1085644:E3E15 RS02505
gene id: 1085644:E3E15_RS02505
uniprot id: A0A6M3HT06
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1085644:E3E15 RS05120
gene id: 1085644:E3E15_RS05120
uniprot id: A0A6M3HU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1085644:E3E15 RS07000
gene id: 1085644:E3E15_RS07000
uniprot id: A0A6M3HY89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1085644:E3E15 RS00865
gene id: 1085644:E3E15_RS00865
uniprot id: A0A6M3HRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1085644:E3E15 RS04655
gene id: 1085644:E3E15_RS04655
uniprot id: A0A6M3HVN3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1085644:E3E15 RS06630
gene id: 1085644:E3E15_RS06630
uniprot id: A0A6M3HV09
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS04175
gene id: 1085644:E3E15_RS04175
uniprot id: A0A6M3HTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1085644:E3E15 RS03565
gene id: 1085644:E3E15_RS03565
uniprot id: A0A6M3HTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1085644:E3E15 RS06455
gene id: 1085644:E3E15_RS06455
uniprot id: A0A6M3HUW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1085644:E3E15 RS05115
gene id: 1085644:E3E15_RS05115
uniprot id: A0A6M3HWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1085644:E3E15 RS03360
gene id: 1085644:E3E15_RS03360
uniprot id: A0A6M3HTC8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1085644:E3E15 RS06685
gene id: 1085644:E3E15_RS06685
uniprot id: A0A6M3HV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1085644:E3E15 RS04215
gene id: 1085644:E3E15_RS04215
uniprot id: A0A6M3HU27
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1085644:E3E15 RS05070
gene id: 1085644:E3E15_RS05070
uniprot id: A0A6M3HU50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1085644:E3E15 RS05090
gene id: 1085644:E3E15_RS05090
uniprot id: A0A6M3HU53
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1085644:E3E15 RS07020
gene id: 1085644:E3E15_RS07020
uniprot id: A0A6M3HV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1085644:E3E15 RS07770
gene id: 1085644:E3E15_RS07770
uniprot id: A0A6M3HVE2
names: Similarity
messages: Belongs to the universal stress protein A family.

1085644:E3E15 RS02425
gene id: 1085644:E3E15_RS02425
uniprot id: A0A6M3HSX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1085644:E3E15 RS00455
gene id: 1085644:E3E15_RS00455
uniprot id: A0A6M3HS04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1085644:E3E15 RS05515
gene id: 1085644:E3E15_RS05515
uniprot id: A0A6M3HUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1085644:E3E15 RS02950
gene id: 1085644:E3E15_RS02950
uniprot id: A0A6M3HT73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1085644:E3E15 RS03090
gene id: 1085644:E3E15_RS03090
uniprot id: A0A6M3HTM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1085644:E3E15 RS05530
gene id: 1085644:E3E15_RS05530
uniprot id: A0A6M3HUA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1085644:E3E15 RS02175
gene id: 1085644:E3E15_RS02175
uniprot id: A0A6M3HVZ5
names: Similarity
messages: Belongs to the FeoA family.

1085644:E3E15 RS02650
gene id: 1085644:E3E15_RS02650
uniprot id: A0A6M3HT02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1085644:E3E15 RS02375
gene id: 1085644:E3E15_RS02375
uniprot id: A0A6M3HSW6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1085644:E3E15 RS07500
gene id: 1085644:E3E15_RS07500
uniprot id: A0A6M3HVF3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1085644:E3E15 RS01785
gene id: 1085644:E3E15_RS01785
uniprot id: A0A6M3HST7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1085644:E3E15 RS07665
gene id: 1085644:E3E15_RS07665
uniprot id: A0A6M3HVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS03120
gene id: 1085644:E3E15_RS03120
uniprot id: A0A6M3HXN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1085644:E3E15 RS05435
gene id: 1085644:E3E15_RS05435
uniprot id: A0A6M3HU99
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1085644:E3E15 RS01175
gene id: 1085644:E3E15_RS01175
uniprot id: A0A6M3HS19
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1085644:E3E15 RS03475
gene id: 1085644:E3E15_RS03475
uniprot id: A0A6M3HWP0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1085644:E3E15 RS02370
gene id: 1085644:E3E15_RS02370
uniprot id: A0A6M3HSM3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1085644:E3E15 RS00335
gene id: 1085644:E3E15_RS00335
uniprot id: A0A6M3HRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1085644:E3E15 RS00350
gene id: 1085644:E3E15_RS00350
uniprot id: A0A6M3HRY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS00955
gene id: 1085644:E3E15_RS00955
uniprot id: A0A6M3HSG1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1085644:E3E15 RS03020
gene id: 1085644:E3E15_RS03020
uniprot id: A0A6M3HTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085644:E3E15 RS01870
gene id: 1085644:E3E15_RS01870
uniprot id: A0A6M3HWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1085644:E3E15 RS02610
gene id: 1085644:E3E15_RS02610
uniprot id: A0A6M3HTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1085644:E3E15 RS06545
gene id: 1085644:E3E15_RS06545
uniprot id: A0A6M3HV20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085644:E3E15 RS01900
gene id: 1085644:E3E15_RS01900
uniprot id: A0A6M3HVU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1085644:E3E15 RS04440
gene id: 1085644:E3E15_RS04440
uniprot id: A0A6M3HU84
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1085644:E3E15 RS06445
gene id: 1085644:E3E15_RS06445
uniprot id: A0A6M3HXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1085644:E3E15 RS06945
gene id: 1085644:E3E15_RS06945
uniprot id: A0A6M3HVD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1085644:E3E15 RS06940
gene id: 1085644:E3E15_RS06940
uniprot id: A0A6M3HV04
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1085644:E3E15 RS00975
gene id: 1085644:E3E15_RS00975
uniprot id: A0A6M3HRW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1085644:E3E15 RS04865
gene id: 1085644:E3E15_RS04865
uniprot id: A0A6M3HX80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1085644:E3E15 RS00985
gene id: 1085644:E3E15_RS00985
uniprot id: A0A6M3HW76
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1085644:E3E15 RS07555
gene id: 1085644:E3E15_RS07555
uniprot id: A0A6M3HVI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1085644:E3E15 RS06030
gene id: 1085644:E3E15_RS06030
uniprot id: A0A6M3HXT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1085644:E3E15 RS07270
gene id: 1085644:E3E15_RS07270
uniprot id: A0A6M3HV40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1085644:E3E15 RS06105
gene id: 1085644:E3E15_RS06105
uniprot id: A0A6M3HUJ3
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS04905
gene id: 1085644:E3E15_RS04905
uniprot id: A0A6M3HU80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1085644:E3E15 RS00480
gene id: 1085644:E3E15_RS00480
uniprot id: A0A6M3HUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1085644:E3E15 RS00840
gene id: 1085644:E3E15_RS00840
uniprot id: A0A6M3HS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1085644:E3E15 RS06440
gene id: 1085644:E3E15_RS06440
uniprot id: A0A6M3HXZ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1085644:E3E15 RS00310
gene id: 1085644:E3E15_RS00310
uniprot id: A0A6M3HRU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1085644:E3E15 RS00970
gene id: 1085644:E3E15_RS00970
uniprot id: A0A6M3HS69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1085644:E3E15 RS06920
gene id: 1085644:E3E15_RS06920
uniprot id: A0A6M3HV34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1085644:E3E15 RS00735
gene id: 1085644:E3E15_RS00735
uniprot id: A0A6M3HS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1085644:E3E15 RS05835
gene id: 1085644:E3E15_RS05835
uniprot id: A0A6M3HX87
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1085644:E3E15 RS05330
gene id: 1085644:E3E15_RS05330
uniprot id: A0A6M3HU68
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS01695
gene id: 1085644:E3E15_RS01695
uniprot id: A0A6M3HV97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1085644:E3E15 RS01530
gene id: 1085644:E3E15_RS01530
uniprot id: A0A6M3HVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1085644:E3E15 RS04020
gene id: 1085644:E3E15_RS04020
uniprot id: A0A6M3HTS5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1085644:E3E15 RS06925
gene id: 1085644:E3E15_RS06925
uniprot id: A0A6M3HZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1085644:E3E15 RS05495
gene id: 1085644:E3E15_RS05495
uniprot id: A0A6M3HUN9
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS05385
gene id: 1085644:E3E15_RS05385
uniprot id: A0A6M3HU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1085644:E3E15 RS03065
gene id: 1085644:E3E15_RS03065
uniprot id: A0A6M3HT90
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1085644:E3E15 RS06975
gene id: 1085644:E3E15_RS06975
uniprot id: A0A6M3HZK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1085644:E3E15 RS04280
gene id: 1085644:E3E15_RS04280
uniprot id: A0A6M3HTR8
names: Similarity
messages: Belongs to the UPF0250 family.

1085644:E3E15 RS04670
gene id: 1085644:E3E15_RS04670
uniprot id: A0A6M3HUB3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1085644:E3E15 RS05325
gene id: 1085644:E3E15_RS05325
uniprot id: A0A6M3HU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1085644:E3E15 RS01700
gene id: 1085644:E3E15_RS01700
uniprot id: A0A6M3HSI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1085644:E3E15 RS02735
gene id: 1085644:E3E15_RS02735
uniprot id: A0A6M3HVT9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1085644:E3E15 RS02515
gene id: 1085644:E3E15_RS02515
uniprot id: A0A6M3HW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1085644:E3E15 RS05215
gene id: 1085644:E3E15_RS05215
uniprot id: A0A6M3HWX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1085644:E3E15 RS01495
gene id: 1085644:E3E15_RS01495
uniprot id: A0A6M3HS52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1085644:E3E15 RS00835
gene id: 1085644:E3E15_RS00835
uniprot id: A0A6M3HRW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1085644:E3E15 RS07520
gene id: 1085644:E3E15_RS07520
uniprot id: A0A6M3HYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1085644:E3E15 RS07010
gene id: 1085644:E3E15_RS07010
uniprot id: A0A6M3HUZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1085644:E3E15 RS03925
gene id: 1085644:E3E15_RS03925
uniprot id: A0A6M3HWU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085644:E3E15 RS05210
gene id: 1085644:E3E15_RS05210
uniprot id: A0A6M3HXD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1085644:E3E15 RS06280
gene id: 1085644:E3E15_RS06280
uniprot id: A0A6M3HXW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1085644:E3E15 RS04915
gene id: 1085644:E3E15_RS04915
uniprot id: A0A6M3HX89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1085644:E3E15 RS00380
gene id: 1085644:E3E15_RS00380
uniprot id: A0A6M3HRY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1085644:E3E15 RS07560
gene id: 1085644:E3E15_RS07560
uniprot id: A0A6M3HVA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1085644:E3E15 RS02365
gene id: 1085644:E3E15_RS02365
uniprot id: A0A6M3HSU4
names: Subcellular Location Annotation
messages: Cytoplasm

1085644:E3E15 RS01265
gene id: 1085644:E3E15_RS01265
uniprot id: A0A6M3HSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1085644:E3E15 RS04830
gene id: 1085644:E3E15_RS04830
uniprot id: A0A6M3HTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1085644:E3E15 RS01640
gene id: 1085644:E3E15_RS01640
uniprot id: A0A6M3HSH7
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1085644:E3E15 RS00785
gene id: 1085644:E3E15_RS00785
uniprot id: A0A6M3HRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1085644:E3E15 RS03685
gene id: 1085644:E3E15_RS03685
uniprot id: A0A6M3HTZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085644:E3E15 RS06600
gene id: 1085644:E3E15_RS06600
uniprot id: A0A6M3HUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1085644:E3E15 RS06010
gene id: 1085644:E3E15_RS06010
uniprot id: A0A6M3HUV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1085644:E3E15 RS01630
gene id: 1085644:E3E15_RS01630
uniprot id: A0A6M3HVM7
names: Similarity
messages: Belongs to the thioredoxin family.

1085644:E3E15 RS06935
gene id: 1085644:E3E15_RS06935
uniprot id: A0A6M3HV49
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1085644:E3E15 RS03440
gene id: 1085644:E3E15_RS03440
uniprot id: A0A6M3HT59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1085644:E3E15 RS00860
gene id: 1085644:E3E15_RS00860
uniprot id: A0A6M3HS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1085644:E3E15 RS05355
gene id: 1085644:E3E15_RS05355
uniprot id: A0A6M3HUE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1085644:E3E15 RS06505
gene id: 1085644:E3E15_RS06505
uniprot id: A0A6M3HYF5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1085644:E3E15 RS06905
gene id: 1085644:E3E15_RS06905
uniprot id: A0A6M3HXT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1085644:E3E15 RS07645
gene id: 1085644:E3E15_RS07645
uniprot id: A0A6M3HVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1085644:E3E15 RS03520
gene id: 1085644:E3E15_RS03520
uniprot id: A0A6M3HTW0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1085644:E3E15 RS05860
gene id: 1085644:E3E15_RS05860
uniprot id: A0A6M3HUT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1085644:E3E15 RS04900
gene id: 1085644:E3E15_RS04900
uniprot id: A0A6M3HU24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085644:E3E15 RS03930
gene id: 1085644:E3E15_RS03930
uniprot id: A0A6M3HWB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1085644:E3E15 RS04755
gene id: 1085644:E3E15_RS04755
uniprot id: A0A6M3HU58
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1085644:E3E15 RS03515
gene id: 1085644:E3E15_RS03515
uniprot id: A0A6M3HTI3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1085644:E3E15 RS02310
gene id: 1085644:E3E15_RS02310
uniprot id: A0A6M3HSL4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1085644:E3E15 RS00345
gene id: 1085644:E3E15_RS00345
uniprot id: A0A6M3HVS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1085644:E3E15 RS05085
gene id: 1085644:E3E15_RS05085
uniprot id: A0A6M3HUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1085644:E3E15 RS06015
gene id: 1085644:E3E15_RS06015
uniprot id: A0A6M3HUK3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1085644:E3E15 RS03265
gene id: 1085644:E3E15_RS03265
uniprot id: A0A6M3HVM8
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS07605
gene id: 1085644:E3E15_RS07605
uniprot id: A0A6M3HVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1085644:E3E15 RS06315
gene id: 1085644:E3E15_RS06315
uniprot id: A0A6M3HUQ5
names: Similarity
messages: Belongs to the ParB family.

1085644:E3E15 RS06990
gene id: 1085644:E3E15_RS06990
uniprot id: A0A6M3HV14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1085644:E3E15 RS04780
gene id: 1085644:E3E15_RS04780
uniprot id: A0A6M3HTW3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1085644:E3E15 RS07660
gene id: 1085644:E3E15_RS07660
uniprot id: A0A6M3HVH8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1085644:E3E15 RS00115
gene id: 1085644:E3E15_RS00115
uniprot id: A0A6M3HRK5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1085644:E3E15 RS06190
gene id: 1085644:E3E15_RS06190
uniprot id: A0A6M3HUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1085644:E3E15 RS07045
gene id: 1085644:E3E15_RS07045
uniprot id: A0A6M3HVF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1085644:E3E15 RS06490
gene id: 1085644:E3E15_RS06490
uniprot id: A0A6M3HXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1085644:E3E15 RS01975
gene id: 1085644:E3E15_RS01975
uniprot id: A0A6M3HSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1085644:E3E15 RS04015
gene id: 1085644:E3E15_RS04015
uniprot id: A0A6M3HTN1
names: Similarity
messages: Belongs to the peptidase C59 family.

1085644:E3E15 RS06245
gene id: 1085644:E3E15_RS06245
uniprot id: A0A6M3HUS0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1085644:E3E15 RS00855
gene id: 1085644:E3E15_RS00855
uniprot id: A0A6M3HUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1085644:E3E15 RS03510
gene id: 1085644:E3E15_RS03510
uniprot id: A0A6M3HTF7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1085644:E3E15 RS05960
gene id: 1085644:E3E15_RS05960
uniprot id: A0A6M3HUV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085644:E3E15 RS06930
gene id: 1085644:E3E15_RS06930
uniprot id: A0A6M3HV74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1085644:E3E15 RS01990
gene id: 1085644:E3E15_RS01990
uniprot id: A0A6M3HSV2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1085644:E3E15 RS02395
gene id: 1085644:E3E15_RS02395
uniprot id: A0A6M3HSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1085644:E3E15 RS03125
gene id: 1085644:E3E15_RS03125
uniprot id: A0A6M3HTJ7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1085644:E3E15 RS00070
gene id: 1085644:E3E15_RS00070
uniprot id: A0A6M3HUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1085644:E3E15 RS01350
gene id: 1085644:E3E15_RS01350
uniprot id: A0A6M3HS47
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1085644:E3E15 RS06790
gene id: 1085644:E3E15_RS06790
uniprot id: A0A6M3HV45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1085644:E3E15 RS04695
gene id: 1085644:E3E15_RS04695
uniprot id: A0A6M3HWM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1085644:E3E15 RS00010
gene id: 1085644:E3E15_RS00010
uniprot id: A0A6M3HS17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1085644:E3E15 RS06470
gene id: 1085644:E3E15_RS06470
uniprot id: A0A6M3HV15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1085644:E3E15 RS02600
gene id: 1085644:E3E15_RS02600
uniprot id: A0A6M3HSY5
names: Similarity
messages: Belongs to the HesB/IscA family.

1085644:E3E15 RS04195
gene id: 1085644:E3E15_RS04195
uniprot id: A0A6M3HTM1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1085644:E3E15 RS06510
gene id: 1085644:E3E15_RS06510
uniprot id: A0A6M3HUX8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1085644:E3E15 RS01770
gene id: 1085644:E3E15_RS01770
uniprot id: A0A6M3HSQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1085644:E3E15 RS06995
gene id: 1085644:E3E15_RS06995
uniprot id: A0A6M3HVE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1085644:E3E15 RS07200
gene id: 1085644:E3E15_RS07200
uniprot id: A0A6M3HYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1085644:E3E15 RS03500
gene id: 1085644:E3E15_RS03500
uniprot id: A0A6M3HXV2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1085644:E3E15 RS05095
gene id: 1085644:E3E15_RS05095
uniprot id: A0A6M3HU98
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS03605
gene id: 1085644:E3E15_RS03605
uniprot id: A0A6M3HXX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1085644:E3E15 RS06465
gene id: 1085644:E3E15_RS06465
uniprot id: A0A6M3HZ92
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS06965
gene id: 1085644:E3E15_RS06965
uniprot id: A0A6M3HV83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1085644:E3E15 RS05830
gene id: 1085644:E3E15_RS05830
uniprot id: A0A6M3HXP5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1085644:E3E15 RS03505
gene id: 1085644:E3E15_RS03505
uniprot id: A0A6M3HTR4
names: Similarity
messages: Belongs to the peptidase C59 family.

1085644:E3E15 RS04450
gene id: 1085644:E3E15_RS04450
uniprot id: A0A6M3HU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1085644:E3E15 RS04940
gene id: 1085644:E3E15_RS04940
uniprot id: A0A6M3HYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1085644:E3E15 RS02315
gene id: 1085644:E3E15_RS02315
uniprot id: A0A6M3HSV7
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS05150
gene id: 1085644:E3E15_RS05150
uniprot id: A0A6M3HUA7
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS07040
gene id: 1085644:E3E15_RS07040
uniprot id: A0A6M3HV21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1085644:E3E15 RS07330
gene id: 1085644:E3E15_RS07330
uniprot id: A0A6M3HVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1085644:E3E15 RS04610
gene id: 1085644:E3E15_RS04610
uniprot id: A0A6M3HTX7
names: Similarity
messages: Belongs to the UPF0434 family.

1085644:E3E15 RS03775
gene id: 1085644:E3E15_RS03775
uniprot id: A0A6M3HTC4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1085644:E3E15 RS06915
gene id: 1085644:E3E15_RS06915
uniprot id: A0A6M3HV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1085644:E3E15 RS02450
gene id: 1085644:E3E15_RS02450
uniprot id: A0A6M3HT77
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1085644:E3E15 RS03115
gene id: 1085644:E3E15_RS03115
uniprot id: A0A6M3HT97
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1085644:E3E15 RS03480
gene id: 1085644:E3E15_RS03480
uniprot id: A0A6M3HW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1085644:E3E15 RS06525
gene id: 1085644:E3E15_RS06525
uniprot id: A0A6M3HZA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1085644:E3E15 RS03680
gene id: 1085644:E3E15_RS03680
uniprot id: A0A6M3HTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1085644:E3E15 RS00965
gene id: 1085644:E3E15_RS00965
uniprot id: A0A6M3HUT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1085644:E3E15 RS02035
gene id: 1085644:E3E15_RS02035
uniprot id: A0A6M3HWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS07530
gene id: 1085644:E3E15_RS07530
uniprot id: A0A6M3HVB2
names: Similarity
messages: Belongs to the Skp family.

1085644:E3E15 RS01515
gene id: 1085644:E3E15_RS01515
uniprot id: A0A6M3HSA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1085644:E3E15 RS02715
gene id: 1085644:E3E15_RS02715
uniprot id: A0A6M3HWB9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1085644:E3E15 RS05285
gene id: 1085644:E3E15_RS05285
uniprot id: A0A6M3HU75
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1085644:E3E15 RS02445
gene id: 1085644:E3E15_RS02445
uniprot id: A0A6M3HSZ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS01625
gene id: 1085644:E3E15_RS01625
uniprot id: A0A6M3HSR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085644:E3E15 RS00535
gene id: 1085644:E3E15_RS00535
uniprot id: A0A6M3HUI2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1085644:E3E15 RS04300
gene id: 1085644:E3E15_RS04300
uniprot id: A0A6M3HWG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1085644:E3E15 RS00355
gene id: 1085644:E3E15_RS00355
uniprot id: A0A6M3HRN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1085644:E3E15 RS05560
gene id: 1085644:E3E15_RS05560
uniprot id: A0A6M3HUD0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1085644:E3E15 RS07080
gene id: 1085644:E3E15_RS07080
uniprot id: A0A6M3HV95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1085644:E3E15 RS06955
gene id: 1085644:E3E15_RS06955
uniprot id: A0A6M3HXU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1085644:E3E15 RS01460
gene id: 1085644:E3E15_RS01460
uniprot id: A0A6M3HS97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1085644:E3E15 RS05850
gene id: 1085644:E3E15_RS05850
uniprot id: A0A6M3HUF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1085644:E3E15 RS04690
gene id: 1085644:E3E15_RS04690
uniprot id: A0A6M3HX55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1085644:E3E15 RS03315
gene id: 1085644:E3E15_RS03315
uniprot id: A0A6M3HTS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1085644:E3E15 RS04835
gene id: 1085644:E3E15_RS04835
uniprot id: A0A6M3HU21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1085644:E3E15 RS04850
gene id: 1085644:E3E15_RS04850
uniprot id: A0A6M3HU14
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1085644:E3E15 RS05075
gene id: 1085644:E3E15_RS05075
uniprot id: A0A6M3HYK5
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS00900
gene id: 1085644:E3E15_RS00900
uniprot id: A0A6M3HV90
names: Similarity
messages: Belongs to the BolA/IbaG family.

1085644:E3E15 RS01465
gene id: 1085644:E3E15_RS01465
uniprot id: A0A6M3HSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1085644:E3E15 RS05460
gene id: 1085644:E3E15_RS05460
uniprot id: A0A6M3HUV1
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1085644:E3E15 RS01015
gene id: 1085644:E3E15_RS01015
uniprot id: A0A6M3HVA4
names: Similarity
messages: Belongs to the ArsC family.

1085644:E3E15 RS06610
gene id: 1085644:E3E15_RS06610
uniprot id: A0A6M3HV94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1085644:E3E15 RS01450
gene id: 1085644:E3E15_RS01450
uniprot id: A0A6M3HSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1085644:E3E15 RS00005
gene id: 1085644:E3E15_RS00005
uniprot id: A0A6M3HRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1085644:E3E15 RS05130
gene id: 1085644:E3E15_RS05130
uniprot id: A0A6M3HU56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1085644:E3E15 RS03455
gene id: 1085644:E3E15_RS03455
uniprot id: A0A6M3HTQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1085644:E3E15 RS07005
gene id: 1085644:E3E15_RS07005
uniprot id: A0A6M3HXV6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1085644:E3E15 RS05855
gene id: 1085644:E3E15_RS05855
uniprot id: A0A6M3HYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1085644:E3E15 RS01775
gene id: 1085644:E3E15_RS01775
uniprot id: A0A6M3HSF7
names: Subcellular Location Annotation
messages: Cytoplasm

1085644:E3E15 RS05820
gene id: 1085644:E3E15_RS05820
uniprot id: A0A6M3HUK1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1085644:E3E15 RS04110
gene id: 1085644:E3E15_RS04110
uniprot id: A0A6M3HY47
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1085644:E3E15 RS03960
gene id: 1085644:E3E15_RS03960
uniprot id: A0A6M3HTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1085644:E3E15 RS06910
gene id: 1085644:E3E15_RS06910
uniprot id: A0A6M3HUX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1085644:E3E15 RS06500
gene id: 1085644:E3E15_RS06500
uniprot id: A0A6M3HUQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1085644:E3E15 RS06495
gene id: 1085644:E3E15_RS06495
uniprot id: A0A6M3HXL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1085644:E3E15 RS01875
gene id: 1085644:E3E15_RS01875
uniprot id: A0A6M3HST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1085644:E3E15 RS06745
gene id: 1085644:E3E15_RS06745
uniprot id: A0A6M3HUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS01980
gene id: 1085644:E3E15_RS01980
uniprot id: A0A6M3HSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1085644:E3E15 RS01135
gene id: 1085644:E3E15_RS01135
uniprot id: A0A6M3HSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1085644:E3E15 RS00805
gene id: 1085644:E3E15_RS00805
uniprot id: A0A6M3HUP1
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS06580
gene id: 1085644:E3E15_RS06580
uniprot id: A0A6M3HUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1085644:E3E15 RS00505
gene id: 1085644:E3E15_RS00505
uniprot id: A0A6M3HVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1085644:E3E15 RS07060
gene id: 1085644:E3E15_RS07060
uniprot id: A0A6M3HUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1085644:E3E15 RS03725
gene id: 1085644:E3E15_RS03725
uniprot id: A0A6M3HXZ3
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS00720
gene id: 1085644:E3E15_RS00720
uniprot id: A0A6M3HW17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1085644:E3E15 RS02655
gene id: 1085644:E3E15_RS02655
uniprot id: A0A6M3HT32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1085644:E3E15 RS06615
gene id: 1085644:E3E15_RS06615
uniprot id: A0A6M3HY18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085644:E3E15 RS04295
gene id: 1085644:E3E15_RS04295
uniprot id: A0A6M3HWZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1085644:E3E15 RS07675
gene id: 1085644:E3E15_RS07675
uniprot id: A0A6M3HVS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1085644:E3E15 RS03820
gene id: 1085644:E3E15_RS03820
uniprot id: A0A6M3HTG4
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS02295
gene id: 1085644:E3E15_RS02295
uniprot id: A0A6M3HW13
names: Subcellular Location Annotation
messages: Membrane

1085644:E3E15 RS05455
gene id: 1085644:E3E15_RS05455
uniprot id: A0A6M3HUF7
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1085644:E3E15 RS06970
gene id: 1085644:E3E15_RS06970
uniprot id: A0A6M3HV48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1085644:E3E15 RS00690
gene id: 1085644:E3E15_RS00690
uniprot id: A0A6M3HSB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1085644:E3E15 RS07690
gene id: 1085644:E3E15_RS07690
uniprot id: A0A6M3HVF0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1085644:E3E15 RS06750
gene id: 1085644:E3E15_RS06750
uniprot id: A0A6M3HZG1
names: Similarity
messages: Belongs to the FBPase class 2 family.

1085644:E3E15 RS00705
gene id: 1085644:E3E15_RS00705
uniprot id: A0A6M3HS40
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1085644:E3E15 RS02930
gene id: 1085644:E3E15_RS02930
uniprot id: A0A6M3HWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1085644:E3E15 RS02500
gene id: 1085644:E3E15_RS02500
uniprot id: A0A6M3HSV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1085644:E3E15 RS03600
gene id: 1085644:E3E15_RS03600
uniprot id: A0A6M3HTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1085644:E3E15 RS03110
gene id: 1085644:E3E15_RS03110
uniprot id: A0A6M3HT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane