1091494:MEALZ RS14825
gene id: 1091494:MEALZ_RS14825
uniprot id: G4T2H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1091494:MEALZ RS04415
gene id: 1091494:MEALZ_RS04415
uniprot id: G4T3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS00810
gene id: 1091494:MEALZ_RS00810
uniprot id: G4SV83
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS14465
gene id: 1091494:MEALZ_RS14465
uniprot id: G4T1W0
names: Similarity
messages: Belongs to the glutamate synthase family.

1091494:MEALZ RS02695
gene id: 1091494:MEALZ_RS02695
uniprot id: G4SZ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1091494:MEALZ RS05515
gene id: 1091494:MEALZ_RS05515
uniprot id: G4SU00
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1091494:MEALZ RS01535
gene id: 1091494:MEALZ_RS01535
uniprot id: G4SWU7
names: Similarity
messages: Belongs to the YoeB family.

1091494:MEALZ RS00515
gene id: 1091494:MEALZ_RS00515
uniprot id: G4SUH9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1091494:MEALZ RS14885
gene id: 1091494:MEALZ_RS14885
uniprot id: G4T2I4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1091494:MEALZ RS09940
gene id: 1091494:MEALZ_RS09940
uniprot id: G4T3I7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1091494:MEALZ RS15650
gene id: 1091494:MEALZ_RS15650
uniprot id: G4T3R5
names: Similarity
messages: Belongs to the PhoH family.

1091494:MEALZ RS05050
gene id: 1091494:MEALZ_RS05050
uniprot id: G4ST19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1091494:MEALZ RS07745
gene id: 1091494:MEALZ_RS07745
uniprot id: G4SZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1091494:MEALZ RS19445
gene id: 1091494:MEALZ_RS19445
uniprot id: G4T0L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS10155
gene id: 1091494:MEALZ_RS10155
uniprot id: G4T421
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1091494:MEALZ RS12245
gene id: 1091494:MEALZ_RS12245
uniprot id: G4SWG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS15470
gene id: 1091494:MEALZ_RS15470
uniprot id: G4T3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1091494:MEALZ RS00785
gene id: 1091494:MEALZ_RS00785
uniprot id: G4SV78
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS14440
gene id: 1091494:MEALZ_RS14440
uniprot id: G4T1V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1091494:MEALZ RS13560
gene id: 1091494:MEALZ_RS13560
uniprot id: G4SZL3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1091494:MEALZ RS17275
gene id: 1091494:MEALZ_RS17275
uniprot id: G4SVV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS14935
gene id: 1091494:MEALZ_RS14935
uniprot id: G4T2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1091494:MEALZ RS05640
gene id: 1091494:MEALZ_RS05640
uniprot id: G4SUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1091494:MEALZ RS06325
gene id: 1091494:MEALZ_RS06325
uniprot id: G4SW71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1091494:MEALZ RS09725
gene id: 1091494:MEALZ_RS09725
uniprot id: G4T311
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1091494:MEALZ RS16960
gene id: 1091494:MEALZ_RS16960
uniprot id: G4SV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1091494:MEALZ RS07140
gene id: 1091494:MEALZ_RS07140
uniprot id: G4SXV6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1091494:MEALZ RS12270
gene id: 1091494:MEALZ_RS12270
uniprot id: G4SWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS15060
gene id: 1091494:MEALZ_RS15060
uniprot id: G4T2L7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1091494:MEALZ RS14285
gene id: 1091494:MEALZ_RS14285
uniprot id: G4T167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1091494:MEALZ RS10955
gene id: 1091494:MEALZ_RS10955
uniprot id: G4STG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1091494:MEALZ RS14750
gene id: 1091494:MEALZ_RS14750
uniprot id: G4T213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS09220
gene id: 1091494:MEALZ_RS09220
uniprot id: G4T2C6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1091494:MEALZ RS17855
gene id: 1091494:MEALZ_RS17855
uniprot id: G4SXD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1091494:MEALZ RS07820
gene id: 1091494:MEALZ_RS07820
uniprot id: G4SZF5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1091494:MEALZ RS04980
gene id: 1091494:MEALZ_RS04980
uniprot id: G4ST06
names: Similarity
messages: Belongs to the UPF0166 family.

1091494:MEALZ RS01975
gene id: 1091494:MEALZ_RS01975
uniprot id: G4SXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1091494:MEALZ RS11465
gene id: 1091494:MEALZ_RS11465
uniprot id: G4SUV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS15405
gene id: 1091494:MEALZ_RS15405
uniprot id: G4T377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1091494:MEALZ RS18450
gene id: 1091494:MEALZ_RS18450
uniprot id: G4SYA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS07650
gene id: 1091494:MEALZ_RS07650
uniprot id: G4SZB8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1091494:MEALZ RS19790
gene id: 1091494:MEALZ_RS19790
uniprot id: G4T1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1091494:MEALZ RS00845
gene id: 1091494:MEALZ_RS00845
uniprot id: G4SV89
names: Similarity
messages: Belongs to the UPF0145 family.

1091494:MEALZ RS15585
gene id: 1091494:MEALZ_RS15585
uniprot id: G4T3Q2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1091494:MEALZ RS15015
gene id: 1091494:MEALZ_RS15015
uniprot id: G4T2K8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1091494:MEALZ RS18800
gene id: 1091494:MEALZ_RS18800
uniprot id: G4SZ36
names: Similarity
messages: Belongs to the YoeB family.

1091494:MEALZ RS17195
gene id: 1091494:MEALZ_RS17195
uniprot id: G4SVT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1091494:MEALZ RS07125
gene id: 1091494:MEALZ_RS07125
uniprot id: G4SXV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1091494:MEALZ RS13075
gene id: 1091494:MEALZ_RS13075
uniprot id: G4SYQ6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1091494:MEALZ RS07405
gene id: 1091494:MEALZ_RS07405
uniprot id: G4SYM0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1091494:MEALZ RS11210
gene id: 1091494:MEALZ_RS11210
uniprot id: G4SU65
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1091494:MEALZ RS00050
gene id: 1091494:MEALZ_RS00050
uniprot id: G4STP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1091494:MEALZ RS18780
gene id: 1091494:MEALZ_RS18780
uniprot id: G4SZ29
names: Similarity
messages: Belongs to the asparaginase 1 family.

1091494:MEALZ RS16800
gene id: 1091494:MEALZ_RS16800
uniprot id: G4SUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1091494:MEALZ RS00500
gene id: 1091494:MEALZ_RS00500
uniprot id: G4SUH6
names: Similarity
messages: Belongs to the UPF0234 family.

1091494:MEALZ RS13110
gene id: 1091494:MEALZ_RS13110
uniprot id: G4SYR4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1091494:MEALZ RS02190
gene id: 1091494:MEALZ_RS02190
uniprot id: G4SYE4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1091494:MEALZ RS11365
gene id: 1091494:MEALZ_RS11365
uniprot id: G4SUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1091494:MEALZ RS13480
gene id: 1091494:MEALZ_RS13480
uniprot id: G4SZJ9
names: Similarity
messages: Belongs to the HesB/IscA family.

1091494:MEALZ RS15620
gene id: 1091494:MEALZ_RS15620
uniprot id: G4T3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1091494:MEALZ RS16350
gene id: 1091494:MEALZ_RS16350
uniprot id: G4STL4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1091494:MEALZ RS15395
gene id: 1091494:MEALZ_RS15395
uniprot id: G4T375
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1091494:MEALZ RS02875
gene id: 1091494:MEALZ_RS02875
uniprot id: G4SZZ4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17415
gene id: 1091494:MEALZ_RS17415
uniprot id: G4SVX5
names: Similarity
messages: Belongs to the RutC family.

1091494:MEALZ RS16180
gene id: 1091494:MEALZ_RS16180
uniprot id: G4STH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1091494:MEALZ RS11740
gene id: 1091494:MEALZ_RS11740
uniprot id: G4SVM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1091494:MEALZ RS08865
gene id: 1091494:MEALZ_RS08865
uniprot id: G4T1R4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1091494:MEALZ RS08845
gene id: 1091494:MEALZ_RS08845
uniprot id: G4T1R0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1091494:MEALZ RS14670
gene id: 1091494:MEALZ_RS14670
uniprot id: G4T1Z9
names: Subcellular Location Annotation
messages: Cytoplasm

1091494:MEALZ RS19920
gene id: 1091494:MEALZ_RS19920
uniprot id: G4T218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1091494:MEALZ RS07550
gene id: 1091494:MEALZ_RS07550
uniprot id: G4SYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1091494:MEALZ RS21030
gene id: 1091494:MEALZ_RS21030
uniprot id: G4SVS5
names: Subcellular Location Annotation
messages: Cell inner membrane

1091494:MEALZ RS21050
gene id: 1091494:MEALZ_RS21050
uniprot id: G4T0F8
names: Subcellular Location Annotation
messages: Cell inner membrane

1091494:MEALZ RS03290
gene id: 1091494:MEALZ_RS03290
uniprot id: G4T0U2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1091494:MEALZ RS19515
gene id: 1091494:MEALZ_RS19515
uniprot id: G4T0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS13345
gene id: 1091494:MEALZ_RS13345
uniprot id: G4SYW5
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS11330
gene id: 1091494:MEALZ_RS11330
uniprot id: G4SUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS15660
gene id: 1091494:MEALZ_RS15660
uniprot id: G4T3R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1091494:MEALZ RS16270
gene id: 1091494:MEALZ_RS16270
uniprot id: G4STJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1091494:MEALZ RS11355
gene id: 1091494:MEALZ_RS11355
uniprot id: G4SUT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS03770
gene id: 1091494:MEALZ_RS03770
uniprot id: G4T249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1091494:MEALZ RS12180
gene id: 1091494:MEALZ_RS12180
uniprot id: G4SWF5
names: Similarity
messages: Belongs to the FeoA family.

1091494:MEALZ RS16445
gene id: 1091494:MEALZ_RS16445
uniprot id: G4STM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1091494:MEALZ RS18190
gene id: 1091494:MEALZ_RS18190
uniprot id: G4SY56
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS15335
gene id: 1091494:MEALZ_RS15335
uniprot id: G4T364
names: Similarity
messages: Belongs to the peptidase M16 family.

1091494:MEALZ RS07600
gene id: 1091494:MEALZ_RS07600
uniprot id: G4SZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1091494:MEALZ RS00505
gene id: 1091494:MEALZ_RS00505
uniprot id: G4SUH7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1091494:MEALZ RS12660
gene id: 1091494:MEALZ_RS12660
uniprot id: G4SXB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1091494:MEALZ RS16355
gene id: 1091494:MEALZ_RS16355
uniprot id: G4STL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1091494:MEALZ RS13920
gene id: 1091494:MEALZ_RS13920
uniprot id: G4T0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1091494:MEALZ RS02160
gene id: 1091494:MEALZ_RS02160
uniprot id: G4SYD7
names: Similarity
messages: Belongs to the peptidase S41A family.

1091494:MEALZ RS02625
gene id: 1091494:MEALZ_RS02625
uniprot id: G4SZ83
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS01325
gene id: 1091494:MEALZ_RS01325
uniprot id: G4SW49
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1091494:MEALZ RS06650
gene id: 1091494:MEALZ_RS06650
uniprot id: G4SWZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1091494:MEALZ RS12820
gene id: 1091494:MEALZ_RS12820
uniprot id: G4SY00
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17325
gene id: 1091494:MEALZ_RS17325
uniprot id: G4SVW3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1091494:MEALZ RS21065
gene id: 1091494:MEALZ_RS21065
uniprot id: G4T160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS08780
gene id: 1091494:MEALZ_RS08780
uniprot id: G4T1P7
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1091494:MEALZ RS03310
gene id: 1091494:MEALZ_RS03310
uniprot id: G4T0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1091494:MEALZ RS16310
gene id: 1091494:MEALZ_RS16310
uniprot id: G4STK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1091494:MEALZ RS14880
gene id: 1091494:MEALZ_RS14880
uniprot id: G4T2I3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1091494:MEALZ RS18340
gene id: 1091494:MEALZ_RS18340
uniprot id: G4SY86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1091494:MEALZ RS11375
gene id: 1091494:MEALZ_RS11375
uniprot id: G4SUU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1091494:MEALZ RS09665
gene id: 1091494:MEALZ_RS09665
uniprot id: G4T2Z7
names: Similarity
messages: Belongs to the HypE family.

1091494:MEALZ RS16705
gene id: 1091494:MEALZ_RS16705
uniprot id: G4SUC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1091494:MEALZ RS19720
gene id: 1091494:MEALZ_RS19720
uniprot id: G4T1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS15180
gene id: 1091494:MEALZ_RS15180
uniprot id: G4T330
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1091494:MEALZ RS14400
gene id: 1091494:MEALZ_RS14400
uniprot id: G4T1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1091494:MEALZ RS02520
gene id: 1091494:MEALZ_RS02520
uniprot id: G4SZ59
names: Similarity
messages: Belongs to the UPF0047 family.

1091494:MEALZ RS17045
gene id: 1091494:MEALZ_RS17045
uniprot id: G4SV47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1091494:MEALZ RS17985
gene id: 1091494:MEALZ_RS17985
uniprot id: G4SXG1
names: Subunit
messages: Monomer.

1091494:MEALZ RS06555
gene id: 1091494:MEALZ_RS06555
uniprot id: G4SWB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1091494:MEALZ RS20620
gene id: 1091494:MEALZ_RS20620
uniprot id: G4T407
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS14555
gene id: 1091494:MEALZ_RS14555
uniprot id: G4T1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1091494:MEALZ RS18495
gene id: 1091494:MEALZ_RS18495
uniprot id: G4SYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1091494:MEALZ RS08045
gene id: 1091494:MEALZ_RS08045
uniprot id: G4T048
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1091494:MEALZ RS01195
gene id: 1091494:MEALZ_RS01195
uniprot id: G4SW21
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS10985
gene id: 1091494:MEALZ_RS10985
uniprot id: G4STG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS10710
gene id: 1091494:MEALZ_RS10710
uniprot id: G4STB9
names: Similarity
messages: Belongs to the pirin family.

1091494:MEALZ RS14430
gene id: 1091494:MEALZ_RS14430
uniprot id: G4T1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1091494:MEALZ RS06915
gene id: 1091494:MEALZ_RS06915
uniprot id: G4SX50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1091494:MEALZ RS03535
gene id: 1091494:MEALZ_RS03535
uniprot id: G4T1K3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1091494:MEALZ RS17945
gene id: 1091494:MEALZ_RS17945
uniprot id: G4SXF3
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS11910
gene id: 1091494:MEALZ_RS11910
uniprot id: G4SVQ7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1091494:MEALZ RS01345
gene id: 1091494:MEALZ_RS01345
uniprot id: G4SW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS15330
gene id: 1091494:MEALZ_RS15330
uniprot id: G4T363
names: Similarity
messages: Belongs to the peptidase M16 family.

1091494:MEALZ RS03610
gene id: 1091494:MEALZ_RS03610
uniprot id: G4T1L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1091494:MEALZ RS01610
gene id: 1091494:MEALZ_RS01610
uniprot id: G4SWW1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1091494:MEALZ RS07855
gene id: 1091494:MEALZ_RS07855
uniprot id: G4SZG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1091494:MEALZ RS05095
gene id: 1091494:MEALZ_RS05095
uniprot id: G4ST28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS00510
gene id: 1091494:MEALZ_RS00510
uniprot id: G4SUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS03035
gene id: 1091494:MEALZ_RS03035
uniprot id: G4T0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1091494:MEALZ RS02135
gene id: 1091494:MEALZ_RS02135
uniprot id: G4SYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1091494:MEALZ RS13340
gene id: 1091494:MEALZ_RS13340
uniprot id: G4SYW4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1091494:MEALZ RS06535
gene id: 1091494:MEALZ_RS06535
uniprot id: G4SWB4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS10010
gene id: 1091494:MEALZ_RS10010
uniprot id: G4T3K2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1091494:MEALZ RS04825
gene id: 1091494:MEALZ_RS04825
uniprot id: G4T3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1091494:MEALZ RS05650
gene id: 1091494:MEALZ_RS05650
uniprot id: G4SUM0
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1091494:MEALZ RS00395
gene id: 1091494:MEALZ_RS00395
uniprot id: G4SUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1091494:MEALZ RS09120
gene id: 1091494:MEALZ_RS09120
uniprot id: G4T2A6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1091494:MEALZ RS00925
gene id: 1091494:MEALZ_RS00925
uniprot id: G4SVA8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS02115
gene id: 1091494:MEALZ_RS02115
uniprot id: G4SYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1091494:MEALZ RS10805
gene id: 1091494:MEALZ_RS10805
uniprot id: G4T2F9
names: Similarity
messages: Belongs to the Fur family.

1091494:MEALZ RS10830
gene id: 1091494:MEALZ_RS10830
uniprot id: G4STD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1091494:MEALZ RS03250
gene id: 1091494:MEALZ_RS03250
uniprot id: G4T0T3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1091494:MEALZ RS19070
gene id: 1091494:MEALZ_RS19070
uniprot id: G4SZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1091494:MEALZ RS16105
gene id: 1091494:MEALZ_RS16105
uniprot id: G4T4F4
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1091494:MEALZ RS11340
gene id: 1091494:MEALZ_RS11340
uniprot id: G4SUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1091494:MEALZ RS17595
gene id: 1091494:MEALZ_RS17595
uniprot id: G4SWM2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1091494:MEALZ RS07630
gene id: 1091494:MEALZ_RS07630
uniprot id: G4SZB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19925
gene id: 1091494:MEALZ_RS19925
uniprot id: G4T219
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1091494:MEALZ RS16965
gene id: 1091494:MEALZ_RS16965
uniprot id: G4SV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1091494:MEALZ RS19510
gene id: 1091494:MEALZ_RS19510
uniprot id: G4T0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS14075
gene id: 1091494:MEALZ_RS14075
uniprot id: G4T125
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS07255
gene id: 1091494:MEALZ_RS07255
uniprot id: G4SYI8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1091494:MEALZ RS10975
gene id: 1091494:MEALZ_RS10975
uniprot id: G4STG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS11765
gene id: 1091494:MEALZ_RS11765
uniprot id: G4SVM6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1091494:MEALZ RS08800
gene id: 1091494:MEALZ_RS08800
uniprot id: G4T1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1091494:MEALZ RS14225
gene id: 1091494:MEALZ_RS14225
uniprot id: G4T155
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1091494:MEALZ RS06125
gene id: 1091494:MEALZ_RS06125
uniprot id: G4SVH4
names: Similarity
messages: Belongs to the ArsC family.

1091494:MEALZ RS03530
gene id: 1091494:MEALZ_RS03530
uniprot id: G4T1K2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1091494:MEALZ RS02485
gene id: 1091494:MEALZ_RS02485
uniprot id: G4SZ52
names: Similarity
messages: Belongs to the YfgM family.

1091494:MEALZ RS07150
gene id: 1091494:MEALZ_RS07150
uniprot id: G4SXV8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1091494:MEALZ RS06230
gene id: 1091494:MEALZ_RS06230
uniprot id: G4SVJ5
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1091494:MEALZ RS19965
gene id: 1091494:MEALZ_RS19965
uniprot id: G4T4G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1091494:MEALZ RS19385
gene id: 1091494:MEALZ_RS19385
uniprot id: G4T0K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1091494:MEALZ RS01200
gene id: 1091494:MEALZ_RS01200
uniprot id: G4SW22
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1091494:MEALZ RS06425
gene id: 1091494:MEALZ_RS06425
uniprot id: G4SW92
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1091494:MEALZ RS04925
gene id: 1091494:MEALZ_RS04925
uniprot id: G4T409
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1091494:MEALZ RS07495
gene id: 1091494:MEALZ_RS07495
uniprot id: G4SYN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1091494:MEALZ RS00350
gene id: 1091494:MEALZ_RS00350
uniprot id: G4STV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS02220
gene id: 1091494:MEALZ_RS02220
uniprot id: G4SYF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1091494:MEALZ RS02125
gene id: 1091494:MEALZ_RS02125
uniprot id: G4SYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1091494:MEALZ RS15735
gene id: 1091494:MEALZ_RS15735
uniprot id: G4T3T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS01925
gene id: 1091494:MEALZ_RS01925
uniprot id: G4SXN5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1091494:MEALZ RS08200
gene id: 1091494:MEALZ_RS08200
uniprot id: G4T081
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1091494:MEALZ RS11945
gene id: 1091494:MEALZ_RS11945
uniprot id: G4SVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1091494:MEALZ RS18875
gene id: 1091494:MEALZ_RS18875
uniprot id: G4SZQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS03270
gene id: 1091494:MEALZ_RS03270
uniprot id: G4T0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1091494:MEALZ RS07250
gene id: 1091494:MEALZ_RS07250
uniprot id: G4SXX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1091494:MEALZ RS01500
gene id: 1091494:MEALZ_RS01500
uniprot id: G4SWU0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1091494:MEALZ RS09820
gene id: 1091494:MEALZ_RS09820
uniprot id: G4T3G2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1091494:MEALZ RS08190
gene id: 1091494:MEALZ_RS08190
uniprot id: G4T079
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS08655
gene id: 1091494:MEALZ_RS08655
uniprot id: G4T1M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1091494:MEALZ RS23220
gene id: 1091494:MEALZ_RS23220
uniprot id: G4SX25
names: Similarity
messages: Belongs to the HsdR family.

1091494:MEALZ RS16600
gene id: 1091494:MEALZ_RS16600
uniprot id: G4SUA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1091494:MEALZ RS09425
gene id: 1091494:MEALZ_RS09425
uniprot id: G4T2V1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS03145
gene id: 1091494:MEALZ_RS03145
uniprot id: G4T0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1091494:MEALZ RS12685
gene id: 1091494:MEALZ_RS12685
uniprot id: G4SXB5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1091494:MEALZ RS11445
gene id: 1091494:MEALZ_RS11445
uniprot id: G4SUV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS02905
gene id: 1091494:MEALZ_RS02905
uniprot id: G4T002
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1091494:MEALZ RS12550
gene id: 1091494:MEALZ_RS12550
uniprot id: G4SX84
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1091494:MEALZ RS17400
gene id: 1091494:MEALZ_RS17400
uniprot id: G4SVX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS01860
gene id: 1091494:MEALZ_RS01860
uniprot id: G4SXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1091494:MEALZ RS02805
gene id: 1091494:MEALZ_RS02805
uniprot id: G4SZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1091494:MEALZ RS01600
gene id: 1091494:MEALZ_RS01600
uniprot id: G4SWV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1091494:MEALZ RS05975
gene id: 1091494:MEALZ_RS05975
uniprot id: G4SVE2
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS09770
gene id: 1091494:MEALZ_RS09770
uniprot id: G4T3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1091494:MEALZ RS18320
gene id: 1091494:MEALZ_RS18320
uniprot id: G4SY82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1091494:MEALZ RS11735
gene id: 1091494:MEALZ_RS11735
uniprot id: G4SVM0
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1091494:MEALZ RS20105
gene id: 1091494:MEALZ_RS20105
uniprot id: G4T4I9
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1091494:MEALZ RS02075
gene id: 1091494:MEALZ_RS02075
uniprot id: G4SYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS07615
gene id: 1091494:MEALZ_RS07615
uniprot id: G4SZB2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1091494:MEALZ RS05410
gene id: 1091494:MEALZ_RS05410
uniprot id: G4STY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1091494:MEALZ RS14615
gene id: 1091494:MEALZ_RS14615
uniprot id: G4T1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1091494:MEALZ RS09545
gene id: 1091494:MEALZ_RS09545
uniprot id: G4T2X4
names: Similarity
messages: Belongs to the VgrG protein family.

1091494:MEALZ RS06315
gene id: 1091494:MEALZ_RS06315
uniprot id: G4SW69
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1091494:MEALZ RS06985
gene id: 1091494:MEALZ_RS06985
uniprot id: G4SXS6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16265
gene id: 1091494:MEALZ_RS16265
uniprot id: G4STJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1091494:MEALZ RS16230
gene id: 1091494:MEALZ_RS16230
uniprot id: G4STI9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1091494:MEALZ RS01650
gene id: 1091494:MEALZ_RS01650
uniprot id: G4SWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1091494:MEALZ RS15820
gene id: 1091494:MEALZ_RS15820
uniprot id: G4T495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1091494:MEALZ RS11300
gene id: 1091494:MEALZ_RS11300
uniprot id: G4SUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1091494:MEALZ RS17835
gene id: 1091494:MEALZ_RS17835
uniprot id: G4SXD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1091494:MEALZ RS02430
gene id: 1091494:MEALZ_RS02430
uniprot id: G4SZ42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1091494:MEALZ RS07360
gene id: 1091494:MEALZ_RS07360
uniprot id: G4SYL0
names: Subcellular Location Annotation
messages: Cell inner membrane

1091494:MEALZ RS06910
gene id: 1091494:MEALZ_RS06910
uniprot id: G4SX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1091494:MEALZ RS19665
gene id: 1091494:MEALZ_RS19665
uniprot id: G4T1B1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1091494:MEALZ RS02000
gene id: 1091494:MEALZ_RS02000
uniprot id: G4SXP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1091494:MEALZ RS07190
gene id: 1091494:MEALZ_RS07190
uniprot id: G4SXW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1091494:MEALZ RS04800
gene id: 1091494:MEALZ_RS04800
uniprot id: G4T3Y0
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1091494:MEALZ RS18245
gene id: 1091494:MEALZ_RS18245
uniprot id: G4SY68
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1091494:MEALZ RS06770
gene id: 1091494:MEALZ_RS06770
uniprot id: G4SX20
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1091494:MEALZ RS16470
gene id: 1091494:MEALZ_RS16470
uniprot id: G4SU83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1091494:MEALZ RS18325
gene id: 1091494:MEALZ_RS18325
uniprot id: G4SY83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1091494:MEALZ RS02265
gene id: 1091494:MEALZ_RS02265
uniprot id: G4SYF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1091494:MEALZ RS16565
gene id: 1091494:MEALZ_RS16565
uniprot id: G4SUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1091494:MEALZ RS02825
gene id: 1091494:MEALZ_RS02825
uniprot id: G4SZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1091494:MEALZ RS11930
gene id: 1091494:MEALZ_RS11930
uniprot id: G4SVR1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1091494:MEALZ RS17875
gene id: 1091494:MEALZ_RS17875
uniprot id: G4SXE0
names: Similarity
messages: Belongs to the MlaA family.

1091494:MEALZ RS02090
gene id: 1091494:MEALZ_RS02090
uniprot id: G4SYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS09130
gene id: 1091494:MEALZ_RS09130
uniprot id: G4T2A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1091494:MEALZ RS17150
gene id: 1091494:MEALZ_RS17150
uniprot id: G4SVS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1091494:MEALZ RS05915
gene id: 1091494:MEALZ_RS05915
uniprot id: G4SUS7
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS00085
gene id: 1091494:MEALZ_RS00085
uniprot id: G4STP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1091494:MEALZ RS09360
gene id: 1091494:MEALZ_RS09360
uniprot id: G4T2F3
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16260
gene id: 1091494:MEALZ_RS16260
uniprot id: G4STJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1091494:MEALZ RS09970
gene id: 1091494:MEALZ_RS09970
uniprot id: G4T3J3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1091494:MEALZ RS13020
gene id: 1091494:MEALZ_RS13020
uniprot id: G4SY40
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1091494:MEALZ RS02495
gene id: 1091494:MEALZ_RS02495
uniprot id: G4SZ54
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1091494:MEALZ RS08810
gene id: 1091494:MEALZ_RS08810
uniprot id: G4T1Q3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1091494:MEALZ RS01630
gene id: 1091494:MEALZ_RS01630
uniprot id: G4SWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1091494:MEALZ RS03405
gene id: 1091494:MEALZ_RS03405
uniprot id: G4T1H4
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1091494:MEALZ RS13890
gene id: 1091494:MEALZ_RS13890
uniprot id: G4T0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS07605
gene id: 1091494:MEALZ_RS07605
uniprot id: G4SZB0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS02690
gene id: 1091494:MEALZ_RS02690
uniprot id: G4SZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1091494:MEALZ RS07965
gene id: 1091494:MEALZ_RS07965
uniprot id: G4T031
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS12225
gene id: 1091494:MEALZ_RS12225
uniprot id: G4SWG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS06150
gene id: 1091494:MEALZ_RS06150
uniprot id: G4SVH9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1091494:MEALZ RS08835
gene id: 1091494:MEALZ_RS08835
uniprot id: G4T1Q8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1091494:MEALZ RS01350
gene id: 1091494:MEALZ_RS01350
uniprot id: G4SW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1091494:MEALZ RS13550
gene id: 1091494:MEALZ_RS13550
uniprot id: G4SZL1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1091494:MEALZ RS16320
gene id: 1091494:MEALZ_RS16320
uniprot id: G4STK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1091494:MEALZ RS07075
gene id: 1091494:MEALZ_RS07075
uniprot id: G4SXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1091494:MEALZ RS00650
gene id: 1091494:MEALZ_RS00650
uniprot id: G4SUJ9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1091494:MEALZ RS07790
gene id: 1091494:MEALZ_RS07790
uniprot id: G4SZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1091494:MEALZ RS16325
gene id: 1091494:MEALZ_RS16325
uniprot id: G4STK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1091494:MEALZ RS03575
gene id: 1091494:MEALZ_RS03575
uniprot id: G4T1L2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1091494:MEALZ RS03655
gene id: 1091494:MEALZ_RS03655
uniprot id: G4T225
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1091494:MEALZ RS05980
gene id: 1091494:MEALZ_RS05980
uniprot id: G4SVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1091494:MEALZ RS19955
gene id: 1091494:MEALZ_RS19955
uniprot id: G4T4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1091494:MEALZ RS09245
gene id: 1091494:MEALZ_RS09245
uniprot id: G4T2D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS07365
gene id: 1091494:MEALZ_RS07365
uniprot id: G4SYL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1091494:MEALZ RS03320
gene id: 1091494:MEALZ_RS03320
uniprot id: G4T0U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1091494:MEALZ RS12145
gene id: 1091494:MEALZ_RS12145
uniprot id: G4SWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1091494:MEALZ RS17385
gene id: 1091494:MEALZ_RS17385
uniprot id: G4SVW9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1091494:MEALZ RS06250
gene id: 1091494:MEALZ_RS06250
uniprot id: G4SVJ9
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS04145
gene id: 1091494:MEALZ_RS04145
uniprot id: G4T2S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1091494:MEALZ RS08670
gene id: 1091494:MEALZ_RS08670
uniprot id: G4T1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1091494:MEALZ RS00660
gene id: 1091494:MEALZ_RS00660
uniprot id: G4SUK1
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS14200
gene id: 1091494:MEALZ_RS14200
uniprot id: G4T150
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1091494:MEALZ RS11320
gene id: 1091494:MEALZ_RS11320
uniprot id: G4SUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1091494:MEALZ RS05720
gene id: 1091494:MEALZ_RS05720
uniprot id: G4SUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1091494:MEALZ RS16615
gene id: 1091494:MEALZ_RS16615
uniprot id: G4SUB0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1091494:MEALZ RS19045
gene id: 1091494:MEALZ_RS19045
uniprot id: G4SZT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1091494:MEALZ RS01980
gene id: 1091494:MEALZ_RS01980
uniprot id: G4SXP5
names: Similarity
messages: Belongs to the HSP15 family.

1091494:MEALZ RS13720
gene id: 1091494:MEALZ_RS13720
uniprot id: G4T099
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1091494:MEALZ RS11110
gene id: 1091494:MEALZ_RS11110
uniprot id: G4SU44
names: Similarity
messages: Belongs to the peptidase S8 family.

1091494:MEALZ RS16665
gene id: 1091494:MEALZ_RS16665
uniprot id: G4SUC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1091494:MEALZ RS05470
gene id: 1091494:MEALZ_RS05470
uniprot id: G4STZ1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1091494:MEALZ RS19020
gene id: 1091494:MEALZ_RS19020
uniprot id: G4SZT0
names: Similarity
messages: Belongs to the peptidase M1 family.

1091494:MEALZ RS03620
gene id: 1091494:MEALZ_RS03620
uniprot id: G4T1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1091494:MEALZ RS05745
gene id: 1091494:MEALZ_RS05745
uniprot id: G4SUP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1091494:MEALZ RS10890
gene id: 1091494:MEALZ_RS10890
uniprot id: G4STF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1091494:MEALZ RS00885
gene id: 1091494:MEALZ_RS00885
uniprot id: G4SV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1091494:MEALZ RS07135
gene id: 1091494:MEALZ_RS07135
uniprot id: G4SXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1091494:MEALZ RS09955
gene id: 1091494:MEALZ_RS09955
uniprot id: G4T3J0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1091494:MEALZ RS06570
gene id: 1091494:MEALZ_RS06570
uniprot id: G4SWC0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1091494:MEALZ RS06530
gene id: 1091494:MEALZ_RS06530
uniprot id: G4SWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS19055
gene id: 1091494:MEALZ_RS19055
uniprot id: G4SZT7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1091494:MEALZ RS16775
gene id: 1091494:MEALZ_RS16775
uniprot id: G4SUE2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1091494:MEALZ RS09275
gene id: 1091494:MEALZ_RS09275
uniprot id: G4T2D6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1091494:MEALZ RS02940
gene id: 1091494:MEALZ_RS02940
uniprot id: G4T010
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1091494:MEALZ RS19430
gene id: 1091494:MEALZ_RS19430
uniprot id: G4T0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1091494:MEALZ RS15740
gene id: 1091494:MEALZ_RS15740
uniprot id: G4T3T3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1091494:MEALZ RS07880
gene id: 1091494:MEALZ_RS07880
uniprot id: G4SZH6
names: Similarity
messages: Belongs to the type III secretion exporter family.

1091494:MEALZ RS11370
gene id: 1091494:MEALZ_RS11370
uniprot id: G4SUU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1091494:MEALZ RS15445
gene id: 1091494:MEALZ_RS15445
uniprot id: G4T3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1091494:MEALZ RS06380
gene id: 1091494:MEALZ_RS06380
uniprot id: G4SW82
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1091494:MEALZ RS02770
gene id: 1091494:MEALZ_RS02770
uniprot id: G4SZX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1091494:MEALZ RS09050
gene id: 1091494:MEALZ_RS09050
uniprot id: G4T292
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1091494:MEALZ RS19235
gene id: 1091494:MEALZ_RS19235
uniprot id: G4T0H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19290
gene id: 1091494:MEALZ_RS19290
uniprot id: G4T0I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS14405
gene id: 1091494:MEALZ_RS14405
uniprot id: G4T1U8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS08650
gene id: 1091494:MEALZ_RS08650
uniprot id: G4T117
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1091494:MEALZ RS19735
gene id: 1091494:MEALZ_RS19735
uniprot id: G4T1C5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS02895
gene id: 1091494:MEALZ_RS02895
uniprot id: G4SZZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS15095
gene id: 1091494:MEALZ_RS15095
uniprot id: G4T2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1091494:MEALZ RS07905
gene id: 1091494:MEALZ_RS07905
uniprot id: G4SZG9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1091494:MEALZ RS06360
gene id: 1091494:MEALZ_RS06360
uniprot id: G4SW78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1091494:MEALZ RS07920
gene id: 1091494:MEALZ_RS07920
uniprot id: G4SZH2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1091494:MEALZ RS06550
gene id: 1091494:MEALZ_RS06550
uniprot id: G4SWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1091494:MEALZ RS15285
gene id: 1091494:MEALZ_RS15285
uniprot id: G4T352
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1091494:MEALZ RS16255
gene id: 1091494:MEALZ_RS16255
uniprot id: G4STJ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1091494:MEALZ RS08870
gene id: 1091494:MEALZ_RS08870
uniprot id: G4T1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1091494:MEALZ RS05815
gene id: 1091494:MEALZ_RS05815
uniprot id: G4SUQ4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1091494:MEALZ RS14770
gene id: 1091494:MEALZ_RS14770
uniprot id: G4T2G2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1091494:MEALZ RS00450
gene id: 1091494:MEALZ_RS00450
uniprot id: G4SUG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1091494:MEALZ RS02820
gene id: 1091494:MEALZ_RS02820
uniprot id: G4SZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1091494:MEALZ RS09330
gene id: 1091494:MEALZ_RS09330
uniprot id: G4T2E7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1091494:MEALZ RS11155
gene id: 1091494:MEALZ_RS11155
uniprot id: G4SU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1091494:MEALZ RS18925
gene id: 1091494:MEALZ_RS18925
uniprot id: G4SZR4
names: Similarity
messages: Belongs to the UPF0175 family.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS14300
gene id: 1091494:MEALZ_RS14300
uniprot id: G4T170
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1091494:MEALZ RS16085
gene id: 1091494:MEALZ_RS16085
uniprot id: G4T4F0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1091494:MEALZ RS17880
gene id: 1091494:MEALZ_RS17880
uniprot id: G4SXE1
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS06705
gene id: 1091494:MEALZ_RS06705
uniprot id: G4SX07
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1091494:MEALZ RS15150
gene id: 1091494:MEALZ_RS15150
uniprot id: G4T323
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS18175
gene id: 1091494:MEALZ_RS18175
uniprot id: G4SY53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1091494:MEALZ RS15105
gene id: 1091494:MEALZ_RS15105
uniprot id: G4T2M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1091494:MEALZ RS06400
gene id: 1091494:MEALZ_RS06400
uniprot id: G4SW86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cell inner membrane
messages: Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast.

1091494:MEALZ RS04040
gene id: 1091494:MEALZ_RS04040
uniprot id: G4T2P5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1091494:MEALZ RS11800
gene id: 1091494:MEALZ_RS11800
uniprot id: G4SVN4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1091494:MEALZ RS11350
gene id: 1091494:MEALZ_RS11350
uniprot id: G4SUT8
names: Similarity
messages: Belongs to the hemerythrin family.

1091494:MEALZ RS03090
gene id: 1091494:MEALZ_RS03090
uniprot id: G4T0Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1091494:MEALZ RS19730
gene id: 1091494:MEALZ_RS19730
uniprot id: G4T1C4
names: Similarity
messages: Belongs to the peptidase C15 family.

1091494:MEALZ RS05475
gene id: 1091494:MEALZ_RS05475
uniprot id: G4STZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1091494:MEALZ RS06465
gene id: 1091494:MEALZ_RS06465
uniprot id: G4SWA0
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS03950
gene id: 1091494:MEALZ_RS03950
uniprot id: G4T285
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS11240
gene id: 1091494:MEALZ_RS11240
uniprot id: G4SU71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1091494:MEALZ RS12610
gene id: 1091494:MEALZ_RS12610
uniprot id: G4SX99
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1091494:MEALZ RS04350
gene id: 1091494:MEALZ_RS04350
uniprot id: G4T3A2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1091494:MEALZ RS15775
gene id: 1091494:MEALZ_RS15775
uniprot id: G4T486
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS08695
gene id: 1091494:MEALZ_RS08695
uniprot id: G4T1N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1091494:MEALZ RS02660
gene id: 1091494:MEALZ_RS02660
uniprot id: G4SZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1091494:MEALZ RS03660
gene id: 1091494:MEALZ_RS03660
uniprot id: G4T226
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1091494:MEALZ RS13830
gene id: 1091494:MEALZ_RS13830
uniprot id: G4T0B8
names: Similarity
messages: Belongs to the aspartokinase family.

1091494:MEALZ RS12435
gene id: 1091494:MEALZ_RS12435
uniprot id: G4SX60
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1091494:MEALZ RS17285
gene id: 1091494:MEALZ_RS17285
uniprot id: G4SVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1091494:MEALZ RS05070
gene id: 1091494:MEALZ_RS05070
uniprot id: G4ST23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1091494:MEALZ RS16435
gene id: 1091494:MEALZ_RS16435
uniprot id: G4STM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS04515
gene id: 1091494:MEALZ_RS04515
uniprot id: G4T3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1091494:MEALZ RS07420
gene id: 1091494:MEALZ_RS07420
uniprot id: G4SYM3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1091494:MEALZ RS19435
gene id: 1091494:MEALZ_RS19435
uniprot id: G4T0L3
names: Similarity
messages: Belongs to the thioredoxin family.

1091494:MEALZ RS10960
gene id: 1091494:MEALZ_RS10960
uniprot id: G4STG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1091494:MEALZ RS05605
gene id: 1091494:MEALZ_RS05605
uniprot id: G4SU15
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1091494:MEALZ RS11175
gene id: 1091494:MEALZ_RS11175
uniprot id: G4SU58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS15145
gene id: 1091494:MEALZ_RS15145
uniprot id: G4T322
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09025
gene id: 1091494:MEALZ_RS09025
uniprot id: G4T287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1091494:MEALZ RS12930
gene id: 1091494:MEALZ_RS12930
uniprot id: G4SY22
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1091494:MEALZ RS10555
gene id: 1091494:MEALZ_RS10555
uniprot id: G4ST90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1091494:MEALZ RS03870
gene id: 1091494:MEALZ_RS03870
uniprot id: G4T270
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1091494:MEALZ RS13905
gene id: 1091494:MEALZ_RS13905
uniprot id: G4T0D3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS05465
gene id: 1091494:MEALZ_RS05465
uniprot id: G4STZ0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1091494:MEALZ RS16540
gene id: 1091494:MEALZ_RS16540
uniprot id: G4SU96
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1091494:MEALZ RS16405
gene id: 1091494:MEALZ_RS16405
uniprot id: G4STM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1091494:MEALZ RS08370
gene id: 1091494:MEALZ_RS08370
uniprot id: G4T0X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1091494:MEALZ RS18035
gene id: 1091494:MEALZ_RS18035
uniprot id: G4SXH1
names: Similarity
messages: Belongs to the HsdR family.

1091494:MEALZ RS04495
gene id: 1091494:MEALZ_RS04495
uniprot id: G4T3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1091494:MEALZ RS09205
gene id: 1091494:MEALZ_RS09205
uniprot id: G4T2C3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1091494:MEALZ RS11040
gene id: 1091494:MEALZ_RS11040
uniprot id: G4SU28
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1091494:MEALZ RS01660
gene id: 1091494:MEALZ_RS01660
uniprot id: G4SWX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1091494:MEALZ RS07165
gene id: 1091494:MEALZ_RS07165
uniprot id: G4SXW1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS08100
gene id: 1091494:MEALZ_RS08100
uniprot id: G4T059
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1091494:MEALZ RS09800
gene id: 1091494:MEALZ_RS09800
uniprot id: G4T3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1091494:MEALZ RS16210
gene id: 1091494:MEALZ_RS16210
uniprot id: G4STI5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1091494:MEALZ RS12265
gene id: 1091494:MEALZ_RS12265
uniprot id: G4SWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1091494:MEALZ RS13930
gene id: 1091494:MEALZ_RS13930
uniprot id: G4T0D8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS04405
gene id: 1091494:MEALZ_RS04405
uniprot id: G4T3B2
names: Subcellular Location Annotation
messages: Cytoplasm

1091494:MEALZ RS06255
gene id: 1091494:MEALZ_RS06255
uniprot id: G4SVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1091494:MEALZ RS19050
gene id: 1091494:MEALZ_RS19050
uniprot id: G4SZT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1091494:MEALZ RS05930
gene id: 1091494:MEALZ_RS05930
uniprot id: G4SVD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1091494:MEALZ RS17665
gene id: 1091494:MEALZ_RS17665
uniprot id: G4SWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1091494:MEALZ RS02110
gene id: 1091494:MEALZ_RS02110
uniprot id: G4SYC7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1091494:MEALZ RS15215
gene id: 1091494:MEALZ_RS15215
uniprot id: G4T337
names: Similarity
messages: Belongs to the peptidase S49 family.

1091494:MEALZ RS09055
gene id: 1091494:MEALZ_RS09055
uniprot id: G4T293
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1091494:MEALZ RS09560
gene id: 1091494:MEALZ_RS09560
uniprot id: G4T2X7
names: Similarity
messages: Belongs to the VgrG protein family.

1091494:MEALZ RS16525
gene id: 1091494:MEALZ_RS16525
uniprot id: G4SU93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1091494:MEALZ RS17670
gene id: 1091494:MEALZ_RS17670
uniprot id: G4SWN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS11010
gene id: 1091494:MEALZ_RS11010
uniprot id: G4SU22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS03945
gene id: 1091494:MEALZ_RS03945
uniprot id: G4T284
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1091494:MEALZ RS02065
gene id: 1091494:MEALZ_RS02065
uniprot id: G4SXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS07215
gene id: 1091494:MEALZ_RS07215
uniprot id: G4SXX1
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16945
gene id: 1091494:MEALZ_RS16945
uniprot id: G4SV26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1091494:MEALZ RS18300
gene id: 1091494:MEALZ_RS18300
uniprot id: G4SY78
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00520
gene id: 1091494:MEALZ_RS00520
uniprot id: G4SUI0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1091494:MEALZ RS19670
gene id: 1091494:MEALZ_RS19670
uniprot id: G4T1B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS11885
gene id: 1091494:MEALZ_RS11885
uniprot id: G4SVQ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1091494:MEALZ RS01900
gene id: 1091494:MEALZ_RS01900
uniprot id: G4SXN0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1091494:MEALZ RS08915
gene id: 1091494:MEALZ_RS08915
uniprot id: G4T1S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1091494:MEALZ RS08020
gene id: 1091494:MEALZ_RS08020
uniprot id: G4T042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1091494:MEALZ RS09200
gene id: 1091494:MEALZ_RS09200
uniprot id: G4T2C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS16345
gene id: 1091494:MEALZ_RS16345
uniprot id: G4STL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1091494:MEALZ RS04965
gene id: 1091494:MEALZ_RS04965
uniprot id: G4ST03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1091494:MEALZ RS12230
gene id: 1091494:MEALZ_RS12230
uniprot id: G4SWG5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1091494:MEALZ RS10560
gene id: 1091494:MEALZ_RS10560
uniprot id: G4ST91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1091494:MEALZ RS06035
gene id: 1091494:MEALZ_RS06035
uniprot id: G4SVF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1091494:MEALZ RS12060
gene id: 1091494:MEALZ_RS12060
uniprot id: G4SWD3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1091494:MEALZ RS07070
gene id: 1091494:MEALZ_RS07070
uniprot id: G4SXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS08665
gene id: 1091494:MEALZ_RS08665
uniprot id: G4T1M6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1091494:MEALZ RS15475
gene id: 1091494:MEALZ_RS15475
uniprot id: G4T3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1091494:MEALZ RS05955
gene id: 1091494:MEALZ_RS05955
uniprot id: G4SVD9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1091494:MEALZ RS13760
gene id: 1091494:MEALZ_RS13760
uniprot id: G4T0A7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1091494:MEALZ RS17930
gene id: 1091494:MEALZ_RS17930
uniprot id: G4SXF1
names: Similarity
messages: Belongs to the UPF0178 family.

1091494:MEALZ RS03135
gene id: 1091494:MEALZ_RS03135
uniprot id: G4T0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1091494:MEALZ RS11515
gene id: 1091494:MEALZ_RS11515
uniprot id: G4SUX0
names: Similarity
messages: Belongs to the YoeB family.

1091494:MEALZ RS16580
gene id: 1091494:MEALZ_RS16580
uniprot id: G4SUA3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1091494:MEALZ RS03240
gene id: 1091494:MEALZ_RS03240
uniprot id: G4T0T1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1091494:MEALZ RS16870
gene id: 1091494:MEALZ_RS16870
uniprot id: G4SV11
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1091494:MEALZ RS10940
gene id: 1091494:MEALZ_RS10940
uniprot id: G4STF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1091494:MEALZ RS10935
gene id: 1091494:MEALZ_RS10935
uniprot id: G4STF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1091494:MEALZ RS10945
gene id: 1091494:MEALZ_RS10945
uniprot id: G4STF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1091494:MEALZ RS08085
gene id: 1091494:MEALZ_RS08085
uniprot id: G4T056
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1091494:MEALZ RS20660
gene id: 1091494:MEALZ_RS20660
uniprot id: G4SX32
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1091494:MEALZ RS14140
gene id: 1091494:MEALZ_RS14140
uniprot id: G4T138
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1091494:MEALZ RS05085
gene id: 1091494:MEALZ_RS05085
uniprot id: G4ST26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1091494:MEALZ RS05480
gene id: 1091494:MEALZ_RS05480
uniprot id: G4STZ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1091494:MEALZ RS19315
gene id: 1091494:MEALZ_RS19315
uniprot id: G4T0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS04890
gene id: 1091494:MEALZ_RS04890
uniprot id: G4T3Z8
names: Similarity
messages: Belongs to the acylphosphatase family.

1091494:MEALZ RS18270
gene id: 1091494:MEALZ_RS18270
uniprot id: G4SY72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1091494:MEALZ RS13510
gene id: 1091494:MEALZ_RS13510
uniprot id: G4SZK4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1091494:MEALZ RS12460
gene id: 1091494:MEALZ_RS12460
uniprot id: G4SX65
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1091494:MEALZ RS15225
gene id: 1091494:MEALZ_RS15225
uniprot id: G4T339
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1091494:MEALZ RS12205
gene id: 1091494:MEALZ_RS12205
uniprot id: G4SWG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS04445
gene id: 1091494:MEALZ_RS04445
uniprot id: G4T3B9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

1091494:MEALZ RS04550
gene id: 1091494:MEALZ_RS04550
uniprot id: G4T3E0
names: Similarity
messages: Belongs to the cytochrome c family. PetJ subfamily.

1091494:MEALZ RS19960
gene id: 1091494:MEALZ_RS19960
uniprot id: G4T4G1
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14790
gene id: 1091494:MEALZ_RS14790
uniprot id: G4T2G6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1091494:MEALZ RS02105
gene id: 1091494:MEALZ_RS02105
uniprot id: G4SYC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS13225
gene id: 1091494:MEALZ_RS13225
uniprot id: G4SYU0
names: Similarity
messages: Belongs to the transposase 8 family.

1091494:MEALZ RS02600
gene id: 1091494:MEALZ_RS02600
uniprot id: G4SZ78
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1091494:MEALZ RS16285
gene id: 1091494:MEALZ_RS16285
uniprot id: G4STK1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1091494:MEALZ RS02710
gene id: 1091494:MEALZ_RS02710
uniprot id: G4SZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS07960
gene id: 1091494:MEALZ_RS07960
uniprot id: G4T030
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1091494:MEALZ RS06605
gene id: 1091494:MEALZ_RS06605
uniprot id: G4SWY7
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS13535
gene id: 1091494:MEALZ_RS13535
uniprot id: G4SZK9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1091494:MEALZ RS17105
gene id: 1091494:MEALZ_RS17105
uniprot id: G4SV57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS15385
gene id: 1091494:MEALZ_RS15385
uniprot id: G4T385
names: Similarity
messages: Belongs to the MotB family.

1091494:MEALZ RS11285
gene id: 1091494:MEALZ_RS11285
uniprot id: G4SU79
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1091494:MEALZ RS03745
gene id: 1091494:MEALZ_RS03745
uniprot id: G4T244
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1091494:MEALZ RS04850
gene id: 1091494:MEALZ_RS04850
uniprot id: G4T3Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1091494:MEALZ RS11295
gene id: 1091494:MEALZ_RS11295
uniprot id: G4SU81
names: Similarity
messages: Belongs to the GARS family.

1091494:MEALZ RS03085
gene id: 1091494:MEALZ_RS03085
uniprot id: G4T0Q0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1091494:MEALZ RS04960
gene id: 1091494:MEALZ_RS04960
uniprot id: G4ST02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1091494:MEALZ RS19340
gene id: 1091494:MEALZ_RS19340
uniprot id: G4T0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1091494:MEALZ RS00435
gene id: 1091494:MEALZ_RS00435
uniprot id: G4SUG4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1091494:MEALZ RS05005
gene id: 1091494:MEALZ_RS05005
uniprot id: G4ST11
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS09090
gene id: 1091494:MEALZ_RS09090
uniprot id: G4T2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS14940
gene id: 1091494:MEALZ_RS14940
uniprot id: G4T2J4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS12280
gene id: 1091494:MEALZ_RS12280
uniprot id: G4SWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1091494:MEALZ RS17080
gene id: 1091494:MEALZ_RS17080
uniprot id: G4SV54
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14680
gene id: 1091494:MEALZ_RS14680
uniprot id: G4T201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1091494:MEALZ RS02985
gene id: 1091494:MEALZ_RS02985
uniprot id: G4T021
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

1091494:MEALZ RS09965
gene id: 1091494:MEALZ_RS09965
uniprot id: G4T3J2
names: Similarity
messages: Belongs to the fabD family.

1091494:MEALZ RS08315
gene id: 1091494:MEALZ_RS08315
uniprot id: G4T0V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1091494:MEALZ RS19140
gene id: 1091494:MEALZ_RS19140
uniprot id: G4SZV3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1091494:MEALZ RS08305
gene id: 1091494:MEALZ_RS08305
uniprot id: G4T0V7
names: Similarity
messages: Belongs to the histone deacetylase family.

1091494:MEALZ RS06900
gene id: 1091494:MEALZ_RS06900
uniprot id: G4SX47
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS11335
gene id: 1091494:MEALZ_RS11335
uniprot id: G4SUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1091494:MEALZ RS14490
gene id: 1091494:MEALZ_RS14490
uniprot id: G4T1W5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1091494:MEALZ RS10475
gene id: 1091494:MEALZ_RS10475
uniprot id: G4ST73
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1091494:MEALZ RS14420
gene id: 1091494:MEALZ_RS14420
uniprot id: G4T1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1091494:MEALZ RS00040
gene id: 1091494:MEALZ_RS00040
uniprot id: G4STN9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1091494:MEALZ RS13880
gene id: 1091494:MEALZ_RS13880
uniprot id: G4T0C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1091494:MEALZ RS16680
gene id: 1091494:MEALZ_RS16680
uniprot id: G4SUC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1091494:MEALZ RS13945
gene id: 1091494:MEALZ_RS13945
uniprot id: G4T0E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1091494:MEALZ RS03970
gene id: 1091494:MEALZ_RS03970
uniprot id: G4T2N1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1091494:MEALZ RS03075
gene id: 1091494:MEALZ_RS03075
uniprot id: G4T0P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1091494:MEALZ RS16990
gene id: 1091494:MEALZ_RS16990
uniprot id: G4SV35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS09875
gene id: 1091494:MEALZ_RS09875
uniprot id: G4T3H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS07675
gene id: 1091494:MEALZ_RS07675
uniprot id: G4SZC3
names: Similarity
messages: Belongs to the IMPACT family.

1091494:MEALZ RS09840
gene id: 1091494:MEALZ_RS09840
uniprot id: G4T3G6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1091494:MEALZ RS19305
gene id: 1091494:MEALZ_RS19305
uniprot id: G4T0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS16920
gene id: 1091494:MEALZ_RS16920
uniprot id: G4SV21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1091494:MEALZ RS16755
gene id: 1091494:MEALZ_RS16755
uniprot id: G4SUD8
names: Similarity
messages: Belongs to the Smg family.

1091494:MEALZ RS00705
gene id: 1091494:MEALZ_RS00705
uniprot id: G4SUL0
names: Similarity
messages: Belongs to the YggT family.

1091494:MEALZ RS00475
gene id: 1091494:MEALZ_RS00475
uniprot id: G4SUH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS04530
gene id: 1091494:MEALZ_RS04530
uniprot id: G4T3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1091494:MEALZ RS05230
gene id: 1091494:MEALZ_RS05230
uniprot id: G4ST55
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1091494:MEALZ RS00015
gene id: 1091494:MEALZ_RS00015
uniprot id: G4STN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1091494:MEALZ RS14960
gene id: 1091494:MEALZ_RS14960
uniprot id: G4T2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1091494:MEALZ RS09695
gene id: 1091494:MEALZ_RS09695
uniprot id: G4T305
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1091494:MEALZ RS17315
gene id: 1091494:MEALZ_RS17315
uniprot id: G4SVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1091494:MEALZ RS07895
gene id: 1091494:MEALZ_RS07895
uniprot id: G4SZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1091494:MEALZ RS11290
gene id: 1091494:MEALZ_RS11290
uniprot id: G4SU80
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1091494:MEALZ RS08415
gene id: 1091494:MEALZ_RS08415
uniprot id: G4T0X9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1091494:MEALZ RS15360
gene id: 1091494:MEALZ_RS15360
uniprot id: G4T370
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1091494:MEALZ RS11310
gene id: 1091494:MEALZ_RS11310
uniprot id: G4SUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1091494:MEALZ RS00210
gene id: 1091494:MEALZ_RS00210
uniprot id: G4STS3
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS13735
gene id: 1091494:MEALZ_RS13735
uniprot id: G4T0A2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1091494:MEALZ RS08110
gene id: 1091494:MEALZ_RS08110
uniprot id: G4T061
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1091494:MEALZ RS08660
gene id: 1091494:MEALZ_RS08660
uniprot id: G4T1M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1091494:MEALZ RS16585
gene id: 1091494:MEALZ_RS16585
uniprot id: G4SUA4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS16590
gene id: 1091494:MEALZ_RS16590
uniprot id: G4SUA5
names: Similarity
messages: Belongs to the UPF0250 family.

1091494:MEALZ RS17565
gene id: 1091494:MEALZ_RS17565
uniprot id: G4SWL6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1091494:MEALZ RS02705
gene id: 1091494:MEALZ_RS02705
uniprot id: G4SZA1
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS06640
gene id: 1091494:MEALZ_RS06640
uniprot id: G4SWZ4
names: Similarity
messages: Belongs to the citrate synthase family.

1091494:MEALZ RS04050
gene id: 1091494:MEALZ_RS04050
uniprot id: G4T2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1091494:MEALZ RS02595
gene id: 1091494:MEALZ_RS02595
uniprot id: G4SZ76
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17645
gene id: 1091494:MEALZ_RS17645
uniprot id: G4SWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1091494:MEALZ RS13780
gene id: 1091494:MEALZ_RS13780
uniprot id: G4T0B1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1091494:MEALZ RS16080
gene id: 1091494:MEALZ_RS16080
uniprot id: G4T4E9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1091494:MEALZ RS16295
gene id: 1091494:MEALZ_RS16295
uniprot id: G4STK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1091494:MEALZ RS09300
gene id: 1091494:MEALZ_RS09300
uniprot id: G4T2E1
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1091494:MEALZ RS15875
gene id: 1091494:MEALZ_RS15875
uniprot id: G4T4A6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS08940
gene id: 1091494:MEALZ_RS08940
uniprot id: G4T1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1091494:MEALZ RS13430
gene id: 1091494:MEALZ_RS13430
uniprot id: G4SZI8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1091494:MEALZ RS14735
gene id: 1091494:MEALZ_RS14735
uniprot id: G4T210
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1091494:MEALZ RS02570
gene id: 1091494:MEALZ_RS02570
uniprot id: G4SZ71
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1091494:MEALZ RS05585
gene id: 1091494:MEALZ_RS05585
uniprot id: G4SU11
names: Similarity
messages: Belongs to the LOG family.

1091494:MEALZ RS11200
gene id: 1091494:MEALZ_RS11200
uniprot id: G4SU63
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1091494:MEALZ RS17225
gene id: 1091494:MEALZ_RS17225
uniprot id: G4SVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1091494:MEALZ RS16420
gene id: 1091494:MEALZ_RS16420
uniprot id: G4STN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1091494:MEALZ RS07795
gene id: 1091494:MEALZ_RS07795
uniprot id: G4SZF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1091494:MEALZ RS04665
gene id: 1091494:MEALZ_RS04665
uniprot id: G4T3V5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1091494:MEALZ RS01935
gene id: 1091494:MEALZ_RS01935
uniprot id: G4SXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1091494:MEALZ RS17840
gene id: 1091494:MEALZ_RS17840
uniprot id: G4SXD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1091494:MEALZ RS12095
gene id: 1091494:MEALZ_RS12095
uniprot id: G4SWE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1091494:MEALZ RS07345
gene id: 1091494:MEALZ_RS07345
uniprot id: G4SYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1091494:MEALZ RS17115
gene id: 1091494:MEALZ_RS17115
uniprot id: G4SV59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1091494:MEALZ RS02910
gene id: 1091494:MEALZ_RS02910
uniprot id: G4T003
names: Subunit
messages: Monomer. Interacts with PqqE.

1091494:MEALZ RS07565
gene id: 1091494:MEALZ_RS07565
uniprot id: G4SYQ3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1091494:MEALZ RS06015
gene id: 1091494:MEALZ_RS06015
uniprot id: G4SVF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1091494:MEALZ RS04985
gene id: 1091494:MEALZ_RS04985
uniprot id: G4ST07
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS13200
gene id: 1091494:MEALZ_RS13200
uniprot id: G4SYT5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1091494:MEALZ RS16275
gene id: 1091494:MEALZ_RS16275
uniprot id: G4STJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1091494:MEALZ RS11475
gene id: 1091494:MEALZ_RS11475
uniprot id: G4SUW1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1091494:MEALZ RS08910
gene id: 1091494:MEALZ_RS08910
uniprot id: G4T1S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS15945
gene id: 1091494:MEALZ_RS15945
uniprot id: G4T4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS01665
gene id: 1091494:MEALZ_RS01665
uniprot id: G4SWX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS10065
gene id: 1091494:MEALZ_RS10065
uniprot id: G4T3M0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1091494:MEALZ RS11490
gene id: 1091494:MEALZ_RS11490
uniprot id: G4SUW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1091494:MEALZ RS15315
gene id: 1091494:MEALZ_RS15315
uniprot id: G4T359
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1091494:MEALZ RS12790
gene id: 1091494:MEALZ_RS12790
uniprot id: G4SXZ4
names: Similarity
messages: Belongs to the oxoprolinase family.

1091494:MEALZ RS04840
gene id: 1091494:MEALZ_RS04840
uniprot id: G4T3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1091494:MEALZ RS03650
gene id: 1091494:MEALZ_RS03650
uniprot id: G4T224
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1091494:MEALZ RS05960
gene id: 1091494:MEALZ_RS05960
uniprot id: G4SVE0
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS00800
gene id: 1091494:MEALZ_RS00800
uniprot id: G4SV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1091494:MEALZ RS01920
gene id: 1091494:MEALZ_RS01920
uniprot id: G4SXN4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1091494:MEALZ RS19535
gene id: 1091494:MEALZ_RS19535
uniprot id: G4T0N1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS01525
gene id: 1091494:MEALZ_RS01525
uniprot id: G4SWU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1091494:MEALZ RS01700
gene id: 1091494:MEALZ_RS01700
uniprot id: G4SWY0
names: Similarity
messages: Belongs to the HsdR family.

1091494:MEALZ RS11670
gene id: 1091494:MEALZ_RS11670
uniprot id: G4SVK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1091494:MEALZ RS06455
gene id: 1091494:MEALZ_RS06455
uniprot id: G4SW98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS07205
gene id: 1091494:MEALZ_RS07205
uniprot id: G4SXW9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1091494:MEALZ RS20275
gene id: 1091494:MEALZ_RS20275
uniprot id: G4T4M0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1091494:MEALZ RS16390
gene id: 1091494:MEALZ_RS16390
uniprot id: G4STM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1091494:MEALZ RS00710
gene id: 1091494:MEALZ_RS00710
uniprot id: G4SUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1091494:MEALZ RS16415
gene id: 1091494:MEALZ_RS16415
uniprot id: G4STN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1091494:MEALZ RS17585
gene id: 1091494:MEALZ_RS17585
uniprot id: G4SWM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1091494:MEALZ RS15230
gene id: 1091494:MEALZ_RS15230
uniprot id: G4T340
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1091494:MEALZ RS13045
gene id: 1091494:MEALZ_RS13045
uniprot id: G4SY49
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1091494:MEALZ RS12990
gene id: 1091494:MEALZ_RS12990
uniprot id: G4SY34
names: Similarity
messages: Belongs to the peptidase M18 family.

1091494:MEALZ RS07585
gene id: 1091494:MEALZ_RS07585
uniprot id: G4SZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1091494:MEALZ RS06500
gene id: 1091494:MEALZ_RS06500
uniprot id: G4SWA7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS04155
gene id: 1091494:MEALZ_RS04155
uniprot id: G4T2S2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1091494:MEALZ RS06210
gene id: 1091494:MEALZ_RS06210
uniprot id: G4SVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1091494:MEALZ RS00365
gene id: 1091494:MEALZ_RS00365
uniprot id: G4SUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS17680
gene id: 1091494:MEALZ_RS17680
uniprot id: G4SWN8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS13420
gene id: 1091494:MEALZ_RS13420
uniprot id: G4SZI6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1091494:MEALZ RS16060
gene id: 1091494:MEALZ_RS16060
uniprot id: G4T4E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1091494:MEALZ RS14280
gene id: 1091494:MEALZ_RS14280
uniprot id: G4T166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1091494:MEALZ RS07315
gene id: 1091494:MEALZ_RS07315
uniprot id: G4SYK0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1091494:MEALZ RS17410
gene id: 1091494:MEALZ_RS17410
uniprot id: G4SVX4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1091494:MEALZ RS08055
gene id: 1091494:MEALZ_RS08055
uniprot id: G4T050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1091494:MEALZ RS13085
gene id: 1091494:MEALZ_RS13085
uniprot id: G4SYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS18760
gene id: 1091494:MEALZ_RS18760
uniprot id: G4SZ25
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1091494:MEALZ RS16550
gene id: 1091494:MEALZ_RS16550
uniprot id: G4SU97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1091494:MEALZ RS23270
gene id: 1091494:MEALZ_RS23270
uniprot id: G4SUK7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1091494:MEALZ RS06330
gene id: 1091494:MEALZ_RS06330
uniprot id: G4SW72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1091494:MEALZ RS18345
gene id: 1091494:MEALZ_RS18345
uniprot id: G4SY87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1091494:MEALZ RS05260
gene id: 1091494:MEALZ_RS05260
uniprot id: G4ST60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1091494:MEALZ RS16380
gene id: 1091494:MEALZ_RS16380
uniprot id: G4STM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1091494:MEALZ RS01520
gene id: 1091494:MEALZ_RS01520
uniprot id: G4SWU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1091494:MEALZ RS07275
gene id: 1091494:MEALZ_RS07275
uniprot id: G4SYJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1091494:MEALZ RS06875
gene id: 1091494:MEALZ_RS06875
uniprot id: G4SX42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1091494:MEALZ RS09690
gene id: 1091494:MEALZ_RS09690
uniprot id: G4T304
names: Similarity
messages: Belongs to the HypD family.

1091494:MEALZ RS07225
gene id: 1091494:MEALZ_RS07225
uniprot id: G4SXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1091494:MEALZ RS03280
gene id: 1091494:MEALZ_RS03280
uniprot id: G4T0U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1091494:MEALZ RS20475
gene id: 1091494:MEALZ_RS20475
uniprot id: G4T4R3
names: Similarity
messages: Belongs to the XFP family.

1091494:MEALZ RS14220
gene id: 1091494:MEALZ_RS14220
uniprot id: G4T154
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1091494:MEALZ RS04535
gene id: 1091494:MEALZ_RS04535
uniprot id: G4T3D7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1091494:MEALZ RS11645
gene id: 1091494:MEALZ_RS11645
uniprot id: G4SV00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1091494:MEALZ RS01690
gene id: 1091494:MEALZ_RS01690
uniprot id: G4SWX8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1091494:MEALZ RS14445
gene id: 1091494:MEALZ_RS14445
uniprot id: G4T1V6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1091494:MEALZ RS17290
gene id: 1091494:MEALZ_RS17290
uniprot id: G4SVV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1091494:MEALZ RS04585
gene id: 1091494:MEALZ_RS04585
uniprot id: G4T3U0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1091494:MEALZ RS16505
gene id: 1091494:MEALZ_RS16505
uniprot id: G4SU89
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1091494:MEALZ RS03155
gene id: 1091494:MEALZ_RS03155
uniprot id: G4T0R4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1091494:MEALZ RS17335
gene id: 1091494:MEALZ_RS17335
uniprot id: G4SVW5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1091494:MEALZ RS03485
gene id: 1091494:MEALZ_RS03485
uniprot id: G4T1J2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1091494:MEALZ RS03330
gene id: 1091494:MEALZ_RS03330
uniprot id: G4T1F9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1091494:MEALZ RS07240
gene id: 1091494:MEALZ_RS07240
uniprot id: G4SXX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1091494:MEALZ RS02640
gene id: 1091494:MEALZ_RS02640
uniprot id: G4SZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS18090
gene id: 1091494:MEALZ_RS18090
uniprot id: G4SXI2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1091494:MEALZ RS03985
gene id: 1091494:MEALZ_RS03985
uniprot id: G4T2N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS13525
gene id: 1091494:MEALZ_RS13525
uniprot id: G4SZK7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1091494:MEALZ RS04355
gene id: 1091494:MEALZ_RS04355
uniprot id: G4T3A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1091494:MEALZ RS00370
gene id: 1091494:MEALZ_RS00370
uniprot id: G4SUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1091494:MEALZ RS04140
gene id: 1091494:MEALZ_RS04140
uniprot id: G4T2R9
names: Similarity
messages: Belongs to the P(II) protein family.

1091494:MEALZ RS09985
gene id: 1091494:MEALZ_RS09985
uniprot id: G4T3J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1091494:MEALZ RS16780
gene id: 1091494:MEALZ_RS16780
uniprot id: G4SUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1091494:MEALZ RS02020
gene id: 1091494:MEALZ_RS02020
uniprot id: G4SXQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS16375
gene id: 1091494:MEALZ_RS16375
uniprot id: G4STL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1091494:MEALZ RS15545
gene id: 1091494:MEALZ_RS15545
uniprot id: G4T3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS12515
gene id: 1091494:MEALZ_RS12515
uniprot id: G4SX76
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS04805
gene id: 1091494:MEALZ_RS04805
uniprot id: G4T3Y1
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1091494:MEALZ RS13090
gene id: 1091494:MEALZ_RS13090
uniprot id: G4SYQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1091494:MEALZ RS14740
gene id: 1091494:MEALZ_RS14740
uniprot id: G4T211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1091494:MEALZ RS17170
gene id: 1091494:MEALZ_RS17170
uniprot id: G4SVT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1091494:MEALZ RS20050
gene id: 1091494:MEALZ_RS20050
uniprot id: G4T4H9
names: Similarity
messages: Belongs to the ParB family.

1091494:MEALZ RS19155
gene id: 1091494:MEALZ_RS19155
uniprot id: G4SZV6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS05935
gene id: 1091494:MEALZ_RS05935
uniprot id: G4SVD6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1091494:MEALZ RS07620
gene id: 1091494:MEALZ_RS07620
uniprot id: G4SZB3
names: Similarity
messages: Belongs to the RecJ family.

1091494:MEALZ RS18740
gene id: 1091494:MEALZ_RS18740
uniprot id: G4SZ21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1091494:MEALZ RS08805
gene id: 1091494:MEALZ_RS08805
uniprot id: G4T1Q2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1091494:MEALZ RS03680
gene id: 1091494:MEALZ_RS03680
uniprot id: G4T230
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1091494:MEALZ RS01380
gene id: 1091494:MEALZ_RS01380
uniprot id: G4SWR5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1091494:MEALZ RS00465
gene id: 1091494:MEALZ_RS00465
uniprot id: G4SUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1091494:MEALZ RS16500
gene id: 1091494:MEALZ_RS16500
uniprot id: G4SU88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1091494:MEALZ RS03670
gene id: 1091494:MEALZ_RS03670
uniprot id: G4T228
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1091494:MEALZ RS06045
gene id: 1091494:MEALZ_RS06045
uniprot id: G4SVF7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS15500
gene id: 1091494:MEALZ_RS15500
uniprot id: G4T3N4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS04895
gene id: 1091494:MEALZ_RS04895
uniprot id: G4T3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1091494:MEALZ RS17435
gene id: 1091494:MEALZ_RS17435
uniprot id: G4SVX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS17705
gene id: 1091494:MEALZ_RS17705
uniprot id: G4SWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1091494:MEALZ RS14195
gene id: 1091494:MEALZ_RS14195
uniprot id: G4T149
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1091494:MEALZ RS06730
gene id: 1091494:MEALZ_RS06730
uniprot id: G4SX12
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1091494:MEALZ RS14275
gene id: 1091494:MEALZ_RS14275
uniprot id: G4T165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS01635
gene id: 1091494:MEALZ_RS01635
uniprot id: G4SWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1091494:MEALZ RS08700
gene id: 1091494:MEALZ_RS08700
uniprot id: G4T1N3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1091494:MEALZ RS01285
gene id: 1091494:MEALZ_RS01285
uniprot id: G4SW41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1091494:MEALZ RS03175
gene id: 1091494:MEALZ_RS03175
uniprot id: G4T0R8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1091494:MEALZ RS17650
gene id: 1091494:MEALZ_RS17650
uniprot id: G4SWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1091494:MEALZ RS19630
gene id: 1091494:MEALZ_RS19630
uniprot id: G4T1A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1091494:MEALZ RS16125
gene id: 1091494:MEALZ_RS16125
uniprot id: G4STH1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1091494:MEALZ RS14150
gene id: 1091494:MEALZ_RS14150
uniprot id: G4T140
names: Similarity
messages: Belongs to the hyi family.

1091494:MEALZ RS12805
gene id: 1091494:MEALZ_RS12805
uniprot id: G4SXZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1091494:MEALZ RS04030
gene id: 1091494:MEALZ_RS04030
uniprot id: G4T2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1091494:MEALZ RS15195
gene id: 1091494:MEALZ_RS15195
uniprot id: G4T333
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1091494:MEALZ RS12880
gene id: 1091494:MEALZ_RS12880
uniprot id: G4SY13
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1091494:MEALZ RS04635
gene id: 1091494:MEALZ_RS04635
uniprot id: G4T3V0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1091494:MEALZ RS04525
gene id: 1091494:MEALZ_RS04525
uniprot id: G4T3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1091494:MEALZ RS20645
gene id: 1091494:MEALZ_RS20645
uniprot id: G4SVG6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS19645
gene id: 1091494:MEALZ_RS19645
uniprot id: G4T1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1091494:MEALZ RS07725
gene id: 1091494:MEALZ_RS07725
uniprot id: G4SZD5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1091494:MEALZ RS01645
gene id: 1091494:MEALZ_RS01645
uniprot id: G4SWW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1091494:MEALZ RS03935
gene id: 1091494:MEALZ_RS03935
uniprot id: G4T283
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1091494:MEALZ RS00410
gene id: 1091494:MEALZ_RS00410
uniprot id: G4SUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1091494:MEALZ RS10950
gene id: 1091494:MEALZ_RS10950
uniprot id: G4STG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1091494:MEALZ RS04830
gene id: 1091494:MEALZ_RS04830
uniprot id: G4T3Y6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1091494:MEALZ RS12670
gene id: 1091494:MEALZ_RS12670
uniprot id: G4SXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1091494:MEALZ RS02440
gene id: 1091494:MEALZ_RS02440
uniprot id: G4SZ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1091494:MEALZ RS14800
gene id: 1091494:MEALZ_RS14800
uniprot id: G4T2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1091494:MEALZ RS13875
gene id: 1091494:MEALZ_RS13875
uniprot id: G4T0C6
names: Similarity
messages: Belongs to the XFP family.

1091494:MEALZ RS19460
gene id: 1091494:MEALZ_RS19460
uniprot id: G4T0L6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1091494:MEALZ RS00655
gene id: 1091494:MEALZ_RS00655
uniprot id: G4SUK0
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS01755
gene id: 1091494:MEALZ_RS01755
uniprot id: G4SXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1091494:MEALZ RS03205
gene id: 1091494:MEALZ_RS03205
uniprot id: G4T0S4
names: Similarity
messages: Belongs to the TelA family.

1091494:MEALZ RS15510
gene id: 1091494:MEALZ_RS15510
uniprot id: G4T3N6
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS14945
gene id: 1091494:MEALZ_RS14945
uniprot id: G4T2J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1091494:MEALZ RS01505
gene id: 1091494:MEALZ_RS01505
uniprot id: G4SWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1091494:MEALZ RS02800
gene id: 1091494:MEALZ_RS02800
uniprot id: G4SZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS02685
gene id: 1091494:MEALZ_RS02685
uniprot id: G4SZ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1091494:MEALZ RS17190
gene id: 1091494:MEALZ_RS17190
uniprot id: G4SVT7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1091494:MEALZ RS02655
gene id: 1091494:MEALZ_RS02655
uniprot id: G4SZ90
names: Similarity
messages: Belongs to the DEAD box helicase family.

1091494:MEALZ RS09280
gene id: 1091494:MEALZ_RS09280
uniprot id: G4T2D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1091494:MEALZ RS14260
gene id: 1091494:MEALZ_RS14260
uniprot id: G4T162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane

1091494:MEALZ RS17160
gene id: 1091494:MEALZ_RS17160
uniprot id: G4SVT1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1091494:MEALZ RS19915
gene id: 1091494:MEALZ_RS19915
uniprot id: G4T217
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS16290
gene id: 1091494:MEALZ_RS16290
uniprot id: G4STK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1091494:MEALZ RS14095
gene id: 1091494:MEALZ_RS14095
uniprot id: G4T129
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1091494:MEALZ RS07665
gene id: 1091494:MEALZ_RS07665
uniprot id: G4SZC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1091494:MEALZ RS01595
gene id: 1091494:MEALZ_RS01595
uniprot id: G4SWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1091494:MEALZ RS18605
gene id: 1091494:MEALZ_RS18605
uniprot id: G4SYZ5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS06240
gene id: 1091494:MEALZ_RS06240
uniprot id: G4SVJ7
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14190
gene id: 1091494:MEALZ_RS14190
uniprot id: G4T148
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1091494:MEALZ RS06750
gene id: 1091494:MEALZ_RS06750
uniprot id: G4SX16
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1091494:MEALZ RS06030
gene id: 1091494:MEALZ_RS06030
uniprot id: G4SVF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1091494:MEALZ RS18390
gene id: 1091494:MEALZ_RS18390
uniprot id: G4SY96
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1091494:MEALZ RS11635
gene id: 1091494:MEALZ_RS11635
uniprot id: G4SUZ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1091494:MEALZ RS02045
gene id: 1091494:MEALZ_RS02045
uniprot id: G4SXR0
names: Similarity
messages: Belongs to the UPF0276 family.

1091494:MEALZ RS17405
gene id: 1091494:MEALZ_RS17405
uniprot id: G4SVX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1091494:MEALZ RS09145
gene id: 1091494:MEALZ_RS09145
uniprot id: G4T2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1091494:MEALZ RS13300
gene id: 1091494:MEALZ_RS13300
uniprot id: G4SYV6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00765
gene id: 1091494:MEALZ_RS00765
uniprot id: G4SV74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS11345
gene id: 1091494:MEALZ_RS11345
uniprot id: G4SUT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1091494:MEALZ RS12745
gene id: 1091494:MEALZ_RS12745
uniprot id: G4SXY4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS16220
gene id: 1091494:MEALZ_RS16220
uniprot id: G4STI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1091494:MEALZ RS12680
gene id: 1091494:MEALZ_RS12680
uniprot id: G4SXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1091494:MEALZ RS01815
gene id: 1091494:MEALZ_RS01815
uniprot id: G4SXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1091494:MEALZ RS11665
gene id: 1091494:MEALZ_RS11665
uniprot id: G4SVK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS02140
gene id: 1091494:MEALZ_RS02140
uniprot id: G4SYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1091494:MEALZ RS20410
gene id: 1091494:MEALZ_RS20410
uniprot id: G4T4P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1091494:MEALZ RS16115
gene id: 1091494:MEALZ_RS16115
uniprot id: G4STG9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homotetramer.
messages: Non-allosteric.

1091494:MEALZ RS13025
gene id: 1091494:MEALZ_RS13025
uniprot id: G4SY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS02675
gene id: 1091494:MEALZ_RS02675
uniprot id: G4SZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1091494:MEALZ RS13865
gene id: 1091494:MEALZ_RS13865
uniprot id: G4T0C4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1091494:MEALZ RS06525
gene id: 1091494:MEALZ_RS06525
uniprot id: G4SWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1091494:MEALZ RS04975
gene id: 1091494:MEALZ_RS04975
uniprot id: G4ST05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1091494:MEALZ RS15435
gene id: 1091494:MEALZ_RS15435
uniprot id: G4T382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1091494:MEALZ RS19025
gene id: 1091494:MEALZ_RS19025
uniprot id: G4SZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1091494:MEALZ RS11520
gene id: 1091494:MEALZ_RS11520
uniprot id: G4SUX1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS09410
gene id: 1091494:MEALZ_RS09410
uniprot id: G4T2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1091494:MEALZ RS06880
gene id: 1091494:MEALZ_RS06880
uniprot id: G4SX43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1091494:MEALZ RS06490
gene id: 1091494:MEALZ_RS06490
uniprot id: G4SWA4
names: Similarity
messages: Belongs to the universal stress protein A family.

1091494:MEALZ RS15430
gene id: 1091494:MEALZ_RS15430
uniprot id: G4T381
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1091494:MEALZ RS11835
gene id: 1091494:MEALZ_RS11835
uniprot id: G4SVP2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1091494:MEALZ RS02550
gene id: 1091494:MEALZ_RS02550
uniprot id: G4SZ66
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS04060
gene id: 1091494:MEALZ_RS04060
uniprot id: G4T2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1091494:MEALZ RS00430
gene id: 1091494:MEALZ_RS00430
uniprot id: G4SUG3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1091494:MEALZ RS17660
gene id: 1091494:MEALZ_RS17660
uniprot id: G4SWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1091494:MEALZ RS02445
gene id: 1091494:MEALZ_RS02445
uniprot id: G4SZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1091494:MEALZ RS07700
gene id: 1091494:MEALZ_RS07700
uniprot id: G4SZC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1091494:MEALZ RS15465
gene id: 1091494:MEALZ_RS15465
uniprot id: G4T3M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1091494:MEALZ RS18910
gene id: 1091494:MEALZ_RS18910
uniprot id: G4SZR1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1091494:MEALZ RS12025
gene id: 1091494:MEALZ_RS12025
uniprot id: G4SWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1091494:MEALZ RS17715
gene id: 1091494:MEALZ_RS17715
uniprot id: G4SWP6
names: Similarity
messages: Belongs to the UPF0102 family.

1091494:MEALZ RS00825
gene id: 1091494:MEALZ_RS00825
uniprot id: G4SV85
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1091494:MEALZ RS16995
gene id: 1091494:MEALZ_RS16995
uniprot id: G4SV36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19205
gene id: 1091494:MEALZ_RS19205
uniprot id: G4T0G3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS05335
gene id: 1091494:MEALZ_RS05335
uniprot id: G4STW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS08095
gene id: 1091494:MEALZ_RS08095
uniprot id: G4T058
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1091494:MEALZ RS04520
gene id: 1091494:MEALZ_RS04520
uniprot id: G4T3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1091494:MEALZ RS09365
gene id: 1091494:MEALZ_RS09365
uniprot id: G4T2F4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17735
gene id: 1091494:MEALZ_RS17735
uniprot id: G4SWQ0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1091494:MEALZ RS00280
gene id: 1091494:MEALZ_RS00280
uniprot id: G4STT7
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09810
gene id: 1091494:MEALZ_RS09810
uniprot id: G4T3G0
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00010
gene id: 1091494:MEALZ_RS00010
uniprot id: G4STN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1091494:MEALZ RS12220
gene id: 1091494:MEALZ_RS12220
uniprot id: G4SWG3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1091494:MEALZ RS12665
gene id: 1091494:MEALZ_RS12665
uniprot id: G4SXB1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1091494:MEALZ RS23415
gene id: 1091494:MEALZ_RS23415
uniprot id: G4T300
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14850
gene id: 1091494:MEALZ_RS14850
uniprot id: G4T2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS17935
gene id: 1091494:MEALZ_RS17935
uniprot id: G4SXF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1091494:MEALZ RS20100
gene id: 1091494:MEALZ_RS20100
uniprot id: G4T4I8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14410
gene id: 1091494:MEALZ_RS14410
uniprot id: G4T1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1091494:MEALZ RS04400
gene id: 1091494:MEALZ_RS04400
uniprot id: G4T3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1091494:MEALZ RS07145
gene id: 1091494:MEALZ_RS07145
uniprot id: G4SXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1091494:MEALZ RS15750
gene id: 1091494:MEALZ_RS15750
uniprot id: G4T3T7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1091494:MEALZ RS12815
gene id: 1091494:MEALZ_RS12815
uniprot id: G4SXZ9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS09070
gene id: 1091494:MEALZ_RS09070
uniprot id: G4T296
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1091494:MEALZ RS16480
gene id: 1091494:MEALZ_RS16480
uniprot id: G4SU84
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1091494:MEALZ RS04225
gene id: 1091494:MEALZ_RS04225
uniprot id: G4T2T6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS16465
gene id: 1091494:MEALZ_RS16465
uniprot id: G4SU82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1091494:MEALZ RS16595
gene id: 1091494:MEALZ_RS16595
uniprot id: G4SUA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1091494:MEALZ RS16750
gene id: 1091494:MEALZ_RS16750
uniprot id: G4SUD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1091494:MEALZ RS15290
gene id: 1091494:MEALZ_RS15290
uniprot id: G4T353
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1091494:MEALZ RS11890
gene id: 1091494:MEALZ_RS11890
uniprot id: G4SVQ3
names: Similarity
messages: Belongs to the HisA/HisF family.

1091494:MEALZ RS08300
gene id: 1091494:MEALZ_RS08300
uniprot id: G4T0V6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1091494:MEALZ RS17605
gene id: 1091494:MEALZ_RS17605
uniprot id: G4SWM4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1091494:MEALZ RS06590
gene id: 1091494:MEALZ_RS06590
uniprot id: G4SWY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1091494:MEALZ RS11825
gene id: 1091494:MEALZ_RS11825
uniprot id: G4SVN9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS17990
gene id: 1091494:MEALZ_RS17990
uniprot id: G4SXG2
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS12810
gene id: 1091494:MEALZ_RS12810
uniprot id: G4SXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1091494:MEALZ RS15900
gene id: 1091494:MEALZ_RS15900
uniprot id: G4T4B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS17640
gene id: 1091494:MEALZ_RS17640
uniprot id: G4SWN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1091494:MEALZ RS02920
gene id: 1091494:MEALZ_RS02920
uniprot id: G4T005
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1091494:MEALZ RS15450
gene id: 1091494:MEALZ_RS15450
uniprot id: G4T3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1091494:MEALZ RS15420
gene id: 1091494:MEALZ_RS15420
uniprot id: G4T379
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1091494:MEALZ RS03230
gene id: 1091494:MEALZ_RS03230
uniprot id: G4T0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1091494:MEALZ RS09790
gene id: 1091494:MEALZ_RS09790
uniprot id: G4T3F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS14085
gene id: 1091494:MEALZ_RS14085
uniprot id: G4T127
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS15055
gene id: 1091494:MEALZ_RS15055
uniprot id: G4T2L6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1091494:MEALZ RS12400
gene id: 1091494:MEALZ_RS12400
uniprot id: G4SWJ5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1091494:MEALZ RS14950
gene id: 1091494:MEALZ_RS14950
uniprot id: G4T2J6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1091494:MEALZ RS15770
gene id: 1091494:MEALZ_RS15770
uniprot id: G4T485
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1091494:MEALZ RS03100
gene id: 1091494:MEALZ_RS03100
uniprot id: G4T0Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS01825
gene id: 1091494:MEALZ_RS01825
uniprot id: G4SXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1091494:MEALZ RS01260
gene id: 1091494:MEALZ_RS01260
uniprot id: G4SW36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1091494:MEALZ RS17230
gene id: 1091494:MEALZ_RS17230
uniprot id: G4SVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1091494:MEALZ RS11620
gene id: 1091494:MEALZ_RS11620
uniprot id: G4SUZ5
names: Similarity
messages: Belongs to the ModE family.

1091494:MEALZ RS06635
gene id: 1091494:MEALZ_RS06635
uniprot id: G4SWZ3
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1091494:MEALZ RS10495
gene id: 1091494:MEALZ_RS10495
uniprot id: G4ST77
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16865
gene id: 1091494:MEALZ_RS16865
uniprot id: G4SV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

1091494:MEALZ RS13590
gene id: 1091494:MEALZ_RS13590
uniprot id: G4SZL8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1091494:MEALZ RS01960
gene id: 1091494:MEALZ_RS01960
uniprot id: G4SXP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1091494:MEALZ RS15860
gene id: 1091494:MEALZ_RS15860
uniprot id: G4T4A3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1091494:MEALZ RS19230
gene id: 1091494:MEALZ_RS19230
uniprot id: G4T0G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1091494:MEALZ RS09235
gene id: 1091494:MEALZ_RS09235
uniprot id: G4T2C8
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1091494:MEALZ RS23465
gene id: 1091494:MEALZ_RS23465
uniprot id: G4SWJ4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1091494:MEALZ RS13095
gene id: 1091494:MEALZ_RS13095
uniprot id: G4SYR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1091494:MEALZ RS08840
gene id: 1091494:MEALZ_RS08840
uniprot id: G4T1Q9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS16725
gene id: 1091494:MEALZ_RS16725
uniprot id: G4SUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1091494:MEALZ RS05015
gene id: 1091494:MEALZ_RS05015
uniprot id: G4ST13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1091494:MEALZ RS10510
gene id: 1091494:MEALZ_RS10510
uniprot id: G4ST80
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS09215
gene id: 1091494:MEALZ_RS09215
uniprot id: G4T2C5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1091494:MEALZ RS12195
gene id: 1091494:MEALZ_RS12195
uniprot id: G4SWF8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1091494:MEALZ RS00740
gene id: 1091494:MEALZ_RS00740
uniprot id: G4SV67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS00105
gene id: 1091494:MEALZ_RS00105
uniprot id: G4STQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS04545
gene id: 1091494:MEALZ_RS04545
uniprot id: G4T3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1091494:MEALZ RS09920
gene id: 1091494:MEALZ_RS09920
uniprot id: G4T3I3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1091494:MEALZ RS02490
gene id: 1091494:MEALZ_RS02490
uniprot id: G4SZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1091494:MEALZ RS04335
gene id: 1091494:MEALZ_RS04335
uniprot id: G4T399
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1091494:MEALZ RS15200
gene id: 1091494:MEALZ_RS15200
uniprot id: G4T334
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1091494:MEALZ RS07635
gene id: 1091494:MEALZ_RS07635
uniprot id: G4SZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1091494:MEALZ RS16425
gene id: 1091494:MEALZ_RS16425
uniprot id: G4STN2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1091494:MEALZ RS04125
gene id: 1091494:MEALZ_RS04125
uniprot id: G4T2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS09530
gene id: 1091494:MEALZ_RS09530
uniprot id: G4T2X1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1091494:MEALZ RS09015
gene id: 1091494:MEALZ_RS09015
uniprot id: G4T1U3
names: Similarity
messages: Belongs to the BolA/IbaG family.

1091494:MEALZ RS13575
gene id: 1091494:MEALZ_RS13575
uniprot id: G4SZL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1091494:MEALZ RS03450
gene id: 1091494:MEALZ_RS03450
uniprot id: G4T1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS00905
gene id: 1091494:MEALZ_RS00905
uniprot id: G4SVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1091494:MEALZ RS03080
gene id: 1091494:MEALZ_RS03080
uniprot id: G4T0P9
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1091494:MEALZ RS16430
gene id: 1091494:MEALZ_RS16430
uniprot id: G4STM7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1091494:MEALZ RS16280
gene id: 1091494:MEALZ_RS16280
uniprot id: G4STJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1091494:MEALZ RS04340
gene id: 1091494:MEALZ_RS04340
uniprot id: G4T3A0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1091494:MEALZ RS15030
gene id: 1091494:MEALZ_RS15030
uniprot id: G4T2L1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1091494:MEALZ RS10920
gene id: 1091494:MEALZ_RS10920
uniprot id: G4STF4
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1091494:MEALZ RS14210
gene id: 1091494:MEALZ_RS14210
uniprot id: G4T152
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1091494:MEALZ RS16395
gene id: 1091494:MEALZ_RS16395
uniprot id: G4STM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1091494:MEALZ RS17915
gene id: 1091494:MEALZ_RS17915
uniprot id: G4SXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1091494:MEALZ RS17180
gene id: 1091494:MEALZ_RS17180
uniprot id: G4SVT5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1091494:MEALZ RS07160
gene id: 1091494:MEALZ_RS07160
uniprot id: G4SXW0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1091494:MEALZ RS01760
gene id: 1091494:MEALZ_RS01760
uniprot id: G4SXK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS08390
gene id: 1091494:MEALZ_RS08390
uniprot id: G4T0X4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09045
gene id: 1091494:MEALZ_RS09045
uniprot id: G4T291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1091494:MEALZ RS00405
gene id: 1091494:MEALZ_RS00405
uniprot id: G4SUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1091494:MEALZ RS15690
gene id: 1091494:MEALZ_RS15690
uniprot id: G4T3S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1091494:MEALZ RS15720
gene id: 1091494:MEALZ_RS15720
uniprot id: G4T3S9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1091494:MEALZ RS11205
gene id: 1091494:MEALZ_RS11205
uniprot id: G4SU64
names: Similarity
messages: Belongs to the barstar family.

1091494:MEALZ RS08875
gene id: 1091494:MEALZ_RS08875
uniprot id: G4T1R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS10070
gene id: 1091494:MEALZ_RS10070
uniprot id: G4T3M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1091494:MEALZ RS17375
gene id: 1091494:MEALZ_RS17375
uniprot id: G4SVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1091494:MEALZ RS19060
gene id: 1091494:MEALZ_RS19060
uniprot id: G4SZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1091494:MEALZ RS03150
gene id: 1091494:MEALZ_RS03150
uniprot id: G4T0R3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1091494:MEALZ RS16190
gene id: 1091494:MEALZ_RS16190
uniprot id: G4STI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1091494:MEALZ RS07890
gene id: 1091494:MEALZ_RS07890
uniprot id: G4SZG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1091494:MEALZ RS17745
gene id: 1091494:MEALZ_RS17745
uniprot id: G4SWQ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1091494:MEALZ RS02755
gene id: 1091494:MEALZ_RS02755
uniprot id: G4SZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1091494:MEALZ RS00490
gene id: 1091494:MEALZ_RS00490
uniprot id: G4SUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1091494:MEALZ RS06595
gene id: 1091494:MEALZ_RS06595
uniprot id: G4SWY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1091494:MEALZ RS08000
gene id: 1091494:MEALZ_RS08000
uniprot id: G4T038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

1091494:MEALZ RS17620
gene id: 1091494:MEALZ_RS17620
uniprot id: G4SWM6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1091494:MEALZ RS15025
gene id: 1091494:MEALZ_RS15025
uniprot id: G4T2L0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1091494:MEALZ RS16185
gene id: 1091494:MEALZ_RS16185
uniprot id: G4STI0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS16250
gene id: 1091494:MEALZ_RS16250
uniprot id: G4STJ3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1091494:MEALZ RS02465
gene id: 1091494:MEALZ_RS02465
uniprot id: G4SZ49
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1091494:MEALZ RS04600
gene id: 1091494:MEALZ_RS04600
uniprot id: G4T3U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1091494:MEALZ RS19695
gene id: 1091494:MEALZ_RS19695
uniprot id: G4T1B7
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17760
gene id: 1091494:MEALZ_RS17760
uniprot id: G4SWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1091494:MEALZ RS13505
gene id: 1091494:MEALZ_RS13505
uniprot id: G4SZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS04670
gene id: 1091494:MEALZ_RS04670
uniprot id: G4T3V6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1091494:MEALZ RS08230
gene id: 1091494:MEALZ_RS08230
uniprot id: G4T087
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1091494:MEALZ RS16305
gene id: 1091494:MEALZ_RS16305
uniprot id: G4STK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1091494:MEALZ RS07695
gene id: 1091494:MEALZ_RS07695
uniprot id: G4SZC8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1091494:MEALZ RS02230
gene id: 1091494:MEALZ_RS02230
uniprot id: G4SYF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1091494:MEALZ RS18820
gene id: 1091494:MEALZ_RS18820
uniprot id: G4SZ34
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1091494:MEALZ RS04775
gene id: 1091494:MEALZ_RS04775
uniprot id: G4T3X6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1091494:MEALZ RS01205
gene id: 1091494:MEALZ_RS01205
uniprot id: G4SW23
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1091494:MEALZ RS14930
gene id: 1091494:MEALZ_RS14930
uniprot id: G4T2J2
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS03435
gene id: 1091494:MEALZ_RS03435
uniprot id: G4T1I2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1091494:MEALZ RS15715
gene id: 1091494:MEALZ_RS15715
uniprot id: G4T3S8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1091494:MEALZ RS01785
gene id: 1091494:MEALZ_RS01785
uniprot id: G4SXK8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1091494:MEALZ RS05045
gene id: 1091494:MEALZ_RS05045
uniprot id: G4ST18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1091494:MEALZ RS00480
gene id: 1091494:MEALZ_RS00480
uniprot id: G4SUH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1091494:MEALZ RS08075
gene id: 1091494:MEALZ_RS08075
uniprot id: G4T054
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1091494:MEALZ RS07540
gene id: 1091494:MEALZ_RS07540
uniprot id: G4SYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1091494:MEALZ RS17030
gene id: 1091494:MEALZ_RS17030
uniprot id: G4SV44
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1091494:MEALZ RS03295
gene id: 1091494:MEALZ_RS03295
uniprot id: G4T0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1091494:MEALZ RS23555
gene id: 1091494:MEALZ_RS23555
uniprot id: G4T0K5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1091494:MEALZ RS16340
gene id: 1091494:MEALZ_RS16340
uniprot id: G4STL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1091494:MEALZ RS15100
gene id: 1091494:MEALZ_RS15100
uniprot id: G4T2M6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1091494:MEALZ RS14460
gene id: 1091494:MEALZ_RS14460
uniprot id: G4T1V9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1091494:MEALZ RS16335
gene id: 1091494:MEALZ_RS16335
uniprot id: G4STL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1091494:MEALZ RS08680
gene id: 1091494:MEALZ_RS08680
uniprot id: G4T1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1091494:MEALZ RS05575
gene id: 1091494:MEALZ_RS05575
uniprot id: G4SU09
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1091494:MEALZ RS11840
gene id: 1091494:MEALZ_RS11840
uniprot id: G4SVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Membrane

1091494:MEALZ RS17730
gene id: 1091494:MEALZ_RS17730
uniprot id: G4SWP9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1091494:MEALZ RS14415
gene id: 1091494:MEALZ_RS14415
uniprot id: G4T1V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1091494:MEALZ RS12090
gene id: 1091494:MEALZ_RS12090
uniprot id: G4SWD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS02815
gene id: 1091494:MEALZ_RS02815
uniprot id: G4SZY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS14890
gene id: 1091494:MEALZ_RS14890
uniprot id: G4T2I5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1091494:MEALZ RS09105
gene id: 1091494:MEALZ_RS09105
uniprot id: G4T2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1091494:MEALZ RS19485
gene id: 1091494:MEALZ_RS19485
uniprot id: G4T0M0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1091494:MEALZ RS15270
gene id: 1091494:MEALZ_RS15270
uniprot id: G4T349
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1091494:MEALZ RS08775
gene id: 1091494:MEALZ_RS08775
uniprot id: G4T1P6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1091494:MEALZ RS14520
gene id: 1091494:MEALZ_RS14520
uniprot id: G4T1X1
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS04845
gene id: 1091494:MEALZ_RS04845
uniprot id: G4T3Y9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1091494:MEALZ RS06275
gene id: 1091494:MEALZ_RS06275
uniprot id: G4SW61
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1091494:MEALZ RS16315
gene id: 1091494:MEALZ_RS16315
uniprot id: G4STK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1091494:MEALZ RS17420
gene id: 1091494:MEALZ_RS17420
uniprot id: G4SVX6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1091494:MEALZ RS16820
gene id: 1091494:MEALZ_RS16820
uniprot id: G4SV01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1091494:MEALZ RS19715
gene id: 1091494:MEALZ_RS19715
uniprot id: G4T1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS16165
gene id: 1091494:MEALZ_RS16165
uniprot id: G4STH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19660
gene id: 1091494:MEALZ_RS19660
uniprot id: G4T1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1091494:MEALZ RS02620
gene id: 1091494:MEALZ_RS02620
uniprot id: G4SZ82
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1091494:MEALZ RS09775
gene id: 1091494:MEALZ_RS09775
uniprot id: G4T3F3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1091494:MEALZ RS01965
gene id: 1091494:MEALZ_RS01965
uniprot id: G4SXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS06710
gene id: 1091494:MEALZ_RS06710
uniprot id: G4SX08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS17740
gene id: 1091494:MEALZ_RS17740
uniprot id: G4SWQ1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1091494:MEALZ RS00665
gene id: 1091494:MEALZ_RS00665
uniprot id: G4SUK2
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1091494:MEALZ RS15170
gene id: 1091494:MEALZ_RS15170
uniprot id: G4T328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1091494:MEALZ RS07800
gene id: 1091494:MEALZ_RS07800
uniprot id: G4SZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1091494:MEALZ RS14720
gene id: 1091494:MEALZ_RS14720
uniprot id: G4T208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1091494:MEALZ RS11965
gene id: 1091494:MEALZ_RS11965
uniprot id: G4SVR8
names: Similarity
messages: Belongs to the peptidase S16 family.

1091494:MEALZ RS09395
gene id: 1091494:MEALZ_RS09395
uniprot id: G4T2U5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

1091494:MEALZ RS08830
gene id: 1091494:MEALZ_RS08830
uniprot id: G4T1Q7
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1091494:MEALZ RS07245
gene id: 1091494:MEALZ_RS07245
uniprot id: G4SXX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1091494:MEALZ RS03005
gene id: 1091494:MEALZ_RS03005
uniprot id: G4T0N3
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS19310
gene id: 1091494:MEALZ_RS19310
uniprot id: G4T0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS11225
gene id: 1091494:MEALZ_RS11225
uniprot id: G4SU68
names: Similarity
messages: Belongs to the CutA family.

1091494:MEALZ RS11250
gene id: 1091494:MEALZ_RS11250
uniprot id: G4SU73
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1091494:MEALZ RS09310
gene id: 1091494:MEALZ_RS09310
uniprot id: G4T2E3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1091494:MEALZ RS09195
gene id: 1091494:MEALZ_RS09195
uniprot id: G4T2C1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1091494:MEALZ RS06375
gene id: 1091494:MEALZ_RS06375
uniprot id: G4SW81
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1091494:MEALZ RS17580
gene id: 1091494:MEALZ_RS17580
uniprot id: G4SWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS19590
gene id: 1091494:MEALZ_RS19590
uniprot id: G4T195
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1091494:MEALZ RS05025
gene id: 1091494:MEALZ_RS05025
uniprot id: G4ST15
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1091494:MEALZ RS12675
gene id: 1091494:MEALZ_RS12675
uniprot id: G4SXB3
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1091494:MEALZ RS11255
gene id: 1091494:MEALZ_RS11255
uniprot id: G4SU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1091494:MEALZ RS16935
gene id: 1091494:MEALZ_RS16935
uniprot id: G4SV24
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1091494:MEALZ RS07305
gene id: 1091494:MEALZ_RS07305
uniprot id: G4SYJ8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1091494:MEALZ RS00625
gene id: 1091494:MEALZ_RS00625
uniprot id: G4SUJ4
names: Similarity
messages: Belongs to the SCO1/2 family.

1091494:MEALZ RS07575
gene id: 1091494:MEALZ_RS07575
uniprot id: G4SZA4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS17920
gene id: 1091494:MEALZ_RS17920
uniprot id: G4SXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1091494:MEALZ RS10965
gene id: 1091494:MEALZ_RS10965
uniprot id: G4STG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1091494:MEALZ RS10515
gene id: 1091494:MEALZ_RS10515
uniprot id: G4ST81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS19400
gene id: 1091494:MEALZ_RS19400
uniprot id: G4T0K6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1091494:MEALZ RS13440
gene id: 1091494:MEALZ_RS13440
uniprot id: G4SZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1091494:MEALZ RS05035
gene id: 1091494:MEALZ_RS05035
uniprot id: G4ST17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1091494:MEALZ RS05890
gene id: 1091494:MEALZ_RS05890
uniprot id: G4SUS2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1091494:MEALZ RS14560
gene id: 1091494:MEALZ_RS14560
uniprot id: G4T1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS15655
gene id: 1091494:MEALZ_RS15655
uniprot id: G4T3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1091494:MEALZ RS03895
gene id: 1091494:MEALZ_RS03895
uniprot id: G4T274
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS12795
gene id: 1091494:MEALZ_RS12795
uniprot id: G4SXZ5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1091494:MEALZ RS04540
gene id: 1091494:MEALZ_RS04540
uniprot id: G4T3D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1091494:MEALZ RS17295
gene id: 1091494:MEALZ_RS17295
uniprot id: G4SVV7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS07570
gene id: 1091494:MEALZ_RS07570
uniprot id: G4SZA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1091494:MEALZ RS03185
gene id: 1091494:MEALZ_RS03185
uniprot id: G4T0S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1091494:MEALZ RS07130
gene id: 1091494:MEALZ_RS07130
uniprot id: G4SXV4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS13935
gene id: 1091494:MEALZ_RS13935
uniprot id: G4T0D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1091494:MEALZ RS14230
gene id: 1091494:MEALZ_RS14230
uniprot id: G4T156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1091494:MEALZ RS18595
gene id: 1091494:MEALZ_RS18595
uniprot id: G4SYZ3
names: Similarity
messages: Belongs to the YoeB family.

1091494:MEALZ RS11245
gene id: 1091494:MEALZ_RS11245
uniprot id: G4SU72
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1091494:MEALZ RS14110
gene id: 1091494:MEALZ_RS14110
uniprot id: G4T131
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS20775
gene id: 1091494:MEALZ_RS20775
uniprot id: G4SY11
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS14745
gene id: 1091494:MEALZ_RS14745
uniprot id: G4T212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS16495
gene id: 1091494:MEALZ_RS16495
uniprot id: G4SU87
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1091494:MEALZ RS06420
gene id: 1091494:MEALZ_RS06420
uniprot id: G4SW91
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1091494:MEALZ RS13415
gene id: 1091494:MEALZ_RS13415
uniprot id: G4SZI5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1091494:MEALZ RS19890
gene id: 1091494:MEALZ_RS19890
uniprot id: G4T1F2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1091494:MEALZ RS15340
gene id: 1091494:MEALZ_RS15340
uniprot id: G4T365
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1091494:MEALZ RS04135
gene id: 1091494:MEALZ_RS04135
uniprot id: G4T2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS15695
gene id: 1091494:MEALZ_RS15695
uniprot id: G4T3S5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1091494:MEALZ RS07155
gene id: 1091494:MEALZ_RS07155
uniprot id: G4SXV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1091494:MEALZ RS14785
gene id: 1091494:MEALZ_RS14785
uniprot id: G4T2G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1091494:MEALZ RS21080
gene id: 1091494:MEALZ_RS21080
uniprot id: G4SXH4
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS11145
gene id: 1091494:MEALZ_RS11145
uniprot id: G4SU52
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS10970
gene id: 1091494:MEALZ_RS10970
uniprot id: G4STG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1091494:MEALZ RS13700
gene id: 1091494:MEALZ_RS13700
uniprot id: G4SZP5
names: Similarity
messages: Belongs to the peptidase S8 family.

1091494:MEALZ RS07175
gene id: 1091494:MEALZ_RS07175
uniprot id: G4SXW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1091494:MEALZ RS04005
gene id: 1091494:MEALZ_RS04005
uniprot id: G4T2N8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS01430
gene id: 1091494:MEALZ_RS01430
uniprot id: G4SWS5
names: Similarity
messages: Belongs to the YoeB family.

1091494:MEALZ RS16300
gene id: 1091494:MEALZ_RS16300
uniprot id: G4STK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1091494:MEALZ RS01140
gene id: 1091494:MEALZ_RS01140
uniprot id: G4SW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS12105
gene id: 1091494:MEALZ_RS12105
uniprot id: G4SWE2
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS01895
gene id: 1091494:MEALZ_RS01895
uniprot id: G4SXM9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1091494:MEALZ RS04555
gene id: 1091494:MEALZ_RS04555
uniprot id: G4T3E1
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1091494:MEALZ RS04385
gene id: 1091494:MEALZ_RS04385
uniprot id: G4T3A8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1091494:MEALZ RS09290
gene id: 1091494:MEALZ_RS09290
uniprot id: G4T2D9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS04470
gene id: 1091494:MEALZ_RS04470
uniprot id: G4T3C5
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS04325
gene id: 1091494:MEALZ_RS04325
uniprot id: G4T397
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS00530
gene id: 1091494:MEALZ_RS00530
uniprot id: G4SUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1091494:MEALZ RS19095
gene id: 1091494:MEALZ_RS19095
uniprot id: G4SZU5
names: Similarity
messages: Belongs to the LOG family.

1091494:MEALZ RS03010
gene id: 1091494:MEALZ_RS03010
uniprot id: G4T0N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1091494:MEALZ RS15460
gene id: 1091494:MEALZ_RS15460
uniprot id: G4T3M6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1091494:MEALZ RS05945
gene id: 1091494:MEALZ_RS05945
uniprot id: G4SVD8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00675
gene id: 1091494:MEALZ_RS00675
uniprot id: G4SUK4
names: Similarity
messages: Belongs to the UPF0758 family.

1091494:MEALZ RS04235
gene id: 1091494:MEALZ_RS04235
uniprot id: G4T2T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS08060
gene id: 1091494:MEALZ_RS08060
uniprot id: G4T051
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS13555
gene id: 1091494:MEALZ_RS13555
uniprot id: G4SZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm

1091494:MEALZ RS08970
gene id: 1091494:MEALZ_RS08970
uniprot id: G4T1T4
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 8 heme c groups per subunit. One specific heme c group is called heme P460.
messages: Binds 8 heme groups per subunit.
messages: Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554.
messages: Homotrimer.
messages: Periplasm

1091494:MEALZ RS16805
gene id: 1091494:MEALZ_RS16805
uniprot id: G4SUE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1091494:MEALZ RS10700
gene id: 1091494:MEALZ_RS10700
uniprot id: G4STB7
names: Similarity
messages: Belongs to the UPF0229 family.

1091494:MEALZ RS15320
gene id: 1091494:MEALZ_RS15320
uniprot id: G4T360
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1091494:MEALZ RS17135
gene id: 1091494:MEALZ_RS17135
uniprot id: G4SV63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1091494:MEALZ RS07545
gene id: 1091494:MEALZ_RS07545
uniprot id: G4SYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS19300
gene id: 1091494:MEALZ_RS19300
uniprot id: G4T0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS07715
gene id: 1091494:MEALZ_RS07715
uniprot id: G4SZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1091494:MEALZ RS01245
gene id: 1091494:MEALZ_RS01245
uniprot id: G4SW32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1091494:MEALZ RS15260
gene id: 1091494:MEALZ_RS15260
uniprot id: G4T347
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1091494:MEALZ RS02830
gene id: 1091494:MEALZ_RS02830
uniprot id: G4SZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1091494:MEALZ RS15855
gene id: 1091494:MEALZ_RS15855
uniprot id: G4T4A2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1091494:MEALZ RS16410
gene id: 1091494:MEALZ_RS16410
uniprot id: G4STM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1091494:MEALZ RS14700
gene id: 1091494:MEALZ_RS14700
uniprot id: G4T204
names: Subcellular Location Annotation
messages: Cytoplasm

1091494:MEALZ RS10520
gene id: 1091494:MEALZ_RS10520
uniprot id: G4ST82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1091494:MEALZ RS13395
gene id: 1091494:MEALZ_RS13395
uniprot id: G4SZI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1091494:MEALZ RS09960
gene id: 1091494:MEALZ_RS09960
uniprot id: G4T3J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1091494:MEALZ RS04860
gene id: 1091494:MEALZ_RS04860
uniprot id: G4T3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1091494:MEALZ RS04065
gene id: 1091494:MEALZ_RS04065
uniprot id: G4T2Q1
names: Similarity
messages: Belongs to the DsrF/TusC family.

1091494:MEALZ RS07310
gene id: 1091494:MEALZ_RS07310
uniprot id: G4SYJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS14970
gene id: 1091494:MEALZ_RS14970
uniprot id: G4T2K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1091494:MEALZ RS07955
gene id: 1091494:MEALZ_RS07955
uniprot id: G4T029
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16570
gene id: 1091494:MEALZ_RS16570
uniprot id: G4SUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1091494:MEALZ RS16535
gene id: 1091494:MEALZ_RS16535
uniprot id: G4SU95
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1091494:MEALZ RS06370
gene id: 1091494:MEALZ_RS06370
uniprot id: G4SW80
names: Subunit
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1091494:MEALZ RS12755
gene id: 1091494:MEALZ_RS12755
uniprot id: G4SXY6
names: Similarity
messages: Belongs to the DapA family.

1091494:MEALZ RS03130
gene id: 1091494:MEALZ_RS03130
uniprot id: G4T0Q9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1091494:MEALZ RS19375
gene id: 1091494:MEALZ_RS19375
uniprot id: G4T0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1091494:MEALZ RS03710
gene id: 1091494:MEALZ_RS03710
uniprot id: G4T236
names: Similarity
messages: Belongs to the squalene monooxygenase family.

1091494:MEALZ RS09795
gene id: 1091494:MEALZ_RS09795
uniprot id: G4T3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1091494:MEALZ RS08855
gene id: 1091494:MEALZ_RS08855
uniprot id: G4T1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1091494:MEALZ RS05065
gene id: 1091494:MEALZ_RS05065
uniprot id: G4ST22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1091494:MEALZ RS17995
gene id: 1091494:MEALZ_RS17995
uniprot id: G4SXG3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1091494:MEALZ RS01145
gene id: 1091494:MEALZ_RS01145
uniprot id: G4SW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1091494:MEALZ RS18600
gene id: 1091494:MEALZ_RS18600
uniprot id: G4SYZ4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS02005
gene id: 1091494:MEALZ_RS02005
uniprot id: G4SXQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1091494:MEALZ RS18655
gene id: 1091494:MEALZ_RS18655
uniprot id: G4SZ05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1091494:MEALZ RS03815
gene id: 1091494:MEALZ_RS03815
uniprot id: G4T257
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1091494:MEALZ RS03465
gene id: 1091494:MEALZ_RS03465
uniprot id: G4T1I8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS05415
gene id: 1091494:MEALZ_RS05415
uniprot id: G4STY2
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS02795
gene id: 1091494:MEALZ_RS02795
uniprot id: G4SZX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1091494:MEALZ RS18805
gene id: 1091494:MEALZ_RS18805
uniprot id: G4SZ37
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS07270
gene id: 1091494:MEALZ_RS07270
uniprot id: G4SYJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS09415
gene id: 1091494:MEALZ_RS09415
uniprot id: G4T2U9
names: Similarity
messages: Belongs to the MotB family.

1091494:MEALZ RS14965
gene id: 1091494:MEALZ_RS14965
uniprot id: G4T2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1091494:MEALZ RS03400
gene id: 1091494:MEALZ_RS03400
uniprot id: G4T1H3
names: Similarity
messages: Belongs to the phosphorylase b kinase regulatory chain family.

1091494:MEALZ RS16035
gene id: 1091494:MEALZ_RS16035
uniprot id: G4T4E0
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS05090
gene id: 1091494:MEALZ_RS05090
uniprot id: G4ST27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1091494:MEALZ RS06600
gene id: 1091494:MEALZ_RS06600
uniprot id: G4SWY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1091494:MEALZ RS10730
gene id: 1091494:MEALZ_RS10730
uniprot id: G4STC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS17330
gene id: 1091494:MEALZ_RS17330
uniprot id: G4SVW4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1091494:MEALZ RS14395
gene id: 1091494:MEALZ_RS14395
uniprot id: G4T1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1091494:MEALZ RS07235
gene id: 1091494:MEALZ_RS07235
uniprot id: G4SXX6
names: Similarity
messages: Belongs to the TrpF family.

1091494:MEALZ RS04345
gene id: 1091494:MEALZ_RS04345
uniprot id: G4T3A1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1091494:MEALZ RS00390
gene id: 1091494:MEALZ_RS00390
uniprot id: G4SUF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS00400
gene id: 1091494:MEALZ_RS00400
uniprot id: G4SUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1091494:MEALZ RS06620
gene id: 1091494:MEALZ_RS06620
uniprot id: G4SWZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS07520
gene id: 1091494:MEALZ_RS07520
uniprot id: G4SYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1091494:MEALZ RS05420
gene id: 1091494:MEALZ_RS05420
uniprot id: G4STY3
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS18850
gene id: 1091494:MEALZ_RS18850
uniprot id: G4SZP9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1091494:MEALZ RS17125
gene id: 1091494:MEALZ_RS17125
uniprot id: G4SV61
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1091494:MEALZ RS14475
gene id: 1091494:MEALZ_RS14475
uniprot id: G4T1W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1091494:MEALZ RS18865
gene id: 1091494:MEALZ_RS18865
uniprot id: G4SZQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1091494:MEALZ RS00020
gene id: 1091494:MEALZ_RS00020
uniprot id: G4STN6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1091494:MEALZ RS02080
gene id: 1091494:MEALZ_RS02080
uniprot id: G4SYC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS10585
gene id: 1091494:MEALZ_RS10585
uniprot id: G4ST96
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1091494:MEALZ RS06655
gene id: 1091494:MEALZ_RS06655
uniprot id: G4SWZ8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1091494:MEALZ RS20980
gene id: 1091494:MEALZ_RS20980
uniprot id: G4T2F6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09240
gene id: 1091494:MEALZ_RS09240
uniprot id: G4T2C9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1091494:MEALZ RS05705
gene id: 1091494:MEALZ_RS05705
uniprot id: G4SUN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS11405
gene id: 1091494:MEALZ_RS11405
uniprot id: G4SUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS12120
gene id: 1091494:MEALZ_RS12120
uniprot id: G4SWE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS07870
gene id: 1091494:MEALZ_RS07870
uniprot id: G4SZG5
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16360
gene id: 1091494:MEALZ_RS16360
uniprot id: G4STL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1091494:MEALZ RS11510
gene id: 1091494:MEALZ_RS11510
uniprot id: G4SUW8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS17905
gene id: 1091494:MEALZ_RS17905
uniprot id: G4SXE6
names: Similarity
messages: Belongs to the MEMO1 family.

1091494:MEALZ RS16090
gene id: 1091494:MEALZ_RS16090
uniprot id: G4T4F1
names: Similarity
messages: Belongs to the peptidase M24B family.

1091494:MEALZ RS17555
gene id: 1091494:MEALZ_RS17555
uniprot id: G4SWL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1091494:MEALZ RS12285
gene id: 1091494:MEALZ_RS12285
uniprot id: G4SWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1091494:MEALZ RS01550
gene id: 1091494:MEALZ_RS01550
uniprot id: G4SWV0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1091494:MEALZ RS17910
gene id: 1091494:MEALZ_RS17910
uniprot id: G4SXE7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1091494:MEALZ RS16175
gene id: 1091494:MEALZ_RS16175
uniprot id: G4STH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1091494:MEALZ RS09980
gene id: 1091494:MEALZ_RS09980
uniprot id: G4T3J6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1091494:MEALZ RS17560
gene id: 1091494:MEALZ_RS17560
uniprot id: G4SWL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1091494:MEALZ RS17810
gene id: 1091494:MEALZ_RS17810
uniprot id: G4SXC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1091494:MEALZ RS16155
gene id: 1091494:MEALZ_RS16155
uniprot id: G4STH4
names: Similarity
messages: Belongs to the alphaproteobacteria porin family.

1091494:MEALZ RS04835
gene id: 1091494:MEALZ_RS04835
uniprot id: G4T3Y7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1091494:MEALZ RS01640
gene id: 1091494:MEALZ_RS01640
uniprot id: G4SWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1091494:MEALZ RS20960
gene id: 1091494:MEALZ_RS20960
uniprot id: G4T064
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS19455
gene id: 1091494:MEALZ_RS19455
uniprot id: G4T0L5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1091494:MEALZ RS16225
gene id: 1091494:MEALZ_RS16225
uniprot id: G4STI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1091494:MEALZ RS02245
gene id: 1091494:MEALZ_RS02245
uniprot id: G4SYF5
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS11950
gene id: 1091494:MEALZ_RS11950
uniprot id: G4SVR5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS01435
gene id: 1091494:MEALZ_RS01435
uniprot id: G4SWS6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS19080
gene id: 1091494:MEALZ_RS19080
uniprot id: G4SZU2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1091494:MEALZ RS08150
gene id: 1091494:MEALZ_RS08150
uniprot id: G4T070
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Belongs to the photoactive yellow protein family.

1091494:MEALZ RS06625
gene id: 1091494:MEALZ_RS06625
uniprot id: G4SWZ1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1091494:MEALZ RS19680
gene id: 1091494:MEALZ_RS19680
uniprot id: G4T1B4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1091494:MEALZ RS15390
gene id: 1091494:MEALZ_RS15390
uniprot id: G4T386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS08295
gene id: 1091494:MEALZ_RS08295
uniprot id: G4T0V5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS17675
gene id: 1091494:MEALZ_RS17675
uniprot id: G4SWN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1091494:MEALZ RS01905
gene id: 1091494:MEALZ_RS01905
uniprot id: G4SXN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1091494:MEALZ RS08815
gene id: 1091494:MEALZ_RS08815
uniprot id: G4T1Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1091494:MEALZ RS14385
gene id: 1091494:MEALZ_RS14385
uniprot id: G4T187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS20115
gene id: 1091494:MEALZ_RS20115
uniprot id: G4T4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1091494:MEALZ RS18405
gene id: 1091494:MEALZ_RS18405
uniprot id: G4SY99
names: Similarity
messages: Belongs to the peptidase S16 family.

1091494:MEALZ RS12290
gene id: 1091494:MEALZ_RS12290
uniprot id: G4SWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1091494:MEALZ RS09000
gene id: 1091494:MEALZ_RS09000
uniprot id: G4T1U0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1091494:MEALZ RS02350
gene id: 1091494:MEALZ_RS02350
uniprot id: G4SYH5
names: Similarity
messages: Belongs to the bacterial secretin family.

1091494:MEALZ RS15845
gene id: 1091494:MEALZ_RS15845
uniprot id: G4T4A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1091494:MEALZ RS20405
gene id: 1091494:MEALZ_RS20405
uniprot id: G4T4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26C family.
messages: Periplasm

1091494:MEALZ RS00695
gene id: 1091494:MEALZ_RS00695
uniprot id: G4SUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1091494:MEALZ RS13995
gene id: 1091494:MEALZ_RS13995
uniprot id: G4T0F0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1091494:MEALZ RS16640
gene id: 1091494:MEALZ_RS16640
uniprot id: G4SUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1091494:MEALZ RS17625
gene id: 1091494:MEALZ_RS17625
uniprot id: G4SWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1091494:MEALZ RS07415
gene id: 1091494:MEALZ_RS07415
uniprot id: G4SYM2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1091494:MEALZ RS14895
gene id: 1091494:MEALZ_RS14895
uniprot id: G4T2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1091494:MEALZ RS11025
gene id: 1091494:MEALZ_RS11025
uniprot id: G4SU25
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1091494:MEALZ RS00795
gene id: 1091494:MEALZ_RS00795
uniprot id: G4SV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1091494:MEALZ RS07705
gene id: 1091494:MEALZ_RS07705
uniprot id: G4SZD0
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1091494:MEALZ RS02460
gene id: 1091494:MEALZ_RS02460
uniprot id: G4SZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1091494:MEALZ RS15090
gene id: 1091494:MEALZ_RS15090
uniprot id: G4T2M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1091494:MEALZ RS02790
gene id: 1091494:MEALZ_RS02790
uniprot id: G4SZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1091494:MEALZ RS08790
gene id: 1091494:MEALZ_RS08790
uniprot id: G4T1P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS07985
gene id: 1091494:MEALZ_RS07985
uniprot id: G4T035
names: Subcellular Location Annotation
messages: Cell inner membrane

1091494:MEALZ RS11640
gene id: 1091494:MEALZ_RS11640
uniprot id: G4SUZ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1091494:MEALZ RS12200
gene id: 1091494:MEALZ_RS12200
uniprot id: G4SWF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1091494:MEALZ RS09765
gene id: 1091494:MEALZ_RS09765
uniprot id: G4T3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1091494:MEALZ RS18950
gene id: 1091494:MEALZ_RS18950
uniprot id: G4SZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1091494:MEALZ RS01065
gene id: 1091494:MEALZ_RS01065
uniprot id: G4SVZ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1091494:MEALZ RS05080
gene id: 1091494:MEALZ_RS05080
uniprot id: G4ST25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1091494:MEALZ RS18650
gene id: 1091494:MEALZ_RS18650
uniprot id: G4SZ04
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1091494:MEALZ RS07390
gene id: 1091494:MEALZ_RS07390
uniprot id: G4SYL7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1091494:MEALZ RS02255
gene id: 1091494:MEALZ_RS02255
uniprot id: G4SYF7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1091494:MEALZ RS00760
gene id: 1091494:MEALZ_RS00760
uniprot id: G4SV73
names: Similarity
messages: Belongs to the TrpC family.

1091494:MEALZ RS15265
gene id: 1091494:MEALZ_RS15265
uniprot id: G4T348
names: Similarity
messages: Belongs to the skp family.

1091494:MEALZ RS09210
gene id: 1091494:MEALZ_RS09210
uniprot id: G4T2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1091494:MEALZ RS02070
gene id: 1091494:MEALZ_RS02070
uniprot id: G4SXR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS17685
gene id: 1091494:MEALZ_RS17685
uniprot id: G4SWN9
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1091494:MEALZ RS01125
gene id: 1091494:MEALZ_RS01125
uniprot id: G4SW06
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS04395
gene id: 1091494:MEALZ_RS04395
uniprot id: G4T3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1091494:MEALZ RS05315
gene id: 1091494:MEALZ_RS05315
uniprot id: G4STW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1091494:MEALZ RS15640
gene id: 1091494:MEALZ_RS15640
uniprot id: G4T3R3
names: Subcellular Location Annotation
messages: Cytoplasm

1091494:MEALZ RS06140
gene id: 1091494:MEALZ_RS06140
uniprot id: G4SVH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1091494:MEALZ RS03125
gene id: 1091494:MEALZ_RS03125
uniprot id: G4T0Q8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS05555
gene id: 1091494:MEALZ_RS05555
uniprot id: G4SU08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1091494:MEALZ RS13035
gene id: 1091494:MEALZ_RS13035
uniprot id: G4SY47
names: Similarity
messages: Belongs to the GppA/Ppx family.

1091494:MEALZ RS04455
gene id: 1091494:MEALZ_RS04455
uniprot id: G4T3C2
names: Similarity
messages: Belongs to the hemerythrin family.

1091494:MEALZ RS08685
gene id: 1091494:MEALZ_RS08685
uniprot id: G4T1N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1091494:MEALZ RS05120
gene id: 1091494:MEALZ_RS05120
uniprot id: G4ST32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

1091494:MEALZ RS14000
gene id: 1091494:MEALZ_RS14000
uniprot id: G4T0F1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1091494:MEALZ RS09860
gene id: 1091494:MEALZ_RS09860
uniprot id: G4T3H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1091494:MEALZ RS09645
gene id: 1091494:MEALZ_RS09645
uniprot id: G4T2Z3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1091494:MEALZ RS16370
gene id: 1091494:MEALZ_RS16370
uniprot id: G4STL8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1091494:MEALZ RS12800
gene id: 1091494:MEALZ_RS12800
uniprot id: G4SXZ6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1091494:MEALZ RS00080
gene id: 1091494:MEALZ_RS00080
uniprot id: G4STP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1091494:MEALZ RS03115
gene id: 1091494:MEALZ_RS03115
uniprot id: G4T0Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1091494:MEALZ RS04015
gene id: 1091494:MEALZ_RS04015
uniprot id: G4T2P0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1091494:MEALZ RS13080
gene id: 1091494:MEALZ_RS13080
uniprot id: G4SYQ7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1091494:MEALZ RS18075
gene id: 1091494:MEALZ_RS18075
uniprot id: G4SXH9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS03700
gene id: 1091494:MEALZ_RS03700
uniprot id: G4T234
names: Similarity
messages: Belongs to the AOR/FOR family.

1091494:MEALZ RS11775
gene id: 1091494:MEALZ_RS11775
uniprot id: G4SVM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1091494:MEALZ RS06190
gene id: 1091494:MEALZ_RS06190
uniprot id: G4SVI7
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1091494:MEALZ RS17460
gene id: 1091494:MEALZ_RS17460
uniprot id: G4SVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1091494:MEALZ RS14010
gene id: 1091494:MEALZ_RS14010
uniprot id: G4T0F3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1091494:MEALZ RS15865
gene id: 1091494:MEALZ_RS15865
uniprot id: Q4JQJ5
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
messages: Homodimer.
messages: Inhibited by zinc and cadmium.

1091494:MEALZ RS13785
gene id: 1091494:MEALZ_RS13785
uniprot id: G4T0B2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1091494:MEALZ RS13015
gene id: 1091494:MEALZ_RS13015
uniprot id: G4SY39
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS15535
gene id: 1091494:MEALZ_RS15535
uniprot id: G4T3P2
names: Similarity
messages: Belongs to the peptidase A24 family.

1091494:MEALZ RS16745
gene id: 1091494:MEALZ_RS16745
uniprot id: G4SUD6
names: Similarity
messages: Belongs to the YjdM family.

1091494:MEALZ RS04285
gene id: 1091494:MEALZ_RS04285
uniprot id: G4T390
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS01950
gene id: 1091494:MEALZ_RS01950
uniprot id: G4SXN9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1091494:MEALZ RS07340
gene id: 1091494:MEALZ_RS07340
uniprot id: G4SYK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1091494:MEALZ RS10225
gene id: 1091494:MEALZ_RS10225
uniprot id: G4T437
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS09975
gene id: 1091494:MEALZ_RS09975
uniprot id: G4T3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1091494:MEALZ RS16685
gene id: 1091494:MEALZ_RS16685
uniprot id: G4SUC3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1091494:MEALZ RS00005
gene id: 1091494:MEALZ_RS00005
uniprot id: G4STN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1091494:MEALZ RS02700
gene id: 1091494:MEALZ_RS02700
uniprot id: G4SZA0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1091494:MEALZ RS06450
gene id: 1091494:MEALZ_RS06450
uniprot id: G4SW97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1091494:MEALZ RS00100
gene id: 1091494:MEALZ_RS00100
uniprot id: G4STQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1091494:MEALZ RS04905
gene id: 1091494:MEALZ_RS04905
uniprot id: G4T401
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1091494:MEALZ RS14900
gene id: 1091494:MEALZ_RS14900
uniprot id: G4T2I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1091494:MEALZ RS03020
gene id: 1091494:MEALZ_RS03020
uniprot id: G4T0N6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1091494:MEALZ RS11755
gene id: 1091494:MEALZ_RS11755
uniprot id: G4SVM4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1091494:MEALZ RS14425
gene id: 1091494:MEALZ_RS14425
uniprot id: G4T1V2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19035
gene id: 1091494:MEALZ_RS19035
uniprot id: G4SZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1091494:MEALZ RS16120
gene id: 1091494:MEALZ_RS16120
uniprot id: G4STH0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1091494:MEALZ RS03995
gene id: 1091494:MEALZ_RS03995
uniprot id: G4T2N6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09835
gene id: 1091494:MEALZ_RS09835
uniprot id: G4T3G5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1091494:MEALZ RS11805
gene id: 1091494:MEALZ_RS11805
uniprot id: G4SVN5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS18855
gene id: 1091494:MEALZ_RS18855
uniprot id: G4SZQ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1091494:MEALZ RS01530
gene id: 1091494:MEALZ_RS01530
uniprot id: G4SWU6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS19800
gene id: 1091494:MEALZ_RS19800
uniprot id: G4T1E0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1091494:MEALZ RS13825
gene id: 1091494:MEALZ_RS13825
uniprot id: G4T0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1091494:MEALZ RS07080
gene id: 1091494:MEALZ_RS07080
uniprot id: G4SXU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1091494:MEALZ RS19030
gene id: 1091494:MEALZ_RS19030
uniprot id: G4SZT2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1091494:MEALZ RS01250
gene id: 1091494:MEALZ_RS01250
uniprot id: G4SW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1091494:MEALZ RS20600
gene id: 1091494:MEALZ_RS20600
uniprot id: G4T2S9
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS09135
gene id: 1091494:MEALZ_RS09135
uniprot id: G4T2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS10080
gene id: 1091494:MEALZ_RS10080
uniprot id: G4T3L2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1091494:MEALZ RS08335
gene id: 1091494:MEALZ_RS08335
uniprot id: G4T0W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1091494:MEALZ RS15835
gene id: 1091494:MEALZ_RS15835
uniprot id: G4T498
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1091494:MEALZ RS03430
gene id: 1091494:MEALZ_RS03430
uniprot id: G4T1I1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1091494:MEALZ RS20080
gene id: 1091494:MEALZ_RS20080
uniprot id: G4T4I4
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS00485
gene id: 1091494:MEALZ_RS00485
uniprot id: G4SUH3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1091494:MEALZ RS19370
gene id: 1091494:MEALZ_RS19370
uniprot id: G4T0J9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1091494:MEALZ RS07610
gene id: 1091494:MEALZ_RS07610
uniprot id: G4SZB1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1091494:MEALZ RS06225
gene id: 1091494:MEALZ_RS06225
uniprot id: G4SVJ4
names: Similarity
messages: Belongs to the PhzF family.

1091494:MEALZ RS18350
gene id: 1091494:MEALZ_RS18350
uniprot id: G4SY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1091494:MEALZ RS05925
gene id: 1091494:MEALZ_RS05925
uniprot id: G4SVD4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1091494:MEALZ RS23550
gene id: 1091494:MEALZ_RS23550
uniprot id: G4T0K4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1091494:MEALZ RS01220
gene id: 1091494:MEALZ_RS01220
uniprot id: G4SW27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1091494:MEALZ RS00460
gene id: 1091494:MEALZ_RS00460
uniprot id: G4SUG9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1091494:MEALZ RS08950
gene id: 1091494:MEALZ_RS08950
uniprot id: G4T1T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1091494:MEALZ RS13915
gene id: 1091494:MEALZ_RS13915
uniprot id: G4T0D5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS17630
gene id: 1091494:MEALZ_RS17630
uniprot id: G4SWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

1091494:MEALZ RS19600
gene id: 1091494:MEALZ_RS19600
uniprot id: G4T197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS19705
gene id: 1091494:MEALZ_RS19705
uniprot id: G4T1B9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1091494:MEALZ RS14835
gene id: 1091494:MEALZ_RS14835
uniprot id: G4T2H5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS11770
gene id: 1091494:MEALZ_RS11770
uniprot id: G4SVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1091494:MEALZ RS00385
gene id: 1091494:MEALZ_RS00385
uniprot id: G4SUF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1091494:MEALZ RS04875
gene id: 1091494:MEALZ_RS04875
uniprot id: G4T3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1091494:MEALZ RS12580
gene id: 1091494:MEALZ_RS12580
uniprot id: G4SX91
names: Similarity
messages: Belongs to the XFP family.

1091494:MEALZ RS08225
gene id: 1091494:MEALZ_RS08225
uniprot id: G4T086
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1091494:MEALZ RS13520
gene id: 1091494:MEALZ_RS13520
uniprot id: G4SZK6
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS15670
gene id: 1091494:MEALZ_RS15670
uniprot id: G4T3S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1091494:MEALZ RS18265
gene id: 1091494:MEALZ_RS18265
uniprot id: G4SY71
names: Similarity
messages: Belongs to the peptidase A31 family.

1091494:MEALZ RS12750
gene id: 1091494:MEALZ_RS12750
uniprot id: G4SXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1091494:MEALZ RS17545
gene id: 1091494:MEALZ_RS17545
uniprot id: G4SWL2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1091494:MEALZ RS04650
gene id: 1091494:MEALZ_RS04650
uniprot id: G4T3V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

1091494:MEALZ RS17570
gene id: 1091494:MEALZ_RS17570
uniprot id: G4SWL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1091494:MEALZ RS02085
gene id: 1091494:MEALZ_RS02085
uniprot id: G4SYC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1091494:MEALZ RS16365
gene id: 1091494:MEALZ_RS16365
uniprot id: G4STL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1091494:MEALZ RS20400
gene id: 1091494:MEALZ_RS20400
uniprot id: G4T4P7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1091494:MEALZ RS01110
gene id: 1091494:MEALZ_RS01110
uniprot id: G4SW03
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1091494:MEALZ RS11860
gene id: 1091494:MEALZ_RS11860
uniprot id: G4SVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1091494:MEALZ RS02840
gene id: 1091494:MEALZ_RS02840
uniprot id: G4SZY6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1091494:MEALZ RS08240
gene id: 1091494:MEALZ_RS08240
uniprot id: G4T089
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1091494:MEALZ RS08050
gene id: 1091494:MEALZ_RS08050
uniprot id: G4T049
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1091494:MEALZ RS09020
gene id: 1091494:MEALZ_RS09020
uniprot id: G4T1U4
names: Similarity
messages: Belongs to the YciI family.

1091494:MEALZ RS06680
gene id: 1091494:MEALZ_RS06680
uniprot id: G4SX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS04970
gene id: 1091494:MEALZ_RS04970
uniprot id: G4ST04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1091494:MEALZ RS05060
gene id: 1091494:MEALZ_RS05060
uniprot id: G4ST21
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1091494:MEALZ RS14205
gene id: 1091494:MEALZ_RS14205
uniprot id: G4T151
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1091494:MEALZ RS05940
gene id: 1091494:MEALZ_RS05940
uniprot id: G4SVD7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1091494:MEALZ RS07910
gene id: 1091494:MEALZ_RS07910
uniprot id: G4SZH0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1091494:MEALZ RS15440
gene id: 1091494:MEALZ_RS15440
uniprot id: G4T383
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1091494:MEALZ RS02260
gene id: 1091494:MEALZ_RS02260
uniprot id: G4SYF8
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS16880
gene id: 1091494:MEALZ_RS16880
uniprot id: G4SV13
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1091494:MEALZ RS13845
gene id: 1091494:MEALZ_RS13845
uniprot id: G4T0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1091494:MEALZ RS14435
gene id: 1091494:MEALZ_RS14435
uniprot id: G4T1V4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1091494:MEALZ RS01150
gene id: 1091494:MEALZ_RS01150
uniprot id: G4SW12
names: Similarity
messages: Belongs to the UPF0111 family.

1091494:MEALZ RS00670
gene id: 1091494:MEALZ_RS00670
uniprot id: G4SUK3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1091494:MEALZ RS17165
gene id: 1091494:MEALZ_RS17165
uniprot id: G4SVT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1091494:MEALZ RS04020
gene id: 1091494:MEALZ_RS04020
uniprot id: G4T2P1
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1091494:MEALZ RS12885
gene id: 1091494:MEALZ_RS12885
uniprot id: G4SY14
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1091494:MEALZ RS12655
gene id: 1091494:MEALZ_RS12655
uniprot id: G4SXA9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1091494:MEALZ RS13990
gene id: 1091494:MEALZ_RS13990
uniprot id: G4T0E9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1091494:MEALZ RS03305
gene id: 1091494:MEALZ_RS03305
uniprot id: G4T0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1091494:MEALZ RS12405
gene id: 1091494:MEALZ_RS12405
uniprot id: G4SWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1091494:MEALZ RS08990
gene id: 1091494:MEALZ_RS08990
uniprot id: G4T1T8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1091494:MEALZ RS18110
gene id: 1091494:MEALZ_RS18110
uniprot id: G4SXI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1091494:MEALZ RS20640
gene id: 1091494:MEALZ_RS20640
uniprot id: G4SVG5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS14860
gene id: 1091494:MEALZ_RS14860
uniprot id: G4T2I0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1091494:MEALZ RS12190
gene id: 1091494:MEALZ_RS12190
uniprot id: G4SWF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1091494:MEALZ RS14495
gene id: 1091494:MEALZ_RS14495
uniprot id: G4T1W6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1091494:MEALZ RS16950
gene id: 1091494:MEALZ_RS16950
uniprot id: G4SV27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1091494:MEALZ RS01075
gene id: 1091494:MEALZ_RS01075
uniprot id: G4SVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1091494:MEALZ RS15625
gene id: 1091494:MEALZ_RS15625
uniprot id: G4T3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1091494:MEALZ RS03095
gene id: 1091494:MEALZ_RS03095
uniprot id: G4T0Q2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1091494:MEALZ RS06645
gene id: 1091494:MEALZ_RS06645
uniprot id: G4SWZ6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1091494:MEALZ RS17695
gene id: 1091494:MEALZ_RS17695
uniprot id: G4SWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1091494:MEALZ RS15610
gene id: 1091494:MEALZ_RS15610
uniprot id: G4T3Q7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1091494:MEALZ RS15885
gene id: 1091494:MEALZ_RS15885
uniprot id: G4T4A8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1091494:MEALZ RS02925
gene id: 1091494:MEALZ_RS02925
uniprot id: G4T006
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1091494:MEALZ RS18445
gene id: 1091494:MEALZ_RS18445
uniprot id: G4SYA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1091494:MEALZ RS13005
gene id: 1091494:MEALZ_RS13005
uniprot id: G4SY37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1091494:MEALZ RS12905
gene id: 1091494:MEALZ_RS12905
uniprot id: G4SY18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1091494:MEALZ RS09945
gene id: 1091494:MEALZ_RS09945
uniprot id: G4T3I8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1091494:MEALZ RS16330
gene id: 1091494:MEALZ_RS16330
uniprot id: G4STL0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1091494:MEALZ RS01855
gene id: 1091494:MEALZ_RS01855
uniprot id: G4SXM1
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1091494:MEALZ RS13675
gene id: 1091494:MEALZ_RS13675
uniprot id: G4SZP4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS14600
gene id: 1091494:MEALZ_RS14600
uniprot id: G4T1Y7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1091494:MEALZ RS10880
gene id: 1091494:MEALZ_RS10880
uniprot id: G4STE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1091494:MEALZ RS17395
gene id: 1091494:MEALZ_RS17395
uniprot id: G4SVX1
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

1091494:MEALZ RS04130
gene id: 1091494:MEALZ_RS04130
uniprot id: G4T2R7
names: Similarity
messages: Belongs to the P(II) protein family.

1091494:MEALZ RS12845
gene id: 1091494:MEALZ_RS12845
uniprot id: G4SY05
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1091494:MEALZ RS00685
gene id: 1091494:MEALZ_RS00685
uniprot id: G4SUK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1091494:MEALZ RS19635
gene id: 1091494:MEALZ_RS19635
uniprot id: G4T1A5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1091494:MEALZ RS13840
gene id: 1091494:MEALZ_RS13840
uniprot id: G4T0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1091494:MEALZ RS09380
gene id: 1091494:MEALZ_RS09380
uniprot id: G4T2F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS08675
gene id: 1091494:MEALZ_RS08675
uniprot id: G4T1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1091494:MEALZ RS10865
gene id: 1091494:MEALZ_RS10865
uniprot id: G4STE5
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00375
gene id: 1091494:MEALZ_RS00375
uniprot id: G4SUF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1091494:MEALZ RS04240
gene id: 1091494:MEALZ_RS04240
uniprot id: G4T2T9
names: Similarity
messages: Belongs to the PhoH family.

1091494:MEALZ RS07060
gene id: 1091494:MEALZ_RS07060
uniprot id: G4SXU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS01620
gene id: 1091494:MEALZ_RS01620
uniprot id: G4SWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1091494:MEALZ RS07930
gene id: 1091494:MEALZ_RS07930
uniprot id: G4SZH4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1091494:MEALZ RS09655
gene id: 1091494:MEALZ_RS09655
uniprot id: G4T2Z5
names: Similarity
messages: Belongs to the HupF/HypC family.

1091494:MEALZ RS17015
gene id: 1091494:MEALZ_RS17015
uniprot id: G4SV41
names: Similarity
messages: Belongs to the peptidase U62 family.

1091494:MEALZ RS04035
gene id: 1091494:MEALZ_RS04035
uniprot id: G4T2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1091494:MEALZ RS15600
gene id: 1091494:MEALZ_RS15600
uniprot id: G4T3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS09650
gene id: 1091494:MEALZ_RS09650
uniprot id: G4T2Z4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1091494:MEALZ RS09430
gene id: 1091494:MEALZ_RS09430
uniprot id: G4T2V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS14955
gene id: 1091494:MEALZ_RS14955
uniprot id: G4T2J7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1091494:MEALZ RS16055
gene id: 1091494:MEALZ_RS16055
uniprot id: G4T4E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1091494:MEALZ RS06460
gene id: 1091494:MEALZ_RS06460
uniprot id: G4SW99
names: Similarity
messages: Belongs to the CopC family.

1091494:MEALZ RS02765
gene id: 1091494:MEALZ_RS02765
uniprot id: G4SZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1091494:MEALZ RS13470
gene id: 1091494:MEALZ_RS13470
uniprot id: G4SZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1091494:MEALZ RS05920
gene id: 1091494:MEALZ_RS05920
uniprot id: G4SUS8
names: Similarity
messages: Belongs to the peptidase S13 family.

1091494:MEALZ RS11360
gene id: 1091494:MEALZ_RS11360
uniprot id: G4SUU0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1091494:MEALZ RS13500
gene id: 1091494:MEALZ_RS13500
uniprot id: G4SZK2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1091494:MEALZ RS18275
gene id: 1091494:MEALZ_RS18275
uniprot id: G4SY73
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1091494:MEALZ RS07100
gene id: 1091494:MEALZ_RS07100
uniprot id: G4SXU9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS19685
gene id: 1091494:MEALZ_RS19685
uniprot id: G4T1B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1091494:MEALZ RS19465
gene id: 1091494:MEALZ_RS19465
uniprot id: G4T0L7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1091494:MEALZ RS17575
gene id: 1091494:MEALZ_RS17575
uniprot id: G4SWL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1091494:MEALZ RS02330
gene id: 1091494:MEALZ_RS02330
uniprot id: G4SYH2
names: Similarity
messages: Belongs to the GSP E family.

1091494:MEALZ RS16985
gene id: 1091494:MEALZ_RS16985
uniprot id: G4SV34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1091494:MEALZ RS08160
gene id: 1091494:MEALZ_RS08160
uniprot id: G4T073
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1091494:MEALZ RS09405
gene id: 1091494:MEALZ_RS09405
uniprot id: G4T2U7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1091494:MEALZ RS01845
gene id: 1091494:MEALZ_RS01845
uniprot id: G4SXL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1091494:MEALZ RS18360
gene id: 1091494:MEALZ_RS18360
uniprot id: G4SY90
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1091494:MEALZ RS07885
gene id: 1091494:MEALZ_RS07885
uniprot id: G4SZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1091494:MEALZ RS02060
gene id: 1091494:MEALZ_RS02060
uniprot id: G4SXR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1091494:MEALZ RS06000
gene id: 1091494:MEALZ_RS06000
uniprot id: G4SVE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1091494:MEALZ RS03665
gene id: 1091494:MEALZ_RS03665
uniprot id: G4T227
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1091494:MEALZ RS01955
gene id: 1091494:MEALZ_RS01955
uniprot id: G4SXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1091494:MEALZ RS15110
gene id: 1091494:MEALZ_RS15110
uniprot id: G4T2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1091494:MEALZ RS18720
gene id: 1091494:MEALZ_RS18720
uniprot id: G4SZ17
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1091494:MEALZ RS10680
gene id: 1091494:MEALZ_RS10680
uniprot id: G4STB3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1091494:MEALZ RS02845
gene id: 1091494:MEALZ_RS02845
uniprot id: G4SZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1091494:MEALZ RS17490
gene id: 1091494:MEALZ_RS17490
uniprot id: G4SWK1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1091494:MEALZ RS11400
gene id: 1091494:MEALZ_RS11400
uniprot id: G4SUU8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1091494:MEALZ RS05235
gene id: 1091494:MEALZ_RS05235
uniprot id: G4ST56
names: Similarity
messages: Belongs to the peptidase S24 family.

1091494:MEALZ RS16645
gene id: 1091494:MEALZ_RS16645
uniprot id: G4SUB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1091494:MEALZ RS03165
gene id: 1091494:MEALZ_RS03165
uniprot id: G4T0R6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1091494:MEALZ RS09950
gene id: 1091494:MEALZ_RS09950
uniprot id: G4T3I9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1091494:MEALZ RS09995
gene id: 1091494:MEALZ_RS09995
uniprot id: G4T3J9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1091494:MEALZ RS12995
gene id: 1091494:MEALZ_RS12995
uniprot id: G4SY35
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1091494:MEALZ RS04855
gene id: 1091494:MEALZ_RS04855
uniprot id: G4T3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1091494:MEALZ RS03715
gene id: 1091494:MEALZ_RS03715
uniprot id: G4T237
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1091494:MEALZ RS07580
gene id: 1091494:MEALZ_RS07580
uniprot id: G4SZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1091494:MEALZ RS16485
gene id: 1091494:MEALZ_RS16485
uniprot id: G4SU85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1091494:MEALZ RS12175
gene id: 1091494:MEALZ_RS12175
uniprot id: G4SWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1091494:MEALZ RS12085
gene id: 1091494:MEALZ_RS12085
uniprot id: G4SWD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1091494:MEALZ RS06630
gene id: 1091494:MEALZ_RS06630
uniprot id: G4SWZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1091494:MEALZ RS19505
gene id: 1091494:MEALZ_RS19505
uniprot id: G4T0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1091494:MEALZ RS03300
gene id: 1091494:MEALZ_RS03300
uniprot id: G4T0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1091494:MEALZ RS11230
gene id: 1091494:MEALZ_RS11230
uniprot id: G4SU69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1091494:MEALZ RS06040
gene id: 1091494:MEALZ_RS06040
uniprot id: G4SVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1091494:MEALZ RS02890
gene id: 1091494:MEALZ_RS02890
uniprot id: G4SZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1091494:MEALZ RS04810
gene id: 1091494:MEALZ_RS04810
uniprot id: G4T3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1091494:MEALZ RS14320
gene id: 1091494:MEALZ_RS14320
uniprot id: G4T174
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1091494:MEALZ RS16815
gene id: 1091494:MEALZ_RS16815
uniprot id: G4SUE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1091494:MEALZ RS05595
gene id: 1091494:MEALZ_RS05595
uniprot id: G4SU13
names: Subcellular Location Annotation
messages: Membrane

1091494:MEALZ RS00380
gene id: 1091494:MEALZ_RS00380
uniprot id: G4SUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1091494:MEALZ RS01085
gene id: 1091494:MEALZ_RS01085
uniprot id: G4SVZ8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1091494:MEALZ RS11015
gene id: 1091494:MEALZ_RS11015
uniprot id: G4SU23
names: Similarity
messages: Belongs to the YkuD family.

1091494:MEALZ RS11485
gene id: 1091494:MEALZ_RS11485
uniprot id: G4SUW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1091494:MEALZ RS03990
gene id: 1091494:MEALZ_RS03990
uniprot id: G4T2N5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.