1121448:DGI RS07135
gene id: 1121448:DGI_RS07135
uniprot id: T2GAN6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1121448:DGI RS16065
gene id: 1121448:DGI_RS16065
uniprot id: T2GFT5
names: Cofactor
names: Subunit
messages: Binds 2 irons ions per subunit via 4 cysteine residues per iron.
messages: Homodimer.

1121448:DGI RS09670
gene id: 1121448:DGI_RS09670
uniprot id: T2GCG4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1121448:DGI RS06020
gene id: 1121448:DGI_RS06020
uniprot id: T2GA29
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1121448:DGI RS14015
gene id: 1121448:DGI_RS14015
uniprot id: T2GEN1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121448:DGI RS03960
gene id: 1121448:DGI_RS03960
uniprot id: T2G8V5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1121448:DGI RS11535
gene id: 1121448:DGI_RS11535
uniprot id: T2GDQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1121448:DGI RS13460
gene id: 1121448:DGI_RS13460
uniprot id: T2GEE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS16225
gene id: 1121448:DGI_RS16225
uniprot id: T2GF45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1121448:DGI RS10765
gene id: 1121448:DGI_RS10765
uniprot id: T2GC02
names: Subunit
messages: Heterodimer of a large and a small subunit.

1121448:DGI RS08350
gene id: 1121448:DGI_RS08350
uniprot id: T2GBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS11385
gene id: 1121448:DGI_RS11385
uniprot id: T2GCB7
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS01575
gene id: 1121448:DGI_RS01575
uniprot id: T2G7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1121448:DGI RS11725
gene id: 1121448:DGI_RS11725
uniprot id: T2GCH8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1121448:DGI RS04055
gene id: 1121448:DGI_RS04055
uniprot id: T2GA06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS13000
gene id: 1121448:DGI_RS13000
uniprot id: T2GEI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1121448:DGI RS15720
gene id: 1121448:DGI_RS15720
uniprot id: T2GGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1121448:DGI RS14790
gene id: 1121448:DGI_RS14790
uniprot id: T2GFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1121448:DGI RS02375
gene id: 1121448:DGI_RS02375
uniprot id: T2G8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1121448:DGI RS08805
gene id: 1121448:DGI_RS08805
uniprot id: T2GCQ3
names: Similarity
messages: Belongs to the acylphosphatase family.

1121448:DGI RS02040
gene id: 1121448:DGI_RS02040
uniprot id: T2G839
names: Similarity
messages: Belongs to the Skp family.

1121448:DGI RS05980
gene id: 1121448:DGI_RS05980
uniprot id: T2G961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS14555
gene id: 1121448:DGI_RS14555
uniprot id: T2GF96
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121448:DGI RS03810
gene id: 1121448:DGI_RS03810
uniprot id: T2G8T0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1121448:DGI RS02095
gene id: 1121448:DGI_RS02095
uniprot id: T2G6Z2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1121448:DGI RS13435
gene id: 1121448:DGI_RS13435
uniprot id: T2GEE0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121448:DGI RS14470
gene id: 1121448:DGI_RS14470
uniprot id: T2GFV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1121448:DGI RS02880
gene id: 1121448:DGI_RS02880
uniprot id: T2G8Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1121448:DGI RS05720
gene id: 1121448:DGI_RS05720
uniprot id: T2GA83
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1121448:DGI RS17020
gene id: 1121448:DGI_RS17020
uniprot id: T2GB32
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12985
gene id: 1121448:DGI_RS12985
uniprot id: T2GE15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1121448:DGI RS08640
gene id: 1121448:DGI_RS08640
uniprot id: T2GAP8
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1121448:DGI RS07485
gene id: 1121448:DGI_RS07485
uniprot id: T2G9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1121448:DGI RS00455
gene id: 1121448:DGI_RS00455
uniprot id: T2G820
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS14275
gene id: 1121448:DGI_RS14275
uniprot id: T2GDY4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1121448:DGI RS04195
gene id: 1121448:DGI_RS04195
uniprot id: T2G855
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS08270
gene id: 1121448:DGI_RS08270
uniprot id: T2GAH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1121448:DGI RS14535
gene id: 1121448:DGI_RS14535
uniprot id: T2GE31
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS10035
gene id: 1121448:DGI_RS10035
uniprot id: T2GCU0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121448:DGI RS04675
gene id: 1121448:DGI_RS04675
uniprot id: T2G9K1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS01295
gene id: 1121448:DGI_RS01295
uniprot id: T2G7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS15330
gene id: 1121448:DGI_RS15330
uniprot id: T2GG89
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1121448:DGI RS06705
gene id: 1121448:DGI_RS06705
uniprot id: T2GAW4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1121448:DGI RS12460
gene id: 1121448:DGI_RS12460
uniprot id: T2GE28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1121448:DGI RS06985
gene id: 1121448:DGI_RS06985
uniprot id: T2GBM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1121448:DGI RS05545
gene id: 1121448:DGI_RS05545
uniprot id: T2GAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS01700
gene id: 1121448:DGI_RS01700
uniprot id: T2G8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1121448:DGI RS01135
gene id: 1121448:DGI_RS01135
uniprot id: T2G7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1121448:DGI RS01765
gene id: 1121448:DGI_RS01765
uniprot id: T2G7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1121448:DGI RS05785
gene id: 1121448:DGI_RS05785
uniprot id: T2GB15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1121448:DGI RS08645
gene id: 1121448:DGI_RS08645
uniprot id: T2GC08
names: Similarity
messages: Belongs to the peptidase M18 family.

1121448:DGI RS11800
gene id: 1121448:DGI_RS11800
uniprot id: T2GCJ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS06255
gene id: 1121448:DGI_RS06255
uniprot id: T2GAH1
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1121448:DGI RS12550
gene id: 1121448:DGI_RS12550
uniprot id: T2GEU3
names: Similarity
messages: Belongs to the PhoH family.

1121448:DGI RS05055
gene id: 1121448:DGI_RS05055
uniprot id: T2G9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1121448:DGI RS02150
gene id: 1121448:DGI_RS02150
uniprot id: T2G6Z9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family.
messages: Catalytic subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction.
messages: Consists of three sections from the N- to the C-terminus: FAD-binding domain, capping domain and helical domain. The FAD-binding domain and the capping domain slightly overlap and form a channel that may transport the substrate.
messages: Cytoplasm
messages: Heterodimer composed of AprA and AprB (PubMed:19820092, PubMed:2158885). The heterodimers can dimerize to form heterotetramers (PubMed:2158885).

1121448:DGI RS12935
gene id: 1121448:DGI_RS12935
uniprot id: T2GE04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS07680
gene id: 1121448:DGI_RS07680
uniprot id: T2GC23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1121448:DGI RS10670
gene id: 1121448:DGI_RS10670
uniprot id: T2GD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS12855
gene id: 1121448:DGI_RS12855
uniprot id: T2GF08
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1121448:DGI RS15110
gene id: 1121448:DGI_RS15110
uniprot id: T2GED3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS13980
gene id: 1121448:DGI_RS13980
uniprot id: T2GF47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121448:DGI RS08395
gene id: 1121448:DGI_RS08395
uniprot id: T2GBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121448:DGI RS12105
gene id: 1121448:DGI_RS12105
uniprot id: T2GEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1121448:DGI RS02370
gene id: 1121448:DGI_RS02370
uniprot id: T2G7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1121448:DGI RS12315
gene id: 1121448:DGI_RS12315
uniprot id: T2GCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1121448:DGI RS13810
gene id: 1121448:DGI_RS13810
uniprot id: T2GFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1121448:DGI RS02480
gene id: 1121448:DGI_RS02480
uniprot id: T2G8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121448:DGI RS15625
gene id: 1121448:DGI_RS15625
uniprot id: T2GFM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121448:DGI RS14925
gene id: 1121448:DGI_RS14925
uniprot id: T2GFK9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121448:DGI RS04015
gene id: 1121448:DGI_RS04015
uniprot id: T2G984
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1121448:DGI RS11785
gene id: 1121448:DGI_RS11785
uniprot id: T2GEF9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1121448:DGI RS01740
gene id: 1121448:DGI_RS01740
uniprot id: T2G7X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1121448:DGI RS02900
gene id: 1121448:DGI_RS02900
uniprot id: T2G7E5
names: Similarity
messages: Belongs to the UPF0173 family.

1121448:DGI RS13390
gene id: 1121448:DGI_RS13390
uniprot id: T2GEN3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1121448:DGI RS11805
gene id: 1121448:DGI_RS11805
uniprot id: T2GDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1121448:DGI RS08285
gene id: 1121448:DGI_RS08285
uniprot id: T2GBD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121448:DGI RS14825
gene id: 1121448:DGI_RS14825
uniprot id: T2GF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1121448:DGI RS13140
gene id: 1121448:DGI_RS13140
uniprot id: T2GEJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS12445
gene id: 1121448:DGI_RS12445
uniprot id: T2GE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1121448:DGI RS01425
gene id: 1121448:DGI_RS01425
uniprot id: T2G7R2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1121448:DGI RS08865
gene id: 1121448:DGI_RS08865
uniprot id: T2GBZ6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1121448:DGI RS09695
gene id: 1121448:DGI_RS09695
uniprot id: T2GCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1121448:DGI RS01075
gene id: 1121448:DGI_RS01075
uniprot id: T2G8F1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1121448:DGI RS01995
gene id: 1121448:DGI_RS01995
uniprot id: T2G7S1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS15525
gene id: 1121448:DGI_RS15525
uniprot id: T2GFT0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1121448:DGI RS07810
gene id: 1121448:DGI_RS07810
uniprot id: T2GB22
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1121448:DGI RS01275
gene id: 1121448:DGI_RS01275
uniprot id: T2G8I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS13165
gene id: 1121448:DGI_RS13165
uniprot id: T2GEK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1121448:DGI RS16025
gene id: 1121448:DGI_RS16025
uniprot id: T2GG13
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1121448:DGI RS11910
gene id: 1121448:DGI_RS11910
uniprot id: T2GDD1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS10105
gene id: 1121448:DGI_RS10105
uniprot id: T2GBJ5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS16215
gene id: 1121448:DGI_RS16215
uniprot id: T2GFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1121448:DGI RS00510
gene id: 1121448:DGI_RS00510
uniprot id: T2G706
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1121448:DGI RS00470
gene id: 1121448:DGI_RS00470
uniprot id: T2G631
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121448:DGI RS16725
gene id: 1121448:DGI_RS16725
uniprot id: T2G7F1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS14175
gene id: 1121448:DGI_RS14175
uniprot id: T2GDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1121448:DGI RS09155
gene id: 1121448:DGI_RS09155
uniprot id: T2GC53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1121448:DGI RS15980
gene id: 1121448:DGI_RS15980
uniprot id: T2GEZ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1121448:DGI RS00655
gene id: 1121448:DGI_RS00655
uniprot id: T2G747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1121448:DGI RS03120
gene id: 1121448:DGI_RS03120
uniprot id: T2G7K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121448:DGI RS05510
gene id: 1121448:DGI_RS05510
uniprot id: T2G9R4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1121448:DGI RS03480
gene id: 1121448:DGI_RS03480
uniprot id: T2G8M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1121448:DGI RS01180
gene id: 1121448:DGI_RS01180
uniprot id: T2G7C9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS03380
gene id: 1121448:DGI_RS03380
uniprot id: T2G915
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1121448:DGI RS01390
gene id: 1121448:DGI_RS01390
uniprot id: T2G7Q6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1121448:DGI RS02185
gene id: 1121448:DGI_RS02185
uniprot id: T2G8Y3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1121448:DGI RS11735
gene id: 1121448:DGI_RS11735
uniprot id: T2GEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS17280
gene id: 1121448:DGI_RS17280
uniprot id: T2GDY3
names: Similarity
messages: Belongs to the peptidase S11 family.

1121448:DGI RS15905
gene id: 1121448:DGI_RS15905
uniprot id: T2GEY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1121448:DGI RS02685
gene id: 1121448:DGI_RS02685
uniprot id: T2G981
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121448:DGI RS06055
gene id: 1121448:DGI_RS06055
uniprot id: T2G974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1121448:DGI RS10085
gene id: 1121448:DGI_RS10085
uniprot id: T2GCV1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1121448:DGI RS10115
gene id: 1121448:DGI_RS10115
uniprot id: T2GDH1
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121448:DGI RS03560
gene id: 1121448:DGI_RS03560
uniprot id: T2G8Z7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1121448:DGI RS00600
gene id: 1121448:DGI_RS00600
uniprot id: T2G7H1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS14650
gene id: 1121448:DGI_RS14650
uniprot id: T2GFB4
names: Similarity
messages: Belongs to the threonine synthase family.

1121448:DGI RS08855
gene id: 1121448:DGI_RS08855
uniprot id: T2GCR2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1121448:DGI RS07390
gene id: 1121448:DGI_RS07390
uniprot id: T2G9X8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1121448:DGI RS00840
gene id: 1121448:DGI_RS00840
uniprot id: T2G7L5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1121448:DGI RS15210
gene id: 1121448:DGI_RS15210
uniprot id: T2GEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1121448:DGI RS06510
gene id: 1121448:DGI_RS06510
uniprot id: T2G9G0
names: Similarity
messages: Belongs to the citrate synthase family.

1121448:DGI RS14445
gene id: 1121448:DGI_RS14445
uniprot id: T2GFV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1121448:DGI RS06540
gene id: 1121448:DGI_RS06540
uniprot id: T2GBE9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1121448:DGI RS14010
gene id: 1121448:DGI_RS14010
uniprot id: T2GFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1121448:DGI RS15930
gene id: 1121448:DGI_RS15930
uniprot id: T2GEY7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1121448:DGI RS13195
gene id: 1121448:DGI_RS13195
uniprot id: T2GDE5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12425
gene id: 1121448:DGI_RS12425
uniprot id: T2GER4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1121448:DGI RS03540
gene id: 1121448:DGI_RS03540
uniprot id: T2G7U2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121448:DGI RS07820
gene id: 1121448:DGI_RS07820
uniprot id: T2GA70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121448:DGI RS07395
gene id: 1121448:DGI_RS07395
uniprot id: T2GB96
names: Similarity
messages: Belongs to the class-I fumarase family.

1121448:DGI RS01100
gene id: 1121448:DGI_RS01100
uniprot id: T2G8F5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121448:DGI RS13375
gene id: 1121448:DGI_RS13375
uniprot id: T2GES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS16085
gene id: 1121448:DGI_RS16085
uniprot id: T2GGH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1121448:DGI RS01970
gene id: 1121448:DGI_RS01970
uniprot id: T2G7R5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121448:DGI RS01400
gene id: 1121448:DGI_RS01400
uniprot id: T2G7W6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1121448:DGI RS01800
gene id: 1121448:DGI_RS01800
uniprot id: T2G833
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS05010
gene id: 1121448:DGI_RS05010
uniprot id: T2G8K7
names: Similarity
messages: Belongs to the HdrA family.

1121448:DGI RS14865
gene id: 1121448:DGI_RS14865
uniprot id: T2GFF5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1121448:DGI RS15855
gene id: 1121448:DGI_RS15855
uniprot id: T2GEX2
names: Similarity
messages: Belongs to the MotB family.

1121448:DGI RS12720
gene id: 1121448:DGI_RS12720
uniprot id: T2GD26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1121448:DGI RS06725
gene id: 1121448:DGI_RS06725
uniprot id: T2G9K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1121448:DGI RS07470
gene id: 1121448:DGI_RS07470
uniprot id: T2GBX4
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

1121448:DGI RS10350
gene id: 1121448:DGI_RS10350
uniprot id: T2GD09
names: Similarity
messages: Belongs to the glutamate synthase family.

1121448:DGI RS00380
gene id: 1121448:DGI_RS00380
uniprot id: T2G6W4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1121448:DGI RS04310
gene id: 1121448:DGI_RS04310
uniprot id: T2G919
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1121448:DGI RS09635
gene id: 1121448:DGI_RS09635
uniprot id: T2GD70
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121448:DGI RS13075
gene id: 1121448:DGI_RS13075
uniprot id: T2GEN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1121448:DGI RS01000
gene id: 1121448:DGI_RS01000
uniprot id: T2G8D8
names: Similarity
messages: Belongs to the ros/MucR family.

1121448:DGI RS14450
gene id: 1121448:DGI_RS14450
uniprot id: T2GEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1121448:DGI RS15070
gene id: 1121448:DGI_RS15070
uniprot id: T2GG46
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1121448:DGI RS15740
gene id: 1121448:DGI_RS15740
uniprot id: T2GG12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1121448:DGI RS02385
gene id: 1121448:DGI_RS02385
uniprot id: T2G8E4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121448:DGI RS08030
gene id: 1121448:DGI_RS08030
uniprot id: T2GBI7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1121448:DGI RS11125
gene id: 1121448:DGI_RS11125
uniprot id: T2GDH6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1121448:DGI RS06395
gene id: 1121448:DGI_RS06395
uniprot id: T2GAK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121448:DGI RS09435
gene id: 1121448:DGI_RS09435
uniprot id: T2GCF7
names: Similarity
messages: Belongs to the peptidase C40 family.

1121448:DGI RS10155
gene id: 1121448:DGI_RS10155
uniprot id: T2GDI3
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS09020
gene id: 1121448:DGI_RS09020
uniprot id: T2GCU3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1121448:DGI RS15120
gene id: 1121448:DGI_RS15120
uniprot id: T2GG55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121448:DGI RS06370
gene id: 1121448:DGI_RS06370
uniprot id: T2GA89
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS15125
gene id: 1121448:DGI_RS15125
uniprot id: T2GF89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1121448:DGI RS00320
gene id: 1121448:DGI_RS00320
uniprot id: T2G5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1121448:DGI RS08260
gene id: 1121448:DGI_RS08260
uniprot id: T2GBC5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1121448:DGI RS07670
gene id: 1121448:DGI_RS07670
uniprot id: T2GBA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1121448:DGI RS11165
gene id: 1121448:DGI_RS11165
uniprot id: T2GDC5
names: Similarity
messages: Belongs to the hyi family.

1121448:DGI RS08725
gene id: 1121448:DGI_RS08725
uniprot id: T2GC22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1121448:DGI RS06240
gene id: 1121448:DGI_RS06240
uniprot id: T2GAM7
names: Similarity
messages: Belongs to the FeoA family.

1121448:DGI RS10860
gene id: 1121448:DGI_RS10860
uniprot id: T2GC20
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1121448:DGI RS06160
gene id: 1121448:DGI_RS06160
uniprot id: T2GAK8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1121448:DGI RS02105
gene id: 1121448:DGI_RS02105
uniprot id: T2G8X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS06945
gene id: 1121448:DGI_RS06945
uniprot id: T2GAV8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS07360
gene id: 1121448:DGI_RS07360
uniprot id: T2GAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1121448:DGI RS07445
gene id: 1121448:DGI_RS07445
uniprot id: T2GBA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1121448:DGI RS09790
gene id: 1121448:DGI_RS09790
uniprot id: T2GD98
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS08965
gene id: 1121448:DGI_RS08965
uniprot id: T2GAW1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121448:DGI RS01865
gene id: 1121448:DGI_RS01865
uniprot id: T2G7P3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1121448:DGI RS02675
gene id: 1121448:DGI_RS02675
uniprot id: T2G794
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1121448:DGI RS14120
gene id: 1121448:DGI_RS14120
uniprot id: T2GF22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1121448:DGI RS05455
gene id: 1121448:DGI_RS05455
uniprot id: T2GAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1121448:DGI RS12750
gene id: 1121448:DGI_RS12750
uniprot id: T2GEY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS16305
gene id: 1121448:DGI_RS16305
uniprot id: T2GGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1121448:DGI RS03070
gene id: 1121448:DGI_RS03070
uniprot id: T2G8U8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1121448:DGI RS08265
gene id: 1121448:DGI_RS08265
uniprot id: T2GBP9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121448:DGI RS05680
gene id: 1121448:DGI_RS05680
uniprot id: T2GAC7
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS08635
gene id: 1121448:DGI_RS08635
uniprot id: T2GBV6
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS00235
gene id: 1121448:DGI_RS00235
uniprot id: T2G7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1121448:DGI RS19165
gene id: 1121448:DGI_RS19165
uniprot id: T2G910
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS08245
gene id: 1121448:DGI_RS08245
uniprot id: T2GBT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1121448:DGI RS07145
gene id: 1121448:DGI_RS07145
uniprot id: T2G9T4
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1121448:DGI RS01535
gene id: 1121448:DGI_RS01535
uniprot id: T2G7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1121448:DGI RS03990
gene id: 1121448:DGI_RS03990
uniprot id: T2G980
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS12570
gene id: 1121448:DGI_RS12570
uniprot id: T2GCZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1121448:DGI RS00930
gene id: 1121448:DGI_RS00930
uniprot id: T2G7H0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1121448:DGI RS06735
gene id: 1121448:DGI_RS06735
uniprot id: T2GBI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121448:DGI RS01685
gene id: 1121448:DGI_RS01685
uniprot id: T2G7W5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1121448:DGI RS00945
gene id: 1121448:DGI_RS00945
uniprot id: T2G8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1121448:DGI RS04940
gene id: 1121448:DGI_RS04940
uniprot id: T2G9V4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1121448:DGI RS04750
gene id: 1121448:DGI_RS04750
uniprot id: T2G9L5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1121448:DGI RS08920
gene id: 1121448:DGI_RS08920
uniprot id: T2GAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1121448:DGI RS02870
gene id: 1121448:DGI_RS02870
uniprot id: T2G8K3
names: Similarity
messages: Belongs to the TrpF family.

1121448:DGI RS13115
gene id: 1121448:DGI_RS13115
uniprot id: T2GEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1121448:DGI RS04445
gene id: 1121448:DGI_RS04445
uniprot id: T2G8A5
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1121448:DGI RS16365
gene id: 1121448:DGI_RS16365
uniprot id: T2GG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1121448:DGI RS07380
gene id: 1121448:DGI_RS07380
uniprot id: T2GAT5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1121448:DGI RS02825
gene id: 1121448:DGI_RS02825
uniprot id: T2G7C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1121448:DGI RS03800
gene id: 1121448:DGI_RS03800
uniprot id: T2G997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1121448:DGI RS02430
gene id: 1121448:DGI_RS02430
uniprot id: T2G748
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1121448:DGI RS09035
gene id: 1121448:DGI_RS09035
uniprot id: T2GAX4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1121448:DGI RS07860
gene id: 1121448:DGI_RS07860
uniprot id: T2GA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1121448:DGI RS04220
gene id: 1121448:DGI_RS04220
uniprot id: T2G860
names: Similarity
messages: Belongs to the MotB family.

1121448:DGI RS11490
gene id: 1121448:DGI_RS11490
uniprot id: T2GDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1121448:DGI RS00030
gene id: 1121448:DGI_RS00030
uniprot id: T2G7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1121448:DGI RS08545
gene id: 1121448:DGI_RS08545
uniprot id: T2GAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1121448:DGI RS08820
gene id: 1121448:DGI_RS08820
uniprot id: T2GAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1121448:DGI RS14920
gene id: 1121448:DGI_RS14920
uniprot id: T2GE98
names: Similarity
messages: Belongs to the RecJ family.

1121448:DGI RS04205
gene id: 1121448:DGI_RS04205
uniprot id: T2GA35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1121448:DGI RS08295
gene id: 1121448:DGI_RS08295
uniprot id: T2GAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1121448:DGI RS02820
gene id: 1121448:DGI_RS02820
uniprot id: T2G8J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1121448:DGI RS11475
gene id: 1121448:DGI_RS11475
uniprot id: T2GD53
names: Subunit
messages: Homodimer.

1121448:DGI RS12485
gene id: 1121448:DGI_RS12485
uniprot id: T2GE32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS14050
gene id: 1121448:DGI_RS14050
uniprot id: T2GDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS09215
gene id: 1121448:DGI_RS09215
uniprot id: T2GCB8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1121448:DGI RS04200
gene id: 1121448:DGI_RS04200
uniprot id: T2G9H1
names: Similarity
messages: Belongs to the SfsA family.

1121448:DGI RS07110
gene id: 1121448:DGI_RS07110
uniprot id: T2GAN0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1121448:DGI RS12525
gene id: 1121448:DGI_RS12525
uniprot id: T2GET7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121448:DGI RS00450
gene id: 1121448:DGI_RS00450
uniprot id: T2G7C5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1121448:DGI RS07365
gene id: 1121448:DGI_RS07365
uniprot id: T2G9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1121448:DGI RS09765
gene id: 1121448:DGI_RS09765
uniprot id: T2GD93
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1121448:DGI RS10125
gene id: 1121448:DGI_RS10125
uniprot id: T2GBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1121448:DGI RS01215
gene id: 1121448:DGI_RS01215
uniprot id: T2G6J0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121448:DGI RS15885
gene id: 1121448:DGI_RS15885
uniprot id: T2GG32
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS07975
gene id: 1121448:DGI_RS07975
uniprot id: T2GB56
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS15870
gene id: 1121448:DGI_RS15870
uniprot id: T2GFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1121448:DGI RS10290
gene id: 1121448:DGI_RS10290
uniprot id: T2GCU4
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS05755
gene id: 1121448:DGI_RS05755
uniprot id: T2GAD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1121448:DGI RS15155
gene id: 1121448:DGI_RS15155
uniprot id: T2GEE2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121448:DGI RS06010
gene id: 1121448:DGI_RS06010
uniprot id: T2GAI0
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS13630
gene id: 1121448:DGI_RS13630
uniprot id: T2GDM1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS01005
gene id: 1121448:DGI_RS01005
uniprot id: T2G7A0
names: Similarity
messages: Belongs to the ros/MucR family.

1121448:DGI RS14760
gene id: 1121448:DGI_RS14760
uniprot id: T2GE68
names: Similarity
messages: Belongs to the UPF0234 family.

1121448:DGI RS05180
gene id: 1121448:DGI_RS05180
uniprot id: T2GAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121448:DGI RS09910
gene id: 1121448:DGI_RS09910
uniprot id: T2GDC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1121448:DGI RS05235
gene id: 1121448:DGI_RS05235
uniprot id: T2G9K3
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121448:DGI RS08045
gene id: 1121448:DGI_RS08045
uniprot id: T2GCA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1121448:DGI RS07045
gene id: 1121448:DGI_RS07045
uniprot id: T2GAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS09760
gene id: 1121448:DGI_RS09760
uniprot id: T2GCN5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121448:DGI RS07330
gene id: 1121448:DGI_RS07330
uniprot id: T2GBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1121448:DGI RS15055
gene id: 1121448:DGI_RS15055
uniprot id: T2GFI8
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1121448:DGI RS07610
gene id: 1121448:DGI_RS07610
uniprot id: Q9F0J6
uniprot id: T2GBE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Binds 1 FMN per monomer.
messages: Binds 2 iron ions per monomer.
messages: Catalyzes the four-electron reduction of one oxygen molecule to two water molecules.
messages: Homodimer.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1121448:DGI RS12705
gene id: 1121448:DGI_RS12705
uniprot id: T2GEX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1121448:DGI RS13105
gene id: 1121448:DGI_RS13105
uniprot id: T2GF99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1121448:DGI RS04790
gene id: 1121448:DGI_RS04790
uniprot id: T2GAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1121448:DGI RS10365
gene id: 1121448:DGI_RS10365
uniprot id: T2GCW1
names: Similarity
messages: Belongs to the HupF/HypC family.

1121448:DGI RS14410
gene id: 1121448:DGI_RS14410
uniprot id: T2GE08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1121448:DGI RS00910
gene id: 1121448:DGI_RS00910
uniprot id: T2G6D9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121448:DGI RS05660
gene id: 1121448:DGI_RS05660
uniprot id: T2GAY8
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS16300
gene id: 1121448:DGI_RS16300
uniprot id: T2GF57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121448:DGI RS00490
gene id: 1121448:DGI_RS00490
uniprot id: T2G775
names: Similarity
messages: Belongs to the MotB family.

1121448:DGI RS01770
gene id: 1121448:DGI_RS01770
uniprot id: T2G6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1121448:DGI RS16155
gene id: 1121448:DGI_RS16155
uniprot id: T2GG73
names: Similarity
messages: Belongs to the YggT family.

1121448:DGI RS16030
gene id: 1121448:DGI_RS16030
uniprot id: T2GF07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1121448:DGI RS05230
gene id: 1121448:DGI_RS05230
uniprot id: T2GAM4
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS13050
gene id: 1121448:DGI_RS13050
uniprot id: T2GEM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS05465
gene id: 1121448:DGI_RS05465
uniprot id: T2GA10
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121448:DGI RS10625
gene id: 1121448:DGI_RS10625
uniprot id: T2GBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1121448:DGI RS07115
gene id: 1121448:DGI_RS07115
uniprot id: T2GAZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS14835
gene id: 1121448:DGI_RS14835
uniprot id: T2GE83
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1121448:DGI RS11990
gene id: 1121448:DGI_RS11990
uniprot id: T2GDT3
names: Similarity
messages: Belongs to the peptidase C56 family.

1121448:DGI RS00955
gene id: 1121448:DGI_RS00955
uniprot id: T2G7H4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS02235
gene id: 1121448:DGI_RS02235
uniprot id: T2G8B5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1121448:DGI RS06070
gene id: 1121448:DGI_RS06070
uniprot id: T2GA37
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1121448:DGI RS10370
gene id: 1121448:DGI_RS10370
uniprot id: T2GBP7
names: Similarity
messages: Belongs to the peptidase A31 family.

1121448:DGI RS08135
gene id: 1121448:DGI_RS08135
uniprot id: T2GCE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS08870
gene id: 1121448:DGI_RS08870
uniprot id: T2GAU2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1121448:DGI RS11605
gene id: 1121448:DGI_RS11605
uniprot id: T2GCF6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS12970
gene id: 1121448:DGI_RS12970
uniprot id: T2GD74
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1121448:DGI RS15445
gene id: 1121448:DGI_RS15445
uniprot id: T2GFU2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1121448:DGI RS07210
gene id: 1121448:DGI_RS07210
uniprot id: T2GB12
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1121448:DGI RS11875
gene id: 1121448:DGI_RS11875
uniprot id: T2GCL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1121448:DGI RS08835
gene id: 1121448:DGI_RS08835
uniprot id: T2GBM4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1121448:DGI RS01165
gene id: 1121448:DGI_RS01165
uniprot id: T2G6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121448:DGI RS13100
gene id: 1121448:DGI_RS13100
uniprot id: T2GEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS01385
gene id: 1121448:DGI_RS01385
uniprot id: T2G7G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1121448:DGI RS08875
gene id: 1121448:DGI_RS08875
uniprot id: T2GC54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1121448:DGI RS13415
gene id: 1121448:DGI_RS13415
uniprot id: T2GEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the pseudouridine synthase RluA family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1121448:DGI RS12350
gene id: 1121448:DGI_RS12350
uniprot id: T2GEQ0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121448:DGI RS04100
gene id: 1121448:DGI_RS04100
uniprot id: T2G9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS00365
gene id: 1121448:DGI_RS00365
uniprot id: T2G610
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1121448:DGI RS13185
gene id: 1121448:DGI_RS13185
uniprot id: T2GE94
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS02660
gene id: 1121448:DGI_RS02660
uniprot id: T2G976
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1121448:DGI RS13175
gene id: 1121448:DGI_RS13175
uniprot id: T2GEP5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS17175
gene id: 1121448:DGI_RS17175
uniprot id: T2GC39
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1121448:DGI RS08055
gene id: 1121448:DGI_RS08055
uniprot id: T2GBJ3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1121448:DGI RS02000
gene id: 1121448:DGI_RS02000
uniprot id: T2G831
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS11340
gene id: 1121448:DGI_RS11340
uniprot id: T2GDL4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121448:DGI RS09110
gene id: 1121448:DGI_RS09110
uniprot id: T2GCA1
names: Similarity
messages: Belongs to the UPF0251 family.

1121448:DGI RS03125
gene id: 1121448:DGI_RS03125
uniprot id: T2G8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1121448:DGI RS00890
gene id: 1121448:DGI_RS00890
uniprot id: T2G7M5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS02045
gene id: 1121448:DGI_RS02045
uniprot id: T2G6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1121448:DGI RS06275
gene id: 1121448:DGI_RS06275
uniprot id: T2GA72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1121448:DGI RS13225
gene id: 1121448:DGI_RS13225
uniprot id: T2GEQ2
names: Similarity
messages: Belongs to the catalase family.

1121448:DGI RS10090
gene id: 1121448:DGI_RS10090
uniprot id: T2GDG5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1121448:DGI RS17275
gene id: 1121448:DGI_RS17275
uniprot id: T2GBZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS04910
gene id: 1121448:DGI_RS04910
uniprot id: T2G8I7
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04885
gene id: 1121448:DGI_RS04885
uniprot id: T2G8I2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1121448:DGI RS08740
gene id: 1121448:DGI_RS08740
uniprot id: T2GBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121448:DGI RS14185
gene id: 1121448:DGI_RS14185
uniprot id: T2GFS2
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1121448:DGI RS04060
gene id: 1121448:DGI_RS04060
uniprot id: T2G8X3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121448:DGI RS11815
gene id: 1121448:DGI_RS11815
uniprot id: T2GDB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1121448:DGI RS03535
gene id: 1121448:DGI_RS03535
uniprot id: T2G8Z3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1121448:DGI RS08290
gene id: 1121448:DGI_RS08290
uniprot id: T2GBQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121448:DGI RS07550
gene id: 1121448:DGI_RS07550
uniprot id: T2GAW9
names: Similarity
messages: Belongs to the CutA family.

1121448:DGI RS10815
gene id: 1121448:DGI_RS10815
uniprot id: T2GC11
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1121448:DGI RS09220
gene id: 1121448:DGI_RS09220
uniprot id: T2GCY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1121448:DGI RS12080
gene id: 1121448:DGI_RS12080
uniprot id: T2GEK5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121448:DGI RS03210
gene id: 1121448:DGI_RS03210
uniprot id: T2G8I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1121448:DGI RS16375
gene id: 1121448:DGI_RS16375
uniprot id: T2GGA1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1121448:DGI RS15645
gene id: 1121448:DGI_RS15645
uniprot id: T2GFZ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1121448:DGI RS12680
gene id: 1121448:DGI_RS12680
uniprot id: T2GEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS02225
gene id: 1121448:DGI_RS02225
uniprot id: T2G872
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1121448:DGI RS08280
gene id: 1121448:DGI_RS08280
uniprot id: T2GCG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1121448:DGI RS00900
gene id: 1121448:DGI_RS00900
uniprot id: T2G785
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1121448:DGI RS08840
gene id: 1121448:DGI_RS08840
uniprot id: T2GBZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS07500
gene id: 1121448:DGI_RS07500
uniprot id: T2GAV9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1121448:DGI RS05945
gene id: 1121448:DGI_RS05945
uniprot id: T2GA18
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS16360
gene id: 1121448:DGI_RS16360
uniprot id: T2GFX4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1121448:DGI RS04110
gene id: 1121448:DGI_RS04110
uniprot id: T2G8Y1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1121448:DGI RS12775
gene id: 1121448:DGI_RS12775
uniprot id: T2GEZ3
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS09830
gene id: 1121448:DGI_RS09830
uniprot id: T2GCQ0
names: Similarity
messages: Belongs to the UPF0111 family.

1121448:DGI RS06320
gene id: 1121448:DGI_RS06320
uniprot id: T2GBA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121448:DGI RS08945
gene id: 1121448:DGI_RS08945
uniprot id: T2GAV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1121448:DGI RS07185
gene id: 1121448:DGI_RS07185
uniprot id: T2GB07
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1121448:DGI RS14390
gene id: 1121448:DGI_RS14390
uniprot id: T2GFB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121448:DGI RS16170
gene id: 1121448:DGI_RS16170
uniprot id: T2GG37
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121448:DGI RS02490
gene id: 1121448:DGI_RS02490
uniprot id: T2G8G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1121448:DGI RS13365
gene id: 1121448:DGI_RS13365
uniprot id: T2GEM9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1121448:DGI RS03100
gene id: 1121448:DGI_RS03100
uniprot id: T2G9I9
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1121448:DGI RS13120
gene id: 1121448:DGI_RS13120
uniprot id: T2GDD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1121448:DGI RS15630
gene id: 1121448:DGI_RS15630
uniprot id: T2GFV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1121448:DGI RS05880
gene id: 1121448:DGI_RS05880
uniprot id: T2G942
names: Similarity
messages: Belongs to the hemerythrin family.

1121448:DGI RS09750
gene id: 1121448:DGI_RS09750
uniprot id: T2GCI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1121448:DGI RS01950
gene id: 1121448:DGI_RS01950
uniprot id: T2G821
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS01555
gene id: 1121448:DGI_RS01555
uniprot id: T2G6P8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1121448:DGI RS05480
gene id: 1121448:DGI_RS05480
uniprot id: T2GAT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1121448:DGI RS12595
gene id: 1121448:DGI_RS12595
uniprot id: T2GD02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1121448:DGI RS13300
gene id: 1121448:DGI_RS13300
uniprot id: T2GER5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1121448:DGI RS12050
gene id: 1121448:DGI_RS12050
uniprot id: T2GE00
names: Similarity
messages: Belongs to the peptidase M29 family.

1121448:DGI RS08550
gene id: 1121448:DGI_RS08550
uniprot id: T2GBY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1121448:DGI RS12635
gene id: 1121448:DGI_RS12635
uniprot id: T2GDT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121448:DGI RS16075
gene id: 1121448:DGI_RS16075
uniprot id: T2GF16
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1121448:DGI RS11575
gene id: 1121448:DGI_RS11575
uniprot id: T2GDK3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1121448:DGI RS13085
gene id: 1121448:DGI_RS13085
uniprot id: T2GE77
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1121448:DGI RS11585
gene id: 1121448:DGI_RS11585
uniprot id: T2GDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1121448:DGI RS18660
gene id: 1121448:DGI_RS18660
uniprot id: T2G907
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121448:DGI RS03305
gene id: 1121448:DGI_RS03305
uniprot id: T2G902
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1121448:DGI RS05200
gene id: 1121448:DGI_RS05200
uniprot id: T2GA07
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121448:DGI RS16130
gene id: 1121448:DGI_RS16130
uniprot id: T2GG70
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS16370
gene id: 1121448:DGI_RS16370
uniprot id: T2GF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1121448:DGI RS05255
gene id: 1121448:DGI_RS05255
uniprot id: T2GAN2
names: Similarity
messages: Belongs to the HypE family.

1121448:DGI RS01160
gene id: 1121448:DGI_RS01160
uniprot id: T2G7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121448:DGI RS11730
gene id: 1121448:DGI_RS11730
uniprot id: T2GDT6
names: Similarity
messages: Belongs to the P(II) protein family.

1121448:DGI RS10285
gene id: 1121448:DGI_RS10285
uniprot id: T2GCG9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS00485
gene id: 1121448:DGI_RS00485
uniprot id: T2G6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121448:DGI RS05940
gene id: 1121448:DGI_RS05940
uniprot id: T2GB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1121448:DGI RS10430
gene id: 1121448:DGI_RS10430
uniprot id: T2GD22
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1121448:DGI RS11530
gene id: 1121448:DGI_RS11530
uniprot id: T2GCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1121448:DGI RS07205
gene id: 1121448:DGI_RS07205
uniprot id: T2GAQ1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1121448:DGI RS09660
gene id: 1121448:DGI_RS09660
uniprot id: T2GD75
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04075
gene id: 1121448:DGI_RS04075
uniprot id: T2G9E9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS10375
gene id: 1121448:DGI_RS10375
uniprot id: T2GD14
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1121448:DGI RS15735
gene id: 1121448:DGI_RS15735
uniprot id: T2GEV0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS11855
gene id: 1121448:DGI_RS11855
uniprot id: T2GDV9
names: Similarity
messages: Belongs to the GSP E family.

1121448:DGI RS12020
gene id: 1121448:DGI_RS12020
uniprot id: T2GCN7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1121448:DGI RS03145
gene id: 1121448:DGI_RS03145
uniprot id: T2G7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1121448:DGI RS16020
gene id: 1121448:DGI_RS16020
uniprot id: T2GFS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1121448:DGI RS15900
gene id: 1121448:DGI_RS15900
uniprot id: T2GFZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1121448:DGI RS00585
gene id: 1121448:DGI_RS00585
uniprot id: T2G731
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS01150
gene id: 1121448:DGI_RS01150
uniprot id: T2G8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1121448:DGI RS10550
gene id: 1121448:DGI_RS10550
uniprot id: T2GBU6
names: Similarity
messages: Belongs to the GcvT family.

1121448:DGI RS03460
gene id: 1121448:DGI_RS03460
uniprot id: T2G8M2
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS14540
gene id: 1121448:DGI_RS14540
uniprot id: T2GFE1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS02605
gene id: 1121448:DGI_RS02605
uniprot id: T2G843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS03375
gene id: 1121448:DGI_RS03375
uniprot id: T2G7R1
names: Similarity
messages: Belongs to the TlyA family.

1121448:DGI RS01470
gene id: 1121448:DGI_RS01470
uniprot id: T2G8L4
names: Similarity
messages: Belongs to the histone deacetylase family.

1121448:DGI RS02460
gene id: 1121448:DGI_RS02460
uniprot id: T2G753
names: Subcellular Location Annotation
messages: Periplasm

1121448:DGI RS03265
gene id: 1121448:DGI_RS03265
uniprot id: T2G8V0
names: Similarity
messages: Belongs to the GARS family.

1121448:DGI RS14140
gene id: 1121448:DGI_RS14140
uniprot id: T2GEQ1
names: Similarity
messages: Belongs to the UPF0047 family.

1121448:DGI RS03385
gene id: 1121448:DGI_RS03385
uniprot id: T2G9P3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1121448:DGI RS09625
gene id: 1121448:DGI_RS09625
uniprot id: T2GB98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1121448:DGI RS15325
gene id: 1121448:DGI_RS15325
uniprot id: T2GFN2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1121448:DGI RS13625
gene id: 1121448:DGI_RS13625
uniprot id: T2GES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1121448:DGI RS15850
gene id: 1121448:DGI_RS15850
uniprot id: T2GFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1121448:DGI RS08810
gene id: 1121448:DGI_RS08810
uniprot id: T2GBM1
names: Similarity
messages: Belongs to the UPF0758 family.

1121448:DGI RS10665
gene id: 1121448:DGI_RS10665
uniprot id: T2GCR8
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

1121448:DGI RS01645
gene id: 1121448:DGI_RS01645
uniprot id: T2G805
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1121448:DGI RS06405
gene id: 1121448:DGI_RS06405
uniprot id: T2GAQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1121448:DGI RS05030
gene id: 1121448:DGI_RS05030
uniprot id: T2G9S1
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121448:DGI RS00520
gene id: 1121448:DGI_RS00520
uniprot id: T2G653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121448:DGI RS13110
gene id: 1121448:DGI_RS13110
uniprot id: T2GE82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1121448:DGI RS15505
gene id: 1121448:DGI_RS15505
uniprot id: T2GEL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS10205
gene id: 1121448:DGI_RS10205
uniprot id: T2GDJ6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04215
gene id: 1121448:DGI_RS04215
uniprot id: T2G9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1121448:DGI RS13065
gene id: 1121448:DGI_RS13065
uniprot id: T2GEI8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1121448:DGI RS00210
gene id: 1121448:DGI_RS00210
uniprot id: Q9KIT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the flavoredoxin family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Participates in the reduction of hydrogensulfite from hydrogen.

1121448:DGI RS02485
gene id: 1121448:DGI_RS02485
uniprot id: T2G758
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1121448:DGI RS06145
gene id: 1121448:DGI_RS06145
uniprot id: T2GA51
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121448:DGI RS08330
gene id: 1121448:DGI_RS08330
uniprot id: T2GCH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1121448:DGI RS03955
gene id: 1121448:DGI_RS03955
uniprot id: T2G9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS05040
gene id: 1121448:DGI_RS05040
uniprot id: T2G9X5
names: Similarity
messages: Belongs to the AOR/FOR family.

1121448:DGI RS08830
gene id: 1121448:DGI_RS08830
uniprot id: T2GCQ8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1121448:DGI RS12390
gene id: 1121448:DGI_RS12390
uniprot id: T2GCW2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS02420
gene id: 1121448:DGI_RS02420
uniprot id: T2G808
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1121448:DGI RS14635
gene id: 1121448:DGI_RS14635
uniprot id: T2GFG1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1121448:DGI RS16010
gene id: 1121448:DGI_RS16010
uniprot id: T2GG52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1121448:DGI RS00630
gene id: 1121448:DGI_RS00630
uniprot id: T2G876
names: Subunit
messages: Homodimer.

1121448:DGI RS11550
gene id: 1121448:DGI_RS11550
uniprot id: T2GDJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1121448:DGI RS01650
gene id: 1121448:DGI_RS01650
uniprot id: T2G8P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1121448:DGI RS06050
gene id: 1121448:DGI_RS06050
uniprot id: T2GAD3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1121448:DGI RS10140
gene id: 1121448:DGI_RS10140
uniprot id: T2GCD8
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1121448:DGI RS08490
gene id: 1121448:DGI_RS08490
uniprot id: T2GBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1121448:DGI RS03685
gene id: 1121448:DGI_RS03685
uniprot id: T2G922
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1121448:DGI RS17450
gene id: 1121448:DGI_RS17450
uniprot id: T2GEF5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04725
gene id: 1121448:DGI_RS04725
uniprot id: T2G9L0
names: Similarity
messages: Belongs to the peptidase S16 family.

1121448:DGI RS09640
gene id: 1121448:DGI_RS09640
uniprot id: T2GC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121448:DGI RS02905
gene id: 1121448:DGI_RS02905
uniprot id: T2G8Q4
names: Similarity
messages: Belongs to the GSP E family.

1121448:DGI RS12580
gene id: 1121448:DGI_RS12580
uniprot id: T2GEU9
names: Similarity
messages: Belongs to the peptidase S41A family.

1121448:DGI RS16090
gene id: 1121448:DGI_RS16090
uniprot id: T2GFT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1121448:DGI RS12800
gene id: 1121448:DGI_RS12800
uniprot id: T2GEZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1121448:DGI RS12990
gene id: 1121448:DGI_RS12990
uniprot id: T2GEC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1121448:DGI RS07040
gene id: 1121448:DGI_RS07040
uniprot id: T2GAL4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1121448:DGI RS02470
gene id: 1121448:DGI_RS02470
uniprot id: T2G937
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1121448:DGI RS03150
gene id: 1121448:DGI_RS03150
uniprot id: T2G8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1121448:DGI RS14855
gene id: 1121448:DGI_RS14855
uniprot id: T2GG14
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1121448:DGI RS06605
gene id: 1121448:DGI_RS06605
uniprot id: T2G9H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1121448:DGI RS09880
gene id: 1121448:DGI_RS09880
uniprot id: T2GCQ9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1121448:DGI RS04720
gene id: 1121448:DGI_RS04720
uniprot id: T2G9A0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1121448:DGI RS09025
gene id: 1121448:DGI_RS09025
uniprot id: T2GBQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1121448:DGI RS06120
gene id: 1121448:DGI_RS06120
uniprot id: T2GA47
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1121448:DGI RS10590
gene id: 1121448:DGI_RS10590
uniprot id: T2GCQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1121448:DGI RS04290
gene id: 1121448:DGI_RS04290
uniprot id: T2G9D6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1121448:DGI RS01185
gene id: 1121448:DGI_RS01185
uniprot id: T2G7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1121448:DGI RS12420
gene id: 1121448:DGI_RS12420
uniprot id: T2GE69
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS12640
gene id: 1121448:DGI_RS12640
uniprot id: T2GE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1121448:DGI RS10330
gene id: 1121448:DGI_RS10330
uniprot id: T2GDM5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1121448:DGI RS13035
gene id: 1121448:DGI_RS13035
uniprot id: T2GE36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1121448:DGI RS08080
gene id: 1121448:DGI_RS08080
uniprot id: T2GCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS06700
gene id: 1121448:DGI_RS06700
uniprot id: T2G9J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1121448:DGI RS05560
gene id: 1121448:DGI_RS05560
uniprot id: T2GA85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS13420
gene id: 1121448:DGI_RS13420
uniprot id: T2GDI2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12925
gene id: 1121448:DGI_RS12925
uniprot id: T2GEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121448:DGI RS08020
gene id: 1121448:DGI_RS08020
uniprot id: T2GC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1121448:DGI RS01190
gene id: 1121448:DGI_RS01190
uniprot id: T2G6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121448:DGI RS07070
gene id: 1121448:DGI_RS07070
uniprot id: T2GAY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1121448:DGI RS06325
gene id: 1121448:DGI_RS06325
uniprot id: T2GAI6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS18465
gene id: 1121448:DGI_RS18465
uniprot id: T2GEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1121448:DGI RS12980
gene id: 1121448:DGI_RS12980
uniprot id: T2GF37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1121448:DGI RS00635
gene id: 1121448:DGI_RS00635
uniprot id: T2G742
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1121448:DGI RS07085
gene id: 1121448:DGI_RS07085
uniprot id: T2GAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1121448:DGI RS14310
gene id: 1121448:DGI_RS14310
uniprot id: T2GFT7
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS07575
gene id: 1121448:DGI_RS07575
uniprot id: Q01095
uniprot id: T2GB90
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Electron-transfer proteins that function in various electron transport systems in microorganisms. Functionally interchangeable with ferredoxin.
messages: Low-potential electron donor to a number of redox enzymes.

1121448:DGI RS13280
gene id: 1121448:DGI_RS13280
uniprot id: T2GFC9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS03140
gene id: 1121448:DGI_RS03140
uniprot id: T2G8S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1121448:DGI RS05385
gene id: 1121448:DGI_RS05385
uniprot id: T2GAQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1121448:DGI RS07400
gene id: 1121448:DGI_RS07400
uniprot id: T2GBV9
names: Similarity
messages: Belongs to the class-I fumarase family.

1121448:DGI RS12740
gene id: 1121448:DGI_RS12740
uniprot id: T2GE75
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121448:DGI RS06730
gene id: 1121448:DGI_RS06730
uniprot id: T2GAW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121448:DGI RS13440
gene id: 1121448:DGI_RS13440
uniprot id: T2GEP0
names: Similarity
messages: Belongs to the PhoH family.

1121448:DGI RS05570
gene id: 1121448:DGI_RS05570
uniprot id: T2G9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS01840
gene id: 1121448:DGI_RS01840
uniprot id: T2G7Z9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121448:DGI RS15970
gene id: 1121448:DGI_RS15970
uniprot id: T2GFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1121448:DGI RS08115
gene id: 1121448:DGI_RS08115
uniprot id: T2GBL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS02555
gene id: 1121448:DGI_RS02555
uniprot id: T2G834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1121448:DGI RS13495
gene id: 1121448:DGI_RS13495
uniprot id: T2GEV3
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS13410
gene id: 1121448:DGI_RS13410
uniprot id: T2GED6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1121448:DGI RS06170
gene id: 1121448:DGI_RS06170
uniprot id: T2GA54
names: Similarity
messages: Belongs to the HsdR family.

1121448:DGI RS08200
gene id: 1121448:DGI_RS08200
uniprot id: T2GBT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS15440
gene id: 1121448:DGI_RS15440
uniprot id: T2GEJ6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1121448:DGI RS13045
gene id: 1121448:DGI_RS13045
uniprot id: T2GDA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1121448:DGI RS16430
gene id: 1121448:DGI_RS16430
uniprot id: T2GGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS09685
gene id: 1121448:DGI_RS09685
uniprot id: T2GD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1121448:DGI RS06825
gene id: 1121448:DGI_RS06825
uniprot id: T2G9L7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1121448:DGI RS12335
gene id: 1121448:DGI_RS12335
uniprot id: T2GE02
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS02155
gene id: 1121448:DGI_RS02155
uniprot id: T2G899
names: Cofactor
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 [4Fe-4S] clusters.
messages: Consists of three sections from the N- to the C-terminus: [4Fe-4S] cluster-binding domain, beta-sheet and C-terminal tail. The beta-sheet and the C-terminal tail interact with AprA to stabilize the AprA/AprB heterodimer.
messages: Cytoplasm
messages: Heterodimer composed of AprA and AprB (PubMed:19820092, PubMed:2158885). The heterodimers can dimerize to form heterotetramers (PubMed:2158885).
messages: Iron-sulfur cluster subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction. The iron-sulfur cluster 2 is thought to accept electrons from a still unknown electron donor and transfer electrons to the iron-sulfur cluster 1 of this protein and then onto the FAD of AprA.

1121448:DGI RS08850
gene id: 1121448:DGI_RS08850
uniprot id: T2GC48
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1121448:DGI RS16665
gene id: 1121448:DGI_RS16665
uniprot id: T2GGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS13510
gene id: 1121448:DGI_RS13510
uniprot id: T2GEQ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1121448:DGI RS16330
gene id: 1121448:DGI_RS16330
uniprot id: T2GGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1121448:DGI RS09495
gene id: 1121448:DGI_RS09495
uniprot id: T2GBZ0
names: Similarity
messages: Belongs to the peptidase S14 family.

1121448:DGI RS06400
gene id: 1121448:DGI_RS06400
uniprot id: T2G9E2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1121448:DGI RS08275
gene id: 1121448:DGI_RS08275
uniprot id: T2GBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121448:DGI RS00255
gene id: 1121448:DGI_RS00255
uniprot id: T2G781
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1121448:DGI RS00140
gene id: 1121448:DGI_RS00140
uniprot id: T2G6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1121448:DGI RS05250
gene id: 1121448:DGI_RS05250
uniprot id: T2GA17
names: Similarity
messages: Belongs to the HypD family.

1121448:DGI RS06465
gene id: 1121448:DGI_RS06465
uniprot id: T2GAR8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1121448:DGI RS05425
gene id: 1121448:DGI_RS05425
uniprot id: T2GA53
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS15910
gene id: 1121448:DGI_RS15910
uniprot id: T2GG36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1121448:DGI RS04050
gene id: 1121448:DGI_RS04050
uniprot id: T2G9E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS00605
gene id: 1121448:DGI_RS00605
uniprot id: T2G871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1121448:DGI RS03600
gene id: 1121448:DGI_RS03600
uniprot id: T2G9T1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1121448:DGI RS06035
gene id: 1121448:DGI_RS06035
uniprot id: T2GAI5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1121448:DGI RS12865
gene id: 1121448:DGI_RS12865
uniprot id: T2GEA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS00150
gene id: 1121448:DGI_RS00150
uniprot id: T2G5W2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS10460
gene id: 1121448:DGI_RS10460
uniprot id: T2GDQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS16005
gene id: 1121448:DGI_RS16005
uniprot id: T2GF02
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121448:DGI RS09145
gene id: 1121448:DGI_RS09145
uniprot id: T2GCW8
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1121448:DGI RS12660
gene id: 1121448:DGI_RS12660
uniprot id: T2GDU2
names: Similarity
messages: Belongs to the glutamate synthase family.

1121448:DGI RS03390
gene id: 1121448:DGI_RS03390
uniprot id: T2G8L0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS10880
gene id: 1121448:DGI_RS10880
uniprot id: T2GCV4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121448:DGI RS08620
gene id: 1121448:DGI_RS08620
uniprot id: T2GC03
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS11695
gene id: 1121448:DGI_RS11695
uniprot id: T2GDM7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121448:DGI RS08380
gene id: 1121448:DGI_RS08380
uniprot id: T2GCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS02360
gene id: 1121448:DGI_RS02360
uniprot id: T2G8D9
names: Subcellular Location Annotation
messages: Cytoplasm

1121448:DGI RS15390
gene id: 1121448:DGI_RS15390
uniprot id: T2GEI6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1121448:DGI RS03235
gene id: 1121448:DGI_RS03235
uniprot id: T2G8I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1121448:DGI RS08095
gene id: 1121448:DGI_RS08095
uniprot id: T2GAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1121448:DGI RS05160
gene id: 1121448:DGI_RS05160
uniprot id: T2G9I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1121448:DGI RS02770
gene id: 1121448:DGI_RS02770
uniprot id: T2G8H8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS08760
gene id: 1121448:DGI_RS08760
uniprot id: T2GBL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121448:DGI RS12540
gene id: 1121448:DGI_RS12540
uniprot id: T2GCZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1121448:DGI RS12225
gene id: 1121448:DGI_RS12225
uniprot id: T2GEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS12755
gene id: 1121448:DGI_RS12755
uniprot id: T2GDW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1121448:DGI RS06950
gene id: 1121448:DGI_RS06950
uniprot id: T2G9P5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1121448:DGI RS13815
gene id: 1121448:DGI_RS13815
uniprot id: T2GEK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS12630
gene id: 1121448:DGI_RS12630
uniprot id: T2GEW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121448:DGI RS10050
gene id: 1121448:DGI_RS10050
uniprot id: T2GCP0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1121448:DGI RS12055
gene id: 1121448:DGI_RS12055
uniprot id: T2GEK1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121448:DGI RS11245
gene id: 1121448:DGI_RS11245
uniprot id: T2GDD9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1121448:DGI RS13605
gene id: 1121448:DGI_RS13605
uniprot id: T2GDL6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS14190
gene id: 1121448:DGI_RS14190
uniprot id: T2GEQ8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1121448:DGI RS09755
gene id: 1121448:DGI_RS09755
uniprot id: T2GBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121448:DGI RS10445
gene id: 1121448:DGI_RS10445
uniprot id: T2GCX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1121448:DGI RS04250
gene id: 1121448:DGI_RS04250
uniprot id: T2G9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121448:DGI RS13380
gene id: 1121448:DGI_RS13380
uniprot id: T2GFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS12145
gene id: 1121448:DGI_RS12145
uniprot id: T2GCR0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1121448:DGI RS08085
gene id: 1121448:DGI_RS08085
uniprot id: T2GB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1121448:DGI RS06675
gene id: 1121448:DGI_RS06675
uniprot id: T2G9J1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS02025
gene id: 1121448:DGI_RS02025
uniprot id: T2G874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1121448:DGI RS02125
gene id: 1121448:DGI_RS02125
uniprot id: T2G6Z6
names: Similarity
messages: Belongs to the UPF0434 family.

1121448:DGI RS16230
gene id: 1121448:DGI_RS16230
uniprot id: T2GG85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS07080
gene id: 1121448:DGI_RS07080
uniprot id: T2GBP5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07515
gene id: 1121448:DGI_RS07515
uniprot id: T2GBC0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS05745
gene id: 1121448:DGI_RS05745
uniprot id: T2GA88
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

1121448:DGI RS04035
gene id: 1121448:DGI_RS04035
uniprot id: T2G8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1121448:DGI RS13455
gene id: 1121448:DGI_RS13455
uniprot id: T2GFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS00185
gene id: 1121448:DGI_RS00185
uniprot id: T2G7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1121448:DGI RS13060
gene id: 1121448:DGI_RS13060
uniprot id: T2GE72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1121448:DGI RS07815
gene id: 1121448:DGI_RS07815
uniprot id: T2GBE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121448:DGI RS11595
gene id: 1121448:DGI_RS11595
uniprot id: T2GD72
names: Similarity
messages: Belongs to the thioredoxin family.

1121448:DGI RS14230
gene id: 1121448:DGI_RS14230
uniprot id: T2GF84
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1121448:DGI RS02100
gene id: 1121448:DGI_RS02100
uniprot id: T2G890
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS08305
gene id: 1121448:DGI_RS08305
uniprot id: T2GCH1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1121448:DGI RS11780
gene id: 1121448:DGI_RS11780
uniprot id: T2GDU4
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS06365
gene id: 1121448:DGI_RS06365
uniprot id: T2GBB6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1121448:DGI RS12670
gene id: 1121448:DGI_RS12670
uniprot id: T2GD17
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1121448:DGI RS12410
gene id: 1121448:DGI_RS12410
uniprot id: T2GE18
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS01500
gene id: 1121448:DGI_RS01500
uniprot id: T2G7I1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS13840
gene id: 1121448:DGI_RS13840
uniprot id: T2GEK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1121448:DGI RS03395
gene id: 1121448:DGI_RS03395
uniprot id: T2G8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1121448:DGI RS14300
gene id: 1121448:DGI_RS14300
uniprot id: T2GDY9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121448:DGI RS14735
gene id: 1121448:DGI_RS14735
uniprot id: T2GE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1121448:DGI RS06060
gene id: 1121448:DGI_RS06060
uniprot id: T2GAI9
names: Similarity
messages: Belongs to the P(II) protein family.

1121448:DGI RS08860
gene id: 1121448:DGI_RS08860
uniprot id: T2GBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS04730
gene id: 1121448:DGI_RS04730
uniprot id: T2G8F3
names: Similarity
messages: Belongs to the Fur family.

1121448:DGI RS16860
gene id: 1121448:DGI_RS16860
uniprot id: T2G903
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS13020
gene id: 1121448:DGI_RS13020
uniprot id: T2GD85
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1121448:DGI RS15895
gene id: 1121448:DGI_RS15895
uniprot id: T2GFR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1121448:DGI RS03095
gene id: 1121448:DGI_RS03095
uniprot id: T2G8W5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121448:DGI RS08240
gene id: 1121448:DGI_RS08240
uniprot id: T2GAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1121448:DGI RS05185
gene id: 1121448:DGI_RS05185
uniprot id: T2G9J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121448:DGI RS11345
gene id: 1121448:DGI_RS11345
uniprot id: T2GE76
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04040
gene id: 1121448:DGI_RS04040
uniprot id: T2G990
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS06680
gene id: 1121448:DGI_RS06680
uniprot id: T2GAW2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1121448:DGI RS06560
gene id: 1121448:DGI_RS06560
uniprot id: T2GAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121448:DGI RS16100
gene id: 1121448:DGI_RS16100
uniprot id: T2GF21
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1121448:DGI RS04900
gene id: 1121448:DGI_RS04900
uniprot id: T2G9D9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS06745
gene id: 1121448:DGI_RS06745
uniprot id: T2GAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121448:DGI RS06195
gene id: 1121448:DGI_RS06195
uniprot id: T2GAL7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1121448:DGI RS08145
gene id: 1121448:DGI_RS08145
uniprot id: T2GBN0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1121448:DGI RS09210
gene id: 1121448:DGI_RS09210
uniprot id: T2GB03
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1121448:DGI RS06530
gene id: 1121448:DGI_RS06530
uniprot id: T2G9G6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1121448:DGI RS15775
gene id: 1121448:DGI_RS15775
uniprot id: T2GGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS16070
gene id: 1121448:DGI_RS16070
uniprot id: T2GG22
names: Similarity
messages: Belongs to the LOG family.

1121448:DGI RS13335
gene id: 1121448:DGI_RS13335
uniprot id: T2GEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121448:DGI RS01090
gene id: 1121448:DGI_RS01090
uniprot id: T2G6H0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1121448:DGI RS12380
gene id: 1121448:DGI_RS12380
uniprot id: T2GDN4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1121448:DGI RS07910
gene id: 1121448:DGI_RS07910
uniprot id: T2GA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS19475
gene id: 1121448:DGI_RS19475
uniprot id: T2GDU5
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121448:DGI RS11135
gene id: 1121448:DGI_RS11135
uniprot id: T2GD01
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS15665
gene id: 1121448:DGI_RS15665
uniprot id: T2GG00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1121448:DGI RS07195
gene id: 1121448:DGI_RS07195
uniprot id: T2GB58
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1121448:DGI RS10255
gene id: 1121448:DGI_RS10255
uniprot id: T2GDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1121448:DGI RS18650
gene id: 1121448:DGI_RS18650
uniprot id: T2G971
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1121448:DGI RS08165
gene id: 1121448:DGI_RS08165
uniprot id: T2GBN5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1121448:DGI RS01080
gene id: 1121448:DGI_RS01080
uniprot id: T2G7B1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS06695
gene id: 1121448:DGI_RS06695
uniprot id: T2GAR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1121448:DGI RS04020
gene id: 1121448:DGI_RS04020
uniprot id: T2G828
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1121448:DGI RS16205
gene id: 1121448:DGI_RS16205
uniprot id: T2GG81
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1121448:DGI RS04920
gene id: 1121448:DGI_RS04920
uniprot id: T2GAF5
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121448:DGI RS10515
gene id: 1121448:DGI_RS10515
uniprot id: T2GCL8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121448:DGI RS06820
gene id: 1121448:DGI_RS06820
uniprot id: T2GAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1121448:DGI RS10040
gene id: 1121448:DGI_RS10040
uniprot id: T2GDF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1121448:DGI RS10740
gene id: 1121448:DGI_RS10740
uniprot id: T2GBZ7
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS09070
gene id: 1121448:DGI_RS09070
uniprot id: T2GBR2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12840
gene id: 1121448:DGI_RS12840
uniprot id: T2GD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1121448:DGI RS15915
gene id: 1121448:DGI_RS15915
uniprot id: T2GGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1121448:DGI RS04715
gene id: 1121448:DGI_RS04715
uniprot id: T2GAB7
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07560
gene id: 1121448:DGI_RS07560
uniprot id: T2GA14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1121448:DGI RS07405
gene id: 1121448:DGI_RS07405
uniprot id: T2GAU1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1121448:DGI RS07710
gene id: 1121448:DGI_RS07710
uniprot id: T2GC30
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1121448:DGI RS02975
gene id: 1121448:DGI_RS02975
uniprot id: T2G8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121448:DGI RS13805
gene id: 1121448:DGI_RS13805
uniprot id: T2GF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS08755
gene id: 1121448:DGI_RS08755
uniprot id: T2GCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS07900
gene id: 1121448:DGI_RS07900
uniprot id: T2GB39
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1121448:DGI RS13990
gene id: 1121448:DGI_RS13990
uniprot id: T2GEM5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS13330
gene id: 1121448:DGI_RS13330
uniprot id: T2GFD7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1121448:DGI RS14020
gene id: 1121448:DGI_RS14020
uniprot id: T2GF01
names: Similarity
messages: Belongs to the universal stress protein A family.

1121448:DGI RS10620
gene id: 1121448:DGI_RS10620
uniprot id: T2GD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1121448:DGI RS07705
gene id: 1121448:DGI_RS07705
uniprot id: T2GBG3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1121448:DGI RS09690
gene id: 1121448:DGI_RS09690
uniprot id: T2GC43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1121448:DGI RS06625
gene id: 1121448:DGI_RS06625
uniprot id: T2GAP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121448:DGI RS06375
gene id: 1121448:DGI_RS06375
uniprot id: T2GAJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1121448:DGI RS16160
gene id: 1121448:DGI_RS16160
uniprot id: T2GGH3
names: Similarity
messages: Belongs to the UPF0235 family.

1121448:DGI RS10475
gene id: 1121448:DGI_RS10475
uniprot id: T2GBR8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1121448:DGI RS06525
gene id: 1121448:DGI_RS06525
uniprot id: T2GAM3
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1121448:DGI RS06415
gene id: 1121448:DGI_RS06415
uniprot id: T2GA98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS15620
gene id: 1121448:DGI_RS15620
uniprot id: T2GGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1121448:DGI RS15235
gene id: 1121448:DGI_RS15235
uniprot id: T2GEF7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1121448:DGI RS11485
gene id: 1121448:DGI_RS11485
uniprot id: T2GCD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1121448:DGI RS02840
gene id: 1121448:DGI_RS02840
uniprot id: T2G891
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121448:DGI RS11865
gene id: 1121448:DGI_RS11865
uniprot id: T2GDC0
names: Similarity
messages: Belongs to the UPF0045 family.

1121448:DGI RS14820
gene id: 1121448:DGI_RS14820
uniprot id: T2GG10
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1121448:DGI RS13220
gene id: 1121448:DGI_RS13220
uniprot id: T2GDF0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1121448:DGI RS05670
gene id: 1121448:DGI_RS05670
uniprot id: T2GA75
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121448:DGI RS10785
gene id: 1121448:DGI_RS10785
uniprot id: T2GD62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1121448:DGI RS13040
gene id: 1121448:DGI_RS13040
uniprot id: T2GEE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1121448:DGI RS15745
gene id: 1121448:DGI_RS15745
uniprot id: T2GGF0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1121448:DGI RS13825
gene id: 1121448:DGI_RS13825
uniprot id: T2GDQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1121448:DGI RS03545
gene id: 1121448:DGI_RS03545
uniprot id: T2G948
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1121448:DGI RS13010
gene id: 1121448:DGI_RS13010
uniprot id: T2GE21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS01875
gene id: 1121448:DGI_RS01875
uniprot id: T2G6U8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1121448:DGI RS03130
gene id: 1121448:DGI_RS03130
uniprot id: T2G9J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1121448:DGI RS10425
gene id: 1121448:DGI_RS10425
uniprot id: T2GBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1121448:DGI RS15275
gene id: 1121448:DGI_RS15275
uniprot id: T2GFC4
names: Subunit
messages: Homotetramer.

1121448:DGI RS12175
gene id: 1121448:DGI_RS12175
uniprot id: T2GEL9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS15405
gene id: 1121448:DGI_RS15405
uniprot id: T2GFF3
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS06740
gene id: 1121448:DGI_RS06740
uniprot id: T2GAF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1121448:DGI RS13055
gene id: 1121448:DGI_RS13055
uniprot id: T2GF91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1121448:DGI RS12975
gene id: 1121448:DGI_RS12975
uniprot id: T2GEH6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1121448:DGI RS06815
gene id: 1121448:DGI_RS06815
uniprot id: T2GAG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS05625
gene id: 1121448:DGI_RS05625
uniprot id: T2G8X2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS08365
gene id: 1121448:DGI_RS08365
uniprot id: T2GBR1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1121448:DGI RS08300
gene id: 1121448:DGI_RS08300
uniprot id: T2GBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1121448:DGI RS09935
gene id: 1121448:DGI_RS09935
uniprot id: T2GDD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1121448:DGI RS07290
gene id: 1121448:DGI_RS07290
uniprot id: T2G9W0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1121448:DGI RS08155
gene id: 1121448:DGI_RS08155
uniprot id: T2GBS3
names: Similarity
messages: Belongs to the NodU/CmcH family.

1121448:DGI RS02465
gene id: 1121448:DGI_RS02465
uniprot id: T2G8G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121448:DGI RS05140
gene id: 1121448:DGI_RS05140
uniprot id: T2G9U2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1121448:DGI RS09970
gene id: 1121448:DGI_RS09970
uniprot id: T2GCA6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121448:DGI RS04235
gene id: 1121448:DGI_RS04235
uniprot id: T2G905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1121448:DGI RS11860
gene id: 1121448:DGI_RS11860
uniprot id: T2GEH0
names: Similarity
messages: Belongs to the GSP E family.

1121448:DGI RS03065
gene id: 1121448:DGI_RS03065
uniprot id: T2G7H8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121448:DGI RS06895
gene id: 1121448:DGI_RS06895
uniprot id: T2GAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS02090
gene id: 1121448:DGI_RS02090
uniprot id: T2G849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS12330
gene id: 1121448:DGI_RS12330
uniprot id: T2GDM4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121448:DGI RS12180
gene id: 1121448:DGI_RS12180
uniprot id: T2GDJ1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS01730
gene id: 1121448:DGI_RS01730
uniprot id: T2G8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1121448:DGI RS00515
gene id: 1121448:DGI_RS00515
uniprot id: T2G789
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1121448:DGI RS13595
gene id: 1121448:DGI_RS13595
uniprot id: T2GEG5
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1121448:DGI RS01365
gene id: 1121448:DGI_RS01365
uniprot id: T2G7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1121448:DGI RS10175
gene id: 1121448:DGI_RS10175
uniprot id: T2GCX3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1121448:DGI RS00895
gene id: 1121448:DGI_RS00895
uniprot id: T2G8C3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1121448:DGI RS00375
gene id: 1121448:DGI_RS00375
uniprot id: T2G806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1121448:DGI RS09645
gene id: 1121448:DGI_RS09645
uniprot id: T2GCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121448:DGI RS16000
gene id: 1121448:DGI_RS16000
uniprot id: T2GG09
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1121448:DGI RS15690
gene id: 1121448:DGI_RS15690
uniprot id: T2GG04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121448:DGI RS14900
gene id: 1121448:DGI_RS14900
uniprot id: T2GFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1121448:DGI RS02495
gene id: 1121448:DGI_RS02495
uniprot id: T2G943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1121448:DGI RS05505
gene id: 1121448:DGI_RS05505
uniprot id: T2GAT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS10600
gene id: 1121448:DGI_RS10600
uniprot id: T2GBX1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1121448:DGI RS02775
gene id: 1121448:DGI_RS02775
uniprot id: T2G7B5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS15845
gene id: 1121448:DGI_RS15845
uniprot id: T2GFQ5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1121448:DGI RS14715
gene id: 1121448:DGI_RS14715
uniprot id: T2GFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1121448:DGI RS11670
gene id: 1121448:DGI_RS11670
uniprot id: T2GD87
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1121448:DGI RS06715
gene id: 1121448:DGI_RS06715
uniprot id: T2GAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1121448:DGI RS00310
gene id: 1121448:DGI_RS00310
uniprot id: T2G6U7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1121448:DGI RS12810
gene id: 1121448:DGI_RS12810
uniprot id: T2GE92
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1121448:DGI RS12070
gene id: 1121448:DGI_RS12070
uniprot id: T2GCP6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121448:DGI RS09930
gene id: 1121448:DGI_RS09930
uniprot id: T2GCR9
names: Similarity
messages: Belongs to the GSP E family.

1121448:DGI RS10555
gene id: 1121448:DGI_RS10555
uniprot id: T2GD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1121448:DGI RS07890
gene id: 1121448:DGI_RS07890
uniprot id: T2GBK2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121448:DGI RS10170
gene id: 1121448:DGI_RS10170
uniprot id: T2GBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS03620
gene id: 1121448:DGI_RS03620
uniprot id: T2G963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS14145
gene id: 1121448:DGI_RS14145
uniprot id: T2GF27
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1121448:DGI RS12735
gene id: 1121448:DGI_RS12735
uniprot id: T2GDV8
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1121448:DGI RS12450
gene id: 1121448:DGI_RS12450
uniprot id: T2GES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1121448:DGI RS06360
gene id: 1121448:DGI_RS06360
uniprot id: T2GAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1121448:DGI RS09905
gene id: 1121448:DGI_RS09905
uniprot id: T2GCR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1121448:DGI RS13125
gene id: 1121448:DGI_RS13125
uniprot id: T2GEN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1121448:DGI RS13155
gene id: 1121448:DGI_RS13155
uniprot id: T2GFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS02530
gene id: 1121448:DGI_RS02530
uniprot id: T2G829
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121448:DGI RS03225
gene id: 1121448:DGI_RS03225
uniprot id: T2G8Y9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS13015
gene id: 1121448:DGI_RS13015
uniprot id: T2GED5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS05725
gene id: 1121448:DGI_RS05725
uniprot id: T2G913
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1121448:DGI RS07875
gene id: 1121448:DGI_RS07875
uniprot id: T2GB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

1121448:DGI RS04655
gene id: 1121448:DGI_RS04655
uniprot id: T2G8E1
names: Similarity
messages: Belongs to the RutC family.

1121448:DGI RS01405
gene id: 1121448:DGI_RS01405
uniprot id: T2G8K6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1121448:DGI RS00170
gene id: 1121448:DGI_RS00170
uniprot id: T2G705
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1121448:DGI RS14180
gene id: 1121448:DGI_RS14180
uniprot id: T2GF76
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1121448:DGI RS16730
gene id: 1121448:DGI_RS16730
uniprot id: T2G793
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1121448:DGI RS07030
gene id: 1121448:DGI_RS07030
uniprot id: T2GB24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1121448:DGI RS15955
gene id: 1121448:DGI_RS15955
uniprot id: T2GEZ2
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1121448:DGI RS13005
gene id: 1121448:DGI_RS13005
uniprot id: T2GF42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1121448:DGI RS15730
gene id: 1121448:DGI_RS15730
uniprot id: T2GFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1121448:DGI RS13765
gene id: 1121448:DGI_RS13765
uniprot id: T2GEJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121448:DGI RS01140
gene id: 1121448:DGI_RS01140
uniprot id: T2G6H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121448:DGI RS01735
gene id: 1121448:DGI_RS01735
uniprot id: T2G7L8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1121448:DGI RS07620
gene id: 1121448:DGI_RS07620
uniprot id: T2GAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1121448:DGI RS13080
gene id: 1121448:DGI_RS13080
uniprot id: T2GF95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1121448:DGI RS01250
gene id: 1121448:DGI_RS01250
uniprot id: T2G8H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121448:DGI RS10160
gene id: 1121448:DGI_RS10160
uniprot id: T2GCE1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1121448:DGI RS05825
gene id: 1121448:DGI_RS05825
uniprot id: T2GAA0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1121448:DGI RS02305
gene id: 1121448:DGI_RS02305
uniprot id: T2G723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1121448:DGI RS07200
gene id: 1121448:DGI_RS07200
uniprot id: T2GBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121448:DGI RS08190
gene id: 1121448:DGI_RS08190
uniprot id: T2GBP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1121448:DGI RS06880
gene id: 1121448:DGI_RS06880
uniprot id: T2GAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS07370
gene id: 1121448:DGI_RS07370
uniprot id: T2GB92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1121448:DGI RS11830
gene id: 1121448:DGI_RS11830
uniprot id: T2GDV3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1121448:DGI RS14740
gene id: 1121448:DGI_RS14740
uniprot id: T2GFI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1121448:DGI RS13640
gene id: 1121448:DGI_RS13640
uniprot id: T2GFJ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121448:DGI RS09825
gene id: 1121448:DGI_RS09825
uniprot id: T2GBD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1121448:DGI RS01625
gene id: 1121448:DGI_RS01625
uniprot id: T2G8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1121448:DGI RS12430
gene id: 1121448:DGI_RS12430
uniprot id: T2GDP6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1121448:DGI RS12880
gene id: 1121448:DGI_RS12880
uniprot id: T2GF13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1121448:DGI RS14525
gene id: 1121448:DGI_RS14525
uniprot id: T2GEX9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1121448:DGI RS07310
gene id: 1121448:DGI_RS07310
uniprot id: T2GB35
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

1121448:DGI RS14870
gene id: 1121448:DGI_RS14870
uniprot id: T2GE88
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1121448:DGI RS15240
gene id: 1121448:DGI_RS15240
uniprot id: T2GFR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1121448:DGI RS06885
gene id: 1121448:DGI_RS06885
uniprot id: T2GBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121448:DGI RS12375
gene id: 1121448:DGI_RS12375
uniprot id: T2GEQ4
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS14235
gene id: 1121448:DGI_RS14235
uniprot id: T2GFS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1121448:DGI RS00220
gene id: 1121448:DGI_RS00220
uniprot id: T2G717
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1121448:DGI RS14005
gene id: 1121448:DGI_RS14005
uniprot id: T2GF50
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1121448:DGI RS08890
gene id: 1121448:DGI_RS08890
uniprot id: T2GC00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1121448:DGI RS06430
gene id: 1121448:DGI_RS06430
uniprot id: T2G9E7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1121448:DGI RS14080
gene id: 1121448:DGI_RS14080
uniprot id: T2GF63
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07540
gene id: 1121448:DGI_RS07540
uniprot id: T2GBC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1121448:DGI RS14460
gene id: 1121448:DGI_RS14460
uniprot id: T2GE17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1121448:DGI RS16175
gene id: 1121448:DGI_RS16175
uniprot id: T2GF36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121448:DGI RS16340
gene id: 1121448:DGI_RS16340
uniprot id: T2GG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS11515
gene id: 1121448:DGI_RS11515
uniprot id: T2GDP5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1121448:DGI RS18750
gene id: 1121448:DGI_RS18750
uniprot id: T2GBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1121448:DGI RS05190
gene id: 1121448:DGI_RS05190
uniprot id: T2G9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121448:DGI RS08900
gene id: 1121448:DGI_RS08900
uniprot id: T2GC57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1121448:DGI RS07635
gene id: 1121448:DGI_RS07635
uniprot id: T2GBE6
names: Similarity
messages: Belongs to the peptidase M16 family.

1121448:DGI RS11980
gene id: 1121448:DGI_RS11980
uniprot id: T2GDY5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121448:DGI RS14030
gene id: 1121448:DGI_RS14030
uniprot id: T2GF54
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1121448:DGI RS13985
gene id: 1121448:DGI_RS13985
uniprot id: T2GFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121448:DGI RS17415
gene id: 1121448:DGI_RS17415
uniprot id: T2GF03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1121448:DGI RS08210
gene id: 1121448:DGI_RS08210
uniprot id: T2GBC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1121448:DGI RS13030
gene id: 1121448:DGI_RS13030
uniprot id: T2GF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1121448:DGI RS11255
gene id: 1121448:DGI_RS11255
uniprot id: T2GDK0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1121448:DGI RS15785
gene id: 1121448:DGI_RS15785
uniprot id: T2GFX6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07715
gene id: 1121448:DGI_RS07715
uniprot id: T2GB01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1121448:DGI RS01610
gene id: 1121448:DGI_RS01610
uniprot id: T2G7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1121448:DGI RS07010
gene id: 1121448:DGI_RS07010
uniprot id: T2GBN3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1121448:DGI RS01785
gene id: 1121448:DGI_RS01785
uniprot id: T2G7M8
names: Subunit
messages: Heterodimer of a large and a small subunit.

1121448:DGI RS13315
gene id: 1121448:DGI_RS13315
uniprot id: T2GEM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1121448:DGI RS01170
gene id: 1121448:DGI_RS01170
uniprot id: T2G7S4
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07180
gene id: 1121448:DGI_RS07180
uniprot id: T2GBR5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1121448:DGI RS12310
gene id: 1121448:DGI_RS12310
uniprot id: T2GDZ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1121448:DGI RS04150
gene id: 1121448:DGI_RS04150
uniprot id: T2G9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1121448:DGI RS03695
gene id: 1121448:DGI_RS03695
uniprot id: T2G978
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1121448:DGI RS03220
gene id: 1121448:DGI_RS03220
uniprot id: T2G7N3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1121448:DGI RS17615
gene id: 1121448:DGI_RS17615
uniprot id: T2GGA7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121448:DGI RS11680
gene id: 1121448:DGI_RS11680
uniprot id: T2GCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1121448:DGI RS02425
gene id: 1121448:DGI_RS02425
uniprot id: T2G8B3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1121448:DGI RS11510
gene id: 1121448:DGI_RS11510
uniprot id: T2GCD6
names: Similarity
messages: Belongs to the aspartokinase family.

1121448:DGI RS02390
gene id: 1121448:DGI_RS02390
uniprot id: T2G921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1121448:DGI RS03135
gene id: 1121448:DGI_RS03135
uniprot id: T2G8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1121448:DGI RS15700
gene id: 1121448:DGI_RS15700
uniprot id: T2GFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1121448:DGI RS13345
gene id: 1121448:DGI_RS13345
uniprot id: T2GDH2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12930
gene id: 1121448:DGI_RS12930
uniprot id: T2GF25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121448:DGI RS11705
gene id: 1121448:DGI_RS11705
uniprot id: T2GDT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1121448:DGI RS01630
gene id: 1121448:DGI_RS01630
uniprot id: T2G7K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS05935
gene id: 1121448:DGI_RS05935
uniprot id: T2GAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS09900
gene id: 1121448:DGI_RS09900
uniprot id: T2GBF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1121448:DGI RS02455
gene id: 1121448:DGI_RS02455
uniprot id: T2G8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1121448:DGI RS07565
gene id: 1121448:DGI_RS07565
uniprot id: T2GBZ5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1121448:DGI RS03160
gene id: 1121448:DGI_RS03160
uniprot id: T2G8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1121448:DGI RS04410
gene id: 1121448:DGI_RS04410
uniprot id: T2GA69
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121448:DGI RS12565
gene id: 1121448:DGI_RS12565
uniprot id: T2GE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1121448:DGI RS15935
gene id: 1121448:DGI_RS15935
uniprot id: T2GG40
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1121448:DGI RS15170
gene id: 1121448:DGI_RS15170
uniprot id: T2GFA1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1121448:DGI RS10340
gene id: 1121448:DGI_RS10340
uniprot id: T2GCV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS06230
gene id: 1121448:DGI_RS06230
uniprot id: T2GAG6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS05270
gene id: 1121448:DGI_RS05270
uniprot id: T2G8Q7
names: Similarity
messages: Belongs to the UbiD family.

1121448:DGI RS00940
gene id: 1121448:DGI_RS00940
uniprot id: T2G7N5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1121448:DGI RS08410
gene id: 1121448:DGI_RS08410
uniprot id: T2GC22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1121448:DGI RS10130
gene id: 1121448:DGI_RS10130
uniprot id: T2GCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1121448:DGI RS12095
gene id: 1121448:DGI_RS12095
uniprot id: T2GCQ1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1121448:DGI RS09835
gene id: 1121448:DGI_RS09835
uniprot id: T2GDB0
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS05410
gene id: 1121448:DGI_RS05410
uniprot id: T2G9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1121448:DGI RS10260
gene id: 1121448:DGI_RS10260
uniprot id: T2GCG3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1121448:DGI RS11100
gene id: 1121448:DGI_RS11100
uniprot id: T2GDH0
names: Subcellular Location Annotation
messages: Cytoplasm

1121448:DGI RS08375
gene id: 1121448:DGI_RS08375
uniprot id: T2GBL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121448:DGI RS14415
gene id: 1121448:DGI_RS14415
uniprot id: T2GFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1121448:DGI RS11635
gene id: 1121448:DGI_RS11635
uniprot id: T2GDS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1121448:DGI RS02450
gene id: 1121448:DGI_RS02450
uniprot id: T2G813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1121448:DGI RS02200
gene id: 1121448:DGI_RS02200
uniprot id: T2G708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS15115
gene id: 1121448:DGI_RS15115
uniprot id: T2GFN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121448:DGI RS06380
gene id: 1121448:DGI_RS06380
uniprot id: T2GAQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121448:DGI RS05530
gene id: 1121448:DGI_RS05530
uniprot id: T2G9S0
names: Similarity
messages: Belongs to the rubredoxin family.

1121448:DGI RS02875
gene id: 1121448:DGI_RS02875
uniprot id: T2G7D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121448:DGI RS00070
gene id: 1121448:DGI_RS00070
uniprot id: T2G5U7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS13070
gene id: 1121448:DGI_RS13070
uniprot id: T2GDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1121448:DGI RS14630
gene id: 1121448:DGI_RS14630
uniprot id: T2GE47
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1121448:DGI RS06045
gene id: 1121448:DGI_RS06045
uniprot id: T2GA32
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1121448:DGI RS02410
gene id: 1121448:DGI_RS02410
uniprot id: T2G8F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS03245
gene id: 1121448:DGI_RS03245
uniprot id: T2G7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1121448:DGI RS10655
gene id: 1121448:DGI_RS10655
uniprot id: T2GD91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1121448:DGI RS14475
gene id: 1121448:DGI_RS14475
uniprot id: T2GEW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1121448:DGI RS03690
gene id: 1121448:DGI_RS03690
uniprot id: T2G7W8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS05175
gene id: 1121448:DGI_RS05175
uniprot id: T2GA01
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1121448:DGI RS10650
gene id: 1121448:DGI_RS10650
uniprot id: T2GBY2
names: Similarity
messages: Belongs to the fabD family.

1121448:DGI RS14370
gene id: 1121448:DGI_RS14370
uniprot id: T2GEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1121448:DGI RS05210
gene id: 1121448:DGI_RS05210
uniprot id: T2G9J8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1121448:DGI RS04455
gene id: 1121448:DGI_RS04455
uniprot id: T2GA77
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1121448:DGI RS13025
gene id: 1121448:DGI_RS13025
uniprot id: T2GEJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1121448:DGI RS07095
gene id: 1121448:DGI_RS07095
uniprot id: T2G9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1121448:DGI RS06245
gene id: 1121448:DGI_RS06245
uniprot id: T2GB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1121448:DGI RS15195
gene id: 1121448:DGI_RS15195
uniprot id: T2GG68
names: Similarity
messages: Belongs to the ros/MucR family.

1121448:DGI RS04925
gene id: 1121448:DGI_RS04925
uniprot id: T2G9E3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1121448:DGI RS02690
gene id: 1121448:DGI_RS02690
uniprot id: T2G857
names: Similarity
messages: Belongs to the UPF0047 family.

1121448:DGI RS11825
gene id: 1121448:DGI_RS11825
uniprot id: T2GCK0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1121448:DGI RS16105
gene id: 1121448:DGI_RS16105
uniprot id: T2GG66
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1121448:DGI RS01615
gene id: 1121448:DGI_RS01615
uniprot id: T2G6Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1121448:DGI RS07305
gene id: 1121448:DGI_RS07305
uniprot id: T2GAS1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1121448:DGI RS07615
gene id: 1121448:DGI_RS07615
uniprot id: T2GC06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1121448:DGI RS03780
gene id: 1121448:DGI_RS03780
uniprot id: T2G9V8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121448:DGI RS18680
gene id: 1121448:DGI_RS18680
uniprot id: T2G9H6
names: Similarity
messages: Belongs to the MotB family.

1121448:DGI RS06935
gene id: 1121448:DGI_RS06935
uniprot id: T2GBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1121448:DGI RS06285
gene id: 1121448:DGI_RS06285
uniprot id: T2G9B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1121448:DGI RS12900
gene id: 1121448:DGI_RS12900
uniprot id: T2GEG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1121448:DGI RS07090
gene id: 1121448:DGI_RS07090
uniprot id: T2GAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1121448:DGI RS12885
gene id: 1121448:DGI_RS12885
uniprot id: T2GDZ3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1121448:DGI RS00400
gene id: 1121448:DGI_RS00400
uniprot id: T2G7B2
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07130
gene id: 1121448:DGI_RS07130
uniprot id: T2GBQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS03555
gene id: 1121448:DGI_RS03555
uniprot id: T2G8P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1121448:DGI RS03280
gene id: 1121448:DGI_RS03280
uniprot id: T2G9M7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1121448:DGI RS01255
gene id: 1121448:DGI_RS01255
uniprot id: T2G7E0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121448:DGI RS01965
gene id: 1121448:DGI_RS01965
uniprot id: T2G8U4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1121448:DGI RS15755
gene id: 1121448:DGI_RS15755
uniprot id: T2GFX3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121448:DGI RS15065
gene id: 1121448:DGI_RS15065
uniprot id: T2GFM9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1121448:DGI RS12435
gene id: 1121448:DGI_RS12435
uniprot id: T2GE24
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1121448:DGI RS12030
gene id: 1121448:DGI_RS12030
uniprot id: T2GEJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1121448:DGI RS10770
gene id: 1121448:DGI_RS10770
uniprot id: T2GDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1121448:DGI RS00090
gene id: 1121448:DGI_RS00090
uniprot id: T2G6Z0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1121448:DGI RS03205
gene id: 1121448:DGI_RS03205
uniprot id: T2G9L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1121448:DGI RS02860
gene id: 1121448:DGI_RS02860
uniprot id: T2G9C0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS02010
gene id: 1121448:DGI_RS02010
uniprot id: T2G868
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1121448:DGI RS01675
gene id: 1121448:DGI_RS01675
uniprot id: T2G8P9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1121448:DGI RS07385
gene id: 1121448:DGI_RS07385
uniprot id: T2GB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1121448:DGI RS14800
gene id: 1121448:DGI_RS14800
uniprot id: T2GF34
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121448:DGI RS10110
gene id: 1121448:DGI_RS10110
uniprot id: T2GCV6
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS04140
gene id: 1121448:DGI_RS04140
uniprot id: T2G9A7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS18460
gene id: 1121448:DGI_RS18460
uniprot id: T2GDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS03180
gene id: 1121448:DGI_RS03180
uniprot id: T2G9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1121448:DGI RS04025
gene id: 1121448:DGI_RS04025
uniprot id: T2G9E0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1121448:DGI RS09730
gene id: 1121448:DGI_RS09730
uniprot id: T2GCN1
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS07415
gene id: 1121448:DGI_RS07415
uniprot id: T2G9Y3
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS13970
gene id: 1121448:DGI_RS13970
uniprot id: T2GEZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS07475
gene id: 1121448:DGI_RS07475
uniprot id: T2GAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1121448:DGI RS13745
gene id: 1121448:DGI_RS13745
uniprot id: T2GEU8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121448:DGI RS13210
gene id: 1121448:DGI_RS13210
uniprot id: T2GE99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1121448:DGI RS09150
gene id: 1121448:DGI_RS09150
uniprot id: T2GBS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1121448:DGI RS08960
gene id: 1121448:DGI_RS08960
uniprot id: T2GC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS10565
gene id: 1121448:DGI_RS10565
uniprot id: T2GCP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1121448:DGI RS09130
gene id: 1121448:DGI_RS09130
uniprot id: T2GAZ0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1121448:DGI RS17050
gene id: 1121448:DGI_RS17050
uniprot id: T2GAN9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS12765
gene id: 1121448:DGI_RS12765
uniprot id: T2GD37
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS16180
gene id: 1121448:DGI_RS16180
uniprot id: T2GG77
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS07340
gene id: 1121448:DGI_RS07340
uniprot id: T2GB40
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1121448:DGI RS04760
gene id: 1121448:DGI_RS04760
uniprot id: T2G9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1121448:DGI RS16280
gene id: 1121448:DGI_RS16280
uniprot id: T2GG90
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1121448:DGI RS10080
gene id: 1121448:DGI_RS10080
uniprot id: T2GBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1121448:DGI RS11130
gene id: 1121448:DGI_RS11130
uniprot id: T2GE46
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1121448:DGI RS11420
gene id: 1121448:DGI_RS11420
uniprot id: T2GE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121448:DGI RS13095
gene id: 1121448:DGI_RS13095
uniprot id: T2GDC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1121448:DGI RS08360
gene id: 1121448:DGI_RS08360
uniprot id: T2GBE5
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS00680
gene id: 1121448:DGI_RS00680
uniprot id: T2G752
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1121448:DGI RS10560
gene id: 1121448:DGI_RS10560
uniprot id: T2GDU7
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1121448:DGI RS14205
gene id: 1121448:DGI_RS14205
uniprot id: T2GF80
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1121448:DGI RS15425
gene id: 1121448:DGI_RS15425
uniprot id: T2GGA2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1121448:DGI RS08675
gene id: 1121448:DGI_RS08675
uniprot id: T2GC13
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1121448:DGI RS06390
gene id: 1121448:DGI_RS06390
uniprot id: T2GA94
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121448:DGI RS06620
gene id: 1121448:DGI_RS06620
uniprot id: T2GAD1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121448:DGI RS07440
gene id: 1121448:DGI_RS07440
uniprot id: T2G9Y9
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1121448:DGI RS02380
gene id: 1121448:DGI_RS02380
uniprot id: T2G738
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1121448:DGI RS13090
gene id: 1121448:DGI_RS13090
uniprot id: T2GEJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1121448:DGI RS16055
gene id: 1121448:DGI_RS16055
uniprot id: T2GF12
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121448:DGI RS04305
gene id: 1121448:DGI_RS04305
uniprot id: T2GA52
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121448:DGI RS04175
gene id: 1121448:DGI_RS04175
uniprot id: T2G9G7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121448:DGI RS06580
gene id: 1121448:DGI_RS06580
uniprot id: T2G9H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1121448:DGI RS08770
gene id: 1121448:DGI_RS08770
uniprot id: T2GBR1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1121448:DGI RS12995
gene id: 1121448:DGI_RS12995
uniprot id: T2GD80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1121448:DGI RS02835
gene id: 1121448:DGI_RS02835
uniprot id: T2G9B5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1121448:DGI RS00110
gene id: 1121448:DGI_RS00110
uniprot id: T2G7U5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1121448:DGI RS12025
gene id: 1121448:DGI_RS12025
uniprot id: T2GDZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1121448:DGI RS01595
gene id: 1121448:DGI_RS01595
uniprot id: T2G8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1121448:DGI RS08650
gene id: 1121448:DGI_RS08650
uniprot id: T2GCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1121448:DGI RS11120
gene id: 1121448:DGI_RS11120
uniprot id: T2GC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1121448:DGI RS09370
gene id: 1121448:DGI_RS09370
uniprot id: T2GC96
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1121448:DGI RS03270
gene id: 1121448:DGI_RS03270
uniprot id: T2G7P2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1121448:DGI RS04210
gene id: 1121448:DGI_RS04210
uniprot id: T2G900
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121448:DGI RS11870
gene id: 1121448:DGI_RS11870
uniprot id: T2GDR0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1121448:DGI RS09180
gene id: 1121448:DGI_RS09180
uniprot id: T2GC58
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1121448:DGI RS10165
gene id: 1121448:DGI_RS10165
uniprot id: T2GCR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121448:DGI RS06565
gene id: 1121448:DGI_RS06565
uniprot id: T2GBF4
names: Similarity
messages: Belongs to the Ahb/Nir family.

1121448:DGI RS15715
gene id: 1121448:DGI_RS15715
uniprot id: T2GG08
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1121448:DGI RS14490
gene id: 1121448:DGI_RS14490
uniprot id: T2GFD1
names: Similarity
messages: Belongs to the AOR/FOR family.

1121448:DGI RS13795
gene id: 1121448:DGI_RS13795
uniprot id: T2GEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121448:DGI RS01980
gene id: 1121448:DGI_RS01980
uniprot id: T2G6W6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1121448:DGI RS09870
gene id: 1121448:DGI_RS09870
uniprot id: T2GCK6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1121448:DGI RS10750
gene id: 1121448:DGI_RS10750
uniprot id: T2GDX8
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS11560
gene id: 1121448:DGI_RS11560
uniprot id: T2GDQ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121448:DGI RS12665
gene id: 1121448:DGI_RS12665
uniprot id: T2GE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1121448:DGI RS12140
gene id: 1121448:DGI_RS12140
uniprot id: T2GDW2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1121448:DGI RS01940
gene id: 1121448:DGI_RS01940
uniprot id: T2G8T9
names: Subcellular Location Annotation
messages: Membrane

1121448:DGI RS15260
gene id: 1121448:DGI_RS15260
uniprot id: T2GEG1
names: Subcellular Location Annotation
messages: Membrane