1121451:DESAM RS00925
gene id: 1121451:DESAM_RS00925
uniprot id: L0R676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121451:DESAM RS13310
gene id: 1121451:DESAM_RS13310
uniprot id: L0RDM3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1121451:DESAM RS09280
gene id: 1121451:DESAM_RS09280
uniprot id: L0RB36
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1121451:DESAM RS01935
gene id: 1121451:DESAM_RS01935
uniprot id: L0R6U1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121451:DESAM RS14955
gene id: 1121451:DESAM_RS14955
uniprot id: L0RHX5
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS11620
gene id: 1121451:DESAM_RS11620
uniprot id: L0RE62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1121451:DESAM RS14050
gene id: 1121451:DESAM_RS14050
uniprot id: L0RE17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS02570
gene id: 1121451:DESAM_RS02570
uniprot id: L0R8K9
names: Similarity
messages: Belongs to the arginase family.

1121451:DESAM RS10485
gene id: 1121451:DESAM_RS10485
uniprot id: L0RBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1121451:DESAM RS13300
gene id: 1121451:DESAM_RS13300
uniprot id: L0RF60
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1121451:DESAM RS04785
gene id: 1121451:DESAM_RS04785
uniprot id: L0R8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121451:DESAM RS00690
gene id: 1121451:DESAM_RS00690
uniprot id: L0R7E9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00645
gene id: 1121451:DESAM_RS00645
uniprot id: L0R7D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS08680
gene id: 1121451:DESAM_RS08680
uniprot id: L0RCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1121451:DESAM RS00250
gene id: 1121451:DESAM_RS00250
uniprot id: L0R751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1121451:DESAM RS05480
gene id: 1121451:DESAM_RS05480
uniprot id: L0R8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1121451:DESAM RS05170
gene id: 1121451:DESAM_RS05170
uniprot id: L0R8N5
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS10180
gene id: 1121451:DESAM_RS10180
uniprot id: L0RBL5
names: Similarity
messages: Belongs to the FeoA family.

1121451:DESAM RS02355
gene id: 1121451:DESAM_RS02355
uniprot id: L0R8K8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121451:DESAM RS00475
gene id: 1121451:DESAM_RS00475
uniprot id: L0R936
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00135
gene id: 1121451:DESAM_RS00135
uniprot id: L0R726
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1121451:DESAM RS01595
gene id: 1121451:DESAM_RS01595
uniprot id: L0R6L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS05110
gene id: 1121451:DESAM_RS05110
uniprot id: L0RA64
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1121451:DESAM RS14935
gene id: 1121451:DESAM_RS14935
uniprot id: L0RG31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1121451:DESAM RS16450
gene id: 1121451:DESAM_RS16450
uniprot id: L0RGZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS02425
gene id: 1121451:DESAM_RS02425
uniprot id: L0RAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1121451:DESAM RS06265
gene id: 1121451:DESAM_RS06265
uniprot id: L0RAV9
names: Similarity
messages: Belongs to the histone deacetylase family.

1121451:DESAM RS00580
gene id: 1121451:DESAM_RS00580
uniprot id: L0R7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1121451:DESAM RS15160
gene id: 1121451:DESAM_RS15160
uniprot id: L0REP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1121451:DESAM RS13250
gene id: 1121451:DESAM_RS13250
uniprot id: L0RF53
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS11635
gene id: 1121451:DESAM_RS11635
uniprot id: L0RG17
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1121451:DESAM RS12350
gene id: 1121451:DESAM_RS12350
uniprot id: L0RD11
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS02085
gene id: 1121451:DESAM_RS02085
uniprot id: L0R8F9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1121451:DESAM RS12100
gene id: 1121451:DESAM_RS12100
uniprot id: L0REF2
names: Similarity
messages: Belongs to the GcvT family.

1121451:DESAM RS11690
gene id: 1121451:DESAM_RS11690
uniprot id: L0RCJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1121451:DESAM RS11575
gene id: 1121451:DESAM_RS11575
uniprot id: L0RCH6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1121451:DESAM RS04005
gene id: 1121451:DESAM_RS04005
uniprot id: L0R9K0
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1121451:DESAM RS06495
gene id: 1121451:DESAM_RS06495
uniprot id: L0RCZ6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1121451:DESAM RS14720
gene id: 1121451:DESAM_RS14720
uniprot id: L0RHT1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121451:DESAM RS10955
gene id: 1121451:DESAM_RS10955
uniprot id: L0RDS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS06140
gene id: 1121451:DESAM_RS06140
uniprot id: L0R9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1121451:DESAM RS02435
gene id: 1121451:DESAM_RS02435
uniprot id: L0R740
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1121451:DESAM RS12565
gene id: 1121451:DESAM_RS12565
uniprot id: L0RD62
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121451:DESAM RS01895
gene id: 1121451:DESAM_RS01895
uniprot id: L0R8B8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00420
gene id: 1121451:DESAM_RS00420
uniprot id: L0R5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1121451:DESAM RS03565
gene id: 1121451:DESAM_RS03565
uniprot id: L0R986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1121451:DESAM RS15250
gene id: 1121451:DESAM_RS15250
uniprot id: L0REP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1121451:DESAM RS12770
gene id: 1121451:DESAM_RS12770
uniprot id: L0RD84
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS11625
gene id: 1121451:DESAM_RS11625
uniprot id: L0RCI4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1121451:DESAM RS05080
gene id: 1121451:DESAM_RS05080
uniprot id: L0RC19
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121451:DESAM RS13605
gene id: 1121451:DESAM_RS13605
uniprot id: L0RH86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS03940
gene id: 1121451:DESAM_RS03940
uniprot id: L0RBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS05490
gene id: 1121451:DESAM_RS05490
uniprot id: L0RAE6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1121451:DESAM RS11805
gene id: 1121451:DESAM_RS11805
uniprot id: L0RE98
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1121451:DESAM RS04225
gene id: 1121451:DESAM_RS04225
uniprot id: L0R854
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS11630
gene id: 1121451:DESAM_RS11630
uniprot id: L0RE87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1121451:DESAM RS09180
gene id: 1121451:DESAM_RS09180
uniprot id: L0RB24
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1121451:DESAM RS13395
gene id: 1121451:DESAM_RS13395
uniprot id: L0RF76
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS11725
gene id: 1121451:DESAM_RS11725
uniprot id: L0RG34
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS03985
gene id: 1121451:DESAM_RS03985
uniprot id: L0RBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121451:DESAM RS11155
gene id: 1121451:DESAM_RS11155
uniprot id: L0RDX1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1121451:DESAM RS14910
gene id: 1121451:DESAM_RS14910
uniprot id: L0RG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1121451:DESAM RS14850
gene id: 1121451:DESAM_RS14850
uniprot id: L0REE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1121451:DESAM RS04435
gene id: 1121451:DESAM_RS04435
uniprot id: L0R886
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1121451:DESAM RS14565
gene id: 1121451:DESAM_RS14565
uniprot id: L0RFX4
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08750
gene id: 1121451:DESAM_RS08750
uniprot id: L0RCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS07845
gene id: 1121451:DESAM_RS07845
uniprot id: L0RDP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121451:DESAM RS02065
gene id: 1121451:DESAM_RS02065
uniprot id: L0RA77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS11305
gene id: 1121451:DESAM_RS11305
uniprot id: L0RFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS06225
gene id: 1121451:DESAM_RS06225
uniprot id: L0RCP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS11505
gene id: 1121451:DESAM_RS11505
uniprot id: L0RCJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1121451:DESAM RS16045
gene id: 1121451:DESAM_RS16045
uniprot id: L0RF77
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS01420
gene id: 1121451:DESAM_RS01420
uniprot id: L0R6H5
names: Similarity
messages: Belongs to the HsdR family.

1121451:DESAM RS12330
gene id: 1121451:DESAM_RS12330
uniprot id: L0REM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1121451:DESAM RS15395
gene id: 1121451:DESAM_RS15395
uniprot id: L0RES0
names: Similarity
messages: Belongs to the HypD family.

1121451:DESAM RS05200
gene id: 1121451:DESAM_RS05200
uniprot id: L0RAA7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1121451:DESAM RS12160
gene id: 1121451:DESAM_RS12160
uniprot id: L0RCX4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1121451:DESAM RS02270
gene id: 1121451:DESAM_RS02270
uniprot id: L0R8F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1121451:DESAM RS12610
gene id: 1121451:DESAM_RS12610
uniprot id: L0RD43
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09225
gene id: 1121451:DESAM_RS09225
uniprot id: L0RCP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121451:DESAM RS11360
gene id: 1121451:DESAM_RS11360
uniprot id: L0RCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1121451:DESAM RS15200
gene id: 1121451:DESAM_RS15200
uniprot id: L0REM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1121451:DESAM RS07195
gene id: 1121451:DESAM_RS07195
uniprot id: L0RBG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1121451:DESAM RS02605
gene id: 1121451:DESAM_RS02605
uniprot id: L0R8L9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1121451:DESAM RS13155
gene id: 1121451:DESAM_RS13155
uniprot id: L0RGV0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS14770
gene id: 1121451:DESAM_RS14770
uniprot id: L0RHT8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121451:DESAM RS08150
gene id: 1121451:DESAM_RS08150
uniprot id: L0RDV1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121451:DESAM RS10365
gene id: 1121451:DESAM_RS10365
uniprot id: L0RF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15330
gene id: 1121451:DESAM_RS15330
uniprot id: L0RGD4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1121451:DESAM RS12225
gene id: 1121451:DESAM_RS12225
uniprot id: L0RCV7
names: Similarity
messages: Belongs to the HupF/HypC family.

1121451:DESAM RS14220
gene id: 1121451:DESAM_RS14220
uniprot id: L0RFR0
names: Subunit
messages: Heterodimer of a large and a small subunit.

1121451:DESAM RS15280
gene id: 1121451:DESAM_RS15280
uniprot id: L0RES7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1121451:DESAM RS15350
gene id: 1121451:DESAM_RS15350
uniprot id: L0RGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1121451:DESAM RS11955
gene id: 1121451:DESAM_RS11955
uniprot id: L0RCQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1121451:DESAM RS15995
gene id: 1121451:DESAM_RS15995
uniprot id: L0RFA2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1121451:DESAM RS13795
gene id: 1121451:DESAM_RS13795
uniprot id: L0RDV0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121451:DESAM RS05545
gene id: 1121451:DESAM_RS05545
uniprot id: L0R8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1121451:DESAM RS12915
gene id: 1121451:DESAM_RS12915
uniprot id: L0RGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1121451:DESAM RS10010
gene id: 1121451:DESAM_RS10010
uniprot id: L0RBK5
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS03605
gene id: 1121451:DESAM_RS03605
uniprot id: L0R9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1121451:DESAM RS09010
gene id: 1121451:DESAM_RS09010
uniprot id: L0RB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1121451:DESAM RS15185
gene id: 1121451:DESAM_RS15185
uniprot id: L0RGA6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS04750
gene id: 1121451:DESAM_RS04750
uniprot id: L0RBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121451:DESAM RS01500
gene id: 1121451:DESAM_RS01500
uniprot id: L0R6J3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1121451:DESAM RS11595
gene id: 1121451:DESAM_RS11595
uniprot id: L0RE57
names: Similarity
messages: Belongs to the threonine synthase family.

1121451:DESAM RS06470
gene id: 1121451:DESAM_RS06470
uniprot id: L0RB40
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1121451:DESAM RS03075
gene id: 1121451:DESAM_RS03075
uniprot id: L0RAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS12170
gene id: 1121451:DESAM_RS12170
uniprot id: L0RGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1121451:DESAM RS00495
gene id: 1121451:DESAM_RS00495
uniprot id: L0R7C8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1121451:DESAM RS15890
gene id: 1121451:DESAM_RS15890
uniprot id: L0RF32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1121451:DESAM RS12290
gene id: 1121451:DESAM_RS12290
uniprot id: L0REJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS07090
gene id: 1121451:DESAM_RS07090
uniprot id: L0R9W2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS11410
gene id: 1121451:DESAM_RS11410
uniprot id: L0RE46
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS13380
gene id: 1121451:DESAM_RS13380
uniprot id: L0RDN8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121451:DESAM RS15325
gene id: 1121451:DESAM_RS15325
uniprot id: L0RET9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121451:DESAM RS03650
gene id: 1121451:DESAM_RS03650
uniprot id: L0RB38
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1121451:DESAM RS14405
gene id: 1121451:DESAM_RS14405
uniprot id: L0RFU1
names: Similarity
messages: Belongs to the hemerythrin family.

1121451:DESAM RS07220
gene id: 1121451:DESAM_RS07220
uniprot id: L0R9W0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1121451:DESAM RS13960
gene id: 1121451:DESAM_RS13960
uniprot id: L0RE02
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1121451:DESAM RS04980
gene id: 1121451:DESAM_RS04980
uniprot id: L0RC01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1121451:DESAM RS07490
gene id: 1121451:DESAM_RS07490
uniprot id: L0RA35
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1121451:DESAM RS09290
gene id: 1121451:DESAM_RS09290
uniprot id: L0RCT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS02050
gene id: 1121451:DESAM_RS02050
uniprot id: L0R6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121451:DESAM RS02665
gene id: 1121451:DESAM_RS02665
uniprot id: L0RAJ2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121451:DESAM RS15960
gene id: 1121451:DESAM_RS15960
uniprot id: L0RGQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121451:DESAM RS08630
gene id: 1121451:DESAM_RS08630
uniprot id: L0RE61
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1121451:DESAM RS05705
gene id: 1121451:DESAM_RS05705
uniprot id: L0RCD0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121451:DESAM RS16540
gene id: 1121451:DESAM_RS16540
uniprot id: L0RIW9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS07600
gene id: 1121451:DESAM_RS07600
uniprot id: L0RBP3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1121451:DESAM RS11190
gene id: 1121451:DESAM_RS11190
uniprot id: L0RDX2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121451:DESAM RS01910
gene id: 1121451:DESAM_RS01910
uniprot id: L0R6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121451:DESAM RS00150
gene id: 1121451:DESAM_RS00150
uniprot id: L0R732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1121451:DESAM RS14710
gene id: 1121451:DESAM_RS14710
uniprot id: L0REF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1121451:DESAM RS12075
gene id: 1121451:DESAM_RS12075
uniprot id: L0REE5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1121451:DESAM RS04795
gene id: 1121451:DESAM_RS04795
uniprot id: L0RBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS04810
gene id: 1121451:DESAM_RS04810
uniprot id: L0R8G5
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS04465
gene id: 1121451:DESAM_RS04465
uniprot id: L0R9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS12810
gene id: 1121451:DESAM_RS12810
uniprot id: L0RD95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10310
gene id: 1121451:DESAM_RS10310
uniprot id: L0RDD1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1121451:DESAM RS15455
gene id: 1121451:DESAM_RS15455
uniprot id: L0RGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1121451:DESAM RS12255
gene id: 1121451:DESAM_RS12255
uniprot id: L0REK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1121451:DESAM RS15650
gene id: 1121451:DESAM_RS15650
uniprot id: L0RF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS06975
gene id: 1121451:DESAM_RS06975
uniprot id: L0RD88
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1121451:DESAM RS03585
gene id: 1121451:DESAM_RS03585
uniprot id: L0RB23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1121451:DESAM RS11720
gene id: 1121451:DESAM_RS11720
uniprot id: L0REA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1121451:DESAM RS02005
gene id: 1121451:DESAM_RS02005
uniprot id: L0R8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121451:DESAM RS05250
gene id: 1121451:DESAM_RS05250
uniprot id: L0RAB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12445
gene id: 1121451:DESAM_RS12445
uniprot id: L0REN0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1121451:DESAM RS06950
gene id: 1121451:DESAM_RS06950
uniprot id: L0RD85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS13115
gene id: 1121451:DESAM_RS13115
uniprot id: L0RDF9
names: Subcellular Location Annotation
messages: Cytoplasm

1121451:DESAM RS09240
gene id: 1121451:DESAM_RS09240
uniprot id: L0RCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1121451:DESAM RS02440
gene id: 1121451:DESAM_RS02440
uniprot id: L0R718
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1121451:DESAM RS05020
gene id: 1121451:DESAM_RS05020
uniprot id: L0R8K5
names: Similarity
messages: Belongs to the AOR/FOR family.

1121451:DESAM RS15085
gene id: 1121451:DESAM_RS15085
uniprot id: L0REJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1121451:DESAM RS02245
gene id: 1121451:DESAM_RS02245
uniprot id: L0R8E8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1121451:DESAM RS06435
gene id: 1121451:DESAM_RS06435
uniprot id: L0RAZ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS02820
gene id: 1121451:DESAM_RS02820
uniprot id: L0R7C2
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS16320
gene id: 1121451:DESAM_RS16320
uniprot id: L0RGW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS02955
gene id: 1121451:DESAM_RS02955
uniprot id: L0R8Z0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1121451:DESAM RS05460
gene id: 1121451:DESAM_RS05460
uniprot id: L0R8U1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121451:DESAM RS12620
gene id: 1121451:DESAM_RS12620
uniprot id: L0RET3
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS06105
gene id: 1121451:DESAM_RS06105
uniprot id: L0RAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1121451:DESAM RS08910
gene id: 1121451:DESAM_RS08910
uniprot id: L0RCI5
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

1121451:DESAM RS10675
gene id: 1121451:DESAM_RS10675
uniprot id: L0RBX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1121451:DESAM RS03430
gene id: 1121451:DESAM_RS03430
uniprot id: L0R953
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1121451:DESAM RS05050
gene id: 1121451:DESAM_RS05050
uniprot id: L0R8K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS12775
gene id: 1121451:DESAM_RS12775
uniprot id: L0RDB0
names: Similarity
messages: Belongs to the FeoA family.

1121451:DESAM RS04910
gene id: 1121451:DESAM_RS04910
uniprot id: L0RA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS16445
gene id: 1121451:DESAM_RS16445
uniprot id: L0RIV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1121451:DESAM RS12245
gene id: 1121451:DESAM_RS12245
uniprot id: L0RCW2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1121451:DESAM RS10455
gene id: 1121451:DESAM_RS10455
uniprot id: L0RDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1121451:DESAM RS06400
gene id: 1121451:DESAM_RS06400
uniprot id: L0R9F7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS07760
gene id: 1121451:DESAM_RS07760
uniprot id: L0RBS2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1121451:DESAM RS11585
gene id: 1121451:DESAM_RS11585
uniprot id: L0RE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1121451:DESAM RS02100
gene id: 1121451:DESAM_RS02100
uniprot id: L0R6X1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS15230
gene id: 1121451:DESAM_RS15230
uniprot id: L0RER6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1121451:DESAM RS13655
gene id: 1121451:DESAM_RS13655
uniprot id: L0RDV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS05795
gene id: 1121451:DESAM_RS05795
uniprot id: L0R917
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121451:DESAM RS05160
gene id: 1121451:DESAM_RS05160
uniprot id: L0RA74
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS14270
gene id: 1121451:DESAM_RS14270
uniprot id: L0RFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1121451:DESAM RS16630
gene id: 1121451:DESAM_RS16630
uniprot id: L0RCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS09865
gene id: 1121451:DESAM_RS09865
uniprot id: L0RBE7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1121451:DESAM RS16160
gene id: 1121451:DESAM_RS16160
uniprot id: L0RGT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1121451:DESAM RS12495
gene id: 1121451:DESAM_RS12495
uniprot id: L0RD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1121451:DESAM RS00790
gene id: 1121451:DESAM_RS00790
uniprot id: L0R651
names: Similarity
messages: Belongs to the P(II) protein family.

1121451:DESAM RS13080
gene id: 1121451:DESAM_RS13080
uniprot id: L0RGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1121451:DESAM RS14455
gene id: 1121451:DESAM_RS14455
uniprot id: L0RHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1121451:DESAM RS03240
gene id: 1121451:DESAM_RS03240
uniprot id: L0R7K1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1121451:DESAM RS15245
gene id: 1121451:DESAM_RS15245
uniprot id: L0RG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1121451:DESAM RS08890
gene id: 1121451:DESAM_RS08890
uniprot id: L0RAX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1121451:DESAM RS02160
gene id: 1121451:DESAM_RS02160
uniprot id: L0R6W7
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09995
gene id: 1121451:DESAM_RS09995
uniprot id: L0RF09
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121451:DESAM RS16215
gene id: 1121451:DESAM_RS16215
uniprot id: L0RFD5
names: Similarity
messages: Belongs to the MlaA family.

1121451:DESAM RS03930
gene id: 1121451:DESAM_RS03930
uniprot id: L0R7Z5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1121451:DESAM RS10905
gene id: 1121451:DESAM_RS10905
uniprot id: L0RC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS10865
gene id: 1121451:DESAM_RS10865
uniprot id: L0RC52
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121451:DESAM RS06065
gene id: 1121451:DESAM_RS06065
uniprot id: L0RCK3
names: Similarity
messages: Belongs to the ros/MucR family.

1121451:DESAM RS10585
gene id: 1121451:DESAM_RS10585
uniprot id: L0RFB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1121451:DESAM RS00785
gene id: 1121451:DESAM_RS00785
uniprot id: L0R7G8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS03425
gene id: 1121451:DESAM_RS03425
uniprot id: L0RAY9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1121451:DESAM RS05805
gene id: 1121451:DESAM_RS05805
uniprot id: L0RCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS06775
gene id: 1121451:DESAM_RS06775
uniprot id: L0RB75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1121451:DESAM RS13075
gene id: 1121451:DESAM_RS13075
uniprot id: L0RF23
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1121451:DESAM RS10250
gene id: 1121451:DESAM_RS10250
uniprot id: L0RD98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121451:DESAM RS10660
gene id: 1121451:DESAM_RS10660
uniprot id: L0RC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS01675
gene id: 1121451:DESAM_RS01675
uniprot id: L0R840
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1121451:DESAM RS12730
gene id: 1121451:DESAM_RS12730
uniprot id: L0REV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS15850
gene id: 1121451:DESAM_RS15850
uniprot id: L0RF48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1121451:DESAM RS11115
gene id: 1121451:DESAM_RS11115
uniprot id: L0RDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1121451:DESAM RS13505
gene id: 1121451:DESAM_RS13505
uniprot id: L0RFA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1121451:DESAM RS10615
gene id: 1121451:DESAM_RS10615
uniprot id: L0RBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15390
gene id: 1121451:DESAM_RS15390
uniprot id: L0RGC3
names: Similarity
messages: Belongs to the HypE family.

1121451:DESAM RS13055
gene id: 1121451:DESAM_RS13055
uniprot id: L0RGS6
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS05875
gene id: 1121451:DESAM_RS05875
uniprot id: L0RCG2
names: Similarity
messages: Belongs to the glutamate synthase family.

1121451:DESAM RS01745
gene id: 1121451:DESAM_RS01745
uniprot id: L0R857
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121451:DESAM RS03205
gene id: 1121451:DESAM_RS03205
uniprot id: L0R7J4
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS00500
gene id: 1121451:DESAM_RS00500
uniprot id: L0R940
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1121451:DESAM RS15660
gene id: 1121451:DESAM_RS15660
uniprot id: L0RI98
names: Subunit
messages: Homotetramer.

1121451:DESAM RS10215
gene id: 1121451:DESAM_RS10215
uniprot id: L0RDB1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1121451:DESAM RS15735
gene id: 1121451:DESAM_RS15735
uniprot id: L0RGK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1121451:DESAM RS03580
gene id: 1121451:DESAM_RS03580
uniprot id: L0R9B7
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS14090
gene id: 1121451:DESAM_RS14090
uniprot id: L0RDZ2
names: Subcellular Location Annotation
messages: Virion

1121451:DESAM RS15290
gene id: 1121451:DESAM_RS15290
uniprot id: L0RI32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1121451:DESAM RS15320
gene id: 1121451:DESAM_RS15320
uniprot id: L0REQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1121451:DESAM RS16115
gene id: 1121451:DESAM_RS16115
uniprot id: L0RIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1121451:DESAM RS14840
gene id: 1121451:DESAM_RS14840
uniprot id: L0RHV3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1121451:DESAM RS06295
gene id: 1121451:DESAM_RS06295
uniprot id: L0R9C9
names: Similarity
messages: Belongs to the P(II) protein family.

1121451:DESAM RS13305
gene id: 1121451:DESAM_RS13305
uniprot id: L0RDK4
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1121451:DESAM RS08050
gene id: 1121451:DESAM_RS08050
uniprot id: L0RBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS02070
gene id: 1121451:DESAM_RS02070
uniprot id: L0R8B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1121451:DESAM RS02060
gene id: 1121451:DESAM_RS02060
uniprot id: L0R8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121451:DESAM RS13885
gene id: 1121451:DESAM_RS13885
uniprot id: L0RFH8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1121451:DESAM RS14000
gene id: 1121451:DESAM_RS14000
uniprot id: L0RDX6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1121451:DESAM RS13120
gene id: 1121451:DESAM_RS13120
uniprot id: L0RDI5
names: Similarity
messages: Belongs to the YggT family.

1121451:DESAM RS14310
gene id: 1121451:DESAM_RS14310
uniprot id: L0RE33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121451:DESAM RS06040
gene id: 1121451:DESAM_RS06040
uniprot id: L0R975
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1121451:DESAM RS06180
gene id: 1121451:DESAM_RS06180
uniprot id: L0RAU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1121451:DESAM RS03745
gene id: 1121451:DESAM_RS03745
uniprot id: L0R9E9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121451:DESAM RS04515
gene id: 1121451:DESAM_RS04515
uniprot id: L0R9U4
names: Similarity
messages: Belongs to the peptidase M16 family.

1121451:DESAM RS02690
gene id: 1121451:DESAM_RS02690
uniprot id: L0R8T6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121451:DESAM RS01060
gene id: 1121451:DESAM_RS01060
uniprot id: L0R7M9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1121451:DESAM RS11885
gene id: 1121451:DESAM_RS11885
uniprot id: L0RCS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS06615
gene id: 1121451:DESAM_RS06615
uniprot id: L0R9K1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1121451:DESAM RS14255
gene id: 1121451:DESAM_RS14255
uniprot id: L0RFP2
names: Similarity
messages: Belongs to the FeoA family.

1121451:DESAM RS13715
gene id: 1121451:DESAM_RS13715
uniprot id: L0RHA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1121451:DESAM RS12300
gene id: 1121451:DESAM_RS12300
uniprot id: L0RCZ9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS03755
gene id: 1121451:DESAM_RS03755
uniprot id: L0R9C8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS04360
gene id: 1121451:DESAM_RS04360
uniprot id: L0RBN3
names: Similarity
messages: Belongs to the UPF0434 family.

1121451:DESAM RS01585
gene id: 1121451:DESAM_RS01585
uniprot id: L0R9T5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1121451:DESAM RS05770
gene id: 1121451:DESAM_RS05770
uniprot id: L0R912
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1121451:DESAM RS10985
gene id: 1121451:DESAM_RS10985
uniprot id: L0RFL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1121451:DESAM RS00510
gene id: 1121451:DESAM_RS00510
uniprot id: L0R5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1121451:DESAM RS10775
gene id: 1121451:DESAM_RS10775
uniprot id: L0RDN4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121451:DESAM RS13095
gene id: 1121451:DESAM_RS13095
uniprot id: L0RDI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121451:DESAM RS11850
gene id: 1121451:DESAM_RS11850
uniprot id: L0RG56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121451:DESAM RS08650
gene id: 1121451:DESAM_RS08650
uniprot id: L0RCC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1121451:DESAM RS12345
gene id: 1121451:DESAM_RS12345
uniprot id: L0RCY0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS13295
gene id: 1121451:DESAM_RS13295
uniprot id: L0RGY6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS15255
gene id: 1121451:DESAM_RS15255
uniprot id: L0RES1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1121451:DESAM RS08555
gene id: 1121451:DESAM_RS08555
uniprot id: L0RCB2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS06370
gene id: 1121451:DESAM_RS06370
uniprot id: L0R9E7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1121451:DESAM RS11840
gene id: 1121451:DESAM_RS11840
uniprot id: L0RCR2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1121451:DESAM RS13690
gene id: 1121451:DESAM_RS13690
uniprot id: L0RH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS16625
gene id: 1121451:DESAM_RS16625
uniprot id: L0RBU7
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS05360
gene id: 1121451:DESAM_RS05360
uniprot id: L0RAB6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1121451:DESAM RS11775
gene id: 1121451:DESAM_RS11775
uniprot id: L0RG43
names: Similarity
messages: Belongs to the aspartokinase family.

1121451:DESAM RS07035
gene id: 1121451:DESAM_RS07035
uniprot id: L0RDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS12315
gene id: 1121451:DESAM_RS12315
uniprot id: L0REK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Periplasm

1121451:DESAM RS10940
gene id: 1121451:DESAM_RS10940
uniprot id: L0RDQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS09275
gene id: 1121451:DESAM_RS09275
uniprot id: L0RCQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1121451:DESAM RS15680
gene id: 1121451:DESAM_RS15680
uniprot id: L0RGK2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1121451:DESAM RS03100
gene id: 1121451:DESAM_RS03100
uniprot id: L0RAS7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS09985
gene id: 1121451:DESAM_RS09985
uniprot id: L0RBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121451:DESAM RS01875
gene id: 1121451:DESAM_RS01875
uniprot id: L0R6T0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1121451:DESAM RS08495
gene id: 1121451:DESAM_RS08495
uniprot id: L0RAM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS04510
gene id: 1121451:DESAM_RS04510
uniprot id: L0RBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

1121451:DESAM RS11150
gene id: 1121451:DESAM_RS11150
uniprot id: L0RCB4
names: Similarity
messages: Belongs to the thioredoxin family.

1121451:DESAM RS11525
gene id: 1121451:DESAM_RS11525
uniprot id: L0RCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS02210
gene id: 1121451:DESAM_RS02210
uniprot id: L0R8I1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1121451:DESAM RS10945
gene id: 1121451:DESAM_RS10945
uniprot id: L0RC43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1121451:DESAM RS11800
gene id: 1121451:DESAM_RS11800
uniprot id: L0RG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1121451:DESAM RS11730
gene id: 1121451:DESAM_RS11730
uniprot id: L0RE84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121451:DESAM RS11665
gene id: 1121451:DESAM_RS11665
uniprot id: L0RE71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1121451:DESAM RS15525
gene id: 1121451:DESAM_RS15525
uniprot id: L0RGG8
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1121451:DESAM RS06805
gene id: 1121451:DESAM_RS06805
uniprot id: L0R9Q2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS02430
gene id: 1121451:DESAM_RS02430
uniprot id: L0R8I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1121451:DESAM RS08490
gene id: 1121451:DESAM_RS08490
uniprot id: L0RC81
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1121451:DESAM RS15790
gene id: 1121451:DESAM_RS15790
uniprot id: L0RF10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1121451:DESAM RS05245
gene id: 1121451:DESAM_RS05245
uniprot id: L0R8P7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121451:DESAM RS12265
gene id: 1121451:DESAM_RS12265
uniprot id: L0REJ0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121451:DESAM RS10440
gene id: 1121451:DESAM_RS10440
uniprot id: L0RBS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1121451:DESAM RS03495
gene id: 1121451:DESAM_RS03495
uniprot id: L0R971
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1121451:DESAM RS01835
gene id: 1121451:DESAM_RS01835
uniprot id: L0R8A4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1121451:DESAM RS06340
gene id: 1121451:DESAM_RS06340
uniprot id: L0RAX2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1121451:DESAM RS13090
gene id: 1121451:DESAM_RS13090
uniprot id: L0RDF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS04280
gene id: 1121451:DESAM_RS04280
uniprot id: L0R9T7
names: Similarity
messages: Belongs to the peptidase C56 family.

1121451:DESAM RS14760
gene id: 1121451:DESAM_RS14760
uniprot id: L0REG2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121451:DESAM RS00525
gene id: 1121451:DESAM_RS00525
uniprot id: L0R946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1121451:DESAM RS10135
gene id: 1121451:DESAM_RS10135
uniprot id: L0RF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS15755
gene id: 1121451:DESAM_RS15755
uniprot id: L0RIC9
names: Similarity
messages: Belongs to the UPF0045 family.

1121451:DESAM RS09270
gene id: 1121451:DESAM_RS09270
uniprot id: L0REM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1121451:DESAM RS03170
gene id: 1121451:DESAM_RS03170
uniprot id: L0RAU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1121451:DESAM RS11230
gene id: 1121451:DESAM_RS11230
uniprot id: L0RE09
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS05425
gene id: 1121451:DESAM_RS05425
uniprot id: L0RC83
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1121451:DESAM RS09910
gene id: 1121451:DESAM_RS09910
uniprot id: L0RBF6
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121451:DESAM RS13390
gene id: 1121451:DESAM_RS13390
uniprot id: L0RH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1121451:DESAM RS10070
gene id: 1121451:DESAM_RS10070
uniprot id: L0RBI7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1121451:DESAM RS14860
gene id: 1121451:DESAM_RS14860
uniprot id: L0RG37
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1121451:DESAM RS12560
gene id: 1121451:DESAM_RS12560
uniprot id: L0RD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121451:DESAM RS03990
gene id: 1121451:DESAM_RS03990
uniprot id: L0R9H7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1121451:DESAM RS03570
gene id: 1121451:DESAM_RS03570
uniprot id: L0R7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1121451:DESAM RS03975
gene id: 1121451:DESAM_RS03975
uniprot id: L0R801
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1121451:DESAM RS10630
gene id: 1121451:DESAM_RS10630
uniprot id: L0RFC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1121451:DESAM RS06195
gene id: 1121451:DESAM_RS06195
uniprot id: L0RAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1121451:DESAM RS14915
gene id: 1121451:DESAM_RS14915
uniprot id: L0REG0
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1121451:DESAM RS05140
gene id: 1121451:DESAM_RS05140
uniprot id: L0R8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1121451:DESAM RS09500
gene id: 1121451:DESAM_RS09500
uniprot id: L0RB76
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1121451:DESAM RS04205
gene id: 1121451:DESAM_RS04205
uniprot id: L0R856
names: Similarity
messages: Belongs to the UPF0111 family.

1121451:DESAM RS12735
gene id: 1121451:DESAM_RS12735
uniprot id: L0RGM1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS04730
gene id: 1121451:DESAM_RS04730
uniprot id: L0R9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1121451:DESAM RS03850
gene id: 1121451:DESAM_RS03850
uniprot id: L0R9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1121451:DESAM RS10700
gene id: 1121451:DESAM_RS10700
uniprot id: L0RC14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS07190
gene id: 1121451:DESAM_RS07190
uniprot id: L0RDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS02185
gene id: 1121451:DESAM_RS02185
uniprot id: L0R6X0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1121451:DESAM RS03115
gene id: 1121451:DESAM_RS03115
uniprot id: L0R919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1121451:DESAM RS15725
gene id: 1121451:DESAM_RS15725
uniprot id: L0RF24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1121451:DESAM RS15590
gene id: 1121451:DESAM_RS15590
uniprot id: L0RGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS09260
gene id: 1121451:DESAM_RS09260
uniprot id: L0RB64
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1121451:DESAM RS15815
gene id: 1121451:DESAM_RS15815
uniprot id: L0RF43
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS01620
gene id: 1121451:DESAM_RS01620
uniprot id: L0R6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1121451:DESAM RS07385
gene id: 1121451:DESAM_RS07385
uniprot id: L0RBJ5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1121451:DESAM RS14730
gene id: 1121451:DESAM_RS14730
uniprot id: L0REC2
names: Similarity
messages: Belongs to the peptidase M29 family.

1121451:DESAM RS13495
gene id: 1121451:DESAM_RS13495
uniprot id: L0RFA4
names: Similarity
messages: Belongs to the CutA family.

1121451:DESAM RS08235
gene id: 1121451:DESAM_RS08235
uniprot id: L0RC30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1121451:DESAM RS03250
gene id: 1121451:DESAM_RS03250
uniprot id: L0R945
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1121451:DESAM RS14245
gene id: 1121451:DESAM_RS14245
uniprot id: L0RFR3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1121451:DESAM RS02890
gene id: 1121451:DESAM_RS02890
uniprot id: L0R7C4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1121451:DESAM RS10150
gene id: 1121451:DESAM_RS10150
uniprot id: L0RF40
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1121451:DESAM RS14985
gene id: 1121451:DESAM_RS14985
uniprot id: L0RG41
names: Similarity
messages: Belongs to the Ahb/Nir family.

1121451:DESAM RS15165
gene id: 1121451:DESAM_RS15165
uniprot id: L0RG98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1121451:DESAM RS14140
gene id: 1121451:DESAM_RS14140
uniprot id: L0RE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15150
gene id: 1121451:DESAM_RS15150
uniprot id: L0RG76
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1121451:DESAM RS02280
gene id: 1121451:DESAM_RS02280
uniprot id: L0R6Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1121451:DESAM RS10190
gene id: 1121451:DESAM_RS10190
uniprot id: L0RDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1121451:DESAM RS04165
gene id: 1121451:DESAM_RS04165
uniprot id: L0RBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121451:DESAM RS06085
gene id: 1121451:DESAM_RS06085
uniprot id: L0RAU9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121451:DESAM RS02200
gene id: 1121451:DESAM_RS02200
uniprot id: L0R6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS11675
gene id: 1121451:DESAM_RS11675
uniprot id: L0RE97
names: Similarity
messages: Belongs to the UPF0166 family.

1121451:DESAM RS11440
gene id: 1121451:DESAM_RS11440
uniprot id: L0RFY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1121451:DESAM RS15835
gene id: 1121451:DESAM_RS15835
uniprot id: L0RF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1121451:DESAM RS15945
gene id: 1121451:DESAM_RS15945
uniprot id: L0RGQ8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1121451:DESAM RS13825
gene id: 1121451:DESAM_RS13825
uniprot id: L0RDY4
names: Similarity
messages: Belongs to the type III secretion exporter family.

1121451:DESAM RS04010
gene id: 1121451:DESAM_RS04010
uniprot id: L0RBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1121451:DESAM RS15545
gene id: 1121451:DESAM_RS15545
uniprot id: L0RGH5
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09975
gene id: 1121451:DESAM_RS09975
uniprot id: L0RD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1121451:DESAM RS00360
gene id: 1121451:DESAM_RS00360
uniprot id: L0R911
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1121451:DESAM RS09495
gene id: 1121451:DESAM_RS09495
uniprot id: L0RCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26C family.
messages: Periplasm

1121451:DESAM RS15120
gene id: 1121451:DESAM_RS15120
uniprot id: L0RI05
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121451:DESAM RS05290
gene id: 1121451:DESAM_RS05290
uniprot id: L0R8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1121451:DESAM RS06405
gene id: 1121451:DESAM_RS06405
uniprot id: L0RB11
names: Similarity
messages: Belongs to the DEAD box helicase family.

1121451:DESAM RS06245
gene id: 1121451:DESAM_RS06245
uniprot id: L0R9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS13285
gene id: 1121451:DESAM_RS13285
uniprot id: L0RDJ8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS15440
gene id: 1121451:DESAM_RS15440
uniprot id: L0RET1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121451:DESAM RS10925
gene id: 1121451:DESAM_RS10925
uniprot id: L0RDP7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1121451:DESAM RS15220
gene id: 1121451:DESAM_RS15220
uniprot id: L0RG92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS08775
gene id: 1121451:DESAM_RS08775
uniprot id: L0RCD8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08580
gene id: 1121451:DESAM_RS08580
uniprot id: L0RE49
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1121451:DESAM RS10360
gene id: 1121451:DESAM_RS10360
uniprot id: L0RDE1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121451:DESAM RS13890
gene id: 1121451:DESAM_RS13890
uniprot id: L0RDW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1121451:DESAM RS10695
gene id: 1121451:DESAM_RS10695
uniprot id: L0RDJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1121451:DESAM RS08980
gene id: 1121451:DESAM_RS08980
uniprot id: L0RCJ9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1121451:DESAM RS04775
gene id: 1121451:DESAM_RS04775
uniprot id: L0RBW0
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS14275
gene id: 1121451:DESAM_RS14275
uniprot id: L0RHJ4
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS05150
gene id: 1121451:DESAM_RS05150
uniprot id: L0RA97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1121451:DESAM RS12200
gene id: 1121451:DESAM_RS12200
uniprot id: L0REH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1121451:DESAM RS09655
gene id: 1121451:DESAM_RS09655
uniprot id: L0RCX3
names: Similarity
messages: Belongs to the DprA/Smf family.

1121451:DESAM RS12030
gene id: 1121451:DESAM_RS12030
uniprot id: L0REG3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1121451:DESAM RS04235
gene id: 1121451:DESAM_RS04235
uniprot id: L0RBL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

1121451:DESAM RS12065
gene id: 1121451:DESAM_RS12065
uniprot id: L0REG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1121451:DESAM RS13175
gene id: 1121451:DESAM_RS13175
uniprot id: L0RF42
names: Similarity
messages: Belongs to the LOG family.

1121451:DESAM RS07920
gene id: 1121451:DESAM_RS07920
uniprot id: L0RAC4
names: Similarity
messages: Belongs to the universal stress protein A family.

1121451:DESAM RS13880
gene id: 1121451:DESAM_RS13880
uniprot id: L0RHD0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1121451:DESAM RS04130
gene id: 1121451:DESAM_RS04130
uniprot id: L0R847
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS09135
gene id: 1121451:DESAM_RS09135
uniprot id: L0RCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS13675
gene id: 1121451:DESAM_RS13675
uniprot id: L0RDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1121451:DESAM RS08160
gene id: 1121451:DESAM_RS08160
uniprot id: L0RAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1121451:DESAM RS15640
gene id: 1121451:DESAM_RS15640
uniprot id: L0RGI0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08875
gene id: 1121451:DESAM_RS08875
uniprot id: L0RCK2
names: Similarity
messages: Belongs to the RecJ family.

1121451:DESAM RS00515
gene id: 1121451:DESAM_RS00515
uniprot id: L0R5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1121451:DESAM RS15295
gene id: 1121451:DESAM_RS15295
uniprot id: L0RGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1121451:DESAM RS11895
gene id: 1121451:DESAM_RS11895
uniprot id: L0RG64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1121451:DESAM RS14265
gene id: 1121451:DESAM_RS14265
uniprot id: L0RE59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121451:DESAM RS13265
gene id: 1121451:DESAM_RS13265
uniprot id: L0RDL4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1121451:DESAM RS02170
gene id: 1121451:DESAM_RS02170
uniprot id: L0RA94
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1121451:DESAM RS01645
gene id: 1121451:DESAM_RS01645
uniprot id: L0R6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1121451:DESAM RS01660
gene id: 1121451:DESAM_RS01660
uniprot id: L0R808
names: Subunit
messages: Heterodimer of a large and a small subunit.

1121451:DESAM RS11705
gene id: 1121451:DESAM_RS11705
uniprot id: L0RE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1121451:DESAM RS13575
gene id: 1121451:DESAM_RS13575
uniprot id: L0RFD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1121451:DESAM RS13800
gene id: 1121451:DESAM_RS13800
uniprot id: L0RDY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121451:DESAM RS11450
gene id: 1121451:DESAM_RS11450
uniprot id: L0RCG1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1121451:DESAM RS11160
gene id: 1121451:DESAM_RS11160
uniprot id: L0RFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1121451:DESAM RS04545
gene id: 1121451:DESAM_RS04545
uniprot id: L0R8A3
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS06490
gene id: 1121451:DESAM_RS06490
uniprot id: L0RB50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1121451:DESAM RS04265
gene id: 1121451:DESAM_RS04265
uniprot id: L0R9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1121451:DESAM RS16010
gene id: 1121451:DESAM_RS16010
uniprot id: L0RGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1121451:DESAM RS15965
gene id: 1121451:DESAM_RS15965
uniprot id: L0RF68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1121451:DESAM RS03095
gene id: 1121451:DESAM_RS03095
uniprot id: L0R914
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS09310
gene id: 1121451:DESAM_RS09310
uniprot id: L0RB72
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1121451:DESAM RS07850
gene id: 1121451:DESAM_RS07850
uniprot id: L0RBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1121451:DESAM RS03660
gene id: 1121451:DESAM_RS03660
uniprot id: L0R9A8
names: Similarity
messages: Belongs to the SfsA family.

1121451:DESAM RS04680
gene id: 1121451:DESAM_RS04680
uniprot id: L0RA04
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08995
gene id: 1121451:DESAM_RS08995
uniprot id: L0RCM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1121451:DESAM RS14975
gene id: 1121451:DESAM_RS14975
uniprot id: L0RG60
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1121451:DESAM RS13855
gene id: 1121451:DESAM_RS13855
uniprot id: L0RFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1121451:DESAM RS05370
gene id: 1121451:DESAM_RS05370
uniprot id: L0RAE3
names: Similarity
messages: Belongs to the fabD family.

1121451:DESAM RS07645
gene id: 1121451:DESAM_RS07645
uniprot id: L0RBQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS16370
gene id: 1121451:DESAM_RS16370
uniprot id: L0RFG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Heterodimer of a large and a small subunit.
messages: Magnesium. Can also use manganese.

1121451:DESAM RS02455
gene id: 1121451:DESAM_RS02455
uniprot id: L0R8I8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1121451:DESAM RS14260
gene id: 1121451:DESAM_RS14260
uniprot id: L0RE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121451:DESAM RS04220
gene id: 1121451:DESAM_RS04220
uniprot id: L0R9P3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12905
gene id: 1121451:DESAM_RS12905
uniprot id: L0RDE0
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1121451:DESAM RS11650
gene id: 1121451:DESAM_RS11650
uniprot id: L0RCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1121451:DESAM RS12805
gene id: 1121451:DESAM_RS12805
uniprot id: L0REV9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS01580
gene id: 1121451:DESAM_RS01580
uniprot id: L0R826
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1121451:DESAM RS09190
gene id: 1121451:DESAM_RS09190
uniprot id: L0RCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1121451:DESAM RS03200
gene id: 1121451:DESAM_RS03200
uniprot id: L0R8Z7
names: Similarity
messages: Belongs to the ros/MucR family.

1121451:DESAM RS09385
gene id: 1121451:DESAM_RS09385
uniprot id: L0RB53
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1121451:DESAM RS01985
gene id: 1121451:DESAM_RS01985
uniprot id: L0R6V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS04175
gene id: 1121451:DESAM_RS04175
uniprot id: L0R848
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1121451:DESAM RS07470
gene id: 1121451:DESAM_RS07470
uniprot id: L0RBQ4
names: Similarity
messages: Belongs to the UPF0597 family.

1121451:DESAM RS12720
gene id: 1121451:DESAM_RS12720
uniprot id: L0RD72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS12055
gene id: 1121451:DESAM_RS12055
uniprot id: L0RCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1121451:DESAM RS01325
gene id: 1121451:DESAM_RS01325
uniprot id: L0R6G0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1121451:DESAM RS02565
gene id: 1121451:DESAM_RS02565
uniprot id: L0RAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121451:DESAM RS05145
gene id: 1121451:DESAM_RS05145
uniprot id: L0R8N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1121451:DESAM RS08300
gene id: 1121451:DESAM_RS08300
uniprot id: L0RC45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS15375
gene id: 1121451:DESAM_RS15375
uniprot id: L0REU5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1121451:DESAM RS09070
gene id: 1121451:DESAM_RS09070
uniprot id: L0REI9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1121451:DESAM RS00685
gene id: 1121451:DESAM_RS00685
uniprot id: L0R982
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121451:DESAM RS10890
gene id: 1121451:DESAM_RS10890
uniprot id: L0RC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS04180
gene id: 1121451:DESAM_RS04180
uniprot id: L0R853
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09895
gene id: 1121451:DESAM_RS09895
uniprot id: L0RD44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1121451:DESAM RS11520
gene id: 1121451:DESAM_RS11520
uniprot id: L0RE43
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1121451:DESAM RS16545
gene id: 1121451:DESAM_RS16545
uniprot id: L0RH13
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

1121451:DESAM RS12830
gene id: 1121451:DESAM_RS12830
uniprot id: L0REX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS15210
gene id: 1121451:DESAM_RS15210
uniprot id: L0RGB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1121451:DESAM RS10815
gene id: 1121451:DESAM_RS10815
uniprot id: L0RC11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121451:DESAM RS00750
gene id: 1121451:DESAM_RS00750
uniprot id: L0R7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1121451:DESAM RS15135
gene id: 1121451:DESAM_RS15135
uniprot id: L0REP3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121451:DESAM RS04395
gene id: 1121451:DESAM_RS04395
uniprot id: L0R9V9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS16375
gene id: 1121451:DESAM_RS16375
uniprot id: L0RH10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS00895
gene id: 1121451:DESAM_RS00895
uniprot id: L0R669
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121451:DESAM RS08780
gene id: 1121451:DESAM_RS08780
uniprot id: L0RAW1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS04640
gene id: 1121451:DESAM_RS04640
uniprot id: L0R9W7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121451:DESAM RS09305
gene id: 1121451:DESAM_RS09305
uniprot id: L0RB42
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1121451:DESAM RS11480
gene id: 1121451:DESAM_RS11480
uniprot id: L0RCJ2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1121451:DESAM RS11030
gene id: 1121451:DESAM_RS11030
uniprot id: L0RFM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121451:DESAM RS06585
gene id: 1121451:DESAM_RS06585
uniprot id: L0RB43
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS10410
gene id: 1121451:DESAM_RS10410
uniprot id: L0RDD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1121451:DESAM RS03120
gene id: 1121451:DESAM_RS03120
uniprot id: L0RAT2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1121451:DESAM RS02500
gene id: 1121451:DESAM_RS02500
uniprot id: L0R752
names: Similarity
messages: Belongs to the UPF0758 family.

1121451:DESAM RS03165
gene id: 1121451:DESAM_RS03165
uniprot id: L0R929
names: Similarity
messages: Belongs to the peptidase S49 family.

1121451:DESAM RS11790
gene id: 1121451:DESAM_RS11790
uniprot id: L0RCQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS07775
gene id: 1121451:DESAM_RS07775
uniprot id: L0RDN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121451:DESAM RS05105
gene id: 1121451:DESAM_RS05105
uniprot id: L0RC24
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121451:DESAM RS05985
gene id: 1121451:DESAM_RS05985
uniprot id: L0R957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS02125
gene id: 1121451:DESAM_RS02125
uniprot id: L0R6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS08535
gene id: 1121451:DESAM_RS08535
uniprot id: L0RE35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1121451:DESAM RS04770
gene id: 1121451:DESAM_RS04770
uniprot id: L0RA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1121451:DESAM RS03540
gene id: 1121451:DESAM_RS03540
uniprot id: L0RB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS10025
gene id: 1121451:DESAM_RS10025
uniprot id: L0RBH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1121451:DESAM RS10830
gene id: 1121451:DESAM_RS10830
uniprot id: L0RFH6
names: Similarity
messages: Belongs to the AOR/FOR family.

1121451:DESAM RS00625
gene id: 1121451:DESAM_RS00625
uniprot id: L0R7D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS12280
gene id: 1121451:DESAM_RS12280
uniprot id: L0REL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS05325
gene id: 1121451:DESAM_RS05325
uniprot id: L0RAD3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS01680
gene id: 1121451:DESAM_RS01680
uniprot id: L0R9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1121451:DESAM RS05135
gene id: 1121451:DESAM_RS05135
uniprot id: L0RA69
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS02290
gene id: 1121451:DESAM_RS02290
uniprot id: L0RAB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10980
gene id: 1121451:DESAM_RS10980
uniprot id: L0RDS8
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121451:DESAM RS11315
gene id: 1121451:DESAM_RS11315
uniprot id: L0RCE0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS13240
gene id: 1121451:DESAM_RS13240
uniprot id: L0RDI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15300
gene id: 1121451:DESAM_RS15300
uniprot id: L0REQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121451:DESAM RS15215
gene id: 1121451:DESAM_RS15215
uniprot id: L0RI19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1121451:DESAM RS08530
gene id: 1121451:DESAM_RS08530
uniprot id: L0RCA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121451:DESAM RS07640
gene id: 1121451:DESAM_RS07640
uniprot id: L0RDL1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121451:DESAM RS09170
gene id: 1121451:DESAM_RS09170
uniprot id: L0REK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1121451:DESAM RS09440
gene id: 1121451:DESAM_RS09440
uniprot id: L0RCV9
names: Similarity
messages: Belongs to the GSP E family.

1121451:DESAM RS16380
gene id: 1121451:DESAM_RS16380
uniprot id: L0RIT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS11455
gene id: 1121451:DESAM_RS11455
uniprot id: L0RCI9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1121451:DESAM RS04090
gene id: 1121451:DESAM_RS04090
uniprot id: L0R9M0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1121451:DESAM RS00365
gene id: 1121451:DESAM_RS00365
uniprot id: L0R778
names: Similarity
messages: Belongs to the CobH/CbiC family.

1121451:DESAM RS00220
gene id: 1121451:DESAM_RS00220
uniprot id: L0R8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1121451:DESAM RS01940
gene id: 1121451:DESAM_RS01940
uniprot id: L0R6T3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121451:DESAM RS16300
gene id: 1121451:DESAM_RS16300
uniprot id: L0RFB4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1121451:DESAM RS03485
gene id: 1121451:DESAM_RS03485
uniprot id: L0R996
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1121451:DESAM RS12205
gene id: 1121451:DESAM_RS12205
uniprot id: L0RCV3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1121451:DESAM RS06930
gene id: 1121451:DESAM_RS06930
uniprot id: L0RBA7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS06305
gene id: 1121451:DESAM_RS06305
uniprot id: L0RAZ3
names: Similarity
messages: Belongs to the GARS family.

1121451:DESAM RS01825
gene id: 1121451:DESAM_RS01825
uniprot id: L0R6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121451:DESAM RS13160
gene id: 1121451:DESAM_RS13160
uniprot id: L0RF31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1121451:DESAM RS04755
gene id: 1121451:DESAM_RS04755
uniprot id: L0R9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1121451:DESAM RS08465
gene id: 1121451:DESAM_RS08465
uniprot id: L0RE12
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1121451:DESAM RS00755
gene id: 1121451:DESAM_RS00755
uniprot id: L0R997
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS15975
gene id: 1121451:DESAM_RS15975
uniprot id: L0RGT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS09475
gene id: 1121451:DESAM_RS09475
uniprot id: L0RCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1121451:DESAM RS16510
gene id: 1121451:DESAM_RS16510
uniprot id: L0RH34
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1121451:DESAM RS04940
gene id: 1121451:DESAM_RS04940
uniprot id: L0R8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1121451:DESAM RS10305
gene id: 1121451:DESAM_RS10305
uniprot id: L0RBS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS14370
gene id: 1121451:DESAM_RS14370
uniprot id: L0RE47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121451:DESAM RS13065
gene id: 1121451:DESAM_RS13065
uniprot id: L0RDE8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121451:DESAM RS05365
gene id: 1121451:DESAM_RS05365
uniprot id: L0R8S3
names: Similarity
messages: Belongs to the peptidase C69 family.

1121451:DESAM RS04870
gene id: 1121451:DESAM_RS04870
uniprot id: L0R8H0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1121451:DESAM RS07110
gene id: 1121451:DESAM_RS07110
uniprot id: L0R9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1121451:DESAM RS14600
gene id: 1121451:DESAM_RS14600
uniprot id: L0RFV3
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS13100
gene id: 1121451:DESAM_RS13100
uniprot id: L0RF28
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121451:DESAM RS06235
gene id: 1121451:DESAM_RS06235
uniprot id: L0R9C1
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1121451:DESAM RS03450
gene id: 1121451:DESAM_RS03450
uniprot id: L0R959
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121451:DESAM RS14930
gene id: 1121451:DESAM_RS14930
uniprot id: L0RHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121451:DESAM RS06770
gene id: 1121451:DESAM_RS06770
uniprot id: L0RD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1121451:DESAM RS07590
gene id: 1121451:DESAM_RS07590
uniprot id: L0RBS7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1121451:DESAM RS06110
gene id: 1121451:DESAM_RS06110
uniprot id: L0RCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1121451:DESAM RS15265
gene id: 1121451:DESAM_RS15265
uniprot id: L0RI27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1121451:DESAM RS03935
gene id: 1121451:DESAM_RS03935
uniprot id: L0R9I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121451:DESAM RS15130
gene id: 1121451:DESAM_RS15130
uniprot id: L0REL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121451:DESAM RS13110
gene id: 1121451:DESAM_RS13110
uniprot id: L0RF21
names: Similarity
messages: Belongs to the UPF0235 family.

1121451:DESAM RS08590
gene id: 1121451:DESAM_RS08590
uniprot id: L0RAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1121451:DESAM RS09720
gene id: 1121451:DESAM_RS09720
uniprot id: L0REV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS05465
gene id: 1121451:DESAM_RS05465
uniprot id: L0RC92
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1121451:DESAM RS04110
gene id: 1121451:DESAM_RS04110
uniprot id: L0R9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121451:DESAM RS03860
gene id: 1121451:DESAM_RS03860
uniprot id: L0R7X9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1121451:DESAM RS13630
gene id: 1121451:DESAM_RS13630
uniprot id: L0RFF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS04935
gene id: 1121451:DESAM_RS04935
uniprot id: L0RA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1121451:DESAM RS14605
gene id: 1121451:DESAM_RS14605
uniprot id: L0RE96
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121451:DESAM RS04140
gene id: 1121451:DESAM_RS04140
uniprot id: L0RBJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS01990
gene id: 1121451:DESAM_RS01990
uniprot id: L0R6U2
names: Similarity
messages: Belongs to the Ahb/Nir family.

1121451:DESAM RS02845
gene id: 1121451:DESAM_RS02845
uniprot id: L0R7B3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS04430
gene id: 1121451:DESAM_RS04430
uniprot id: L0R9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1121451:DESAM RS14430
gene id: 1121451:DESAM_RS14430
uniprot id: L0RHM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1121451:DESAM RS15460
gene id: 1121451:DESAM_RS15460
uniprot id: L0RI54
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1121451:DESAM RS06755
gene id: 1121451:DESAM_RS06755
uniprot id: L0R9L8
names: Subunit
messages: Heterodimer of a large and a small subunit.

1121451:DESAM RS06205
gene id: 1121451:DESAM_RS06205
uniprot id: L0RAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1121451:DESAM RS06810
gene id: 1121451:DESAM_RS06810
uniprot id: L0RBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS16390
gene id: 1121451:DESAM_RS16390
uniprot id: L0RFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS08470
gene id: 1121451:DESAM_RS08470
uniprot id: L0RC76
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00330
gene id: 1121451:DESAM_RS00330
uniprot id: L0R792
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS15275
gene id: 1121451:DESAM_RS15275
uniprot id: L0REP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1121451:DESAM RS00435
gene id: 1121451:DESAM_RS00435
uniprot id: L0R925
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS11140
gene id: 1121451:DESAM_RS11140
uniprot id: L0RDU3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10920
gene id: 1121451:DESAM_RS10920
uniprot id: L0RFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121451:DESAM RS15050
gene id: 1121451:DESAM_RS15050
uniprot id: L0RHZ1
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1121451:DESAM RS15830
gene id: 1121451:DESAM_RS15830
uniprot id: L0RGL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1121451:DESAM RS11660
gene id: 1121451:DESAM_RS11660
uniprot id: L0RG21
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10170
gene id: 1121451:DESAM_RS10170
uniprot id: L0RF44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1121451:DESAM RS03405
gene id: 1121451:DESAM_RS03405
uniprot id: L0R7M8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1121451:DESAM RS01925
gene id: 1121451:DESAM_RS01925
uniprot id: L0RA49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121451:DESAM RS02970
gene id: 1121451:DESAM_RS02970
uniprot id: L0R7E7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121451:DESAM RS06070
gene id: 1121451:DESAM_RS06070
uniprot id: L0RAR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1121451:DESAM RS02960
gene id: 1121451:DESAM_RS02960
uniprot id: L0RAQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS15095
gene id: 1121451:DESAM_RS15095
uniprot id: L0RG85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1121451:DESAM RS02090
gene id: 1121451:DESAM_RS02090
uniprot id: L0RA79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1121451:DESAM RS12835
gene id: 1121451:DESAM_RS12835
uniprot id: L0RGN7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1121451:DESAM RS02265
gene id: 1121451:DESAM_RS02265
uniprot id: L0RAB2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS08930
gene id: 1121451:DESAM_RS08930
uniprot id: L0REG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10210
gene id: 1121451:DESAM_RS10210
uniprot id: L0RBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the pseudouridine synthase RluA family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1121451:DESAM RS15420
gene id: 1121451:DESAM_RS15420
uniprot id: L0REV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1121451:DESAM RS04295
gene id: 1121451:DESAM_RS04295
uniprot id: L0R866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1121451:DESAM RS07810
gene id: 1121451:DESAM_RS07810
uniprot id: L0RA72
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS02110
gene id: 1121451:DESAM_RS02110
uniprot id: L0RA86
names: Similarity
messages: Belongs to the class-I fumarase family.

1121451:DESAM RS14290
gene id: 1121451:DESAM_RS14290
uniprot id: L0RE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121451:DESAM RS09015
gene id: 1121451:DESAM_RS09015
uniprot id: L0RCN2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1121451:DESAM RS01590
gene id: 1121451:DESAM_RS01590
uniprot id: L0R7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS03690
gene id: 1121451:DESAM_RS03690
uniprot id: L0R7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1121451:DESAM RS03215
gene id: 1121451:DESAM_RS03215
uniprot id: L0R935
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1121451:DESAM RS11170
gene id: 1121451:DESAM_RS11170
uniprot id: L0RCA8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1121451:DESAM RS10650
gene id: 1121451:DESAM_RS10650
uniprot id: L0RFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS01535
gene id: 1121451:DESAM_RS01535
uniprot id: L0R815
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1121451:DESAM RS03545
gene id: 1121451:DESAM_RS03545
uniprot id: L0R981
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121451:DESAM RS06200
gene id: 1121451:DESAM_RS06200
uniprot id: L0RCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1121451:DESAM RS07005
gene id: 1121451:DESAM_RS07005
uniprot id: L0R9U3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1121451:DESAM RS10205
gene id: 1121451:DESAM_RS10205
uniprot id: L0RBL8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS06980
gene id: 1121451:DESAM_RS06980
uniprot id: L0RBB8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS15090
gene id: 1121451:DESAM_RS15090
uniprot id: L0REN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS08855
gene id: 1121451:DESAM_RS08855
uniprot id: L0REE9
names: Similarity
messages: Belongs to the RemA family.

1121451:DESAM RS14555
gene id: 1121451:DESAM_RS14555
uniprot id: L0RE86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1121451:DESAM RS08200
gene id: 1121451:DESAM_RS08200
uniprot id: L0RAI7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1121451:DESAM RS11845
gene id: 1121451:DESAM_RS11845
uniprot id: L0REC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121451:DESAM RS16050
gene id: 1121451:DESAM_RS16050
uniprot id: L0RFB0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS07475
gene id: 1121451:DESAM_RS07475
uniprot id: L0RDH9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1121451:DESAM RS15715
gene id: 1121451:DESAM_RS15715
uniprot id: L0RGJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS16025
gene id: 1121451:DESAM_RS16025
uniprot id: L0RFA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12725
gene id: 1121451:DESAM_RS12725
uniprot id: L0RD99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS05535
gene id: 1121451:DESAM_RS05535
uniprot id: L0RCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1121451:DESAM RS11225
gene id: 1121451:DESAM_RS11225
uniprot id: L0RCF1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS17065
gene id: 1121451:DESAM_RS17065
uniprot id: L0R7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS14015
gene id: 1121451:DESAM_RS14015
uniprot id: L0RFJ9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1121451:DESAM RS09045
gene id: 1121451:DESAM_RS09045
uniprot id: L0REI5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS10600
gene id: 1121451:DESAM_RS10600
uniprot id: L0RDJ2
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1121451:DESAM RS05760
gene id: 1121451:DESAM_RS05760
uniprot id: L0RAK0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121451:DESAM RS06875
gene id: 1121451:DESAM_RS06875
uniprot id: L0R9P1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1121451:DESAM RS04170
gene id: 1121451:DESAM_RS04170
uniprot id: L0R9N5
names: Similarity
messages: Belongs to the FeoA family.

1121451:DESAM RS12505
gene id: 1121451:DESAM_RS12505
uniprot id: L0REP4
names: Similarity
messages: Belongs to the PhoH family.

1121451:DESAM RS00890
gene id: 1121451:DESAM_RS00890
uniprot id: L0R7J2
names: Similarity
messages: Belongs to the peptidase S16 family.

1121451:DESAM RS06220
gene id: 1121451:DESAM_RS06220
uniprot id: L0RAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121451:DESAM RS06545
gene id: 1121451:DESAM_RS06545
uniprot id: L0R9K3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1121451:DESAM RS04900
gene id: 1121451:DESAM_RS04900
uniprot id: L0RA50
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1121451:DESAM RS15140
gene id: 1121451:DESAM_RS15140
uniprot id: L0RG95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS10710
gene id: 1121451:DESAM_RS10710
uniprot id: L0RDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1121451:DESAM RS00725
gene id: 1121451:DESAM_RS00725
uniprot id: L0R7I1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121451:DESAM RS09620
gene id: 1121451:DESAM_RS09620
uniprot id: L0RBD0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1121451:DESAM RS02275
gene id: 1121451:DESAM_RS02275
uniprot id: L0R704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS09085
gene id: 1121451:DESAM_RS09085
uniprot id: L0RCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121451:DESAM RS14320
gene id: 1121451:DESAM_RS14320
uniprot id: L0RFS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121451:DESAM RS10480
gene id: 1121451:DESAM_RS10480
uniprot id: L0RBT4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121451:DESAM RS10895
gene id: 1121451:DESAM_RS10895
uniprot id: L0RDR0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121451:DESAM RS07545
gene id: 1121451:DESAM_RS07545
uniprot id: L0RDJ3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Homodimer.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-820 that is involved in catalysis.

1121451:DESAM RS07455
gene id: 1121451:DESAM_RS07455
uniprot id: L0RBL0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS12785
gene id: 1121451:DESAM_RS12785
uniprot id: L0RGN0
names: Similarity
messages: Belongs to the SlyX family.

1121451:DESAM RS15765
gene id: 1121451:DESAM_RS15765
uniprot id: L0RF05
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121451:DESAM RS14990
gene id: 1121451:DESAM_RS14990
uniprot id: L0REH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121451:DESAM RS05510
gene id: 1121451:DESAM_RS05510
uniprot id: L0RCA0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS10165
gene id: 1121451:DESAM_RS10165
uniprot id: L0RDA2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1121451:DESAM RS14305
gene id: 1121451:DESAM_RS14305
uniprot id: L0RFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1121451:DESAM RS15435
gene id: 1121451:DESAM_RS15435
uniprot id: L0RGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1121451:DESAM RS13875
gene id: 1121451:DESAM_RS13875
uniprot id: L0RDZ1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS02980
gene id: 1121451:DESAM_RS02980
uniprot id: L0R8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121451:DESAM RS11890
gene id: 1121451:DESAM_RS11890
uniprot id: L0RED4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS05540
gene id: 1121451:DESAM_RS05540
uniprot id: L0RAF6
names: Similarity
messages: Belongs to the GSP E family.

1121451:DESAM RS08960
gene id: 1121451:DESAM_RS08960
uniprot id: L0RCJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1121451:DESAM RS06215
gene id: 1121451:DESAM_RS06215
uniprot id: L0R9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1121451:DESAM RS02475
gene id: 1121451:DESAM_RS02475
uniprot id: L0R8J3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1121451:DESAM RS07030
gene id: 1121451:DESAM_RS07030
uniprot id: L0RBH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS05665
gene id: 1121451:DESAM_RS05665
uniprot id: L0R8Y4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS04520
gene id: 1121451:DESAM_RS04520
uniprot id: L0R898
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121451:DESAM RS08745
gene id: 1121451:DESAM_RS08745
uniprot id: L0RE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS13345
gene id: 1121451:DESAM_RS13345
uniprot id: L0RGZ8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS07390
gene id: 1121451:DESAM_RS07390
uniprot id: L0R9Y9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121451:DESAM RS10595
gene id: 1121451:DESAM_RS10595
uniprot id: L0RBY9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121451:DESAM RS13385
gene id: 1121451:DESAM_RS13385
uniprot id: L0RF79
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1121451:DESAM RS03085
gene id: 1121451:DESAM_RS03085
uniprot id: L0R7G7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121451:DESAM RS14585
gene id: 1121451:DESAM_RS14585
uniprot id: L0REC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS10285
gene id: 1121451:DESAM_RS10285
uniprot id: L0RDC7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121451:DESAM RS13900
gene id: 1121451:DESAM_RS13900
uniprot id: L0RFK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS04800
gene id: 1121451:DESAM_RS04800
uniprot id: L0RA01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1121451:DESAM RS03600
gene id: 1121451:DESAM_RS03600
uniprot id: L0R7S4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1121451:DESAM RS07415
gene id: 1121451:DESAM_RS07415
uniprot id: L0R9Z3
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121451:DESAM RS05785
gene id: 1121451:DESAM_RS05785
uniprot id: L0RAK5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1121451:DESAM RS12485
gene id: 1121451:DESAM_RS12485
uniprot id: L0REN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1121451:DESAM RS08860
gene id: 1121451:DESAM_RS08860
uniprot id: L0RCH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1121451:DESAM RS10810
gene id: 1121451:DESAM_RS10810
uniprot id: L0RDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1121451:DESAM RS01720
gene id: 1121451:DESAM_RS01720
uniprot id: L0R852
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1121451:DESAM RS05895
gene id: 1121451:DESAM_RS05895
uniprot id: L0RAN0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1121451:DESAM RS14715
gene id: 1121451:DESAM_RS14715
uniprot id: L0RG06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121451:DESAM RS04850
gene id: 1121451:DESAM_RS04850
uniprot id: L0R8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1121451:DESAM RS13845
gene id: 1121451:DESAM_RS13845
uniprot id: L0RDV6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121451:DESAM RS03730
gene id: 1121451:DESAM_RS03730
uniprot id: L0RB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS11615
gene id: 1121451:DESAM_RS11615
uniprot id: L0RG12
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1121451:DESAM RS11465
gene id: 1121451:DESAM_RS11465
uniprot id: L0RFY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1121451:DESAM RS06785
gene id: 1121451:DESAM_RS06785
uniprot id: L0R9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS06310
gene id: 1121451:DESAM_RS06310
uniprot id: L0RCS1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1121451:DESAM RS12140
gene id: 1121451:DESAM_RS12140
uniprot id: L0RCW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1121451:DESAM RS13685
gene id: 1121451:DESAM_RS13685
uniprot id: L0RFG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12825
gene id: 1121451:DESAM_RS12825
uniprot id: L0RDC0
names: Similarity
messages: Belongs to the catalase family.

1121451:DESAM RS08460
gene id: 1121451:DESAM_RS08460
uniprot id: L0RC95
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS12215
gene id: 1121451:DESAM_RS12215
uniprot id: L0REJ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1121451:DESAM RS12790
gene id: 1121451:DESAM_RS12790
uniprot id: L0REV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS05320
gene id: 1121451:DESAM_RS05320
uniprot id: L0R8R2
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS16070
gene id: 1121451:DESAM_RS16070
uniprot id: L0RF81
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1121451:DESAM RS08625
gene id: 1121451:DESAM_RS08625
uniprot id: L0RCC4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121451:DESAM RS12940
gene id: 1121451:DESAM_RS12940
uniprot id: L0RGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121451:DESAM RS02420
gene id: 1121451:DESAM_RS02420
uniprot id: L0R8M3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1121451:DESAM RS16185
gene id: 1121451:DESAM_RS16185
uniprot id: L0RGT6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1121451:DESAM RS03455
gene id: 1121451:DESAM_RS03455
uniprot id: L0R7P9
names: Similarity
messages: Belongs to the UPF0047 family.

1121451:DESAM RS07820
gene id: 1121451:DESAM_RS07820
uniprot id: L0RDP2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1121451:DESAM RS04035
gene id: 1121451:DESAM_RS04035
uniprot id: L0RBD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS01435
gene id: 1121451:DESAM_RS01435
uniprot id: L0R7W4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121451:DESAM RS15675
gene id: 1121451:DESAM_RS15675
uniprot id: L0RF13
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1121451:DESAM RS00745
gene id: 1121451:DESAM_RS00745
uniprot id: L0R642
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1121451:DESAM RS13195
gene id: 1121451:DESAM_RS13195
uniprot id: L0RDK0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS11820
gene id: 1121451:DESAM_RS11820
uniprot id: L0REC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1121451:DESAM RS15075
gene id: 1121451:DESAM_RS15075
uniprot id: L0RHZ6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121451:DESAM RS11670
gene id: 1121451:DESAM_RS11670
uniprot id: L0RCJ1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS06165
gene id: 1121451:DESAM_RS06165
uniprot id: L0R9A4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1121451:DESAM RS15955
gene id: 1121451:DESAM_RS15955
uniprot id: L0RIK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1121451:DESAM RS00240
gene id: 1121451:DESAM_RS00240
uniprot id: L0R771
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1121451:DESAM RS06210
gene id: 1121451:DESAM_RS06210
uniprot id: L0R9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1121451:DESAM RS05065
gene id: 1121451:DESAM_RS05065
uniprot id: L0RA52
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS05125
gene id: 1121451:DESAM_RS05125
uniprot id: L0RA92
names: Similarity
messages: Belongs to the peptidase S16 family.

1121451:DESAM RS11300
gene id: 1121451:DESAM_RS11300
uniprot id: L0RE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1121451:DESAM RS11880
gene id: 1121451:DESAM_RS11880
uniprot id: L0RCN5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1121451:DESAM RS02555
gene id: 1121451:DESAM_RS02555
uniprot id: L0R743
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121451:DESAM RS13835
gene id: 1121451:DESAM_RS13835
uniprot id: L0RHC1
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1121451:DESAM RS15555
gene id: 1121451:DESAM_RS15555
uniprot id: L0RGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1121451:DESAM RS02880
gene id: 1121451:DESAM_RS02880
uniprot id: L0R8T1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS06945
gene id: 1121451:DESAM_RS06945
uniprot id: L0RBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS06055
gene id: 1121451:DESAM_RS06055
uniprot id: L0RAR3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS05955
gene id: 1121451:DESAM_RS05955
uniprot id: L0R958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS13725
gene id: 1121451:DESAM_RS13725
uniprot id: L0RDU0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1121451:DESAM RS08720
gene id: 1121451:DESAM_RS08720
uniprot id: L0RE88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1121451:DESAM RS10185
gene id: 1121451:DESAM_RS10185
uniprot id: L0RBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121451:DESAM RS15055
gene id: 1121451:DESAM_RS15055
uniprot id: L0RG54
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1121451:DESAM RS00695
gene id: 1121451:DESAM_RS00695
uniprot id: L0R625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1121451:DESAM RS00195
gene id: 1121451:DESAM_RS00195
uniprot id: L0R741
names: Similarity
messages: Belongs to the pyruvate kinase family.

1121451:DESAM RS01915
gene id: 1121451:DESAM_RS01915
uniprot id: L0R6T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121451:DESAM RS07150
gene id: 1121451:DESAM_RS07150
uniprot id: L0RBF4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1121451:DESAM RS15175
gene id: 1121451:DESAM_RS15175
uniprot id: L0REM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1121451:DESAM RS14765
gene id: 1121451:DESAM_RS14765
uniprot id: L0RG16
names: Subcellular Location Annotation
messages: Cell inner membrane

1121451:DESAM RS15240
gene id: 1121451:DESAM_RS15240
uniprot id: L0RI23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS04560
gene id: 1121451:DESAM_RS04560
uniprot id: L0RBS0
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS12190
gene id: 1121451:DESAM_RS12190
uniprot id: L0REJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1121451:DESAM RS03575
gene id: 1121451:DESAM_RS03575
uniprot id: L0R7R7
names: Subcellular Location Annotation
messages: Cytoplasm

1121451:DESAM RS16385
gene id: 1121451:DESAM_RS16385
uniprot id: L0RGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121451:DESAM RS10705
gene id: 1121451:DESAM_RS10705
uniprot id: L0RDL7
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS02610
gene id: 1121451:DESAM_RS02610
uniprot id: L0R775
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1121451:DESAM RS14070
gene id: 1121451:DESAM_RS14070
uniprot id: L0RDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS03280
gene id: 1121451:DESAM_RS03280
uniprot id: L0R7K3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121451:DESAM RS11430
gene id: 1121451:DESAM_RS11430
uniprot id: L0RCI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1121451:DESAM RS11390
gene id: 1121451:DESAM_RS11390
uniprot id: L0RFX5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1121451:DESAM RS11910
gene id: 1121451:DESAM_RS11910
uniprot id: L0RCS6
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08840
gene id: 1121451:DESAM_RS08840
uniprot id: L0RCH1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1121451:DESAM RS15020
gene id: 1121451:DESAM_RS15020
uniprot id: L0RG70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS09650
gene id: 1121451:DESAM_RS09650
uniprot id: L0REU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1121451:DESAM RS03670
gene id: 1121451:DESAM_RS03670
uniprot id: L0R7T9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS01665
gene id: 1121451:DESAM_RS01665
uniprot id: L0R6M8
names: Similarity
messages: Belongs to the citrate synthase family.

1121451:DESAM RS09875
gene id: 1121451:DESAM_RS09875
uniprot id: L0RD39
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08215
gene id: 1121451:DESAM_RS08215
uniprot id: L0RC25
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS12260
gene id: 1121451:DESAM_RS12260
uniprot id: L0RGD2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1121451:DESAM RS06010
gene id: 1121451:DESAM_RS06010
uniprot id: L0R962
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS00845
gene id: 1121451:DESAM_RS00845
uniprot id: L0R659
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS12840
gene id: 1121451:DESAM_RS12840
uniprot id: L0REW4
names: Similarity
messages: Belongs to the peptidase M18 family.

1121451:DESAM RS12230
gene id: 1121451:DESAM_RS12230
uniprot id: L0RCY5
names: Similarity
messages: Belongs to the peptidase A31 family.

1121451:DESAM RS07175
gene id: 1121451:DESAM_RS07175
uniprot id: L0RBF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1121451:DESAM RS00770
gene id: 1121451:DESAM_RS00770
uniprot id: L0R646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1121451:DESAM RS01770
gene id: 1121451:DESAM_RS01770
uniprot id: L0R833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1121451:DESAM RS16035
gene id: 1121451:DESAM_RS16035
uniprot id: L0RGU0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS01905
gene id: 1121451:DESAM_RS01905
uniprot id: L0R884
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121451:DESAM RS12925
gene id: 1121451:DESAM_RS12925
uniprot id: L0RDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1121451:DESAM RS10355
gene id: 1121451:DESAM_RS10355
uniprot id: L0RBT8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121451:DESAM RS10755
gene id: 1121451:DESAM_RS10755
uniprot id: L0RFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1121451:DESAM RS05175
gene id: 1121451:DESAM_RS05175
uniprot id: L0RAA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1121451:DESAM RS08190
gene id: 1121451:DESAM_RS08190
uniprot id: L0RC18
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1121451:DESAM RS06115
gene id: 1121451:DESAM_RS06115
uniprot id: L0RAS8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1121451:DESAM RS00675
gene id: 1121451:DESAM_RS00675
uniprot id: L0R620
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121451:DESAM RS05830
gene id: 1121451:DESAM_RS05830
uniprot id: L0RCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS00560
gene id: 1121451:DESAM_RS00560
uniprot id: L0R5Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1121451:DESAM RS07565
gene id: 1121451:DESAM_RS07565
uniprot id: L0RBS3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1121451:DESAM RS07485
gene id: 1121451:DESAM_RS07485
uniprot id: L0RA06
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1121451:DESAM RS15510
gene id: 1121451:DESAM_RS15510
uniprot id: L0RGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15170
gene id: 1121451:DESAM_RS15170
uniprot id: L0RG81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1121451:DESAM RS02560
gene id: 1121451:DESAM_RS02560
uniprot id: L0R8Q6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1121451:DESAM RS11605
gene id: 1121451:DESAM_RS11605
uniprot id: L0RCL4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121451:DESAM RS10505
gene id: 1121451:DESAM_RS10505
uniprot id: L0RBT9
names: Subcellular Location Annotation
messages: Cytoplasm

1121451:DESAM RS02220
gene id: 1121451:DESAM_RS02220
uniprot id: L0R8E3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1121451:DESAM RS02485
gene id: 1121451:DESAM_RS02485
uniprot id: L0R8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1121451:DESAM RS02445
gene id: 1121451:DESAM_RS02445
uniprot id: L0R8M9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1121451:DESAM RS03920
gene id: 1121451:DESAM_RS03920
uniprot id: L0R9G6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS13430
gene id: 1121451:DESAM_RS13430
uniprot id: L0RH20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1121451:DESAM RS13720
gene id: 1121451:DESAM_RS13720
uniprot id: L0RFE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1121451:DESAM RS14920
gene id: 1121451:DESAM_RS14920
uniprot id: L0REJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1121451:DESAM RS06410
gene id: 1121451:DESAM_RS06410
uniprot id: L0RCU6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1121451:DESAM RS07625
gene id: 1121451:DESAM_RS07625
uniprot id: L0RBP8
names: Similarity
messages: Belongs to the EutP/PduV family.

1121451:DESAM RS02380
gene id: 1121451:DESAM_RS02380
uniprot id: L0RAD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS14420
gene id: 1121451:DESAM_RS14420
uniprot id: L0RE95
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1121451:DESAM RS06160
gene id: 1121451:DESAM_RS06160
uniprot id: L0R999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1121451:DESAM RS16655
gene id: 1121451:DESAM_RS16655
uniprot id: L0RE45
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09265
gene id: 1121451:DESAM_RS09265
uniprot id: L0RCS9
names: Subcellular Location Annotation
messages: Secreted

1121451:DESAM RS13020
gene id: 1121451:DESAM_RS13020
uniprot id: L0RDG6
names: Similarity
messages: Belongs to the peptidase S24 family.

1121451:DESAM RS10840
gene id: 1121451:DESAM_RS10840
uniprot id: L0RC17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1121451:DESAM RS00305
gene id: 1121451:DESAM_RS00305
uniprot id: L0R786
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1121451:DESAM RS06000
gene id: 1121451:DESAM_RS06000
uniprot id: L0RCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1121451:DESAM RS13905
gene id: 1121451:DESAM_RS13905
uniprot id: L0RHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1121451:DESAM RS16415
gene id: 1121451:DESAM_RS16415
uniprot id: L0RH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS08990
gene id: 1121451:DESAM_RS08990
uniprot id: L0RB19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1121451:DESAM RS10850
gene id: 1121451:DESAM_RS10850
uniprot id: L0RDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1121451:DESAM RS02405
gene id: 1121451:DESAM_RS02405
uniprot id: L0R8I0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1121451:DESAM RS03870
gene id: 1121451:DESAM_RS03870
uniprot id: L0R9H1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1121451:DESAM RS05395
gene id: 1121451:DESAM_RS05395
uniprot id: L0RAE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121451:DESAM RS04690
gene id: 1121451:DESAM_RS04690
uniprot id: L0R9X6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS08880
gene id: 1121451:DESAM_RS08880
uniprot id: L0REF4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS04790
gene id: 1121451:DESAM_RS04790
uniprot id: L0RA25
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121451:DESAM RS11855
gene id: 1121451:DESAM_RS11855
uniprot id: L0REA9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1121451:DESAM RS11990
gene id: 1121451:DESAM_RS11990
uniprot id: L0REF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1121451:DESAM RS11740
gene id: 1121451:DESAM_RS11740
uniprot id: L0RCP3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1121451:DESAM RS15180
gene id: 1121451:DESAM_RS15180
uniprot id: L0REQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS15190
gene id: 1121451:DESAM_RS15190
uniprot id: L0RI15
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1121451:DESAM RS09870
gene id: 1121451:DESAM_RS09870
uniprot id: L0RBH7
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Heterodimer of a large and a small subunit.

1121451:DESAM RS12150
gene id: 1121451:DESAM_RS12150
uniprot id: L0REG1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121451:DESAM RS07140
gene id: 1121451:DESAM_RS07140
uniprot id: L0RBJ1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS15805
gene id: 1121451:DESAM_RS15805
uniprot id: L0RGL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1121451:DESAM RS08360
gene id: 1121451:DESAM_RS08360
uniprot id: L0RC82
names: Similarity
messages: Belongs to the PhoU family.

1121451:DESAM RS00350
gene id: 1121451:DESAM_RS00350
uniprot id: L0R5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15060
gene id: 1121451:DESAM_RS15060
uniprot id: L0REJ2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1121451:DESAM RS07880
gene id: 1121451:DESAM_RS07880
uniprot id: L0RBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS14335
gene id: 1121451:DESAM_RS14335
uniprot id: L0RE75
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1121451:DESAM RS08895
gene id: 1121451:DESAM_RS08895
uniprot id: L0RB01
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1121451:DESAM RS13735
gene id: 1121451:DESAM_RS13735
uniprot id: L0RFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1121451:DESAM RS08865
gene id: 1121451:DESAM_RS08865
uniprot id: L0RAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1121451:DESAM RS05520
gene id: 1121451:DESAM_RS05520
uniprot id: L0R8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1121451:DESAM RS06650
gene id: 1121451:DESAM_RS06650
uniprot id: L0RD29
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS03270
gene id: 1121451:DESAM_RS03270
uniprot id: L0R7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121451:DESAM RS01685
gene id: 1121451:DESAM_RS01685
uniprot id: L0R6N4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1121451:DESAM RS04675
gene id: 1121451:DESAM_RS04675
uniprot id: L0R8D7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1121451:DESAM RS10915
gene id: 1121451:DESAM_RS10915
uniprot id: L0RDR4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS00425
gene id: 1121451:DESAM_RS00425
uniprot id: L0R5Y0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1121451:DESAM RS11695
gene id: 1121451:DESAM_RS11695
uniprot id: L0RCN4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1121451:DESAM RS09775
gene id: 1121451:DESAM_RS09775
uniprot id: L0RBF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS01525
gene id: 1121451:DESAM_RS01525
uniprot id: L0R6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121451:DESAM RS12765
gene id: 1121451:DESAM_RS12765
uniprot id: L0REU9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS04705
gene id: 1121451:DESAM_RS04705
uniprot id: L0RBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1121451:DESAM RS11945
gene id: 1121451:DESAM_RS11945
uniprot id: L0RG74
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1121451:DESAM RS12175
gene id: 1121451:DESAM_RS12175
uniprot id: L0REG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1121451:DESAM RS03130
gene id: 1121451:DESAM_RS03130
uniprot id: L0R7H7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS03945
gene id: 1121451:DESAM_RS03945
uniprot id: L0R9H0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS13070
gene id: 1121451:DESAM_RS13070
uniprot id: L0RDH5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1121451:DESAM RS00855
gene id: 1121451:DESAM_RS00855
uniprot id: L0R7L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1121451:DESAM RS00470
gene id: 1121451:DESAM_RS00470
uniprot id: L0R7C3
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121451:DESAM RS06095
gene id: 1121451:DESAM_RS06095
uniprot id: L0RAS3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121451:DESAM RS03175
gene id: 1121451:DESAM_RS03175
uniprot id: L0R8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121451:DESAM RS15155
gene id: 1121451:DESAM_RS15155
uniprot id: L0REL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1121451:DESAM RS09930
gene id: 1121451:DESAM_RS09930
uniprot id: L0RD26
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121451:DESAM RS09675
gene id: 1121451:DESAM_RS09675
uniprot id: L0REU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1121451:DESAM RS12545
gene id: 1121451:DESAM_RS12545
uniprot id: L0RER7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121451:DESAM RS03255
gene id: 1121451:DESAM_RS03255
uniprot id: L0RAV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1121451:DESAM RS14175
gene id: 1121451:DESAM_RS14175
uniprot id: L0RHH8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1121451:DESAM RS02360
gene id: 1121451:DESAM_RS02360
uniprot id: L0RAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121451:DESAM RS01955
gene id: 1121451:DESAM_RS01955
uniprot id: L0R893
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1121451:DESAM RS07435
gene id: 1121451:DESAM_RS07435
uniprot id: L0RBK4
names: Similarity
messages: Belongs to the HdrA family.

1121451:DESAM RS03615
gene id: 1121451:DESAM_RS03615
uniprot id: L0R998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1121451:DESAM RS02310
gene id: 1121451:DESAM_RS02310
uniprot id: L0R8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1121451:DESAM RS09215
gene id: 1121451:DESAM_RS09215
uniprot id: L0RCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1121451:DESAM RS10530
gene id: 1121451:DESAM_RS10530
uniprot id: L0RBX7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1121451:DESAM RS10075
gene id: 1121451:DESAM_RS10075
uniprot id: L0RBM0
names: Similarity
messages: Belongs to the VgrG protein family.

1121451:DESAM RS05185
gene id: 1121451:DESAM_RS05185
uniprot id: L0RA80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1121451:DESAM RS00295
gene id: 1121451:DESAM_RS00295
uniprot id: L0R761
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS13680
gene id: 1121451:DESAM_RS13680
uniprot id: L0RDW1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1121451:DESAM RS08695
gene id: 1121451:DESAM_RS08695
uniprot id: L0RE81
names: Similarity
messages: Belongs to the MEMO1 family.

1121451:DESAM RS15575
gene id: 1121451:DESAM_RS15575
uniprot id: L0REW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1121451:DESAM RS03285
gene id: 1121451:DESAM_RS03285
uniprot id: L0R955
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1121451:DESAM RS15780
gene id: 1121451:DESAM_RS15780
uniprot id: L0RID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121451:DESAM RS00245
gene id: 1121451:DESAM_RS00245
uniprot id: L0R8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1121451:DESAM RS03005
gene id: 1121451:DESAM_RS03005
uniprot id: L0R8Z9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS09640
gene id: 1121451:DESAM_RS09640
uniprot id: L0RBA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS02115
gene id: 1121451:DESAM_RS02115
uniprot id: L0R8C5
names: Similarity
messages: Belongs to the class-I fumarase family.

1121451:DESAM RS09415
gene id: 1121451:DESAM_RS09415
uniprot id: L0RCV6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1121451:DESAM RS11640
gene id: 1121451:DESAM_RS11640
uniprot id: L0RE67
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12950
gene id: 1121451:DESAM_RS12950
uniprot id: L0RDE9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1121451:DESAM RS09115
gene id: 1121451:DESAM_RS09115
uniprot id: L0REJ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS07995
gene id: 1121451:DESAM_RS07995
uniprot id: L0RC05
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121451:DESAM RS15445
gene id: 1121451:DESAM_RS15445
uniprot id: L0REW1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1121451:DESAM RS11050
gene id: 1121451:DESAM_RS11050
uniprot id: L0RDU5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1121451:DESAM RS13010
gene id: 1121451:DESAM_RS13010
uniprot id: L0RF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1121451:DESAM RS10715
gene id: 1121451:DESAM_RS10715
uniprot id: L0RBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1121451:DESAM RS01945
gene id: 1121451:DESAM_RS01945
uniprot id: L0R8D0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1121451:DESAM RS07065
gene id: 1121451:DESAM_RS07065
uniprot id: L0R9V7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS03030
gene id: 1121451:DESAM_RS03030
uniprot id: L0R7F0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1121451:DESAM RS13700
gene id: 1121451:DESAM_RS13700
uniprot id: L0RDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121451:DESAM RS02285
gene id: 1121451:DESAM_RS02285
uniprot id: L0R8J4
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00300
gene id: 1121451:DESAM_RS00300
uniprot id: L0R5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1121451:DESAM RS01870
gene id: 1121451:DESAM_RS01870
uniprot id: L0R874
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1121451:DESAM RS02120
gene id: 1121451:DESAM_RS02120
uniprot id: L0R6X5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1121451:DESAM RS03890
gene id: 1121451:DESAM_RS03890
uniprot id: L0R9H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1121451:DESAM RS14870
gene id: 1121451:DESAM_RS14870
uniprot id: L0REF0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS05800
gene id: 1121451:DESAM_RS05800
uniprot id: L0RAN4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1121451:DESAM RS03765
gene id: 1121451:DESAM_RS03765
uniprot id: L0R7W0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121451:DESAM RS11545
gene id: 1121451:DESAM_RS11545
uniprot id: L0RE48
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121451:DESAM RS09925
gene id: 1121451:DESAM_RS09925
uniprot id: L0REZ4
names: Similarity
messages: Belongs to the UPF0178 family.

1121451:DESAM RS11310
gene id: 1121451:DESAM_RS11310
uniprot id: L0RDZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS01805
gene id: 1121451:DESAM_RS01805
uniprot id: L0R6R5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1121451:DESAM RS01995
gene id: 1121451:DESAM_RS01995
uniprot id: L0R8D9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1121451:DESAM RS11735
gene id: 1121451:DESAM_RS11735
uniprot id: L0RCK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1121451:DESAM RS02045
gene id: 1121451:DESAM_RS02045
uniprot id: L0R8B2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121451:DESAM RS08810
gene id: 1121451:DESAM_RS08810
uniprot id: L0REC5
names: Similarity
messages: Belongs to the IMPACT family.

1121451:DESAM RS09960
gene id: 1121451:DESAM_RS09960
uniprot id: L0RBJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1121451:DESAM RS00445
gene id: 1121451:DESAM_RS00445
uniprot id: L0R5X0
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1121451:DESAM RS02075
gene id: 1121451:DESAM_RS02075
uniprot id: L0R6W6
names: Function
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1121451:DESAM RS11950
gene id: 1121451:DESAM_RS11950
uniprot id: L0REC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1121451:DESAM RS14325
gene id: 1121451:DESAM_RS14325
uniprot id: L0RHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1121451:DESAM RS15145
gene id: 1121451:DESAM_RS15145
uniprot id: L0RI07
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1121451:DESAM RS12050
gene id: 1121451:DESAM_RS12050
uniprot id: L0REE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS10260
gene id: 1121451:DESAM_RS10260
uniprot id: L0RDC3
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09175
gene id: 1121451:DESAM_RS09175
uniprot id: L0RCN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1121451:DESAM RS03560
gene id: 1121451:DESAM_RS03560
uniprot id: L0R9B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS15940
gene id: 1121451:DESAM_RS15940
uniprot id: L0RGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1121451:DESAM RS11985
gene id: 1121451:DESAM_RS11985
uniprot id: L0RCU0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1121451:DESAM RS07210
gene id: 1121451:DESAM_RS07210
uniprot id: L0RDD5
names: Similarity
messages: Belongs to the PhoH family.

1121451:DESAM RS04590
gene id: 1121451:DESAM_RS04590
uniprot id: L0R9V8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1121451:DESAM RS10960
gene id: 1121451:DESAM_RS10960
uniprot id: L0RFK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS10155
gene id: 1121451:DESAM_RS10155
uniprot id: L0RBK8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1121451:DESAM RS09315
gene id: 1121451:DESAM_RS09315
uniprot id: L0REN2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1121451:DESAM RS06965
gene id: 1121451:DESAM_RS06965
uniprot id: L0R9T3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

1121451:DESAM RS00455
gene id: 1121451:DESAM_RS00455
uniprot id: L0R931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1121451:DESAM RS14645
gene id: 1121451:DESAM_RS14645
uniprot id: L0REA5
names: Similarity
messages: Belongs to the UPF0234 family.

1121451:DESAM RS15080
gene id: 1121451:DESAM_RS15080
uniprot id: L0RG62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121451:DESAM RS13940
gene id: 1121451:DESAM_RS13940
uniprot id: L0RFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1121451:DESAM RS10265
gene id: 1121451:DESAM_RS10265
uniprot id: L0RF59
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

1121451:DESAM RS16125
gene id: 1121451:DESAM_RS16125
uniprot id: L0RFC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1121451:DESAM RS06335
gene id: 1121451:DESAM_RS06335
uniprot id: L0RCS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS14805
gene id: 1121451:DESAM_RS14805
uniprot id: L0REH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1121451:DESAM RS15990
gene id: 1121451:DESAM_RS15990
uniprot id: L0RF71
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS10175
gene id: 1121451:DESAM_RS10175
uniprot id: L0RD81
names: Similarity
messages: Belongs to the peptidase M29 family.

1121451:DESAM RS06290
gene id: 1121451:DESAM_RS06290
uniprot id: L0RAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS10845
gene id: 1121451:DESAM_RS10845
uniprot id: L0RC46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1121451:DESAM RS03705
gene id: 1121451:DESAM_RS03705
uniprot id: L0RB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1121451:DESAM RS13540
gene id: 1121451:DESAM_RS13540
uniprot id: L0RDR7
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS00410
gene id: 1121451:DESAM_RS00410
uniprot id: L0R920
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1121451:DESAM RS04970
gene id: 1121451:DESAM_RS04970
uniprot id: L0R8J5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12335
gene id: 1121451:DESAM_RS12335
uniprot id: L0RGE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1121451:DESAM RS15195
gene id: 1121451:DESAM_RS15195
uniprot id: L0RG87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1121451:DESAM RS01425
gene id: 1121451:DESAM_RS01425
uniprot id: L0R7Z1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1121451:DESAM RS07310
gene id: 1121451:DESAM_RS07310
uniprot id: L0RBL9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1121451:DESAM RS06375
gene id: 1121451:DESAM_RS06375
uniprot id: L0R9F1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1121451:DESAM RS12700
gene id: 1121451:DESAM_RS12700
uniprot id: L0RD66
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1121451:DESAM RS07615
gene id: 1121451:DESAM_RS07615
uniprot id: L0RBT2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1121451:DESAM RS16065
gene id: 1121451:DESAM_RS16065
uniprot id: L0RGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1121451:DESAM RS15030
gene id: 1121451:DESAM_RS15030
uniprot id: L0REI8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1121451:DESAM RS11905
gene id: 1121451:DESAM_RS11905
uniprot id: L0RCP0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1121451:DESAM RS06385
gene id: 1121451:DESAM_RS06385
uniprot id: L0RCU1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121451:DESAM RS00230
gene id: 1121451:DESAM_RS00230
uniprot id: L0R5S8
names: Subcellular Location Annotation
messages: Cell outer membrane

1121451:DESAM RS08195
gene id: 1121451:DESAM_RS08195
uniprot id: L0RAG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1121451:DESAM RS09140
gene id: 1121451:DESAM_RS09140
uniprot id: L0REK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS04635
gene id: 1121451:DESAM_RS04635
uniprot id: L0RBT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS04075
gene id: 1121451:DESAM_RS04075
uniprot id: L0R9L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1121451:DESAM RS08515
gene id: 1121451:DESAM_RS08515
uniprot id: L0RC86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12360
gene id: 1121451:DESAM_RS12360
uniprot id: L0RGF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS08230
gene id: 1121451:DESAM_RS08230
uniprot id: L0RDW8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1121451:DESAM RS16895
gene id: 1121451:DESAM_RS16895
uniprot id: L0RI11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1121451:DESAM RS12210
gene id: 1121451:DESAM_RS12210
uniprot id: L0RCY2
names: Similarity
messages: Belongs to the peptidase M16 family.

1121451:DESAM RS01760
gene id: 1121451:DESAM_RS01760
uniprot id: L0R6Q0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1121451:DESAM RS02770
gene id: 1121451:DESAM_RS02770
uniprot id: L0R8Q7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS11025
gene id: 1121451:DESAM_RS11025
uniprot id: L0RC59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1121451:DESAM RS15025
gene id: 1121451:DESAM_RS15025
uniprot id: L0RG50
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS02520
gene id: 1121451:DESAM_RS02520
uniprot id: L0R8J9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1121451:DESAM RS08480
gene id: 1121451:DESAM_RS08480
uniprot id: L0RC99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1121451:DESAM RS07320
gene id: 1121451:DESAM_RS07320
uniprot id: L0RA03
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1121451:DESAM RS06830
gene id: 1121451:DESAM_RS06830
uniprot id: L0RBD4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1121451:DESAM RS10855
gene id: 1121451:DESAM_RS10855
uniprot id: L0RDM9
names: Similarity
messages: Belongs to the RutC family.

1121451:DESAM RS00630
gene id: 1121451:DESAM_RS00630
uniprot id: L0R609
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1121451:DESAM RS03995
gene id: 1121451:DESAM_RS03995
uniprot id: L0R806
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121451:DESAM RS04930
gene id: 1121451:DESAM_RS04930
uniprot id: L0RBZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121451:DESAM RS03620
gene id: 1121451:DESAM_RS03620
uniprot id: L0R7T2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1121451:DESAM RS04995
gene id: 1121451:DESAM_RS04995
uniprot id: L0R8K0
names: Similarity
messages: Belongs to the GPI family.

1121451:DESAM RS09210
gene id: 1121451:DESAM_RS09210
uniprot id: L0RB54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1121451:DESAM RS01400
gene id: 1121451:DESAM_RS01400
uniprot id: L0R7Y8
names: Similarity
messages: Belongs to the NAD synthetase family.

1121451:DESAM RS15260
gene id: 1121451:DESAM_RS15260
uniprot id: L0RGC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1121451:DESAM RS11680
gene id: 1121451:DESAM_RS11680
uniprot id: L0RG26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1121451:DESAM RS06440
gene id: 1121451:DESAM_RS06440
uniprot id: L0R9G2
names: Similarity
names: Subunit
messages: Belongs to the organic radical-activating enzymes family.
messages: Monomer.

1121451:DESAM RS04575
gene id: 1121451:DESAM_RS04575
uniprot id: L0R8C2
names: Similarity
messages: Belongs to the peptidase S49 family.

1121451:DESAM RS04860
gene id: 1121451:DESAM_RS04860
uniprot id: L0RBY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS11795
gene id: 1121451:DESAM_RS11795
uniprot id: L0REB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1121451:DESAM RS12920
gene id: 1121451:DESAM_RS12920
uniprot id: L0REY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1121451:DESAM RS14400
gene id: 1121451:DESAM_RS14400
uniprot id: L0RE90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS05355
gene id: 1121451:DESAM_RS05355
uniprot id: L0RC69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121451:DESAM RS00185
gene id: 1121451:DESAM_RS00185
uniprot id: L0R763
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121451:DESAM RS08325
gene id: 1121451:DESAM_RS08325
uniprot id: L0RAJ6
names: Similarity
messages: Belongs to the UPF0751 family.

1121451:DESAM RS06300
gene id: 1121451:DESAM_RS06300
uniprot id: L0R9D4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1121451:DESAM RS12755
gene id: 1121451:DESAM_RS12755
uniprot id: L0REW0
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1121451:DESAM RS07735
gene id: 1121451:DESAM_RS07735
uniprot id: L0RBR6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS13275
gene id: 1121451:DESAM_RS13275
uniprot id: L0RGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1121451:DESAM RS15825
gene id: 1121451:DESAM_RS15825
uniprot id: L0RIE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1121451:DESAM RS10220
gene id: 1121451:DESAM_RS10220
uniprot id: L0RF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1121451:DESAM RS02040
gene id: 1121451:DESAM_RS02040
uniprot id: L0RA73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1121451:DESAM RS06850
gene id: 1121451:DESAM_RS06850
uniprot id: L0RBD8
names: Similarity
messages: Belongs to the glutamate synthase family.

1121451:DESAM RS16265
gene id: 1121451:DESAM_RS16265
uniprot id: L0RGY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS11865
gene id: 1121451:DESAM_RS11865
uniprot id: L0RCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1121451:DESAM RS11435
gene id: 1121451:DESAM_RS11435
uniprot id: L0RE50
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1121451:DESAM RS09230
gene id: 1121451:DESAM_RS09230
uniprot id: L0RB30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121451:DESAM RS08575
gene id: 1121451:DESAM_RS08575
uniprot id: L0RCB6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1121451:DESAM RS16340
gene id: 1121451:DESAM_RS16340
uniprot id: L0RIT0
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121451:DESAM RS09410
gene id: 1121451:DESAM_RS09410
uniprot id: L0RB90
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS01640
gene id: 1121451:DESAM_RS01640
uniprot id: L0R6M9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121451:DESAM RS02860
gene id: 1121451:DESAM_RS02860
uniprot id: L0R7D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1121451:DESAM RS10670
gene id: 1121451:DESAM_RS10670
uniprot id: L0RFD3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121451:DESAM RS11870
gene id: 1121451:DESAM_RS11870
uniprot id: L0RG59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1121451:DESAM RS06030
gene id: 1121451:DESAM_RS06030
uniprot id: L0RAQ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1121451:DESAM RS11980
gene id: 1121451:DESAM_RS11980
uniprot id: L0RCQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS11770
gene id: 1121451:DESAM_RS11770
uniprot id: L0REB5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1121451:DESAM RS09030
gene id: 1121451:DESAM_RS09030
uniprot id: L0RB02
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121451:DESAM RS03435
gene id: 1121451:DESAM_RS03435
uniprot id: L0R7P5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1121451:DESAM RS09780
gene id: 1121451:DESAM_RS09780
uniprot id: L0RD18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121451:DESAM RS10240
gene id: 1121451:DESAM_RS10240
uniprot id: L0RDB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1121451:DESAM RS02985
gene id: 1121451:DESAM_RS02985
uniprot id: L0RAQ8
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS06325
gene id: 1121451:DESAM_RS06325
uniprot id: L0R9E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1121451:DESAM RS00480
gene id: 1121451:DESAM_RS00480
uniprot id: L0R7A3
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS06445
gene id: 1121451:DESAM_RS06445
uniprot id: L0R9G5
names: Subunit
messages: Homodimer.

1121451:DESAM RS04200
gene id: 1121451:DESAM_RS04200
uniprot id: L0R851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1121451:DESAM RS13580
gene id: 1121451:DESAM_RS13580
uniprot id: L0RH81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121451:DESAM RS06485
gene id: 1121451:DESAM_RS06485
uniprot id: L0R9I8
names: Subcellular Location Annotation
messages: Cytoplasm

1121451:DESAM RS10460
gene id: 1121451:DESAM_RS10460
uniprot id: L0RBS8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1121451:DESAM RS11995
gene id: 1121451:DESAM_RS11995
uniprot id: L0RG82
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS10820
gene id: 1121451:DESAM_RS10820
uniprot id: L0RC41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121451:DESAM RS08715
gene id: 1121451:DESAM_RS08715
uniprot id: L0RCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS08945
gene id: 1121451:DESAM_RS08945
uniprot id: L0RB10
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121451:DESAM RS00860
gene id: 1121451:DESAM_RS00860
uniprot id: L0R9B9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS16355
gene id: 1121451:DESAM_RS16355
uniprot id: L0RIT5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1121451:DESAM RS05430
gene id: 1121451:DESAM_RS05430
uniprot id: L0RAD0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1121451:DESAM RS15235
gene id: 1121451:DESAM_RS15235
uniprot id: L0RGB5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1121451:DESAM RS10315
gene id: 1121451:DESAM_RS10315
uniprot id: L0RF65
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121451:DESAM RS11035
gene id: 1121451:DESAM_RS11035
uniprot id: L0RDR9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121451:DESAM RS11655
gene id: 1121451:DESAM_RS11655
uniprot id: L0RE92
names: Similarity
messages: Belongs to the UPF0173 family.

1121451:DESAM RS11420
gene id: 1121451:DESAM_RS11420
uniprot id: L0RE25
names: Similarity
messages: Belongs to the hemerythrin family.

1121451:DESAM RS12235
gene id: 1121451:DESAM_RS12235
uniprot id: L0REK1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1121451:DESAM RS07125
gene id: 1121451:DESAM_RS07125
uniprot id: L0RBE9
names: Similarity
messages: Belongs to the DDAH family.

1121451:DESAM RS04355
gene id: 1121451:DESAM_RS04355
uniprot id: L0R9U9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1121451:DESAM RS00620
gene id: 1121451:DESAM_RS00620
uniprot id: L0R7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1121451:DESAM RS13530
gene id: 1121451:DESAM_RS13530
uniprot id: L0RFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

1121451:DESAM RS05040
gene id: 1121451:DESAM_RS05040
uniprot id: L0RC10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1121451:DESAM RS10450
gene id: 1121451:DESAM_RS10450
uniprot id: L0RF90
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS08640
gene id: 1121451:DESAM_RS08640
uniprot id: L0RAR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121451:DESAM RS01725
gene id: 1121451:DESAM_RS01725
uniprot id: L0R9X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1121451:DESAM RS04345
gene id: 1121451:DESAM_RS04345
uniprot id: L0R872
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121451:DESAM RS07885
gene id: 1121451:DESAM_RS07885
uniprot id: L0RDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS15610
gene id: 1121451:DESAM_RS15610
uniprot id: L0RI89
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS09105
gene id: 1121451:DESAM_RS09105
uniprot id: L0RB39
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121451:DESAM RS13280
gene id: 1121451:DESAM_RS13280
uniprot id: L0RF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1121451:DESAM RS15985
gene id: 1121451:DESAM_RS15985
uniprot id: L0RGQ6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1121451:DESAM RS12180
gene id: 1121451:DESAM_RS12180
uniprot id: L0RCU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS15335
gene id: 1121451:DESAM_RS15335
uniprot id: L0RI39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1121451:DESAM RS07750
gene id: 1121451:DESAM_RS07750
uniprot id: L0RBV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS10495
gene id: 1121451:DESAM_RS10495
uniprot id: L0RFA0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1121451:DESAM RS06190
gene id: 1121451:DESAM_RS06190
uniprot id: L0R9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1121451:DESAM RS09610
gene id: 1121451:DESAM_RS09610
uniprot id: L0RCW5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121451:DESAM RS03015
gene id: 1121451:DESAM_RS03015
uniprot id: L0R8V7
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS14705
gene id: 1121451:DESAM_RS14705
uniprot id: L0REB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1121451:DESAM RS06795
gene id: 1121451:DESAM_RS06795
uniprot id: L0RD54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS15205
gene id: 1121451:DESAM_RS15205
uniprot id: L0RER1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1121451:DESAM RS14415
gene id: 1121451:DESAM_RS14415
uniprot id: L0RE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS04550
gene id: 1121451:DESAM_RS04550
uniprot id: L0R8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121451:DESAM RS02410
gene id: 1121451:DESAM_RS02410
uniprot id: L0R735
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1121451:DESAM RS14285
gene id: 1121451:DESAM_RS14285
uniprot id: L0RE29
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS10245
gene id: 1121451:DESAM_RS10245
uniprot id: L0RF54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121451:DESAM RS04780
gene id: 1121451:DESAM_RS04780
uniprot id: L0R8E9
names: Similarity
messages: Belongs to the MotB family.

1121451:DESAM RS12980
gene id: 1121451:DESAM_RS12980
uniprot id: L0RGR1
names: Similarity
messages: Belongs to the universal stress protein A family.

1121451:DESAM RS16530
gene id: 1121451:DESAM_RS16530
uniprot id: L0RFJ5
names: Similarity
messages: Belongs to the peptidase S16 family.

1121451:DESAM RS09255
gene id: 1121451:DESAM_RS09255
uniprot id: L0RB33
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1121451:DESAM RS05195
gene id: 1121451:DESAM_RS05195
uniprot id: L0R8N7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1121451:DESAM RS03525
gene id: 1121451:DESAM_RS03525
uniprot id: L0R7R4
names: Similarity
messages: Belongs to the MlaA family.

1121451:DESAM RS00595
gene id: 1121451:DESAM_RS00595
uniprot id: L0R7F6
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS12990
gene id: 1121451:DESAM_RS12990
uniprot id: L0RDD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1121451:DESAM RS12465
gene id: 1121451:DESAM_RS12465
uniprot id: L0REN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1121451:DESAM RS16435
gene id: 1121451:DESAM_RS16435
uniprot id: L0RFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1121451:DESAM RS00555
gene id: 1121451:DESAM_RS00555
uniprot id: L0R7C1
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS08205
gene id: 1121451:DESAM_RS08205
uniprot id: L0RC49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1121451:DESAM RS06990
gene id: 1121451:DESAM_RS06990
uniprot id: L0R9T8
names: Similarity
messages: Belongs to the peptidase C40 family.

1121451:DESAM RS12240
gene id: 1121451:DESAM_RS12240
uniprot id: L0RGC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

1121451:DESAM RS00190
gene id: 1121451:DESAM_RS00190
uniprot id: L0R8Y1
names: Similarity
messages: Belongs to the Skp family.

1121451:DESAM RS10235
gene id: 1121451:DESAM_RS10235
uniprot id: L0RBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1121451:DESAM RS02765
gene id: 1121451:DESAM_RS02765
uniprot id: L0R8V1
names: Similarity
messages: Belongs to the LOG family.

1121451:DESAM RS12310
gene id: 1121451:DESAM_RS12310
uniprot id: L0RGE2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1121451:DESAM RS05350
gene id: 1121451:DESAM_RS05350
uniprot id: L0RAD8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS15310
gene id: 1121451:DESAM_RS15310
uniprot id: L0RI35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1121451:DESAM RS08385
gene id: 1121451:DESAM_RS08385
uniprot id: L0RC87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1121451:DESAM RS00460
gene id: 1121451:DESAM_RS00460
uniprot id: L0R798
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1121451:DESAM RS03760
gene id: 1121451:DESAM_RS03760
uniprot id: L0R7V8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS02630
gene id: 1121451:DESAM_RS02630
uniprot id: L0R8M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1121451:DESAM RS03835
gene id: 1121451:DESAM_RS03835
uniprot id: L0R7X5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1121451:DESAM RS12000
gene id: 1121451:DESAM_RS12000
uniprot id: L0RED3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1121451:DESAM RS04865
gene id: 1121451:DESAM_RS04865
uniprot id: L0RA13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS08985
gene id: 1121451:DESAM_RS08985
uniprot id: L0RAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1121451:DESAM RS11080
gene id: 1121451:DESAM_RS11080
uniprot id: L0RCA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

1121451:DESAM RS03625
gene id: 1121451:DESAM_RS03625
uniprot id: L0R7S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1121451:DESAM RS09200
gene id: 1121451:DESAM_RS09200
uniprot id: L0RCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1121451:DESAM RS07835
gene id: 1121451:DESAM_RS07835
uniprot id: L0RAA4
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS03845
gene id: 1121451:DESAM_RS03845
uniprot id: L0RB83
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121451:DESAM RS11100
gene id: 1121451:DESAM_RS11100
uniprot id: L0RCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1121451:DESAM RS01880
gene id: 1121451:DESAM_RS01880
uniprot id: L0R6S3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121451:DESAM RS11930
gene id: 1121451:DESAM_RS11930
uniprot id: L0RCP7
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1121451:DESAM RS13270
gene id: 1121451:DESAM_RS13270
uniprot id: L0RF58
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1121451:DESAM RS02175
gene id: 1121451:DESAM_RS02175
uniprot id: L0R8D3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1121451:DESAM RS13820
gene id: 1121451:DESAM_RS13820
uniprot id: L0RDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121451:DESAM RS07550
gene id: 1121451:DESAM_RS07550
uniprot id: L0RBN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
messages: Monomer.

1121451:DESAM RS03880
gene id: 1121451:DESAM_RS03880
uniprot id: L0R7Y1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121451:DESAM RS06985
gene id: 1121451:DESAM_RS06985
uniprot id: L0R9Q8
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS03415
gene id: 1121451:DESAM_RS03415
uniprot id: L0R7N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS15270
gene id: 1121451:DESAM_RS15270
uniprot id: L0RGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1121451:DESAM RS02450
gene id: 1121451:DESAM_RS02450
uniprot id: L0RAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1121451:DESAM RS14865
gene id: 1121451:DESAM_RS14865
uniprot id: L0RHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1121451:DESAM RS09445
gene id: 1121451:DESAM_RS09445
uniprot id: L0REQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1121451:DESAM RS05645
gene id: 1121451:DESAM_RS05645
uniprot id: L0R8Y3
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1121451:DESAM RS11065
gene id: 1121451:DESAM_RS11065
uniprot id: L0RDU9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1121451:DESAM RS13790
gene id: 1121451:DESAM_RS13790
uniprot id: L0RFF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1121451:DESAM RS10015
gene id: 1121451:DESAM_RS10015
uniprot id: L0RD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1121451:DESAM RS01635
gene id: 1121451:DESAM_RS01635
uniprot id: L0R803
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121451:DESAM RS03490
gene id: 1121451:DESAM_RS03490
uniprot id: L0RB03
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121451:DESAM RS13040
gene id: 1121451:DESAM_RS13040
uniprot id: L0RDE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1121451:DESAM RS10740
gene id: 1121451:DESAM_RS10740
uniprot id: L0RBZ5
names: Similarity
messages: Belongs to the peptidase S41A family.

1121451:DESAM RS04000
gene id: 1121451:DESAM_RS04000
uniprot id: L0R811
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1121451:DESAM RS08220
gene id: 1121451:DESAM_RS08220
uniprot id: L0RAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1121451:DESAM RS04595
gene id: 1121451:DESAM_RS04595
uniprot id: L0R8B0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS12145
gene id: 1121451:DESAM_RS12145
uniprot id: L0REI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1121451:DESAM RS10230
gene id: 1121451:DESAM_RS10230
uniprot id: L0RBM5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1121451:DESAM RS05850
gene id: 1121451:DESAM_RS05850
uniprot id: L0RAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1121451:DESAM RS14940
gene id: 1121451:DESAM_RS14940
uniprot id: L0REG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1121451:DESAM RS04975
gene id: 1121451:DESAM_RS04975
uniprot id: L0RA62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1121451:DESAM RS02105
gene id: 1121451:DESAM_RS02105
uniprot id: L0R8G4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1121451:DESAM RS12130
gene id: 1121451:DESAM_RS12130
uniprot id: L0RCT7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1121451:DESAM RS02540
gene id: 1121451:DESAM_RS02540
uniprot id: L0RAG6
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1121451:DESAM RS12490
gene id: 1121451:DESAM_RS12490
uniprot id: L0RD16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1121451:DESAM RS15315
gene id: 1121451:DESAM_RS15315
uniprot id: L0RGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121451:DESAM RS14880
gene id: 1121451:DESAM_RS14880
uniprot id: L0RG42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1121451:DESAM RS12910
gene id: 1121451:DESAM_RS12910
uniprot id: L0REY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1121451:DESAM RS10645
gene id: 1121451:DESAM_RS10645
uniprot id: L0RDK2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1121451:DESAM RS08635
gene id: 1121451:DESAM_RS08635
uniprot id: L0RCB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1121451:DESAM RS11590
gene id: 1121451:DESAM_RS11590
uniprot id: L0RG09
names: Similarity
messages: Belongs to the TlyA family.

1121451:DESAM RS09715
gene id: 1121451:DESAM_RS09715
uniprot id: L0RD09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1121451:DESAM RS02145
gene id: 1121451:DESAM_RS02145
uniprot id: L0R6X9
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS16135
gene id: 1121451:DESAM_RS16135
uniprot id: L0RIP2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1121451:DESAM RS00355
gene id: 1121451:DESAM_RS00355
uniprot id: L0R797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121451:DESAM RS12305
gene id: 1121451:DESAM_RS12305
uniprot id: L0REL6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1121451:DESAM RS13445
gene id: 1121451:DESAM_RS13445
uniprot id: L0RDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1121451:DESAM RS03195
gene id: 1121451:DESAM_RS03195
uniprot id: L0RAU6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121451:DESAM RS08225
gene id: 1121451:DESAM_RS08225
uniprot id: L0RC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1121451:DESAM RS05305
gene id: 1121451:DESAM_RS05305
uniprot id: L0RC60
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1121451:DESAM RS06475
gene id: 1121451:DESAM_RS06475
uniprot id: L0RCY8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS15305
gene id: 1121451:DESAM_RS15305
uniprot id: L0RET2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121451:DESAM RS07180
gene id: 1121451:DESAM_RS07180
uniprot id: L0R9Y1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1121451:DESAM RS04270
gene id: 1121451:DESAM_RS04270
uniprot id: L0R861
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1121451:DESAM RS08585
gene id: 1121451:DESAM_RS08585
uniprot id: L0RCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121451:DESAM RS03265
gene id: 1121451:DESAM_RS03265
uniprot id: L0R7K8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1121451:DESAM RS14810
gene id: 1121451:DESAM_RS14810
uniprot id: L0RG27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1121451:DESAM RS03080
gene id: 1121451:DESAM_RS03080
uniprot id: L0R8W9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121451:DESAM RS07780
gene id: 1121451:DESAM_RS07780
uniprot id: L0RBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121451:DESAM RS04350
gene id: 1121451:DESAM_RS04350
uniprot id: L0R880
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121451:DESAM RS05300
gene id: 1121451:DESAM_RS05300
uniprot id: L0RAC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1121451:DESAM RS01530
gene id: 1121451:DESAM_RS01530
uniprot id: L0R6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121451:DESAM RS10665
gene id: 1121451:DESAM_RS10665
uniprot id: L0RDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1121451:DESAM RS04340
gene id: 1121451:DESAM_RS04340
uniprot id: L0R9R4
names: Similarity
messages: Belongs to the hemerythrin family.

1121451:DESAM RS08655
gene id: 1121451:DESAM_RS08655
uniprot id: L0RE68
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1121451:DESAM RS13350
gene id: 1121451:DESAM_RS13350
uniprot id: L0RF67
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS12275
gene id: 1121451:DESAM_RS12275
uniprot id: L0RCZ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121451:DESAM RS05495
gene id: 1121451:DESAM_RS05495
uniprot id: L0R8U8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1121451:DESAM RS01750
gene id: 1121451:DESAM_RS01750
uniprot id: L0R9Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121451:DESAM RS02505
gene id: 1121451:DESAM_RS02505
uniprot id: L0R733
names: Similarity
messages: Belongs to the acylphosphatase family.

1121451:DESAM RS15225
gene id: 1121451:DESAM_RS15225
uniprot id: L0REN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1121451:DESAM RS05380
gene id: 1121451:DESAM_RS05380
uniprot id: L0RAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1121451:DESAM RS14035
gene id: 1121451:DESAM_RS14035
uniprot id: L0RHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1121451:DESAM RS00235
gene id: 1121451:DESAM_RS00235
uniprot id: L0R5U6
names: Similarity
messages: Belongs to the Skp family.

1121451:DESAM RS13140
gene id: 1121451:DESAM_RS13140
uniprot id: L0RDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1121451:DESAM RS12845
gene id: 1121451:DESAM_RS12845
uniprot id: L0RDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1121451:DESAM RS13405
gene id: 1121451:DESAM_RS13405
uniprot id: L0RF84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1121451:DESAM RS16425
gene id: 1121451:DESAM_RS16425
uniprot id: L0RGY9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121451:DESAM RS12340
gene id: 1121451:DESAM_RS12340
uniprot id: L0REK5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1121451:DESAM RS12455
gene id: 1121451:DESAM_RS12455
uniprot id: L0RD36
names: Subcellular Location Annotation
messages: Membrane

1121451:DESAM RS11145
gene id: 1121451:DESAM_RS11145
uniprot id: L0RC90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1121451:DESAM RS10885
gene id: 1121451:DESAM_RS10885
uniprot id: L0RC27
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121451:DESAM RS13830
gene id: 1121451:DESAM_RS13830
uniprot id: L0RFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121451:DESAM RS06345
gene id: 1121451:DESAM_RS06345
uniprot id: L0R9E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1121451:DESAM RS09455
gene id: 1121451:DESAM_RS09455
uniprot id: L0RB67
names: Similarity
messages: Belongs to the GSP E family.

1121451:DESAM RS11090
gene id: 1121451:DESAM_RS11090
uniprot id: L0RDT3
names: Similarity
messages: Belongs to the peptidase A31 family.

1121451:DESAM RS14240
gene id: 1121451:DESAM_RS14240
uniprot id: L0RE55
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121451:DESAM RS01605
gene id: 1121451:DESAM_RS01605
uniprot id: L0R830
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.