1085623:GNIT RS04430
gene id: 1085623:GNIT_RS04430
uniprot id: G4QFX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1085623:GNIT RS10660
gene id: 1085623:GNIT_RS10660
uniprot id: G4QKN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS16880
gene id: 1085623:GNIT_RS16880
uniprot id: G4QNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS11510
gene id: 1085623:GNIT_RS11510
uniprot id: G4QHX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1085623:GNIT RS08905
gene id: 1085623:GNIT_RS08905
uniprot id: G4QHJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1085623:GNIT RS06655
gene id: 1085623:GNIT_RS06655
uniprot id: G4QL48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS14855
gene id: 1085623:GNIT_RS14855
uniprot id: G4QIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1085623:GNIT RS08385
gene id: 1085623:GNIT_RS08385
uniprot id: G4QGS9
names: Similarity
messages: Belongs to the WrbA family.

1085623:GNIT RS12775
gene id: 1085623:GNIT_RS12775
uniprot id: G4QMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1085623:GNIT RS02005
gene id: 1085623:GNIT_RS02005
uniprot id: G4QJH3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS03590
gene id: 1085623:GNIT_RS03590
uniprot id: G4QJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1085623:GNIT RS07520
gene id: 1085623:GNIT_RS07520
uniprot id: G4QH68
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1085623:GNIT RS10320
gene id: 1085623:GNIT_RS10320
uniprot id: G4QHP3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1085623:GNIT RS01250
gene id: 1085623:GNIT_RS01250
uniprot id: G4QF73
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1085623:GNIT RS12760
gene id: 1085623:GNIT_RS12760
uniprot id: G4QMD0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS07705
gene id: 1085623:GNIT_RS07705
uniprot id: G4QHA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS16930
gene id: 1085623:GNIT_RS16930
uniprot id: G4QNW2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1085623:GNIT RS05165
gene id: 1085623:GNIT_RS05165
uniprot id: G4QG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1085623:GNIT RS01305
gene id: 1085623:GNIT_RS01305
uniprot id: G4QF84
names: Similarity
messages: Belongs to the GST superfamily.

1085623:GNIT RS08170
gene id: 1085623:GNIT_RS08170
uniprot id: G4QLG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1085623:GNIT RS10690
gene id: 1085623:GNIT_RS10690
uniprot id: G4QKP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1085623:GNIT RS09635
gene id: 1085623:GNIT_RS09635
uniprot id: G4QLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS16475
gene id: 1085623:GNIT_RS16475
uniprot id: G4QNL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1085623:GNIT RS03450
gene id: 1085623:GNIT_RS03450
uniprot id: G4QFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1085623:GNIT RS00060
gene id: 1085623:GNIT_RS00060
uniprot id: G4QEE5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1085623:GNIT RS09565
gene id: 1085623:GNIT_RS09565
uniprot id: G4QLL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS15120
gene id: 1085623:GNIT_RS15120
uniprot id: G4QE09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS07030
gene id: 1085623:GNIT_RS07030
uniprot id: G4QEQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1085623:GNIT RS04175
gene id: 1085623:GNIT_RS04175
uniprot id: G4QJX3
names: Similarity
messages: Belongs to the glutamate synthase family.

1085623:GNIT RS07995
gene id: 1085623:GNIT_RS07995
uniprot id: G4QLD2
names: Similarity
messages: Belongs to the SufE family.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1085623:GNIT RS09315
gene id: 1085623:GNIT_RS09315
uniprot id: G4QKK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS01260
gene id: 1085623:GNIT_RS01260
uniprot id: G4QF75
names: Similarity
messages: Belongs to the MoaD family.

1085623:GNIT RS04300
gene id: 1085623:GNIT_RS04300
uniprot id: G4QFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1085623:GNIT RS05770
gene id: 1085623:GNIT_RS05770
uniprot id: G4QKE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1085623:GNIT RS05810
gene id: 1085623:GNIT_RS05810
uniprot id: G4QKW1
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS00300
gene id: 1085623:GNIT_RS00300
uniprot id: G4QEV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS07185
gene id: 1085623:GNIT_RS07185
uniprot id: G4QGJ1
names: Similarity
messages: Belongs to the peptidase S9C family.

1085623:GNIT RS05275
gene id: 1085623:GNIT_RS05275
uniprot id: G4QG75
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1085623:GNIT RS14075
gene id: 1085623:GNIT_RS14075
uniprot id: G4QMY0
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS16655
gene id: 1085623:GNIT_RS16655
uniprot id: G4QNQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS11800
gene id: 1085623:GNIT_RS11800
uniprot id: G4QM06
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1085623:GNIT RS03670
gene id: 1085623:GNIT_RS03670
uniprot id: G4QJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1085623:GNIT RS09280
gene id: 1085623:GNIT_RS09280
uniprot id: G4QKJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1085623:GNIT RS07770
gene id: 1085623:GNIT_RS07770
uniprot id: G4QHC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1085623:GNIT RS15990
gene id: 1085623:GNIT_RS15990
uniprot id: G4QN50
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS11650
gene id: 1085623:GNIT_RS11650
uniprot id: G4QI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1085623:GNIT RS12580
gene id: 1085623:GNIT_RS12580
uniprot id: G4QM93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1085623:GNIT RS11575
gene id: 1085623:GNIT_RS11575
uniprot id: G4QHZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1085623:GNIT RS16330
gene id: 1085623:GNIT_RS16330
uniprot id: G4QNC2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1085623:GNIT RS06410
gene id: 1085623:GNIT_RS06410
uniprot id: G4QGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS04535
gene id: 1085623:GNIT_RS04535
uniprot id: G4QG03
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1085623:GNIT RS14440
gene id: 1085623:GNIT_RS14440
uniprot id: G4QDW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1085623:GNIT RS08490
gene id: 1085623:GNIT_RS08490
uniprot id: G4QGV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1085623:GNIT RS15745
gene id: 1085623:GNIT_RS15745
uniprot id: G4QMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1085623:GNIT RS14220
gene id: 1085623:GNIT_RS14220
uniprot id: G4QDR6
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS04825
gene id: 1085623:GNIT_RS04825
uniprot id: G4QK31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS08225
gene id: 1085623:GNIT_RS08225
uniprot id: G4QLH6
names: Similarity
messages: Belongs to the fabD family.

1085623:GNIT RS03365
gene id: 1085623:GNIT_RS03365
uniprot id: G4QFR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1085623:GNIT RS14745
gene id: 1085623:GNIT_RS14745
uniprot id: G4QIP8
names: Similarity
messages: Belongs to the GSP E family.

1085623:GNIT RS05455
gene id: 1085623:GNIT_RS05455
uniprot id: G4QK74
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1085623:GNIT RS14735
gene id: 1085623:GNIT_RS14735
uniprot id: G4QIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS14200
gene id: 1085623:GNIT_RS14200
uniprot id: G4QDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1085623:GNIT RS12725
gene id: 1085623:GNIT_RS12725
uniprot id: G4QMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS03640
gene id: 1085623:GNIT_RS03640
uniprot id: G4QJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1085623:GNIT RS14465
gene id: 1085623:GNIT_RS14465
uniprot id: G4QDW5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1085623:GNIT RS11640
gene id: 1085623:GNIT_RS11640
uniprot id: G4QI09
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1085623:GNIT RS15520
gene id: 1085623:GNIT_RS15520
uniprot id: G4QE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1085623:GNIT RS11455
gene id: 1085623:GNIT_RS11455
uniprot id: G4QHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1085623:GNIT RS05145
gene id: 1085623:GNIT_RS05145
uniprot id: G4QG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1085623:GNIT RS00680
gene id: 1085623:GNIT_RS00680
uniprot id: G4QIV7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1085623:GNIT RS00580
gene id: 1085623:GNIT_RS00580
uniprot id: G4QIT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS08075
gene id: 1085623:GNIT_RS08075
uniprot id: G4QLE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS11400
gene id: 1085623:GNIT_RS11400
uniprot id: G4QHV6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1085623:GNIT RS00245
gene id: 1085623:GNIT_RS00245
uniprot id: G4QEU4
names: Similarity
messages: Belongs to the UPF0758 family.

1085623:GNIT RS11235
gene id: 1085623:GNIT_RS11235
uniprot id: G4QLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1085623:GNIT RS06485
gene id: 1085623:GNIT_RS06485
uniprot id: G4QGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS13565
gene id: 1085623:GNIT_RS13565
uniprot id: G4QMJ9
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS08720
gene id: 1085623:GNIT_RS08720
uniprot id: G4QHF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1085623:GNIT RS04275
gene id: 1085623:GNIT_RS04275
uniprot id: G4QFU5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1085623:GNIT RS03075
gene id: 1085623:GNIT_RS03075
uniprot id: G4QEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1085623:GNIT RS13445
gene id: 1085623:GNIT_RS13445
uniprot id: G4QMH2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS03205
gene id: 1085623:GNIT_RS03205
uniprot id: G4QFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1085623:GNIT RS08435
gene id: 1085623:GNIT_RS08435
uniprot id: G4QGU0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1085623:GNIT RS02120
gene id: 1085623:GNIT_RS02120
uniprot id: G4QFH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1085623:GNIT RS11135
gene id: 1085623:GNIT_RS11135
uniprot id: G4QLU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1085623:GNIT RS16960
gene id: 1085623:GNIT_RS16960
uniprot id: G4QNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS13845
gene id: 1085623:GNIT_RS13845
uniprot id: G4QMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1085623:GNIT RS07035
gene id: 1085623:GNIT_RS07035
uniprot id: G4QER0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13410
gene id: 1085623:GNIT_RS13410
uniprot id: G4QMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1085623:GNIT RS14055
gene id: 1085623:GNIT_RS14055
uniprot id: G4QMX5
names: Similarity
messages: Belongs to the peptidase M16 family.

1085623:GNIT RS08025
gene id: 1085623:GNIT_RS08025
uniprot id: G4QLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS11315
gene id: 1085623:GNIT_RS11315
uniprot id: G4QLY2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1085623:GNIT RS15550
gene id: 1085623:GNIT_RS15550
uniprot id: G4QE98
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS11045
gene id: 1085623:GNIT_RS11045
uniprot id: G4QLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS06520
gene id: 1085623:GNIT_RS06520
uniprot id: G4QGH1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1085623:GNIT RS04995
gene id: 1085623:GNIT_RS04995
uniprot id: G4QK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1085623:GNIT RS10460
gene id: 1085623:GNIT_RS10460
uniprot id: G4QHS1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1085623:GNIT RS12170
gene id: 1085623:GNIT_RS12170
uniprot id: G4QI44
names: Similarity
messages: Belongs to the asparagine synthetase family.

1085623:GNIT RS13055
gene id: 1085623:GNIT_RS13055
uniprot id: G4QID0
names: Similarity
messages: Belongs to the YggT family.

1085623:GNIT RS16230
gene id: 1085623:GNIT_RS16230
uniprot id: G4QNA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1085623:GNIT RS08940
gene id: 1085623:GNIT_RS08940
uniprot id: G4QHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1085623:GNIT RS07155
gene id: 1085623:GNIT_RS07155
uniprot id: G4QGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1085623:GNIT RS11160
gene id: 1085623:GNIT_RS11160
uniprot id: G4QLV0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1085623:GNIT RS13545
gene id: 1085623:GNIT_RS13545
uniprot id: G4QMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1085623:GNIT RS12960
gene id: 1085623:GNIT_RS12960
uniprot id: G4QMQ4
names: Similarity
messages: Belongs to the GppA/Ppx family.

1085623:GNIT RS11660
gene id: 1085623:GNIT_RS11660
uniprot id: G4QI13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1085623:GNIT RS12985
gene id: 1085623:GNIT_RS12985
uniprot id: G4QIB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1085623:GNIT RS05825
gene id: 1085623:GNIT_RS05825
uniprot id: G4QKW4
names: Similarity
messages: Belongs to the SUI1 family.

1085623:GNIT RS09460
gene id: 1085623:GNIT_RS09460
uniprot id: G4QLJ1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1085623:GNIT RS10815
gene id: 1085623:GNIT_RS10815
uniprot id: G4QKR8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1085623:GNIT RS05160
gene id: 1085623:GNIT_RS05160
uniprot id: G4QG51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS14905
gene id: 1085623:GNIT_RS14905
uniprot id: G4QJ94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS09640
gene id: 1085623:GNIT_RS09640
uniprot id: G4QLM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1085623:GNIT RS08280
gene id: 1085623:GNIT_RS08280
uniprot id: G4QGQ9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1085623:GNIT RS15310
gene id: 1085623:GNIT_RS15310
uniprot id: G4QE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS07875
gene id: 1085623:GNIT_RS07875
uniprot id: G4QHE3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1085623:GNIT RS14110
gene id: 1085623:GNIT_RS14110
uniprot id: G4QMY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1085623:GNIT RS07670
gene id: 1085623:GNIT_RS07670
uniprot id: G4QHA0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1085623:GNIT RS14815
gene id: 1085623:GNIT_RS14815
uniprot id: G4QIR4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1085623:GNIT RS04805
gene id: 1085623:GNIT_RS04805
uniprot id: G4QK27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1085623:GNIT RS10285
gene id: 1085623:GNIT_RS10285
uniprot id: G4QHN6
names: Similarity
messages: Belongs to the PhoH family.

1085623:GNIT RS09650
gene id: 1085623:GNIT_RS09650
uniprot id: G4QLN1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1085623:GNIT RS07675
gene id: 1085623:GNIT_RS07675
uniprot id: G4QHA1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1085623:GNIT RS11500
gene id: 1085623:GNIT_RS11500
uniprot id: G4QHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1085623:GNIT RS11075
gene id: 1085623:GNIT_RS11075
uniprot id: G4QLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1085623:GNIT RS10665
gene id: 1085623:GNIT_RS10665
uniprot id: G4QKP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1085623:GNIT RS04815
gene id: 1085623:GNIT_RS04815
uniprot id: G4QK29
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1085623:GNIT RS05630
gene id: 1085623:GNIT_RS05630
uniprot id: G4QKB3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS16835
gene id: 1085623:GNIT_RS16835
uniprot id: G4QNU1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS07820
gene id: 1085623:GNIT_RS07820
uniprot id: G4QHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1085623:GNIT RS11030
gene id: 1085623:GNIT_RS11030
uniprot id: G4QLS6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1085623:GNIT RS01170
gene id: 1085623:GNIT_RS01170
uniprot id: G4QF55
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1085623:GNIT RS08975
gene id: 1085623:GNIT_RS08975
uniprot id: G4QHL0
names: Similarity
messages: Belongs to the peptidase M1 family.

1085623:GNIT RS09035
gene id: 1085623:GNIT_RS09035
uniprot id: G4QHM2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1085623:GNIT RS09845
gene id: 1085623:GNIT_RS09845
uniprot id: G4QGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1085623:GNIT RS15185
gene id: 1085623:GNIT_RS15185
uniprot id: G4QE21
names: Similarity
messages: Belongs to the intimin/invasin family.

1085623:GNIT RS01765
gene id: 1085623:GNIT_RS01765
uniprot id: G4QJB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1085623:GNIT RS09235
gene id: 1085623:GNIT_RS09235
uniprot id: G4QKI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS15500
gene id: 1085623:GNIT_RS15500
uniprot id: G4QE87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1085623:GNIT RS07135
gene id: 1085623:GNIT_RS07135
uniprot id: G4QGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1085623:GNIT RS07885
gene id: 1085623:GNIT_RS07885
uniprot id: G4QLA9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1085623:GNIT RS17485
gene id: 1085623:GNIT_RS17485
uniprot id: G4QNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1085623:GNIT RS17495
gene id: 1085623:GNIT_RS17495
uniprot id: G4QNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1085623:GNIT RS11805
gene id: 1085623:GNIT_RS11805
uniprot id: G4QM07
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1085623:GNIT RS15615
gene id: 1085623:GNIT_RS15615
uniprot id: G4QEB2
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13225
gene id: 1085623:GNIT_RS13225
uniprot id: G4QIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1085623:GNIT RS01210
gene id: 1085623:GNIT_RS01210
uniprot id: G4QF63
names: Similarity
messages: Belongs to the FeoA family.

1085623:GNIT RS01980
gene id: 1085623:GNIT_RS01980
uniprot id: G4QJG7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1085623:GNIT RS12700
gene id: 1085623:GNIT_RS12700
uniprot id: G4QMB8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1085623:GNIT RS14425
gene id: 1085623:GNIT_RS14425
uniprot id: G4QDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1085623:GNIT RS08870
gene id: 1085623:GNIT_RS08870
uniprot id: G4QHI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1085623:GNIT RS00585
gene id: 1085623:GNIT_RS00585
uniprot id: G4QIT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS05310
gene id: 1085623:GNIT_RS05310
uniprot id: G4QG82
names: Similarity
messages: Belongs to the CFA/CMAS family.

1085623:GNIT RS08410
gene id: 1085623:GNIT_RS08410
uniprot id: G4QGT4
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS17725
gene id: 1085623:GNIT_RS17725
uniprot id: G4QI46
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1085623:GNIT RS04185
gene id: 1085623:GNIT_RS04185
uniprot id: G4QJX6
names: Similarity
messages: Belongs to the IMPACT family.

1085623:GNIT RS05835
gene id: 1085623:GNIT_RS05835
uniprot id: G4QKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1085623:GNIT RS05760
gene id: 1085623:GNIT_RS05760
uniprot id: G4QKE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1085623:GNIT RS07505
gene id: 1085623:GNIT_RS07505
uniprot id: G4QH65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1085623:GNIT RS04440
gene id: 1085623:GNIT_RS04440
uniprot id: G4QFY1
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

1085623:GNIT RS03370
gene id: 1085623:GNIT_RS03370
uniprot id: G4QFR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS03435
gene id: 1085623:GNIT_RS03435
uniprot id: G4QFS7
names: Similarity
messages: Belongs to the RecJ family.

1085623:GNIT RS04910
gene id: 1085623:GNIT_RS04910
uniprot id: G4QK49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1085623:GNIT RS00635
gene id: 1085623:GNIT_RS00635
uniprot id: G4QIU8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS02685
gene id: 1085623:GNIT_RS02685
uniprot id: G4QJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS04305
gene id: 1085623:GNIT_RS04305
uniprot id: G4QFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1085623:GNIT RS00410
gene id: 1085623:GNIT_RS00410
uniprot id: G4QEX8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1085623:GNIT RS12695
gene id: 1085623:GNIT_RS12695
uniprot id: G4QMB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1085623:GNIT RS02835
gene id: 1085623:GNIT_RS02835
uniprot id: G4QEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1085623:GNIT RS14455
gene id: 1085623:GNIT_RS14455
uniprot id: G4QDW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1085623:GNIT RS16075
gene id: 1085623:GNIT_RS16075
uniprot id: G4QN69
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1085623:GNIT RS08605
gene id: 1085623:GNIT_RS08605
uniprot id: G4QGX3
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

1085623:GNIT RS10940
gene id: 1085623:GNIT_RS10940
uniprot id: G4QKU4
names: Subcellular Location Annotation
messages: nucleolus

1085623:GNIT RS11655
gene id: 1085623:GNIT_RS11655
uniprot id: G4QI12
names: Similarity
messages: Belongs to the skp family.

1085623:GNIT RS05435
gene id: 1085623:GNIT_RS05435
uniprot id: G4QK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1085623:GNIT RS04940
gene id: 1085623:GNIT_RS04940
uniprot id: G4QK56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS15910
gene id: 1085623:GNIT_RS15910
uniprot id: G4QN34
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1085623:GNIT RS01130
gene id: 1085623:GNIT_RS01130
uniprot id: G4QF47
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1085623:GNIT RS13865
gene id: 1085623:GNIT_RS13865
uniprot id: G4QMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1085623:GNIT RS03665
gene id: 1085623:GNIT_RS03665
uniprot id: G4QJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1085623:GNIT RS13660
gene id: 1085623:GNIT_RS13660
uniprot id: G4QMM0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1085623:GNIT RS16120
gene id: 1085623:GNIT_RS16120
uniprot id: G4QN79
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS14065
gene id: 1085623:GNIT_RS14065
uniprot id: G4QMX7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1085623:GNIT RS16860
gene id: 1085623:GNIT_RS16860
uniprot id: G4QNU7
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS11295
gene id: 1085623:GNIT_RS11295
uniprot id: G4QLX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1085623:GNIT RS03635
gene id: 1085623:GNIT_RS03635
uniprot id: G4QJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1085623:GNIT RS02910
gene id: 1085623:GNIT_RS02910
uniprot id: G4QEK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1085623:GNIT RS16925
gene id: 1085623:GNIT_RS16925
uniprot id: G4QNW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS10105
gene id: 1085623:GNIT_RS10105
uniprot id: G4QH42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1085623:GNIT RS03115
gene id: 1085623:GNIT_RS03115
uniprot id: G4QFL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1085623:GNIT RS09605
gene id: 1085623:GNIT_RS09605
uniprot id: G4QLM1
names: Similarity
messages: Belongs to the NodU/CmcH family.

1085623:GNIT RS09910
gene id: 1085623:GNIT_RS09910
uniprot id: G4QH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1085623:GNIT RS12655
gene id: 1085623:GNIT_RS12655
uniprot id: G4QMA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1085623:GNIT RS03845
gene id: 1085623:GNIT_RS03845
uniprot id: G4QJ85
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09105
gene id: 1085623:GNIT_RS09105
uniprot id: G4QKF6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1085623:GNIT RS12045
gene id: 1085623:GNIT_RS12045
uniprot id: G4QM56
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1085623:GNIT RS06975
gene id: 1085623:GNIT_RS06975
uniprot id: G4QEP8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1085623:GNIT RS08175
gene id: 1085623:GNIT_RS08175
uniprot id: G4QLG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1085623:GNIT RS11620
gene id: 1085623:GNIT_RS11620
uniprot id: G4QI05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1085623:GNIT RS01340
gene id: 1085623:GNIT_RS01340
uniprot id: G4QF91
names: Similarity
messages: Belongs to the FPG family.

1085623:GNIT RS09880
gene id: 1085623:GNIT_RS09880
uniprot id: G4QGZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1085623:GNIT RS09925
gene id: 1085623:GNIT_RS09925
uniprot id: G4QH05
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1085623:GNIT RS05780
gene id: 1085623:GNIT_RS05780
uniprot id: G4QKV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1085623:GNIT RS10935
gene id: 1085623:GNIT_RS10935
uniprot id: G4QKU3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1085623:GNIT RS13895
gene id: 1085623:GNIT_RS13895
uniprot id: G4QMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS12500
gene id: 1085623:GNIT_RS12500
uniprot id: G4QIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS14010
gene id: 1085623:GNIT_RS14010
uniprot id: G4QMW6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS09525
gene id: 1085623:GNIT_RS09525
uniprot id: G4QLK4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1085623:GNIT RS01600
gene id: 1085623:GNIT_RS01600
uniprot id: G4QFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1085623:GNIT RS03345
gene id: 1085623:GNIT_RS03345
uniprot id: G4QFQ8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1085623:GNIT RS10430
gene id: 1085623:GNIT_RS10430
uniprot id: G4QHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS05555
gene id: 1085623:GNIT_RS05555
uniprot id: G4QK95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1085623:GNIT RS02380
gene id: 1085623:GNIT_RS02380
uniprot id: G4QJJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1085623:GNIT RS01315
gene id: 1085623:GNIT_RS01315
uniprot id: G4QF86
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1085623:GNIT RS08530
gene id: 1085623:GNIT_RS08530
uniprot id: G4QGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1085623:GNIT RS04680
gene id: 1085623:GNIT_RS04680
uniprot id: G4QK00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1085623:GNIT RS17505
gene id: 1085623:GNIT_RS17505
uniprot id: G4QNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1085623:GNIT RS14060
gene id: 1085623:GNIT_RS14060
uniprot id: G4QMX6
names: Similarity
messages: Belongs to the peptidase M16 family.

1085623:GNIT RS08445
gene id: 1085623:GNIT_RS08445
uniprot id: G4QGU2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1085623:GNIT RS03490
gene id: 1085623:GNIT_RS03490
uniprot id: G4QFT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1085623:GNIT RS02670
gene id: 1085623:GNIT_RS02670
uniprot id: G4QJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1085623:GNIT RS09145
gene id: 1085623:GNIT_RS09145
uniprot id: G4QKG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS17075
gene id: 1085623:GNIT_RS17075
uniprot id: G4QNZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1085623:GNIT RS00255
gene id: 1085623:GNIT_RS00255
uniprot id: G4QEU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1085623:GNIT RS14395
gene id: 1085623:GNIT_RS14395
uniprot id: G4QDV2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1085623:GNIT RS12475
gene id: 1085623:GNIT_RS12475
uniprot id: G4QIA9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

1085623:GNIT RS09760
gene id: 1085623:GNIT_RS09760
uniprot id: G4QLQ4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1085623:GNIT RS06795
gene id: 1085623:GNIT_RS06795
uniprot id: G4QL79
names: Similarity
messages: Belongs to the YciI family.

1085623:GNIT RS16375
gene id: 1085623:GNIT_RS16375
uniprot id: G4QND4
names: Similarity
messages: Belongs to the GARS family.

1085623:GNIT RS06860
gene id: 1085623:GNIT_RS06860
uniprot id: G4QL92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1085623:GNIT RS04705
gene id: 1085623:GNIT_RS04705
uniprot id: G4QK06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS10045
gene id: 1085623:GNIT_RS10045
uniprot id: G4QH29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1085623:GNIT RS12855
gene id: 1085623:GNIT_RS12855
uniprot id: G4QME9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1085623:GNIT RS09330
gene id: 1085623:GNIT_RS09330
uniprot id: G4QKK5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1085623:GNIT RS01445
gene id: 1085623:GNIT_RS01445
uniprot id: G4QFB3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS05640
gene id: 1085623:GNIT_RS05640
uniprot id: G4QKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1085623:GNIT RS10410
gene id: 1085623:GNIT_RS10410
uniprot id: G4QHR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13005
gene id: 1085623:GNIT_RS13005
uniprot id: G4QIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1085623:GNIT RS15055
gene id: 1085623:GNIT_RS15055
uniprot id: G4QDZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1085623:GNIT RS05445
gene id: 1085623:GNIT_RS05445
uniprot id: G4QK72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1085623:GNIT RS05750
gene id: 1085623:GNIT_RS05750
uniprot id: G4QKE0
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS01325
gene id: 1085623:GNIT_RS01325
uniprot id: G4QF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1085623:GNIT RS05010
gene id: 1085623:GNIT_RS05010
uniprot id: G4QK65
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1085623:GNIT RS03260
gene id: 1085623:GNIT_RS03260
uniprot id: G4QFP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS06450
gene id: 1085623:GNIT_RS06450
uniprot id: G4QGF7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1085623:GNIT RS08710
gene id: 1085623:GNIT_RS08710
uniprot id: G4QHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1085623:GNIT RS00540
gene id: 1085623:GNIT_RS00540
uniprot id: G4QIS8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1085623:GNIT RS06430
gene id: 1085623:GNIT_RS06430
uniprot id: G4QGF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13600
gene id: 1085623:GNIT_RS13600
uniprot id: G4QMK7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1085623:GNIT RS10345
gene id: 1085623:GNIT_RS10345
uniprot id: G4QHP8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1085623:GNIT RS17540
gene id: 1085623:GNIT_RS17540
uniprot id: G4QNJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1085623:GNIT RS13405
gene id: 1085623:GNIT_RS13405
uniprot id: G4QMG4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1085623:GNIT RS05450
gene id: 1085623:GNIT_RS05450
uniprot id: G4QK73
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS01895
gene id: 1085623:GNIT_RS01895
uniprot id: G4QJE8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1085623:GNIT RS02155
gene id: 1085623:GNIT_RS02155
uniprot id: G4QFI4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1085623:GNIT RS01835
gene id: 1085623:GNIT_RS01835
uniprot id: G4QJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1085623:GNIT RS08240
gene id: 1085623:GNIT_RS08240
uniprot id: G4QLH9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1085623:GNIT RS01040
gene id: 1085623:GNIT_RS01040
uniprot id: G4QF29
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1085623:GNIT RS02335
gene id: 1085623:GNIT_RS02335
uniprot id: G4QJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1085623:GNIT RS14970
gene id: 1085623:GNIT_RS14970
uniprot id: G4QDX7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1085623:GNIT RS10300
gene id: 1085623:GNIT_RS10300
uniprot id: G4QHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS01485
gene id: 1085623:GNIT_RS01485
uniprot id: G4QFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1085623:GNIT RS10550
gene id: 1085623:GNIT_RS10550
uniprot id: G4QHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1085623:GNIT RS05050
gene id: 1085623:GNIT_RS05050
uniprot id: G4QG29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1085623:GNIT RS04030
gene id: 1085623:GNIT_RS04030
uniprot id: G4QJU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1085623:GNIT RS09815
gene id: 1085623:GNIT_RS09815
uniprot id: G4QLR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1085623:GNIT RS14660
gene id: 1085623:GNIT_RS14660
uniprot id: G4QIN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1085623:GNIT RS06535
gene id: 1085623:GNIT_RS06535
uniprot id: G4QGH4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1085623:GNIT RS09160
gene id: 1085623:GNIT_RS09160
uniprot id: G4QKG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS09655
gene id: 1085623:GNIT_RS09655
uniprot id: G4QLN2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1085623:GNIT RS05505
gene id: 1085623:GNIT_RS05505
uniprot id: G4QK84
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS05865
gene id: 1085623:GNIT_RS05865
uniprot id: G4QKX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1085623:GNIT RS11205
gene id: 1085623:GNIT_RS11205
uniprot id: G4QLV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1085623:GNIT RS08980
gene id: 1085623:GNIT_RS08980
uniprot id: G4QHL1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS01515
gene id: 1085623:GNIT_RS01515
uniprot id: G4QFD0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS14480
gene id: 1085623:GNIT_RS14480
uniprot id: G4QDW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS01905
gene id: 1085623:GNIT_RS01905
uniprot id: G4QJF0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

1085623:GNIT RS14520
gene id: 1085623:GNIT_RS14520
uniprot id: G4QIK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS08790
gene id: 1085623:GNIT_RS08790
uniprot id: G4QHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1085623:GNIT RS10015
gene id: 1085623:GNIT_RS10015
uniprot id: G4QH23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1085623:GNIT RS10495
gene id: 1085623:GNIT_RS10495
uniprot id: G4QHT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1085623:GNIT RS08200
gene id: 1085623:GNIT_RS08200
uniprot id: G4QLH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1085623:GNIT RS06865
gene id: 1085623:GNIT_RS06865
uniprot id: G4QL93
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1085623:GNIT RS11115
gene id: 1085623:GNIT_RS11115
uniprot id: G4QLU0
names: Similarity
messages: Belongs to the peptidase M13 family.

1085623:GNIT RS01655
gene id: 1085623:GNIT_RS01655
uniprot id: G4QFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1085623:GNIT RS02095
gene id: 1085623:GNIT_RS02095
uniprot id: G4QFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1085623:GNIT RS10435
gene id: 1085623:GNIT_RS10435
uniprot id: G4QHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS03965
gene id: 1085623:GNIT_RS03965
uniprot id: G4QJT1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1085623:GNIT RS16710
gene id: 1085623:GNIT_RS16710
uniprot id: G4QNR3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1085623:GNIT RS14460
gene id: 1085623:GNIT_RS14460
uniprot id: G4QDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1085623:GNIT RS08495
gene id: 1085623:GNIT_RS08495
uniprot id: G4QGV3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1085623:GNIT RS11435
gene id: 1085623:GNIT_RS11435
uniprot id: G4QHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1085623:GNIT RS02465
gene id: 1085623:GNIT_RS02465
uniprot id: G4QJL4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1085623:GNIT RS06790
gene id: 1085623:GNIT_RS06790
uniprot id: G4QL78
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1085623:GNIT RS13835
gene id: 1085623:GNIT_RS13835
uniprot id: G4QMS6
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1085623:GNIT RS08745
gene id: 1085623:GNIT_RS08745
uniprot id: G4QHG0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1085623:GNIT RS15385
gene id: 1085623:GNIT_RS15385
uniprot id: G4QE64
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1085623:GNIT RS06895
gene id: 1085623:GNIT_RS06895
uniprot id: G4QLA1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS17155
gene id: 1085623:GNIT_RS17155
uniprot id: G4QP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085623:GNIT RS13920
gene id: 1085623:GNIT_RS13920
uniprot id: G4QMU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1085623:GNIT RS04190
gene id: 1085623:GNIT_RS04190
uniprot id: G4QJX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS13965
gene id: 1085623:GNIT_RS13965
uniprot id: G4QMV3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS06625
gene id: 1085623:GNIT_RS06625
uniprot id: G4QL42
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1085623:GNIT RS09170
gene id: 1085623:GNIT_RS09170
uniprot id: G4QKH1
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1085623:GNIT RS14600
gene id: 1085623:GNIT_RS14600
uniprot id: G4QIL7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1085623:GNIT RS05305
gene id: 1085623:GNIT_RS05305
uniprot id: G4QG81
names: Similarity
messages: Belongs to the MotB family.

1085623:GNIT RS08150
gene id: 1085623:GNIT_RS08150
uniprot id: G4QLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1085623:GNIT RS16850
gene id: 1085623:GNIT_RS16850
uniprot id: G4QNU5
names: Similarity
messages: Belongs to the SCO1/2 family.

1085623:GNIT RS05815
gene id: 1085623:GNIT_RS05815
uniprot id: G4QKW2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1085623:GNIT RS03655
gene id: 1085623:GNIT_RS03655
uniprot id: G4QJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1085623:GNIT RS14265
gene id: 1085623:GNIT_RS14265
uniprot id: G4QDS5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1085623:GNIT RS04690
gene id: 1085623:GNIT_RS04690
uniprot id: G4QK02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS07325
gene id: 1085623:GNIT_RS07325
uniprot id: G4QGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1085623:GNIT RS12565
gene id: 1085623:GNIT_RS12565
uniprot id: G4QM89
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1085623:GNIT RS05645
gene id: 1085623:GNIT_RS05645
uniprot id: G4QKB6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1085623:GNIT RS10440
gene id: 1085623:GNIT_RS10440
uniprot id: G4QHR7
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS12390
gene id: 1085623:GNIT_RS12390
uniprot id: G4QI91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1085623:GNIT RS03270
gene id: 1085623:GNIT_RS03270
uniprot id: G4QFP2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1085623:GNIT RS11900
gene id: 1085623:GNIT_RS11900
uniprot id: G4QM27
names: Similarity
messages: Belongs to the type III secretion exporter family.

1085623:GNIT RS09070
gene id: 1085623:GNIT_RS09070
uniprot id: G4QKE9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1085623:GNIT RS13020
gene id: 1085623:GNIT_RS13020
uniprot id: G4QIC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1085623:GNIT RS07990
gene id: 1085623:GNIT_RS07990
uniprot id: G4QLD1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS11015
gene id: 1085623:GNIT_RS11015
uniprot id: G4QLS3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1085623:GNIT RS03350
gene id: 1085623:GNIT_RS03350
uniprot id: G4QFQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1085623:GNIT RS01820
gene id: 1085623:GNIT_RS01820
uniprot id: G4QJD1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1085623:GNIT RS13325
gene id: 1085623:GNIT_RS13325
uniprot id: G4QII6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1085623:GNIT RS11355
gene id: 1085623:GNIT_RS11355
uniprot id: G4QLZ0
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

1085623:GNIT RS01405
gene id: 1085623:GNIT_RS01405
uniprot id: G4QFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1085623:GNIT RS12975
gene id: 1085623:GNIT_RS12975
uniprot id: G4QMQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS04075
gene id: 1085623:GNIT_RS04075
uniprot id: G4QJV3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS07720
gene id: 1085623:GNIT_RS07720
uniprot id: G4QHB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1085623:GNIT RS08265
gene id: 1085623:GNIT_RS08265
uniprot id: G4QLI4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1085623:GNIT RS11000
gene id: 1085623:GNIT_RS11000
uniprot id: G4QLS0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1085623:GNIT RS03135
gene id: 1085623:GNIT_RS03135
uniprot id: G4QFM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1085623:GNIT RS13175
gene id: 1085623:GNIT_RS13175
uniprot id: G4QIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS16565
gene id: 1085623:GNIT_RS16565
uniprot id: G4QNN3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13620
gene id: 1085623:GNIT_RS13620
uniprot id: G4QML1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1085623:GNIT RS17115
gene id: 1085623:GNIT_RS17115
uniprot id: G4QNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1085623:GNIT RS04245
gene id: 1085623:GNIT_RS04245
uniprot id: G4QJY8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS15855
gene id: 1085623:GNIT_RS15855
uniprot id: G4QN22
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1085623:GNIT RS04215
gene id: 1085623:GNIT_RS04215
uniprot id: G4QJY2
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1085623:GNIT RS08215
gene id: 1085623:GNIT_RS08215
uniprot id: G4QLH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1085623:GNIT RS05485
gene id: 1085623:GNIT_RS05485
uniprot id: G4QK80
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS15925
gene id: 1085623:GNIT_RS15925
uniprot id: G4QN37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS12330
gene id: 1085623:GNIT_RS12330
uniprot id: G4QI77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS13850
gene id: 1085623:GNIT_RS13850
uniprot id: G4QMT0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1085623:GNIT RS12295
gene id: 1085623:GNIT_RS12295
uniprot id: G4QI69
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13905
gene id: 1085623:GNIT_RS13905
uniprot id: G4QMU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1085623:GNIT RS00665
gene id: 1085623:GNIT_RS00665
uniprot id: G4QIV4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1085623:GNIT RS13665
gene id: 1085623:GNIT_RS13665
uniprot id: G4QMM1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1085623:GNIT RS05650
gene id: 1085623:GNIT_RS05650
uniprot id: G4QKB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1085623:GNIT RS14080
gene id: 1085623:GNIT_RS14080
uniprot id: G4QMY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1085623:GNIT RS00450
gene id: 1085623:GNIT_RS00450
uniprot id: G4QEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS08205
gene id: 1085623:GNIT_RS08205
uniprot id: G4QLH2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1085623:GNIT RS08085
gene id: 1085623:GNIT_RS08085
uniprot id: G4QLF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1085623:GNIT RS05180
gene id: 1085623:GNIT_RS05180
uniprot id: G4QG55
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1085623:GNIT RS10350
gene id: 1085623:GNIT_RS10350
uniprot id: G4QHP9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1085623:GNIT RS04220
gene id: 1085623:GNIT_RS04220
uniprot id: G4QJY3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1085623:GNIT RS09465
gene id: 1085623:GNIT_RS09465
uniprot id: G4QLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1085623:GNIT RS13690
gene id: 1085623:GNIT_RS13690
uniprot id: G4QMM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1085623:GNIT RS07935
gene id: 1085623:GNIT_RS07935
uniprot id: G4QLB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1085623:GNIT RS03455
gene id: 1085623:GNIT_RS03455
uniprot id: G4QFT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1085623:GNIT RS00935
gene id: 1085623:GNIT_RS00935
uniprot id: G4QF05
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1085623:GNIT RS05000
gene id: 1085623:GNIT_RS05000
uniprot id: G4QK63
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1085623:GNIT RS12840
gene id: 1085623:GNIT_RS12840
uniprot id: G4QME6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS06170
gene id: 1085623:GNIT_RS06170
uniprot id: G4QGA0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1085623:GNIT RS05365
gene id: 1085623:GNIT_RS05365
uniprot id: G4QG93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1085623:GNIT RS10125
gene id: 1085623:GNIT_RS10125
uniprot id: G4QH46
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS01285
gene id: 1085623:GNIT_RS01285
uniprot id: G4QF80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1085623:GNIT RS14275
gene id: 1085623:GNIT_RS14275
uniprot id: G4QDS7
names: Similarity
messages: Belongs to the peptidase U62 family.

1085623:GNIT RS05820
gene id: 1085623:GNIT_RS05820
uniprot id: G4QKW3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS03460
gene id: 1085623:GNIT_RS03460
uniprot id: G4QFT2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1085623:GNIT RS00105
gene id: 1085623:GNIT_RS00105
uniprot id: G4QEF5
names: Similarity
messages: Belongs to the DprA/Smf family.

1085623:GNIT RS05175
gene id: 1085623:GNIT_RS05175
uniprot id: G4QG54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1085623:GNIT RS08255
gene id: 1085623:GNIT_RS08255
uniprot id: G4QLI2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1085623:GNIT RS06875
gene id: 1085623:GNIT_RS06875
uniprot id: G4QL95
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS03160
gene id: 1085623:GNIT_RS03160
uniprot id: G4QFM8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1085623:GNIT RS10305
gene id: 1085623:GNIT_RS10305
uniprot id: G4QHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1085623:GNIT RS12465
gene id: 1085623:GNIT_RS12465
uniprot id: G4QIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS10050
gene id: 1085623:GNIT_RS10050
uniprot id: G4QH30
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1085623:GNIT RS02350
gene id: 1085623:GNIT_RS02350
uniprot id: G4QJJ1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1085623:GNIT RS02905
gene id: 1085623:GNIT_RS02905
uniprot id: G4QEK0
names: Similarity
messages: Belongs to the thioredoxin family.

1085623:GNIT RS10965
gene id: 1085623:GNIT_RS10965
uniprot id: G4QKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1085623:GNIT RS16460
gene id: 1085623:GNIT_RS16460
uniprot id: G4QNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1085623:GNIT RS08440
gene id: 1085623:GNIT_RS08440
uniprot id: G4QGU1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1085623:GNIT RS13800
gene id: 1085623:GNIT_RS13800
uniprot id: G4QMR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1085623:GNIT RS09055
gene id: 1085623:GNIT_RS09055
uniprot id: G4QKE6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1085623:GNIT RS10215
gene id: 1085623:GNIT_RS10215
uniprot id: G4QHM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1085623:GNIT RS04605
gene id: 1085623:GNIT_RS04605
uniprot id: G4QG16
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS04990
gene id: 1085623:GNIT_RS04990
uniprot id: G4QK61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1085623:GNIT RS05585
gene id: 1085623:GNIT_RS05585
uniprot id: G4QKA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1085623:GNIT RS02800
gene id: 1085623:GNIT_RS02800
uniprot id: G4QEI1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS11945
gene id: 1085623:GNIT_RS11945
uniprot id: G4QM36
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS14965
gene id: 1085623:GNIT_RS14965
uniprot id: G4QDX6
names: Similarity
messages: Belongs to the citrate synthase family.

1085623:GNIT RS02690
gene id: 1085623:GNIT_RS02690
uniprot id: G4QJR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1085623:GNIT RS13730
gene id: 1085623:GNIT_RS13730
uniprot id: G4QMN4
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1085623:GNIT RS12470
gene id: 1085623:GNIT_RS12470
uniprot id: G4QIA8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1085623:GNIT RS14345
gene id: 1085623:GNIT_RS14345
uniprot id: G4QDU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS11545
gene id: 1085623:GNIT_RS11545
uniprot id: G4QHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1085623:GNIT RS00020
gene id: 1085623:GNIT_RS00020
uniprot id: G4QED6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1085623:GNIT RS02930
gene id: 1085623:GNIT_RS02930
uniprot id: G4QEK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS04895
gene id: 1085623:GNIT_RS04895
uniprot id: G4QK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1085623:GNIT RS14910
gene id: 1085623:GNIT_RS14910
uniprot id: G4QJ95
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1085623:GNIT RS07775
gene id: 1085623:GNIT_RS07775
uniprot id: G4QHC2
names: Similarity
messages: Belongs to the ArsC family.

1085623:GNIT RS14400
gene id: 1085623:GNIT_RS14400
uniprot id: G4QDV3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1085623:GNIT RS09830
gene id: 1085623:GNIT_RS09830
uniprot id: G4QLR7
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1085623:GNIT RS13810
gene id: 1085623:GNIT_RS13810
uniprot id: G4QMS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1085623:GNIT RS03090
gene id: 1085623:GNIT_RS03090
uniprot id: G4QEN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1085623:GNIT RS06100
gene id: 1085623:GNIT_RS06100
uniprot id: G4QL22
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1085623:GNIT RS05360
gene id: 1085623:GNIT_RS05360
uniprot id: G4QG92
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1085623:GNIT RS04130
gene id: 1085623:GNIT_RS04130
uniprot id: G4QJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS02485
gene id: 1085623:GNIT_RS02485
uniprot id: G4QJL8
names: Similarity
messages: Belongs to the SfsA family.

1085623:GNIT RS10895
gene id: 1085623:GNIT_RS10895
uniprot id: G4QKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1085623:GNIT RS08125
gene id: 1085623:GNIT_RS08125
uniprot id: G4QLF8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1085623:GNIT RS11635
gene id: 1085623:GNIT_RS11635
uniprot id: G4QI08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1085623:GNIT RS15030
gene id: 1085623:GNIT_RS15030
uniprot id: G4QDY9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS13065
gene id: 1085623:GNIT_RS13065
uniprot id: G4QID2
names: Similarity
messages: Belongs to the UPF0246 family.

1085623:GNIT RS10950
gene id: 1085623:GNIT_RS10950
uniprot id: G4QKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1085623:GNIT RS13510
gene id: 1085623:GNIT_RS13510
uniprot id: G4QMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1085623:GNIT RS10340
gene id: 1085623:GNIT_RS10340
uniprot id: G4QHP7
names: PTM
messages: Binds 1 heme group per subunit.

1085623:GNIT RS05530
gene id: 1085623:GNIT_RS05530
uniprot id: G4QK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS17095
gene id: 1085623:GNIT_RS17095
uniprot id: G4QNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS05140
gene id: 1085623:GNIT_RS05140
uniprot id: G4QG47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

1085623:GNIT RS05765
gene id: 1085623:GNIT_RS05765
uniprot id: G4QKE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1085623:GNIT RS08425
gene id: 1085623:GNIT_RS08425
uniprot id: G4QGT7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1085623:GNIT RS04880
gene id: 1085623:GNIT_RS04880
uniprot id: G4QK42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1085623:GNIT RS10420
gene id: 1085623:GNIT_RS10420
uniprot id: G4QHR3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS16360
gene id: 1085623:GNIT_RS16360
uniprot id: G4QND0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1085623:GNIT RS07900
gene id: 1085623:GNIT_RS07900
uniprot id: G4QLB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS17570
gene id: 1085623:GNIT_RS17570
uniprot id: G4QNK5
names: Similarity
messages: Belongs to the UPF0234 family.

1085623:GNIT RS00010
gene id: 1085623:GNIT_RS00010
uniprot id: G4QED4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1085623:GNIT RS10200
gene id: 1085623:GNIT_RS10200
uniprot id: G4QH63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1085623:GNIT RS01990
gene id: 1085623:GNIT_RS01990
uniprot id: G4QJH0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1085623:GNIT RS12275
gene id: 1085623:GNIT_RS12275
uniprot id: G4QI65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1085623:GNIT RS06990
gene id: 1085623:GNIT_RS06990
uniprot id: G4QEQ1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS04640
gene id: 1085623:GNIT_RS04640
uniprot id: G4QJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1085623:GNIT RS01910
gene id: 1085623:GNIT_RS01910
uniprot id: G4QJF1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1085623:GNIT RS13805
gene id: 1085623:GNIT_RS13805
uniprot id: G4QMS0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1085623:GNIT RS11880
gene id: 1085623:GNIT_RS11880
uniprot id: G4QM23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1085623:GNIT RS10040
gene id: 1085623:GNIT_RS10040
uniprot id: G4QH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1085623:GNIT RS16300
gene id: 1085623:GNIT_RS16300
uniprot id: G4QNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1085623:GNIT RS11815
gene id: 1085623:GNIT_RS11815
uniprot id: G4QM09
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1085623:GNIT RS09490
gene id: 1085623:GNIT_RS09490
uniprot id: G4QLJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1085623:GNIT RS04915
gene id: 1085623:GNIT_RS04915
uniprot id: G4QK50
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1085623:GNIT RS13050
gene id: 1085623:GNIT_RS13050
uniprot id: G4QIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1085623:GNIT RS16425
gene id: 1085623:GNIT_RS16425
uniprot id: G4QNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1085623:GNIT RS15060
gene id: 1085623:GNIT_RS15060
uniprot id: G4QDZ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1085623:GNIT RS04790
gene id: 1085623:GNIT_RS04790
uniprot id: G4QK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1085623:GNIT RS10315
gene id: 1085623:GNIT_RS10315
uniprot id: G4QHP2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS07925
gene id: 1085623:GNIT_RS07925
uniprot id: G4QLB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1085623:GNIT RS12955
gene id: 1085623:GNIT_RS12955
uniprot id: G4QMQ3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1085623:GNIT RS15315
gene id: 1085623:GNIT_RS15315
uniprot id: G4QE48
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1085623:GNIT RS03095
gene id: 1085623:GNIT_RS03095
uniprot id: G4QEN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1085623:GNIT RS05235
gene id: 1085623:GNIT_RS05235
uniprot id: G4QG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS11550
gene id: 1085623:GNIT_RS11550
uniprot id: G4QHY7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1085623:GNIT RS06710
gene id: 1085623:GNIT_RS06710
uniprot id: G4QL59
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS00075
gene id: 1085623:GNIT_RS00075
uniprot id: G4QEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1085623:GNIT RS14270
gene id: 1085623:GNIT_RS14270
uniprot id: G4QDS6
names: Similarity
messages: Belongs to the peptidase U62 family.

1085623:GNIT RS03110
gene id: 1085623:GNIT_RS03110
uniprot id: G4QEP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1085623:GNIT RS13725
gene id: 1085623:GNIT_RS13725
uniprot id: G4QMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1085623:GNIT RS03855
gene id: 1085623:GNIT_RS03855
uniprot id: G4QJ87
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1085623:GNIT RS16325
gene id: 1085623:GNIT_RS16325
uniprot id: G4QNC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1085623:GNIT RS07120
gene id: 1085623:GNIT_RS07120
uniprot id: G4QES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS14450
gene id: 1085623:GNIT_RS14450
uniprot id: G4QDW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1085623:GNIT RS03575
gene id: 1085623:GNIT_RS03575
uniprot id: G4QJ23
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1085623:GNIT RS15655
gene id: 1085623:GNIT_RS15655
uniprot id: G4QEC1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS00195
gene id: 1085623:GNIT_RS00195
uniprot id: G4QET2
names: Similarity
messages: Belongs to the RecA family.

1085623:GNIT RS17160
gene id: 1085623:GNIT_RS17160
uniprot id: G4QP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085623:GNIT RS12690
gene id: 1085623:GNIT_RS12690
uniprot id: G4QMB6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1085623:GNIT RS02770
gene id: 1085623:GNIT_RS02770
uniprot id: G4QEH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1085623:GNIT RS05230
gene id: 1085623:GNIT_RS05230
uniprot id: G4QG66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1085623:GNIT RS00015
gene id: 1085623:GNIT_RS00015
uniprot id: G4QED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1085623:GNIT RS09200
gene id: 1085623:GNIT_RS09200
uniprot id: G4QKH8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1085623:GNIT RS03060
gene id: 1085623:GNIT_RS03060
uniprot id: G4QEN0
names: Subcellular Location Annotation
messages: Secreted

1085623:GNIT RS00315
gene id: 1085623:GNIT_RS00315
uniprot id: G4QEV8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS15835
gene id: 1085623:GNIT_RS15835
uniprot id: G4QN18
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1085623:GNIT RS14890
gene id: 1085623:GNIT_RS14890
uniprot id: G4QJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1085623:GNIT RS06825
gene id: 1085623:GNIT_RS06825
uniprot id: G4QL85
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

1085623:GNIT RS12640
gene id: 1085623:GNIT_RS12640
uniprot id: G4QMA5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1085623:GNIT RS00975
gene id: 1085623:GNIT_RS00975
uniprot id: G4QF14
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1085623:GNIT RS13985
gene id: 1085623:GNIT_RS13985
uniprot id: G4QMV8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1085623:GNIT RS08455
gene id: 1085623:GNIT_RS08455
uniprot id: G4QGU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS06855
gene id: 1085623:GNIT_RS06855
uniprot id: G4QL91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS16575
gene id: 1085623:GNIT_RS16575
uniprot id: G4QNN5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1085623:GNIT RS10145
gene id: 1085623:GNIT_RS10145
uniprot id: G4QH51
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1085623:GNIT RS02885
gene id: 1085623:GNIT_RS02885
uniprot id: G4QEJ6
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1085623:GNIT RS16770
gene id: 1085623:GNIT_RS16770
uniprot id: G4QNS7
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS16980
gene id: 1085623:GNIT_RS16980
uniprot id: G4QNX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1085623:GNIT RS05720
gene id: 1085623:GNIT_RS05720
uniprot id: G4QKD4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1085623:GNIT RS14960
gene id: 1085623:GNIT_RS14960
uniprot id: G4QDX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1085623:GNIT RS02625
gene id: 1085623:GNIT_RS02625
uniprot id: G4QJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1085623:GNIT RS07915
gene id: 1085623:GNIT_RS07915
uniprot id: G4QLB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS07570
gene id: 1085623:GNIT_RS07570
uniprot id: G4QH81
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1085623:GNIT RS09665
gene id: 1085623:GNIT_RS09665
uniprot id: G4QLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS06445
gene id: 1085623:GNIT_RS06445
uniprot id: G4QGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1085623:GNIT RS12150
gene id: 1085623:GNIT_RS12150
uniprot id: G4QI39
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09345
gene id: 1085623:GNIT_RS09345
uniprot id: G4QKK8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1085623:GNIT RS09920
gene id: 1085623:GNIT_RS09920
uniprot id: G4QH04
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1085623:GNIT RS02990
gene id: 1085623:GNIT_RS02990
uniprot id: G4QEL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1085623:GNIT RS05915
gene id: 1085623:GNIT_RS05915
uniprot id: G4QKY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1085623:GNIT RS14170
gene id: 1085623:GNIT_RS14170
uniprot id: G4QDQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS04695
gene id: 1085623:GNIT_RS04695
uniprot id: G4QK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1085623:GNIT RS06220
gene id: 1085623:GNIT_RS06220
uniprot id: G4QGB0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS11480
gene id: 1085623:GNIT_RS11480
uniprot id: G4QHX2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1085623:GNIT RS16450
gene id: 1085623:GNIT_RS16450
uniprot id: G4QNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS16745
gene id: 1085623:GNIT_RS16745
uniprot id: G4QNS1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1085623:GNIT RS07510
gene id: 1085623:GNIT_RS07510
uniprot id: G4QH66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1085623:GNIT RS14360
gene id: 1085623:GNIT_RS14360
uniprot id: G4QDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1085623:GNIT RS11675
gene id: 1085623:GNIT_RS11675
uniprot id: G4QI16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1085623:GNIT RS11950
gene id: 1085623:GNIT_RS11950
uniprot id: G4QM37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1085623:GNIT RS16910
gene id: 1085623:GNIT_RS16910
uniprot id: G4QNV8
names: Similarity
messages: Belongs to the peptidase S8 family.

1085623:GNIT RS01500
gene id: 1085623:GNIT_RS01500
uniprot id: G4QFC7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS12230
gene id: 1085623:GNIT_RS12230
uniprot id: G4QI56
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1085623:GNIT RS04645
gene id: 1085623:GNIT_RS04645
uniprot id: G4QJZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1085623:GNIT RS06995
gene id: 1085623:GNIT_RS06995
uniprot id: G4QEQ2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1085623:GNIT RS06435
gene id: 1085623:GNIT_RS06435
uniprot id: G4QGF4
names: Similarity
messages: Belongs to the peptidase S51 family.

1085623:GNIT RS12510
gene id: 1085623:GNIT_RS12510
uniprot id: G4QM78
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1085623:GNIT RS17330
gene id: 1085623:GNIT_RS17330
uniprot id: G4QNF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1085623:GNIT RS07870
gene id: 1085623:GNIT_RS07870
uniprot id: G4QHE2
names: Caution
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS03325
gene id: 1085623:GNIT_RS03325
uniprot id: G4QFQ4
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1085623:GNIT RS03125
gene id: 1085623:GNIT_RS03125
uniprot id: G4QFM1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1085623:GNIT RS12930
gene id: 1085623:GNIT_RS12930
uniprot id: G4QMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1085623:GNIT RS08465
gene id: 1085623:GNIT_RS08465
uniprot id: G4QGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1085623:GNIT RS18355
gene id: 1085623:GNIT_RS18355
uniprot id: G4QK85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1085623:GNIT RS00275
gene id: 1085623:GNIT_RS00275
uniprot id: G4QEV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1085623:GNIT RS16370
gene id: 1085623:GNIT_RS16370
uniprot id: G4QND3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1085623:GNIT RS11405
gene id: 1085623:GNIT_RS11405
uniprot id: G4QHV7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1085623:GNIT RS09590
gene id: 1085623:GNIT_RS09590
uniprot id: G4QLL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1085623:GNIT RS00655
gene id: 1085623:GNIT_RS00655
uniprot id: G4QIV2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1085623:GNIT RS03005
gene id: 1085623:GNIT_RS03005
uniprot id: G4QEL9
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS04370
gene id: 1085623:GNIT_RS04370
uniprot id: G4QFW4
names: Similarity
messages: Belongs to the histone deacetylase family.

1085623:GNIT RS00515
gene id: 1085623:GNIT_RS00515
uniprot id: G4QEZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS05580
gene id: 1085623:GNIT_RS05580
uniprot id: G4QKA1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1085623:GNIT RS10120
gene id: 1085623:GNIT_RS10120
uniprot id: G4QH45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1085623:GNIT RS08340
gene id: 1085623:GNIT_RS08340
uniprot id: G4QGS0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1085623:GNIT RS13815
gene id: 1085623:GNIT_RS13815
uniprot id: G4QMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1085623:GNIT RS14585
gene id: 1085623:GNIT_RS14585
uniprot id: G4QIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS09545
gene id: 1085623:GNIT_RS09545
uniprot id: G4QLK8
names: Similarity
messages: Belongs to the peptidase S49 family.

1085623:GNIT RS14420
gene id: 1085623:GNIT_RS14420
uniprot id: G4QFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1085623:GNIT RS05265
gene id: 1085623:GNIT_RS05265
uniprot id: G4QG73
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1085623:GNIT RS10230
gene id: 1085623:GNIT_RS10230
uniprot id: G4QHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1085623:GNIT RS07930
gene id: 1085623:GNIT_RS07930
uniprot id: G4QLB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1085623:GNIT RS16335
gene id: 1085623:GNIT_RS16335
uniprot id: G4QNC3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1085623:GNIT RS09875
gene id: 1085623:GNIT_RS09875
uniprot id: G4QGZ5
names: Similarity
messages: Belongs to the peptidase S16 family.

1085623:GNIT RS05570
gene id: 1085623:GNIT_RS05570
uniprot id: G4QK99
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1085623:GNIT RS12715
gene id: 1085623:GNIT_RS12715
uniprot id: G4QMC1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1085623:GNIT RS00545
gene id: 1085623:GNIT_RS00545
uniprot id: G4QIS9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1085623:GNIT RS12965
gene id: 1085623:GNIT_RS12965
uniprot id: G4QMQ5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1085623:GNIT RS07740
gene id: 1085623:GNIT_RS07740
uniprot id: G4QHB4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1085623:GNIT RS16260
gene id: 1085623:GNIT_RS16260
uniprot id: G4QNA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS06540
gene id: 1085623:GNIT_RS06540
uniprot id: G4QGH5
names: Similarity
messages: Belongs to the HesB/IscA family.

1085623:GNIT RS06750
gene id: 1085623:GNIT_RS06750
uniprot id: G4QL68
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1085623:GNIT RS16855
gene id: 1085623:GNIT_RS16855
uniprot id: G4QNU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1085623:GNIT RS10480
gene id: 1085623:GNIT_RS10480
uniprot id: G4QHS6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS03550
gene id: 1085623:GNIT_RS03550
uniprot id: G4QJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1085623:GNIT RS12820
gene id: 1085623:GNIT_RS12820
uniprot id: G4QME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1085623:GNIT RS16535
gene id: 1085623:GNIT_RS16535
uniprot id: G4QNM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1085623:GNIT RS12940
gene id: 1085623:GNIT_RS12940
uniprot id: G4QMQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS05300
gene id: 1085623:GNIT_RS05300
uniprot id: G4QG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1085623:GNIT RS00430
gene id: 1085623:GNIT_RS00430
uniprot id: G4QEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1085623:GNIT RS18360
gene id: 1085623:GNIT_RS18360
uniprot id: G4QK86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1085623:GNIT RS13095
gene id: 1085623:GNIT_RS13095
uniprot id: G4QID8
names: Similarity
messages: Belongs to the threonine synthase family.

1085623:GNIT RS01675
gene id: 1085623:GNIT_RS01675
uniprot id: G4QFG4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1085623:GNIT RS16570
gene id: 1085623:GNIT_RS16570
uniprot id: G4QNN4
names: Similarity
messages: Belongs to the UPF0270 family.

1085623:GNIT RS17510
gene id: 1085623:GNIT_RS17510
uniprot id: G4QNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1085623:GNIT RS10545
gene id: 1085623:GNIT_RS10545
uniprot id: G4QHU0
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS06905
gene id: 1085623:GNIT_RS06905
uniprot id: G4QLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1085623:GNIT RS14680
gene id: 1085623:GNIT_RS14680
uniprot id: G4QIN5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1085623:GNIT RS01845
gene id: 1085623:GNIT_RS01845
uniprot id: G4QJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1085623:GNIT RS15805
gene id: 1085623:GNIT_RS15805
uniprot id: G4QN11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS09895
gene id: 1085623:GNIT_RS09895
uniprot id: G4QGZ9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1085623:GNIT RS03145
gene id: 1085623:GNIT_RS03145
uniprot id: G4QFM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1085623:GNIT RS03875
gene id: 1085623:GNIT_RS03875
uniprot id: G4QJR8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS12310
gene id: 1085623:GNIT_RS12310
uniprot id: G4QI72
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS03485
gene id: 1085623:GNIT_RS03485
uniprot id: G4QFT7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1085623:GNIT RS12575
gene id: 1085623:GNIT_RS12575
uniprot id: G4QM92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1085623:GNIT RS01545
gene id: 1085623:GNIT_RS01545
uniprot id: G4QFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1085623:GNIT RS01760
gene id: 1085623:GNIT_RS01760
uniprot id: G4QJB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1085623:GNIT RS07070
gene id: 1085623:GNIT_RS07070
uniprot id: G4QER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1085623:GNIT RS12825
gene id: 1085623:GNIT_RS12825
uniprot id: G4QME3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1085623:GNIT RS00505
gene id: 1085623:GNIT_RS00505
uniprot id: G4QEZ7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1085623:GNIT RS06530
gene id: 1085623:GNIT_RS06530
uniprot id: G4QGH3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1085623:GNIT RS02255
gene id: 1085623:GNIT_RS02255
uniprot id: G4QFK7
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1085623:GNIT RS02345
gene id: 1085623:GNIT_RS02345
uniprot id: G4QJJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1085623:GNIT RS11190
gene id: 1085623:GNIT_RS11190
uniprot id: G4QLV6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1085623:GNIT RS15155
gene id: 1085623:GNIT_RS15155
uniprot id: G4QE15
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS04240
gene id: 1085623:GNIT_RS04240
uniprot id: G4QJY7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1085623:GNIT RS16275
gene id: 1085623:GNIT_RS16275
uniprot id: G4QNB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS05495
gene id: 1085623:GNIT_RS05495
uniprot id: G4QK82
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS04360
gene id: 1085623:GNIT_RS04360
uniprot id: G4QFW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS04280
gene id: 1085623:GNIT_RS04280
uniprot id: G4QFU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS00660
gene id: 1085623:GNIT_RS00660
uniprot id: G4QIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS05105
gene id: 1085623:GNIT_RS05105
uniprot id: G4QG40
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1085623:GNIT RS03130
gene id: 1085623:GNIT_RS03130
uniprot id: G4QFM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1085623:GNIT RS17545
gene id: 1085623:GNIT_RS17545
uniprot id: G4QNJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1085623:GNIT RS17520
gene id: 1085623:GNIT_RS17520
uniprot id: G4QNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1085623:GNIT RS12245
gene id: 1085623:GNIT_RS12245
uniprot id: G4QI59
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1085623:GNIT RS03620
gene id: 1085623:GNIT_RS03620
uniprot id: G4QJ33
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1085623:GNIT RS02615
gene id: 1085623:GNIT_RS02615
uniprot id: G4QJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1085623:GNIT RS10640
gene id: 1085623:GNIT_RS10640
uniprot id: G4QKN4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1085623:GNIT RS10360
gene id: 1085623:GNIT_RS10360
uniprot id: G4QHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1085623:GNIT RS06980
gene id: 1085623:GNIT_RS06980
uniprot id: G4QEP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS12850
gene id: 1085623:GNIT_RS12850
uniprot id: G4QME8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1085623:GNIT RS09175
gene id: 1085623:GNIT_RS09175
uniprot id: G4QKH2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1085623:GNIT RS04845
gene id: 1085623:GNIT_RS04845
uniprot id: G4QK35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1085623:GNIT RS16355
gene id: 1085623:GNIT_RS16355
uniprot id: G4QNC9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1085623:GNIT RS03525
gene id: 1085623:GNIT_RS03525
uniprot id: G4QJ13
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1085623:GNIT RS03530
gene id: 1085623:GNIT_RS03530
uniprot id: G4QJ14
names: Similarity
messages: Belongs to the UPF0102 family.

1085623:GNIT RS02065
gene id: 1085623:GNIT_RS02065
uniprot id: G4QFG7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1085623:GNIT RS12360
gene id: 1085623:GNIT_RS12360
uniprot id: G4QI85
names: Similarity
messages: Belongs to the UPF0047 family.

1085623:GNIT RS02855
gene id: 1085623:GNIT_RS02855
uniprot id: G4QEJ0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1085623:GNIT RS06810
gene id: 1085623:GNIT_RS06810
uniprot id: G4QL82
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1085623:GNIT RS16420
gene id: 1085623:GNIT_RS16420
uniprot id: G4QNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1085623:GNIT RS16000
gene id: 1085623:GNIT_RS16000
uniprot id: G4QN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS01595
gene id: 1085623:GNIT_RS01595
uniprot id: G4QFE8
names: Similarity
messages: Belongs to the GSP E family.

1085623:GNIT RS00675
gene id: 1085623:GNIT_RS00675
uniprot id: G4QIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1085623:GNIT RS02955
gene id: 1085623:GNIT_RS02955
uniprot id: G4QEK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13420
gene id: 1085623:GNIT_RS13420
uniprot id: G4QMG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1085623:GNIT RS03475
gene id: 1085623:GNIT_RS03475
uniprot id: G4QFT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1085623:GNIT RS14920
gene id: 1085623:GNIT_RS14920
uniprot id: G4QJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1085623:GNIT RS11515
gene id: 1085623:GNIT_RS11515
uniprot id: G4QHY0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1085623:GNIT RS11065
gene id: 1085623:GNIT_RS11065
uniprot id: G4QLT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1085623:GNIT RS01295
gene id: 1085623:GNIT_RS01295
uniprot id: G4QF82
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1085623:GNIT RS01750
gene id: 1085623:GNIT_RS01750
uniprot id: G4QJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1085623:GNIT RS01225
gene id: 1085623:GNIT_RS01225
uniprot id: G4QF66
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1085623:GNIT RS12070
gene id: 1085623:GNIT_RS12070
uniprot id: G4QM64
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1085623:GNIT RS01230
gene id: 1085623:GNIT_RS01230
uniprot id: G4QF67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1085623:GNIT RS09500
gene id: 1085623:GNIT_RS09500
uniprot id: G4QLJ9
names: Similarity
messages: Belongs to the HIBADH-related family.

1085623:GNIT RS02895
gene id: 1085623:GNIT_RS02895
uniprot id: G4QEJ8
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

1085623:GNIT RS16465
gene id: 1085623:GNIT_RS16465
uniprot id: G4QNL3
names: Similarity
messages: Belongs to the GSP N family.

1085623:GNIT RS05560
gene id: 1085623:GNIT_RS05560
uniprot id: G4QK96
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1085623:GNIT RS10390
gene id: 1085623:GNIT_RS10390
uniprot id: G4QHQ7
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13400
gene id: 1085623:GNIT_RS13400
uniprot id: G4QMG3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1085623:GNIT RS16485
gene id: 1085623:GNIT_RS16485
uniprot id: G4QNL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1085623:GNIT RS12200
gene id: 1085623:GNIT_RS12200
uniprot id: G4QI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1085623:GNIT RS09530
gene id: 1085623:GNIT_RS09530
uniprot id: G4QLK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS00445
gene id: 1085623:GNIT_RS00445
uniprot id: G4QEY5
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1085623:GNIT RS03660
gene id: 1085623:GNIT_RS03660
uniprot id: G4QJ43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1085623:GNIT RS11555
gene id: 1085623:GNIT_RS11555
uniprot id: G4QHY8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1085623:GNIT RS13105
gene id: 1085623:GNIT_RS13105
uniprot id: G4QIE0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1085623:GNIT RS08450
gene id: 1085623:GNIT_RS08450
uniprot id: G4QGU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1085623:GNIT RS02575
gene id: 1085623:GNIT_RS02575
uniprot id: G4QJN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS04290
gene id: 1085623:GNIT_RS04290
uniprot id: G4QFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1085623:GNIT RS08330
gene id: 1085623:GNIT_RS08330
uniprot id: G4QGR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1085623:GNIT RS05440
gene id: 1085623:GNIT_RS05440
uniprot id: G4QK71
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1085623:GNIT RS12625
gene id: 1085623:GNIT_RS12625
uniprot id: G4QMA2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1085623:GNIT RS09975
gene id: 1085623:GNIT_RS09975
uniprot id: G4QH15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS12795
gene id: 1085623:GNIT_RS12795
uniprot id: G4QMD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

1085623:GNIT RS17255
gene id: 1085623:GNIT_RS17255
uniprot id: G4QP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1085623:GNIT RS06345
gene id: 1085623:GNIT_RS06345
uniprot id: G4QGD6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1085623:GNIT RS01035
gene id: 1085623:GNIT_RS01035
uniprot id: G4QF28
names: Similarity
messages: Belongs to the creatininase superfamily.

1085623:GNIT RS02280
gene id: 1085623:GNIT_RS02280
uniprot id: G4QFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1085623:GNIT RS14190
gene id: 1085623:GNIT_RS14190
uniprot id: G4QDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS09795
gene id: 1085623:GNIT_RS09795
uniprot id: G4QLR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS17100
gene id: 1085623:GNIT_RS17100
uniprot id: G4QNZ6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1085623:GNIT RS05225
gene id: 1085623:GNIT_RS05225
uniprot id: G4QG65
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1085623:GNIT RS14175
gene id: 1085623:GNIT_RS14175
uniprot id: G4QDQ4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1085623:GNIT RS10205
gene id: 1085623:GNIT_RS10205
uniprot id: G4QH64
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1085623:GNIT RS06015
gene id: 1085623:GNIT_RS06015
uniprot id: G4QL04
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1085623:GNIT RS13930
gene id: 1085623:GNIT_RS13930
uniprot id: G4QMU6
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1085623:GNIT RS09295
gene id: 1085623:GNIT_RS09295
uniprot id: G4QKJ8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1085623:GNIT RS02560
gene id: 1085623:GNIT_RS02560
uniprot id: G4QJN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS03320
gene id: 1085623:GNIT_RS03320
uniprot id: G4QFQ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS09090
gene id: 1085623:GNIT_RS09090
uniprot id: G4QKF3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS04145
gene id: 1085623:GNIT_RS04145
uniprot id: G4QJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS14000
gene id: 1085623:GNIT_RS14000
uniprot id: G4QMW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1085623:GNIT RS04920
gene id: 1085623:GNIT_RS04920
uniprot id: G4QK51
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1085623:GNIT RS12995
gene id: 1085623:GNIT_RS12995
uniprot id: G4QIB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS04650
gene id: 1085623:GNIT_RS04650
uniprot id: G4QJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

1085623:GNIT RS13750
gene id: 1085623:GNIT_RS13750
uniprot id: G4QMN8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS01255
gene id: 1085623:GNIT_RS01255
uniprot id: G4QF74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1085623:GNIT RS10005
gene id: 1085623:GNIT_RS10005
uniprot id: G4QH21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1085623:GNIT RS13890
gene id: 1085623:GNIT_RS13890
uniprot id: G4QMT8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1085623:GNIT RS00330
gene id: 1085623:GNIT_RS00330
uniprot id: G4QEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1085623:GNIT RS14445
gene id: 1085623:GNIT_RS14445
uniprot id: G4QDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1085623:GNIT RS00465
gene id: 1085623:GNIT_RS00465
uniprot id: G4QEY9
names: Similarity
messages: Belongs to the peptidase S33 family.

1085623:GNIT RS02105
gene id: 1085623:GNIT_RS02105
uniprot id: G4QFH5
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS11940
gene id: 1085623:GNIT_RS11940
uniprot id: G4QM35
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1085623:GNIT RS05870
gene id: 1085623:GNIT_RS05870
uniprot id: G4QKX3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1085623:GNIT RS12785
gene id: 1085623:GNIT_RS12785
uniprot id: G4QMD5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1085623:GNIT RS14575
gene id: 1085623:GNIT_RS14575
uniprot id: G4QIL2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1085623:GNIT RS03690
gene id: 1085623:GNIT_RS03690
uniprot id: G4QJ49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1085623:GNIT RS07525
gene id: 1085623:GNIT_RS07525
uniprot id: G4QH69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1085623:GNIT RS17055
gene id: 1085623:GNIT_RS17055
uniprot id: G4QNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS04020
gene id: 1085623:GNIT_RS04020
uniprot id: G4QJU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1085623:GNIT RS07755
gene id: 1085623:GNIT_RS07755
uniprot id: G4QHB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1085623:GNIT RS10450
gene id: 1085623:GNIT_RS10450
uniprot id: G4QHR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1085623:GNIT RS02075
gene id: 1085623:GNIT_RS02075
uniprot id: G4QFG9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS01800
gene id: 1085623:GNIT_RS01800
uniprot id: G4QJC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1085623:GNIT RS04100
gene id: 1085623:GNIT_RS04100
uniprot id: G4QJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1085623:GNIT RS03480
gene id: 1085623:GNIT_RS03480
uniprot id: G4QFT6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1085623:GNIT RS05100
gene id: 1085623:GNIT_RS05100
uniprot id: G4QG39
names: Similarity
messages: Belongs to the P(II) protein family.

1085623:GNIT RS02480
gene id: 1085623:GNIT_RS02480
uniprot id: G4QJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1085623:GNIT RS15880
gene id: 1085623:GNIT_RS15880
uniprot id: G4QN28
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS03890
gene id: 1085623:GNIT_RS03890
uniprot id: G4QJS1
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1085623:GNIT RS14435
gene id: 1085623:GNIT_RS14435
uniprot id: G4QDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1085623:GNIT RS13610
gene id: 1085623:GNIT_RS13610
uniprot id: G4QMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1085623:GNIT RS03465
gene id: 1085623:GNIT_RS03465
uniprot id: G4QFT3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1085623:GNIT RS02210
gene id: 1085623:GNIT_RS02210
uniprot id: G4QFJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS09700
gene id: 1085623:GNIT_RS09700
uniprot id: G4QLP1
names: Similarity
messages: Belongs to the pirin family.

1085623:GNIT RS12970
gene id: 1085623:GNIT_RS12970
uniprot id: G4QMQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS13935
gene id: 1085623:GNIT_RS13935
uniprot id: G4QMU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1085623:GNIT RS09620
gene id: 1085623:GNIT_RS09620
uniprot id: G4QLM4
names: Similarity
messages: Belongs to the universal stress protein A family.

1085623:GNIT RS17070
gene id: 1085623:GNIT_RS17070
uniprot id: G4QNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

1085623:GNIT RS00605
gene id: 1085623:GNIT_RS00605
uniprot id: G4QIU2
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1085623:GNIT RS11720
gene id: 1085623:GNIT_RS11720
uniprot id: G4QI26
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1085623:GNIT RS13040
gene id: 1085623:GNIT_RS13040
uniprot id: G4QIC7
names: Similarity
messages: Belongs to the GSP E family.

1085623:GNIT RS16190
gene id: 1085623:GNIT_RS16190
uniprot id: G4QN93
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS10195
gene id: 1085623:GNIT_RS10195
uniprot id: G4QH62
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1085623:GNIT RS10920
gene id: 1085623:GNIT_RS10920
uniprot id: G4QKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1085623:GNIT RS10810
gene id: 1085623:GNIT_RS10810
uniprot id: G4QKR7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1085623:GNIT RS02340
gene id: 1085623:GNIT_RS02340
uniprot id: G4QJI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1085623:GNIT RS00040
gene id: 1085623:GNIT_RS00040
uniprot id: G4QEE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1085623:GNIT RS05340
gene id: 1085623:GNIT_RS05340
uniprot id: G4QG88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS04235
gene id: 1085623:GNIT_RS04235
uniprot id: G4QJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1085623:GNIT RS09630
gene id: 1085623:GNIT_RS09630
uniprot id: G4QLM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1085623:GNIT RS02520
gene id: 1085623:GNIT_RS02520
uniprot id: G4QJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1085623:GNIT RS16380
gene id: 1085623:GNIT_RS16380
uniprot id: G4QND5
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1085623:GNIT RS02635
gene id: 1085623:GNIT_RS02635
uniprot id: G4QJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1085623:GNIT RS00420
gene id: 1085623:GNIT_RS00420
uniprot id: G4QEY0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1085623:GNIT RS03085
gene id: 1085623:GNIT_RS03085
uniprot id: G4QEN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1085623:GNIT RS10190
gene id: 1085623:GNIT_RS10190
uniprot id: G4QH61
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1085623:GNIT RS12460
gene id: 1085623:GNIT_RS12460
uniprot id: G4QIA6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1085623:GNIT RS15675
gene id: 1085623:GNIT_RS15675
uniprot id: G4QEC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1085623:GNIT RS17575
gene id: 1085623:GNIT_RS17575
uniprot id: G4QNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1085623:GNIT RS03150
gene id: 1085623:GNIT_RS03150
uniprot id: G4QFM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1085623:GNIT RS07000
gene id: 1085623:GNIT_RS07000
uniprot id: G4QEQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1085623:GNIT RS15640
gene id: 1085623:GNIT_RS15640
uniprot id: G4QEB7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1085623:GNIT RS12555
gene id: 1085623:GNIT_RS12555
uniprot id: G4QM87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS05375
gene id: 1085623:GNIT_RS05375
uniprot id: G4QG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1085623:GNIT RS04745
gene id: 1085623:GNIT_RS04745
uniprot id: G4QK15
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS10960
gene id: 1085623:GNIT_RS10960
uniprot id: G4QKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1085623:GNIT RS04710
gene id: 1085623:GNIT_RS04710
uniprot id: G4QK08
names: Cofactor
messages: Can also use Mn(2+) ion.

1085623:GNIT RS10715
gene id: 1085623:GNIT_RS10715
uniprot id: G4QKP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1085623:GNIT RS06880
gene id: 1085623:GNIT_RS06880
uniprot id: G4QL96
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS16165
gene id: 1085623:GNIT_RS16165
uniprot id: G4QN88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1085623:GNIT RS03045
gene id: 1085623:GNIT_RS03045
uniprot id: G4QEM7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1085623:GNIT RS11705
gene id: 1085623:GNIT_RS11705
uniprot id: G4QI22
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1085623:GNIT RS05255
gene id: 1085623:GNIT_RS05255
uniprot id: G4QG71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1085623:GNIT RS00125
gene id: 1085623:GNIT_RS00125
uniprot id: G4QEF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1085623:GNIT RS10235
gene id: 1085623:GNIT_RS10235
uniprot id: G4QHN0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1085623:GNIT RS01780
gene id: 1085623:GNIT_RS01780
uniprot id: G4QJC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1085623:GNIT RS05245
gene id: 1085623:GNIT_RS05245
uniprot id: G4QG69
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1085623:GNIT RS04945
gene id: 1085623:GNIT_RS04945
uniprot id: G4QK57
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1085623:GNIT RS10850
gene id: 1085623:GNIT_RS10850
uniprot id: G4QKS6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1085623:GNIT RS06885
gene id: 1085623:GNIT_RS06885
uniprot id: G4QL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS11180
gene id: 1085623:GNIT_RS11180
uniprot id: G4QLV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1085623:GNIT RS07940
gene id: 1085623:GNIT_RS07940
uniprot id: G4QLC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1085623:GNIT RS11100
gene id: 1085623:GNIT_RS11100
uniprot id: G4QLT7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1085623:GNIT RS17500
gene id: 1085623:GNIT_RS17500
uniprot id: G4QNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1085623:GNIT RS13290
gene id: 1085623:GNIT_RS13290
uniprot id: G4QIH9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1085623:GNIT RS10555
gene id: 1085623:GNIT_RS10555
uniprot id: G4QHU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1085623:GNIT RS12505
gene id: 1085623:GNIT_RS12505
uniprot id: G4QM77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS13010
gene id: 1085623:GNIT_RS13010
uniprot id: G4QIC0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1085623:GNIT RS02475
gene id: 1085623:GNIT_RS02475
uniprot id: G4QJL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1085623:GNIT RS05665
gene id: 1085623:GNIT_RS05665
uniprot id: G4QKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS04865
gene id: 1085623:GNIT_RS04865
uniprot id: G4QK39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1085623:GNIT RS16015
gene id: 1085623:GNIT_RS16015
uniprot id: G4QN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085623:GNIT RS01550
gene id: 1085623:GNIT_RS01550
uniprot id: G4QFE0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1085623:GNIT RS03900
gene id: 1085623:GNIT_RS03900
uniprot id: G4QJS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS07375
gene id: 1085623:GNIT_RS07375
uniprot id: G4QGN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS07575
gene id: 1085623:GNIT_RS07575
uniprot id: G4QH82
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1085623:GNIT RS11275
gene id: 1085623:GNIT_RS11275
uniprot id: G4QLX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1085623:GNIT RS00240
gene id: 1085623:GNIT_RS00240
uniprot id: G4QEU3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1085623:GNIT RS11645
gene id: 1085623:GNIT_RS11645
uniprot id: G4QI10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1085623:GNIT RS01220
gene id: 1085623:GNIT_RS01220
uniprot id: G4QF65
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1085623:GNIT RS13120
gene id: 1085623:GNIT_RS13120
uniprot id: G4QIE4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1085623:GNIT RS12740
gene id: 1085623:GNIT_RS12740
uniprot id: G4QMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1085623:GNIT RS07495
gene id: 1085623:GNIT_RS07495
uniprot id: G4QGQ7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1085623:GNIT RS02490
gene id: 1085623:GNIT_RS02490
uniprot id: G4QJL9
names: Similarity
messages: Belongs to the peptidase M17 family.

1085623:GNIT RS12735
gene id: 1085623:GNIT_RS12735
uniprot id: G4QMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1085623:GNIT RS05135
gene id: 1085623:GNIT_RS05135
uniprot id: G4QG46
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS09240
gene id: 1085623:GNIT_RS09240
uniprot id: G4QKI7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1085623:GNIT RS03210
gene id: 1085623:GNIT_RS03210
uniprot id: G4QFN4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1085623:GNIT RS15475
gene id: 1085623:GNIT_RS15475
uniprot id: G4QE82
names: Similarity
messages: Belongs to the GST superfamily.

1085623:GNIT RS05035
gene id: 1085623:GNIT_RS05035
uniprot id: G4QG26
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1085623:GNIT RS15920
gene id: 1085623:GNIT_RS15920
uniprot id: G4QN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1085623:GNIT RS05565
gene id: 1085623:GNIT_RS05565
uniprot id: G4QK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1085623:GNIT RS14650
gene id: 1085623:GNIT_RS14650
uniprot id: G4QIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1085623:GNIT RS14515
gene id: 1085623:GNIT_RS14515
uniprot id: G4QIJ9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1085623:GNIT RS11700
gene id: 1085623:GNIT_RS11700
uniprot id: G4QI21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1085623:GNIT RS13505
gene id: 1085623:GNIT_RS13505
uniprot id: G4QMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS08480
gene id: 1085623:GNIT_RS08480
uniprot id: G4QGV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS07955
gene id: 1085623:GNIT_RS07955
uniprot id: G4QLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1085623:GNIT RS14025
gene id: 1085623:GNIT_RS14025
uniprot id: G4QMW9
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS06360
gene id: 1085623:GNIT_RS06360
uniprot id: G4QGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS00065
gene id: 1085623:GNIT_RS00065
uniprot id: G4QEE6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1085623:GNIT RS09420
gene id: 1085623:GNIT_RS09420
uniprot id: G4QKM2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1085623:GNIT RS10030
gene id: 1085623:GNIT_RS10030
uniprot id: G4QH26
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1085623:GNIT RS13550
gene id: 1085623:GNIT_RS13550
uniprot id: G4QMJ5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1085623:GNIT RS00335
gene id: 1085623:GNIT_RS00335
uniprot id: G4QEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1085623:GNIT RS14665
gene id: 1085623:GNIT_RS14665
uniprot id: G4QIN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1085623:GNIT RS05500
gene id: 1085623:GNIT_RS05500
uniprot id: G4QK83
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09335
gene id: 1085623:GNIT_RS09335
uniprot id: G4QKK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1085623:GNIT RS16400
gene id: 1085623:GNIT_RS16400
uniprot id: G4QND9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1085623:GNIT RS00035
gene id: 1085623:GNIT_RS00035
uniprot id: G4QEE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1085623:GNIT RS09125
gene id: 1085623:GNIT_RS09125
uniprot id: G4QKG0
names: Similarity
messages: Belongs to the UPF0178 family.

1085623:GNIT RS02290
gene id: 1085623:GNIT_RS02290
uniprot id: G4QFL4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS15735
gene id: 1085623:GNIT_RS15735
uniprot id: G4QMZ7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1085623:GNIT RS05875
gene id: 1085623:GNIT_RS05875
uniprot id: G4QKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1085623:GNIT RS17250
gene id: 1085623:GNIT_RS17250
uniprot id: G4QP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1085623:GNIT RS14645
gene id: 1085623:GNIT_RS14645
uniprot id: G4QIM7
names: Similarity
messages: Belongs to the peptidase S8 family.

1085623:GNIT RS10185
gene id: 1085623:GNIT_RS10185
uniprot id: G4QH60
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1085623:GNIT RS04425
gene id: 1085623:GNIT_RS04425
uniprot id: G4QFX5
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1085623:GNIT RS01770
gene id: 1085623:GNIT_RS01770
uniprot id: G4QJC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1085623:GNIT RS10110
gene id: 1085623:GNIT_RS10110
uniprot id: G4QH43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1085623:GNIT RS02640
gene id: 1085623:GNIT_RS02640
uniprot id: G4QJP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS01955
gene id: 1085623:GNIT_RS01955
uniprot id: G4QJG0
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1085623:GNIT RS11490
gene id: 1085623:GNIT_RS11490
uniprot id: G4QHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1085623:GNIT RS08565
gene id: 1085623:GNIT_RS08565
uniprot id: G4QGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1085623:GNIT RS06315
gene id: 1085623:GNIT_RS06315
uniprot id: G4QGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS05845
gene id: 1085623:GNIT_RS05845
uniprot id: G4QKW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS00645
gene id: 1085623:GNIT_RS00645
uniprot id: G4QIV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS05860
gene id: 1085623:GNIT_RS05860
uniprot id: G4QKX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1085623:GNIT RS13500
gene id: 1085623:GNIT_RS13500
uniprot id: G4QMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS02970
gene id: 1085623:GNIT_RS02970
uniprot id: G4QEL2
names: Similarity
messages: Belongs to the Dps family.

1085623:GNIT RS14670
gene id: 1085623:GNIT_RS14670
uniprot id: G4QIN3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1085623:GNIT RS16950
gene id: 1085623:GNIT_RS16950
uniprot id: G4QNW6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS00640
gene id: 1085623:GNIT_RS00640
uniprot id: G4QIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1085623:GNIT RS07745
gene id: 1085623:GNIT_RS07745
uniprot id: G4QHB5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1085623:GNIT RS01050
gene id: 1085623:GNIT_RS01050
uniprot id: G4QF31
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1085623:GNIT RS17345
gene id: 1085623:GNIT_RS17345
uniprot id: G4QNF6
names: Similarity
messages: Belongs to the pirin family.

1085623:GNIT RS14185
gene id: 1085623:GNIT_RS14185
uniprot id: G4QDQ6
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1085623:GNIT RS03080
gene id: 1085623:GNIT_RS03080
uniprot id: G4QEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1085623:GNIT RS15090
gene id: 1085623:GNIT_RS15090
uniprot id: G4QE03
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1085623:GNIT RS04775
gene id: 1085623:GNIT_RS04775
uniprot id: G4QK21
names: Similarity
messages: Belongs to the PspA/IM30 family.

1085623:GNIT RS04930
gene id: 1085623:GNIT_RS04930
uniprot id: G4QK54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1085623:GNIT RS08525
gene id: 1085623:GNIT_RS08525
uniprot id: G4QGV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13395
gene id: 1085623:GNIT_RS13395
uniprot id: G4QMG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS05280
gene id: 1085623:GNIT_RS05280
uniprot id: G4QG76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1085623:GNIT RS02860
gene id: 1085623:GNIT_RS02860
uniprot id: G4QEJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1085623:GNIT RS10785
gene id: 1085623:GNIT_RS10785
uniprot id: G4QKR2
names: Similarity
messages: Belongs to the glyoxalase I family.

1085623:GNIT RS05470
gene id: 1085623:GNIT_RS05470
uniprot id: G4QK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS15730
gene id: 1085623:GNIT_RS15730
uniprot id: G4QMZ6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1085623:GNIT RS09230
gene id: 1085623:GNIT_RS09230
uniprot id: G4QKI4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS07580
gene id: 1085623:GNIT_RS07580
uniprot id: G4QH83
names: Similarity
messages: Belongs to the HsdR family.

1085623:GNIT RS13215
gene id: 1085623:GNIT_RS13215
uniprot id: G4QIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1085623:GNIT RS11215
gene id: 1085623:GNIT_RS11215
uniprot id: G4QLW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1085623:GNIT RS10020
gene id: 1085623:GNIT_RS10020
uniprot id: G4QH24
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1085623:GNIT RS07685
gene id: 1085623:GNIT_RS07685
uniprot id: G4QHA3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1085623:GNIT RS08990
gene id: 1085623:GNIT_RS08990
uniprot id: G4QHL3
names: Similarity
messages: Belongs to the peptidase S41A family.

1085623:GNIT RS10140
gene id: 1085623:GNIT_RS10140
uniprot id: G4QH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

1085623:GNIT RS03120
gene id: 1085623:GNIT_RS03120
uniprot id: G4QFM0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1085623:GNIT RS16195
gene id: 1085623:GNIT_RS16195
uniprot id: G4QN94
names: Similarity
messages: Belongs to the peptidase M24B family.

1085623:GNIT RS10530
gene id: 1085623:GNIT_RS10530
uniprot id: G4QHT7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1085623:GNIT RS09765
gene id: 1085623:GNIT_RS09765
uniprot id: G4QLQ5
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS05095
gene id: 1085623:GNIT_RS05095
uniprot id: G4QG38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1085623:GNIT RS17135
gene id: 1085623:GNIT_RS17135
uniprot id: G4QP03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1085623:GNIT RS03285
gene id: 1085623:GNIT_RS03285
uniprot id: G4QFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS04720
gene id: 1085623:GNIT_RS04720
uniprot id: G4QK10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS11195
gene id: 1085623:GNIT_RS11195
uniprot id: G4QLV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1085623:GNIT RS02250
gene id: 1085623:GNIT_RS02250
uniprot id: G4QFK6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1085623:GNIT RS01400
gene id: 1085623:GNIT_RS01400
uniprot id: G4QFA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1085623:GNIT RS11170
gene id: 1085623:GNIT_RS11170
uniprot id: G4QLV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1085623:GNIT RS16455
gene id: 1085623:GNIT_RS16455
uniprot id: G4QNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1085623:GNIT RS10710
gene id: 1085623:GNIT_RS10710
uniprot id: G4QKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1085623:GNIT RS01015
gene id: 1085623:GNIT_RS01015
uniprot id: G4QF24
names: Similarity
messages: Belongs to the RutC family.

1085623:GNIT RS01045
gene id: 1085623:GNIT_RS01045
uniprot id: G4QF30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1085623:GNIT RS14885
gene id: 1085623:GNIT_RS14885
uniprot id: G4QJ90
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1085623:GNIT RS06460
gene id: 1085623:GNIT_RS06460
uniprot id: G4QGF9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1085623:GNIT RS08995
gene id: 1085623:GNIT_RS08995
uniprot id: G4QHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

1085623:GNIT RS12240
gene id: 1085623:GNIT_RS12240
uniprot id: G4QI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1085623:GNIT RS01865
gene id: 1085623:GNIT_RS01865
uniprot id: G4QJE0
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS05350
gene id: 1085623:GNIT_RS05350
uniprot id: G4QG90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1085623:GNIT RS05240
gene id: 1085623:GNIT_RS05240
uniprot id: G4QG68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1085623:GNIT RS00825
gene id: 1085623:GNIT_RS00825
uniprot id: G4QIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1085623:GNIT RS03975
gene id: 1085623:GNIT_RS03975
uniprot id: G4QJT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS07825
gene id: 1085623:GNIT_RS07825
uniprot id: G4QHD3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1085623:GNIT RS16010
gene id: 1085623:GNIT_RS16010
uniprot id: G4QN55
names: Similarity
messages: Belongs to the peptidase S8 family.

1085623:GNIT RS02460
gene id: 1085623:GNIT_RS02460
uniprot id: G4QJL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1085623:GNIT RS10405
gene id: 1085623:GNIT_RS10405
uniprot id: G4QHR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS04200
gene id: 1085623:GNIT_RS04200
uniprot id: G4QJX9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1085623:GNIT RS13770
gene id: 1085623:GNIT_RS13770
uniprot id: G4QMR1
names: Subcellular Location Annotation
messages: Cell outer membrane

1085623:GNIT RS13795
gene id: 1085623:GNIT_RS13795
uniprot id: G4QMR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1085623:GNIT RS12770
gene id: 1085623:GNIT_RS12770
uniprot id: G4QMD2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1085623:GNIT RS11910
gene id: 1085623:GNIT_RS11910
uniprot id: G4QM29
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1085623:GNIT RS05420
gene id: 1085623:GNIT_RS05420
uniprot id: G4QK69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS09750
gene id: 1085623:GNIT_RS09750
uniprot id: G4QLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1085623:GNIT RS09695
gene id: 1085623:GNIT_RS09695
uniprot id: G4QLP0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1085623:GNIT RS02215
gene id: 1085623:GNIT_RS02215
uniprot id: G4QFJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS02960
gene id: 1085623:GNIT_RS02960
uniprot id: G4QEL0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1085623:GNIT RS13310
gene id: 1085623:GNIT_RS13310
uniprot id: G4QII3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1085623:GNIT RS03545
gene id: 1085623:GNIT_RS03545
uniprot id: G4QJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1085623:GNIT RS07130
gene id: 1085623:GNIT_RS07130
uniprot id: G4QGI0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1085623:GNIT RS02880
gene id: 1085623:GNIT_RS02880
uniprot id: G4QEJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS01775
gene id: 1085623:GNIT_RS01775
uniprot id: G4QJC1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1085623:GNIT RS11420
gene id: 1085623:GNIT_RS11420
uniprot id: G4QHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1085623:GNIT RS15210
gene id: 1085623:GNIT_RS15210
uniprot id: G4QE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1085623:GNIT RS14895
gene id: 1085623:GNIT_RS14895
uniprot id: G4QJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1085623:GNIT RS10890
gene id: 1085623:GNIT_RS10890
uniprot id: G4QKT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS14240
gene id: 1085623:GNIT_RS14240
uniprot id: G4QDS0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1085623:GNIT RS00405
gene id: 1085623:GNIT_RS00405
uniprot id: G4QEX7
names: Similarity
messages: Belongs to the nitroreductase family.

1085623:GNIT RS09030
gene id: 1085623:GNIT_RS09030
uniprot id: G4QHM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1085623:GNIT RS13555
gene id: 1085623:GNIT_RS13555
uniprot id: G4QMJ6
names: Similarity
messages: Belongs to the TPP enzyme family.

1085623:GNIT RS13575
gene id: 1085623:GNIT_RS13575
uniprot id: G4QMK2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1085623:GNIT RS12280
gene id: 1085623:GNIT_RS12280
uniprot id: G4QI66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS12290
gene id: 1085623:GNIT_RS12290
uniprot id: G4QI68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS08955
gene id: 1085623:GNIT_RS08955
uniprot id: G4QHK5
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS07500
gene id: 1085623:GNIT_RS07500
uniprot id: G4QGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1085623:GNIT RS10225
gene id: 1085623:GNIT_RS10225
uniprot id: G4QHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1085623:GNIT RS15115
gene id: 1085623:GNIT_RS15115
uniprot id: G4QE08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1085623:GNIT RS13535
gene id: 1085623:GNIT_RS13535
uniprot id: G4QMJ2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1085623:GNIT RS11725
gene id: 1085623:GNIT_RS11725
uniprot id: G4QI27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1085623:GNIT RS03695
gene id: 1085623:GNIT_RS03695
uniprot id: G4QJ50
names: Similarity
messages: Belongs to the peptidase M17 family.

1085623:GNIT RS13335
gene id: 1085623:GNIT_RS13335
uniprot id: G4QII8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1085623:GNIT RS15715
gene id: 1085623:GNIT_RS15715
uniprot id: G4QMZ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1085623:GNIT RS13465
gene id: 1085623:GNIT_RS13465
uniprot id: G4QMH7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1085623:GNIT RS04955
gene id: 1085623:GNIT_RS04955
uniprot id: G4QK59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS14740
gene id: 1085623:GNIT_RS14740
uniprot id: G4QIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1085623:GNIT RS03625
gene id: 1085623:GNIT_RS03625
uniprot id: G4QJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1085623:GNIT RS09120
gene id: 1085623:GNIT_RS09120
uniprot id: G4QKF9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1085623:GNIT RS18020
gene id: 1085623:GNIT_RS18020
uniprot id: G4QN43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1085623:GNIT RS02125
gene id: 1085623:GNIT_RS02125
uniprot id: G4QFH8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1085623:GNIT RS10010
gene id: 1085623:GNIT_RS10010
uniprot id: G4QH22
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1085623:GNIT RS10080
gene id: 1085623:GNIT_RS10080
uniprot id: G4QH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1085623:GNIT RS00370
gene id: 1085623:GNIT_RS00370
uniprot id: G4QEX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1085623:GNIT RS11505
gene id: 1085623:GNIT_RS11505
uniprot id: G4QHX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1085623:GNIT RS04010
gene id: 1085623:GNIT_RS04010
uniprot id: G4QJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1085623:GNIT RS11870
gene id: 1085623:GNIT_RS11870
uniprot id: G4QM21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1085623:GNIT RS17245
gene id: 1085623:GNIT_RS17245
uniprot id: G4QP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1085623:GNIT RS09755
gene id: 1085623:GNIT_RS09755
uniprot id: G4QLQ3
names: Similarity
messages: Belongs to the UPF0434 family.

1085623:GNIT RS11445
gene id: 1085623:GNIT_RS11445
uniprot id: G4QHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1085623:GNIT RS03540
gene id: 1085623:GNIT_RS03540
uniprot id: G4QJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1085623:GNIT RS13710
gene id: 1085623:GNIT_RS13710
uniprot id: G4QMN0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1085623:GNIT RS08235
gene id: 1085623:GNIT_RS08235
uniprot id: G4QLH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1085623:GNIT RS08750
gene id: 1085623:GNIT_RS08750
uniprot id: G4QHG1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1085623:GNIT RS08900
gene id: 1085623:GNIT_RS08900
uniprot id: G4QHJ4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1085623:GNIT RS09670
gene id: 1085623:GNIT_RS09670
uniprot id: G4QLN5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1085623:GNIT RS09080
gene id: 1085623:GNIT_RS09080
uniprot id: G4QKF1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1085623:GNIT RS05040
gene id: 1085623:GNIT_RS05040
uniprot id: G4QG27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1085623:GNIT RS15160
gene id: 1085623:GNIT_RS15160
uniprot id: G4QE16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1085623:GNIT RS00340
gene id: 1085623:GNIT_RS00340
uniprot id: G4QEW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1085623:GNIT RS08470
gene id: 1085623:GNIT_RS08470
uniprot id: G4QGU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1085623:GNIT RS01945
gene id: 1085623:GNIT_RS01945
uniprot id: G4QJF8
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS04885
gene id: 1085623:GNIT_RS04885
uniprot id: G4QK43
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1085623:GNIT RS13910
gene id: 1085623:GNIT_RS13910
uniprot id: G4QMU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1085623:GNIT RS03040
gene id: 1085623:GNIT_RS03040
uniprot id: G4QEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1085623:GNIT RS15425
gene id: 1085623:GNIT_RS15425
uniprot id: G4QE72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS00930
gene id: 1085623:GNIT_RS00930
uniprot id: G4QF04
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1085623:GNIT RS08545
gene id: 1085623:GNIT_RS08545
uniprot id: G4QGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1085623:GNIT RS06970
gene id: 1085623:GNIT_RS06970
uniprot id: G4QEP7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1085623:GNIT RS04800
gene id: 1085623:GNIT_RS04800
uniprot id: G4QK26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1085623:GNIT RS10650
gene id: 1085623:GNIT_RS10650
uniprot id: G4QKN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS02175
gene id: 1085623:GNIT_RS02175
uniprot id: G4QFI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1085623:GNIT RS03800
gene id: 1085623:GNIT_RS03800
uniprot id: G4QJ75
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS02995
gene id: 1085623:GNIT_RS02995
uniprot id: G4QEL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1085623:GNIT RS11255
gene id: 1085623:GNIT_RS11255
uniprot id: G4QLW9
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS04065
gene id: 1085623:GNIT_RS04065
uniprot id: G4QJV1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS17515
gene id: 1085623:GNIT_RS17515
uniprot id: G4QNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1085623:GNIT RS01900
gene id: 1085623:GNIT_RS01900
uniprot id: G4QJE9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1085623:GNIT RS03925
gene id: 1085623:GNIT_RS03925
uniprot id: G4QJS8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1085623:GNIT RS16550
gene id: 1085623:GNIT_RS16550
uniprot id: G4QNN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS10525
gene id: 1085623:GNIT_RS10525
uniprot id: G4QHT6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1085623:GNIT RS01985
gene id: 1085623:GNIT_RS01985
uniprot id: G4QJG8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1085623:GNIT RS15740
gene id: 1085623:GNIT_RS15740
uniprot id: G4QMZ8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1085623:GNIT RS06415
gene id: 1085623:GNIT_RS06415
uniprot id: G4QGF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1085623:GNIT RS09850
gene id: 1085623:GNIT_RS09850
uniprot id: G4QGY9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1085623:GNIT RS02590
gene id: 1085623:GNIT_RS02590
uniprot id: G4QJN9
names: Similarity
messages: Belongs to the glutamate synthase family.

1085623:GNIT RS01425
gene id: 1085623:GNIT_RS01425
uniprot id: G4QFA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS02395
gene id: 1085623:GNIT_RS02395
uniprot id: G4QJK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1085623:GNIT RS02630
gene id: 1085623:GNIT_RS02630
uniprot id: G4QJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS10875
gene id: 1085623:GNIT_RS10875
uniprot id: G4QKT1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS00235
gene id: 1085623:GNIT_RS00235
uniprot id: G4QEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1085623:GNIT RS13880
gene id: 1085623:GNIT_RS13880
uniprot id: G4QMT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1085623:GNIT RS02565
gene id: 1085623:GNIT_RS02565
uniprot id: G4QJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1085623:GNIT RS00365
gene id: 1085623:GNIT_RS00365
uniprot id: G4QEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS10695
gene id: 1085623:GNIT_RS10695
uniprot id: G4QKP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1085623:GNIT RS11665
gene id: 1085623:GNIT_RS11665
uniprot id: G4QI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1085623:GNIT RS01915
gene id: 1085623:GNIT_RS01915
uniprot id: G4QJF2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS13195
gene id: 1085623:GNIT_RS13195
uniprot id: G4QIF9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1085623:GNIT RS15050
gene id: 1085623:GNIT_RS15050
uniprot id: G4QDZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1085623:GNIT RS09745
gene id: 1085623:GNIT_RS09745
uniprot id: G4QLQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1085623:GNIT RS09820
gene id: 1085623:GNIT_RS09820
uniprot id: G4QLR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS11625
gene id: 1085623:GNIT_RS11625
uniprot id: G4QI06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1085623:GNIT RS05675
gene id: 1085623:GNIT_RS05675
uniprot id: G4QKC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1085623:GNIT RS08210
gene id: 1085623:GNIT_RS08210
uniprot id: G4QLH3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1085623:GNIT RS09320
gene id: 1085623:GNIT_RS09320
uniprot id: G4QKK3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1085623:GNIT RS05270
gene id: 1085623:GNIT_RS05270
uniprot id: G4QG74
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1085623:GNIT RS08460
gene id: 1085623:GNIT_RS08460
uniprot id: G4QGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS08985
gene id: 1085623:GNIT_RS08985
uniprot id: G4QHL2
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS01190
gene id: 1085623:GNIT_RS01190
uniprot id: G4QF59
names: Similarity
messages: Belongs to the thioredoxin family.

1085623:GNIT RS09780
gene id: 1085623:GNIT_RS09780
uniprot id: G4QLQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS10175
gene id: 1085623:GNIT_RS10175
uniprot id: G4QH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1085623:GNIT RS14840
gene id: 1085623:GNIT_RS14840
uniprot id: G4QIR9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1085623:GNIT RS14320
gene id: 1085623:GNIT_RS14320
uniprot id: G4QDT6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1085623:GNIT RS08230
gene id: 1085623:GNIT_RS08230
uniprot id: G4QLH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1085623:GNIT RS06200
gene id: 1085623:GNIT_RS06200
uniprot id: G4QGA6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1085623:GNIT RS09790
gene id: 1085623:GNIT_RS09790
uniprot id: G4QLR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1085623:GNIT RS14475
gene id: 1085623:GNIT_RS14475
uniprot id: G4QDW7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1085623:GNIT RS10330
gene id: 1085623:GNIT_RS10330
uniprot id: G4QHP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1085623:GNIT RS06080
gene id: 1085623:GNIT_RS06080
uniprot id: G4QL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS10100
gene id: 1085623:GNIT_RS10100
uniprot id: G4QH41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1085623:GNIT RS09150
gene id: 1085623:GNIT_RS09150
uniprot id: G4QKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS12305
gene id: 1085623:GNIT_RS12305
uniprot id: G4QI71
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1085623:GNIT RS05005
gene id: 1085623:GNIT_RS05005
uniprot id: G4QK64
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1085623:GNIT RS04685
gene id: 1085623:GNIT_RS04685
uniprot id: G4QK01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1085623:GNIT RS06140
gene id: 1085623:GNIT_RS06140
uniprot id: G4QL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1085623:GNIT RS01410
gene id: 1085623:GNIT_RS01410
uniprot id: G4QFA6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1085623:GNIT RS01095
gene id: 1085623:GNIT_RS01095
uniprot id: G4QF40
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1085623:GNIT RS06800
gene id: 1085623:GNIT_RS06800
uniprot id: G4QL80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1085623:GNIT RS17565
gene id: 1085623:GNIT_RS17565
uniprot id: G4QNK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS02410
gene id: 1085623:GNIT_RS02410
uniprot id: G4QJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1085623:GNIT RS07960
gene id: 1085623:GNIT_RS07960
uniprot id: G4QLC4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1085623:GNIT RS06550
gene id: 1085623:GNIT_RS06550
uniprot id: G4QGH7
names: Similarity
messages: Belongs to the SufE family.

1085623:GNIT RS02265
gene id: 1085623:GNIT_RS02265
uniprot id: G4QFK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1085623:GNIT RS12945
gene id: 1085623:GNIT_RS12945
uniprot id: G4QMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1085623:GNIT RS01330
gene id: 1085623:GNIT_RS01330
uniprot id: G4QF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS05285
gene id: 1085623:GNIT_RS05285
uniprot id: G4QG77
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1085623:GNIT RS01795
gene id: 1085623:GNIT_RS01795
uniprot id: G4QJC5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1085623:GNIT RS10160
gene id: 1085623:GNIT_RS10160
uniprot id: G4QH54
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1085623:GNIT RS04120
gene id: 1085623:GNIT_RS04120
uniprot id: G4QJW2
names: Similarity
messages: Belongs to the AHA1 family.

1085623:GNIT RS10625
gene id: 1085623:GNIT_RS10625
uniprot id: G4QKN1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS16405
gene id: 1085623:GNIT_RS16405
uniprot id: G4QNE0
names: Similarity
messages: Belongs to the HSP15 family.

1085623:GNIT RS05805
gene id: 1085623:GNIT_RS05805
uniprot id: G4QKW0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1085623:GNIT RS09785
gene id: 1085623:GNIT_RS09785
uniprot id: G4QLQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1085623:GNIT RS09720
gene id: 1085623:GNIT_RS09720
uniprot id: G4QLP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS05020
gene id: 1085623:GNIT_RS05020
uniprot id: G4QG23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1085623:GNIT RS01505
gene id: 1085623:GNIT_RS01505
uniprot id: G4QFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1085623:GNIT RS05260
gene id: 1085623:GNIT_RS05260
uniprot id: G4QG72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1085623:GNIT RS11485
gene id: 1085623:GNIT_RS11485
uniprot id: G4QHX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1085623:GNIT RS00095
gene id: 1085623:GNIT_RS00095
uniprot id: G4QEF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1085623:GNIT RS13330
gene id: 1085623:GNIT_RS13330
uniprot id: G4QII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1085623:GNIT RS16445
gene id: 1085623:GNIT_RS16445
uniprot id: G4QNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS01680
gene id: 1085623:GNIT_RS01680
uniprot id: G4QJA3
names: Similarity
messages: Belongs to the peptidase U62 family.

1085623:GNIT RS08685
gene id: 1085623:GNIT_RS08685
uniprot id: G4QHE8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1085623:GNIT RS12750
gene id: 1085623:GNIT_RS12750
uniprot id: G4QMC8
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

1085623:GNIT RS04255
gene id: 1085623:GNIT_RS04255
uniprot id: G4QFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1085623:GNIT RS12845
gene id: 1085623:GNIT_RS12845
uniprot id: G4QME7
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1085623:GNIT RS10415
gene id: 1085623:GNIT_RS10415
uniprot id: G4QHR2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1085623:GNIT RS17530
gene id: 1085623:GNIT_RS17530
uniprot id: G4QNJ5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1085623:GNIT RS13780
gene id: 1085623:GNIT_RS13780
uniprot id: G4QMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1085623:GNIT RS06645
gene id: 1085623:GNIT_RS06645
uniprot id: G4QL46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1085623:GNIT RS15970
gene id: 1085623:GNIT_RS15970
uniprot id: G4QN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS09935
gene id: 1085623:GNIT_RS09935
uniprot id: G4QH07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1085623:GNIT RS05215
gene id: 1085623:GNIT_RS05215
uniprot id: G4QG63
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1085623:GNIT RS14620
gene id: 1085623:GNIT_RS14620
uniprot id: G4QIM2
names: Similarity
messages: Belongs to the ArsC family.

1085623:GNIT RS08485
gene id: 1085623:GNIT_RS08485
uniprot id: G4QGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1085623:GNIT RS15620
gene id: 1085623:GNIT_RS15620
uniprot id: G4QEB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1085623:GNIT RS07680
gene id: 1085623:GNIT_RS07680
uniprot id: G4QHA2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1085623:GNIT RS02420
gene id: 1085623:GNIT_RS02420
uniprot id: G4QJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1085623:GNIT RS01010
gene id: 1085623:GNIT_RS01010
uniprot id: G4QF23
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1085623:GNIT RS09840
gene id: 1085623:GNIT_RS09840
uniprot id: G4QGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1085623:GNIT RS16505
gene id: 1085623:GNIT_RS16505
uniprot id: G4QNM1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09085
gene id: 1085623:GNIT_RS09085
uniprot id: G4QKF2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1085623:GNIT RS03375
gene id: 1085623:GNIT_RS03375
uniprot id: G4QFR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1085623:GNIT RS17010
gene id: 1085623:GNIT_RS17010
uniprot id: G4QNX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS07515
gene id: 1085623:GNIT_RS07515
uniprot id: G4QH67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1085623:GNIT RS09580
gene id: 1085623:GNIT_RS09580
uniprot id: G4QLL5
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13160
gene id: 1085623:GNIT_RS13160
uniprot id: G4QIF2
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1085623:GNIT RS12925
gene id: 1085623:GNIT_RS12925
uniprot id: G4QMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1085623:GNIT RS12055
gene id: 1085623:GNIT_RS12055
uniprot id: G4QM61
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1085623:GNIT RS01755
gene id: 1085623:GNIT_RS01755
uniprot id: G4QJB7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1085623:GNIT RS16100
gene id: 1085623:GNIT_RS16100
uniprot id: G4QN75
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09645
gene id: 1085623:GNIT_RS09645
uniprot id: G4QLN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1085623:GNIT RS07080
gene id: 1085623:GNIT_RS07080
uniprot id: G4QER8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1085623:GNIT RS09940
gene id: 1085623:GNIT_RS09940
uniprot id: G4QH08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1085623:GNIT RS05540
gene id: 1085623:GNIT_RS05540
uniprot id: G4QK92
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1085623:GNIT RS09680
gene id: 1085623:GNIT_RS09680
uniprot id: G4QLN7
names: Similarity
messages: Belongs to the citrate synthase family.

1085623:GNIT RS12830
gene id: 1085623:GNIT_RS12830
uniprot id: G4QME4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS13375
gene id: 1085623:GNIT_RS13375
uniprot id: G4QMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1085623:GNIT RS05575
gene id: 1085623:GNIT_RS05575
uniprot id: G4QKA0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1085623:GNIT RS13265
gene id: 1085623:GNIT_RS13265
uniprot id: G4QIH4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS09260
gene id: 1085623:GNIT_RS09260
uniprot id: G4QKJ1
names: Similarity
messages: Belongs to the CvfB family.

1085623:GNIT RS08690
gene id: 1085623:GNIT_RS08690
uniprot id: G4QHE9
names: Similarity
messages: Belongs to the universal stress protein A family.

1085623:GNIT RS05635
gene id: 1085623:GNIT_RS05635
uniprot id: G4QKB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1085623:GNIT RS15260
gene id: 1085623:GNIT_RS15260
uniprot id: G4QE36
names: Similarity
messages: Belongs to the MipA/OmpV family.

1085623:GNIT RS14975
gene id: 1085623:GNIT_RS14975
uniprot id: G4QDX8
names: Similarity
messages: Belongs to the PrpF family.

1085623:GNIT RS04875
gene id: 1085623:GNIT_RS04875
uniprot id: G4QK41
names: Similarity
messages: Belongs to the YfgM family.

1085623:GNIT RS01005
gene id: 1085623:GNIT_RS01005
uniprot id: G4QF22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1085623:GNIT RS03675
gene id: 1085623:GNIT_RS03675
uniprot id: G4QJ46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1085623:GNIT RS03100
gene id: 1085623:GNIT_RS03100
uniprot id: G4QEN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1085623:GNIT RS03240
gene id: 1085623:GNIT_RS03240
uniprot id: G4QFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1085623:GNIT RS15415
gene id: 1085623:GNIT_RS15415
uniprot id: G4QE70
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1085623:GNIT RS13035
gene id: 1085623:GNIT_RS13035
uniprot id: G4QIC6
names: Similarity
messages: Belongs to the GSP E family.

1085623:GNIT RS13430
gene id: 1085623:GNIT_RS13430
uniprot id: G4QMG9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1085623:GNIT RS14040
gene id: 1085623:GNIT_RS14040
uniprot id: G4QMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085623:GNIT RS17175
gene id: 1085623:GNIT_RS17175
uniprot id: G4QP13
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1085623:GNIT RS11265
gene id: 1085623:GNIT_RS11265
uniprot id: G4QLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1085623:GNIT RS16350
gene id: 1085623:GNIT_RS16350
uniprot id: G4QNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1085623:GNIT RS04635
gene id: 1085623:GNIT_RS04635
uniprot id: G4QJZ1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13190
gene id: 1085623:GNIT_RS13190
uniprot id: G4QIF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS10355
gene id: 1085623:GNIT_RS10355
uniprot id: G4QHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1085623:GNIT RS16670
gene id: 1085623:GNIT_RS16670
uniprot id: G4QNQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS02705
gene id: 1085623:GNIT_RS02705
uniprot id: G4QJR3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1085623:GNIT RS11905
gene id: 1085623:GNIT_RS11905
uniprot id: G4QM28
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1085623:GNIT RS16510
gene id: 1085623:GNIT_RS16510
uniprot id: G4QNM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1085623:GNIT RS08155
gene id: 1085623:GNIT_RS08155
uniprot id: G4QLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1085623:GNIT RS09575
gene id: 1085623:GNIT_RS09575
uniprot id: G4QLL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS10655
gene id: 1085623:GNIT_RS10655
uniprot id: G4QKN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1085623:GNIT RS05890
gene id: 1085623:GNIT_RS05890
uniprot id: G4QKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1085623:GNIT RS03500
gene id: 1085623:GNIT_RS03500
uniprot id: G4QFU0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1085623:GNIT RS09325
gene id: 1085623:GNIT_RS09325
uniprot id: G4QKK4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1085623:GNIT RS00120
gene id: 1085623:GNIT_RS00120
uniprot id: G4QEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1085623:GNIT RS17195
gene id: 1085623:GNIT_RS17195
uniprot id: G4QP18
names: Function
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1085623:GNIT RS06850
gene id: 1085623:GNIT_RS06850
uniprot id: G4QL90
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1085623:GNIT RS11250
gene id: 1085623:GNIT_RS11250
uniprot id: G4QLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS05550
gene id: 1085623:GNIT_RS05550
uniprot id: G4QK94
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1085623:GNIT RS02050
gene id: 1085623:GNIT_RS02050
uniprot id: G4QJI3
names: Similarity
messages: Belongs to the elongation factor P family.

1085623:GNIT RS13045
gene id: 1085623:GNIT_RS13045
uniprot id: G4QIC8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1085623:GNIT RS08345
gene id: 1085623:GNIT_RS08345
uniprot id: G4QGS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS15490
gene id: 1085623:GNIT_RS15490
uniprot id: G4QE85
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS02220
gene id: 1085623:GNIT_RS02220
uniprot id: G4QFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1085623:GNIT RS02260
gene id: 1085623:GNIT_RS02260
uniprot id: G4QFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1085623:GNIT RS04795
gene id: 1085623:GNIT_RS04795
uniprot id: G4QK25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1085623:GNIT RS16135
gene id: 1085623:GNIT_RS16135
uniprot id: G4QN82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS13915
gene id: 1085623:GNIT_RS13915
uniprot id: G4QMU3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1085623:GNIT RS10115
gene id: 1085623:GNIT_RS10115
uniprot id: G4QH44
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1085623:GNIT RS16870
gene id: 1085623:GNIT_RS16870
uniprot id: G4QNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1085623:GNIT RS14390
gene id: 1085623:GNIT_RS14390
uniprot id: G4QDV1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1085623:GNIT RS07760
gene id: 1085623:GNIT_RS07760
uniprot id: G4QHB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS11775
gene id: 1085623:GNIT_RS11775
uniprot id: G4QM00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS09535
gene id: 1085623:GNIT_RS09535
uniprot id: G4QLK6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1085623:GNIT RS01415
gene id: 1085623:GNIT_RS01415
uniprot id: G4QFA7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1085623:GNIT RS09660
gene id: 1085623:GNIT_RS09660
uniprot id: G4QLN3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1085623:GNIT RS08165
gene id: 1085623:GNIT_RS08165
uniprot id: G4QLG4
names: Similarity
messages: Belongs to the intimin/invasin family.

1085623:GNIT RS05735
gene id: 1085623:GNIT_RS05735
uniprot id: G4QKD7
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1085623:GNIT RS00260
gene id: 1085623:GNIT_RS00260
uniprot id: G4QEU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1085623:GNIT RS14490
gene id: 1085623:GNIT_RS14490
uniprot id: G4QDW9
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13785
gene id: 1085623:GNIT_RS13785
uniprot id: G4QMR5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1085623:GNIT RS01785
gene id: 1085623:GNIT_RS01785
uniprot id: G4QJC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1085623:GNIT RS17685
gene id: 1085623:GNIT_RS17685
uniprot id: G4QHC7
names: Subcellular Location Annotation
messages: Cell inner membrane

1085623:GNIT RS01465
gene id: 1085623:GNIT_RS01465
uniprot id: G4QFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS10485
gene id: 1085623:GNIT_RS10485
uniprot id: G4QHS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS02510
gene id: 1085623:GNIT_RS02510
uniprot id: G4QJM3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1085623:GNIT RS08055
gene id: 1085623:GNIT_RS08055
uniprot id: G4QLE4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1085623:GNIT RS10490
gene id: 1085623:GNIT_RS10490
uniprot id: G4QHS9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1085623:GNIT RS11240
gene id: 1085623:GNIT_RS11240
uniprot id: G4QLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1085623:GNIT RS12990
gene id: 1085623:GNIT_RS12990
uniprot id: G4QIB6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1085623:GNIT RS13480
gene id: 1085623:GNIT_RS13480
uniprot id: G4QMI0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1085623:GNIT RS11885
gene id: 1085623:GNIT_RS11885
uniprot id: G4QM24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1085623:GNIT RS12585
gene id: 1085623:GNIT_RS12585
uniprot id: G4QM94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS03215
gene id: 1085623:GNIT_RS03215
uniprot id: G4QFN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS10830
gene id: 1085623:GNIT_RS10830
uniprot id: G4QKS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1085623:GNIT RS14535
gene id: 1085623:GNIT_RS14535
uniprot id: G4QIK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1085623:GNIT RS08250
gene id: 1085623:GNIT_RS08250
uniprot id: G4QLI1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1085623:GNIT RS14945
gene id: 1085623:GNIT_RS14945
uniprot id: G4QDX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS04830
gene id: 1085623:GNIT_RS04830
uniprot id: G4QK32
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1085623:GNIT RS09185
gene id: 1085623:GNIT_RS09185
uniprot id: G4QKH5
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1085623:GNIT RS05025
gene id: 1085623:GNIT_RS05025
uniprot id: G4QG24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS01470
gene id: 1085623:GNIT_RS01470
uniprot id: G4QFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1085623:GNIT RS17080
gene id: 1085623:GNIT_RS17080
uniprot id: G4QNZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1085623:GNIT RS16820
gene id: 1085623:GNIT_RS16820
uniprot id: G4QNT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1085623:GNIT RS07950
gene id: 1085623:GNIT_RS07950
uniprot id: G4QLC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1085623:GNIT RS01075
gene id: 1085623:GNIT_RS01075
uniprot id: G4QF36
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

1085623:GNIT RS03315
gene id: 1085623:GNIT_RS03315
uniprot id: G4QFQ2
names: Similarity
messages: Belongs to the aspartokinase family.

1085623:GNIT RS15795
gene id: 1085623:GNIT_RS15795
uniprot id: G4QN09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS10580
gene id: 1085623:GNIT_RS10580
uniprot id: G4QHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1085623:GNIT RS08680
gene id: 1085623:GNIT_RS08680
uniprot id: G4QHE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS05855
gene id: 1085623:GNIT_RS05855
uniprot id: G4QKX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1085623:GNIT RS10605
gene id: 1085623:GNIT_RS10605
uniprot id: G4QKM7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1085623:GNIT RS01645
gene id: 1085623:GNIT_RS01645
uniprot id: G4QFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1085623:GNIT RS06785
gene id: 1085623:GNIT_RS06785
uniprot id: G4QL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1085623:GNIT RS13855
gene id: 1085623:GNIT_RS13855
uniprot id: G4QMT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1085623:GNIT RS06910
gene id: 1085623:GNIT_RS06910
uniprot id: G4QLA4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1085623:GNIT RS16440
gene id: 1085623:GNIT_RS16440
uniprot id: G4QNE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1085623:GNIT RS14085
gene id: 1085623:GNIT_RS14085
uniprot id: G4QMY2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1085623:GNIT RS15165
gene id: 1085623:GNIT_RS15165
uniprot id: G4QE17
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1085623:GNIT RS07430
gene id: 1085623:GNIT_RS07430
uniprot id: G4QGP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS03340
gene id: 1085623:GNIT_RS03340
uniprot id: G4QFQ7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1085623:GNIT RS05355
gene id: 1085623:GNIT_RS05355
uniprot id: G4QG91
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1085623:GNIT RS10930
gene id: 1085623:GNIT_RS10930
uniprot id: G4QKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS02045
gene id: 1085623:GNIT_RS02045
uniprot id: G4QJI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1085623:GNIT RS08400
gene id: 1085623:GNIT_RS08400
uniprot id: G4QGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1085623:GNIT RS06985
gene id: 1085623:GNIT_RS06985
uniprot id: G4QEQ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1085623:GNIT RS08570
gene id: 1085623:GNIT_RS08570
uniprot id: G4QGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1085623:GNIT RS03140
gene id: 1085623:GNIT_RS03140
uniprot id: G4QFM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1085623:GNIT RS13285
gene id: 1085623:GNIT_RS13285
uniprot id: G4QIH8
names: Similarity
messages: Belongs to the histone deacetylase family.

1085623:GNIT RS06735
gene id: 1085623:GNIT_RS06735
uniprot id: G4QL64
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1085623:GNIT RS04195
gene id: 1085623:GNIT_RS04195
uniprot id: G4QJX8
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS02525
gene id: 1085623:GNIT_RS02525
uniprot id: G4QJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1085623:GNIT RS02445
gene id: 1085623:GNIT_RS02445
uniprot id: G4QJL0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1085623:GNIT RS02580
gene id: 1085623:GNIT_RS02580
uniprot id: G4QJN7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1085623:GNIT RS15145
gene id: 1085623:GNIT_RS15145
uniprot id: G4QE13
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1085623:GNIT RS07010
gene id: 1085623:GNIT_RS07010
uniprot id: G4QEQ5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1085623:GNIT RS12570
gene id: 1085623:GNIT_RS12570
uniprot id: G4QM91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1085623:GNIT RS06565
gene id: 1085623:GNIT_RS06565
uniprot id: G4QL35
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS09950
gene id: 1085623:GNIT_RS09950
uniprot id: G4QH10
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1085623:GNIT RS07400
gene id: 1085623:GNIT_RS07400
uniprot id: G4QGN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS16945
gene id: 1085623:GNIT_RS16945
uniprot id: G4QNW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS13070
gene id: 1085623:GNIT_RS13070
uniprot id: G4QID3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1085623:GNIT RS00865
gene id: 1085623:GNIT_RS00865
uniprot id: G4QIZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1085623:GNIT RS03990
gene id: 1085623:GNIT_RS03990
uniprot id: G4QJT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1085623:GNIT RS07440
gene id: 1085623:GNIT_RS07440
uniprot id: G4QGP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS08190
gene id: 1085623:GNIT_RS08190
uniprot id: G4QLG9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1085623:GNIT RS04350
gene id: 1085623:GNIT_RS04350
uniprot id: G4QFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1085623:GNIT RS00560
gene id: 1085623:GNIT_RS00560
uniprot id: G4QIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1085623:GNIT RS11450
gene id: 1085623:GNIT_RS11450
uniprot id: G4QHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1085623:GNIT RS16985
gene id: 1085623:GNIT_RS16985
uniprot id: G4QNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1085623:GNIT RS07540
gene id: 1085623:GNIT_RS07540
uniprot id: G4QH72
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1085623:GNIT RS10310
gene id: 1085623:GNIT_RS10310
uniprot id: G4QHP1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1085623:GNIT RS08325
gene id: 1085623:GNIT_RS08325
uniprot id: G4QGR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1085623:GNIT RS03770
gene id: 1085623:GNIT_RS03770
uniprot id: G4QJ67
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1085623:GNIT RS15175
gene id: 1085623:GNIT_RS15175
uniprot id: G4QE19
names: Similarity
messages: Belongs to the peptidase U62 family.

1085623:GNIT RS01875
gene id: 1085623:GNIT_RS01875
uniprot id: G4QJE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1085623:GNIT RS06525
gene id: 1085623:GNIT_RS06525
uniprot id: G4QGH2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1085623:GNIT RS03035
gene id: 1085623:GNIT_RS03035
uniprot id: G4QEM5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1085623:GNIT RS15080
gene id: 1085623:GNIT_RS15080
uniprot id: G4QE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS11270
gene id: 1085623:GNIT_RS11270
uniprot id: G4QLX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1085623:GNIT RS01815
gene id: 1085623:GNIT_RS01815
uniprot id: G4QJD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1085623:GNIT RS15915
gene id: 1085623:GNIT_RS15915
uniprot id: G4QN35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1085623:GNIT RS00860
gene id: 1085623:GNIT_RS00860
uniprot id: G4QIZ5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1085623:GNIT RS04125
gene id: 1085623:GNIT_RS04125
uniprot id: G4QJW3
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS13455
gene id: 1085623:GNIT_RS13455
uniprot id: G4QMH5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS14935
gene id: 1085623:GNIT_RS14935
uniprot id: G4QJA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS05590
gene id: 1085623:GNIT_RS05590
uniprot id: G4QKA3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1085623:GNIT RS13075
gene id: 1085623:GNIT_RS13075
uniprot id: G4QID4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1085623:GNIT RS13315
gene id: 1085623:GNIT_RS13315
uniprot id: G4QII4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1085623:GNIT RS04150
gene id: 1085623:GNIT_RS04150
uniprot id: G4QJW8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1085623:GNIT RS03305
gene id: 1085623:GNIT_RS03305
uniprot id: G4QFQ0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1085623:GNIT RS07920
gene id: 1085623:GNIT_RS07920
uniprot id: G4QLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1085623:GNIT RS16620
gene id: 1085623:GNIT_RS16620
uniprot id: G4QNP4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1085623:GNIT RS01540
gene id: 1085623:GNIT_RS01540
uniprot id: G4QFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1085623:GNIT RS08420
gene id: 1085623:GNIT_RS08420
uniprot id: G4QGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1085623:GNIT RS10095
gene id: 1085623:GNIT_RS10095
uniprot id: G4QH40
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1085623:GNIT RS05895
gene id: 1085623:GNIT_RS05895
uniprot id: G4QKX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1085623:GNIT RS11495
gene id: 1085623:GNIT_RS11495
uniprot id: G4QHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1085623:GNIT RS06805
gene id: 1085623:GNIT_RS06805
uniprot id: G4QL81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1085623:GNIT RS15580
gene id: 1085623:GNIT_RS15580
uniprot id: G4QEA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1085623:GNIT RS08430
gene id: 1085623:GNIT_RS08430
uniprot id: G4QGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1085623:GNIT RS02925
gene id: 1085623:GNIT_RS02925
uniprot id: G4QEK4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1085623:GNIT RS01115
gene id: 1085623:GNIT_RS01115
uniprot id: G4QF44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS08735
gene id: 1085623:GNIT_RS08735
uniprot id: G4QHF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1085623:GNIT RS14820
gene id: 1085623:GNIT_RS14820
uniprot id: G4QIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS02515
gene id: 1085623:GNIT_RS02515
uniprot id: G4QJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1085623:GNIT RS07370
gene id: 1085623:GNIT_RS07370
uniprot id: G4QGN1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1085623:GNIT RS14210
gene id: 1085623:GNIT_RS14210
uniprot id: G4QDR1
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS16295
gene id: 1085623:GNIT_RS16295
uniprot id: G4QNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1085623:GNIT RS11685
gene id: 1085623:GNIT_RS11685
uniprot id: G4QI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1085623:GNIT RS06605
gene id: 1085623:GNIT_RS06605
uniprot id: G4QL41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS04760
gene id: 1085623:GNIT_RS04760
uniprot id: G4QK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1085623:GNIT RS11875
gene id: 1085623:GNIT_RS11875
uniprot id: G4QM22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1085623:GNIT RS08040
gene id: 1085623:GNIT_RS08040
uniprot id: G4QLE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1085623:GNIT RS08475
gene id: 1085623:GNIT_RS08475
uniprot id: G4QGU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1085623:GNIT RS02145
gene id: 1085623:GNIT_RS02145
uniprot id: G4QFI2
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1085623:GNIT RS14005
gene id: 1085623:GNIT_RS14005
uniprot id: G4QMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1085623:GNIT RS14430
gene id: 1085623:GNIT_RS14430
uniprot id: G4QDV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1085623:GNIT RS00090
gene id: 1085623:GNIT_RS00090
uniprot id: G4QEF2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1085623:GNIT RS07970
gene id: 1085623:GNIT_RS07970
uniprot id: G4QLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1085623:GNIT RS12835
gene id: 1085623:GNIT_RS12835
uniprot id: G4QME5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1085623:GNIT RS09370
gene id: 1085623:GNIT_RS09370
uniprot id: G4QKL1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1085623:GNIT RS13515
gene id: 1085623:GNIT_RS13515
uniprot id: G4QMI8
names: Subcellular Location Annotation
messages: Periplasm

1085623:GNIT RS12815
gene id: 1085623:GNIT_RS12815
uniprot id: G4QME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1085623:GNIT RS16215
gene id: 1085623:GNIT_RS16215
uniprot id: G4QN98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

1085623:GNIT RS00135
gene id: 1085623:GNIT_RS00135
uniprot id: G4QEG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS06420
gene id: 1085623:GNIT_RS06420
uniprot id: G4QGF1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1085623:GNIT RS08415
gene id: 1085623:GNIT_RS08415
uniprot id: G4QGT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1085623:GNIT RS01150
gene id: 1085623:GNIT_RS01150
uniprot id: G4QF51
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

1085623:GNIT RS11865
gene id: 1085623:GNIT_RS11865
uniprot id: G4QM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS16490
gene id: 1085623:GNIT_RS16490
uniprot id: G4QNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1085623:GNIT RS17490
gene id: 1085623:GNIT_RS17490
uniprot id: G4QNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1085623:GNIT RS02200
gene id: 1085623:GNIT_RS02200
uniprot id: G4QFJ6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1085623:GNIT RS03895
gene id: 1085623:GNIT_RS03895
uniprot id: G4QJS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1085623:GNIT RS10025
gene id: 1085623:GNIT_RS10025
uniprot id: G4QH25
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1085623:GNIT RS11020
gene id: 1085623:GNIT_RS11020
uniprot id: G4QLS4
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS00985
gene id: 1085623:GNIT_RS00985
uniprot id: G4QF16
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1085623:GNIT RS03570
gene id: 1085623:GNIT_RS03570
uniprot id: G4QJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1085623:GNIT RS02360
gene id: 1085623:GNIT_RS02360
uniprot id: G4QJJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1085623:GNIT RS05775
gene id: 1085623:GNIT_RS05775
uniprot id: G4QKE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1085623:GNIT RS00310
gene id: 1085623:GNIT_RS00310
uniprot id: G4QEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1085623:GNIT RS15040
gene id: 1085623:GNIT_RS15040
uniprot id: G4QDZ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1085623:GNIT RS12660
gene id: 1085623:GNIT_RS12660
uniprot id: G4QMA9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1085623:GNIT RS11690
gene id: 1085623:GNIT_RS11690
uniprot id: G4QI19
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS06650
gene id: 1085623:GNIT_RS06650
uniprot id: G4QL47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1085623:GNIT RS11520
gene id: 1085623:GNIT_RS11520
uniprot id: G4QHY1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1085623:GNIT RS11050
gene id: 1085623:GNIT_RS11050
uniprot id: G4QLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1085623:GNIT RS11425
gene id: 1085623:GNIT_RS11425
uniprot id: G4QHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1085623:GNIT RS00280
gene id: 1085623:GNIT_RS00280
uniprot id: G4QEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1085623:GNIT RS08510
gene id: 1085623:GNIT_RS08510
uniprot id: G4QGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1085623:GNIT RS02700
gene id: 1085623:GNIT_RS02700
uniprot id: G4QJR2
names: Subcellular Location Annotation
messages: Cell inner membrane

1085623:GNIT RS14930
gene id: 1085623:GNIT_RS14930
uniprot id: G4QJ99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1085623:GNIT RS02285
gene id: 1085623:GNIT_RS02285
uniprot id: G4QFL3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1085623:GNIT RS11530
gene id: 1085623:GNIT_RS11530
uniprot id: G4QHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1085623:GNIT RS00510
gene id: 1085623:GNIT_RS00510
uniprot id: G4QEZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS09770
gene id: 1085623:GNIT_RS09770
uniprot id: G4QLQ6
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS05715
gene id: 1085623:GNIT_RS05715
uniprot id: G4QKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

1085623:GNIT RS03765
gene id: 1085623:GNIT_RS03765
uniprot id: G4QJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1085623:GNIT RS10445
gene id: 1085623:GNIT_RS10445
uniprot id: G4QHR8
names: Subcellular Location Annotation
messages: Membrane

1085623:GNIT RS02875
gene id: 1085623:GNIT_RS02875
uniprot id: G4QEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1085623:GNIT RS02665
gene id: 1085623:GNIT_RS02665
uniprot id: G4QJQ4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1085623:GNIT RS00385
gene id: 1085623:GNIT_RS00385
uniprot id: G4QEX3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1085623:GNIT RS02170
gene id: 1085623:GNIT_RS02170
uniprot id: G4QFI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS10800
gene id: 1085623:GNIT_RS10800
uniprot id: G4QKR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1085623:GNIT RS05880
gene id: 1085623:GNIT_RS05880
uniprot id: G4QKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1085623:GNIT RS16060
gene id: 1085623:GNIT_RS16060
uniprot id: G4QN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS06215
gene id: 1085623:GNIT_RS06215
uniprot id: G4QGA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1085623:GNIT RS14900
gene id: 1085623:GNIT_RS14900
uniprot id: G4QJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1085623:GNIT RS08360
gene id: 1085623:GNIT_RS08360
uniprot id: G4QGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1085623:GNIT RS02840
gene id: 1085623:GNIT_RS02840
uniprot id: G4QEI7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1085623:GNIT RS02750
gene id: 1085623:GNIT_RS02750
uniprot id: G4QEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1085623:GNIT RS01960
gene id: 1085623:GNIT_RS01960
uniprot id: G4QJG1
names: Similarity
messages: Belongs to the P(II) protein family.

1085623:GNIT RS08355
gene id: 1085623:GNIT_RS08355
uniprot id: G4QGS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS12265
gene id: 1085623:GNIT_RS12265
uniprot id: G4QI63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS03105
gene id: 1085623:GNIT_RS03105
uniprot id: G4QEN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1085623:GNIT RS04230
gene id: 1085623:GNIT_RS04230
uniprot id: G4QJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1085623:GNIT RS13185
gene id: 1085623:GNIT_RS13185
uniprot id: G4QIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1085623:GNIT RS13415
gene id: 1085623:GNIT_RS13415
uniprot id: G4QMG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1085623:GNIT RS06380
gene id: 1085623:GNIT_RS06380
uniprot id: G4QGE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1085623:GNIT RS16145
gene id: 1085623:GNIT_RS16145
uniprot id: G4QN84
names: Similarity
messages: Belongs to the PrpD family.

1085623:GNIT RS16890
gene id: 1085623:GNIT_RS16890
uniprot id: G4QNV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1085623:GNIT RS06335
gene id: 1085623:GNIT_RS06335
uniprot id: G4QGD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1085623:GNIT RS02300
gene id: 1085623:GNIT_RS02300
uniprot id: G4QFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1085623:GNIT RS04810
gene id: 1085623:GNIT_RS04810
uniprot id: G4QK28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1085623:GNIT RS17455
gene id: 1085623:GNIT_RS17455
uniprot id: G4QNI0
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

1085623:GNIT RS12950
gene id: 1085623:GNIT_RS12950
uniprot id: G4QMQ2
names: Subcellular Location Annotation
messages: Cytoplasm

1085623:GNIT RS11230
gene id: 1085623:GNIT_RS11230
uniprot id: G4QLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1085623:GNIT RS11210
gene id: 1085623:GNIT_RS11210
uniprot id: G4QLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1085623:GNIT RS10055
gene id: 1085623:GNIT_RS10055
uniprot id: G4QH31
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS09690
gene id: 1085623:GNIT_RS09690
uniprot id: G4QLN9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1085623:GNIT RS12920
gene id: 1085623:GNIT_RS12920
uniprot id: G4QMP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1085623:GNIT RS14925
gene id: 1085623:GNIT_RS14925
uniprot id: G4QJ98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1085623:GNIT RS08550
gene id: 1085623:GNIT_RS08550
uniprot id: G4QGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1085623:GNIT RS09510
gene id: 1085623:GNIT_RS09510
uniprot id: G4QLK1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1085623:GNIT RS02900
gene id: 1085623:GNIT_RS02900
uniprot id: G4QEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1085623:GNIT RS09990
gene id: 1085623:GNIT_RS09990
uniprot id: G4QH18
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1085623:GNIT RS10955
gene id: 1085623:GNIT_RS10955
uniprot id: G4QKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1085623:GNIT RS01660
gene id: 1085623:GNIT_RS01660
uniprot id: G4QFG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1085623:GNIT RS14370
gene id: 1085623:GNIT_RS14370
uniprot id: G4QDU7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1085623:GNIT RS01375
gene id: 1085623:GNIT_RS01375
uniprot id: G4QF98
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1085623:GNIT RS14105
gene id: 1085623:GNIT_RS14105
uniprot id: G4QMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1085623:GNIT RS16115
gene id: 1085623:GNIT_RS16115
uniprot id: G4QN78
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1085623:GNIT RS12980
gene id: 1085623:GNIT_RS12980
uniprot id: G4QMP8
names: Similarity
messages: Belongs to the transketolase family.

1085623:GNIT RS09110
gene id: 1085623:GNIT_RS09110
uniprot id: G4QKF7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1085623:GNIT RS14655
gene id: 1085623:GNIT_RS14655
uniprot id: G4QIN0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1085623:GNIT RS11605
gene id: 1085623:GNIT_RS11605
uniprot id: G4QI00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1085623:GNIT RS11125
gene id: 1085623:GNIT_RS11125
uniprot id: G4QLU2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1085623:GNIT RS10980
gene id: 1085623:GNIT_RS10980
uniprot id: G4QKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1085623:GNIT RS00110
gene id: 1085623:GNIT_RS00110
uniprot id: G4QEF6
names: Similarity
messages: Belongs to the Smg family.

1085623:GNIT RS10275
gene id: 1085623:GNIT_RS10275
uniprot id: G4QHN3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1085623:GNIT RS01440
gene id: 1085623:GNIT_RS01440
uniprot id: G4QFB2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1085623:GNIT RS09955
gene id: 1085623:GNIT_RS09955
uniprot id: G4QH11
names: Similarity
messages: Belongs to the asparaginase 1 family.

1085623:GNIT RS02060
gene id: 1085623:GNIT_RS02060
uniprot id: G4QFG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.