1112:A9D12 RS05065
gene id: 1112:A9D12_RS05065
uniprot id: A0A192D1P6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1112:A9D12 RS07635
gene id: 1112:A9D12_RS07635
uniprot id: A0A192D8J6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1112:A9D12 RS13995
gene id: 1112:A9D12_RS13995
uniprot id: A0A192D782
names: Similarity
messages: Belongs to the TlyA family.

1112:A9D12 RS10700
gene id: 1112:A9D12_RS10700
uniprot id: A0A192D4D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1112:A9D12 RS12145
gene id: 1112:A9D12_RS12145
uniprot id: A0A192D715
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1112:A9D12 RS12450
gene id: 1112:A9D12_RS12450
uniprot id: A0A192D9A5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS11810
gene id: 1112:A9D12_RS11810
uniprot id: A0A192D657
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1112:A9D12 RS03705
gene id: 1112:A9D12_RS03705
uniprot id: A0A192D2H0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1112:A9D12 RS00830
gene id: 1112:A9D12_RS00830
uniprot id: A0A192D1W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1112:A9D12 RS13450
gene id: 1112:A9D12_RS13450
uniprot id: A0A192D5L3
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1112:A9D12 RS14045
gene id: 1112:A9D12_RS14045
uniprot id: A0A192D794
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1112:A9D12 RS07275
gene id: 1112:A9D12_RS07275
uniprot id: A0A192D2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1112:A9D12 RS01115
gene id: 1112:A9D12_RS01115
uniprot id: A0A192D203
names: Similarity
messages: Belongs to the BolA/IbaG family.

1112:A9D12 RS10455
gene id: 1112:A9D12_RS10455
uniprot id: A0A192D5J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1112:A9D12 RS11915
gene id: 1112:A9D12_RS11915
uniprot id: A0A192D666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1112:A9D12 RS02855
gene id: 1112:A9D12_RS02855
uniprot id: A0A192D1P4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1112:A9D12 RS05620
gene id: 1112:A9D12_RS05620
uniprot id: A0A192D3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1112:A9D12 RS11175
gene id: 1112:A9D12_RS11175
uniprot id: A0A192D6B9
names: Similarity
messages: Belongs to the peptidase U62 family.

1112:A9D12 RS11455
gene id: 1112:A9D12_RS11455
uniprot id: A0A192D6Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS07910
gene id: 1112:A9D12_RS07910
uniprot id: A0A192D320
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12550
gene id: 1112:A9D12_RS12550
uniprot id: A0A192D565
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS11140
gene id: 1112:A9D12_RS11140
uniprot id: A0A192D6B4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1112:A9D12 RS01995
gene id: 1112:A9D12_RS01995
uniprot id: A0A192D1B2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS10585
gene id: 1112:A9D12_RS10585
uniprot id: A0A192D606
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1112:A9D12 RS10870
gene id: 1112:A9D12_RS10870
uniprot id: A0A192D6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1112:A9D12 RS12795
gene id: 1112:A9D12_RS12795
uniprot id: A0A192D6L5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1112:A9D12 RS04265
gene id: 1112:A9D12_RS04265
uniprot id: A0A192D2Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1112:A9D12 RS09580
gene id: 1112:A9D12_RS09580
uniprot id: A0A192D912
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1112:A9D12 RS06265
gene id: 1112:A9D12_RS06265
uniprot id: A0A192D3Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1112:A9D12 RS05590
gene id: 1112:A9D12_RS05590
uniprot id: A0A192D1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS14020
gene id: 1112:A9D12_RS14020
uniprot id: A0A192D787
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1112:A9D12 RS03155
gene id: 1112:A9D12_RS03155
uniprot id: A0A192D2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1112:A9D12 RS00100
gene id: 1112:A9D12_RS00100
uniprot id: A0A192D0Y3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1112:A9D12 RS11105
gene id: 1112:A9D12_RS11105
uniprot id: A0A192D6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS07020
gene id: 1112:A9D12_RS07020
uniprot id: A0A192D4C1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1112:A9D12 RS13245
gene id: 1112:A9D12_RS13245
uniprot id: A0A192D7K7
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1112:A9D12 RS06290
gene id: 1112:A9D12_RS06290
uniprot id: A0A192D3D9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1112:A9D12 RS00735
gene id: 1112:A9D12_RS00735
uniprot id: A0A192D1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS06900
gene id: 1112:A9D12_RS06900
uniprot id: A0A192D4A2
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12675
gene id: 1112:A9D12_RS12675
uniprot id: A0A192D6B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS11695
gene id: 1112:A9D12_RS11695
uniprot id: A0A192D6J7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1112:A9D12 RS04245
gene id: 1112:A9D12_RS04245
uniprot id: A0A192D1A0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS03550
gene id: 1112:A9D12_RS03550
uniprot id: A0A192D2K1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS02815
gene id: 1112:A9D12_RS02815
uniprot id: A0A192D0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1112:A9D12 RS03105
gene id: 1112:A9D12_RS03105
uniprot id: A0A192D8G1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1112:A9D12 RS02315
gene id: 1112:A9D12_RS02315
uniprot id: A0A192D1V8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS02670
gene id: 1112:A9D12_RS02670
uniprot id: A0A192D0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS05165
gene id: 1112:A9D12_RS05165
uniprot id: A0A192D3U7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1112:A9D12 RS07780
gene id: 1112:A9D12_RS07780
uniprot id: A0A192D4B4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS10255
gene id: 1112:A9D12_RS10255
uniprot id: A0A192D459
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1112:A9D12 RS06705
gene id: 1112:A9D12_RS06705
uniprot id: A0A192D2H6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1112:A9D12 RS10705
gene id: 1112:A9D12_RS10705
uniprot id: A0A192D6D3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1112:A9D12 RS06060
gene id: 1112:A9D12_RS06060
uniprot id: A0A192D488
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1112:A9D12 RS12900
gene id: 1112:A9D12_RS12900
uniprot id: A0A192D5C1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1112:A9D12 RS01170
gene id: 1112:A9D12_RS01170
uniprot id: A0A192D1E2
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1112:A9D12 RS12100
gene id: 1112:A9D12_RS12100
uniprot id: A0A192D697
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1112:A9D12 RS06880
gene id: 1112:A9D12_RS06880
uniprot id: A0A192D4K7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS01875
gene id: 1112:A9D12_RS01875
uniprot id: A0A192D066
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1112:A9D12 RS08100
gene id: 1112:A9D12_RS08100
uniprot id: A0A192D351
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1112:A9D12 RS13705
gene id: 1112:A9D12_RS13705
uniprot id: A0A192D728
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1112:A9D12 RS09935
gene id: 1112:A9D12_RS09935
uniprot id: A0A192D8S6
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1112:A9D12 RS01980
gene id: 1112:A9D12_RS01980
uniprot id: A0A192D1T9
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1112:A9D12 RS06700
gene id: 1112:A9D12_RS06700
uniprot id: A0A192D449
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS12480
gene id: 1112:A9D12_RS12480
uniprot id: A0A192D6G4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1112:A9D12 RS03940
gene id: 1112:A9D12_RS03940
uniprot id: A0A192D2K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1112:A9D12 RS13845
gene id: 1112:A9D12_RS13845
uniprot id: A0A192D7L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1112:A9D12 RS13495
gene id: 1112:A9D12_RS13495
uniprot id: A0A192D6Z0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1112:A9D12 RS08615
gene id: 1112:A9D12_RS08615
uniprot id: A0A192D3D5
names: Similarity
messages: Belongs to the bacterial secretin family.

1112:A9D12 RS02050
gene id: 1112:A9D12_RS02050
uniprot id: A0A192D2E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1112:A9D12 RS13035
gene id: 1112:A9D12_RS13035
uniprot id: A0A192D5E7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1112:A9D12 RS04535
gene id: 1112:A9D12_RS04535
uniprot id: A0A192D3K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1112:A9D12 RS11740
gene id: 1112:A9D12_RS11740
uniprot id: A0A192D991
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.

1112:A9D12 RS12680
gene id: 1112:A9D12_RS12680
uniprot id: A0A192D8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS12855
gene id: 1112:A9D12_RS12855
uniprot id: A0A192D6E7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1112:A9D12 RS09680
gene id: 1112:A9D12_RS09680
uniprot id: A0A192D5X0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS08540
gene id: 1112:A9D12_RS08540
uniprot id: A0A192D5C0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1112:A9D12 RS11935
gene id: 1112:A9D12_RS11935
uniprot id: A0A192D600
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1112:A9D12 RS11545
gene id: 1112:A9D12_RS11545
uniprot id: A0A192D6R6
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12400
gene id: 1112:A9D12_RS12400
uniprot id: A0A192D759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1112:A9D12 RS00255
gene id: 1112:A9D12_RS00255
uniprot id: A0A192D107
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1112:A9D12 RS13425
gene id: 1112:A9D12_RS13425
uniprot id: A0A192D5K9
names: Similarity
messages: Belongs to the TrpF family.

1112:A9D12 RS00370
gene id: 1112:A9D12_RS00370
uniprot id: A0A192D122
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1112:A9D12 RS07320
gene id: 1112:A9D12_RS07320
uniprot id: A0A192D440
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1112:A9D12 RS11440
gene id: 1112:A9D12_RS11440
uniprot id: A0A192D5Z7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1112:A9D12 RS13160
gene id: 1112:A9D12_RS13160
uniprot id: A0A192D788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1112:A9D12 RS06475
gene id: 1112:A9D12_RS06475
uniprot id: A0A192D4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1112:A9D12 RS13985
gene id: 1112:A9D12_RS13985
uniprot id: A0A192D7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1112:A9D12 RS12670
gene id: 1112:A9D12_RS12670
uniprot id: A0A192D7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS09685
gene id: 1112:A9D12_RS09685
uniprot id: A0A192D513
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1112:A9D12 RS08485
gene id: 1112:A9D12_RS08485
uniprot id: A0A192D5B0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1112:A9D12 RS12195
gene id: 1112:A9D12_RS12195
uniprot id: A0A192D504
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1112:A9D12 RS02960
gene id: 1112:A9D12_RS02960
uniprot id: A0A192D7Q1
names: Similarity
messages: Belongs to the UPF0145 family.

1112:A9D12 RS13760
gene id: 1112:A9D12_RS13760
uniprot id: A0A192D738
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1112:A9D12 RS09180
gene id: 1112:A9D12_RS09180
uniprot id: A0A192D5L9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1112:A9D12 RS03905
gene id: 1112:A9D12_RS03905
uniprot id: A0A192D2K3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS09210
gene id: 1112:A9D12_RS09210
uniprot id: A0A192D5M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1112:A9D12 RS05985
gene id: 1112:A9D12_RS05985
uniprot id: A0A192D389
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1112:A9D12 RS04625
gene id: 1112:A9D12_RS04625
uniprot id: A0A192D340
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1112:A9D12 RS07795
gene id: 1112:A9D12_RS07795
uniprot id: A0A192D509
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS06870
gene id: 1112:A9D12_RS06870
uniprot id: A0A192D497
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1112:A9D12 RS09770
gene id: 1112:A9D12_RS09770
uniprot id: A0A192D529
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS04580
gene id: 1112:A9D12_RS04580
uniprot id: A0A192D1G0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1112:A9D12 RS09650
gene id: 1112:A9D12_RS09650
uniprot id: A0A192D5W5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1112:A9D12 RS13345
gene id: 1112:A9D12_RS13345
uniprot id: A0A192D7C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1112:A9D12 RS11785
gene id: 1112:A9D12_RS11785
uniprot id: A0A192D652
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1112:A9D12 RS12255
gene id: 1112:A9D12_RS12255
uniprot id: A0A192D735
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1112:A9D12 RS10075
gene id: 1112:A9D12_RS10075
uniprot id: A0A192D575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS10865
gene id: 1112:A9D12_RS10865
uniprot id: A0A192D8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS02385
gene id: 1112:A9D12_RS02385
uniprot id: A0A192D1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1112:A9D12 RS02615
gene id: 1112:A9D12_RS02615
uniprot id: A0A192D1Z9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1112:A9D12 RS09240
gene id: 1112:A9D12_RS09240
uniprot id: A0A192D3P8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS06315
gene id: 1112:A9D12_RS06315
uniprot id: A0A192D4C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1112:A9D12 RS10660
gene id: 1112:A9D12_RS10660
uniprot id: A0A192D5H0
names: Similarity
messages: Belongs to the TPP enzyme family.

1112:A9D12 RS14330
gene id: 1112:A9D12_RS14330
uniprot id: A0A192D7E5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1112:A9D12 RS03775
gene id: 1112:A9D12_RS03775
uniprot id: A0A192D368
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1112:A9D12 RS08865
gene id: 1112:A9D12_RS08865
uniprot id: A0A192D4T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1112:A9D12 RS00285
gene id: 1112:A9D12_RS00285
uniprot id: A0A192CZG3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1112:A9D12 RS06805
gene id: 1112:A9D12_RS06805
uniprot id: A0A192D3V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1112:A9D12 RS12385
gene id: 1112:A9D12_RS12385
uniprot id: A0A192D906
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1112:A9D12 RS06790
gene id: 1112:A9D12_RS06790
uniprot id: A0A192D8S2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1112:A9D12 RS10600
gene id: 1112:A9D12_RS10600
uniprot id: A0A192D5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS04935
gene id: 1112:A9D12_RS04935
uniprot id: A0A192D3R0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1112:A9D12 RS13665
gene id: 1112:A9D12_RS13665
uniprot id: A0A192D7T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1112:A9D12 RS09645
gene id: 1112:A9D12_RS09645
uniprot id: A0A192D3W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1112:A9D12 RS00290
gene id: 1112:A9D12_RS00290
uniprot id: A0A192D1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1112:A9D12 RS11950
gene id: 1112:A9D12_RS11950
uniprot id: A0A192D4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1112:A9D12 RS09350
gene id: 1112:A9D12_RS09350
uniprot id: A0A192D8Q6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1112:A9D12 RS13800
gene id: 1112:A9D12_RS13800
uniprot id: A0A192D7V8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS00005
gene id: 1112:A9D12_RS00005
uniprot id: A0A192D7W2
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS04110
gene id: 1112:A9D12_RS04110
uniprot id: A0A192D2V0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1112:A9D12 RS03085
gene id: 1112:A9D12_RS03085
uniprot id: A0A192D2C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1112:A9D12 RS05445
gene id: 1112:A9D12_RS05445
uniprot id: A0A192D1W2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS09265
gene id: 1112:A9D12_RS09265
uniprot id: A0A192D5C9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1112:A9D12 RS13910
gene id: 1112:A9D12_RS13910
uniprot id: A0A192D6Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1112:A9D12 RS10545
gene id: 1112:A9D12_RS10545
uniprot id: A0A192D5K8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08645
gene id: 1112:A9D12_RS08645
uniprot id: A0A192D5E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1112:A9D12 RS12360
gene id: 1112:A9D12_RS12360
uniprot id: A0A192D6V7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1112:A9D12 RS13415
gene id: 1112:A9D12_RS13415
uniprot id: A0A192D7D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1112:A9D12 RS13710
gene id: 1112:A9D12_RS13710
uniprot id: A0A192D7J5
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1112:A9D12 RS08320
gene id: 1112:A9D12_RS08320
uniprot id: A0A192D4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS01290
gene id: 1112:A9D12_RS01290
uniprot id: A0A192D802
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1112:A9D12 RS13095
gene id: 1112:A9D12_RS13095
uniprot id: A0A192D781
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1112:A9D12 RS12210
gene id: 1112:A9D12_RS12210
uniprot id: A0A192D6B8
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS09525
gene id: 1112:A9D12_RS09525
uniprot id: A0A192D4Y8
names: Similarity
messages: Belongs to the GSP E family.

1112:A9D12 RS09720
gene id: 1112:A9D12_RS09720
uniprot id: A0A192D564
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1112:A9D12 RS07470
gene id: 1112:A9D12_RS07470
uniprot id: A0A192D3X2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1112:A9D12 RS02890
gene id: 1112:A9D12_RS02890
uniprot id: A0A192D283
names: Similarity
messages: Belongs to the HIBADH-related family.

1112:A9D12 RS08665
gene id: 1112:A9D12_RS08665
uniprot id: A0A192D3E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS04465
gene id: 1112:A9D12_RS04465
uniprot id: A0A192D311
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1112:A9D12 RS11800
gene id: 1112:A9D12_RS11800
uniprot id: A0A192D6V3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1112:A9D12 RS05845
gene id: 1112:A9D12_RS05845
uniprot id: A0A192D8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1112:A9D12 RS05045
gene id: 1112:A9D12_RS05045
uniprot id: A0A192D3S9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1112:A9D12 RS01550
gene id: 1112:A9D12_RS01550
uniprot id: A0A192D120
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1112:A9D12 RS04995
gene id: 1112:A9D12_RS04995
uniprot id: A0A192D2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1112:A9D12 RS08240
gene id: 1112:A9D12_RS08240
uniprot id: A0A192D576
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1112:A9D12 RS00535
gene id: 1112:A9D12_RS00535
uniprot id: A0A192D152
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS14025
gene id: 1112:A9D12_RS14025
uniprot id: A0A192D7Q4
names: Similarity
messages: Belongs to the pirin family.

1112:A9D12 RS01955
gene id: 1112:A9D12_RS01955
uniprot id: A0A192D1A7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1112:A9D12 RS01580
gene id: 1112:A9D12_RS01580
uniprot id: A0A192D1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1112:A9D12 RS14050
gene id: 1112:A9D12_RS14050
uniprot id: A0A192D7Q9
names: Similarity
messages: Belongs to the GST superfamily.

1112:A9D12 RS01850
gene id: 1112:A9D12_RS01850
uniprot id: A0A192D2B4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1112:A9D12 RS11660
gene id: 1112:A9D12_RS11660
uniprot id: A0A192D6J2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1112:A9D12 RS02895
gene id: 1112:A9D12_RS02895
uniprot id: A0A192D7G1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1112:A9D12 RS00695
gene id: 1112:A9D12_RS00695
uniprot id: A0A192D173
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS13080
gene id: 1112:A9D12_RS13080
uniprot id: A0A192D6S0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1112:A9D12 RS06695
gene id: 1112:A9D12_RS06695
uniprot id: A0A192D3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS14100
gene id: 1112:A9D12_RS14100
uniprot id: A0A192D722
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1112:A9D12 RS13885
gene id: 1112:A9D12_RS13885
uniprot id: A0A192D6Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS07160
gene id: 1112:A9D12_RS07160
uniprot id: A0A192D4Q1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1112:A9D12 RS08815
gene id: 1112:A9D12_RS08815
uniprot id: A0A192D5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1112:A9D12 RS13545
gene id: 1112:A9D12_RS13545
uniprot id: A0A192D7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1112:A9D12 RS04770
gene id: 1112:A9D12_RS04770
uniprot id: A0A192D1I7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS07970
gene id: 1112:A9D12_RS07970
uniprot id: A0A192D330
names: Similarity
messages: Belongs to the HsdR family.

1112:A9D12 RS13905
gene id: 1112:A9D12_RS13905
uniprot id: A0A192D7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1112:A9D12 RS01010
gene id: 1112:A9D12_RS01010
uniprot id: A0A192D1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1112:A9D12 RS10570
gene id: 1112:A9D12_RS10570
uniprot id: A0A192D5F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS04135
gene id: 1112:A9D12_RS04135
uniprot id: A0A192D2V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1112:A9D12 RS09630
gene id: 1112:A9D12_RS09630
uniprot id: A0A192D5J0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1112:A9D12 RS12175
gene id: 1112:A9D12_RS12175
uniprot id: A0A192D643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1112:A9D12 RS07245
gene id: 1112:A9D12_RS07245
uniprot id: A0A192D4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1112:A9D12 RS04865
gene id: 1112:A9D12_RS04865
uniprot id: A0A192D8K6
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS03040
gene id: 1112:A9D12_RS03040
uniprot id: A0A192D0P3
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS01310
gene id: 1112:A9D12_RS01310
uniprot id: A0A192D231
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1112:A9D12 RS08345
gene id: 1112:A9D12_RS08345
uniprot id: A0A192D4Y2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS04815
gene id: 1112:A9D12_RS04815
uniprot id: A0A192D2P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS05815
gene id: 1112:A9D12_RS05815
uniprot id: A0A192D364
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1112:A9D12 RS03170
gene id: 1112:A9D12_RS03170
uniprot id: A0A192D2E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1112:A9D12 RS07395
gene id: 1112:A9D12_RS07395
uniprot id: A0A192D4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1112:A9D12 RS08970
gene id: 1112:A9D12_RS08970
uniprot id: A0A192D4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS05405
gene id: 1112:A9D12_RS05405
uniprot id: A0A192D2Y9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS07385
gene id: 1112:A9D12_RS07385
uniprot id: A0A192D450
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1112:A9D12 RS02440
gene id: 1112:A9D12_RS02440
uniprot id: A0A192D2J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1112:A9D12 RS10625
gene id: 1112:A9D12_RS10625
uniprot id: A0A192D6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1112:A9D12 RS09140
gene id: 1112:A9D12_RS09140
uniprot id: A0A192D5L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1112:A9D12 RS06710
gene id: 1112:A9D12_RS06710
uniprot id: A0A192D4I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS12405
gene id: 1112:A9D12_RS12405
uniprot id: A0A192D673
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1112:A9D12 RS13625
gene id: 1112:A9D12_RS13625
uniprot id: A0A192D7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1112:A9D12 RS00630
gene id: 1112:A9D12_RS00630
uniprot id: A0A192D165
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS04555
gene id: 1112:A9D12_RS04555
uniprot id: A0A192D1F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1112:A9D12 RS08535
gene id: 1112:A9D12_RS08535
uniprot id: A0A192D3B9
names: Similarity
messages: Belongs to the peptidase M16 family.

1112:A9D12 RS11910
gene id: 1112:A9D12_RS11910
uniprot id: A0A192D5Z5
names: Similarity
messages: Belongs to the MreC family.

1112:A9D12 RS09405
gene id: 1112:A9D12_RS09405
uniprot id: A0A192D4W8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1112:A9D12 RS13615
gene id: 1112:A9D12_RS13615
uniprot id: A0A192D6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS06340
gene id: 1112:A9D12_RS06340
uniprot id: A0A192D4D2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1112:A9D12 RS05025
gene id: 1112:A9D12_RS05025
uniprot id: A0A192D343
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS10710
gene id: 1112:A9D12_RS10710
uniprot id: A0A192D5H9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1112:A9D12 RS12975
gene id: 1112:A9D12_RS12975
uniprot id: A0A192D761
names: Similarity
messages: Belongs to the DNA photolyase family.

1112:A9D12 RS12700
gene id: 1112:A9D12_RS12700
uniprot id: A0A192D7B2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1112:A9D12 RS01960
gene id: 1112:A9D12_RS01960
uniprot id: A0A192D1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1112:A9D12 RS13880
gene id: 1112:A9D12_RS13880
uniprot id: A0A192D7X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1112:A9D12 RS11500
gene id: 1112:A9D12_RS11500
uniprot id: A0A192D607
names: Cofactor
messages: Can also use Mn(2+) ion.

1112:A9D12 RS13055
gene id: 1112:A9D12_RS13055
uniprot id: A0A192D776
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1112:A9D12 RS12440
gene id: 1112:A9D12_RS12440
uniprot id: A0A192D768
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1112:A9D12 RS00970
gene id: 1112:A9D12_RS00970
uniprot id: A0A192D1C1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1112:A9D12 RS05925
gene id: 1112:A9D12_RS05925
uniprot id: A0A192D250
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02300
gene id: 1112:A9D12_RS02300
uniprot id: A0A192D2H3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1112:A9D12 RS02480
gene id: 1112:A9D12_RS02480
uniprot id: A0A192D1I3
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS08755
gene id: 1112:A9D12_RS08755
uniprot id: A0A192D5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1112:A9D12 RS13325
gene id: 1112:A9D12_RS13325
uniprot id: A0A192D7M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS06940
gene id: 1112:A9D12_RS06940
uniprot id: A0A192D2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1112:A9D12 RS06575
gene id: 1112:A9D12_RS06575
uniprot id: A0A192D7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1112:A9D12 RS14140
gene id: 1112:A9D12_RS14140
uniprot id: A0A192D7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS11745
gene id: 1112:A9D12_RS11745
uniprot id: A0A192D4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1112:A9D12 RS13915
gene id: 1112:A9D12_RS13915
uniprot id: A0A192D767
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1112:A9D12 RS02560
gene id: 1112:A9D12_RS02560
uniprot id: A0A192D1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1112:A9D12 RS00985
gene id: 1112:A9D12_RS00985
uniprot id: A0A192D0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1112:A9D12 RS03430
gene id: 1112:A9D12_RS03430
uniprot id: A0A192D1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS02550
gene id: 1112:A9D12_RS02550
uniprot id: A0A192D2K7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1112:A9D12 RS06005
gene id: 1112:A9D12_RS06005
uniprot id: A0A192D478
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1112:A9D12 RS12150
gene id: 1112:A9D12_RS12150
uniprot id: A0A192D639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1112:A9D12 RS04040
gene id: 1112:A9D12_RS04040
uniprot id: A0A192D3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1112:A9D12 RS12380
gene id: 1112:A9D12_RS12380
uniprot id: A0A192D6E9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1112:A9D12 RS13070
gene id: 1112:A9D12_RS13070
uniprot id: A0A192D7H7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS10620
gene id: 1112:A9D12_RS10620
uniprot id: A0A192D4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1112:A9D12 RS06000
gene id: 1112:A9D12_RS06000
uniprot id: A0A192D259
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1112:A9D12 RS02715
gene id: 1112:A9D12_RS02715
uniprot id: A0A192D212
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS01565
gene id: 1112:A9D12_RS01565
uniprot id: A0A192D012
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1112:A9D12 RS06400
gene id: 1112:A9D12_RS06400
uniprot id: A0A192D4E0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1112:A9D12 RS03420
gene id: 1112:A9D12_RS03420
uniprot id: A0A192D0V0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS04485
gene id: 1112:A9D12_RS04485
uniprot id: A0A192D2J5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS14305
gene id: 1112:A9D12_RS14305
uniprot id: A0A192D7D9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1112:A9D12 RS03785
gene id: 1112:A9D12_RS03785
uniprot id: A0A192D2I4
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1112:A9D12 RS09955
gene id: 1112:A9D12_RS09955
uniprot id: A0A192D618
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1112:A9D12 RS00235
gene id: 1112:A9D12_RS00235
uniprot id: A0A192D1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS03230
gene id: 1112:A9D12_RS03230
uniprot id: A0A192D2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1112:A9D12 RS12190
gene id: 1112:A9D12_RS12190
uniprot id: A0A192D763
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1112:A9D12 RS09095
gene id: 1112:A9D12_RS09095
uniprot id: A0A192D3L2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1112:A9D12 RS07150
gene id: 1112:A9D12_RS07150
uniprot id: A0A192D4D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1112:A9D12 RS02770
gene id: 1112:A9D12_RS02770
uniprot id: A0A192D220
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1112:A9D12 RS10630
gene id: 1112:A9D12_RS10630
uniprot id: A0A192D5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1112:A9D12 RS07230
gene id: 1112:A9D12_RS07230
uniprot id: A0A192D4R1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1112:A9D12 RS13970
gene id: 1112:A9D12_RS13970
uniprot id: A0A192D7P3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08575
gene id: 1112:A9D12_RS08575
uniprot id: A0A192D4G4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS00580
gene id: 1112:A9D12_RS00580
uniprot id: A0A192D157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1112:A9D12 RS00745
gene id: 1112:A9D12_RS00745
uniprot id: A0A192D184
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS04125
gene id: 1112:A9D12_RS04125
uniprot id: A0A192D2C9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1112:A9D12 RS01755
gene id: 1112:A9D12_RS01755
uniprot id: A0A192D046
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08185
gene id: 1112:A9D12_RS08185
uniprot id: A0A192D4V8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1112:A9D12 RS03750
gene id: 1112:A9D12_RS03750
uniprot id: A0A192D363
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1112:A9D12 RS13695
gene id: 1112:A9D12_RS13695
uniprot id: A0A192D7T9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1112:A9D12 RS11895
gene id: 1112:A9D12_RS11895
uniprot id: A0A192D4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1112:A9D12 RS00400
gene id: 1112:A9D12_RS00400
uniprot id: A0A192D127
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1112:A9D12 RS06480
gene id: 1112:A9D12_RS06480
uniprot id: A0A192D3G9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1112:A9D12 RS03415
gene id: 1112:A9D12_RS03415
uniprot id: A0A192D2H7
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS11505
gene id: 1112:A9D12_RS11505
uniprot id: A0A192D6G8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1112:A9D12 RS09780
gene id: 1112:A9D12_RS09780
uniprot id: A0A192D5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1112:A9D12 RS12870
gene id: 1112:A9D12_RS12870
uniprot id: A0A192D742
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08910
gene id: 1112:A9D12_RS08910
uniprot id: A0A192D4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1112:A9D12 RS00880
gene id: 1112:A9D12_RS00880
uniprot id: A0A192CZR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1112:A9D12 RS11475
gene id: 1112:A9D12_RS11475
uniprot id: A0A192D4N5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1112:A9D12 RS07905
gene id: 1112:A9D12_RS07905
uniprot id: A0A192D4R4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1112:A9D12 RS09365
gene id: 1112:A9D12_RS09365
uniprot id: A0A192D3R7
names: Similarity
messages: Belongs to the peptidase C56 family.

1112:A9D12 RS00345
gene id: 1112:A9D12_RS00345
uniprot id: A0A192D124
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1112:A9D12 RS09375
gene id: 1112:A9D12_RS09375
uniprot id: A0A192D6X1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1112:A9D12 RS02610
gene id: 1112:A9D12_RS02610
uniprot id: A0A192D1K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1112:A9D12 RS06485
gene id: 1112:A9D12_RS06485
uniprot id: A0A192D3R3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS08415
gene id: 1112:A9D12_RS08415
uniprot id: A0A192D6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1112:A9D12 RS12640
gene id: 1112:A9D12_RS12640
uniprot id: A0A192D578
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1112:A9D12 RS05470
gene id: 1112:A9D12_RS05470
uniprot id: A0A192D3I1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1112:A9D12 RS07370
gene id: 1112:A9D12_RS07370
uniprot id: A0A192D4T6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1112:A9D12 RS10130
gene id: 1112:A9D12_RS10130
uniprot id: A0A192D644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1112:A9D12 RS12635
gene id: 1112:A9D12_RS12635
uniprot id: A0A192D702
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS09690
gene id: 1112:A9D12_RS09690
uniprot id: A0A192D559
names: Similarity
messages: Belongs to the BolA/IbaG family.

1112:A9D12 RS04830
gene id: 1112:A9D12_RS04830
uniprot id: A0A192D1J9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1112:A9D12 RS08395
gene id: 1112:A9D12_RS08395
uniprot id: A0A192D4B5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS09040
gene id: 1112:A9D12_RS09040
uniprot id: A0A192D4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1112:A9D12 RS00525
gene id: 1112:A9D12_RS00525
uniprot id: A0A192D1R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1112:A9D12 RS02245
gene id: 1112:A9D12_RS02245
uniprot id: A0A192D1Y0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1112:A9D12 RS00790
gene id: 1112:A9D12_RS00790
uniprot id: A0A192D196
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1112:A9D12 RS13005
gene id: 1112:A9D12_RS13005
uniprot id: A0A192D766
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1112:A9D12 RS08520
gene id: 1112:A9D12_RS08520
uniprot id: A0A192D4F3
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02410
gene id: 1112:A9D12_RS02410
uniprot id: A0A192D2I8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1112:A9D12 RS07130
gene id: 1112:A9D12_RS07130
uniprot id: A0A192D4P6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1112:A9D12 RS01360
gene id: 1112:A9D12_RS01360
uniprot id: A0A192D1I4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1112:A9D12 RS10160
gene id: 1112:A9D12_RS10160
uniprot id: A0A192D650
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1112:A9D12 RS03150
gene id: 1112:A9D12_RS03150
uniprot id: A0A192D0R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1112:A9D12 RS00360
gene id: 1112:A9D12_RS00360
uniprot id: A0A192D1N8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1112:A9D12 RS10840
gene id: 1112:A9D12_RS10840
uniprot id: A0A192D5R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1112:A9D12 RS09890
gene id: 1112:A9D12_RS09890
uniprot id: A0A192D5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1112:A9D12 RS12485
gene id: 1112:A9D12_RS12485
uniprot id: A0A192D6X6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS07530
gene id: 1112:A9D12_RS07530
uniprot id: A0A192D3Y3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1112:A9D12 RS11650
gene id: 1112:A9D12_RS11650
uniprot id: A0A192D5V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1112:A9D12 RS03625
gene id: 1112:A9D12_RS03625
uniprot id: A0A192D2F6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS01245
gene id: 1112:A9D12_RS01245
uniprot id: A0A192CZW0
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

1112:A9D12 RS12050
gene id: 1112:A9D12_RS12050
uniprot id: A0A192D6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS13365
gene id: 1112:A9D12_RS13365
uniprot id: A0A192D6X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1112:A9D12 RS01120
gene id: 1112:A9D12_RS01120
uniprot id: A0A192D0U9
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1112:A9D12 RS02975
gene id: 1112:A9D12_RS02975
uniprot id: A0A192D299
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1112:A9D12 RS11540
gene id: 1112:A9D12_RS11540
uniprot id: A0A192D4P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1112:A9D12 RS01230
gene id: 1112:A9D12_RS01230
uniprot id: A0A192D1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1112:A9D12 RS09805
gene id: 1112:A9D12_RS09805
uniprot id: A0A192D597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1112:A9D12 RS08420
gene id: 1112:A9D12_RS08420
uniprot id: A0A192D399
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1112:A9D12 RS02760
gene id: 1112:A9D12_RS02760
uniprot id: A0A192D2P2
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1112:A9D12 RS03165
gene id: 1112:A9D12_RS03165
uniprot id: A0A192D286
names: Function
messages: Multidrug efflux pump.

1112:A9D12 RS11815
gene id: 1112:A9D12_RS11815
uniprot id: A0A192D6L6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1112:A9D12 RS03955
gene id: 1112:A9D12_RS03955
uniprot id: A0A192D3A0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1112:A9D12 RS13870
gene id: 1112:A9D12_RS13870
uniprot id: A0A192D7M3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1112:A9D12 RS12495
gene id: 1112:A9D12_RS12495
uniprot id: A0A192D775
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1112:A9D12 RS11755
gene id: 1112:A9D12_RS11755
uniprot id: A0A192D5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS07595
gene id: 1112:A9D12_RS07595
uniprot id: A0A192D484
names: Similarity
messages: Belongs to the NAPRTase family.

1112:A9D12 RS01870
gene id: 1112:A9D12_RS01870
uniprot id: A0A192D1S5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1112:A9D12 RS10895
gene id: 1112:A9D12_RS10895
uniprot id: A0A192D6G5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS05145
gene id: 1112:A9D12_RS05145
uniprot id: A0A192D2V2
names: Similarity
messages: Belongs to the GARS family.

1112:A9D12 RS07880
gene id: 1112:A9D12_RS07880
uniprot id: A0A192D316
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1112:A9D12 RS07035
gene id: 1112:A9D12_RS07035
uniprot id: A0A192D4N2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1112:A9D12 RS01820
gene id: 1112:A9D12_RS01820
uniprot id: A0A192D056
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1112:A9D12 RS13440
gene id: 1112:A9D12_RS13440
uniprot id: A0A192D6Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1112:A9D12 RS13875
gene id: 1112:A9D12_RS13875
uniprot id: A0A192D5T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1112:A9D12 RS14315
gene id: 1112:A9D12_RS14315
uniprot id: A0A192D609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS05010
gene id: 1112:A9D12_RS05010
uniprot id: A0A192D1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1112:A9D12 RS04880
gene id: 1112:A9D12_RS04880
uniprot id: A0A192D7L0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1112:A9D12 RS10915
gene id: 1112:A9D12_RS10915
uniprot id: A0A192D4G0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1112:A9D12 RS10465
gene id: 1112:A9D12_RS10465
uniprot id: A0A192D485
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1112:A9D12 RS12265
gene id: 1112:A9D12_RS12265
uniprot id: A0A192D658
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1112:A9D12 RS07400
gene id: 1112:A9D12_RS07400
uniprot id: A0A192D2T8
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS11680
gene id: 1112:A9D12_RS11680
uniprot id: A0A192D637
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1112:A9D12 RS04200
gene id: 1112:A9D12_RS04200
uniprot id: A0A192D3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1112:A9D12 RS13405
gene id: 1112:A9D12_RS13405
uniprot id: A0A192D6P4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1112:A9D12 RS04160
gene id: 1112:A9D12_RS04160
uniprot id: A0A192D2W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1112:A9D12 RS10640
gene id: 1112:A9D12_RS10640
uniprot id: A0A192D8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS11830
gene id: 1112:A9D12_RS11830
uniprot id: A0A192D5Y5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS05110
gene id: 1112:A9D12_RS05110
uniprot id: A0A192D358
names: Similarity
messages: Belongs to the HesB/IscA family.

1112:A9D12 RS04525
gene id: 1112:A9D12_RS04525
uniprot id: A0A192D326
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS09900
gene id: 1112:A9D12_RS09900
uniprot id: A0A192D922
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1112:A9D12 RS00460
gene id: 1112:A9D12_RS00460
uniprot id: A0A192D872
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1112:A9D12 RS09555
gene id: 1112:A9D12_RS09555
uniprot id: A0A192D4Z3
names: Similarity
messages: Belongs to the peptidase M16 family.

1112:A9D12 RS09940
gene id: 1112:A9D12_RS09940
uniprot id: A0A192D5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1112:A9D12 RS11400
gene id: 1112:A9D12_RS11400
uniprot id: A0A192D6P1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1112:A9D12 RS11885
gene id: 1112:A9D12_RS11885
uniprot id: A0A192D6M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1112:A9D12 RS06500
gene id: 1112:A9D12_RS06500
uniprot id: A0A192D2E2
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1112:A9D12 RS09025
gene id: 1112:A9D12_RS09025
uniprot id: A0A192D594
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1112:A9D12 RS02265
gene id: 1112:A9D12_RS02265
uniprot id: A0A192D7D7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1112:A9D12 RS10170
gene id: 1112:A9D12_RS10170
uniprot id: A0A192D5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1112:A9D12 RS11385
gene id: 1112:A9D12_RS11385
uniprot id: A0A192D6E6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1112:A9D12 RS10685
gene id: 1112:A9D12_RS10685
uniprot id: A0A192D5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1112:A9D12 RS07095
gene id: 1112:A9D12_RS07095
uniprot id: A0A192D4P1
names: Subcellular Location Annotation
messages: Cytoplasm

1112:A9D12 RS10535
gene id: 1112:A9D12_RS10535
uniprot id: A0A192D6A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1112:A9D12 RS07260
gene id: 1112:A9D12_RS07260
uniprot id: A0A192D3T7
names: Subcellular Location Annotation
messages: chloroplast

1112:A9D12 RS10010
gene id: 1112:A9D12_RS10010
uniprot id: A0A192D566
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1112:A9D12 RS12475
gene id: 1112:A9D12_RS12475
uniprot id: A0A192D683
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1112:A9D12 RS13305
gene id: 1112:A9D12_RS13305
uniprot id: A0A192D6W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1112:A9D12 RS00835
gene id: 1112:A9D12_RS00835
uniprot id: A0A192D0Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1112:A9D12 RS04540
gene id: 1112:A9D12_RS04540
uniprot id: A0A192D2K4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08410
gene id: 1112:A9D12_RS08410
uniprot id: A0A192D4Z2
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1112:A9D12 RS08025
gene id: 1112:A9D12_RS08025
uniprot id: A0A192D4E9
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02175
gene id: 1112:A9D12_RS02175
uniprot id: A0A192D1U4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS09810
gene id: 1112:A9D12_RS09810
uniprot id: A0A192D5N9
names: Similarity
messages: Belongs to the threonine synthase family.

1112:A9D12 RS10320
gene id: 1112:A9D12_RS10320
uniprot id: A0A192D5B3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1112:A9D12 RS05820
gene id: 1112:A9D12_RS05820
uniprot id: A0A192D3G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1112:A9D12 RS12630
gene id: 1112:A9D12_RS12630
uniprot id: A0A192D8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS10540
gene id: 1112:A9D12_RS10540
uniprot id: A0A192D5E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1112:A9D12 RS12935
gene id: 1112:A9D12_RS12935
uniprot id: A0A192D6G2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1112:A9D12 RS10445
gene id: 1112:A9D12_RS10445
uniprot id: A0A192D5D3
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1112:A9D12 RS04195
gene id: 1112:A9D12_RS04195
uniprot id: A0A192D188
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1112:A9D12 RS11825
gene id: 1112:A9D12_RS11825
uniprot id: A0A192D6V8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1112:A9D12 RS05280
gene id: 1112:A9D12_RS05280
uniprot id: A0A192D381
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS03495
gene id: 1112:A9D12_RS03495
uniprot id: A0A192D2J1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS08360
gene id: 1112:A9D12_RS08360
uniprot id: A0A192D4B0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS05425
gene id: 1112:A9D12_RS05425
uniprot id: A0A192D3Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1112:A9D12 RS01990
gene id: 1112:A9D12_RS01990
uniprot id: A0A192D2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS06660
gene id: 1112:A9D12_RS06660
uniprot id: A0A192D3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1112:A9D12 RS04910
gene id: 1112:A9D12_RS04910
uniprot id: A0A192D3Q5
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

1112:A9D12 RS02125
gene id: 1112:A9D12_RS02125
uniprot id: A0A192D1W5
names: Similarity
messages: Belongs to the ArsC family.

1112:A9D12 RS05270
gene id: 1112:A9D12_RS05270
uniprot id: A0A192D3W3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1112:A9D12 RS13220
gene id: 1112:A9D12_RS13220
uniprot id: A0A192D7K2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1112:A9D12 RS08900
gene id: 1112:A9D12_RS08900
uniprot id: A0A192D3I4
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS11470
gene id: 1112:A9D12_RS11470
uniprot id: A0A192D6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1112:A9D12 RS07715
gene id: 1112:A9D12_RS07715
uniprot id: A0A192D4A4
names: Similarity
messages: Belongs to the Gfa family.

1112:A9D12 RS08390
gene id: 1112:A9D12_RS08390
uniprot id: A0A192D596
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1112:A9D12 RS00870
gene id: 1112:A9D12_RS00870
uniprot id: A0A192D1A3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1112:A9D12 RS13790
gene id: 1112:A9D12_RS13790
uniprot id: A0A192D7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1112:A9D12 RS06065
gene id: 1112:A9D12_RS06065
uniprot id: A0A192D3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1112:A9D12 RS10370
gene id: 1112:A9D12_RS10370
uniprot id: A0A192D5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1112:A9D12 RS00485
gene id: 1112:A9D12_RS00485
uniprot id: A0A192D142
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1112:A9D12 RS10825
gene id: 1112:A9D12_RS10825
uniprot id: A0A192D6F5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1112:A9D12 RS12135
gene id: 1112:A9D12_RS12135
uniprot id: A0A192D6R9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1112:A9D12 RS08760
gene id: 1112:A9D12_RS08760
uniprot id: A0A192D4L6
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1112:A9D12 RS06135
gene id: 1112:A9D12_RS06135
uniprot id: A0A192D3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1112:A9D12 RS11920
gene id: 1112:A9D12_RS11920
uniprot id: A0A192D6M8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1112:A9D12 RS07155
gene id: 1112:A9D12_RS07155
uniprot id: A0A192D2P8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1112:A9D12 RS01840
gene id: 1112:A9D12_RS01840
uniprot id: A0A192D1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1112:A9D12 RS10980
gene id: 1112:A9D12_RS10980
uniprot id: A0A192D4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1112:A9D12 RS12130
gene id: 1112:A9D12_RS12130
uniprot id: A0A192D6A2
names: Similarity
messages: Belongs to the UPF0102 family.

1112:A9D12 RS12530
gene id: 1112:A9D12_RS12530
uniprot id: A0A192D780
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1112:A9D12 RS01410
gene id: 1112:A9D12_RS01410
uniprot id: A0A192D1J3
names: Function
names: Similarity
messages: Belongs to the AcsF family.
messages: Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).

1112:A9D12 RS02680
gene id: 1112:A9D12_RS02680
uniprot id: A0A192D7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1112:A9D12 RS04435
gene id: 1112:A9D12_RS04435
uniprot id: A0A192D2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1112:A9D12 RS11575
gene id: 1112:A9D12_RS11575
uniprot id: A0A192D4Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1112:A9D12 RS12365
gene id: 1112:A9D12_RS12365
uniprot id: A0A192D534
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS03205
gene id: 1112:A9D12_RS03205
uniprot id: A0A192D2X6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1112:A9D12 RS11985
gene id: 1112:A9D12_RS11985
uniprot id: A0A192D610
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1112:A9D12 RS08325
gene id: 1112:A9D12_RS08325
uniprot id: A0A192D385
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1112:A9D12 RS02970
gene id: 1112:A9D12_RS02970
uniprot id: A0A192D251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1112:A9D12 RS11620
gene id: 1112:A9D12_RS11620
uniprot id: A0A192D744
names: Similarity
messages: Belongs to the RecJ family.

1112:A9D12 RS03720
gene id: 1112:A9D12_RS03720
uniprot id: A0A192D357
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS01665
gene id: 1112:A9D12_RS01665
uniprot id: A0A192D1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS13020
gene id: 1112:A9D12_RS13020
uniprot id: A0A192D6H7
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS14030
gene id: 1112:A9D12_RS14030
uniprot id: A0A192D5W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1112:A9D12 RS02690
gene id: 1112:A9D12_RS02690
uniprot id: A0A192D209
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1112:A9D12 RS00480
gene id: 1112:A9D12_RS00480
uniprot id: A0A192D0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1112:A9D12 RS12170
gene id: 1112:A9D12_RS12170
uniprot id: A0A192D720
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1112:A9D12 RS03825
gene id: 1112:A9D12_RS03825
uniprot id: A0A192D880
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1112:A9D12 RS05855
gene id: 1112:A9D12_RS05855
uniprot id: A0A192D3R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1112:A9D12 RS09115
gene id: 1112:A9D12_RS09115
uniprot id: A0A192D4X1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1112:A9D12 RS12825
gene id: 1112:A9D12_RS12825
uniprot id: A0A192D6E1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1112:A9D12 RS01625
gene id: 1112:A9D12_RS01625
uniprot id: A0A192D023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1112:A9D12 RS13370
gene id: 1112:A9D12_RS13370
uniprot id: A0A192D931
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1112:A9D12 RS12060
gene id: 1112:A9D12_RS12060
uniprot id: A0A192D6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1112:A9D12 RS13900
gene id: 1112:A9D12_RS13900
uniprot id: A0A192D5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1112:A9D12 RS06795
gene id: 1112:A9D12_RS06795
uniprot id: A0A192D4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1112:A9D12 RS13855
gene id: 1112:A9D12_RS13855
uniprot id: A0A192D7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS08935
gene id: 1112:A9D12_RS08935
uniprot id: A0A192D884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1112:A9D12 RS03610
gene id: 1112:A9D12_RS03610
uniprot id: A0A192D0Y6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS08825
gene id: 1112:A9D12_RS08825
uniprot id: A0A192D6V0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS13610
gene id: 1112:A9D12_RS13610
uniprot id: A0A192D7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS13395
gene id: 1112:A9D12_RS13395
uniprot id: A0A192D8D4
names: Similarity
messages: Belongs to the UPF0758 family.

1112:A9D12 RS08995
gene id: 1112:A9D12_RS08995
uniprot id: A0A192D4V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1112:A9D12 RS02415
gene id: 1112:A9D12_RS02415
uniprot id: A0A192D1H3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS06720
gene id: 1112:A9D12_RS06720
uniprot id: A0A192D3U6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1112:A9D12 RS12520
gene id: 1112:A9D12_RS12520
uniprot id: A0A192D6Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS12655
gene id: 1112:A9D12_RS12655
uniprot id: A0A192D6J4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1112:A9D12 RS08385
gene id: 1112:A9D12_RS08385
uniprot id: A0A192D394
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1112:A9D12 RS10340
gene id: 1112:A9D12_RS10340
uniprot id: A0A192D467
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1112:A9D12 RS09785
gene id: 1112:A9D12_RS09785
uniprot id: A0A192D8B3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1112:A9D12 RS09605
gene id: 1112:A9D12_RS09605
uniprot id: A0A192D5I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1112:A9D12 RS03455
gene id: 1112:A9D12_RS03455
uniprot id: A0A192D309
names: Similarity
messages: Belongs to the peptidase M1 family.

1112:A9D12 RS10675
gene id: 1112:A9D12_RS10675
uniprot id: A0A192D4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1112:A9D12 RS13945
gene id: 1112:A9D12_RS13945
uniprot id: A0A192D7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1112:A9D12 RS08365
gene id: 1112:A9D12_RS08365
uniprot id: A0A192D7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS07815
gene id: 1112:A9D12_RS07815
uniprot id: A0A192D4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1112:A9D12 RS10935
gene id: 1112:A9D12_RS10935
uniprot id: A0A192D685
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1112:A9D12 RS09545
gene id: 1112:A9D12_RS09545
uniprot id: A0A192D3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1112:A9D12 RS03965
gene id: 1112:A9D12_RS03965
uniprot id: A0A192D297
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS12225
gene id: 1112:A9D12_RS12225
uniprot id: A0A192D510
names: Similarity
messages: Belongs to the alanine racemase family.

1112:A9D12 RS02785
gene id: 1112:A9D12_RS02785
uniprot id: A0A192D6C5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1112:A9D12 RS06855
gene id: 1112:A9D12_RS06855
uniprot id: A0A192D816
names: Similarity
messages: Belongs to the histone deacetylase family.

1112:A9D12 RS04415
gene id: 1112:A9D12_RS04415
uniprot id: A0A192D300
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1112:A9D12 RS05675
gene id: 1112:A9D12_RS05675
uniprot id: A0A192D339
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1112:A9D12 RS06160
gene id: 1112:A9D12_RS06160
uniprot id: A0A192D3W6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1112:A9D12 RS06295
gene id: 1112:A9D12_RS06295
uniprot id: A0A192D3N3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1112:A9D12 RS07100
gene id: 1112:A9D12_RS07100
uniprot id: A0A192D3Q9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1112:A9D12 RS03640
gene id: 1112:A9D12_RS03640
uniprot id: A0A192D342
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1112:A9D12 RS07940
gene id: 1112:A9D12_RS07940
uniprot id: A0A192D325
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1112:A9D12 RS10830
gene id: 1112:A9D12_RS10830
uniprot id: A0A192D951
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1112:A9D12 RS09735
gene id: 1112:A9D12_RS09735
uniprot id: A0A192D5Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1112:A9D12 RS00715
gene id: 1112:A9D12_RS00715
uniprot id: A0A192D0N9
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02730
gene id: 1112:A9D12_RS02730
uniprot id: A0A192D0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1112:A9D12 RS11780
gene id: 1112:A9D12_RS11780
uniprot id: A0A192D5X7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1112:A9D12 RS13285
gene id: 1112:A9D12_RS13285
uniprot id: A0A192D7B6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1112:A9D12 RS08295
gene id: 1112:A9D12_RS08295
uniprot id: A0A192D380
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

1112:A9D12 RS03895
gene id: 1112:A9D12_RS03895
uniprot id: A0A192D7I5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1112:A9D12 RS13720
gene id: 1112:A9D12_RS13720
uniprot id: A0A192D7U4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1112:A9D12 RS09655
gene id: 1112:A9D12_RS09655
uniprot id: A0A192D508
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1112:A9D12 RS04230
gene id: 1112:A9D12_RS04230
uniprot id: A0A192D2E8
names: Similarity
messages: Belongs to the PhzF family.

1112:A9D12 RS06120
gene id: 1112:A9D12_RS06120
uniprot id: A0A192D498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1112:A9D12 RS12650
gene id: 1112:A9D12_RS12650
uniprot id: A0A192D6B2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1112:A9D12 RS10595
gene id: 1112:A9D12_RS10595
uniprot id: A0A192D6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1112:A9D12 RS01275
gene id: 1112:A9D12_RS01275
uniprot id: A0A192CZW5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1112:A9D12 RS14070
gene id: 1112:A9D12_RS14070
uniprot id: A0A192D718
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1112:A9D12 RS00650
gene id: 1112:A9D12_RS00650
uniprot id: A0A192D0M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1112:A9D12 RS09020
gene id: 1112:A9D12_RS09020
uniprot id: A0A192D4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1112:A9D12 RS00615
gene id: 1112:A9D12_RS00615
uniprot id: A0A192CZL8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

1112:A9D12 RS08955
gene id: 1112:A9D12_RS08955
uniprot id: A0A192D4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1112:A9D12 RS03255
gene id: 1112:A9D12_RS03255
uniprot id: A0A192D866
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1112:A9D12 RS05330
gene id: 1112:A9D12_RS05330
uniprot id: A0A192D2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1112:A9D12 RS14295
gene id: 1112:A9D12_RS14295
uniprot id: A0A192D848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1112:A9D12 RS13360
gene id: 1112:A9D12_RS13360
uniprot id: A0A192D6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1112:A9D12 RS07640
gene id: 1112:A9D12_RS07640
uniprot id: A0A192D6R3
names: Similarity
messages: Belongs to the lycopene cyclase family.

1112:A9D12 RS03950
gene id: 1112:A9D12_RS03950
uniprot id: A0A192D149
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1112:A9D12 RS00260
gene id: 1112:A9D12_RS00260
uniprot id: A0A192CZF8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS03175
gene id: 1112:A9D12_RS03175
uniprot id: A0A192D0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1112:A9D12 RS08200
gene id: 1112:A9D12_RS08200
uniprot id: A0A192D6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1112:A9D12 RS13170
gene id: 1112:A9D12_RS13170
uniprot id: A0A192D6T5
names: Similarity
messages: Belongs to the peptidase S66 family.

1112:A9D12 RS10510
gene id: 1112:A9D12_RS10510
uniprot id: A0A192D695
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1112:A9D12 RS10820
gene id: 1112:A9D12_RS10820
uniprot id: A0A192D4E6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1112:A9D12 RS08835
gene id: 1112:A9D12_RS08835
uniprot id: A0A192D4S7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1112:A9D12 RS08495
gene id: 1112:A9D12_RS08495
uniprot id: A0A192D876
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1112:A9D12 RS01885
gene id: 1112:A9D12_RS01885
uniprot id: A0A192D2B9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1112:A9D12 RS12395
gene id: 1112:A9D12_RS12395
uniprot id: A0A192D540
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1112:A9D12 RS08790
gene id: 1112:A9D12_RS08790
uniprot id: A0A192D4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1112:A9D12 RS01185
gene id: 1112:A9D12_RS01185
uniprot id: A0A192D1F4
names: Similarity
messages: Belongs to the virb1 family.

1112:A9D12 RS14340
gene id: 1112:A9D12_RS14340
uniprot id: A0A192D614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS02255
gene id: 1112:A9D12_RS02255
uniprot id: A0A192D0C1
names: Similarity
messages: Belongs to the UPF0174 family.

1112:A9D12 RS07545
gene id: 1112:A9D12_RS07545
uniprot id: A0A192D4K1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1112:A9D12 RS10020
gene id: 1112:A9D12_RS10020
uniprot id: A0A192D5R7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS04700
gene id: 1112:A9D12_RS04700
uniprot id: A0A192D2M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08570
gene id: 1112:A9D12_RS08570
uniprot id: A0A192D5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS09560
gene id: 1112:A9D12_RS09560
uniprot id: A0A192D541
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1112:A9D12 RS06025
gene id: 1112:A9D12_RS06025
uniprot id: A0A192D264
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1112:A9D12 RS04515
gene id: 1112:A9D12_RS04515
uniprot id: A0A192D2J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS02980
gene id: 1112:A9D12_RS02980
uniprot id: A0A192D0N3
names: Similarity
messages: Belongs to the ArsC family.

1112:A9D12 RS07840
gene id: 1112:A9D12_RS07840
uniprot id: A0A192D4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1112:A9D12 RS09790
gene id: 1112:A9D12_RS09790
uniprot id: A0A192D3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1112:A9D12 RS04235
gene id: 1112:A9D12_RS04235
uniprot id: A0A192D2R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1112:A9D12 RS07660
gene id: 1112:A9D12_RS07660
uniprot id: A0A192D494
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1112:A9D12 RS09485
gene id: 1112:A9D12_RS09485
uniprot id: A0A192D3T5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1112:A9D12 RS04670
gene id: 1112:A9D12_RS04670
uniprot id: A0A192D2M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1112:A9D12 RS10525
gene id: 1112:A9D12_RS10525
uniprot id: A0A192D5Z4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS11600
gene id: 1112:A9D12_RS11600
uniprot id: A0A192D6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS10890
gene id: 1112:A9D12_RS10890
uniprot id: A0A192D4F5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1112:A9D12 RS14360
gene id: 1112:A9D12_RS14360
uniprot id: A0A192D7F0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1112:A9D12 RS13445
gene id: 1112:A9D12_RS13445
uniprot id: A0A192D7E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1112:A9D12 RS05995
gene id: 1112:A9D12_RS05995
uniprot id: A0A192D3T3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1112:A9D12 RS03250
gene id: 1112:A9D12_RS03250
uniprot id: A0A192D7Q6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1112:A9D12 RS11835
gene id: 1112:A9D12_RS11835
uniprot id: A0A192D660
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1112:A9D12 RS07830
gene id: 1112:A9D12_RS07830
uniprot id: A0A192D434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1112:A9D12 RS06050
gene id: 1112:A9D12_RS06050
uniprot id: A0A192D3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1112:A9D12 RS03445
gene id: 1112:A9D12_RS03445
uniprot id: A0A192D0V5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1112:A9D12 RS06625
gene id: 1112:A9D12_RS06625
uniprot id: A0A192D2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS03440
gene id: 1112:A9D12_RS03440
uniprot id: A0A192D2I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1112:A9D12 RS09145
gene id: 1112:A9D12_RS09145
uniprot id: A0A192D4S9
names: Similarity
messages: Belongs to the YkuD family.

1112:A9D12 RS04275
gene id: 1112:A9D12_RS04275
uniprot id: A0A192D3G2
names: Similarity
messages: Belongs to the peptidase S41A family.

1112:A9D12 RS00490
gene id: 1112:A9D12_RS00490
uniprot id: A0A192D150
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1112:A9D12 RS11255
gene id: 1112:A9D12_RS11255
uniprot id: A0A192D869
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1112:A9D12 RS00965
gene id: 1112:A9D12_RS00965
uniprot id: A0A192D1B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1112:A9D12 RS02465
gene id: 1112:A9D12_RS02465
uniprot id: A0A192D214
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1112:A9D12 RS03850
gene id: 1112:A9D12_RS03850
uniprot id: A0A192D135
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1112:A9D12 RS08350
gene id: 1112:A9D12_RS08350
uniprot id: A0A192D390
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS11675
gene id: 1112:A9D12_RS11675
uniprot id: A0A192D5W2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS05355
gene id: 1112:A9D12_RS05355
uniprot id: A0A192D1U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS10140
gene id: 1112:A9D12_RS10140
uniprot id: A0A192D5E8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1112:A9D12 RS00565
gene id: 1112:A9D12_RS00565
uniprot id: A0A192D7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1112:A9D12 RS04855
gene id: 1112:A9D12_RS04855
uniprot id: A0A192D315
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1112:A9D12 RS07860
gene id: 1112:A9D12_RS07860
uniprot id: A0A192D4C8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1112:A9D12 RS13165
gene id: 1112:A9D12_RS13165
uniprot id: A0A192D6K3
names: Similarity
messages: Belongs to the fabD family.

1112:A9D12 RS13765
gene id: 1112:A9D12_RS13765
uniprot id: A0A192D7K3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1112:A9D12 RS12955
gene id: 1112:A9D12_RS12955
uniprot id: A0A192D783
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1112:A9D12 RS13600
gene id: 1112:A9D12_RS13600
uniprot id: A0A192D7G9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1112:A9D12 RS13675
gene id: 1112:A9D12_RS13675
uniprot id: A0A192D724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1112:A9D12 RS07835
gene id: 1112:A9D12_RS07835
uniprot id: A0A192D4C2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1112:A9D12 RS13105
gene id: 1112:A9D12_RS13105
uniprot id: A0A192D7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1112:A9D12 RS01065
gene id: 1112:A9D12_RS01065
uniprot id: A0A192D1D9
names: Similarity
messages: Belongs to the SufE family.

1112:A9D12 RS11100
gene id: 1112:A9D12_RS11100
uniprot id: A0A192D4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1112:A9D12 RS11445
gene id: 1112:A9D12_RS11445
uniprot id: A0A192D6F6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1112:A9D12 RS00620
gene id: 1112:A9D12_RS00620
uniprot id: A0A192D1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1112:A9D12 RS08310
gene id: 1112:A9D12_RS08310
uniprot id: A0A192D4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1112:A9D12 RS06580
gene id: 1112:A9D12_RS06580
uniprot id: A0A192D3S7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1112:A9D12 RS02120
gene id: 1112:A9D12_RS02120
uniprot id: A0A192D1T5
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12070
gene id: 1112:A9D12_RS12070
uniprot id: A0A192D692
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS11880
gene id: 1112:A9D12_RS11880
uniprot id: A0A192D663
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1112:A9D12 RS13795
gene id: 1112:A9D12_RS13795
uniprot id: A0A192D5S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS05700
gene id: 1112:A9D12_RS05700
uniprot id: A0A192D344
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1112:A9D12 RS10565
gene id: 1112:A9D12_RS10565
uniprot id: A0A192D6A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1112:A9D12 RS12270
gene id: 1112:A9D12_RS12270
uniprot id: A0A192D6C8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1112:A9D12 RS04285
gene id: 1112:A9D12_RS04285
uniprot id: A0A192D8I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1112:A9D12 RS01540
gene id: 1112:A9D12_RS01540
uniprot id: A0A192D006
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1112:A9D12 RS08625
gene id: 1112:A9D12_RS08625
uniprot id: A0A192D4H5
names: Similarity
messages: Belongs to the peptidase A24 family.

1112:A9D12 RS12690
gene id: 1112:A9D12_RS12690
uniprot id: A0A192D712
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS13650
gene id: 1112:A9D12_RS13650
uniprot id: A0A192D7I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1112:A9D12 RS04890
gene id: 1112:A9D12_RS04890
uniprot id: A0A192D7V1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1112:A9D12 RS06845
gene id: 1112:A9D12_RS06845
uniprot id: A0A192D2K0
names: Similarity
messages: Belongs to the YkuD family.

1112:A9D12 RS00120
gene id: 1112:A9D12_RS00120
uniprot id: A0A192D0Y5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS01220
gene id: 1112:A9D12_RS01220
uniprot id: A0A192D216
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS11425
gene id: 1112:A9D12_RS11425
uniprot id: A0A192D4M5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1112:A9D12 RS08725
gene id: 1112:A9D12_RS08725
uniprot id: A0A192D3F5
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS08710
gene id: 1112:A9D12_RS08710
uniprot id: A0A192D4Q8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1112:A9D12 RS10985
gene id: 1112:A9D12_RS10985
uniprot id: A0A192D6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1112:A9D12 RS06095
gene id: 1112:A9D12_RS06095
uniprot id: A0A192D493
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1112:A9D12 RS01630
gene id: 1112:A9D12_RS01630
uniprot id: A0A192D281
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1112:A9D12 RS13940
gene id: 1112:A9D12_RS13940
uniprot id: A0A192D772
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1112:A9D12 RS05580
gene id: 1112:A9D12_RS05580
uniprot id: A0A192D3D0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1112:A9D12 RS03180
gene id: 1112:A9D12_RS03180
uniprot id: A0A192D2X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1112:A9D12 RS11340
gene id: 1112:A9D12_RS11340
uniprot id: A0A192D6E2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1112:A9D12 RS02530
gene id: 1112:A9D12_RS02530
uniprot id: A0A192D224
names: Similarity
messages: Belongs to the CopC family.

1112:A9D12 RS07215
gene id: 1112:A9D12_RS07215
uniprot id: A0A192D420
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1112:A9D12 RS11115
gene id: 1112:A9D12_RS11115
uniprot id: A0A192D5N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS03050
gene id: 1112:A9D12_RS03050
uniprot id: A0A192D1T3
names: Similarity
messages: Belongs to the peptidase A24 family.

1112:A9D12 RS08505
gene id: 1112:A9D12_RS08505
uniprot id: A0A192D507
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1112:A9D12 RS06335
gene id: 1112:A9D12_RS06335
uniprot id: A0A192D2B7
names: Similarity
messages: Belongs to the SDHAF4 family.

1112:A9D12 RS12665
gene id: 1112:A9D12_RS12665
uniprot id: A0A192D582
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS05170
gene id: 1112:A9D12_RS05170
uniprot id: A0A192D2V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1112:A9D12 RS09340
gene id: 1112:A9D12_RS09340
uniprot id: A0A192D4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1112:A9D12 RS10065
gene id: 1112:A9D12_RS10065
uniprot id: A0A192D426
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS03660
gene id: 1112:A9D12_RS03660
uniprot id: A0A192D2M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1112:A9D12 RS12815
gene id: 1112:A9D12_RS12815
uniprot id: A0A192D7D1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS11990
gene id: 1112:A9D12_RS11990
uniprot id: A0A192D676
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1112:A9D12 RS06115
gene id: 1112:A9D12_RS06115
uniprot id: A0A192D279
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1112:A9D12 RS08975
gene id: 1112:A9D12_RS08975
uniprot id: A0A192D585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS02065
gene id: 1112:A9D12_RS02065
uniprot id: A0A192D1V5
names: Similarity
messages: Belongs to the FGGY kinase family.

1112:A9D12 RS12740
gene id: 1112:A9D12_RS12740
uniprot id: A0A192D721
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1112:A9D12 RS04615
gene id: 1112:A9D12_RS04615
uniprot id: A0A192D2X7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1112:A9D12 RS13590
gene id: 1112:A9D12_RS13590
uniprot id: A0A192D6S2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1112:A9D12 RS08370
gene id: 1112:A9D12_RS08370
uniprot id: A0A192D4J9
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

1112:A9D12 RS02910
gene id: 1112:A9D12_RS02910
uniprot id: A0A192D1Q6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS06185
gene id: 1112:A9D12_RS06185
uniprot id: A0A192D3C3
names: Similarity
messages: Belongs to the aldose epimerase family.

1112:A9D12 RS12685
gene id: 1112:A9D12_RS12685
uniprot id: A0A192D6J9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1112:A9D12 RS13210
gene id: 1112:A9D12_RS13210
uniprot id: A0A192D7A0
names: Similarity
messages: Belongs to the GST superfamily.

1112:A9D12 RS03780
gene id: 1112:A9D12_RS03780
uniprot id: A0A192D265
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS00130
gene id: 1112:A9D12_RS00130
uniprot id: A0A192D0Y8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1112:A9D12 RS10805
gene id: 1112:A9D12_RS10805
uniprot id: A0A192D5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1112:A9D12 RS09750
gene id: 1112:A9D12_RS09750
uniprot id: A0A192D569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1112:A9D12 RS01030
gene id: 1112:A9D12_RS01030
uniprot id: A0A192D793
names: Similarity
messages: Belongs to the PspA/IM30 family.

1112:A9D12 RS00975
gene id: 1112:A9D12_RS00975
uniprot id: A0A192CZS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1112:A9D12 RS02665
gene id: 1112:A9D12_RS02665
uniprot id: A0A192D8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS15120
gene id: 1112:A9D12_RS15120
uniprot id: A0A192D261
names: Subcellular Location Annotation
messages: Cytoplasm

1112:A9D12 RS06385
gene id: 1112:A9D12_RS06385
uniprot id: A0A192D3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS00890
gene id: 1112:A9D12_RS00890
uniprot id: A0A192D0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS09355
gene id: 1112:A9D12_RS09355
uniprot id: A0A192D898
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1112:A9D12 RS13860
gene id: 1112:A9D12_RS13860
uniprot id: A0A192D6X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1112:A9D12 RS10135
gene id: 1112:A9D12_RS10135
uniprot id: A0A192D584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1112:A9D12 RS07225
gene id: 1112:A9D12_RS07225
uniprot id: A0A192D2Q8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1112:A9D12 RS10115
gene id: 1112:A9D12_RS10115
uniprot id: A0A192D5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1112:A9D12 RS09950
gene id: 1112:A9D12_RS09950
uniprot id: A0A192D410
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1112:A9D12 RS07335
gene id: 1112:A9D12_RS07335
uniprot id: A0A192D4T1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS07500
gene id: 1112:A9D12_RS07500
uniprot id: A0A192D3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS05420
gene id: 1112:A9D12_RS05420
uniprot id: A0A192D1V7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1112:A9D12 RS01915
gene id: 1112:A9D12_RS01915
uniprot id: A0A192D822
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1112:A9D12 RS01385
gene id: 1112:A9D12_RS01385
uniprot id: A0A192D1I8
names: Similarity
messages: Belongs to the PucC family.

1112:A9D12 RS07265
gene id: 1112:A9D12_RS07265
uniprot id: A0A192D430
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1112:A9D12 RS13890
gene id: 1112:A9D12_RS13890
uniprot id: A0A192D762
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1112:A9D12 RS07580
gene id: 1112:A9D12_RS07580
uniprot id: A0A192D4X5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1112:A9D12 RS10240
gene id: 1112:A9D12_RS10240
uniprot id: A0A192D5A3
names: Similarity
messages: Belongs to the CopC family.

1112:A9D12 RS07325
gene id: 1112:A9D12_RS07325
uniprot id: A0A192D4G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1112:A9D12 RS09170
gene id: 1112:A9D12_RS09170
uniprot id: A0A192D893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1112:A9D12 RS09445
gene id: 1112:A9D12_RS09445
uniprot id: A0A192D5F9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1112:A9D12 RS04720
gene id: 1112:A9D12_RS04720
uniprot id: A0A192D1I0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1112:A9D12 RS08805
gene id: 1112:A9D12_RS08805
uniprot id: A0A192D3H0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS09840
gene id: 1112:A9D12_RS09840
uniprot id: A0A192D5P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1112:A9D12 RS04215
gene id: 1112:A9D12_RS04215
uniprot id: A0A192D2W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS09285
gene id: 1112:A9D12_RS09285
uniprot id: A0A192D4Z6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1112:A9D12 RS08600
gene id: 1112:A9D12_RS08600
uniprot id: A0A192D4H0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS03810
gene id: 1112:A9D12_RS03810
uniprot id: A0A192D2I9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1112:A9D12 RS10530
gene id: 1112:A9D12_RS10530
uniprot id: A0A192D496
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1112:A9D12 RS08785
gene id: 1112:A9D12_RS08785
uniprot id: A0A192D5G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1112:A9D12 RS00445
gene id: 1112:A9D12_RS00445
uniprot id: A0A192D1Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1112:A9D12 RS09865
gene id: 1112:A9D12_RS09865
uniprot id: A0A192D5A7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1112:A9D12 RS01000
gene id: 1112:A9D12_RS01000
uniprot id: A0A192CZS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1112:A9D12 RS13865
gene id: 1112:A9D12_RS13865
uniprot id: A0A192D757
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1112:A9D12 RS08905
gene id: 1112:A9D12_RS08905
uniprot id: A0A192D5I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS07165
gene id: 1112:A9D12_RS07165
uniprot id: A0A192D3S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1112:A9D12 RS05910
gene id: 1112:A9D12_RS05910
uniprot id: A0A192D379
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1112:A9D12 RS08745
gene id: 1112:A9D12_RS08745
uniprot id: A0A192D553
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS05655
gene id: 1112:A9D12_RS05655
uniprot id: A0A192D201
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS04520
gene id: 1112:A9D12_RS04520
uniprot id: A0A192D2W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1112:A9D12 RS07535
gene id: 1112:A9D12_RS07535
uniprot id: A0A192D7U3
names: Similarity
messages: Belongs to the peptidase S45 family.

1112:A9D12 RS07030
gene id: 1112:A9D12_RS07030
uniprot id: A0A192D2N1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1112:A9D12 RS02280
gene id: 1112:A9D12_RS02280
uniprot id: A0A192D1F2
names: Similarity
messages: Belongs to the SCO1/2 family.

1112:A9D12 RS00080
gene id: 1112:A9D12_RS00080
uniprot id: A0A192CZC6
names: Similarity
messages: Belongs to the pirin family.

1112:A9D12 RS01740
gene id: 1112:A9D12_RS01740
uniprot id: A0A192D153
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1112:A9D12 RS08695
gene id: 1112:A9D12_RS08695
uniprot id: A0A192D3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1112:A9D12 RS03925
gene id: 1112:A9D12_RS03925
uniprot id: A0A192D144
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1112:A9D12 RS10695
gene id: 1112:A9D12_RS10695
uniprot id: A0A192D630
names: Similarity
messages: Belongs to the histone deacetylase family.

1112:A9D12 RS06015
gene id: 1112:A9D12_RS06015
uniprot id: A0A192D3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1112:A9D12 RS05865
gene id: 1112:A9D12_RS05865
uniprot id: A0A192D7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS03745
gene id: 1112:A9D12_RS03745
uniprot id: A0A192D111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1112:A9D12 RS12220
gene id: 1112:A9D12_RS12220
uniprot id: A0A192D6T4
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS01300
gene id: 1112:A9D12_RS01300
uniprot id: A0A192D1H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

1112:A9D12 RS06895
gene id: 1112:A9D12_RS06895
uniprot id: A0A192D3X4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1112:A9D12 RS04960
gene id: 1112:A9D12_RS04960
uniprot id: A0A192D3R4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1112:A9D12 RS08715
gene id: 1112:A9D12_RS08715
uniprot id: A0A192D548
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1112:A9D12 RS01420
gene id: 1112:A9D12_RS01420
uniprot id: A0A192D252
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1112:A9D12 RS01015
gene id: 1112:A9D12_RS01015
uniprot id: A0A192D0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1112:A9D12 RS02705
gene id: 1112:A9D12_RS02705
uniprot id: A0A192D2N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1112:A9D12 RS07870
gene id: 1112:A9D12_RS07870
uniprot id: A0A192D4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1112:A9D12 RS00040
gene id: 1112:A9D12_RS00040
uniprot id: A0A192D0C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1112:A9D12 RS00150
gene id: 1112:A9D12_RS00150
uniprot id: A0A192D0E6
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS08275
gene id: 1112:A9D12_RS08275
uniprot id: A0A192D580
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1112:A9D12 RS05310
gene id: 1112:A9D12_RS05310
uniprot id: A0A192D386
names: Similarity
messages: Belongs to the glutamate synthase family.

1112:A9D12 RS13835
gene id: 1112:A9D12_RS13835
uniprot id: A0A192D6X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1112:A9D12 RS03360
gene id: 1112:A9D12_RS03360
uniprot id: A0A192D871
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1112:A9D12 RS07070
gene id: 1112:A9D12_RS07070
uniprot id: A0A192D402
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS00825
gene id: 1112:A9D12_RS00825
uniprot id: A0A192D882
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1112:A9D12 RS01100
gene id: 1112:A9D12_RS01100
uniprot id: A0A192D1D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1112:A9D12 RS06030
gene id: 1112:A9D12_RS06030
uniprot id: A0A192D483
names: Subcellular Location Annotation
messages: Secreted

1112:A9D12 RS02000
gene id: 1112:A9D12_RS02000
uniprot id: A0A192D1R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1112:A9D12 RS12615
gene id: 1112:A9D12_RS12615
uniprot id: A0A192D796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1112:A9D12 RS14010
gene id: 1112:A9D12_RS14010
uniprot id: A0A192D7Z8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1112:A9D12 RS06260
gene id: 1112:A9D12_RS06260
uniprot id: A0A192D6L7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1112:A9D12 RS11430
gene id: 1112:A9D12_RS11430
uniprot id: A0A192D6P6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS00365
gene id: 1112:A9D12_RS00365
uniprot id: A0A192D0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1112:A9D12 RS03470
gene id: 1112:A9D12_RS03470
uniprot id: A0A192D2I6
names: Subunit
messages: Homotetramer.

1112:A9D12 RS05435
gene id: 1112:A9D12_RS05435
uniprot id: A0A192D3A5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS03875
gene id: 1112:A9D12_RS03875
uniprot id: A0A192D2J8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1112:A9D12 RS10435
gene id: 1112:A9D12_RS10435
uniprot id: A0A192D480
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1112:A9D12 RS02395
gene id: 1112:A9D12_RS02395
uniprot id: A0A192D202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS01090
gene id: 1112:A9D12_RS01090
uniprot id: A0A192D892
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1112:A9D12 RS05920
gene id: 1112:A9D12_RS05920
uniprot id: A0A192D3S2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS11370
gene id: 1112:A9D12_RS11370
uniprot id: A0A192D8X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS12895
gene id: 1112:A9D12_RS12895
uniprot id: A0A192D747
names: Similarity
messages: Belongs to the virb1 family.

1112:A9D12 RS00205
gene id: 1112:A9D12_RS00205
uniprot id: A0A192CZE9
names: Similarity
messages: Belongs to the peptidase M16 family.

1112:A9D12 RS01160
gene id: 1112:A9D12_RS01160
uniprot id: A0A192D207
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1112:A9D12 RS08675
gene id: 1112:A9D12_RS08675
uniprot id: A0A192D5E5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1112:A9D12 RS11135
gene id: 1112:A9D12_RS11135
uniprot id: A0A192D864
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1112:A9D12 RS13965
gene id: 1112:A9D12_RS13965
uniprot id: A0A192D777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1112:A9D12 RS10095
gene id: 1112:A9D12_RS10095
uniprot id: A0A192D431
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS07285
gene id: 1112:A9D12_RS07285
uniprot id: A0A192D3U2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1112:A9D12 RS08980
gene id: 1112:A9D12_RS08980
uniprot id: A0A192D3J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1112:A9D12 RS06150
gene id: 1112:A9D12_RS06150
uniprot id: A0A192D3B8
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS05595
gene id: 1112:A9D12_RS05595
uniprot id: A0A192D418
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1112:A9D12 RS08650
gene id: 1112:A9D12_RS08650
uniprot id: A0A192D4I0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1112:A9D12 RS09860
gene id: 1112:A9D12_RS09860
uniprot id: A0A192D547
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1112:A9D12 RS04440
gene id: 1112:A9D12_RS04440
uniprot id: A0A192D306
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS05050
gene id: 1112:A9D12_RS05050
uniprot id: A0A192D2T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1112:A9D12 RS00670
gene id: 1112:A9D12_RS00670
uniprot id: A0A192CZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1112:A9D12 RS09305
gene id: 1112:A9D12_RS09305
uniprot id: A0A192D4V3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS13850
gene id: 1112:A9D12_RS13850
uniprot id: A0A192D5T2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1112:A9D12 RS05150
gene id: 1112:A9D12_RS05150
uniprot id: A0A192D362
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1112:A9D12 RS08595
gene id: 1112:A9D12_RS08595
uniprot id: A0A192D5D0
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS03945
gene id: 1112:A9D12_RS03945
uniprot id: A0A192D2S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS06860
gene id: 1112:A9D12_RS06860
uniprot id: A0A192D3M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1112:A9D12 RS13030
gene id: 1112:A9D12_RS13030
uniprot id: A0A192D771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS08925
gene id: 1112:A9D12_RS08925
uniprot id: A0A192D581
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1112:A9D12 RS09715
gene id: 1112:A9D12_RS09715
uniprot id: A0A192D519
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1112:A9D12 RS05990
gene id: 1112:A9D12_RS05990
uniprot id: A0A192D3J2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1112:A9D12 RS05900
gene id: 1112:A9D12_RS05900
uniprot id: A0A192D245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1112:A9D12 RS08690
gene id: 1112:A9D12_RS08690
uniprot id: A0A192D543
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1112:A9D12 RS01225
gene id: 1112:A9D12_RS01225
uniprot id: A0A192D0W7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1112:A9D12 RS09540
gene id: 1112:A9D12_RS09540
uniprot id: A0A192D5H5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1112:A9D12 RS14120
gene id: 1112:A9D12_RS14120
uniprot id: A0A192D5X8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1112:A9D12 RS04250
gene id: 1112:A9D12_RS04250
uniprot id: A0A192D3F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1112:A9D12 RS11765
gene id: 1112:A9D12_RS11765
uniprot id: A0A192D6K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1112:A9D12 RS02035
gene id: 1112:A9D12_RS02035
uniprot id: A0A192D1V0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1112:A9D12 RS00700
gene id: 1112:A9D12_RS00700
uniprot id: A0A192D181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1112:A9D12 RS02460
gene id: 1112:A9D12_RS02460
uniprot id: A0A192D8E1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1112:A9D12 RS08135
gene id: 1112:A9D12_RS08135
uniprot id: A0A192D356
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1112:A9D12 RS03130
gene id: 1112:A9D12_RS03130
uniprot id: A0A192D2W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS03145
gene id: 1112:A9D12_RS03145
uniprot id: A0A192D2D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1112:A9D12 RS09585
gene id: 1112:A9D12_RS09585
uniprot id: A0A192D5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1112:A9D12 RS14275
gene id: 1112:A9D12_RS14275
uniprot id: A0A192D7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1112:A9D12 RS09620
gene id: 1112:A9D12_RS09620
uniprot id: A0A192D503
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1112:A9D12 RS03840
gene id: 1112:A9D12_RS03840
uniprot id: A0A192D2J3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1112:A9D12 RS02645
gene id: 1112:A9D12_RS02645
uniprot id: A0A192D204
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1112:A9D12 RS06470
gene id: 1112:A9D12_RS06470
uniprot id: A0A192D8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1112:A9D12 RS11730
gene id: 1112:A9D12_RS11730
uniprot id: A0A192D642
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1112:A9D12 RS12525
gene id: 1112:A9D12_RS12525
uniprot id: A0A192D560
names: Similarity
messages: Belongs to the TrpC family.

1112:A9D12 RS11130
gene id: 1112:A9D12_RS11130
uniprot id: A0A192D5V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1112:A9D12 RS10470
gene id: 1112:A9D12_RS10470
uniprot id: A0A192D689
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1112:A9D12 RS13230
gene id: 1112:A9D12_RS13230
uniprot id: A0A192D6U5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1112:A9D12 RS12305
gene id: 1112:A9D12_RS12305
uniprot id: A0A192D6D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS11040
gene id: 1112:A9D12_RS11040
uniprot id: A0A192D4H8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1112:A9D12 RS04905
gene id: 1112:A9D12_RS04905
uniprot id: A0A192D1K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1112:A9D12 RS02755
gene id: 1112:A9D12_RS02755
uniprot id: A0A192D0J3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1112:A9D12 RS11735
gene id: 1112:A9D12_RS11735
uniprot id: A0A192D6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1112:A9D12 RS09665
gene id: 1112:A9D12_RS09665
uniprot id: A0A192D5J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1112:A9D12 RS08890
gene id: 1112:A9D12_RS08890
uniprot id: A0A192D4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS01575
gene id: 1112:A9D12_RS01575
uniprot id: A0A192D125
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1112:A9D12 RS05630
gene id: 1112:A9D12_RS05630
uniprot id: A0A192D423
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS04010
gene id: 1112:A9D12_RS04010
uniprot id: A0A192D158
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1112:A9D12 RS10785
gene id: 1112:A9D12_RS10785
uniprot id: A0A192D4E2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1112:A9D12 RS10780
gene id: 1112:A9D12_RS10780
uniprot id: A0A192D645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1112:A9D12 RS11420
gene id: 1112:A9D12_RS11420
uniprot id: A0A192D6F2
names: Similarity
messages: Belongs to the transketolase family.

1112:A9D12 RS12925
gene id: 1112:A9D12_RS12925
uniprot id: A0A192D5C6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS05370
gene id: 1112:A9D12_RS05370
uniprot id: A0A192D7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS09550
gene id: 1112:A9D12_RS09550
uniprot id: A0A192D5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS13355
gene id: 1112:A9D12_RS13355
uniprot id: A0A192D7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1112:A9D12 RS12540
gene id: 1112:A9D12_RS12540
uniprot id: A0A192D6H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1112:A9D12 RS04915
gene id: 1112:A9D12_RS04915
uniprot id: A0A192D2R4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1112:A9D12 RS00430
gene id: 1112:A9D12_RS00430
uniprot id: A0A192D627
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1112:A9D12 RS12885
gene id: 1112:A9D12_RS12885
uniprot id: A0A192D6F1
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1112:A9D12 RS10680
gene id: 1112:A9D12_RS10680
uniprot id: A0A192D6C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1112:A9D12 RS04130
gene id: 1112:A9D12_RS04130
uniprot id: A0A192D2P5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1112:A9D12 RS01585
gene id: 1112:A9D12_RS01585
uniprot id: A0A192D1M3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1112:A9D12 RS01315
gene id: 1112:A9D12_RS01315
uniprot id: A0A192D0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1112:A9D12 RS02435
gene id: 1112:A9D12_RS02435
uniprot id: A0A192D0E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1112:A9D12 RS02390
gene id: 1112:A9D12_RS02390
uniprot id: A0A192D1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1112:A9D12 RS11170
gene id: 1112:A9D12_RS11170
uniprot id: A0A192D5V6
names: Similarity
messages: Belongs to the peptidase U62 family.

1112:A9D12 RS08730
gene id: 1112:A9D12_RS08730
uniprot id: A0A192D5F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1112:A9D12 RS13155
gene id: 1112:A9D12_RS13155
uniprot id: A0A192D7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1112:A9D12 RS12490
gene id: 1112:A9D12_RS12490
uniprot id: A0A192D555
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1112:A9D12 RS10315
gene id: 1112:A9D12_RS10315
uniprot id: A0A192D668
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1112:A9D12 RS07675
gene id: 1112:A9D12_RS07675
uniprot id: A0A192D4Z0
names: Similarity
messages: Belongs to the UPF0178 family.

1112:A9D12 RS09245
gene id: 1112:A9D12_RS09245
uniprot id: A0A192D5M8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1112:A9D12 RS13785
gene id: 1112:A9D12_RS13785
uniprot id: A0A192D743
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS10380
gene id: 1112:A9D12_RS10380
uniprot id: A0A192D471
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1112:A9D12 RS10325
gene id: 1112:A9D12_RS10325
uniprot id: A0A192D704
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1112:A9D12 RS12035
gene id: 1112:A9D12_RS12035
uniprot id: A0A192D6Z2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1112:A9D12 RS02945
gene id: 1112:A9D12_RS02945
uniprot id: A0A192D293
names: Similarity
messages: Belongs to the pyruvate kinase family.

1112:A9D12 RS02995
gene id: 1112:A9D12_RS02995
uniprot id: A0A192D256
names: Similarity
messages: Belongs to the aspartokinase family.

1112:A9D12 RS13895
gene id: 1112:A9D12_RS13895
uniprot id: A0A192D7M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1112:A9D12 RS02380
gene id: 1112:A9D12_RS02380
uniprot id: A0A192D2I3
names: Similarity
messages: Belongs to the Tim44 family.

1112:A9D12 RS14125
gene id: 1112:A9D12_RS14125
uniprot id: A0A192D818
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS03035
gene id: 1112:A9D12_RS03035
uniprot id: A0A192D2B1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12205
gene id: 1112:A9D12_RS12205
uniprot id: A0A192D648
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1112:A9D12 RS12535
gene id: 1112:A9D12_RS12535
uniprot id: A0A192D693
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1112:A9D12 RS03095
gene id: 1112:A9D12_RS03095
uniprot id: A0A192D2V4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1112:A9D12 RS11710
gene id: 1112:A9D12_RS11710
uniprot id: A0A192D4S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1112:A9D12 RS04115
gene id: 1112:A9D12_RS04115
uniprot id: A0A192D174
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1112:A9D12 RS03220
gene id: 1112:A9D12_RS03220
uniprot id: A0A192D2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1112:A9D12 RS05570
gene id: 1112:A9D12_RS05570
uniprot id: A0A192D413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1112:A9D12 RS07145
gene id: 1112:A9D12_RS07145
uniprot id: A0A192D412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1112:A9D12 RS13820
gene id: 1112:A9D12_RS13820
uniprot id: A0A192D7L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1112:A9D12 RS10610
gene id: 1112:A9D12_RS10610
uniprot id: A0A192D611
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1112:A9D12 RS09530
gene id: 1112:A9D12_RS09530
uniprot id: A0A192D536
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS13430
gene id: 1112:A9D12_RS13430
uniprot id: A0A192D7N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1112:A9D12 RS02110
gene id: 1112:A9D12_RS02110
uniprot id: A0A192D2F0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1112:A9D12 RS00495
gene id: 1112:A9D12_RS00495
uniprot id: A0A192CZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1112:A9D12 RS03650
gene id: 1112:A9D12_RS03650
uniprot id: A0A192D238
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1112:A9D12 RS10875
gene id: 1112:A9D12_RS10875
uniprot id: A0A192D5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1112:A9D12 RS01365
gene id: 1112:A9D12_RS01365
uniprot id: A0A192CZY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1112:A9D12 RS04975
gene id: 1112:A9D12_RS04975
uniprot id: A0A192D333
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1112:A9D12 RS11515
gene id: 1112:A9D12_RS11515
uniprot id: A0A192D4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1112:A9D12 RS03635
gene id: 1112:A9D12_RS03635
uniprot id: A0A192D0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1112:A9D12 RS01560
gene id: 1112:A9D12_RS01560
uniprot id: A0A192D1L7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1112:A9D12 RS06125
gene id: 1112:A9D12_RS06125
uniprot id: A0A192D3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1112:A9D12 RS06430
gene id: 1112:A9D12_RS06430
uniprot id: A0A192D2D1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1112:A9D12 RS04345
gene id: 1112:A9D12_RS04345
uniprot id: A0A192D2Z1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1112:A9D12 RS04585
gene id: 1112:A9D12_RS04585
uniprot id: A0A192D3L7
names: Similarity
messages: Belongs to the HesB/IscA family.

1112:A9D12 RS04475
gene id: 1112:A9D12_RS04475
uniprot id: A0A192D8J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1112:A9D12 RS06655
gene id: 1112:A9D12_RS06655
uniprot id: A0A192D4H1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1112:A9D12 RS04145
gene id: 1112:A9D12_RS04145
uniprot id: A0A192D3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1112:A9D12 RS10495
gene id: 1112:A9D12_RS10495
uniprot id: A0A192D5Y9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1112:A9D12 RS08580
gene id: 1112:A9D12_RS08580
uniprot id: A0A192D4N4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS05340
gene id: 1112:A9D12_RS05340
uniprot id: A0A192D391
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1112:A9D12 RS06305
gene id: 1112:A9D12_RS06305
uniprot id: A0A192D3Y6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1112:A9D12 RS10880
gene id: 1112:A9D12_RS10880
uniprot id: A0A192D5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1112:A9D12 RS07280
gene id: 1112:A9D12_RS07280
uniprot id: A0A192D4S1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1112:A9D12 RS13310
gene id: 1112:A9D12_RS13310
uniprot id: A0A192D7C2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1112:A9D12 RS00215
gene id: 1112:A9D12_RS00215
uniprot id: A0A192D0F6
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1112:A9D12 RS04550
gene id: 1112:A9D12_RS04550
uniprot id: A0A192D331
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1112:A9D12 RS03410
gene id: 1112:A9D12_RS03410
uniprot id: A0A192D2C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS01335
gene id: 1112:A9D12_RS01335
uniprot id: A0A192D1H9
names: Similarity
messages: Belongs to the PucC family.

1112:A9D12 RS06105
gene id: 1112:A9D12_RS06105
uniprot id: A0A192D3L0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1112:A9D12 RS06835
gene id: 1112:A9D12_RS06835
uniprot id: A0A192D3W4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1112:A9D12 RS10225
gene id: 1112:A9D12_RS10225
uniprot id: A0A192D5U7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1112:A9D12 RS13275
gene id: 1112:A9D12_RS13275
uniprot id: A0A192D6M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS00275
gene id: 1112:A9D12_RS00275
uniprot id: A0A192D108
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS03355
gene id: 1112:A9D12_RS03355
uniprot id: A0A192D1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1112:A9D12 RS00885
gene id: 1112:A9D12_RS00885
uniprot id: A0A192D1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS12235
gene id: 1112:A9D12_RS12235
uniprot id: A0A192D653
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS06330
gene id: 1112:A9D12_RS06330
uniprot id: A0A192D3Z1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1112:A9D12 RS12620
gene id: 1112:A9D12_RS12620
uniprot id: A0A192D6A6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1112:A9D12 RS01200
gene id: 1112:A9D12_RS01200
uniprot id: A0A192D0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS13840
gene id: 1112:A9D12_RS13840
uniprot id: A0A192D753
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1112:A9D12 RS09400
gene id: 1112:A9D12_RS09400
uniprot id: A0A192D5Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1112:A9D12 RS01305
gene id: 1112:A9D12_RS01305
uniprot id: A0A192CZX0
names: Function
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS05605
gene id: 1112:A9D12_RS05605
uniprot id: A0A192D3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1112:A9D12 RS05885
gene id: 1112:A9D12_RS05885
uniprot id: A0A192D3H7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1112:A9D12 RS13775
gene id: 1112:A9D12_RS13775
uniprot id: A0A192D7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1112:A9D12 RS13770
gene id: 1112:A9D12_RS13770
uniprot id: A0A192D5R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1112:A9D12 RS06345
gene id: 1112:A9D12_RS06345
uniprot id: A0A192D3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS00265
gene id: 1112:A9D12_RS00265
uniprot id: A0A192D1M5
names: Similarity
messages: Belongs to the PhoH family.

1112:A9D12 RS02470
gene id: 1112:A9D12_RS02470
uniprot id: A0A192D0F1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1112:A9D12 RS04105
gene id: 1112:A9D12_RS04105
uniprot id: A0A192D2P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1112:A9D12 RS04480
gene id: 1112:A9D12_RS04480
uniprot id: A0A192D3J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1112:A9D12 RS02860
gene id: 1112:A9D12_RS02860
uniprot id: A0A192D232
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1112:A9D12 RS07785
gene id: 1112:A9D12_RS07785
uniprot id: A0A192D4P3
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1112:A9D12 RS10250
gene id: 1112:A9D12_RS10250
uniprot id: A0A192D5V3
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1112:A9D12 RS12765
gene id: 1112:A9D12_RS12765
uniprot id: A0A192D6L2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1112:A9D12 RS02235
gene id: 1112:A9D12_RS02235
uniprot id: A0A192D1U9
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS03900
gene id: 1112:A9D12_RS03900
uniprot id: A0A192D287
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1112:A9D12 RS06785
gene id: 1112:A9D12_RS06785
uniprot id: A0A192D2J0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS05080
gene id: 1112:A9D12_RS05080
uniprot id: A0A192D352
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1112:A9D12 RS03795
gene id: 1112:A9D12_RS03795
uniprot id: A0A192D123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1112:A9D12 RS06810
gene id: 1112:A9D12_RS06810
uniprot id: A0A192D487
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1112:A9D12 RS13485
gene id: 1112:A9D12_RS13485
uniprot id: A0A192D7P7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1112:A9D12 RS03140
gene id: 1112:A9D12_RS03140
uniprot id: A0A192D280
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1112:A9D12 RS07915
gene id: 1112:A9D12_RS07915
uniprot id: A0A192D527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1112:A9D12 RS02140
gene id: 1112:A9D12_RS02140
uniprot id: A0A192D1D7
names: Function
messages: Multidrug efflux pump.

1112:A9D12 RS03865
gene id: 1112:A9D12_RS03865
uniprot id: A0A192D8H9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1112:A9D12 RS00960
gene id: 1112:A9D12_RS00960
uniprot id: A0A192D0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1112:A9D12 RS09700
gene id: 1112:A9D12_RS09700
uniprot id: A0A192D3X1
names: Similarity
messages: Belongs to the AHA1 family.

1112:A9D12 RS11350
gene id: 1112:A9D12_RS11350
uniprot id: A0A192D4L5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1112:A9D12 RS07995
gene id: 1112:A9D12_RS07995
uniprot id: A0A192D4E5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1112:A9D12 RS10515
gene id: 1112:A9D12_RS10515
uniprot id: A0A192D5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1112:A9D12 RS01330
gene id: 1112:A9D12_RS01330
uniprot id: A0A192D1G7
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

1112:A9D12 RS00200
gene id: 1112:A9D12_RS00200
uniprot id: A0A192D0Z8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1112:A9D12 RS10795
gene id: 1112:A9D12_RS10795
uniprot id: A0A192D6F0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1112:A9D12 RS01825
gene id: 1112:A9D12_RS01825
uniprot id: A0A192D2A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1112:A9D12 RS05515
gene id: 1112:A9D12_RS05515
uniprot id: A0A192D8M6
names: Similarity
messages: Belongs to the peptidase M24B family.

1112:A9D12 RS07590
gene id: 1112:A9D12_RS07590
uniprot id: A0A192D837
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS14005
gene id: 1112:A9D12_RS14005
uniprot id: A0A192D5V9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1112:A9D12 RS03805
gene id: 1112:A9D12_RS03805
uniprot id: A0A192D270
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1112:A9D12 RS08765
gene id: 1112:A9D12_RS08765
uniprot id: A0A192D4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1112:A9D12 RS12625
gene id: 1112:A9D12_RS12625
uniprot id: A0A192D6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS11690
gene id: 1112:A9D12_RS11690
uniprot id: A0A192D888
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS04295
gene id: 1112:A9D12_RS04295
uniprot id: A0A192D7T0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1112:A9D12 RS03730
gene id: 1112:A9D12_RS03730
uniprot id: A0A192D253
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1112:A9D12 RS11725
gene id: 1112:A9D12_RS11725
uniprot id: A0A192D5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1112:A9D12 RS00855
gene id: 1112:A9D12_RS00855
uniprot id: A0A192D789
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1112:A9D12 RS07765
gene id: 1112:A9D12_RS07765
uniprot id: A0A192D2Z8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1112:A9D12 RS11870
gene id: 1112:A9D12_RS11870
uniprot id: A0A192D8Z7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1112:A9D12 RS03595
gene id: 1112:A9D12_RS03595
uniprot id: A0A192D228
names: Similarity
messages: Belongs to the cytochrome P450 family.

1112:A9D12 RS00140
gene id: 1112:A9D12_RS00140
uniprot id: A0A192D1L0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1112:A9D12 RS02800
gene id: 1112:A9D12_RS02800
uniprot id: A0A192D1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1112:A9D12 RS01515
gene id: 1112:A9D12_RS01515
uniprot id: A0A192D681
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1112:A9D12 RS08775
gene id: 1112:A9D12_RS08775
uniprot id: A0A192D3G5
names: Similarity
messages: Belongs to the peptidase M17 family.

1112:A9D12 RS13000
gene id: 1112:A9D12_RS13000
uniprot id: A0A192D6Q4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS08470
gene id: 1112:A9D12_RS08470
uniprot id: A0A192D4L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1112:A9D12 RS12645
gene id: 1112:A9D12_RS12645
uniprot id: A0A192D7A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS02485
gene id: 1112:A9D12_RS02485
uniprot id: A0A192D1Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1112:A9D12 RS02240
gene id: 1112:A9D12_RS02240
uniprot id: A0A192D832
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1112:A9D12 RS06010
gene id: 1112:A9D12_RS06010
uniprot id: A0A192D393
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1112:A9D12 RS10590
gene id: 1112:A9D12_RS10590
uniprot id: A0A192D4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1112:A9D12 RS08440
gene id: 1112:A9D12_RS08440
uniprot id: A0A192D4K8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS06725
gene id: 1112:A9D12_RS06725
uniprot id: A0A192D454
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1112:A9D12 RS13300
gene id: 1112:A9D12_RS13300
uniprot id: A0A192D6N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1112:A9D12 RS03270
gene id: 1112:A9D12_RS03270
uniprot id: A0A192D2Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1112:A9D12 RS01790
gene id: 1112:A9D12_RS01790
uniprot id: A0A192D052
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1112:A9D12 RS00550
gene id: 1112:A9D12_RS00550
uniprot id: A0A192CZK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1112:A9D12 RS12720
gene id: 1112:A9D12_RS12720
uniprot id: A0A192D590
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1112:A9D12 RS11775
gene id: 1112:A9D12_RS11775
uniprot id: A0A192D6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1112:A9D12 RS05850
gene id: 1112:A9D12_RS05850
uniprot id: A0A192D3H3
names: Similarity
messages: Belongs to the YggT family.

1112:A9D12 RS13830
gene id: 1112:A9D12_RS13830
uniprot id: A0A192D7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1112:A9D12 RS09795
gene id: 1112:A9D12_RS09795
uniprot id: A0A192D5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS01900
gene id: 1112:A9D12_RS01900
uniprot id: A0A192D1Q5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1112:A9D12 RS01375
gene id: 1112:A9D12_RS01375
uniprot id: A0A192D0Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS00730
gene id: 1112:A9D12_RS00730
uniprot id: A0A192CZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS11585
gene id: 1112:A9D12_RS11585
uniprot id: A0A192D5U8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1112:A9D12 RS12110
gene id: 1112:A9D12_RS12110
uniprot id: A0A192D4Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1112:A9D12 RS12115
gene id: 1112:A9D12_RS12115
uniprot id: A0A192D710
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1112:A9D12 RS13570
gene id: 1112:A9D12_RS13570
uniprot id: A0A192D7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1112:A9D12 RS07625
gene id: 1112:A9D12_RS07625
uniprot id: A0A192D4L9
names: Similarity
messages: Belongs to the LOG family.

1112:A9D12 RS12310
gene id: 1112:A9D12_RS12310
uniprot id: A0A192D6U7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1112:A9D12 RS13290
gene id: 1112:A9D12_RS13290
uniprot id: A0A192D5J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1112:A9D12 RS07570
gene id: 1112:A9D12_RS07570
uniprot id: A0A192D4K9
names: Similarity
messages: Belongs to the Dps family.

1112:A9D12 RS08880
gene id: 1112:A9D12_RS08880
uniprot id: A0A192D5H8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS01040
gene id: 1112:A9D12_RS01040
uniprot id: A0A192CZT1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02655
gene id: 1112:A9D12_RS02655
uniprot id: A0A192D6C0
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1112:A9D12 RS08545
gene id: 1112:A9D12_RS08545
uniprot id: A0A192D4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1112:A9D12 RS13740
gene id: 1112:A9D12_RS13740
uniprot id: A0A192D7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1112:A9D12 RS09160
gene id: 1112:A9D12_RS09160
uniprot id: A0A192D5B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1112:A9D12 RS10375
gene id: 1112:A9D12_RS10375
uniprot id: A0A192D5W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1112:A9D12 RS13225
gene id: 1112:A9D12_RS13225
uniprot id: A0A192D6L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1112:A9D12 RS09370
gene id: 1112:A9D12_RS09370
uniprot id: A0A192D5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1112:A9D12 RS09625
gene id: 1112:A9D12_RS09625
uniprot id: A0A192D549
names: Similarity
messages: Belongs to the universal stress protein A family.

1112:A9D12 RS02080
gene id: 1112:A9D12_RS02080
uniprot id: A0A192D096
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1112:A9D12 RS04020
gene id: 1112:A9D12_RS04020
uniprot id: A0A192D2A8
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1112:A9D12 RS11605
gene id: 1112:A9D12_RS11605
uniprot id: A0A192D4Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1112:A9D12 RS12775
gene id: 1112:A9D12_RS12775
uniprot id: A0A192D5A0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1112:A9D12 RS12345
gene id: 1112:A9D12_RS12345
uniprot id: A0A192D749
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1112:A9D12 RS13925
gene id: 1112:A9D12_RS13925
uniprot id: A0A192D5U5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1112:A9D12 RS09570
gene id: 1112:A9D12_RS09570
uniprot id: A0A192D5I1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1112:A9D12 RS04005
gene id: 1112:A9D12_RS04005
uniprot id: A0A192D2T1
names: Similarity
messages: Belongs to the AAA ATPase family.

1112:A9D12 RS12610
gene id: 1112:A9D12_RS12610
uniprot id: A0A192D574
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1112:A9D12 RS09250
gene id: 1112:A9D12_RS09250
uniprot id: A0A192D4U4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1112:A9D12 RS04705
gene id: 1112:A9D12_RS04705
uniprot id: A0A192D2Z2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1112:A9D12 RS07645
gene id: 1112:A9D12_RS07645
uniprot id: A0A192D4Y5
names: Similarity
messages: Belongs to the MipA/OmpV family.

1112:A9D12 RS03725
gene id: 1112:A9D12_RS03725
uniprot id: A0A192D7S1
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS13580
gene id: 1112:A9D12_RS13580
uniprot id: A0A192D7R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1112:A9D12 RS00605
gene id: 1112:A9D12_RS00605
uniprot id: A0A192D161
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS00665
gene id: 1112:A9D12_RS00665
uniprot id: A0A192D176
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1112:A9D12 RS08700
gene id: 1112:A9D12_RS08700
uniprot id: A0A192D5F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1112:A9D12 RS09015
gene id: 1112:A9D12_RS09015
uniprot id: A0A192D4Q7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1112:A9D12 RS11685
gene id: 1112:A9D12_RS11685
uniprot id: A0A192D986
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1112:A9D12 RS06560
gene id: 1112:A9D12_RS06560
uniprot id: A0A192D4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1112:A9D12 RS08930
gene id: 1112:A9D12_RS08930
uniprot id: A0A192D3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1112:A9D12 RS05195
gene id: 1112:A9D12_RS05195
uniprot id: A0A192D1R8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1112:A9D12 RS07790
gene id: 1112:A9D12_RS07790
uniprot id: A0A192D303
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS11955
gene id: 1112:A9D12_RS11955
uniprot id: A0A192D6X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1112:A9D12 RS09360
gene id: 1112:A9D12_RS09360
uniprot id: A0A192D5E4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1112:A9D12 RS06975
gene id: 1112:A9D12_RS06975
uniprot id: A0A192D4M2
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS05780
gene id: 1112:A9D12_RS05780
uniprot id: A0A192D222
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1112:A9D12 RS04170
gene id: 1112:A9D12_RS04170
uniprot id: A0A192D3E1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1112:A9D12 RS07000
gene id: 1112:A9D12_RS07000
uniprot id: A0A192D2M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1112:A9D12 RS01370
gene id: 1112:A9D12_RS01370
uniprot id: A0A192D241
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

1112:A9D12 RS09430
gene id: 1112:A9D12_RS09430
uniprot id: A0A192D5Q7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1112:A9D12 RS11485
gene id: 1112:A9D12_RS11485
uniprot id: A0A192D6Q6
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS05500
gene id: 1112:A9D12_RS05500
uniprot id: A0A192D1X2
names: Function
messages: Acts on leucine, isoleucine and valine.

1112:A9D12 RS14335
gene id: 1112:A9D12_RS14335
uniprot id: A0A192D7V7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1112:A9D12 RS02990
gene id: 1112:A9D12_RS02990
uniprot id: A0A192D1S3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1112:A9D12 RS13340
gene id: 1112:A9D12_RS13340
uniprot id: A0A192D6W5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1112:A9D12 RS04545
gene id: 1112:A9D12_RS04545
uniprot id: A0A192D2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1112:A9D12 RS02445
gene id: 1112:A9D12_RS02445
uniprot id: A0A192D6B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1112:A9D12 RS06035
gene id: 1112:A9D12_RS06035
uniprot id: A0A192D398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1112:A9D12 RS03970
gene id: 1112:A9D12_RS03970
uniprot id: A0A192D2L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS10460
gene id: 1112:A9D12_RS10460
uniprot id: A0A192D5Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1112:A9D12 RS13960
gene id: 1112:A9D12_RS13960
uniprot id: A0A192D700
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1112:A9D12 RS05475
gene id: 1112:A9D12_RS05475
uniprot id: A0A192D1W7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1112:A9D12 RS11030
gene id: 1112:A9D12_RS11030
uniprot id: A0A192D859
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1112:A9D12 RS07740
gene id: 1112:A9D12_RS07740
uniprot id: A0A192D8K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1112:A9D12 RS13825
gene id: 1112:A9D12_RS13825
uniprot id: A0A192D5S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1112:A9D12 RS01770
gene id: 1112:A9D12_RS01770
uniprot id: A0A192D177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS11090
gene id: 1112:A9D12_RS11090
uniprot id: A0A192D5U6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1112:A9D12 RS06600
gene id: 1112:A9D12_RS06600
uniprot id: A0A192D3J1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1112:A9D12 RS03820
gene id: 1112:A9D12_RS03820
uniprot id: A0A192D130
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1112:A9D12 RS10770
gene id: 1112:A9D12_RS10770
uniprot id: A0A192D5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1112:A9D12 RS11055
gene id: 1112:A9D12_RS11055
uniprot id: A0A192D5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1112:A9D12 RS07365
gene id: 1112:A9D12_RS07365
uniprot id: A0A192D2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1112:A9D12 RS08655
gene id: 1112:A9D12_RS08655
uniprot id: A0A192D4P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1112:A9D12 RS12780
gene id: 1112:A9D12_RS12780
uniprot id: A0A192D7C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1112:A9D12 RS07585
gene id: 1112:A9D12_RS07585
uniprot id: A0A192D3Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1112:A9D12 RS10835
gene id: 1112:A9D12_RS10835
uniprot id: A0A192D5J9
names: Similarity
messages: Belongs to the DprA/Smf family.

1112:A9D12 RS05485
gene id: 1112:A9D12_RS05485
uniprot id: A0A192D307
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1112:A9D12 RS05265
gene id: 1112:A9D12_RS05265
uniprot id: A0A192D1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS00325
gene id: 1112:A9D12_RS00325
uniprot id: A0A192CZG8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1112:A9D12 RS04300
gene id: 1112:A9D12_RS04300
uniprot id: A0A192D2S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1112:A9D12 RS06690
gene id: 1112:A9D12_RS06690
uniprot id: A0A192D6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1112:A9D12 RS01570
gene id: 1112:A9D12_RS01570
uniprot id: A0A192D272
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1112:A9D12 RS07465
gene id: 1112:A9D12_RS07465
uniprot id: A0A192D4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1112:A9D12 RS10960
gene id: 1112:A9D12_RS10960
uniprot id: A0A192D5L4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS10015
gene id: 1112:A9D12_RS10015
uniprot id: A0A192D5C7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1112:A9D12 RS12435
gene id: 1112:A9D12_RS12435
uniprot id: A0A192D6F9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1112:A9D12 RS07845
gene id: 1112:A9D12_RS07845
uniprot id: A0A192D313
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1112:A9D12 RS04530
gene id: 1112:A9D12_RS04530
uniprot id: A0A192D1F1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1112:A9D12 RS01165
gene id: 1112:A9D12_RS01165
uniprot id: A0A192D0V4
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

1112:A9D12 RS10045
gene id: 1112:A9D12_RS10045
uniprot id: A0A192D571
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1112:A9D12 RS07930
gene id: 1112:A9D12_RS07930
uniprot id: A0A192D4D7
names: Subunit
messages: Homodimer.

1112:A9D12 RS10090
gene id: 1112:A9D12_RS10090
uniprot id: A0A192D5S7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS13530
gene id: 1112:A9D12_RS13530
uniprot id: A0A192D6Z5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1112:A9D12 RS06820
gene id: 1112:A9D12_RS06820
uniprot id: A0A192D2J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1112:A9D12 RS02025
gene id: 1112:A9D12_RS02025
uniprot id: A0A192D1S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1112:A9D12 RS12165
gene id: 1112:A9D12_RS12165
uniprot id: A0A192D4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1112:A9D12 RS04760
gene id: 1112:A9D12_RS04760
uniprot id: A0A192D301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1112:A9D12 RS00600
gene id: 1112:A9D12_RS00600
uniprot id: A0A192D0L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1112:A9D12 RS09885
gene id: 1112:A9D12_RS09885
uniprot id: A0A192D552
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1112:A9D12 RS13455
gene id: 1112:A9D12_RS13455
uniprot id: A0A192D7P2
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS02635
gene id: 1112:A9D12_RS02635
uniprot id: A0A192D1K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1112:A9D12 RS13540
gene id: 1112:A9D12_RS13540
uniprot id: A0A192D5M6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1112:A9D12 RS10690
gene id: 1112:A9D12_RS10690
uniprot id: A0A192D5N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS09760
gene id: 1112:A9D12_RS09760
uniprot id: A0A192D3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1112:A9D12 RS10245
gene id: 1112:A9D12_RS10245
uniprot id: A0A192D5G7
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS00115
gene id: 1112:A9D12_RS00115
uniprot id: A0A192D0E2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS02850
gene id: 1112:A9D12_RS02850
uniprot id: A0A192D2Q7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1112:A9D12 RS13815
gene id: 1112:A9D12_RS13815
uniprot id: A0A192D748
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1112:A9D12 RS10330
gene id: 1112:A9D12_RS10330
uniprot id: A0A192D5H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1112:A9D12 RS08800
gene id: 1112:A9D12_RS08800
uniprot id: A0A192D563
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1112:A9D12 RS04120
gene id: 1112:A9D12_RS04120
uniprot id: A0A192D3D1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1112:A9D12 RS04270
gene id: 1112:A9D12_RS04270
uniprot id: A0A192D1A5
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS12160
gene id: 1112:A9D12_RS12160
uniprot id: A0A192D6S4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1112:A9D12 RS10560
gene id: 1112:A9D12_RS10560
uniprot id: A0A192D4A1
names: Similarity
messages: Belongs to the Skp family.

1112:A9D12 RS02580
gene id: 1112:A9D12_RS02580
uniprot id: A0A192D1J8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1112:A9D12 RS03855
gene id: 1112:A9D12_RS03855
uniprot id: A0A192D6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS10965
gene id: 1112:A9D12_RS10965
uniprot id: A0A192D5T0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1112:A9D12 RS12335
gene id: 1112:A9D12_RS12335
uniprot id: A0A192D6V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1112:A9D12 RS12730
gene id: 1112:A9D12_RS12730
uniprot id: A0A192D6C6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1112:A9D12 RS02570
gene id: 1112:A9D12_RS02570
uniprot id: A0A192D0G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1112:A9D12 RS06450
gene id: 1112:A9D12_RS06450
uniprot id: A0A192D3Q7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1112:A9D12 RS01505
gene id: 1112:A9D12_RS01505
uniprot id: A0A192D262
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1112:A9D12 RS13335
gene id: 1112:A9D12_RS13335
uniprot id: A0A192D8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1112:A9D12 RS11570
gene id: 1112:A9D12_RS11570
uniprot id: A0A192D6H8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1112:A9D12 RS04175
gene id: 1112:A9D12_RS04175
uniprot id: A0A192D2D8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1112:A9D12 RS07775
gene id: 1112:A9D12_RS07775
uniprot id: A0A192D424
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1112:A9D12 RS13235
gene id: 1112:A9D12_RS13235
uniprot id: A0A192D7A5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1112:A9D12 RS02865
gene id: 1112:A9D12_RS02865
uniprot id: A0A192D278
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1112:A9D12 RS09120
gene id: 1112:A9D12_RS09120
uniprot id: A0A192D6W0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1112:A9D12 RS12555
gene id: 1112:A9D12_RS12555
uniprot id: A0A192D786
names: Similarity
messages: Belongs to the citrate synthase family.

1112:A9D12 RS05400
gene id: 1112:A9D12_RS05400
uniprot id: A0A192D3Y2
names: Similarity
messages: Belongs to the peptidase M13 family.

1112:A9D12 RS04665
gene id: 1112:A9D12_RS04665
uniprot id: A0A192D3M3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1112:A9D12 RS02590
gene id: 1112:A9D12_RS02590
uniprot id: A0A192D1Z6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1112:A9D12 RS14355
gene id: 1112:A9D12_RS14355
uniprot id: A0A192D765
names: Subcellular Location Annotation
messages: Membrane

1112:A9D12 RS07295
gene id: 1112:A9D12_RS07295
uniprot id: A0A192D4G2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1112:A9D12 RS10070
gene id: 1112:A9D12_RS10070
uniprot id: A0A192D633
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1112:A9D12 RS13715
gene id: 1112:A9D12_RS13715
uniprot id: A0A192D5Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1112:A9D12 RS02320
gene id: 1112:A9D12_RS02320
uniprot id: A0A192D6A7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1112:A9D12 RS04395
gene id: 1112:A9D12_RS04395
uniprot id: A0A192D2H4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1112:A9D12 RS12600
gene id: 1112:A9D12_RS12600
uniprot id: A0A192D6I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS13810
gene id: 1112:A9D12_RS13810
uniprot id: A0A192D6W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1112:A9D12 RS14195
gene id: 1112:A9D12_RS14195
uniprot id: A0A192D7T2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1112:A9D12 RS09660
gene id: 1112:A9D12_RS09660
uniprot id: A0A192D554
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1112:A9D12 RS03985
gene id: 1112:A9D12_RS03985
uniprot id: A0A192D885
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1112:A9D12 RS09255
gene id: 1112:A9D12_RS09255
uniprot id: A0A192D4Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1112:A9D12 RS00230
gene id: 1112:A9D12_RS00230
uniprot id: A0A192CZF3
names: Similarity
messages: Belongs to the ros/MucR family.

1112:A9D12 RS12200
gene id: 1112:A9D12_RS12200
uniprot id: A0A192D725
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1112:A9D12 RS03600
gene id: 1112:A9D12_RS03600
uniprot id: A0A192D2F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS02750
gene id: 1112:A9D12_RS02750
uniprot id: A0A192D257
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1112:A9D12 RS02675
gene id: 1112:A9D12_RS02675
uniprot id: A0A192D2M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

1112:A9D12 RS00405
gene id: 1112:A9D12_RS00405
uniprot id: A0A192D134
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1112:A9D12 RS01710
gene id: 1112:A9D12_RS01710
uniprot id: A0A192D148
names: Similarity
messages: Belongs to the CopC family.

1112:A9D12 RS06405
gene id: 1112:A9D12_RS06405
uniprot id: A0A192D8Q7
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1112:A9D12 RS12760
gene id: 1112:A9D12_RS12760
uniprot id: A0A192D6D1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1112:A9D12 RS10605
gene id: 1112:A9D12_RS10605
uniprot id: A0A192D5L6
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1112:A9D12 RS06130
gene id: 1112:A9D12_RS06130
uniprot id: A0A192D3L8
names: Similarity
messages: Belongs to the type III secretion exporter family.

1112:A9D12 RS02555
gene id: 1112:A9D12_RS02555
uniprot id: A0A192D1J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1112:A9D12 RS01070
gene id: 1112:A9D12_RS01070
uniprot id: A0A192CZT6
names: Similarity
messages: Belongs to the sterol desaturase family.

1112:A9D12 RS08515
gene id: 1112:A9D12_RS08515
uniprot id: A0A192D5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1112:A9D12 RS08895
gene id: 1112:A9D12_RS08895
uniprot id: A0A192D577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1112:A9D12 RS09480
gene id: 1112:A9D12_RS09480
uniprot id: A0A192D5G5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1112:A9D12 RS09225
gene id: 1112:A9D12_RS09225
uniprot id: A0A192D4Y6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1112:A9D12 RS04925
gene id: 1112:A9D12_RS04925
uniprot id: A0A192D392
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1112:A9D12 RS06230
gene id: 1112:A9D12_RS06230
uniprot id: A0A192D3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1112:A9D12 RS09775
gene id: 1112:A9D12_RS09775
uniprot id: A0A192D592
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1112:A9D12 RS11805
gene id: 1112:A9D12_RS11805
uniprot id: A0A192D5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

1112:A9D12 RS12015
gene id: 1112:A9D12_RS12015
uniprot id: A0A192D682
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1112:A9D12 RS10920
gene id: 1112:A9D12_RS10920
uniprot id: A0A192D6H0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1112:A9D12 RS03505
gene id: 1112:A9D12_RS03505
uniprot id: A0A192D318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1112:A9D12 RS06325
gene id: 1112:A9D12_RS06325
uniprot id: A0A192D3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1112:A9D12 RS00475
gene id: 1112:A9D12_RS00475
uniprot id: A0A192D1Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1112:A9D12 RS13640
gene id: 1112:A9D12_RS13640
uniprot id: A0A192D6T3
names: Similarity
messages: Belongs to the CFA/CMAS family.