234:EG359 RS16200
gene id: 112234:EG359_RS16200
uniprot id: A0A1N7I9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS14070
gene id: 112234:EG359_RS14070
uniprot id: A0A1N7I6P0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

112234:EG359 RS21955
gene id: 112234:EG359_RS21955
uniprot id: A0A1N7IE88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

112234:EG359 RS04105
gene id: 112234:EG359_RS04105
uniprot id: A0A1N7HWY2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

112234:EG359 RS02105
gene id: 112234:EG359_RS02105
uniprot id: A0A1N7IN71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

112234:EG359 RS01430
gene id: 112234:EG359_RS01430
uniprot id: A0A1N7IQP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

112234:EG359 RS20970
gene id: 112234:EG359_RS20970
uniprot id: A0A1N7ICN8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS04305
gene id: 112234:EG359_RS04305
uniprot id: A0A1N7HWK2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS20685
gene id: 112234:EG359_RS20685
uniprot id: A0A1N7IC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS03365
gene id: 112234:EG359_RS03365
uniprot id: A0A1N7HXL1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

112234:EG359 RS21485
gene id: 112234:EG359_RS21485
uniprot id: A0A1N7IDJ2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

112234:EG359 RS13265
gene id: 112234:EG359_RS13265
uniprot id: A0A1N7JR71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

112234:EG359 RS15280
gene id: 112234:EG359_RS15280
uniprot id: A0A1N7I8M0
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS10915
gene id: 112234:EG359_RS10915
uniprot id: A0A1N7IGI9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15765
gene id: 112234:EG359_RS15765
uniprot id: A0A1N7I9C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

112234:EG359 RS13440
gene id: 112234:EG359_RS13440
uniprot id: A0A1N7JTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

112234:EG359 RS21295
gene id: 112234:EG359_RS21295
uniprot id: A0A1N7ID92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS08740
gene id: 112234:EG359_RS08740
uniprot id: A0A3G6R3S7
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

112234:EG359 RS08100
gene id: 112234:EG359_RS08100
uniprot id: A0A1N7I2C9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

112234:EG359 RS09335
gene id: 112234:EG359_RS09335
uniprot id: A0A1N7I3S1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

112234:EG359 RS02010
gene id: 112234:EG359_RS02010
uniprot id: A0A1N7INB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

112234:EG359 RS12810
gene id: 112234:EG359_RS12810
uniprot id: A0A3G6RL77
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS05415
gene id: 112234:EG359_RS05415
uniprot id: A0A1N7HU80
names: Similarity
messages: Belongs to the barstar family.

112234:EG359 RS18395
gene id: 112234:EG359_RS18395
uniprot id: A0A1N7IZG6
names: Similarity
messages: Belongs to the IMPACT family.

112234:EG359 RS12095
gene id: 112234:EG359_RS12095
uniprot id: A0A3G6RAS9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01330
gene id: 112234:EG359_RS01330
uniprot id: A0A1N7IQR8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

112234:EG359 RS01955
gene id: 112234:EG359_RS01955
uniprot id: A0A1N7INU6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

112234:EG359 RS01225
gene id: 112234:EG359_RS01225
uniprot id: A0A1N7IR51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

112234:EG359 RS16400
gene id: 112234:EG359_RS16400
uniprot id: A0A3G6RGW2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

112234:EG359 RS01570
gene id: 112234:EG359_RS01570
uniprot id: A0A1N7IPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS00225
gene id: 112234:EG359_RS00225
uniprot id: A0A3G6R977
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

112234:EG359 RS00145
gene id: 112234:EG359_RS00145
uniprot id: A0A1N7IEQ8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

112234:EG359 RS14770
gene id: 112234:EG359_RS14770
uniprot id: A0A1N7I7R7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

112234:EG359 RS15300
gene id: 112234:EG359_RS15300
uniprot id: A0A1N7I8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS16535
gene id: 112234:EG359_RS16535
uniprot id: A0A3G6RGY4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

112234:EG359 RS20245
gene id: 112234:EG359_RS20245
uniprot id: A0A1N7KER2
names: Similarity
messages: Belongs to the thioredoxin family.

112234:EG359 RS05225
gene id: 112234:EG359_RS05225
uniprot id: A0A1N7HUJ2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

112234:EG359 RS00760
gene id: 112234:EG359_RS00760
uniprot id: A0A1N7ITI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS18855
gene id: 112234:EG359_RS18855
uniprot id: A0A3G6R964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

112234:EG359 RS21165
gene id: 112234:EG359_RS21165
uniprot id: A0A1N7ID54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

112234:EG359 RS16800
gene id: 112234:EG359_RS16800
uniprot id: A0A1N7IAS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

112234:EG359 RS09365
gene id: 112234:EG359_RS09365
uniprot id: A0A1N7I3W7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

112234:EG359 RS01625
gene id: 112234:EG359_RS01625
uniprot id: A0A1N7IPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

112234:EG359 RS18945
gene id: 112234:EG359_RS18945
uniprot id: A0A1N7J2A8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

112234:EG359 RS12930
gene id: 112234:EG359_RS12930
uniprot id: A0A1N7JME6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

112234:EG359 RS18295
gene id: 112234:EG359_RS18295
uniprot id: A0A1N7IZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS13775
gene id: 112234:EG359_RS13775
uniprot id: A0A1N7JXK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

112234:EG359 RS02535
gene id: 112234:EG359_RS02535
uniprot id: A0A1N7IL42
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

112234:EG359 RS01670
gene id: 112234:EG359_RS01670
uniprot id: A0A1N7IPM9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

112234:EG359 RS17620
gene id: 112234:EG359_RS17620
uniprot id: A0A1N7K7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

112234:EG359 RS16575
gene id: 112234:EG359_RS16575
uniprot id: A0A1N7IAA7
names: Similarity
messages: Belongs to the YciI family.

112234:EG359 RS12660
gene id: 112234:EG359_RS12660
uniprot id: A0A1N7IIJ6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

112234:EG359 RS21700
gene id: 112234:EG359_RS21700
uniprot id: A0A1N7IDV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS15375
gene id: 112234:EG359_RS15375
uniprot id: A0A1N7I8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

112234:EG359 RS00340
gene id: 112234:EG359_RS00340
uniprot id: A0A3G6RDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

112234:EG359 RS10430
gene id: 112234:EG359_RS10430
uniprot id: A0A1N7IG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

112234:EG359 RS21690
gene id: 112234:EG359_RS21690
uniprot id: A0A1N7IE24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

112234:EG359 RS22045
gene id: 112234:EG359_RS22045
uniprot id: A0A1N7IEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

112234:EG359 RS21310
gene id: 112234:EG359_RS21310
uniprot id: A0A3G6RC84
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16615
gene id: 112234:EG359_RS16615
uniprot id: A0A1N7IAC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

112234:EG359 RS15720
gene id: 112234:EG359_RS15720
uniprot id: A0A1N7I9J3
names: Similarity
messages: Belongs to the peptidase S9A family.

112234:EG359 RS01210
gene id: 112234:EG359_RS01210
uniprot id: A0A1N7IR69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09145
gene id: 112234:EG359_RS09145
uniprot id: A0A1N7I3K6
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS13455
gene id: 112234:EG359_RS13455
uniprot id: A0A1N7JTU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS00430
gene id: 112234:EG359_RS00430
uniprot id: A0A1N7IF88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

112234:EG359 RS16720
gene id: 112234:EG359_RS16720
uniprot id: A0A1N7IAG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

112234:EG359 RS22090
gene id: 112234:EG359_RS22090
uniprot id: A0A1N7IEG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

112234:EG359 RS19485
gene id: 112234:EG359_RS19485
uniprot id: A0A1N7J4K4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

112234:EG359 RS22075
gene id: 112234:EG359_RS22075
uniprot id: A0A1N7IEF9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

112234:EG359 RS16455
gene id: 112234:EG359_RS16455
uniprot id: A0A3G6RB09
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

112234:EG359 RS03945
gene id: 112234:EG359_RS03945
uniprot id: A0A1N7HX11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS00295
gene id: 112234:EG359_RS00295
uniprot id: A0A1N7IEY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

112234:EG359 RS21250
gene id: 112234:EG359_RS21250
uniprot id: A0A1N7ID72
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

112234:EG359 RS13400
gene id: 112234:EG359_RS13400
uniprot id: A0A1N7JTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

112234:EG359 RS08275
gene id: 112234:EG359_RS08275
uniprot id: A0A1N7JH50
names: Similarity
messages: Belongs to the aspartokinase family.

112234:EG359 RS09515
gene id: 112234:EG359_RS09515
uniprot id: A0A1N7I429
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

112234:EG359 RS02805
gene id: 112234:EG359_RS02805
uniprot id: A0A1N7HYH1
names: Similarity
messages: Belongs to the DinB family.

112234:EG359 RS20190
gene id: 112234:EG359_RS20190
uniprot id: A0A1N7KDZ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

112234:EG359 RS00235
gene id: 112234:EG359_RS00235
uniprot id: A0A3G6RGL1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

112234:EG359 RS03240
gene id: 112234:EG359_RS03240
uniprot id: A0A1N7HXM7
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS14895
gene id: 112234:EG359_RS14895
uniprot id: A0A3G6R710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

112234:EG359 RS18150
gene id: 112234:EG359_RS18150
uniprot id: A0A1N7IYF9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

112234:EG359 RS00460
gene id: 112234:EG359_RS00460
uniprot id: A0A1N7IF52
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

112234:EG359 RS01795
gene id: 112234:EG359_RS01795
uniprot id: A0A1N7IP74
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09770
gene id: 112234:EG359_RS09770
uniprot id: A0A1N7I4F2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS08300
gene id: 112234:EG359_RS08300
uniprot id: A0A1N7JH47
names: Similarity
messages: Belongs to the terpene synthase family.

112234:EG359 RS20905
gene id: 112234:EG359_RS20905
uniprot id: A0A1N7ICT2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

112234:EG359 RS12445
gene id: 112234:EG359_RS12445
uniprot id: A0A1N7II24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

112234:EG359 RS16500
gene id: 112234:EG359_RS16500
uniprot id: A0A3G6REJ7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

112234:EG359 RS18330
gene id: 112234:EG359_RS18330
uniprot id: A0A1N7IZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS02190
gene id: 112234:EG359_RS02190
uniprot id: A0A1N7IMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS19480
gene id: 112234:EG359_RS19480
uniprot id: A0A1N7J4X9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

112234:EG359 RS10460
gene id: 112234:EG359_RS10460
uniprot id: A0A1N7IG16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

112234:EG359 RS07415
gene id: 112234:EG359_RS07415
uniprot id: A0A1N7I1K7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS09250
gene id: 112234:EG359_RS09250
uniprot id: A0A1N7I3N2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

112234:EG359 RS08770
gene id: 112234:EG359_RS08770
uniprot id: A0A1N7I398
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

112234:EG359 RS03735
gene id: 112234:EG359_RS03735
uniprot id: A0A1N7HXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

112234:EG359 RS16245
gene id: 112234:EG359_RS16245
uniprot id: A0A1N7IA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS15750
gene id: 112234:EG359_RS15750
uniprot id: A0A1N7I9K3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS19325
gene id: 112234:EG359_RS19325
uniprot id: A0A1N7J439
names: Similarity
messages: Belongs to the YjdM family.

112234:EG359 RS07725
gene id: 112234:EG359_RS07725
uniprot id: A0A1N7I1Z2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

112234:EG359 RS02760
gene id: 112234:EG359_RS02760
uniprot id: A0A1N7HYJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS16170
gene id: 112234:EG359_RS16170
uniprot id: A0A1N7IA22
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

112234:EG359 RS21075
gene id: 112234:EG359_RS21075
uniprot id: A0A1N7ICX1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

112234:EG359 RS06305
gene id: 112234:EG359_RS06305
uniprot id: A0A1N7HSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS00075
gene id: 112234:EG359_RS00075
uniprot id: A0A1N7IEM3
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS16820
gene id: 112234:EG359_RS16820
uniprot id: A0A1N7IAT4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

112234:EG359 RS16340
gene id: 112234:EG359_RS16340
uniprot id: A0A1N7IAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

112234:EG359 RS12675
gene id: 112234:EG359_RS12675
uniprot id: A0A1N7IIH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS16015
gene id: 112234:EG359_RS16015
uniprot id: A0A1N7I9S1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

112234:EG359 RS01365
gene id: 112234:EG359_RS01365
uniprot id: A0A1N7IQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

112234:EG359 RS09130
gene id: 112234:EG359_RS09130
uniprot id: A0A1N7I3J5
names: Similarity
messages: Belongs to the DinB family.

112234:EG359 RS14010
gene id: 112234:EG359_RS14010
uniprot id: A0A1N7I6K4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

112234:EG359 RS13185
gene id: 112234:EG359_RS13185
uniprot id: A0A1N7JQJ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

112234:EG359 RS03395
gene id: 112234:EG359_RS03395
uniprot id: A0A1N7HXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS09275
gene id: 112234:EG359_RS09275
uniprot id: A0A1N7I3L4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

112234:EG359 RS00685
gene id: 112234:EG359_RS00685
uniprot id: A0A1N7ITG5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS15435
gene id: 112234:EG359_RS15435
uniprot id: A0A1N7I929
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

112234:EG359 RS00575
gene id: 112234:EG359_RS00575
uniprot id: A0A1N7IFF2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

112234:EG359 RS11980
gene id: 112234:EG359_RS11980
uniprot id: A0A1N7IHH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

112234:EG359 RS14190
gene id: 112234:EG359_RS14190
uniprot id: A0A1N7I6X2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

112234:EG359 RS13415
gene id: 112234:EG359_RS13415
uniprot id: A0A1N7JTA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

112234:EG359 RS16215
gene id: 112234:EG359_RS16215
uniprot id: A0A1N7IA41
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

112234:EG359 RS21105
gene id: 112234:EG359_RS21105
uniprot id: A0A1N7ID39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

112234:EG359 RS07710
gene id: 112234:EG359_RS07710
uniprot id: A0A1N7JEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

112234:EG359 RS03160
gene id: 112234:EG359_RS03160
uniprot id: A0A1N7HXV0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS03805
gene id: 112234:EG359_RS03805
uniprot id: A0A1N7HX35
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS08665
gene id: 112234:EG359_RS08665
uniprot id: A0A1N7I384
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

112234:EG359 RS16705
gene id: 112234:EG359_RS16705
uniprot id: A0A1N7IAJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

112234:EG359 RS04890
gene id: 112234:EG359_RS04890
uniprot id: A0A3G6R1T6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS09560
gene id: 112234:EG359_RS09560
uniprot id: A0A1N7I457
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS04800
gene id: 112234:EG359_RS04800
uniprot id: A0A1N7HVM8
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16930
gene id: 112234:EG359_RS16930
uniprot id: A0A1N7IAP2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

112234:EG359 RS17920
gene id: 112234:EG359_RS17920
uniprot id: A0A1N7K3G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

112234:EG359 RS13055
gene id: 112234:EG359_RS13055
uniprot id: A0A1N7JNL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

112234:EG359 RS14540
gene id: 112234:EG359_RS14540
uniprot id: A0A1N7I7R3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

112234:EG359 RS00190
gene id: 112234:EG359_RS00190
uniprot id: A0A1N7IES4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

112234:EG359 RS16380
gene id: 112234:EG359_RS16380
uniprot id: A0A1N7IA55
names: Similarity
messages: Belongs to the SCO1/2 family.

112234:EG359 RS09270
gene id: 112234:EG359_RS09270
uniprot id: A0A1N7I3N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

112234:EG359 RS15235
gene id: 112234:EG359_RS15235
uniprot id: A0A1N7I8Q3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01685
gene id: 112234:EG359_RS01685
uniprot id: A0A1N7IPK5
names: Similarity
messages: Belongs to the UPF0758 family.

112234:EG359 RS02495
gene id: 112234:EG359_RS02495
uniprot id: A0A1N7ILH5
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS01150
gene id: 112234:EG359_RS01150
uniprot id: A0A1N7IRQ5
names: Similarity
messages: Belongs to the DEAD box helicase family.

112234:EG359 RS00065
gene id: 112234:EG359_RS00065
uniprot id: A0A3G6R493
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

112234:EG359 RS04620
gene id: 112234:EG359_RS04620
uniprot id: A0A1N7HVP4
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

112234:EG359 RS10745
gene id: 112234:EG359_RS10745
uniprot id: A0A1N7IGG9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

112234:EG359 RS15425
gene id: 112234:EG359_RS15425
uniprot id: A0A1N7I8U6
names: Similarity
messages: Belongs to the MreC family.

112234:EG359 RS05835
gene id: 112234:EG359_RS05835
uniprot id: A0A1N7HTG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS22265
gene id: 112234:EG359_RS22265
uniprot id: A0A1N7KFU7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

112234:EG359 RS21865
gene id: 112234:EG359_RS21865
uniprot id: A0A3G6RAL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

112234:EG359 RS12335
gene id: 112234:EG359_RS12335
uniprot id: A0A1N7IHX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

112234:EG359 RS21655
gene id: 112234:EG359_RS21655
uniprot id: A0A1N7IDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

112234:EG359 RS20495
gene id: 112234:EG359_RS20495
uniprot id: A0A1N7IBX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS02160
gene id: 112234:EG359_RS02160
uniprot id: A0A1N7IMN4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

112234:EG359 RS07900
gene id: 112234:EG359_RS07900
uniprot id: A0A1N7JFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

112234:EG359 RS14565
gene id: 112234:EG359_RS14565
uniprot id: A0A1N7I7L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

112234:EG359 RS16700
gene id: 112234:EG359_RS16700
uniprot id: A0A1N7IAF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

112234:EG359 RS15090
gene id: 112234:EG359_RS15090
uniprot id: A0A1N7I8B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

112234:EG359 RS19415
gene id: 112234:EG359_RS19415
uniprot id: A0A1N7J4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS21150
gene id: 112234:EG359_RS21150
uniprot id: A0A1N7ID41
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

112234:EG359 RS15915
gene id: 112234:EG359_RS15915
uniprot id: A0A1N7I9P5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

112234:EG359 RS01910
gene id: 112234:EG359_RS01910
uniprot id: A0A1N7INU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS04530
gene id: 112234:EG359_RS04530
uniprot id: A0A1N7HW30
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

112234:EG359 RS10420
gene id: 112234:EG359_RS10420
uniprot id: A0A1N7IG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

112234:EG359 RS12670
gene id: 112234:EG359_RS12670
uniprot id: A0A1N7IIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16945
gene id: 112234:EG359_RS16945
uniprot id: A0A1N7IAS5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

112234:EG359 RS21715
gene id: 112234:EG359_RS21715
uniprot id: A0A1N7IDW7
names: Similarity
messages: Belongs to the peptidase M1 family.

112234:EG359 RS11450
gene id: 112234:EG359_RS11450
uniprot id: A0A1N7IH11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

112234:EG359 RS03330
gene id: 112234:EG359_RS03330
uniprot id: A0A1N7HXT6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS21990
gene id: 112234:EG359_RS21990
uniprot id: A0A1N7IEC4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

112234:EG359 RS13460
gene id: 112234:EG359_RS13460
uniprot id: A0A1N7JTX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

112234:EG359 RS00130
gene id: 112234:EG359_RS00130
uniprot id: A0A1N7IEQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS10680
gene id: 112234:EG359_RS10680
uniprot id: A0A1N7IGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS21595
gene id: 112234:EG359_RS21595
uniprot id: A0A1N7IDR1
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS19395
gene id: 112234:EG359_RS19395
uniprot id: A0A1N7J484
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

112234:EG359 RS18100
gene id: 112234:EG359_RS18100
uniprot id: A0A1N7IYL2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

112234:EG359 RS17485
gene id: 112234:EG359_RS17485
uniprot id: A0A1N7K913
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

112234:EG359 RS07835
gene id: 112234:EG359_RS07835
uniprot id: A0A1N7I1Z9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS15010
gene id: 112234:EG359_RS15010
uniprot id: A0A1N7I862
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

112234:EG359 RS01240
gene id: 112234:EG359_RS01240
uniprot id: A0A1N7IR40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

112234:EG359 RS04020
gene id: 112234:EG359_RS04020
uniprot id: A0A1N7HX40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

112234:EG359 RS11585
gene id: 112234:EG359_RS11585
uniprot id: A0A1N7IH83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

112234:EG359 RS08255
gene id: 112234:EG359_RS08255
uniprot id: A0A1N7JHE8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

112234:EG359 RS11810
gene id: 112234:EG359_RS11810
uniprot id: A0A1N7IHE7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

112234:EG359 RS12240
gene id: 112234:EG359_RS12240
uniprot id: A0A3G6REQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

112234:EG359 RS15395
gene id: 112234:EG359_RS15395
uniprot id: A0A1N7I8S1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

112234:EG359 RS02015
gene id: 112234:EG359_RS02015
uniprot id: A0A1N7IN88
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

112234:EG359 RS09165
gene id: 112234:EG359_RS09165
uniprot id: A0A1N7I3M7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

112234:EG359 RS01400
gene id: 112234:EG359_RS01400
uniprot id: A0A1N7IQK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

112234:EG359 RS15645
gene id: 112234:EG359_RS15645
uniprot id: A0A1N7I9C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

112234:EG359 RS17860
gene id: 112234:EG359_RS17860
uniprot id: A0A1N7K4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

112234:EG359 RS21160
gene id: 112234:EG359_RS21160
uniprot id: A0A1N7ID24
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

112234:EG359 RS21460
gene id: 112234:EG359_RS21460
uniprot id: A0A1N7IDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

112234:EG359 RS13855
gene id: 112234:EG359_RS13855
uniprot id: A0A1N7JYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

112234:EG359 RS15890
gene id: 112234:EG359_RS15890
uniprot id: A0A1N7I9N5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

112234:EG359 RS09990
gene id: 112234:EG359_RS09990
uniprot id: A0A1N7I506
names: Similarity
messages: Belongs to the Skp family.

112234:EG359 RS05090
gene id: 112234:EG359_RS05090
uniprot id: A0A1N7HUS7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

112234:EG359 RS07140
gene id: 112234:EG359_RS07140
uniprot id: A0A1N7I0Z0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

112234:EG359 RS15760
gene id: 112234:EG359_RS15760
uniprot id: A0A1N7I9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

112234:EG359 RS04295
gene id: 112234:EG359_RS04295
uniprot id: A0A1N7HWC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS17495
gene id: 112234:EG359_RS17495
uniprot id: A0A1N7K8X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

112234:EG359 RS16750
gene id: 112234:EG359_RS16750
uniprot id: A0A1N7IAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

112234:EG359 RS15510
gene id: 112234:EG359_RS15510
uniprot id: A0A1N7I905
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

112234:EG359 RS10910
gene id: 112234:EG359_RS10910
uniprot id: A0A1N7IGQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

112234:EG359 RS22080
gene id: 112234:EG359_RS22080
uniprot id: A0A1N7IEG4
names: Similarity
messages: Belongs to the ArsC family.

112234:EG359 RS19340
gene id: 112234:EG359_RS19340
uniprot id: A0A1N7J405
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

112234:EG359 RS10975
gene id: 112234:EG359_RS10975
uniprot id: A0A1N7IGQ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS12510
gene id: 112234:EG359_RS12510
uniprot id: A0A1N7II62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

112234:EG359 RS16755
gene id: 112234:EG359_RS16755
uniprot id: A0A1N7IAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

112234:EG359 RS15420
gene id: 112234:EG359_RS15420
uniprot id: A0A1N7I8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

112234:EG359 RS04510
gene id: 112234:EG359_RS04510
uniprot id: A0A1N7HVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

112234:EG359 RS00905
gene id: 112234:EG359_RS00905
uniprot id: A0A1N7ISP7
names: Similarity
messages: Belongs to the peptidase M1 family.

112234:EG359 RS02970
gene id: 112234:EG359_RS02970
uniprot id: A0A1N7HY43
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

112234:EG359 RS14740
gene id: 112234:EG359_RS14740
uniprot id: A0A1N7I7Q7
names: Similarity
messages: Belongs to the SufE family.

112234:EG359 RS13350
gene id: 112234:EG359_RS13350
uniprot id: A0A1N7JSE9
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS05580
gene id: 112234:EG359_RS05580
uniprot id: A0A1N7HTW5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

112234:EG359 RS07730
gene id: 112234:EG359_RS07730
uniprot id: A0A1N7I220
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

112234:EG359 RS22135
gene id: 112234:EG359_RS22135
uniprot id: A0A1N7IEJ4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

112234:EG359 RS15225
gene id: 112234:EG359_RS15225
uniprot id: A0A1N7I8I7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

112234:EG359 RS12915
gene id: 112234:EG359_RS12915
uniprot id: A0A1N7JMA2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

112234:EG359 RS04005
gene id: 112234:EG359_RS04005
uniprot id: A0A1N7HWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

112234:EG359 RS21840
gene id: 112234:EG359_RS21840
uniprot id: A0A1N7IE27
names: Similarity
messages: Belongs to the nitroreductase family.

112234:EG359 RS05160
gene id: 112234:EG359_RS05160
uniprot id: A0A1N7HUR2
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS00055
gene id: 112234:EG359_RS00055
uniprot id: A0A1N7IEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS20880
gene id: 112234:EG359_RS20880
uniprot id: A0A1N7ICR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

112234:EG359 RS16840
gene id: 112234:EG359_RS16840
uniprot id: A0A1N7IAR1
names: Similarity
messages: Belongs to the citrate synthase family.

112234:EG359 RS19385
gene id: 112234:EG359_RS19385
uniprot id: A0A1N7J4B3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

112234:EG359 RS18915
gene id: 112234:EG359_RS18915
uniprot id: A0A1N7J278
names: Similarity
messages: Belongs to the HSP15 family.

112234:EG359 RS03870
gene id: 112234:EG359_RS03870
uniprot id: A0A1N7HX33
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS20025
gene id: 112234:EG359_RS20025
uniprot id: A0A1N7KC38
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

112234:EG359 RS05220
gene id: 112234:EG359_RS05220
uniprot id: A0A1N7HUU3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

112234:EG359 RS19020
gene id: 112234:EG359_RS19020
uniprot id: A0A1N7J2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

112234:EG359 RS03825
gene id: 112234:EG359_RS03825
uniprot id: A0A1N7HX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS00160
gene id: 112234:EG359_RS00160
uniprot id: A0A1N7IER4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

112234:EG359 RS18640
gene id: 112234:EG359_RS18640
uniprot id: A0A1N7J0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

112234:EG359 RS14465
gene id: 112234:EG359_RS14465
uniprot id: A0A1N7I7L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

112234:EG359 RS21890
gene id: 112234:EG359_RS21890
uniprot id: A0A1N7IE60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS12685
gene id: 112234:EG359_RS12685
uniprot id: A0A1N7IIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS09280
gene id: 112234:EG359_RS09280
uniprot id: A0A1N7I3Q6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

112234:EG359 RS12315
gene id: 112234:EG359_RS12315
uniprot id: A0A1N7IHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

112234:EG359 RS17380
gene id: 112234:EG359_RS17380
uniprot id: A0A1N7IB78
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

112234:EG359 RS10895
gene id: 112234:EG359_RS10895
uniprot id: A0A1N7IGK2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

112234:EG359 RS16620
gene id: 112234:EG359_RS16620
uniprot id: A0A3G6RC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS05440
gene id: 112234:EG359_RS05440
uniprot id: A0A1N7HU82
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

112234:EG359 RS12035
gene id: 112234:EG359_RS12035
uniprot id: A0A1N7IHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

112234:EG359 RS10535
gene id: 112234:EG359_RS10535
uniprot id: A0A1N7IG46
names: Similarity
messages: Belongs to the peptidase S49 family.

112234:EG359 RS21765
gene id: 112234:EG359_RS21765
uniprot id: A0A1N7IDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS18170
gene id: 112234:EG359_RS18170
uniprot id: A0A3G6RJX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

112234:EG359 RS04885
gene id: 112234:EG359_RS04885
uniprot id: A0A1N7HV58
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

112234:EG359 RS03910
gene id: 112234:EG359_RS03910
uniprot id: A0A1N7HXB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

112234:EG359 RS06625
gene id: 112234:EG359_RS06625
uniprot id: A0A1N7HS17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS19495
gene id: 112234:EG359_RS19495
uniprot id: A0A1N7J4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS04100
gene id: 112234:EG359_RS04100
uniprot id: A0A1N7HWQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

112234:EG359 RS10565
gene id: 112234:EG359_RS10565
uniprot id: A0A1N7IGK0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

112234:EG359 RS10690
gene id: 112234:EG359_RS10690
uniprot id: A0A1N7IGI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

112234:EG359 RS09775
gene id: 112234:EG359_RS09775
uniprot id: A0A1N7I4A6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

112234:EG359 RS01245
gene id: 112234:EG359_RS01245
uniprot id: A0A1N7IR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

112234:EG359 RS05310
gene id: 112234:EG359_RS05310
uniprot id: A0A1N7HUP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS18430
gene id: 112234:EG359_RS18430
uniprot id: A0A1N7IZU0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

112234:EG359 RS18255
gene id: 112234:EG359_RS18255
uniprot id: A0A1N7IYU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

112234:EG359 RS14835
gene id: 112234:EG359_RS14835
uniprot id: A0A1N7I7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

112234:EG359 RS03150
gene id: 112234:EG359_RS03150
uniprot id: A0A1N7HXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS20590
gene id: 112234:EG359_RS20590
uniprot id: A0A1N7IC34
names: Similarity
messages: Belongs to the peptidase M13 family.

112234:EG359 RS09840
gene id: 112234:EG359_RS09840
uniprot id: A0A1N7I4J4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

112234:EG359 RS13550
gene id: 112234:EG359_RS13550
uniprot id: A0A1N7JV47
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

112234:EG359 RS21480
gene id: 112234:EG359_RS21480
uniprot id: A0A1N7IDH3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

112234:EG359 RS17035
gene id: 112234:EG359_RS17035
uniprot id: A0A1N7IAV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

112234:EG359 RS13410
gene id: 112234:EG359_RS13410
uniprot id: A0A1N7JT81
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS11335
gene id: 112234:EG359_RS11335
uniprot id: A0A3G6R8D1
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

112234:EG359 RS19805
gene id: 112234:EG359_RS19805
uniprot id: A0A1N7J616
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

112234:EG359 RS15150
gene id: 112234:EG359_RS15150
uniprot id: A0A1N7I8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

112234:EG359 RS18225
gene id: 112234:EG359_RS18225
uniprot id: A0A1N7IYP6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

112234:EG359 RS22110
gene id: 112234:EG359_RS22110
uniprot id: A0A1N7IEI1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

112234:EG359 RS08400
gene id: 112234:EG359_RS08400
uniprot id: A0A1N7I2Q6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

112234:EG359 RS11010
gene id: 112234:EG359_RS11010
uniprot id: A0A1N7IGU5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

112234:EG359 RS18715
gene id: 112234:EG359_RS18715
uniprot id: A0A1N7J160
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

112234:EG359 RS14275
gene id: 112234:EG359_RS14275
uniprot id: A0A1N7I762
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

112234:EG359 RS16230
gene id: 112234:EG359_RS16230
uniprot id: A0A1N7IA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

112234:EG359 RS08530
gene id: 112234:EG359_RS08530
uniprot id: A0A1N7I2Z7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

112234:EG359 RS19585
gene id: 112234:EG359_RS19585
uniprot id: A0A1N7J516
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

112234:EG359 RS03555
gene id: 112234:EG359_RS03555
uniprot id: A0A1N7HXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

112234:EG359 RS19530
gene id: 112234:EG359_RS19530
uniprot id: A0A1N7J529
names: Similarity
messages: Belongs to the ABC transporter superfamily.

112234:EG359 RS19945
gene id: 112234:EG359_RS19945
uniprot id: A0A1N7KIT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

112234:EG359 RS04130
gene id: 112234:EG359_RS04130
uniprot id: A0A1N7HWT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

112234:EG359 RS15860
gene id: 112234:EG359_RS15860
uniprot id: A0A3G6RAP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

112234:EG359 RS16825
gene id: 112234:EG359_RS16825
uniprot id: A0A1N7IAX6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

112234:EG359 RS06495
gene id: 112234:EG359_RS06495
uniprot id: A0A1N7HSM8
names: Similarity
messages: Belongs to the Dps family.

112234:EG359 RS02710
gene id: 112234:EG359_RS02710
uniprot id: A0A1N7HZ14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

112234:EG359 RS04160
gene id: 112234:EG359_RS04160
uniprot id: A0A1N7HWK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

112234:EG359 RS17025
gene id: 112234:EG359_RS17025
uniprot id: A0A1N7IAU5
names: Cofactor
messages: Binds 1 FAD per subunit.

112234:EG359 RS00245
gene id: 112234:EG359_RS00245
uniprot id: A0A1N7IEV5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

112234:EG359 RS21615
gene id: 112234:EG359_RS21615
uniprot id: A0A1N7IDT0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

112234:EG359 RS21630
gene id: 112234:EG359_RS21630
uniprot id: A0A1N7IDS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

112234:EG359 RS06405
gene id: 112234:EG359_RS06405
uniprot id: A0A1N7HS99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

112234:EG359 RS18400
gene id: 112234:EG359_RS18400
uniprot id: A0A1N7IZI0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

112234:EG359 RS15075
gene id: 112234:EG359_RS15075
uniprot id: A0A1N7I890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

112234:EG359 RS06445
gene id: 112234:EG359_RS06445
uniprot id: A0A1N7HSE1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

112234:EG359 RS18125
gene id: 112234:EG359_RS18125
uniprot id: A0A1N7IYD1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

112234:EG359 RS09415
gene id: 112234:EG359_RS09415
uniprot id: A0A1N7I3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS20710
gene id: 112234:EG359_RS20710
uniprot id: A0A1N7ICA1
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS02090
gene id: 112234:EG359_RS02090
uniprot id: A0A1N7IN00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

112234:EG359 RS02555
gene id: 112234:EG359_RS02555
uniprot id: A0A1N7IL01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

112234:EG359 RS12090
gene id: 112234:EG359_RS12090
uniprot id: A0A1N7IHS1
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS16605
gene id: 112234:EG359_RS16605
uniprot id: A0A1N7IAE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

112234:EG359 RS01380
gene id: 112234:EG359_RS01380
uniprot id: A0A1N7IQV6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

112234:EG359 RS01540
gene id: 112234:EG359_RS01540
uniprot id: A0A1N7IQ33
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

112234:EG359 RS13975
gene id: 112234:EG359_RS13975
uniprot id: A0A1N7I6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

112234:EG359 RS03130
gene id: 112234:EG359_RS03130
uniprot id: A0A1N7HY71
names: Similarity
messages: Belongs to the IucA/IucC family.

112234:EG359 RS00645
gene id: 112234:EG359_RS00645
uniprot id: A0A1N7ITM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS16610
gene id: 112234:EG359_RS16610
uniprot id: A0A1N7IAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

112234:EG359 RS08700
gene id: 112234:EG359_RS08700
uniprot id: A0A1N7I3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS05370
gene id: 112234:EG359_RS05370
uniprot id: A0A1N7HUL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

112234:EG359 RS03515
gene id: 112234:EG359_RS03515
uniprot id: A0A1N7HXG3
names: Similarity
messages: Belongs to the AHA1 family.

112234:EG359 RS10925
gene id: 112234:EG359_RS10925
uniprot id: A0A1N7IGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

112234:EG359 RS16250
gene id: 112234:EG359_RS16250
uniprot id: A0A1N7I9Z2
names: Similarity
messages: Belongs to the SusD family.

112234:EG359 RS10855
gene id: 112234:EG359_RS10855
uniprot id: A0A1N7IGI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

112234:EG359 RS06370
gene id: 112234:EG359_RS06370
uniprot id: A0A1N7HSS2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS06580
gene id: 112234:EG359_RS06580
uniprot id: A0A3G6R3D5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

112234:EG359 RS13585
gene id: 112234:EG359_RS13585
uniprot id: A0A1N7JVI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

112234:EG359 RS18460
gene id: 112234:EG359_RS18460
uniprot id: A0A1N7IZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

112234:EG359 RS08365
gene id: 112234:EG359_RS08365
uniprot id: A0A1N7I2M6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS02750
gene id: 112234:EG359_RS02750
uniprot id: A0A1N7HYP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

112234:EG359 RS09380
gene id: 112234:EG359_RS09380
uniprot id: A0A1N7I3V2
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS21785
gene id: 112234:EG359_RS21785
uniprot id: A0A1N7IDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

112234:EG359 RS03790
gene id: 112234:EG359_RS03790
uniprot id: A0A1N7HX73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

112234:EG359 RS20615
gene id: 112234:EG359_RS20615
uniprot id: A0A1N7IC30
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

112234:EG359 RS06455
gene id: 112234:EG359_RS06455
uniprot id: A0A1N7HSP2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

112234:EG359 RS11345
gene id: 112234:EG359_RS11345
uniprot id: A0A1N7IH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

112234:EG359 RS18835
gene id: 112234:EG359_RS18835
uniprot id: A0A1N7J1L2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

112234:EG359 RS02725
gene id: 112234:EG359_RS02725
uniprot id: A0A1N7HZ04
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

112234:EG359 RS05390
gene id: 112234:EG359_RS05390
uniprot id: A0A1N7HUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

112234:EG359 RS18375
gene id: 112234:EG359_RS18375
uniprot id: A0A1N7IZS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

112234:EG359 RS05290
gene id: 112234:EG359_RS05290
uniprot id: A0A1N7HUD7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

112234:EG359 RS01925
gene id: 112234:EG359_RS01925
uniprot id: A0A1N7INN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

112234:EG359 RS03255
gene id: 112234:EG359_RS03255
uniprot id: A0A1N7HXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS10575
gene id: 112234:EG359_RS10575
uniprot id: A0A1N7IG75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

112234:EG359 RS16925
gene id: 112234:EG359_RS16925
uniprot id: A0A1N7IAS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

112234:EG359 RS13580
gene id: 112234:EG359_RS13580
uniprot id: A0A1N7JVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

112234:EG359 RS07770
gene id: 112234:EG359_RS07770
uniprot id: A0A1N7JFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

112234:EG359 RS18960
gene id: 112234:EG359_RS18960
uniprot id: A0A1N7J205
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

112234:EG359 RS08435
gene id: 112234:EG359_RS08435
uniprot id: A0A1N7I2R2
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

112234:EG359 RS12595
gene id: 112234:EG359_RS12595
uniprot id: A0A1N7IIF7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

112234:EG359 RS01635
gene id: 112234:EG359_RS01635
uniprot id: A0A1N7IPT8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

112234:EG359 RS16030
gene id: 112234:EG359_RS16030
uniprot id: A0A1N7I9J4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

112234:EG359 RS10495
gene id: 112234:EG359_RS10495
uniprot id: A0A1N7IG36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

112234:EG359 RS08690
gene id: 112234:EG359_RS08690
uniprot id: A0A1N7I350
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

112234:EG359 RS07815
gene id: 112234:EG359_RS07815
uniprot id: A0A1N7JFD9
names: Similarity
messages: Belongs to the peptidase S33 family.

112234:EG359 RS11440
gene id: 112234:EG359_RS11440
uniprot id: A0A1N7IHG3
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS21275
gene id: 112234:EG359_RS21275
uniprot id: A0A1N7ID74
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

112234:EG359 RS03985
gene id: 112234:EG359_RS03985
uniprot id: A0A1N7HWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

112234:EG359 RS16765
gene id: 112234:EG359_RS16765
uniprot id: A0A1N7IAM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

112234:EG359 RS01560
gene id: 112234:EG359_RS01560
uniprot id: A0A1N7IQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

112234:EG359 RS02930
gene id: 112234:EG359_RS02930
uniprot id: A0A1N7HYC2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

112234:EG359 RS12310
gene id: 112234:EG359_RS12310
uniprot id: A0A1N7IHW6
names: Subcellular Location Annotation
messages: Membrane

112234:EG359 RS13155
gene id: 112234:EG359_RS13155
uniprot id: A0A1N7JPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

112234:EG359 RS18060
gene id: 112234:EG359_RS18060
uniprot id: A0A1N7IYD7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

112234:EG359 RS12185
gene id: 112234:EG359_RS12185
uniprot id: A0A1N7IHM0
names: Subcellular Location Annotation
messages: Nucleus