1076588:TBH RS12955
gene id: 1076588:TBH_RS12955
uniprot id: A0A7U6GKY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1076588:TBH RS02550
gene id: 1076588:TBH_RS02550
uniprot id: A0A7U6JHQ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1076588:TBH RS11750
gene id: 1076588:TBH_RS11750
uniprot id: A0A7U6JIT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1076588:TBH RS00055
gene id: 1076588:TBH_RS00055
uniprot id: A0A7U6GG17
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1076588:TBH RS02885
gene id: 1076588:TBH_RS02885
uniprot id: A0A7U6GH37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1076588:TBH RS09475
gene id: 1076588:TBH_RS09475
uniprot id: A0A7U6GJE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1076588:TBH RS13750
gene id: 1076588:TBH_RS13750
uniprot id: A0A7U6GL29
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS07935
gene id: 1076588:TBH_RS07935
uniprot id: A0A7U6JIQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1076588:TBH RS05430
gene id: 1076588:TBH_RS05430
uniprot id: A0A7U6GHY3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1076588:TBH RS02235
gene id: 1076588:TBH_RS02235
uniprot id: A0A7U6GGU1
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1076588:TBH RS04830
gene id: 1076588:TBH_RS04830
uniprot id: A0A7U6GHS7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1076588:TBH RS05265
gene id: 1076588:TBH_RS05265
uniprot id: A0A7U6GHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1076588:TBH RS14335
gene id: 1076588:TBH_RS14335
uniprot id: A0A7U6GL43
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1076588:TBH RS05355
gene id: 1076588:TBH_RS05355
uniprot id: A0A7U6GI05
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1076588:TBH RS08900
gene id: 1076588:TBH_RS08900
uniprot id: A0A7U6GJ75
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1076588:TBH RS07850
gene id: 1076588:TBH_RS07850
uniprot id: A0A7U6JHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1076588:TBH RS09140
gene id: 1076588:TBH_RS09140
uniprot id: A0A7U6GJF1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1076588:TBH RS00845
gene id: 1076588:TBH_RS00845
uniprot id: A0A7U6GGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1076588:TBH RS07945
gene id: 1076588:TBH_RS07945
uniprot id: A0A7U6GIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1076588:TBH RS07990
gene id: 1076588:TBH_RS07990
uniprot id: A0A7U6JHL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1076588:TBH RS04595
gene id: 1076588:TBH_RS04595
uniprot id: A0A7U6JI34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS04565
gene id: 1076588:TBH_RS04565
uniprot id: A0A7U6GHL7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1076588:TBH RS12325
gene id: 1076588:TBH_RS12325
uniprot id: A0A7U6GKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS07040
gene id: 1076588:TBH_RS07040
uniprot id: A0A7U6GIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1076588:TBH RS00050
gene id: 1076588:TBH_RS00050
uniprot id: A0A7U6GG01
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1076588:TBH RS09280
gene id: 1076588:TBH_RS09280
uniprot id: A0A7U6JIE4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1076588:TBH RS14715
gene id: 1076588:TBH_RS14715
uniprot id: A0A7U6GLA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS01125
gene id: 1076588:TBH_RS01125
uniprot id: A0A7U6JGR7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1076588:TBH RS06275
gene id: 1076588:TBH_RS06275
uniprot id: A0A7U6GIB1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1076588:TBH RS01260
gene id: 1076588:TBH_RS01260
uniprot id: A0A7U6GGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1076588:TBH RS00785
gene id: 1076588:TBH_RS00785
uniprot id: A0A7U6GG95
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1076588:TBH RS04080
gene id: 1076588:TBH_RS04080
uniprot id: A0A7U6GHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1076588:TBH RS10030
gene id: 1076588:TBH_RS10030
uniprot id: A0A7U6GJM0
names: Similarity
messages: Belongs to the aspartokinase family.

1076588:TBH RS12260
gene id: 1076588:TBH_RS12260
uniprot id: A0A7U6GKJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1076588:TBH RS08550
gene id: 1076588:TBH_RS08550
uniprot id: A0A7U6GJ34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1076588:TBH RS06250
gene id: 1076588:TBH_RS06250
uniprot id: A0A7U6JH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS07795
gene id: 1076588:TBH_RS07795
uniprot id: A0A7U6GIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1076588:TBH RS04005
gene id: 1076588:TBH_RS04005
uniprot id: A0A7U6GHG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1076588:TBH RS10315
gene id: 1076588:TBH_RS10315
uniprot id: A0A7U6GJT5
names: Similarity
messages: Belongs to the universal stress protein A family.

1076588:TBH RS10975
gene id: 1076588:TBH_RS10975
uniprot id: A0A7U6GJY3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1076588:TBH RS02880
gene id: 1076588:TBH_RS02880
uniprot id: A0A7U6GH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1076588:TBH RS05925
gene id: 1076588:TBH_RS05925
uniprot id: A0A7U6JHU6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1076588:TBH RS08745
gene id: 1076588:TBH_RS08745
uniprot id: A0A7U6GJ86
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1076588:TBH RS01525
gene id: 1076588:TBH_RS01525
uniprot id: A0A7U6GGJ6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1076588:TBH RS02720
gene id: 1076588:TBH_RS02720
uniprot id: A0A7U6GH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS04180
gene id: 1076588:TBH_RS04180
uniprot id: A0A7U6JHG0
names: Similarity
messages: Belongs to the transposase 8 family.

1076588:TBH RS07340
gene id: 1076588:TBH_RS07340
uniprot id: A0A7U6GIP3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1076588:TBH RS10540
gene id: 1076588:TBH_RS10540
uniprot id: A0A7U6JHY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1076588:TBH RS05625
gene id: 1076588:TBH_RS05625
uniprot id: A0A7U6GI39
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1076588:TBH RS06170
gene id: 1076588:TBH_RS06170
uniprot id: A0A7U6JH44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1076588:TBH RS01855
gene id: 1076588:TBH_RS01855
uniprot id: A0A7U6JHK3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1076588:TBH RS02165
gene id: 1076588:TBH_RS02165
uniprot id: A0A7U6GGS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1076588:TBH RS07060
gene id: 1076588:TBH_RS07060
uniprot id: A0A7U6GIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1076588:TBH RS10955
gene id: 1076588:TBH_RS10955
uniprot id: A0A7U6GJZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1076588:TBH RS13510
gene id: 1076588:TBH_RS13510
uniprot id: A0A7U6GKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1076588:TBH RS09945
gene id: 1076588:TBH_RS09945
uniprot id: A0A7U6GJH8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1076588:TBH RS02955
gene id: 1076588:TBH_RS02955
uniprot id: A0A7U6GH33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1076588:TBH RS13285
gene id: 1076588:TBH_RS13285
uniprot id: A0A7U6GKS3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1076588:TBH RS05580
gene id: 1076588:TBH_RS05580
uniprot id: A0A7U6GI08
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1076588:TBH RS07200
gene id: 1076588:TBH_RS07200
uniprot id: A0A7U6GIN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1076588:TBH RS08585
gene id: 1076588:TBH_RS08585
uniprot id: A0A7U6GJ38
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS06620
gene id: 1076588:TBH_RS06620
uniprot id: A0A7U6JH85
names: Similarity
messages: Belongs to the TrpF family.

1076588:TBH RS09715
gene id: 1076588:TBH_RS09715
uniprot id: A0A7U6GJE4
names: Similarity
messages: Belongs to the GppA/Ppx family.

1076588:TBH RS10390
gene id: 1076588:TBH_RS10390
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS05855
gene id: 1076588:TBH_RS05855
uniprot id: A0A7U6JIB5
names: Similarity
messages: Belongs to the YkuD family.

1076588:TBH RS07900
gene id: 1076588:TBH_RS07900
uniprot id: A0A7U6GIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1076588:TBH RS05745
gene id: 1076588:TBH_RS05745
uniprot id: A0A7U6GI29
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02310
gene id: 1076588:TBH_RS02310
uniprot id: A0A7U6GGU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS02030
gene id: 1076588:TBH_RS02030
uniprot id: A0A7U6GGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1076588:TBH RS02710
gene id: 1076588:TBH_RS02710
uniprot id: A0A7U6GH00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1076588:TBH RS09320
gene id: 1076588:TBH_RS09320
uniprot id: A0A7U6GJC7
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS09780
gene id: 1076588:TBH_RS09780
uniprot id: A0A7U6GJM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1076588:TBH RS05930
gene id: 1076588:TBH_RS05930
uniprot id: A0A7U6JH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1076588:TBH RS05365
gene id: 1076588:TBH_RS05365
uniprot id: A0A7U6GHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1076588:TBH RS02115
gene id: 1076588:TBH_RS02115
uniprot id: A0A7U6GGQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1076588:TBH RS04345
gene id: 1076588:TBH_RS04345
uniprot id: A0A7U6JGQ7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1076588:TBH RS03670
gene id: 1076588:TBH_RS03670
uniprot id: A0A7U6GHB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1076588:TBH RS03740
gene id: 1076588:TBH_RS03740
uniprot id: A0A7U6GHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS06040
gene id: 1076588:TBH_RS06040
uniprot id: A0A7U6GI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1076588:TBH RS09865
gene id: 1076588:TBH_RS09865
uniprot id: A0A7U6GJG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS02940
gene id: 1076588:TBH_RS02940
uniprot id: A0A7U6GH72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1076588:TBH RS12900
gene id: 1076588:TBH_RS12900
uniprot id: A0A7U6GKQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS11985
gene id: 1076588:TBH_RS11985
uniprot id: A0A7U6JIY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1076588:TBH RS02475
gene id: 1076588:TBH_RS02475
uniprot id: A0A7U6JHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS13945
gene id: 1076588:TBH_RS13945
uniprot id: A0A7U6JIS3
names: Similarity
messages: Belongs to the UPF0246 family.

1076588:TBH RS13185
gene id: 1076588:TBH_RS13185
uniprot id: A0A7U6GKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1076588:TBH RS09090
gene id: 1076588:TBH_RS09090
uniprot id: A0A7U6GJB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1076588:TBH RS11430
gene id: 1076588:TBH_RS11430
uniprot id: A0A7U6GK79
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS04750
gene id: 1076588:TBH_RS04750
uniprot id: A0A7U6JI45
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1076588:TBH RS08620
gene id: 1076588:TBH_RS08620
uniprot id: A0A7U6GJ05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1076588:TBH RS05485
gene id: 1076588:TBH_RS05485
uniprot id: A0A7U6GI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1076588:TBH RS01735
gene id: 1076588:TBH_RS01735
uniprot id: A0A7U6GGN8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1076588:TBH RS10670
gene id: 1076588:TBH_RS10670
uniprot id: A0A7U6GJY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1076588:TBH RS07055
gene id: 1076588:TBH_RS07055
uniprot id: A0A7U6GIK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1076588:TBH RS01880
gene id: 1076588:TBH_RS01880
uniprot id: A0A7U6GGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS00145
gene id: 1076588:TBH_RS00145
uniprot id: A0A7U6GG25
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS05310
gene id: 1076588:TBH_RS05310
uniprot id: A0A7U6JI79
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1076588:TBH RS13965
gene id: 1076588:TBH_RS13965
uniprot id: A0A7U6JL74
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1076588:TBH RS06185
gene id: 1076588:TBH_RS06185
uniprot id: A0A7U6GIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1076588:TBH RS11170
gene id: 1076588:TBH_RS11170
uniprot id: A0A7U6GK15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1076588:TBH RS00280
gene id: 1076588:TBH_RS00280
uniprot id: A0A7U6JHA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1076588:TBH RS06880
gene id: 1076588:TBH_RS06880
uniprot id: A0A7U6GIJ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1076588:TBH RS00835
gene id: 1076588:TBH_RS00835
uniprot id: A0A7U6GGB5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1076588:TBH RS01785
gene id: 1076588:TBH_RS01785
uniprot id: A0A7U6GGN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1076588:TBH RS01200
gene id: 1076588:TBH_RS01200
uniprot id: A0A7U6JGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1076588:TBH RS04710
gene id: 1076588:TBH_RS04710
uniprot id: A0A7U6GHS0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1076588:TBH RS10880
gene id: 1076588:TBH_RS10880
uniprot id: A0A7U6GJY8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1076588:TBH RS10590
gene id: 1076588:TBH_RS10590
uniprot id: A0A7U6GJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1076588:TBH RS05135
gene id: 1076588:TBH_RS05135
uniprot id: A0A7U6GHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS14795
gene id: 1076588:TBH_RS14795
uniprot id: A0A7U6GLB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1076588:TBH RS12105
gene id: 1076588:TBH_RS12105
uniprot id: A0A7U6GKC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1076588:TBH RS09630
gene id: 1076588:TBH_RS09630
uniprot id: A0A7U6GJH3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1076588:TBH RS00540
gene id: 1076588:TBH_RS00540
uniprot id: A0A7U6GG79
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1076588:TBH RS01185
gene id: 1076588:TBH_RS01185
uniprot id: A0A7U6GGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1076588:TBH RS03590
gene id: 1076588:TBH_RS03590
uniprot id: A0A7U6GHD0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1076588:TBH RS15005
gene id: 1076588:TBH_RS15005
uniprot id: A0A7U6GGF3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1076588:TBH RS02850
gene id: 1076588:TBH_RS02850
uniprot id: A0A7U6JHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1076588:TBH RS06590
gene id: 1076588:TBH_RS06590
uniprot id: A0A7U6GID4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1076588:TBH RS08270
gene id: 1076588:TBH_RS08270
uniprot id: A0A7U6JHI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS11570
gene id: 1076588:TBH_RS11570
uniprot id: A0A7U6GK58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1076588:TBH RS08895
gene id: 1076588:TBH_RS08895
uniprot id: A0A7U6JIW5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS10045
gene id: 1076588:TBH_RS10045
uniprot id: A0A7U6GJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1076588:TBH RS10570
gene id: 1076588:TBH_RS10570
uniprot id: A0A7U6GJT1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1076588:TBH RS12510
gene id: 1076588:TBH_RS12510
uniprot id: A0A7U6JII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS12830
gene id: 1076588:TBH_RS12830
uniprot id: A0A7U6JJ26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS09740
gene id: 1076588:TBH_RS09740
uniprot id: A0A7U6JHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1076588:TBH RS07365
gene id: 1076588:TBH_RS07365
uniprot id: A0A7U6GIM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1076588:TBH RS05575
gene id: 1076588:TBH_RS05575
uniprot id: A0A7U6GI36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1076588:TBH RS07865
gene id: 1076588:TBH_RS07865
uniprot id: A0A7U6GIY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1076588:TBH RS09440
gene id: 1076588:TBH_RS09440
uniprot id: A0A7U6JIF4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1076588:TBH RS02415
gene id: 1076588:TBH_RS02415
uniprot id: A0A7U6GGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1076588:TBH RS06720
gene id: 1076588:TBH_RS06720
uniprot id: A0A7U6GIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1076588:TBH RS00665
gene id: 1076588:TBH_RS00665
uniprot id: A0A7U6JFM3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1076588:TBH RS05950
gene id: 1076588:TBH_RS05950
uniprot id: A0A7U6GI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1076588:TBH RS12460
gene id: 1076588:TBH_RS12460
uniprot id: A0A7U6GKL3
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS16305
gene id: 1076588:TBH_RS16305
uniprot id: A0A7U6GL08
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1076588:TBH RS04290
gene id: 1076588:TBH_RS04290
uniprot id: A0A7U6GHM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1076588:TBH RS04200
gene id: 1076588:TBH_RS04200
uniprot id: A0A7U6GHJ4
names: Similarity
messages: Belongs to the UPF0423 family.

1076588:TBH RS03115
gene id: 1076588:TBH_RS03115
uniprot id: A0A7U6GH90
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS14140
gene id: 1076588:TBH_RS14140
uniprot id: A0A7U6JIK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1076588:TBH RS01890
gene id: 1076588:TBH_RS01890
uniprot id: A0A7U6GGN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1076588:TBH RS12995
gene id: 1076588:TBH_RS12995
uniprot id: A0A7U6JJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1076588:TBH RS06200
gene id: 1076588:TBH_RS06200
uniprot id: A0A7U6GI98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1076588:TBH RS00595
gene id: 1076588:TBH_RS00595
uniprot id: A0A7U6JHC3
names: Similarity
messages: Belongs to the NodU/CmcH family.

1076588:TBH RS10850
gene id: 1076588:TBH_RS10850
uniprot id: A0A7U6JIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1076588:TBH RS02040
gene id: 1076588:TBH_RS02040
uniprot id: A0A7U6GGP3
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS09605
gene id: 1076588:TBH_RS09605
uniprot id: A0A7U6JJ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1076588:TBH RS00430
gene id: 1076588:TBH_RS00430
uniprot id: A0A7U6JHB3
names: Similarity
messages: Belongs to the thioredoxin family.

1076588:TBH RS07005
gene id: 1076588:TBH_RS07005
uniprot id: A0A7U6JHG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1076588:TBH RS05350
gene id: 1076588:TBH_RS05350
uniprot id: A0A7U6GHY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1076588:TBH RS05750
gene id: 1076588:TBH_RS05750
uniprot id: A0A7U6GI24
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1076588:TBH RS05700
gene id: 1076588:TBH_RS05700
uniprot id: A0A7U6GI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1076588:TBH RS14130
gene id: 1076588:TBH_RS14130
uniprot id: A0A7U6JJI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1076588:TBH RS00030
gene id: 1076588:TBH_RS00030
uniprot id: A0A7U6GG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1076588:TBH RS09345
gene id: 1076588:TBH_RS09345
uniprot id: A0A7U6GJI2
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS10000
gene id: 1076588:TBH_RS10000
uniprot id: A0A7U6GJP7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1076588:TBH RS07075
gene id: 1076588:TBH_RS07075
uniprot id: A0A7U6GIM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1076588:TBH RS03735
gene id: 1076588:TBH_RS03735
uniprot id: A0A7U6GHG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1076588:TBH RS12920
gene id: 1076588:TBH_RS12920
uniprot id: A0A7U6JJ99
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1076588:TBH RS11345
gene id: 1076588:TBH_RS11345
uniprot id: A0A7U6GK14
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS02085
gene id: 1076588:TBH_RS02085
uniprot id: A0A7U6GGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1076588:TBH RS06300
gene id: 1076588:TBH_RS06300
uniprot id: A0A7U6GIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS06530
gene id: 1076588:TBH_RS06530
uniprot id: A0A7U6JHD4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1076588:TBH RS07115
gene id: 1076588:TBH_RS07115
uniprot id: A0A7U6GIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1076588:TBH RS10690
gene id: 1076588:TBH_RS10690
uniprot id: A0A7U6JHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1076588:TBH RS05645
gene id: 1076588:TBH_RS05645
uniprot id: A0A7U6GI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS05275
gene id: 1076588:TBH_RS05275
uniprot id: A0A7U6GHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS08690
gene id: 1076588:TBH_RS08690
uniprot id: A0A7U6GJ17
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1076588:TBH RS06255
gene id: 1076588:TBH_RS06255
uniprot id: A0A7U6JIE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS06265
gene id: 1076588:TBH_RS06265
uniprot id: A0A7U6GIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS05770
gene id: 1076588:TBH_RS05770
uniprot id: A0A7U6JHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1076588:TBH RS07020
gene id: 1076588:TBH_RS07020
uniprot id: A0A7U6JHB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1076588:TBH RS03360
gene id: 1076588:TBH_RS03360
uniprot id: A0A7U6GH96
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1076588:TBH RS07810
gene id: 1076588:TBH_RS07810
uniprot id: A0A7U6GIS3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1076588:TBH RS08130
gene id: 1076588:TBH_RS08130
uniprot id: A0A7U6GIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1076588:TBH RS05095
gene id: 1076588:TBH_RS05095
uniprot id: A0A7U6GHW9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1076588:TBH RS04770
gene id: 1076588:TBH_RS04770
uniprot id: A0A7U6GHT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS09515
gene id: 1076588:TBH_RS09515
uniprot id: A0A7U6JHW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1076588:TBH RS05985
gene id: 1076588:TBH_RS05985
uniprot id: A0A7U6GI85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1076588:TBH RS08275
gene id: 1076588:TBH_RS08275
uniprot id: A0A7U6JIR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS07025
gene id: 1076588:TBH_RS07025
uniprot id: A0A7U6JIJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1076588:TBH RS07965
gene id: 1076588:TBH_RS07965
uniprot id: A0A7U6GIT9
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1076588:TBH RS06585
gene id: 1076588:TBH_RS06585
uniprot id: A0A7U6GIG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1076588:TBH RS06135
gene id: 1076588:TBH_RS06135
uniprot id: A0A7U6GI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1076588:TBH RS07695
gene id: 1076588:TBH_RS07695
uniprot id: A0A7U6GIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1076588:TBH RS05535
gene id: 1076588:TBH_RS05535
uniprot id: A0A7U6JGY8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1076588:TBH RS06570
gene id: 1076588:TBH_RS06570
uniprot id: A0A7U6GIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS01165
gene id: 1076588:TBH_RS01165
uniprot id: A0A7U6GGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1076588:TBH RS07950
gene id: 1076588:TBH_RS07950
uniprot id: A0A7U6GIZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1076588:TBH RS13250
gene id: 1076588:TBH_RS13250
uniprot id: A0A7U6JKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS11470
gene id: 1076588:TBH_RS11470
uniprot id: A0A7U6GK81
names: Similarity
messages: Belongs to the pyruvate kinase family.

1076588:TBH RS04245
gene id: 1076588:TBH_RS04245
uniprot id: A0A7U6JGV9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1076588:TBH RS14095
gene id: 1076588:TBH_RS14095
uniprot id: A0A7U6GL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1076588:TBH RS12500
gene id: 1076588:TBH_RS12500
uniprot id: A0A7U6GKM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1076588:TBH RS04110
gene id: 1076588:TBH_RS04110
uniprot id: A0A7U6JGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1076588:TBH RS05595
gene id: 1076588:TBH_RS05595
uniprot id: A0A7U6JH63
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1076588:TBH RS02545
gene id: 1076588:TBH_RS02545
uniprot id: A0A7U6JG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS02495
gene id: 1076588:TBH_RS02495
uniprot id: A0A7U6GH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS01385
gene id: 1076588:TBH_RS01385
uniprot id: A0A7U6GGI9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1076588:TBH RS05920
gene id: 1076588:TBH_RS05920
uniprot id: A0A7U6JHR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1076588:TBH RS14480
gene id: 1076588:TBH_RS14480
uniprot id: A0A7U6JIM7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

1076588:TBH RS13300
gene id: 1076588:TBH_RS13300
uniprot id: A0A7U6GKW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1076588:TBH RS09815
gene id: 1076588:TBH_RS09815
uniprot id: A0A7U6JI00
names: Similarity
messages: Belongs to the YfgM family.

1076588:TBH RS07190
gene id: 1076588:TBH_RS07190
uniprot id: A0A7U6GIN0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1076588:TBH RS11595
gene id: 1076588:TBH_RS11595
uniprot id: A0A7U6GK84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1076588:TBH RS01170
gene id: 1076588:TBH_RS01170
uniprot id: A0A7U6GGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1076588:TBH RS07240
gene id: 1076588:TBH_RS07240
uniprot id: A0A7U6JI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1076588:TBH RS04340
gene id: 1076588:TBH_RS04340
uniprot id: A0A7U6JHK1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1076588:TBH RS13140
gene id: 1076588:TBH_RS13140
uniprot id: A0A7U6GKT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1076588:TBH RS08675
gene id: 1076588:TBH_RS08675
uniprot id: A0A7U6GJ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1076588:TBH RS11340
gene id: 1076588:TBH_RS11340
uniprot id: A0A7U6GK31
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS12670
gene id: 1076588:TBH_RS12670
uniprot id: A0A7U6JJ60
names: Similarity
messages: Belongs to the DsrF/TusC family.

1076588:TBH RS02840
gene id: 1076588:TBH_RS02840
uniprot id: A0A7U6JHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1076588:TBH RS06240
gene id: 1076588:TBH_RS06240
uniprot id: A0A7U6JHW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1076588:TBH RS13800
gene id: 1076588:TBH_RS13800
uniprot id: A0A7U6JJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1076588:TBH RS01550
gene id: 1076588:TBH_RS01550
uniprot id: A0A7U6JFW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1076588:TBH RS02105
gene id: 1076588:TBH_RS02105
uniprot id: A0A7U6GGV3
names: Similarity
messages: Belongs to the DprA/Smf family.

1076588:TBH RS06655
gene id: 1076588:TBH_RS06655
uniprot id: A0A7U6GIF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS12180
gene id: 1076588:TBH_RS12180
uniprot id: A0A7U6GKC8
names: Similarity
messages: Belongs to the P(II) protein family.

1076588:TBH RS12935
gene id: 1076588:TBH_RS12935
uniprot id: A0A7U6GKL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1076588:TBH RS14645
gene id: 1076588:TBH_RS14645
uniprot id: A0A7U6GLE5
names: Subcellular Location Annotation
messages: Cytoplasm

1076588:TBH RS01195
gene id: 1076588:TBH_RS01195
uniprot id: A0A7U6JFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1076588:TBH RS11190
gene id: 1076588:TBH_RS11190
uniprot id: A0A7U6GK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1076588:TBH RS12985
gene id: 1076588:TBH_RS12985
uniprot id: A0A7U6GKS6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1076588:TBH RS04370
gene id: 1076588:TBH_RS04370
uniprot id: A0A7U6GHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1076588:TBH RS08505
gene id: 1076588:TBH_RS08505
uniprot id: A0A7U6JIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS08985
gene id: 1076588:TBH_RS08985
uniprot id: A0A7U6GJD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1076588:TBH RS05110
gene id: 1076588:TBH_RS05110
uniprot id: A0A7U6GHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS02705
gene id: 1076588:TBH_RS02705
uniprot id: A0A7U6GGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1076588:TBH RS01720
gene id: 1076588:TBH_RS01720
uniprot id: A0A7U6GGP4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1076588:TBH RS07110
gene id: 1076588:TBH_RS07110
uniprot id: A0A7U6GIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1076588:TBH RS13370
gene id: 1076588:TBH_RS13370
uniprot id: A0A7U6GKW1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1076588:TBH RS02620
gene id: 1076588:TBH_RS02620
uniprot id: A0A7U6JG85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1076588:TBH RS08150
gene id: 1076588:TBH_RS08150
uniprot id: A0A7U6GIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1076588:TBH RS08855
gene id: 1076588:TBH_RS08855
uniprot id: A0A7U6GJ91
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1076588:TBH RS03665
gene id: 1076588:TBH_RS03665
uniprot id: A0A7U6GHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1076588:TBH RS11330
gene id: 1076588:TBH_RS11330
uniprot id: A0A7U6GK94
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1076588:TBH RS01570
gene id: 1076588:TBH_RS01570
uniprot id: A0A7U6GGM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1076588:TBH RS05995
gene id: 1076588:TBH_RS05995
uniprot id: A0A7U6JHS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1076588:TBH RS02750
gene id: 1076588:TBH_RS02750
uniprot id: A0A7U6GGZ6
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02760
gene id: 1076588:TBH_RS02760
uniprot id: A0A7U6JH49
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS04625
gene id: 1076588:TBH_RS04625
uniprot id: A0A7U6GHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1076588:TBH RS00340
gene id: 1076588:TBH_RS00340
uniprot id: A0A7U6JGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1076588:TBH RS10845
gene id: 1076588:TBH_RS10845
uniprot id: A0A7U6JI66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1076588:TBH RS01535
gene id: 1076588:TBH_RS01535
uniprot id: A0A7U6JG35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1076588:TBH RS06840
gene id: 1076588:TBH_RS06840
uniprot id: A0A7U6JHX6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1076588:TBH RS00805
gene id: 1076588:TBH_RS00805
uniprot id: A0A7U6JFV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1076588:TBH RS00300
gene id: 1076588:TBH_RS00300
uniprot id: A0A7U6GG62
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS11925
gene id: 1076588:TBH_RS11925
uniprot id: A0A7U6GKE5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1076588:TBH RS04655
gene id: 1076588:TBH_RS04655
uniprot id: A0A7U6JGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS07660
gene id: 1076588:TBH_RS07660
uniprot id: A0A7U6JI27
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1076588:TBH RS08720
gene id: 1076588:TBH_RS08720
uniprot id: A0A7U6JI94
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1076588:TBH RS13165
gene id: 1076588:TBH_RS13165
uniprot id: A0A7U6JIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1076588:TBH RS02080
gene id: 1076588:TBH_RS02080
uniprot id: A0A7U6JHM0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1076588:TBH RS13425
gene id: 1076588:TBH_RS13425
uniprot id: A0A7U6GKV5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1076588:TBH RS00515
gene id: 1076588:TBH_RS00515
uniprot id: A0A7U6JHB8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1076588:TBH RS01770
gene id: 1076588:TBH_RS01770
uniprot id: A0A7U6JH02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1076588:TBH RS08310
gene id: 1076588:TBH_RS08310
uniprot id: A0A7U6GJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS03265
gene id: 1076588:TBH_RS03265
uniprot id: A0A7U6GHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1076588:TBH RS06145
gene id: 1076588:TBH_RS06145
uniprot id: A0A7U6GI79
names: Similarity
messages: Belongs to the peptidase M1 family.

1076588:TBH RS10930
gene id: 1076588:TBH_RS10930
uniprot id: A0A7U6JIP4
names: Similarity
messages: Belongs to the PhoH family.

1076588:TBH RS15955
gene id: 1076588:TBH_RS15955
uniprot id: A0A7U6GJX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1076588:TBH RS10825
gene id: 1076588:TBH_RS10825
uniprot id: A0A7U6GJW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1076588:TBH RS11820
gene id: 1076588:TBH_RS11820
uniprot id: A0A7U6JID7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS02805
gene id: 1076588:TBH_RS02805
uniprot id: A0A7U6GH13
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1076588:TBH RS04010
gene id: 1076588:TBH_RS04010
uniprot id: A0A7U6GHE6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1076588:TBH RS00965
gene id: 1076588:TBH_RS00965
uniprot id: A0A7U6JGQ6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1076588:TBH RS08120
gene id: 1076588:TBH_RS08120
uniprot id: A0A7U6GJ12
names: Similarity
messages: Belongs to the UPF0434 family.

1076588:TBH RS09195
gene id: 1076588:TBH_RS09195
uniprot id: A0A7U6JID6
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1076588:TBH RS05235
gene id: 1076588:TBH_RS05235
uniprot id: A0A7U6JI72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1076588:TBH RS11955
gene id: 1076588:TBH_RS11955
uniprot id: A0A7U6GKD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1076588:TBH RS00400
gene id: 1076588:TBH_RS00400
uniprot id: A0A7U6GG57
names: Similarity
messages: Belongs to the GARS family.

1076588:TBH RS10160
gene id: 1076588:TBH_RS10160
uniprot id: A0A7U6GJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS00810
gene id: 1076588:TBH_RS00810
uniprot id: A0A7U6JGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1076588:TBH RS02640
gene id: 1076588:TBH_RS02640
uniprot id: A0A7U6GH27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1076588:TBH RS01035
gene id: 1076588:TBH_RS01035
uniprot id: A0A7U6GGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1076588:TBH RS10580
gene id: 1076588:TBH_RS10580
uniprot id: A0A7U6GJT9
names: Similarity
messages: Belongs to the peptidase M16 family.

1076588:TBH RS08115
gene id: 1076588:TBH_RS08115
uniprot id: A0A7U6GJ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1076588:TBH RS08725
gene id: 1076588:TBH_RS08725
uniprot id: A0A7U6JIA9
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1076588:TBH RS03775
gene id: 1076588:TBH_RS03775
uniprot id: A0A7U6JGR1
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS01700
gene id: 1076588:TBH_RS01700
uniprot id: A0A7U6JFY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1076588:TBH RS05055
gene id: 1076588:TBH_RS05055
uniprot id: A0A7U6GHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1076588:TBH RS03255
gene id: 1076588:TBH_RS03255
uniprot id: A0A7U6GH56
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS12040
gene id: 1076588:TBH_RS12040
uniprot id: A0A7U6GKF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1076588:TBH RS08240
gene id: 1076588:TBH_RS08240
uniprot id: A0A7U6GJ37
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1076588:TBH RS00825
gene id: 1076588:TBH_RS00825
uniprot id: A0A7U6JHD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1076588:TBH RS09860
gene id: 1076588:TBH_RS09860
uniprot id: A0A7U6GJJ8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1076588:TBH RS00480
gene id: 1076588:TBH_RS00480
uniprot id: A0A7U6GG67
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1076588:TBH RS06630
gene id: 1076588:TBH_RS06630
uniprot id: A0A7U6GID7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1076588:TBH RS06850
gene id: 1076588:TBH_RS06850
uniprot id: A0A7U6JHA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS00815
gene id: 1076588:TBH_RS00815
uniprot id: A0A7U6JGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1076588:TBH RS07970
gene id: 1076588:TBH_RS07970
uniprot id: A0A7U6GIW9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1076588:TBH RS05185
gene id: 1076588:TBH_RS05185
uniprot id: A0A7U6GHW8
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS07170
gene id: 1076588:TBH_RS07170
uniprot id: A0A7U6JI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1076588:TBH RS02025
gene id: 1076588:TBH_RS02025
uniprot id: A0A7U6GGV9
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS00305
gene id: 1076588:TBH_RS00305
uniprot id: A0A7U6GG56
names: Similarity
messages: Belongs to the TrpC family.

1076588:TBH RS03275
gene id: 1076588:TBH_RS03275
uniprot id: A0A7U6GH87
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1076588:TBH RS14125
gene id: 1076588:TBH_RS14125
uniprot id: A0A7U6JIT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1076588:TBH RS13295
gene id: 1076588:TBH_RS13295
uniprot id: A0A7U6GKV6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1076588:TBH RS04675
gene id: 1076588:TBH_RS04675
uniprot id: A0A7U6JI39
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1076588:TBH RS06560
gene id: 1076588:TBH_RS06560
uniprot id: A0A7U6GIG1
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS03485
gene id: 1076588:TBH_RS03485
uniprot id: A0A7U6GH94
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1076588:TBH RS10435
gene id: 1076588:TBH_RS10435
uniprot id: A0A7U6GJN2
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02095
gene id: 1076588:TBH_RS02095
uniprot id: A0A7U6GGV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1076588:TBH RS08165
gene id: 1076588:TBH_RS08165
uniprot id: A0A7U6JHM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1076588:TBH RS02175
gene id: 1076588:TBH_RS02175
uniprot id: A0A7U6GGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1076588:TBH RS12170
gene id: 1076588:TBH_RS12170
uniprot id: A0A7U6GKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1076588:TBH RS00020
gene id: 1076588:TBH_RS00020
uniprot id: A0A7U6JH91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1076588:TBH RS12660
gene id: 1076588:TBH_RS12660
uniprot id: A0A7U6JIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1076588:TBH RS05935
gene id: 1076588:TBH_RS05935
uniprot id: A0A7U6JIB9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS01365
gene id: 1076588:TBH_RS01365
uniprot id: A0A7U6JGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1076588:TBH RS14720
gene id: 1076588:TBH_RS14720
uniprot id: A0A7U6GLF6
names: Similarity
messages: Belongs to the PhoH family.

1076588:TBH RS07050
gene id: 1076588:TBH_RS07050
uniprot id: A0A7U6GIN2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1076588:TBH RS01850
gene id: 1076588:TBH_RS01850
uniprot id: A0A7U6JFZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1076588:TBH RS14690
gene id: 1076588:TBH_RS14690
uniprot id: A0A7U6JIY5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1076588:TBH RS06355
gene id: 1076588:TBH_RS06355
uniprot id: A0A7U6GIC6
names: Similarity
messages: Belongs to the SufE family.

1076588:TBH RS03370
gene id: 1076588:TBH_RS03370
uniprot id: A0A7U6GH77
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1076588:TBH RS04055
gene id: 1076588:TBH_RS04055
uniprot id: A0A7U6GHK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS06235
gene id: 1076588:TBH_RS06235
uniprot id: A0A7U6JHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1076588:TBH RS12560
gene id: 1076588:TBH_RS12560
uniprot id: A0A7U6GKJ0
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS03605
gene id: 1076588:TBH_RS03605
uniprot id: A0A7U6GHB4
names: Similarity
messages: Belongs to the UPF0047 family.

1076588:TBH RS03645
gene id: 1076588:TBH_RS03645
uniprot id: A0A7U6GHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1076588:TBH RS00980
gene id: 1076588:TBH_RS00980
uniprot id: A0A7U6JHE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1076588:TBH RS05680
gene id: 1076588:TBH_RS05680
uniprot id: A0A7U6JHQ1
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS05155
gene id: 1076588:TBH_RS05155
uniprot id: A0A7U6JGW6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1076588:TBH RS00915
gene id: 1076588:TBH_RS00915
uniprot id: A0A7U6GGE1
names: Similarity
messages: Belongs to the peptidase U62 family.

1076588:TBH RS13025
gene id: 1076588:TBH_RS13025
uniprot id: A0A7U6GKN0
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02405
gene id: 1076588:TBH_RS02405
uniprot id: A0A7U6GGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1076588:TBH RS10655
gene id: 1076588:TBH_RS10655
uniprot id: A0A7U6GJU9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1076588:TBH RS10920
gene id: 1076588:TBH_RS10920
uniprot id: A0A7U6JI69
names: Subcellular Location Annotation
messages: Cytoplasm

1076588:TBH RS02725
gene id: 1076588:TBH_RS02725
uniprot id: A0A7U6GH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1076588:TBH RS07325
gene id: 1076588:TBH_RS07325
uniprot id: A0A7U6JI24
names: Similarity
messages: Belongs to the thioredoxin family.

1076588:TBH RS13320
gene id: 1076588:TBH_RS13320
uniprot id: A0A7U6JIF6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1076588:TBH RS11310
gene id: 1076588:TBH_RS11310
uniprot id: A0A7U6JJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1076588:TBH RS05285
gene id: 1076588:TBH_RS05285
uniprot id: A0A7U6GHZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1076588:TBH RS10025
gene id: 1076588:TBH_RS10025
uniprot id: A0A7U6GJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1076588:TBH RS00675
gene id: 1076588:TBH_RS00675
uniprot id: A0A7U6GGA7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1076588:TBH RS00600
gene id: 1076588:TBH_RS00600
uniprot id: A0A7U6GG92
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1076588:TBH RS07345
gene id: 1076588:TBH_RS07345
uniprot id: A0A7U6GIQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1076588:TBH RS10220
gene id: 1076588:TBH_RS10220
uniprot id: A0A7U6JHW3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1076588:TBH RS12270
gene id: 1076588:TBH_RS12270
uniprot id: A0A7U6GKI4
names: Similarity
messages: Belongs to the SfsA family.

1076588:TBH RS06640
gene id: 1076588:TBH_RS06640
uniprot id: A0A7U6GIH5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1076588:TBH RS14750
gene id: 1076588:TBH_RS14750
uniprot id: A0A7U6GLA0
names: Similarity
messages: Belongs to the RutC family.

1076588:TBH RS01180
gene id: 1076588:TBH_RS01180
uniprot id: A0A7U6GGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1076588:TBH RS15275
gene id: 1076588:TBH_RS15275
uniprot id: A0A7U6GJI1
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS06075
gene id: 1076588:TBH_RS06075
uniprot id: A0A7U6JHA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS05315
gene id: 1076588:TBH_RS05315
uniprot id: A0A7U6GHX7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1076588:TBH RS08890
gene id: 1076588:TBH_RS08890
uniprot id: A0A7U6JHM6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1076588:TBH RS01650
gene id: 1076588:TBH_RS01650
uniprot id: A0A7U6GGR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1076588:TBH RS06535
gene id: 1076588:TBH_RS06535
uniprot id: A0A7U6JHV7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1076588:TBH RS13275
gene id: 1076588:TBH_RS13275
uniprot id: A0A7U6GKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS13850
gene id: 1076588:TBH_RS13850
uniprot id: A0A7U6GKZ2
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1076588:TBH RS07685
gene id: 1076588:TBH_RS07685
uniprot id: A0A7U6JIN6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1076588:TBH RS04310
gene id: 1076588:TBH_RS04310
uniprot id: A0A7U6GHL9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1076588:TBH RS04130
gene id: 1076588:TBH_RS04130
uniprot id: A0A7U6GHK7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1076588:TBH RS06160
gene id: 1076588:TBH_RS06160
uniprot id: A0A7U6JHS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1076588:TBH RS03110
gene id: 1076588:TBH_RS03110
uniprot id: A0A7U6GH57
names: Similarity
messages: Belongs to the RelE toxin family.

1076588:TBH RS11610
gene id: 1076588:TBH_RS11610
uniprot id: A0A7U6JIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1076588:TBH RS01560
gene id: 1076588:TBH_RS01560
uniprot id: A0A7U6GGJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1076588:TBH RS00085
gene id: 1076588:TBH_RS00085
uniprot id: A0A7U6JGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1076588:TBH RS04455
gene id: 1076588:TBH_RS04455
uniprot id: A0A7U6GHN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1076588:TBH RS12470
gene id: 1076588:TBH_RS12470
uniprot id: A0A7U6GKR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS01950
gene id: 1076588:TBH_RS01950
uniprot id: A0A7U6GGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS02460
gene id: 1076588:TBH_RS02460
uniprot id: A0A7U6JH25
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1076588:TBH RS14100
gene id: 1076588:TBH_RS14100
uniprot id: A0A7U6GL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1076588:TBH RS07665
gene id: 1076588:TBH_RS07665
uniprot id: A0A7U6JI44
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1076588:TBH RS09160
gene id: 1076588:TBH_RS09160
uniprot id: A0A7U6GJC3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1076588:TBH RS04325
gene id: 1076588:TBH_RS04325
uniprot id: A0A7U6GHK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1076588:TBH RS12255
gene id: 1076588:TBH_RS12255
uniprot id: A0A7U6GKE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS04490
gene id: 1076588:TBH_RS04490
uniprot id: A0A7U6JHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1076588:TBH RS08300
gene id: 1076588:TBH_RS08300
uniprot id: A0A7U6GJ15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1076588:TBH RS08280
gene id: 1076588:TBH_RS08280
uniprot id: A0A7U6GJ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1076588:TBH RS03000
gene id: 1076588:TBH_RS03000
uniprot id: A0A7U6JHT1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1076588:TBH RS10635
gene id: 1076588:TBH_RS10635
uniprot id: A0A7U6GJW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1076588:TBH RS05845
gene id: 1076588:TBH_RS05845
uniprot id: A0A7U6JHU1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1076588:TBH RS01190
gene id: 1076588:TBH_RS01190
uniprot id: A0A7U6GGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1076588:TBH RS03235
gene id: 1076588:TBH_RS03235
uniprot id: A0A7U6JH94
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS04580
gene id: 1076588:TBH_RS04580
uniprot id: A0A7U6JHI6
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS09795
gene id: 1076588:TBH_RS09795
uniprot id: A0A7U6GJK5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1076588:TBH RS12675
gene id: 1076588:TBH_RS12675
uniprot id: A0A7U6JIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1076588:TBH RS01055
gene id: 1076588:TBH_RS01055
uniprot id: A0A7U6JGU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS13745
gene id: 1076588:TBH_RS13745
uniprot id: A0A7U6GKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS01510
gene id: 1076588:TBH_RS01510
uniprot id: A0A7U6GGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1076588:TBH RS07805
gene id: 1076588:TBH_RS07805
uniprot id: A0A7U6GIW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1076588:TBH RS13915
gene id: 1076588:TBH_RS13915
uniprot id: A0A7U6GL15
names: Similarity
messages: Belongs to the GSP E family.

1076588:TBH RS01600
gene id: 1076588:TBH_RS01600
uniprot id: A0A7U6GGK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1076588:TBH RS06360
gene id: 1076588:TBH_RS06360
uniprot id: A0A7U6GIA9
names: Similarity
messages: Belongs to the HesB/IscA family.

1076588:TBH RS08570
gene id: 1076588:TBH_RS08570
uniprot id: A0A7U6JI96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1076588:TBH RS07845
gene id: 1076588:TBH_RS07845
uniprot id: A0A7U6JI54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1076588:TBH RS05990
gene id: 1076588:TBH_RS05990
uniprot id: A0A7U6JH98
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1076588:TBH RS02055
gene id: 1076588:TBH_RS02055
uniprot id: A0A7U6GGQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS01460
gene id: 1076588:TBH_RS01460
uniprot id: A0A7U6GGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1076588:TBH RS02875
gene id: 1076588:TBH_RS02875
uniprot id: A0A7U6GH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1076588:TBH RS11000
gene id: 1076588:TBH_RS11000
uniprot id: A0A7U6JI09
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1076588:TBH RS02635
gene id: 1076588:TBH_RS02635
uniprot id: A0A7U6GGZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1076588:TBH RS11550
gene id: 1076588:TBH_RS11550
uniprot id: A0A7U6GK59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1076588:TBH RS01175
gene id: 1076588:TBH_RS01175
uniprot id: A0A7U6GGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1076588:TBH RS00710
gene id: 1076588:TBH_RS00710
uniprot id: A0A7U6GGA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1076588:TBH RS11740
gene id: 1076588:TBH_RS11740
uniprot id: A0A7U6GKB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1076588:TBH RS14290
gene id: 1076588:TBH_RS14290
uniprot id: A0A7U6GL73
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1076588:TBH RS02120
gene id: 1076588:TBH_RS02120
uniprot id: A0A7U6GGQ2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1076588:TBH RS02905
gene id: 1076588:TBH_RS02905
uniprot id: A0A7U6JGI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1076588:TBH RS09820
gene id: 1076588:TBH_RS09820
uniprot id: A0A7U6JIF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS00230
gene id: 1076588:TBH_RS00230
uniprot id: A0A7U6GG41
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1076588:TBH RS02360
gene id: 1076588:TBH_RS02360
uniprot id: A0A7U6GGU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1076588:TBH RS11800
gene id: 1076588:TBH_RS11800
uniprot id: A0A7U6GK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1076588:TBH RS01760
gene id: 1076588:TBH_RS01760
uniprot id: A0A7U6JG63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1076588:TBH RS00680
gene id: 1076588:TBH_RS00680
uniprot id: A0A7U6GG94
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1076588:TBH RS02925
gene id: 1076588:TBH_RS02925
uniprot id: A0A7U6JHS6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1076588:TBH RS01360
gene id: 1076588:TBH_RS01360
uniprot id: A0A7U6JGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1076588:TBH RS03550
gene id: 1076588:TBH_RS03550
uniprot id: A0A7U6JGI0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1076588:TBH RS00425
gene id: 1076588:TBH_RS00425
uniprot id: A0A7U6JFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1076588:TBH RS13910
gene id: 1076588:TBH_RS13910
uniprot id: A0A7U6GL98
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1076588:TBH RS06510
gene id: 1076588:TBH_RS06510
uniprot id: A0A7U6GIF6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1076588:TBH RS05650
gene id: 1076588:TBH_RS05650
uniprot id: A0A7U6GI46
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS06190
gene id: 1076588:TBH_RS06190
uniprot id: A0A7U6GIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1076588:TBH RS05050
gene id: 1076588:TBH_RS05050
uniprot id: A0A7U6GHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS10135
gene id: 1076588:TBH_RS10135
uniprot id: A0A7U6JI21
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1076588:TBH RS14755
gene id: 1076588:TBH_RS14755
uniprot id: A0A7U6GLF1
names: Similarity
messages: Belongs to the UPF0047 family.

1076588:TBH RS01465
gene id: 1076588:TBH_RS01465
uniprot id: A0A7U6GGM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1076588:TBH RS02900
gene id: 1076588:TBH_RS02900
uniprot id: A0A7U6GH15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1076588:TBH RS08135
gene id: 1076588:TBH_RS08135
uniprot id: A0A7U6GJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1076588:TBH RS14225
gene id: 1076588:TBH_RS14225
uniprot id: A0A7U6JJJ7
names: Similarity
messages: Belongs to the FPG family.

1076588:TBH RS01290
gene id: 1076588:TBH_RS01290
uniprot id: A0A7U6JFT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS01245
gene id: 1076588:TBH_RS01245
uniprot id: A0A7U6GGH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1076588:TBH RS07015
gene id: 1076588:TBH_RS07015
uniprot id: A0A7U6JI07
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1076588:TBH RS14820
gene id: 1076588:TBH_RS14820
uniprot id: A0A7U6GLN6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1076588:TBH RS13380
gene id: 1076588:TBH_RS13380
uniprot id: A0A7U6JIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1076588:TBH RS13410
gene id: 1076588:TBH_RS13410
uniprot id: A0A7U6GKZ0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1076588:TBH RS11030
gene id: 1076588:TBH_RS11030
uniprot id: A0A7U6GJZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS01070
gene id: 1076588:TBH_RS01070
uniprot id: A0A7U6GGE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS03390
gene id: 1076588:TBH_RS03390
uniprot id: A0A7U6JHA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1076588:TBH RS05425
gene id: 1076588:TBH_RS05425
uniprot id: A0A7U6GHZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1076588:TBH RS02870
gene id: 1076588:TBH_RS02870
uniprot id: A0A7U6GH71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1076588:TBH RS01015
gene id: 1076588:TBH_RS01015
uniprot id: A0A7U6GGB6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1076588:TBH RS04295
gene id: 1076588:TBH_RS04295
uniprot id: A0A7U6GHM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1076588:TBH RS01680
gene id: 1076588:TBH_RS01680
uniprot id: A0A7U6GGK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1076588:TBH RS07880
gene id: 1076588:TBH_RS07880
uniprot id: A0A7U6GIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1076588:TBH RS05555
gene id: 1076588:TBH_RS05555
uniprot id: A0A7U6GI48
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1076588:TBH RS07885
gene id: 1076588:TBH_RS07885
uniprot id: A0A7U6GIT2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1076588:TBH RS09350
gene id: 1076588:TBH_RS09350
uniprot id: A0A7U6JHV9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1076588:TBH RS01075
gene id: 1076588:TBH_RS01075
uniprot id: A0A7U6GGE8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS09065
gene id: 1076588:TBH_RS09065
uniprot id: A0A7U6GJC6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1076588:TBH RS07930
gene id: 1076588:TBH_RS07930
uniprot id: A0A7U6JHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1076588:TBH RS01610
gene id: 1076588:TBH_RS01610
uniprot id: A0A7U6JG43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1076588:TBH RS10170
gene id: 1076588:TBH_RS10170
uniprot id: A0A7U6GJR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1076588:TBH RS09940
gene id: 1076588:TBH_RS09940
uniprot id: A0A7U6GJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1076588:TBH RS12890
gene id: 1076588:TBH_RS12890
uniprot id: A0A7U6GKN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1076588:TBH RS02315
gene id: 1076588:TBH_RS02315
uniprot id: A0A7U6GGU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1076588:TBH RS11805
gene id: 1076588:TBH_RS11805
uniprot id: A0A7U6GKC2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1076588:TBH RS04790
gene id: 1076588:TBH_RS04790
uniprot id: A0A7U6GHR7
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1076588:TBH RS02210
gene id: 1076588:TBH_RS02210
uniprot id: A0A7U6JGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1076588:TBH RS13400
gene id: 1076588:TBH_RS13400
uniprot id: A0A7U6JKY3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1076588:TBH RS11640
gene id: 1076588:TBH_RS11640
uniprot id: A0A7U6GK67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS00090
gene id: 1076588:TBH_RS00090
uniprot id: A0A7U6JFG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1076588:TBH RS13795
gene id: 1076588:TBH_RS13795
uniprot id: A0A7U6JIR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1076588:TBH RS15485
gene id: 1076588:TBH_RS15485
uniprot id: A0A7U6GLB9
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1076588:TBH RS10565
gene id: 1076588:TBH_RS10565
uniprot id: A0A7U6GJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1076588:TBH RS03985
gene id: 1076588:TBH_RS03985
uniprot id: A0A7U6GHJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1076588:TBH RS07150
gene id: 1076588:TBH_RS07150
uniprot id: A0A7U6GIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1076588:TBH RS12025
gene id: 1076588:TBH_RS12025
uniprot id: A0A7U6GKC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1076588:TBH RS01210
gene id: 1076588:TBH_RS01210
uniprot id: A0A7U6JFT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1076588:TBH RS10180
gene id: 1076588:TBH_RS10180
uniprot id: A0A7U6GJN3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1076588:TBH RS13265
gene id: 1076588:TBH_RS13265
uniprot id: A0A7U6GKR1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1076588:TBH RS05860
gene id: 1076588:TBH_RS05860
uniprot id: A0A7U6GI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1076588:TBH RS11075
gene id: 1076588:TBH_RS11075
uniprot id: A0A7U6JI14
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1076588:TBH RS01215
gene id: 1076588:TBH_RS01215
uniprot id: A0A7U6JHF9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS08870
gene id: 1076588:TBH_RS08870
uniprot id: A0A7U6GJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1076588:TBH RS03585
gene id: 1076588:TBH_RS03585
uniprot id: A0A7U6GHB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1076588:TBH RS05835
gene id: 1076588:TBH_RS05835
uniprot id: A0A7U6JH88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS04975
gene id: 1076588:TBH_RS04975
uniprot id: A0A7U6GHR6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1076588:TBH RS06755
gene id: 1076588:TBH_RS06755
uniprot id: A0A7U6JHF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1076588:TBH RS00790
gene id: 1076588:TBH_RS00790
uniprot id: A0A7U6GGB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1076588:TBH RS11730
gene id: 1076588:TBH_RS11730
uniprot id: A0A7U6GKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1076588:TBH RS01605
gene id: 1076588:TBH_RS01605
uniprot id: A0A7U6GGJ5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1076588:TBH RS12535
gene id: 1076588:TBH_RS12535
uniprot id: A0A7U6GKI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1076588:TBH RS09900
gene id: 1076588:TBH_RS09900
uniprot id: A0A7U6GH90
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS05955
gene id: 1076588:TBH_RS05955
uniprot id: A0A7U6GI75
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS07545
gene id: 1076588:TBH_RS07545
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS06310
gene id: 1076588:TBH_RS06310
uniprot id: A0A7U6JHC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1076588:TBH RS11755
gene id: 1076588:TBH_RS11755
uniprot id: A0A7U6JIW0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1076588:TBH RS11735
gene id: 1076588:TBH_RS11735
uniprot id: A0A7U6GKC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1076588:TBH RS09390
gene id: 1076588:TBH_RS09390
uniprot id: A0A7U6GJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1076588:TBH RS07355
gene id: 1076588:TBH_RS07355
uniprot id: A0A7U6GIQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1076588:TBH RS03650
gene id: 1076588:TBH_RS03650
uniprot id: A0A7U6GHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1076588:TBH RS14515
gene id: 1076588:TBH_RS14515
uniprot id: A0A7U6GL86
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1076588:TBH RS08635
gene id: 1076588:TBH_RS08635
uniprot id: A0A7U6JHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1076588:TBH RS02860
gene id: 1076588:TBH_RS02860
uniprot id: A0A7U6GH22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1076588:TBH RS04365
gene id: 1076588:TBH_RS04365
uniprot id: A0A7U6GHM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS07960
gene id: 1076588:TBH_RS07960
uniprot id: A0A7U6GIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1076588:TBH RS10085
gene id: 1076588:TBH_RS10085
uniprot id: A0A7U6GJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1076588:TBH RS07000
gene id: 1076588:TBH_RS07000
uniprot id: A0A7U6GIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1076588:TBH RS03460
gene id: 1076588:TBH_RS03460
uniprot id: A0A7U6JGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1076588:TBH RS06935
gene id: 1076588:TBH_RS06935
uniprot id: A0A7U6JI03
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS11565
gene id: 1076588:TBH_RS11565
uniprot id: A0A7U6GKC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1076588:TBH RS00660
gene id: 1076588:TBH_RS00660
uniprot id: A0A7U6JGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1076588:TBH RS12265
gene id: 1076588:TBH_RS12265
uniprot id: A0A7U6GKI7
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1076588:TBH RS11110
gene id: 1076588:TBH_RS11110
uniprot id: A0A7U6GK00
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1076588:TBH RS05940
gene id: 1076588:TBH_RS05940
uniprot id: A0A7U6GI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1076588:TBH RS07300
gene id: 1076588:TBH_RS07300
uniprot id: A0A7U6GIL5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1076588:TBH RS05560
gene id: 1076588:TBH_RS05560
uniprot id: A0A7U6GI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1076588:TBH RS09045
gene id: 1076588:TBH_RS09045
uniprot id: A0A7U6JIY6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1076588:TBH RS13845
gene id: 1076588:TBH_RS13845
uniprot id: A0A7U6GL07
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1076588:TBH RS06970
gene id: 1076588:TBH_RS06970
uniprot id: A0A7U6GIK2
names: Similarity
messages: Belongs to the MotB family.

1076588:TBH RS10605
gene id: 1076588:TBH_RS10605
uniprot id: A0A7U6JIK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS02020
gene id: 1076588:TBH_RS02020
uniprot id: A0A7U6GGU3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1076588:TBH RS13200
gene id: 1076588:TBH_RS13200
uniprot id: A0A7U6GKS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS13625
gene id: 1076588:TBH_RS13625
uniprot id: A0A7U6JJI0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1076588:TBH RS03780
gene id: 1076588:TBH_RS03780
uniprot id: A0A7U6JHD1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1076588:TBH RS11045
gene id: 1076588:TBH_RS11045
uniprot id: A0A7U6GJW2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS07720
gene id: 1076588:TBH_RS07720
uniprot id: A0A7U6GIV1
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1076588:TBH RS02970
gene id: 1076588:TBH_RS02970
uniprot id: A0A7U6GH29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1076588:TBH RS11585
gene id: 1076588:TBH_RS11585
uniprot id: A0A7U6GK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1076588:TBH RS15345
gene id: 1076588:TBH_RS15345
uniprot id: A0A7U6GKH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1076588:TBH RS08575
gene id: 1076588:TBH_RS08575
uniprot id: A0A7U6JHK6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1076588:TBH RS00205
gene id: 1076588:TBH_RS00205
uniprot id: A0A7U6GG43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1076588:TBH RS02050
gene id: 1076588:TBH_RS02050
uniprot id: A0A7U6GGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1076588:TBH RS00415
gene id: 1076588:TBH_RS00415
uniprot id: A0A7U6JGL4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1076588:TBH RS02250
gene id: 1076588:TBH_RS02250
uniprot id: A0A7U6GGZ1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1076588:TBH RS05585
gene id: 1076588:TBH_RS05585
uniprot id: A0A7U6GI02
names: Similarity
messages: Belongs to the HesB/IscA family.

1076588:TBH RS00645
gene id: 1076588:TBH_RS00645
uniprot id: A0A7U6GG90
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1076588:TBH RS12705
gene id: 1076588:TBH_RS12705
uniprot id: A0A7U6GKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1076588:TBH RS07395
gene id: 1076588:TBH_RS07395
uniprot id: A0A7U6JHI4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1076588:TBH RS05260
gene id: 1076588:TBH_RS05260
uniprot id: A0A7U6GHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1076588:TBH RS10155
gene id: 1076588:TBH_RS10155
uniprot id: A0A7U6JJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS14650
gene id: 1076588:TBH_RS14650
uniprot id: A0A7U6GL93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1076588:TBH RS03185
gene id: 1076588:TBH_RS03185
uniprot id: A0A7U6GH68
names: Subcellular Location Annotation
messages: Periplasm

1076588:TBH RS02975
gene id: 1076588:TBH_RS02975
uniprot id: A0A7U6GH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1076588:TBH RS09445
gene id: 1076588:TBH_RS09445
uniprot id: A0A7U6JHR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1076588:TBH RS04660
gene id: 1076588:TBH_RS04660
uniprot id: A0A7U6JHI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1076588:TBH RS05195
gene id: 1076588:TBH_RS05195
uniprot id: A0A7U6GHX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1076588:TBH RS04220
gene id: 1076588:TBH_RS04220
uniprot id: A0A7U6GHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1076588:TBH RS09800
gene id: 1076588:TBH_RS09800
uniprot id: A0A7U6GJE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS00530
gene id: 1076588:TBH_RS00530
uniprot id: A0A7U6GG86
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1076588:TBH RS12930
gene id: 1076588:TBH_RS12930
uniprot id: A0A7U6JKK7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1076588:TBH RS08030
gene id: 1076588:TBH_RS08030
uniprot id: A0A7U6GJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1076588:TBH RS09540
gene id: 1076588:TBH_RS09540
uniprot id: A0A7U6GJJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1076588:TBH RS13665
gene id: 1076588:TBH_RS13665
uniprot id: A0A7U6GKX2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1076588:TBH RS06865
gene id: 1076588:TBH_RS06865
uniprot id: A0A7U6GIJ2
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1076588:TBH RS11745
gene id: 1076588:TBH_RS11745
uniprot id: A0A7U6JID2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1076588:TBH RS01590
gene id: 1076588:TBH_RS01590
uniprot id: A0A7U6GGJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1076588:TBH RS10090
gene id: 1076588:TBH_RS10090
uniprot id: A0A7U6GJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1076588:TBH RS05945
gene id: 1076588:TBH_RS05945
uniprot id: A0A7U6GI81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1076588:TBH RS10300
gene id: 1076588:TBH_RS10300
uniprot id: A0A7U6JJD6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1076588:TBH RS00325
gene id: 1076588:TBH_RS00325
uniprot id: A0A7U6GG46
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1076588:TBH RS13525
gene id: 1076588:TBH_RS13525
uniprot id: A0A7U6GKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1076588:TBH RS02150
gene id: 1076588:TBH_RS02150
uniprot id: A0A7U6JG33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1076588:TBH RS09805
gene id: 1076588:TBH_RS09805
uniprot id: A0A7U6GJK8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1076588:TBH RS00010
gene id: 1076588:TBH_RS00010
uniprot id: A0A7U6JGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1076588:TBH RS05870
gene id: 1076588:TBH_RS05870
uniprot id: A0A7U6GI83
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS11665
gene id: 1076588:TBH_RS11665
uniprot id: A0A7U6GK95
names: Similarity
messages: Belongs to the peptidase S41A family.

1076588:TBH RS06600
gene id: 1076588:TBH_RS06600
uniprot id: A0A7U6GIG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS04140
gene id: 1076588:TBH_RS04140
uniprot id: A0A7U6GHI5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1076588:TBH RS11035
gene id: 1076588:TBH_RS11035
uniprot id: A0A7U6GJZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1076588:TBH RS01285
gene id: 1076588:TBH_RS01285
uniprot id: A0A7U6JGX0
names: Similarity
messages: Belongs to the thioredoxin family.

1076588:TBH RS06660
gene id: 1076588:TBH_RS06660
uniprot id: A0A7U6GIH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1076588:TBH RS01685
gene id: 1076588:TBH_RS01685
uniprot id: A0A7U6JG50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1076588:TBH RS05245
gene id: 1076588:TBH_RS05245
uniprot id: A0A7U6GHY8
names: Similarity
messages: Belongs to the UPF0758 family.

1076588:TBH RS13430
gene id: 1076588:TBH_RS13430
uniprot id: A0A7U6GKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1076588:TBH RS04440
gene id: 1076588:TBH_RS04440
uniprot id: A0A7U6GHN1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1076588:TBH RS15085
gene id: 1076588:TBH_RS15085
uniprot id: A0A7U6JGF3
names: Similarity
messages: Belongs to the isochorismate synthase family.

1076588:TBH RS12480
gene id: 1076588:TBH_RS12480
uniprot id: A0A7U6GKH6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1076588:TBH RS14530
gene id: 1076588:TBH_RS14530
uniprot id: A0A7U6GL96
names: Subcellular Location Annotation
messages: Cell inner membrane

1076588:TBH RS08515
gene id: 1076588:TBH_RS08515
uniprot id: A0A7U6GJ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1076588:TBH RS12490
gene id: 1076588:TBH_RS12490
uniprot id: A0A7U6GKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1076588:TBH RS00260
gene id: 1076588:TBH_RS00260
uniprot id: A0A7U6JFQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS13325
gene id: 1076588:TBH_RS13325
uniprot id: A0A7U6JKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1076588:TBH RS12595
gene id: 1076588:TBH_RS12595
uniprot id: A0A7U6JJ51
names: Similarity
messages: Belongs to the peptidase M1 family.

1076588:TBH RS10140
gene id: 1076588:TBH_RS10140
uniprot id: A0A7U6JIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS05565
gene id: 1076588:TBH_RS05565
uniprot id: A0A7U6GI15
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1076588:TBH RS00460
gene id: 1076588:TBH_RS00460
uniprot id: A0A7U6GG70
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1076588:TBH RS01620
gene id: 1076588:TBH_RS01620
uniprot id: A0A7U6JGZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1076588:TBH RS04605
gene id: 1076588:TBH_RS04605
uniprot id: A0A7U6GHQ8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1076588:TBH RS13290
gene id: 1076588:TBH_RS13290
uniprot id: A0A7U6GKY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS02990
gene id: 1076588:TBH_RS02990
uniprot id: A0A7U6JHB5
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS14805
gene id: 1076588:TBH_RS14805
uniprot id: A0A7U6GLB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1076588:TBH RS01695
gene id: 1076588:TBH_RS01695
uniprot id: A0A7U6JGZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1076588:TBH RS00350
gene id: 1076588:TBH_RS00350
uniprot id: A0A7U6JFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1076588:TBH RS08730
gene id: 1076588:TBH_RS08730
uniprot id: A0A7U6JHL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS02260
gene id: 1076588:TBH_RS02260
uniprot id: A0A7U6GGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1076588:TBH RS06140
gene id: 1076588:TBH_RS06140
uniprot id: A0A7U6GI76
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

1076588:TBH RS01435
gene id: 1076588:TBH_RS01435
uniprot id: A0A7U6JGU0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1076588:TBH RS13130
gene id: 1076588:TBH_RS13130
uniprot id: A0A7U6GKQ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1076588:TBH RS03975
gene id: 1076588:TBH_RS03975
uniprot id: A0A7U6GHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS08545
gene id: 1076588:TBH_RS08545
uniprot id: A0A7U6GIZ8
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1076588:TBH RS00040
gene id: 1076588:TBH_RS00040
uniprot id: A0A7U6GG24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1076588:TBH RS00605
gene id: 1076588:TBH_RS00605
uniprot id: A0A7U6GG81
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1076588:TBH RS08340
gene id: 1076588:TBH_RS08340
uniprot id: A0A7U6JI70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1076588:TBH RS06695
gene id: 1076588:TBH_RS06695
uniprot id: A0A7U6JH92
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1076588:TBH RS12550
gene id: 1076588:TBH_RS12550
uniprot id: A0A7U6GKS9
names: Subcellular Location Annotation
messages: Cell inner membrane

1076588:TBH RS08335
gene id: 1076588:TBH_RS08335
uniprot id: A0A7U6JHN9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1076588:TBH RS09385
gene id: 1076588:TBH_RS09385
uniprot id: A0A7U6GJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1076588:TBH RS12445
gene id: 1076588:TBH_RS12445
uniprot id: A0A7U6JIA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS07180
gene id: 1076588:TBH_RS07180
uniprot id: A0A7U6JIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1076588:TBH RS10895
gene id: 1076588:TBH_RS10895
uniprot id: A0A7U6GJW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS11420
gene id: 1076588:TBH_RS11420
uniprot id: A0A7U6GK22
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1076588:TBH RS01380
gene id: 1076588:TBH_RS01380
uniprot id: A0A7U6GGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1076588:TBH RS06705
gene id: 1076588:TBH_RS06705
uniprot id: A0A7U6GIF3
names: Similarity
messages: Belongs to the UPF0166 family.

1076588:TBH RS01975
gene id: 1076588:TBH_RS01975
uniprot id: A0A7U6GGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1076588:TBH RS11590
gene id: 1076588:TBH_RS11590
uniprot id: A0A7U6GKA3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1076588:TBH RS07375
gene id: 1076588:TBH_RS07375
uniprot id: A0A7U6GIR0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1076588:TBH RS03200
gene id: 1076588:TBH_RS03200
uniprot id: A0A7U6GH73
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1076588:TBH RS11600
gene id: 1076588:TBH_RS11600
uniprot id: A0A7U6JIC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1076588:TBH RS06745
gene id: 1076588:TBH_RS06745
uniprot id: A0A7U6GIG0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1076588:TBH RS11505
gene id: 1076588:TBH_RS11505
uniprot id: A0A7U6GK92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1076588:TBH RS08580
gene id: 1076588:TBH_RS08580
uniprot id: A0A7U6JIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1076588:TBH RS13755
gene id: 1076588:TBH_RS13755
uniprot id: A0A7U6GKX7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1076588:TBH RS05230
gene id: 1076588:TBH_RS05230
uniprot id: A0A7U6JGX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1076588:TBH RS10610
gene id: 1076588:TBH_RS10610
uniprot id: A0A7U6JIM3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1076588:TBH RS14630
gene id: 1076588:TBH_RS14630
uniprot id: A0A7U6JIN8
names: Similarity
messages: Belongs to the peptidase S33 family.

1076588:TBH RS10460
gene id: 1076588:TBH_RS10460
uniprot id: A0A7U6JIL5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS00780
gene id: 1076588:TBH_RS00780
uniprot id: A0A7U6GGC0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS06260
gene id: 1076588:TBH_RS06260
uniprot id: A0A7U6GI92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS01795
gene id: 1076588:TBH_RS01795
uniprot id: A0A7U6GGQ6
names: Similarity
messages: Belongs to the peptidase S41A family.

1076588:TBH RS12845
gene id: 1076588:TBH_RS12845
uniprot id: A0A7U6JKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1076588:TBH RS05450
gene id: 1076588:TBH_RS05450
uniprot id: A0A7U6JHR9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS04620
gene id: 1076588:TBH_RS04620
uniprot id: A0A7U6GHQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1076588:TBH RS07815
gene id: 1076588:TBH_RS07815
uniprot id: A0A7U6GIV6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1076588:TBH RS11375
gene id: 1076588:TBH_RS11375
uniprot id: A0A7U6JIS8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1076588:TBH RS01765
gene id: 1076588:TBH_RS01765
uniprot id: A0A7U6JGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1076588:TBH RS06810
gene id: 1076588:TBH_RS06810
uniprot id: A0A7U6GIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS01710
gene id: 1076588:TBH_RS01710
uniprot id: A0A7U6GGL6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1076588:TBH RS04305
gene id: 1076588:TBH_RS04305
uniprot id: A0A7U6GHJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1076588:TBH RS05610
gene id: 1076588:TBH_RS05610
uniprot id: A0A7U6JGZ8
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02090
gene id: 1076588:TBH_RS02090
uniprot id: A0A7U6GGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1076588:TBH RS12220
gene id: 1076588:TBH_RS12220
uniprot id: A0A7U6JK85
names: Similarity
messages: Belongs to the UPF0276 family.

1076588:TBH RS00705
gene id: 1076588:TBH_RS00705
uniprot id: A0A7U6GG83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1076588:TBH RS05390
gene id: 1076588:TBH_RS05390
uniprot id: A0A7U6JGX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1076588:TBH RS03385
gene id: 1076588:TBH_RS03385
uniprot id: A0A7U6JGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1076588:TBH RS08440
gene id: 1076588:TBH_RS08440
uniprot id: A0A7U6GJ46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1076588:TBH RS10575
gene id: 1076588:TBH_RS10575
uniprot id: A0A7U6GJR4
names: Similarity
messages: Belongs to the peptidase M16 family.

1076588:TBH RS00700
gene id: 1076588:TBH_RS00700
uniprot id: A0A7U6GGA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1076588:TBH RS12655
gene id: 1076588:TBH_RS12655
uniprot id: A0A7U6GKN6
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS00440
gene id: 1076588:TBH_RS00440
uniprot id: A0A7U6GG58
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1076588:TBH RS11360
gene id: 1076588:TBH_RS11360
uniprot id: A0A7U6GK63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1076588:TBH RS13470
gene id: 1076588:TBH_RS13470
uniprot id: A0A7U6JIG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1076588:TBH RS03790
gene id: 1076588:TBH_RS03790
uniprot id: A0A7U6JGK8
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS10615
gene id: 1076588:TBH_RS10615
uniprot id: A0A7U6JHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1076588:TBH RS15120
gene id: 1076588:TBH_RS15120
uniprot id: A0A7U6GHN9
names: Similarity
messages: Belongs to the peptidase S8 family.

1076588:TBH RS12795
gene id: 1076588:TBH_RS12795
uniprot id: A0A7U6GKL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1076588:TBH RS02000
gene id: 1076588:TBH_RS02000
uniprot id: A0A7U6JG12
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1076588:TBH RS12285
gene id: 1076588:TBH_RS12285
uniprot id: A0A7U6JJ10
names: Similarity
messages: Belongs to the acylphosphatase family.

1076588:TBH RS06005
gene id: 1076588:TBH_RS06005
uniprot id: A0A7U6JH28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1076588:TBH RS08860
gene id: 1076588:TBH_RS08860
uniprot id: A0A7U6GJ35
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1076588:TBH RS07620
gene id: 1076588:TBH_RS07620
uniprot id: A0A7U6GIU1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1076588:TBH RS05045
gene id: 1076588:TBH_RS05045
uniprot id: A0A7U6GHW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1076588:TBH RS11515
gene id: 1076588:TBH_RS11515
uniprot id: A0A7U6JIB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1076588:TBH RS06635
gene id: 1076588:TBH_RS06635
uniprot id: A0A7U6GIG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1076588:TBH RS13505
gene id: 1076588:TBH_RS13505
uniprot id: A0A7U6GKV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1076588:TBH RS00005
gene id: 1076588:TBH_RS00005
uniprot id: A0A7U6JGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1076588:TBH RS00875
gene id: 1076588:TBH_RS00875
uniprot id: A0A7U6GGB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS07070
gene id: 1076588:TBH_RS07070
uniprot id: A0A7U6GIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1076588:TBH RS08350
gene id: 1076588:TBH_RS08350
uniprot id: A0A7U6JHJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1076588:TBH RS08905
gene id: 1076588:TBH_RS08905
uniprot id: A0A7U6GJA5
names: Similarity
messages: Belongs to the thioredoxin family.

1076588:TBH RS12630
gene id: 1076588:TBH_RS12630
uniprot id: A0A7U6GKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1076588:TBH RS01335
gene id: 1076588:TBH_RS01335
uniprot id: A0A7U6GGF8
names: Similarity
messages: Belongs to the UPF0250 family.

1076588:TBH RS11240
gene id: 1076588:TBH_RS11240
uniprot id: A0A7U6JJP6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1076588:TBH RS00225
gene id: 1076588:TBH_RS00225
uniprot id: A0A7U6GG47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS12330
gene id: 1076588:TBH_RS12330
uniprot id: A0A7U6GKF1
names: Similarity
messages: Belongs to the ArsC family.

1076588:TBH RS12950
gene id: 1076588:TBH_RS12950
uniprot id: A0A7U6GKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS11780
gene id: 1076588:TBH_RS11780
uniprot id: A0A7U6GK89
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1076588:TBH RS00730
gene id: 1076588:TBH_RS00730
uniprot id: A0A7U6JGN6
names: Similarity
messages: Belongs to the peptidase M24B family.

1076588:TBH RS08940
gene id: 1076588:TBH_RS08940
uniprot id: A0A7U6GJ98
names: Similarity
messages: Belongs to the MEMO1 family.

1076588:TBH RS07030
gene id: 1076588:TBH_RS07030
uniprot id: A0A7U6GII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1076588:TBH RS02425
gene id: 1076588:TBH_RS02425
uniprot id: A0A7U6GGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1076588:TBH RS04045
gene id: 1076588:TBH_RS04045
uniprot id: A0A7U6GHH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1076588:TBH RS05400
gene id: 1076588:TBH_RS05400
uniprot id: A0A7U6GHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1076588:TBH RS03710
gene id: 1076588:TBH_RS03710
uniprot id: A0A7U6JHX7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1076588:TBH RS11025
gene id: 1076588:TBH_RS11025
uniprot id: A0A7U6GK53
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1076588:TBH RS01755
gene id: 1076588:TBH_RS01755
uniprot id: A0A7U6GGL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1076588:TBH RS00870
gene id: 1076588:TBH_RS00870
uniprot id: A0A7U6GGB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS05705
gene id: 1076588:TBH_RS05705
uniprot id: A0A7U6GI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1076588:TBH RS09085
gene id: 1076588:TBH_RS09085
uniprot id: A0A7U6GJ67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1076588:TBH RS13885
gene id: 1076588:TBH_RS13885
uniprot id: A0A7U6JIJ1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1076588:TBH RS07790
gene id: 1076588:TBH_RS07790
uniprot id: A0A7U6GIW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1076588:TBH RS01655
gene id: 1076588:TBH_RS01655
uniprot id: A0A7U6GGP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1076588:TBH RS12185
gene id: 1076588:TBH_RS12185
uniprot id: A0A7U6GKI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS01540
gene id: 1076588:TBH_RS01540
uniprot id: A0A7U6JGU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1076588:TBH RS14895
gene id: 1076588:TBH_RS14895
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS00830
gene id: 1076588:TBH_RS00830
uniprot id: A0A7U6GGC2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1076588:TBH RS07840
gene id: 1076588:TBH_RS07840
uniprot id: A0A7U6JI38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS06270
gene id: 1076588:TBH_RS06270
uniprot id: A0A7U6GID3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1076588:TBH RS13765
gene id: 1076588:TBH_RS13765
uniprot id: A0A7U6GKZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1076588:TBH RS10865
gene id: 1076588:TBH_RS10865
uniprot id: A0A7U6JJK1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1076588:TBH RS07910
gene id: 1076588:TBH_RS07910
uniprot id: A0A7U6GIZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1076588:TBH RS03070
gene id: 1076588:TBH_RS03070
uniprot id: A0A7U6JH82
names: Similarity
messages: Belongs to the transposase 8 family.

1076588:TBH RS14215
gene id: 1076588:TBH_RS14215
uniprot id: A0A7U6GL67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1076588:TBH RS04205
gene id: 1076588:TBH_RS04205
uniprot id: A0A7U6GHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1076588:TBH RS13595
gene id: 1076588:TBH_RS13595
uniprot id: A0A7U6GL18
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1076588:TBH RS06760
gene id: 1076588:TBH_RS06760
uniprot id: A0A7U6JHX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1076588:TBH RS14510
gene id: 1076588:TBH_RS14510
uniprot id: A0A7U6GL84
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1076588:TBH RS10165
gene id: 1076588:TBH_RS10165
uniprot id: A0A7U6GJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS08955
gene id: 1076588:TBH_RS08955
uniprot id: A0A7U6JIA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1076588:TBH RS02855
gene id: 1076588:TBH_RS02855
uniprot id: A0A7U6GH11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1076588:TBH RS12125
gene id: 1076588:TBH_RS12125
uniprot id: A0A7U6JIF8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1076588:TBH RS00360
gene id: 1076588:TBH_RS00360
uniprot id: A0A7U6GG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1076588:TBH RS03690
gene id: 1076588:TBH_RS03690
uniprot id: A0A7U6JGQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1076588:TBH RS07835
gene id: 1076588:TBH_RS07835
uniprot id: A0A7U6JHK7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1076588:TBH RS05820
gene id: 1076588:TBH_RS05820
uniprot id: A0A7U6GI33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1076588:TBH RS01820
gene id: 1076588:TBH_RS01820
uniprot id: A0A7U6GGM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1076588:TBH RS04060
gene id: 1076588:TBH_RS04060
uniprot id: A0A7U6GHJ9
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS06730
gene id: 1076588:TBH_RS06730
uniprot id: A0A7U6GIG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS09180
gene id: 1076588:TBH_RS09180
uniprot id: A0A7U6GJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS10150
gene id: 1076588:TBH_RS10150
uniprot id: A0A7U6JHV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS04585
gene id: 1076588:TBH_RS04585
uniprot id: A0A7U6JHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS01145
gene id: 1076588:TBH_RS01145
uniprot id: A0A7U6GGF6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1076588:TBH RS01595
gene id: 1076588:TBH_RS01595
uniprot id: A0A7U6GGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1076588:TBH RS04330
gene id: 1076588:TBH_RS04330
uniprot id: A0A7U6JGW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1076588:TBH RS03640
gene id: 1076588:TBH_RS03640
uniprot id: A0A7U6GHD4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1076588:TBH RS14020
gene id: 1076588:TBH_RS14020
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS05505
gene id: 1076588:TBH_RS05505
uniprot id: A0A7U6GHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1076588:TBH RS11885
gene id: 1076588:TBH_RS11885
uniprot id: A0A7U6GKD9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1076588:TBH RS08835
gene id: 1076588:TBH_RS08835
uniprot id: A0A7U6GJB4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1076588:TBH RS11580
gene id: 1076588:TBH_RS11580
uniprot id: A0A7U6GK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1076588:TBH RS03425
gene id: 1076588:TBH_RS03425
uniprot id: A0A7U6GHC1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1076588:TBH RS06295
gene id: 1076588:TBH_RS06295
uniprot id: A0A7U6GI93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS05420
gene id: 1076588:TBH_RS05420
uniprot id: A0A7U6GI11
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1076588:TBH RS01815
gene id: 1076588:TBH_RS01815
uniprot id: A0A7U6GGL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1076588:TBH RS04785
gene id: 1076588:TBH_RS04785
uniprot id: A0A7U6GHT3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1076588:TBH RS05965
gene id: 1076588:TBH_RS05965
uniprot id: A0A7U6GI60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1076588:TBH RS14740
gene id: 1076588:TBH_RS14740
uniprot id: A0A7U6GLB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1076588:TBH RS08910
gene id: 1076588:TBH_RS08910
uniprot id: A0A7U6GJC8
names: Similarity
messages: Belongs to the thioredoxin family.

1076588:TBH RS13935
gene id: 1076588:TBH_RS13935
uniprot id: A0A7U6GL34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1076588:TBH RS08840
gene id: 1076588:TBH_RS08840
uniprot id: A0A7U6GJ96
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1076588:TBH RS07410
gene id: 1076588:TBH_RS07410
uniprot id: A0A7U6JHD3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1076588:TBH RS02755
gene id: 1076588:TBH_RS02755
uniprot id: A0A7U6JGG9
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS04335
gene id: 1076588:TBH_RS04335
uniprot id: A0A7U6JHH0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1076588:TBH RS13310
gene id: 1076588:TBH_RS13310
uniprot id: A0A7U6JJ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1076588:TBH RS03280
gene id: 1076588:TBH_RS03280
uniprot id: A0A7U6GH80
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1076588:TBH RS10175
gene id: 1076588:TBH_RS10175
uniprot id: A0A7U6GJS8
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS10840
gene id: 1076588:TBH_RS10840
uniprot id: A0A7U6GJZ9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1076588:TBH RS09135
gene id: 1076588:TBH_RS09135
uniprot id: A0A7U6GJD8
names: Similarity
messages: Belongs to the XFP family.

1076588:TBH RS14340
gene id: 1076588:TBH_RS14340
uniprot id: A0A7U6GLE2
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1076588:TBH RS09145
gene id: 1076588:TBH_RS09145
uniprot id: A0A7U6GJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS09060
gene id: 1076588:TBH_RS09060
uniprot id: A0A7U6GJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1076588:TBH RS01660
gene id: 1076588:TBH_RS01660
uniprot id: A0A7U6GGM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1076588:TBH RS04495
gene id: 1076588:TBH_RS04495
uniprot id: A0A7U6JHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1076588:TBH RS09600
gene id: 1076588:TBH_RS09600
uniprot id: A0A7U6JHS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1076588:TBH RS10675
gene id: 1076588:TBH_RS10675
uniprot id: A0A7U6JI56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1076588:TBH RS04405
gene id: 1076588:TBH_RS04405
uniprot id: A0A7U6GHM2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1076588:TBH RS10915
gene id: 1076588:TBH_RS10915
uniprot id: A0A7U6GK11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1076588:TBH RS13315
gene id: 1076588:TBH_RS13315
uniprot id: A0A7U6JJE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1076588:TBH RS08685
gene id: 1076588:TBH_RS08685
uniprot id: A0A7U6GJ57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1076588:TBH RS05015
gene id: 1076588:TBH_RS05015
uniprot id: A0A7U6GHV8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1076588:TBH RS13810
gene id: 1076588:TBH_RS13810
uniprot id: A0A7U6JII8
names: Similarity
messages: Belongs to the HesB/IscA family.

1076588:TBH RS13385
gene id: 1076588:TBH_RS13385
uniprot id: A0A7U6JJ93
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1076588:TBH RS11765
gene id: 1076588:TBH_RS11765
uniprot id: A0A7U6JJY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1076588:TBH RS06985
gene id: 1076588:TBH_RS06985
uniprot id: A0A7U6GIL7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1076588:TBH RS07280
gene id: 1076588:TBH_RS07280
uniprot id: A0A7U6GIP7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1076588:TBH RS00725
gene id: 1076588:TBH_RS00725
uniprot id: A0A7U6JFU6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1076588:TBH RS14725
gene id: 1076588:TBH_RS14725
uniprot id: A0A7U6GLA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1076588:TBH RS02920
gene id: 1076588:TBH_RS02920
uniprot id: A0A7U6JGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1076588:TBH RS14440
gene id: 1076588:TBH_RS14440
uniprot id: A0A7U6GL77
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS00535
gene id: 1076588:TBH_RS00535
uniprot id: A0A7U6GG99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1076588:TBH RS11325
gene id: 1076588:TBH_RS11325
uniprot id: A0A7U6GK40
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1076588:TBH RS03655
gene id: 1076588:TBH_RS03655
uniprot id: A0A7U6GHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1076588:TBH RS13280
gene id: 1076588:TBH_RS13280
uniprot id: A0A7U6GKS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1076588:TBH RS02945
gene id: 1076588:TBH_RS02945
uniprot id: A0A7U6GH82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1076588:TBH RS06835
gene id: 1076588:TBH_RS06835
uniprot id: A0A7U6JHF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1076588:TBH RS10600
gene id: 1076588:TBH_RS10600
uniprot id: A0A7U6JI51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1076588:TBH RS11105
gene id: 1076588:TBH_RS11105
uniprot id: A0A7U6GK04
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS14655
gene id: 1076588:TBH_RS14655
uniprot id: A0A7U6GLK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1076588:TBH RS13420
gene id: 1076588:TBH_RS13420
uniprot id: A0A7U6GL41
names: Similarity
messages: Belongs to the GSP E family.

1076588:TBH RS02465
gene id: 1076588:TBH_RS02465
uniprot id: A0A7U6JH72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1076588:TBH RS02830
gene id: 1076588:TBH_RS02830
uniprot id: A0A7U6JGH4
names: Similarity
messages: Belongs to the UPF0102 family.

1076588:TBH RS03520
gene id: 1076588:TBH_RS03520
uniprot id: A0A7U6GH89
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1076588:TBH RS05785
gene id: 1076588:TBH_RS05785
uniprot id: A0A7U6GI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1076588:TBH RS01005
gene id: 1076588:TBH_RS01005
uniprot id: A0A7U6GGE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1076588:TBH RS01580
gene id: 1076588:TBH_RS01580
uniprot id: A0A7U6GGM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1076588:TBH RS00290
gene id: 1076588:TBH_RS00290
uniprot id: A0A7U6GG45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1076588:TBH RS02965
gene id: 1076588:TBH_RS02965
uniprot id: A0A7U6GH19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1076588:TBH RS03660
gene id: 1076588:TBH_RS03660
uniprot id: A0A7U6GHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1076588:TBH RS02455
gene id: 1076588:TBH_RS02455
uniprot id: A0A7U6JGD6
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02255
gene id: 1076588:TBH_RS02255
uniprot id: A0A7U6GGW6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1076588:TBH RS12455
gene id: 1076588:TBH_RS12455
uniprot id: A0A7U6GKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS02100
gene id: 1076588:TBH_RS02100
uniprot id: A0A7U6GGW9
names: Similarity
messages: Belongs to the Smg family.

1076588:TBH RS14765
gene id: 1076588:TBH_RS14765
uniprot id: A0A7U6GLC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1076588:TBH RS01225
gene id: 1076588:TBH_RS01225
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS11450
gene id: 1076588:TBH_RS11450
uniprot id: A0A7U6JIT7
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS05040
gene id: 1076588:TBH_RS05040
uniprot id: A0A7U6GHT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1076588:TBH RS01130
gene id: 1076588:TBH_RS01130
uniprot id: A0A7U6JGV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1076588:TBH RS06990
gene id: 1076588:TBH_RS06990
uniprot id: A0A7U6GII1
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1076588:TBH RS03445
gene id: 1076588:TBH_RS03445
uniprot id: A0A7U6GH79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS15450
gene id: 1076588:TBH_RS15450
uniprot id: A0A7U6JIU4
names: Similarity
messages: Belongs to the hemerythrin family.

1076588:TBH RS12990
gene id: 1076588:TBH_RS12990
uniprot id: A0A7U6JIL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS00985
gene id: 1076588:TBH_RS00985
uniprot id: A0A7U6GGD6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS11830
gene id: 1076588:TBH_RS11830
uniprot id: A0A7U6JIW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1076588:TBH RS13490
gene id: 1076588:TBH_RS13490
uniprot id: A0A7U6GL01
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1076588:TBH RS08455
gene id: 1076588:TBH_RS08455
uniprot id: A0A7U6GJ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1076588:TBH RS09720
gene id: 1076588:TBH_RS09720
uniprot id: A0A7U6GJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1076588:TBH RS06000
gene id: 1076588:TBH_RS06000
uniprot id: A0A7U6JHV0
names: Subcellular Location Annotation
messages: Cytoplasm

1076588:TBH RS03495
gene id: 1076588:TBH_RS03495
uniprot id: A0A7U6GHC8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1076588:TBH RS08825
gene id: 1076588:TBH_RS08825
uniprot id: A0A7U6GJ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1076588:TBH RS11875
gene id: 1076588:TBH_RS11875
uniprot id: A0A7U6GK93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1076588:TBH RS01045
gene id: 1076588:TBH_RS01045
uniprot id: A0A7U6JFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1076588:TBH RS06860
gene id: 1076588:TBH_RS06860
uniprot id: A0A7U6GIG9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1076588:TBH RS09745
gene id: 1076588:TBH_RS09745
uniprot id: A0A7U6JIF0
names: Similarity
messages: Belongs to the YciI family.

1076588:TBH RS07125
gene id: 1076588:TBH_RS07125
uniprot id: A0A7U6GIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS01050
gene id: 1076588:TBH_RS01050
uniprot id: A0A7U6JGR2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1076588:TBH RS00625
gene id: 1076588:TBH_RS00625
uniprot id: A0A7U6GG98
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS04480
gene id: 1076588:TBH_RS04480
uniprot id: A0A7U6GHN2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1076588:TBH RS10860
gene id: 1076588:TBH_RS10860
uniprot id: A0A7U6JI01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS08915
gene id: 1076588:TBH_RS08915
uniprot id: A0A7U6GJA8
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1076588:TBH RS07740
gene id: 1076588:TBH_RS07740
uniprot id: A0A7U6GIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1076588:TBH RS06305
gene id: 1076588:TBH_RS06305
uniprot id: A0A7U6GIC2
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS07530
gene id: 1076588:TBH_RS07530
uniprot id: A0A7U6GIT1
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS07185
gene id: 1076588:TBH_RS07185
uniprot id: A0A7U6GIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1076588:TBH RS12915
gene id: 1076588:TBH_RS12915
uniprot id: A0A7U6JJ32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1076588:TBH RS05140
gene id: 1076588:TBH_RS05140
uniprot id: A0A7U6JH19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS12140
gene id: 1076588:TBH_RS12140
uniprot id: A0A7U6JI83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS08680
gene id: 1076588:TBH_RS08680
uniprot id: A0A7U6GJ73
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1076588:TBH RS05280
gene id: 1076588:TBH_RS05280
uniprot id: A0A7U6GHV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1076588:TBH RS00885
gene id: 1076588:TBH_RS00885
uniprot id: A0A7U6JGP9
names: Similarity
messages: Belongs to the glutamate synthase family.

1076588:TBH RS05200
gene id: 1076588:TBH_RS05200
uniprot id: A0A7U6GHW3
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS01645
gene id: 1076588:TBH_RS01645
uniprot id: A0A7U6GGN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1076588:TBH RS04805
gene id: 1076588:TBH_RS04805
uniprot id: A0A7U6JGZ6
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS09075
gene id: 1076588:TBH_RS09075
uniprot id: A0A7U6GJ66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1076588:TBH RS09200
gene id: 1076588:TBH_RS09200
uniprot id: A0A7U6JHP8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1076588:TBH RS06540
gene id: 1076588:TBH_RS06540
uniprot id: A0A7U6JHY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1076588:TBH RS05800
gene id: 1076588:TBH_RS05800
uniprot id: A0A7U6GI53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1076588:TBH RS04380
gene id: 1076588:TBH_RS04380
uniprot id: A0A7U6GHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1076588:TBH RS12605
gene id: 1076588:TBH_RS12605
uniprot id: A0A7U6JKE8
names: Similarity
messages: Belongs to the HSP15 family.

1076588:TBH RS07905
gene id: 1076588:TBH_RS07905
uniprot id: A0A7U6GIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1076588:TBH RS08140
gene id: 1076588:TBH_RS08140
uniprot id: A0A7U6GIV7
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS05470
gene id: 1076588:TBH_RS05470
uniprot id: A0A7U6GI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1076588:TBH RS01565
gene id: 1076588:TBH_RS01565
uniprot id: A0A7U6GGK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1076588:TBH RS13155
gene id: 1076588:TBH_RS13155
uniprot id: A0A7U6JJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1076588:TBH RS01345
gene id: 1076588:TBH_RS01345
uniprot id: A0A7U6GGH7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1076588:TBH RS09070
gene id: 1076588:TBH_RS09070
uniprot id: A0A7U6GJ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1076588:TBH RS10295
gene id: 1076588:TBH_RS10295
uniprot id: A0A7U6JHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1076588:TBH RS14145
gene id: 1076588:TBH_RS14145
uniprot id: A0A7U6JL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1076588:TBH RS08935
gene id: 1076588:TBH_RS08935
uniprot id: A0A7U6GJ45
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1076588:TBH RS11095
gene id: 1076588:TBH_RS11095
uniprot id: A0A7U6GK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1076588:TBH RS00455
gene id: 1076588:TBH_RS00455
uniprot id: A0A7U6GG73
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1076588:TBH RS12160
gene id: 1076588:TBH_RS12160
uniprot id: A0A7U6GKE1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1076588:TBH RS09165
gene id: 1076588:TBH_RS09165
uniprot id: A0A7U6GJ76
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1076588:TBH RS09365
gene id: 1076588:TBH_RS09365
uniprot id: A0A7U6JHQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1076588:TBH RS08155
gene id: 1076588:TBH_RS08155
uniprot id: A0A7U6GIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1076588:TBH RS02220
gene id: 1076588:TBH_RS02220
uniprot id: A0A7U6JH45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1076588:TBH RS10780
gene id: 1076588:TBH_RS10780
uniprot id: A0A7U6JHZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1076588:TBH RS04485
gene id: 1076588:TBH_RS04485
uniprot id: A0A7U6JGY0
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS10960
gene id: 1076588:TBH_RS10960
uniprot id: A0A7U6GK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1076588:TBH RS01630
gene id: 1076588:TBH_RS01630
uniprot id: A0A7U6JHI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1076588:TBH RS13685
gene id: 1076588:TBH_RS13685
uniprot id: A0A7U6GL10
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1076588:TBH RS11510
gene id: 1076588:TBH_RS11510
uniprot id: A0A7U6GK77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1076588:TBH RS11605
gene id: 1076588:TBH_RS11605
uniprot id: A0A7U6JIS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1076588:TBH RS01425
gene id: 1076588:TBH_RS01425
uniprot id: A0A7U6GGI1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1076588:TBH RS06375
gene id: 1076588:TBH_RS06375
uniprot id: A0A7U6GIB5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1076588:TBH RS03035
gene id: 1076588:TBH_RS03035
uniprot id: A0A7U6GH49
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1076588:TBH RS01690
gene id: 1076588:TBH_RS01690
uniprot id: A0A7U6JGW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1076588:TBH RS00445
gene id: 1076588:TBH_RS00445
uniprot id: A0A7U6GG76
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS12910
gene id: 1076588:TBH_RS12910
uniprot id: A0A7U6JIL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1076588:TBH RS06605
gene id: 1076588:TBH_RS06605
uniprot id: A0A7U6JHE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS10595
gene id: 1076588:TBH_RS10595
uniprot id: A0A7U6GJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1076588:TBH RS00045
gene id: 1076588:TBH_RS00045
uniprot id: A0A7U6GG33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1076588:TBH RS08520
gene id: 1076588:TBH_RS08520
uniprot id: A0A7U6GJ71
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1076588:TBH RS03700
gene id: 1076588:TBH_RS03700
uniprot id: A0A7U6JHG2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1076588:TBH RS01315
gene id: 1076588:TBH_RS01315
uniprot id: A0A7U6GGJ3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1076588:TBH RS08375
gene id: 1076588:TBH_RS08375
uniprot id: A0A7U6GJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS15550
gene id: 1076588:TBH_RS15550
uniprot id: A0A7U6GJW1
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1076588:TBH RS11465
gene id: 1076588:TBH_RS11465
uniprot id: A0A7U6GK49
names: Similarity
messages: Belongs to the UPF0178 family.

1076588:TBH RS02270
gene id: 1076588:TBH_RS02270
uniprot id: A0A7U6GGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1076588:TBH RS08320
gene id: 1076588:TBH_RS08320
uniprot id: A0A7U6GJ02
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1076588:TBH RS13960
gene id: 1076588:TBH_RS13960
uniprot id: A0A7U6JIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1076588:TBH RS01635
gene id: 1076588:TBH_RS01635
uniprot id: A0A7U6GGK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1076588:TBH RS07980
gene id: 1076588:TBH_RS07980
uniprot id: A0A7U6GIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1076588:TBH RS00750
gene id: 1076588:TBH_RS00750
uniprot id: A0A7U6GGB4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1076588:TBH RS09355
gene id: 1076588:TBH_RS09355
uniprot id: A0A7U6JIC6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1076588:TBH RS06475
gene id: 1076588:TBH_RS06475
uniprot id: A0A7U6JIF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1076588:TBH RS01555
gene id: 1076588:TBH_RS01555
uniprot id: A0A7U6JHI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1076588:TBH RS07955
gene id: 1076588:TBH_RS07955
uniprot id: A0A7U6GIW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1076588:TBH RS00840
gene id: 1076588:TBH_RS00840
uniprot id: A0A7U6GGC4
names: Similarity
messages: Belongs to the citrate synthase family.

1076588:TBH RS09040
gene id: 1076588:TBH_RS09040
uniprot id: A0A7U6JHN8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1076588:TBH RS12380
gene id: 1076588:TBH_RS12380
uniprot id: A0A7U6GKK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1076588:TBH RS05525
gene id: 1076588:TBH_RS05525
uniprot id: A0A7U6JHP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1076588:TBH RS01065
gene id: 1076588:TBH_RS01065
uniprot id: A0A7U6JHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1076588:TBH RS01625
gene id: 1076588:TBH_RS01625
uniprot id: A0A7U6JFX1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1076588:TBH RS04355
gene id: 1076588:TBH_RS04355
uniprot id: A0A7U6GHM6
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1076588:TBH RS00550
gene id: 1076588:TBH_RS00550
uniprot id: A0A7U6GG65
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1076588:TBH RS00995
gene id: 1076588:TBH_RS00995
uniprot id: A0A7U6GGF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1076588:TBH RS00405
gene id: 1076588:TBH_RS00405
uniprot id: A0A7U6GG61
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1076588:TBH RS00745
gene id: 1076588:TBH_RS00745
uniprot id: A0A7U6JHD2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1076588:TBH RS11615
gene id: 1076588:TBH_RS11615
uniprot id: A0A7U6JI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS03140
gene id: 1076588:TBH_RS03140
uniprot id: A0A7U6GH40
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1076588:TBH RS10900
gene id: 1076588:TBH_RS10900
uniprot id: A0A7U6GJX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS03745
gene id: 1076588:TBH_RS03745
uniprot id: A0A7U6GHE1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1076588:TBH RS00765
gene id: 1076588:TBH_RS00765
uniprot id: A0A7U6GGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1076588:TBH RS14590
gene id: 1076588:TBH_RS14590
uniprot id: A0A7U6GL94
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS11005
gene id: 1076588:TBH_RS11005
uniprot id: A0A7U6JJM2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1076588:TBH RS02980
gene id: 1076588:TBH_RS02980
uniprot id: A0A7U6JGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1076588:TBH RS06490
gene id: 1076588:TBH_RS06490
uniprot id: A0A7U6GIF5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1076588:TBH RS09885
gene id: 1076588:TBH_RS09885
uniprot id: A0A7U6GJP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1076588:TBH RS10270
gene id: 1076588:TBH_RS10270
uniprot id: A0A7U6GJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS07535
gene id: 1076588:TBH_RS07535
uniprot id: A0A7U6GIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1076588:TBH RS03635
gene id: 1076588:TBH_RS03635
uniprot id: A0A7U6GHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1076588:TBH RS13135
gene id: 1076588:TBH_RS13135
uniprot id: A0A7U6GKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1076588:TBH RS06740
gene id: 1076588:TBH_RS06740
uniprot id: A0A7U6GIE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1076588:TBH RS01115
gene id: 1076588:TBH_RS01115
uniprot id: A0A7U6GGE7
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS08200
gene id: 1076588:TBH_RS08200
uniprot id: A0A7U6GJ23
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS03400
gene id: 1076588:TBH_RS03400
uniprot id: A0A7U6JGH0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1076588:TBH RS04630
gene id: 1076588:TBH_RS04630
uniprot id: A0A7U6GHR2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1076588:TBH RS01615
gene id: 1076588:TBH_RS01615
uniprot id: A0A7U6JGV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1076588:TBH RS09590
gene id: 1076588:TBH_RS09590
uniprot id: A0A7U6JIE2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1076588:TBH RS13100
gene id: 1076588:TBH_RS13100
uniprot id: A0A7U6GKP4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1076588:TBH RS04435
gene id: 1076588:TBH_RS04435
uniprot id: A0A7U6GHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1076588:TBH RS06155
gene id: 1076588:TBH_RS06155
uniprot id: A0A7U6JHB0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1076588:TBH RS01715
gene id: 1076588:TBH_RS01715
uniprot id: A0A7U6GGM3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1076588:TBH RS07675
gene id: 1076588:TBH_RS07675
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS05170
gene id: 1076588:TBH_RS05170
uniprot id: A0A7U6GHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS11415
gene id: 1076588:TBH_RS11415
uniprot id: A0A7U6GK45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1076588:TBH RS03420
gene id: 1076588:TBH_RS03420
uniprot id: A0A7U6GHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1076588:TBH RS06280
gene id: 1076588:TBH_RS06280
uniprot id: A0A7U6GIA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS00355
gene id: 1076588:TBH_RS00355
uniprot id: A0A7U6JHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1076588:TBH RS12070
gene id: 1076588:TBH_RS12070
uniprot id: A0A7U6JK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1076588:TBH RS00190
gene id: 1076588:TBH_RS00190
uniprot id: A0A7U6JGN1
names: PTM
messages: Binds 1 heme group per subunit.

1076588:TBH RS10035
gene id: 1076588:TBH_RS10035
uniprot id: A0A7U6GJI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1076588:TBH RS02690
gene id: 1076588:TBH_RS02690
uniprot id: A0A7U6JH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS07655
gene id: 1076588:TBH_RS07655
uniprot id: A0A7U6JHK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1076588:TBH RS13875
gene id: 1076588:TBH_RS13875
uniprot id: A0A7U6JJG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS01870
gene id: 1076588:TBH_RS01870
uniprot id: A0A7U6GGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1076588:TBH RS05590
gene id: 1076588:TBH_RS05590
uniprot id: A0A7U6GI40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1076588:TBH RS02470
gene id: 1076588:TBH_RS02470
uniprot id: A0A7U6JG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1076588:TBH RS05830
gene id: 1076588:TBH_RS05830
uniprot id: A0A7U6GI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1076588:TBH RS06285
gene id: 1076588:TBH_RS06285
uniprot id: A0A7U6GI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1076588:TBH RS01205
gene id: 1076588:TBH_RS01205
uniprot id: A0A7U6JGW3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1076588:TBH RS13195
gene id: 1076588:TBH_RS13195
uniprot id: A0A7U6GL13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1076588:TBH RS07045
gene id: 1076588:TBH_RS07045
uniprot id: A0A7U6GIL1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1076588:TBH RS00390
gene id: 1076588:TBH_RS00390
uniprot id: A0A7U6GG53
names: Similarity
messages: Belongs to the YjdM family.

1076588:TBH RS13465
gene id: 1076588:TBH_RS13465
uniprot id: A0A7U6JJG4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1076588:TBH RS05445
gene id: 1076588:TBH_RS05445
uniprot id: A0A7U6JHN5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1076588:TBH RS02780
gene id: 1076588:TBH_RS02780
uniprot id: A0A7U6GH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1076588:TBH RS12245
gene id: 1076588:TBH_RS12245
uniprot id: A0A7U6GKF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1076588:TBH RS04300
gene id: 1076588:TBH_RS04300
uniprot id: A0A7U6GHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS09615
gene id: 1076588:TBH_RS09615
uniprot id: A0A7U6GJJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1076588:TBH RS04065
gene id: 1076588:TBH_RS04065
uniprot id: A0A7U6GHH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS02825
gene id: 1076588:TBH_RS02825
uniprot id: A0A7U6GH05
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1076588:TBH RS10430
gene id: 1076588:TBH_RS10430
uniprot id: A0A7U6GJS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1076588:TBH RS07320
gene id: 1076588:TBH_RS07320
uniprot id: A0A7U6JI08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS02910
gene id: 1076588:TBH_RS02910
uniprot id: A0A7U6JH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1076588:TBH RS02160
gene id: 1076588:TBH_RS02160
uniprot id: A0A7U6GGT1
names: Similarity
messages: Belongs to the UPF0234 family.

1076588:TBH RS01670
gene id: 1076588:TBH_RS01670
uniprot id: A0A7U6GGK9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1076588:TBH RS07145
gene id: 1076588:TBH_RS07145
uniprot id: A0A7U6GIJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1076588:TBH RS01430
gene id: 1076588:TBH_RS01430
uniprot id: A0A7U6JG25
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1076588:TBH RS12905
gene id: 1076588:TBH_RS12905
uniprot id: A0A7U6GKR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1076588:TBH RS00525
gene id: 1076588:TBH_RS00525
uniprot id: A0A7U6GG69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1076588:TBH RS05290
gene id: 1076588:TBH_RS05290
uniprot id: A0A7U6JH36
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1076588:TBH RS10965
gene id: 1076588:TBH_RS10965
uniprot id: A0A7U6GJY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1076588:TBH RS05825
gene id: 1076588:TBH_RS05825
uniprot id: A0A7U6GI38
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1076588:TBH RS08500
gene id: 1076588:TBH_RS08500
uniprot id: A0A7U6JHK2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1076588:TBH RS07570
gene id: 1076588:TBH_RS07570
uniprot id: A0A7U6JHJ5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS11230
gene id: 1076588:TBH_RS11230
uniprot id: A0A7U6JIR4
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS02715
gene id: 1076588:TBH_RS02715
uniprot id: A0A7U6GH34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1076588:TBH RS05740
gene id: 1076588:TBH_RS05740
uniprot id: A0A7U6GI57
names: Subunit
messages: Monomer.

1076588:TBH RS01640
gene id: 1076588:TBH_RS01640
uniprot id: A0A7U6GGL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1076588:TBH RS01395
gene id: 1076588:TBH_RS01395
uniprot id: A0A7U6GGL4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1076588:TBH RS03855
gene id: 1076588:TBH_RS03855
uniprot id: A0A7U6JHH1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1076588:TBH RS10235
gene id: 1076588:TBH_RS10235
uniprot id: A0A7U6GJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS09435
gene id: 1076588:TBH_RS09435
uniprot id: A0A7U6JID1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS06940
gene id: 1076588:TBH_RS06940
uniprot id: A0A7U6JHA7
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS14495
gene id: 1076588:TBH_RS14495
uniprot id: A0A7U6GLC0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1076588:TBH RS08735
gene id: 1076588:TBH_RS08735
uniprot id: A0A7U6JIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1076588:TBH RS12130
gene id: 1076588:TBH_RS12130
uniprot id: A0A7U6JIW4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1076588:TBH RS06710
gene id: 1076588:TBH_RS06710
uniprot id: A0A7U6GIH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS05970
gene id: 1076588:TBH_RS05970
uniprot id: A0A7U6GI77
names: Similarity
messages: Belongs to the skp family.

1076588:TBH RS06565
gene id: 1076588:TBH_RS06565
uniprot id: A0A7U6GIG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1076588:TBH RS07785
gene id: 1076588:TBH_RS07785
uniprot id: A0A7U6GIV0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1076588:TBH RS14300
gene id: 1076588:TBH_RS14300
uniprot id: A0A7U6JIV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1076588:TBH RS05360
gene id: 1076588:TBH_RS05360
uniprot id: A0A7U6GHY1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1076588:TBH RS00770
gene id: 1076588:TBH_RS00770
uniprot id: A0A7U6GGE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1076588:TBH RS00220
gene id: 1076588:TBH_RS00220
uniprot id: A0A7U6GG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1076588:TBH RS09245
gene id: 1076588:TBH_RS09245
uniprot id: A0A7U6GJ93
names: Similarity
messages: Belongs to the TPP enzyme family.

1076588:TBH RS09880
gene id: 1076588:TBH_RS09880
uniprot id: A0A7U6GJL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1076588:TBH RS07830
gene id: 1076588:TBH_RS07830
uniprot id: A0A7U6GIY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS00070
gene id: 1076588:TBH_RS00070
uniprot id: A0A7U6GG09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1076588:TBH RS01585
gene id: 1076588:TBH_RS01585
uniprot id: A0A7U6GGM1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1076588:TBH RS10665
gene id: 1076588:TBH_RS10665
uniprot id: A0A7U6GJZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1076588:TBH RS12765
gene id: 1076588:TBH_RS12765
uniprot id: A0A7U6JKG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1076588:TBH RS04610
gene id: 1076588:TBH_RS04610
uniprot id: A0A7U6GHR5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1076588:TBH RS07305
gene id: 1076588:TBH_RS07305
uniprot id: A0A7U6GIP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1076588:TBH RS11660
gene id: 1076588:TBH_RS11660
uniprot id: A0A7U6GKA9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1076588:TBH RS02320
gene id: 1076588:TBH_RS02320
uniprot id: A0A7U6GGY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1076588:TBH RS14115
gene id: 1076588:TBH_RS14115
uniprot id: A0A7U6GL53
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1076588:TBH RS06495
gene id: 1076588:TBH_RS06495
uniprot id: A0A7U6GIE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1076588:TBH RS13440
gene id: 1076588:TBH_RS13440
uniprot id: A0A7U6GKZ3
names: Similarity
messages: Belongs to the UPF0235 family.

1076588:TBH RS09960
gene id: 1076588:TBH_RS09960
uniprot id: A0A7U6GJN6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1076588:TBH RS02515
gene id: 1076588:TBH_RS02515
uniprot id: A0A7U6GGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS06370
gene id: 1076588:TBH_RS06370
uniprot id: A0A7U6GIA4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1076588:TBH RS14790
gene id: 1076588:TBH_RS14790
uniprot id: A0A7U6JLK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS13390
gene id: 1076588:TBH_RS13390
uniprot id: A0A7U6JJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1076588:TBH RS07105
gene id: 1076588:TBH_RS07105
uniprot id: A0A7U6GIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1076588:TBH RS10145
gene id: 1076588:TBH_RS10145
uniprot id: A0A7U6JIJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1076588:TBH RS13190
gene id: 1076588:TBH_RS13190
uniprot id: A0A7U6GKQ1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1076588:TBH RS00060
gene id: 1076588:TBH_RS00060
uniprot id: A0A7U6GG08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1076588:TBH RS00610
gene id: 1076588:TBH_RS00610
uniprot id: A0A7U6GG96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1076588:TBH RS03260
gene id: 1076588:TBH_RS03260
uniprot id: A0A7U6GH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1076588:TBH RS10660
gene id: 1076588:TBH_RS10660
uniprot id: A0A7U6GJR0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1076588:TBH RS12295
gene id: 1076588:TBH_RS12295
uniprot id: A0A7U6JKA1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1076588:TBH RS11140
gene id: 1076588:TBH_RS11140
uniprot id: A0A7U6JIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1076588:TBH RS04730
gene id: 1076588:TBH_RS04730
uniprot id: A0A7U6JGZ1
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1076588:TBH RS13785
gene id: 1076588:TBH_RS13785
uniprot id: A0A7U6GL14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1076588:TBH RS06975
gene id: 1076588:TBH_RS06975
uniprot id: A0A7U6GIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1076588:TBH RS01800
gene id: 1076588:TBH_RS01800
uniprot id: A0A7U6GGS7
names: Similarity
messages: Belongs to the peptidase C56 family.

1076588:TBH RS10830
gene id: 1076588:TBH_RS10830
uniprot id: A0A7U6GJU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1076588:TBH RS09270
gene id: 1076588:TBH_RS09270
uniprot id: A0A7U6JHV4
names: Similarity
messages: Belongs to the threonine synthase family.

1076588:TBH RS12770
gene id: 1076588:TBH_RS12770
uniprot id: A0A7U6GKK7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1076588:TBH RS04425
gene id: 1076588:TBH_RS04425
uniprot id: A0A7U6JGR4
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1076588:TBH RS03980
gene id: 1076588:TBH_RS03980
uniprot id: A0A7U6GHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1076588:TBH RS00990
gene id: 1076588:TBH_RS00990
uniprot id: A0A7U6GGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1076588:TBH RS03465
gene id: 1076588:TBH_RS03465
uniprot id: A0A7U6JHA8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1076588:TBH RS14085
gene id: 1076588:TBH_RS14085
uniprot id: A0A7U6GL12
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1076588:TBH RS09380
gene id: 1076588:TBH_RS09380
uniprot id: A0A7U6GJG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1076588:TBH RS11020
gene id: 1076588:TBH_RS11020
uniprot id: A0A7U6GK05
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1076588:TBH RS13375
gene id: 1076588:TBH_RS13375
uniprot id: A0A7U6GKW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1076588:TBH RS08445
gene id: 1076588:TBH_RS08445
uniprot id: A0A7U6GJ55
names: Similarity
messages: Belongs to the ArsC family.

1076588:TBH RS00185
gene id: 1076588:TBH_RS00185
uniprot id: A0A7U6JGI6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1076588:TBH RS00695
gene id: 1076588:TBH_RS00695
uniprot id: A0A7U6GG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1076588:TBH RS11395
gene id: 1076588:TBH_RS11395
uniprot id: A0A7U6GK72
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS10950
gene id: 1076588:TBH_RS10950
uniprot id: A0A7U6GK32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1076588:TBH RS03455
gene id: 1076588:TBH_RS03455
uniprot id: A0A7U6GH86
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS15590
gene id: 1076588:TBH_RS15590
uniprot id: A0A7U6JH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1076588:TBH RS11855
gene id: 1076588:TBH_RS11855
uniprot id: A0A7U6GK99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS10550
gene id: 1076588:TBH_RS10550
uniprot id: A0A7U6GJT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1076588:TBH RS06500
gene id: 1076588:TBH_RS06500
uniprot id: A0A7U6GIF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1076588:TBH RS08970
gene id: 1076588:TBH_RS08970
uniprot id: A0A7U6JIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1076588:TBH RS01155
gene id: 1076588:TBH_RS01155
uniprot id: A0A7U6GGH5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1076588:TBH RS01545
gene id: 1076588:TBH_RS01545
uniprot id: A0A7U6JGY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1076588:TBH RS10685
gene id: 1076588:TBH_RS10685
uniprot id: A0A7U6JIM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1076588:TBH RS00670
gene id: 1076588:TBH_RS00670
uniprot id: A0A7U6JHC8
names: Similarity
messages: Belongs to the MoaD family.

1076588:TBH RS08540
gene id: 1076588:TBH_RS08540
uniprot id: A0A7U6GJ52
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1076588:TBH RS12525
gene id: 1076588:TBH_RS12525
uniprot id: A0A7U6JIA7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1076588:TBH RS06945
gene id: 1076588:TBH_RS06945
uniprot id: A0A7U6JII3
names: Subcellular Location Annotation
messages: Membrane

1076588:TBH RS05215
gene id: 1076588:TBH_RS05215
uniprot id: A0A7U6JH27
names: Similarity
messages: Belongs to the PspA/IM30 family.

1076588:TBH RS10890
gene id: 1076588:TBH_RS10890
uniprot id: A0A7U6GJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1076588:TBH RS10785
gene id: 1076588:TBH_RS10785
uniprot id: A0A7U6JJJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1076588:TBH RS05375
gene id: 1076588:TBH_RS05375
uniprot id: A0A7U6JH43
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1076588:TBH RS15425
gene id: 1076588:TBH_RS15425
uniprot id: A0A7U6JJJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1076588:TBH RS13170
gene id: 1076588:TBH_RS13170
uniprot id: A0A7U6JKS4
names: Similarity
messages: Belongs to the P(II) protein family.

1076588:TBH RS01705
gene id: 1076588:TBH_RS01705
uniprot id: A0A7U6JHJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1076588:TBH RS01370
gene id: 1076588:TBH_RS01370
uniprot id: A0A7U6JFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1076588:TBH RS00615
gene id: 1076588:TBH_RS00615
uniprot id: A0A7U6GGA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1076588:TBH RS03430
gene id: 1076588:TBH_RS03430
uniprot id: A0A7U6GHA1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1076588:TBH RS02355
gene id: 1076588:TBH_RS02355
uniprot id: A0A7U6GGV6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1076588:TBH RS10105
gene id: 1076588:TBH_RS10105
uniprot id: A0A7U6GJM5
names: Similarity
messages: Belongs to the UPF0260 family.

1076588:TBH RS01810
gene id: 1076588:TBH_RS01810
uniprot id: A0A7U6GGP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1076588:TBH RS14105
gene id: 1076588:TBH_RS14105
uniprot id: A0A7U6GL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1076588:TBH RS00960
gene id: 1076588:TBH_RS00960
uniprot id: A0A7U6JFW8
names: Similarity
messages: Belongs to the peptidase U62 family.

1076588:TBH RS00135
gene id: 1076588:TBH_RS00135
uniprot id: A0A7U6GLC7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1076588:TBH RS09375
gene id: 1076588:TBH_RS09375
uniprot id: A0A7U6GJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1076588:TBH RS04840
gene id: 1076588:TBH_RS04840
uniprot id: A0A7U6GHU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1076588:TBH RS10620
gene id: 1076588:TBH_RS10620
uniprot id: A0A7U6JJH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1076588:TBH RS07120
gene id: 1076588:TBH_RS07120
uniprot id: A0A7U6GIM4
names: Subcellular Location Annotation
messages: Cytoplasm

1076588:TBH RS10415
gene id: 1076588:TBH_RS10415
uniprot id: A0A7U6GJQ8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1076588:TBH RS06290
gene id: 1076588:TBH_RS06290
uniprot id: A0A7U6GIC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1076588:TBH RS05600
gene id: 1076588:TBH_RS05600
uniprot id: A0A7U6JHP5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.