1074467:JP39 RS02220
gene id: 1074467:JP39_RS02220
uniprot id: A0A0K2LAH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1074467:JP39 RS00500
gene id: 1074467:JP39_RS00500
uniprot id: A0A0K2L9K4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1074467:JP39 RS04410
gene id: 1074467:JP39_RS04410
uniprot id: A0A0K2LBI7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1074467:JP39 RS06860
gene id: 1074467:JP39_RS06860
uniprot id: A0A0K2LD55
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1074467:JP39 RS11880
gene id: 1074467:JP39_RS11880
uniprot id: A0A0K2LFM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS03435
gene id: 1074467:JP39_RS03435
uniprot id: A0A0K2LBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS07640
gene id: 1074467:JP39_RS07640
uniprot id: A0A0K2LD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1074467:JP39 RS07240
gene id: 1074467:JP39_RS07240
uniprot id: A0A0K2LCZ5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1074467:JP39 RS00300
gene id: 1074467:JP39_RS00300
uniprot id: A0A0K2L9J6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS01370
gene id: 1074467:JP39_RS01370
uniprot id: A0A0K2LA05
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS09450
gene id: 1074467:JP39_RS09450
uniprot id: A0A0K2LE37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1074467:JP39 RS01870
gene id: 1074467:JP39_RS01870
uniprot id: A0A0K2LAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1074467:JP39 RS04450
gene id: 1074467:JP39_RS04450
uniprot id: A0A0K2LBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1074467:JP39 RS12075
gene id: 1074467:JP39_RS12075
uniprot id: A0A0K2LFG0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06605
gene id: 1074467:JP39_RS06605
uniprot id: A0A0K2LD07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS07320
gene id: 1074467:JP39_RS07320
uniprot id: A0A0K2LD09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1074467:JP39 RS04865
gene id: 1074467:JP39_RS04865
uniprot id: A0A0K2LC35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1074467:JP39 RS04805
gene id: 1074467:JP39_RS04805
uniprot id: A0A0K2LBP7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS04360
gene id: 1074467:JP39_RS04360
uniprot id: A0A0K2LG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11755
gene id: 1074467:JP39_RS11755
uniprot id: A0A0K2LFA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1074467:JP39 RS00205
gene id: 1074467:JP39_RS00205
uniprot id: A0A0K2L9E6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1074467:JP39 RS07835
gene id: 1074467:JP39_RS07835
uniprot id: A0A0K2LD96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1074467:JP39 RS08180
gene id: 1074467:JP39_RS08180
uniprot id: A0A0K2LDF5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06350
gene id: 1074467:JP39_RS06350
uniprot id: A0A0K2LCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11220
gene id: 1074467:JP39_RS11220
uniprot id: A0A0K2LFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1074467:JP39 RS01900
gene id: 1074467:JP39_RS01900
uniprot id: A0A0K2LAA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1074467:JP39 RS00900
gene id: 1074467:JP39_RS00900
uniprot id: A0A0K2L9U9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1074467:JP39 RS05545
gene id: 1074467:JP39_RS05545
uniprot id: A0A0K2LC38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1074467:JP39 RS01790
gene id: 1074467:JP39_RS01790
uniprot id: A0A0K2LFP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS03020
gene id: 1074467:JP39_RS03020
uniprot id: A0A0K2LAU6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06330
gene id: 1074467:JP39_RS06330
uniprot id: A0A0K2LCH7
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1074467:JP39 RS11140
gene id: 1074467:JP39_RS11140
uniprot id: A0A0K2LFA0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08755
gene id: 1074467:JP39_RS08755
uniprot id: A0A0K2LE24
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1074467:JP39 RS02415
gene id: 1074467:JP39_RS02415
uniprot id: A0A0K2LAK8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1074467:JP39 RS01070
gene id: 1074467:JP39_RS01070
uniprot id: A0A0K2L9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1074467:JP39 RS11535
gene id: 1074467:JP39_RS11535
uniprot id: A0A0K2LFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1074467:JP39 RS04460
gene id: 1074467:JP39_RS04460
uniprot id: A0A0K2LBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1074467:JP39 RS08330
gene id: 1074467:JP39_RS08330
uniprot id: A0A0K2LDI0
names: Similarity
names: Subunit
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.
messages: Monomer.

1074467:JP39 RS10610
gene id: 1074467:JP39_RS10610
uniprot id: A0A0K2LEN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1074467:JP39 RS11835
gene id: 1074467:JP39_RS11835
uniprot id: A0A0K2LFB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS10155
gene id: 1074467:JP39_RS10155
uniprot id: A0A0K2LEF0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10845
gene id: 1074467:JP39_RS10845
uniprot id: A0A0K2LEW2
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS06975
gene id: 1074467:JP39_RS06975
uniprot id: A0A0K2LCV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1074467:JP39 RS04910
gene id: 1074467:JP39_RS04910
uniprot id: A0A0K2LBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1074467:JP39 RS05800
gene id: 1074467:JP39_RS05800
uniprot id: A0A0K2LCK4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS10550
gene id: 1074467:JP39_RS10550
uniprot id: A0A0K2LEL9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1074467:JP39 RS08995
gene id: 1074467:JP39_RS08995
uniprot id: A0A0K2LDY6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1074467:JP39 RS10930
gene id: 1074467:JP39_RS10930
uniprot id: A0A0K2LEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1074467:JP39 RS01355
gene id: 1074467:JP39_RS01355
uniprot id: A0A0K2LA11
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1074467:JP39 RS00355
gene id: 1074467:JP39_RS00355
uniprot id: A0A0K2L9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1074467:JP39 RS10375
gene id: 1074467:JP39_RS10375
uniprot id: A0A0K2LEX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS03510
gene id: 1074467:JP39_RS03510
uniprot id: A0A0K2LB30
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS02380
gene id: 1074467:JP39_RS02380
uniprot id: A0A0K2LAM3
names: Similarity
messages: Belongs to the peptidase C1 family.

1074467:JP39 RS01770
gene id: 1074467:JP39_RS01770
uniprot id: A0A0K2LA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1074467:JP39 RS01785
gene id: 1074467:JP39_RS01785
uniprot id: A0A0K2LA75
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1074467:JP39 RS07185
gene id: 1074467:JP39_RS07185
uniprot id: A0A0K2LCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1074467:JP39 RS00395
gene id: 1074467:JP39_RS00395
uniprot id: A0A0K2L9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1074467:JP39 RS04060
gene id: 1074467:JP39_RS04060
uniprot id: A0A0K2LBB9
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1074467:JP39 RS06985
gene id: 1074467:JP39_RS06985
uniprot id: A0A0K2LCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1074467:JP39 RS10710
gene id: 1074467:JP39_RS10710
uniprot id: A0A0K2LF20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS12740
gene id: 1074467:JP39_RS12740
uniprot id: A0A0K2LCP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1074467:JP39 RS08430
gene id: 1074467:JP39_RS08430
uniprot id: A0A0K2LDW4
names: Subcellular Location Annotation
messages: Cell membrane

1074467:JP39 RS06995
gene id: 1074467:JP39_RS06995
uniprot id: A0A0K2LD80
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1074467:JP39 RS00095
gene id: 1074467:JP39_RS00095
uniprot id: A0A0K2L9C8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02820
gene id: 1074467:JP39_RS02820
uniprot id: A0A0K2LAT6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1074467:JP39 RS01595
gene id: 1074467:JP39_RS01595
uniprot id: A0A0K2LA40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1074467:JP39 RS05885
gene id: 1074467:JP39_RS05885
uniprot id: A0A0K2LCA1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06015
gene id: 1074467:JP39_RS06015
uniprot id: A0A0K2LCC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS00590
gene id: 1074467:JP39_RS00590
uniprot id: A0A0K2L9P9
names: Similarity
messages: Belongs to the EamA transporter family.

1074467:JP39 RS08800
gene id: 1074467:JP39_RS08800
uniprot id: A0A0K2LDR9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1074467:JP39 RS01865
gene id: 1074467:JP39_RS01865
uniprot id: A0A0K2LA85
names: Similarity
messages: Belongs to the UPF0177 family.

1074467:JP39 RS03175
gene id: 1074467:JP39_RS03175
uniprot id: A0A0K2LB73
names: Similarity
messages: Belongs to the GSP E family.

1074467:JP39 RS04625
gene id: 1074467:JP39_RS04625
uniprot id: A0A0K2LBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11575
gene id: 1074467:JP39_RS11575
uniprot id: A0A0K2LF68
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1074467:JP39 RS08750
gene id: 1074467:JP39_RS08750
uniprot id: A0A0K2LDQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1074467:JP39 RS07860
gene id: 1074467:JP39_RS07860
uniprot id: A0A0K2LDA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS05005
gene id: 1074467:JP39_RS05005
uniprot id: A0A0K2LBX9
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06270
gene id: 1074467:JP39_RS06270
uniprot id: A0A0K2LCH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS09995
gene id: 1074467:JP39_RS09995
uniprot id: A0A0K2LEQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05375
gene id: 1074467:JP39_RS05375
uniprot id: A0A0K2LCC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS04760
gene id: 1074467:JP39_RS04760
uniprot id: A0A0K2LC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS09570
gene id: 1074467:JP39_RS09570
uniprot id: A0A0K2LE56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1074467:JP39 RS04515
gene id: 1074467:JP39_RS04515
uniprot id: A0A0K2LBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1074467:JP39 RS01730
gene id: 1074467:JP39_RS01730
uniprot id: A0A0K2LA81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05015
gene id: 1074467:JP39_RS05015
uniprot id: A0A0K2LBT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS07510
gene id: 1074467:JP39_RS07510
uniprot id: A0A0K2LG58
names: Similarity
messages: Belongs to the glutamine synthetase family.

1074467:JP39 RS05185
gene id: 1074467:JP39_RS05185
uniprot id: A0A0K2LBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11200
gene id: 1074467:JP39_RS11200
uniprot id: A0A0K2LEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1074467:JP39 RS04405
gene id: 1074467:JP39_RS04405
uniprot id: A0A0K2LBV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS08155
gene id: 1074467:JP39_RS08155
uniprot id: A0A0K2LDF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1074467:JP39 RS01195
gene id: 1074467:JP39_RS01195
uniprot id: A0A0K2LA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1074467:JP39 RS04950
gene id: 1074467:JP39_RS04950
uniprot id: A0A0K2LBW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1074467:JP39 RS00230
gene id: 1074467:JP39_RS00230
uniprot id: A0A0K2L9F1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1074467:JP39 RS01875
gene id: 1074467:JP39_RS01875
uniprot id: A0A0K2LA98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1074467:JP39 RS01580
gene id: 1074467:JP39_RS01580
uniprot id: A0A0K2LA47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS02725
gene id: 1074467:JP39_RS02725
uniprot id: A0A0K2LAR7
names: Similarity
messages: Belongs to the thioredoxin family.

1074467:JP39 RS05690
gene id: 1074467:JP39_RS05690
uniprot id: A0A0K2LC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02675
gene id: 1074467:JP39_RS02675
uniprot id: A0A0K2LAQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05955
gene id: 1074467:JP39_RS05955
uniprot id: A0A0K2LCE7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1074467:JP39 RS02475
gene id: 1074467:JP39_RS02475
uniprot id: A0A0K2LAW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1074467:JP39 RS06695
gene id: 1074467:JP39_RS06695
uniprot id: A0A0K2LCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1074467:JP39 RS03725
gene id: 1074467:JP39_RS03725
uniprot id: A0A0K2LBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1074467:JP39 RS04585
gene id: 1074467:JP39_RS04585
uniprot id: A0A0K2LBK9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1074467:JP39 RS01845
gene id: 1074467:JP39_RS01845
uniprot id: A0A0K2LAK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1074467:JP39 RS07580
gene id: 1074467:JP39_RS07580
uniprot id: A0A0K2LD54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1074467:JP39 RS12065
gene id: 1074467:JP39_RS12065
uniprot id: A0A0K2LFF7
names: Similarity
messages: Belongs to the UPF0246 family.

1074467:JP39 RS03895
gene id: 1074467:JP39_RS03895
uniprot id: A0A0K2LBD9
names: Similarity
messages: Belongs to the FGGY kinase family.

1074467:JP39 RS07700
gene id: 1074467:JP39_RS07700
uniprot id: A0A0K2LD77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1074467:JP39 RS05560
gene id: 1074467:JP39_RS05560
uniprot id: A0A0K2LC77
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1074467:JP39 RS06660
gene id: 1074467:JP39_RS06660
uniprot id: A0A0K2LCP9
names: Similarity
messages: Belongs to the GARS family.

1074467:JP39 RS05125
gene id: 1074467:JP39_RS05125
uniprot id: A0A0K2LBW0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08405
gene id: 1074467:JP39_RS08405
uniprot id: A0A0K2LDJ6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1074467:JP39 RS07695
gene id: 1074467:JP39_RS07695
uniprot id: A0A0K2LDB3
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1074467:JP39 RS00180
gene id: 1074467:JP39_RS00180
uniprot id: A0A0K2L9P1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1074467:JP39 RS09935
gene id: 1074467:JP39_RS09935
uniprot id: A0A0K2LEP1
names: Similarity
messages: Belongs to the EamA transporter family.

1074467:JP39 RS05740
gene id: 1074467:JP39_RS05740
uniprot id: A0A0K2LFS8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1074467:JP39 RS01980
gene id: 1074467:JP39_RS01980
uniprot id: A0A0K2LAB9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS08810
gene id: 1074467:JP39_RS08810
uniprot id: A0A0K2LDS2
names: Similarity
messages: Belongs to the acetyltransferase family.

1074467:JP39 RS12000
gene id: 1074467:JP39_RS12000
uniprot id: A0A0K2LG00
names: Similarity
messages: Belongs to the ThiD family.

1074467:JP39 RS06600
gene id: 1074467:JP39_RS06600
uniprot id: A0A0K2LCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1074467:JP39 RS08850
gene id: 1074467:JP39_RS08850
uniprot id: A0A0K2LDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04465
gene id: 1074467:JP39_RS04465
uniprot id: A0A0K2LBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1074467:JP39 RS03860
gene id: 1074467:JP39_RS03860
uniprot id: A0A0K2LBL0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1074467:JP39 RS06165
gene id: 1074467:JP39_RS06165
uniprot id: A0A0K2LCE9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1074467:JP39 RS10885
gene id: 1074467:JP39_RS10885
uniprot id: A0A0K2LF55
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS05835
gene id: 1074467:JP39_RS05835
uniprot id: A0A0K2LC91
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1074467:JP39 RS10840
gene id: 1074467:JP39_RS10840
uniprot id: A0A0K2LET4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1074467:JP39 RS01890
gene id: 1074467:JP39_RS01890
uniprot id: A0A0K2LA90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1074467:JP39 RS09370
gene id: 1074467:JP39_RS09370
uniprot id: A0A0K2LE17
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1074467:JP39 RS11875
gene id: 1074467:JP39_RS11875
uniprot id: A0A0K2LFC9
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS01665
gene id: 1074467:JP39_RS01665
uniprot id: A0A0K2LA99
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1074467:JP39 RS08200
gene id: 1074467:JP39_RS08200
uniprot id: A0A0K2LDF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS04490
gene id: 1074467:JP39_RS04490
uniprot id: A0A0K2LBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1074467:JP39 RS02460
gene id: 1074467:JP39_RS02460
uniprot id: A0A0K2LAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1074467:JP39 RS06730
gene id: 1074467:JP39_RS06730
uniprot id: A0A0K2LD31
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1074467:JP39 RS04615
gene id: 1074467:JP39_RS04615
uniprot id: A0A0K2LBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1074467:JP39 RS03500
gene id: 1074467:JP39_RS03500
uniprot id: A0A0K2LFT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS08955
gene id: 1074467:JP39_RS08955
uniprot id: A0A0K2LE49
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1074467:JP39 RS05995
gene id: 1074467:JP39_RS05995
uniprot id: A0A0K2LCB8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03520
gene id: 1074467:JP39_RS03520
uniprot id: A0A0K2LBB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1074467:JP39 RS11800
gene id: 1074467:JP39_RS11800
uniprot id: A0A0K2LFA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1074467:JP39 RS07270
gene id: 1074467:JP39_RS07270
uniprot id: A0A0K2LDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1074467:JP39 RS06590
gene id: 1074467:JP39_RS06590
uniprot id: A0A0K2LCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1074467:JP39 RS05915
gene id: 1074467:JP39_RS05915
uniprot id: A0A0K2LCM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1074467:JP39 RS10385
gene id: 1074467:JP39_RS10385
uniprot id: A0A0K2LEN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS00390
gene id: 1074467:JP39_RS00390
uniprot id: A0A0K2L9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1074467:JP39 RS06570
gene id: 1074467:JP39_RS06570
uniprot id: A0A0K2LCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1074467:JP39 RS00030
gene id: 1074467:JP39_RS00030
uniprot id: A0A0K2L9C0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00600
gene id: 1074467:JP39_RS00600
uniprot id: A0A0K2L9L3
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS04975
gene id: 1074467:JP39_RS04975
uniprot id: A0A0K2LBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1074467:JP39 RS08175
gene id: 1074467:JP39_RS08175
uniprot id: A0A0K2LDS3
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1074467:JP39 RS10235
gene id: 1074467:JP39_RS10235
uniprot id: A0A0K2LEK5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS12240
gene id: 1074467:JP39_RS12240
uniprot id: A0A0K2LFJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03775
gene id: 1074467:JP39_RS03775
uniprot id: A0A0K2LBH2
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1074467:JP39 RS02250
gene id: 1074467:JP39_RS02250
uniprot id: A0A0K2LAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05845
gene id: 1074467:JP39_RS05845
uniprot id: A0A0K2LC94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS07000
gene id: 1074467:JP39_RS07000
uniprot id: A0A0K2LCV9
names: Similarity
messages: Belongs to the TlyA family.

1074467:JP39 RS02320
gene id: 1074467:JP39_RS02320
uniprot id: A0A0K2LAI3
names: Similarity
messages: Belongs to the UPF0177 family.

1074467:JP39 RS09350
gene id: 1074467:JP39_RS09350
uniprot id: A0A0K2LE35
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1074467:JP39 RS05440
gene id: 1074467:JP39_RS05440
uniprot id: A0A0K2LCE0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1074467:JP39 RS09830
gene id: 1074467:JP39_RS09830
uniprot id: A0A0K2LEA2
names: Similarity
messages: Belongs to the TPP enzyme family.

1074467:JP39 RS00605
gene id: 1074467:JP39_RS00605
uniprot id: A0A0K2L9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1074467:JP39 RS09380
gene id: 1074467:JP39_RS09380
uniprot id: A0A0K2LE20
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1074467:JP39 RS01590
gene id: 1074467:JP39_RS01590
uniprot id: A0A0K2LA56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1074467:JP39 RS05635
gene id: 1074467:JP39_RS05635
uniprot id: A0A0K2LCH5
names: Similarity
messages: Belongs to the LOG family.

1074467:JP39 RS06595
gene id: 1074467:JP39_RS06595
uniprot id: A0A0K2LCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1074467:JP39 RS02810
gene id: 1074467:JP39_RS02810
uniprot id: A0A0K2LB33
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1074467:JP39 RS11005
gene id: 1074467:JP39_RS11005
uniprot id: A0A0K2LEW4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1074467:JP39 RS10420
gene id: 1074467:JP39_RS10420
uniprot id: A0A0K2LEJ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1074467:JP39 RS04565
gene id: 1074467:JP39_RS04565
uniprot id: A0A0K2LBK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1074467:JP39 RS02030
gene id: 1074467:JP39_RS02030
uniprot id: A0A0K2LAC9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS07030
gene id: 1074467:JP39_RS07030
uniprot id: A0A0K2LCZ9
names: Similarity
messages: Belongs to the asp23 family.

1074467:JP39 RS01615
gene id: 1074467:JP39_RS01615
uniprot id: A0A0K2LA61
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1074467:JP39 RS04200
gene id: 1074467:JP39_RS04200
uniprot id: A0A0K2LBE8
names: Similarity
messages: Belongs to the UPF0145 family.

1074467:JP39 RS01945
gene id: 1074467:JP39_RS01945
uniprot id: A0A0K2LAA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1074467:JP39 RS05985
gene id: 1074467:JP39_RS05985
uniprot id: A0A0K2LCF1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1074467:JP39 RS09945
gene id: 1074467:JP39_RS09945
uniprot id: A0A0K2LEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04455
gene id: 1074467:JP39_RS04455
uniprot id: A0A0K2LBM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1074467:JP39 RS04425
gene id: 1074467:JP39_RS04425
uniprot id: A0A0K2LBM1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1074467:JP39 RS06300
gene id: 1074467:JP39_RS06300
uniprot id: A0A0K2LCH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS06575
gene id: 1074467:JP39_RS06575
uniprot id: A0A0K2LCY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1074467:JP39 RS04030
gene id: 1074467:JP39_RS04030
uniprot id: A0A0K2LBB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1074467:JP39 RS02105
gene id: 1074467:JP39_RS02105
uniprot id: A0A0K2LAE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1074467:JP39 RS01825
gene id: 1074467:JP39_RS01825
uniprot id: A0A0K2LA87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1074467:JP39 RS02735
gene id: 1074467:JP39_RS02735
uniprot id: A0A0K2LB18
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1074467:JP39 RS06865
gene id: 1074467:JP39_RS06865
uniprot id: A0A0K2LCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1074467:JP39 RS06930
gene id: 1074467:JP39_RS06930
uniprot id: A0A0K2LCU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1074467:JP39 RS11260
gene id: 1074467:JP39_RS11260
uniprot id: A0A0K2LF08
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1074467:JP39 RS09085
gene id: 1074467:JP39_RS09085
uniprot id: A0A0K2LDX0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1074467:JP39 RS01635
gene id: 1074467:JP39_RS01635
uniprot id: A0A0K2LA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1074467:JP39 RS08575
gene id: 1074467:JP39_RS08575
uniprot id: A0A0K2LDR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1074467:JP39 RS06625
gene id: 1074467:JP39_RS06625
uniprot id: A0A0K2LCP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1074467:JP39 RS03180
gene id: 1074467:JP39_RS03180
uniprot id: A0A0K2LAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1074467:JP39 RS07765
gene id: 1074467:JP39_RS07765
uniprot id: A0A0K2LD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06845
gene id: 1074467:JP39_RS06845
uniprot id: A0A0K2LCT1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS01905
gene id: 1074467:JP39_RS01905
uniprot id: A0A0K2LAD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1074467:JP39 RS07145
gene id: 1074467:JP39_RS07145
uniprot id: A0A0K2LDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05815
gene id: 1074467:JP39_RS05815
uniprot id: A0A0K2LC89
names: Caution
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS01700
gene id: 1074467:JP39_RS01700
uniprot id: A0A0K2LAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1074467:JP39 RS02440
gene id: 1074467:JP39_RS02440
uniprot id: A0A0K2LAL3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1074467:JP39 RS05135
gene id: 1074467:JP39_RS05135
uniprot id: A0A0K2LFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1074467:JP39 RS05040
gene id: 1074467:JP39_RS05040
uniprot id: A0A0K2LBU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS10400
gene id: 1074467:JP39_RS10400
uniprot id: A0A0K2LEL1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1074467:JP39 RS06710
gene id: 1074467:JP39_RS06710
uniprot id: A0A0K2LCQ8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1074467:JP39 RS11560
gene id: 1074467:JP39_RS11560
uniprot id: A0A0K2LFH8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1074467:JP39 RS11795
gene id: 1074467:JP39_RS11795
uniprot id: A0A0K2LFD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1074467:JP39 RS05930
gene id: 1074467:JP39_RS05930
uniprot id: A0A0K2LCE1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1074467:JP39 RS01985
gene id: 1074467:JP39_RS01985
uniprot id: A0A0K2LAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1074467:JP39 RS02285
gene id: 1074467:JP39_RS02285
uniprot id: A0A0K2LAG6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1074467:JP39 RS01975
gene id: 1074467:JP39_RS01975
uniprot id: A0A0K2LAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1074467:JP39 RS04640
gene id: 1074467:JP39_RS04640
uniprot id: A0A0K2LFS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS06675
gene id: 1074467:JP39_RS06675
uniprot id: A0A0K2LCQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1074467:JP39 RS12215
gene id: 1074467:JP39_RS12215
uniprot id: A0A0K2LFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS09480
gene id: 1074467:JP39_RS09480
uniprot id: A0A0K2LE78
names: Similarity
messages: Belongs to the TPP enzyme family.

1074467:JP39 RS08865
gene id: 1074467:JP39_RS08865
uniprot id: A0A0K2LE36
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1074467:JP39 RS11610
gene id: 1074467:JP39_RS11610
uniprot id: A0A0K2LFI4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1074467:JP39 RS01415
gene id: 1074467:JP39_RS01415
uniprot id: A0A0K2LA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06700
gene id: 1074467:JP39_RS06700
uniprot id: A0A0K2LCQ7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1074467:JP39 RS06105
gene id: 1074467:JP39_RS06105
uniprot id: A0A0K2LCP2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1074467:JP39 RS04230
gene id: 1074467:JP39_RS04230
uniprot id: A0A0K2LBE7
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11780
gene id: 1074467:JP39_RS11780
uniprot id: A0A0K2LFB4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1074467:JP39 RS06540
gene id: 1074467:JP39_RS06540
uniprot id: A0A0K2LCM1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1074467:JP39 RS11095
gene id: 1074467:JP39_RS11095
uniprot id: A0A0K2LEX8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06935
gene id: 1074467:JP39_RS06935
uniprot id: A0A0K2LCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1074467:JP39 RS04730
gene id: 1074467:JP39_RS04730
uniprot id: A0A0K2LC11
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1074467:JP39 RS02520
gene id: 1074467:JP39_RS02520
uniprot id: A0A0K2LAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1074467:JP39 RS07795
gene id: 1074467:JP39_RS07795
uniprot id: A0A0K2LD87
names: Subcellular Location Annotation
messages: cell wall

1074467:JP39 RS00475
gene id: 1074467:JP39_RS00475
uniprot id: A0A0K2L9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00865
gene id: 1074467:JP39_RS00865
uniprot id: A0A0K2LA09
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS04700
gene id: 1074467:JP39_RS04700
uniprot id: A0A0K2LC05
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1074467:JP39 RS07770
gene id: 1074467:JP39_RS07770
uniprot id: A0A0K2LD79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06680
gene id: 1074467:JP39_RS06680
uniprot id: A0A0K2LD22
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS07915
gene id: 1074467:JP39_RS07915
uniprot id: A0A0K2LDN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS07125
gene id: 1074467:JP39_RS07125
uniprot id: A0A0K2LCY1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1074467:JP39 RS08650
gene id: 1074467:JP39_RS08650
uniprot id: A0A0K2LDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1074467:JP39 RS06890
gene id: 1074467:JP39_RS06890
uniprot id: A0A0K2LCT9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1074467:JP39 RS03835
gene id: 1074467:JP39_RS03835
uniprot id: A0A0K2LBK5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1074467:JP39 RS00170
gene id: 1074467:JP39_RS00170
uniprot id: A0A0K2L9F3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1074467:JP39 RS05480
gene id: 1074467:JP39_RS05480
uniprot id: A0A0K2LC62
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

1074467:JP39 RS10165
gene id: 1074467:JP39_RS10165
uniprot id: A0A0K2LEG5
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS06880
gene id: 1074467:JP39_RS06880
uniprot id: A0A0K2LCT8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1074467:JP39 RS06295
gene id: 1074467:JP39_RS06295
uniprot id: A0A0K2LCK7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1074467:JP39 RS11160
gene id: 1074467:JP39_RS11160
uniprot id: A0A0K2LEZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04555
gene id: 1074467:JP39_RS04555
uniprot id: A0A0K2LBK8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS09000
gene id: 1074467:JP39_RS09000
uniprot id: A0A0K2LDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1074467:JP39 RS09080
gene id: 1074467:JP39_RS09080
uniprot id: A0A0K2LE00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1074467:JP39 RS05750
gene id: 1074467:JP39_RS05750
uniprot id: A0A0K2LC75
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1074467:JP39 RS07445
gene id: 1074467:JP39_RS07445
uniprot id: A0A0K2LD37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1074467:JP39 RS01245
gene id: 1074467:JP39_RS01245
uniprot id: A0A0K2LAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1074467:JP39 RS04920
gene id: 1074467:JP39_RS04920
uniprot id: A0A0K2LBS8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1074467:JP39 RS02585
gene id: 1074467:JP39_RS02585
uniprot id: A0A0K2LAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1074467:JP39 RS04295
gene id: 1074467:JP39_RS04295
uniprot id: A0A0K2LBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1074467:JP39 RS04715
gene id: 1074467:JP39_RS04715
uniprot id: A0A0K2LBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1074467:JP39 RS07310
gene id: 1074467:JP39_RS07310
uniprot id: A0A0K2LD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1074467:JP39 RS07690
gene id: 1074467:JP39_RS07690
uniprot id: A0A0K2LD76
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1074467:JP39 RS10350
gene id: 1074467:JP39_RS10350
uniprot id: A0A0K2LEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1074467:JP39 RS06000
gene id: 1074467:JP39_RS06000
uniprot id: A0A0K2LCN1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1074467:JP39 RS11545
gene id: 1074467:JP39_RS11545
uniprot id: A0A0K2LF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS10105
gene id: 1074467:JP39_RS10105
uniprot id: A0A0K2LEF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00120
gene id: 1074467:JP39_RS00120
uniprot id: A0A0K2L9E5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07550
gene id: 1074467:JP39_RS07550
uniprot id: A0A0K2LD50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1074467:JP39 RS07180
gene id: 1074467:JP39_RS07180
uniprot id: A0A0K2LD23
names: Similarity
messages: Belongs to the acylphosphatase family.

1074467:JP39 RS09855
gene id: 1074467:JP39_RS09855
uniprot id: A0A0K2LEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03620
gene id: 1074467:JP39_RS03620
uniprot id: A0A0K2LB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00855
gene id: 1074467:JP39_RS00855
uniprot id: A0A0K2L9S6
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS01960
gene id: 1074467:JP39_RS01960
uniprot id: A0A0K2LAE7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1074467:JP39 RS10340
gene id: 1074467:JP39_RS10340
uniprot id: A0A0K2LEI2
names: Similarity
messages: Belongs to the SecB family.

1074467:JP39 RS07515
gene id: 1074467:JP39_RS07515
uniprot id: A0A0K2LD44
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1074467:JP39 RS11205
gene id: 1074467:JP39_RS11205
uniprot id: A0A0K2LF27
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1074467:JP39 RS10135
gene id: 1074467:JP39_RS10135
uniprot id: A0A0K2LES6
names: Similarity
messages: Belongs to the peptidase C59 family.

1074467:JP39 RS01685
gene id: 1074467:JP39_RS01685
uniprot id: A0A0K2LAH9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS00810
gene id: 1074467:JP39_RS00810
uniprot id: A0A0K2L9Q2
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1074467:JP39 RS11745
gene id: 1074467:JP39_RS11745
uniprot id: A0A0K2LFC6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1074467:JP39 RS11570
gene id: 1074467:JP39_RS11570
uniprot id: A0A0K2LF95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02155
gene id: 1074467:JP39_RS02155
uniprot id: A0A0K2LAF4
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07980
gene id: 1074467:JP39_RS07980
uniprot id: A0A0K2LDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1074467:JP39 RS05590
gene id: 1074467:JP39_RS05590
uniprot id: A0A0K2LC49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1074467:JP39 RS02345
gene id: 1074467:JP39_RS02345
uniprot id: A0A0K2LAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06565
gene id: 1074467:JP39_RS06565
uniprot id: A0A0K2LCM6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1074467:JP39 RS04545
gene id: 1074467:JP39_RS04545
uniprot id: A0A0K2LBX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1074467:JP39 RS04850
gene id: 1074467:JP39_RS04850
uniprot id: A0A0K2LBR1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS04435
gene id: 1074467:JP39_RS04435
uniprot id: A0A0K2LBI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1074467:JP39 RS03875
gene id: 1074467:JP39_RS03875
uniprot id: A0A0K2LBA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS11115
gene id: 1074467:JP39_RS11115
uniprot id: A0A0K2LF96
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1074467:JP39 RS09420
gene id: 1074467:JP39_RS09420
uniprot id: A0A0K2LED1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06815
gene id: 1074467:JP39_RS06815
uniprot id: A0A0K2LCW6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00545
gene id: 1074467:JP39_RS00545
uniprot id: A0A0K2L9U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03910
gene id: 1074467:JP39_RS03910
uniprot id: A0A0K2LBA0
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS07290
gene id: 1074467:JP39_RS07290
uniprot id: A0A0K2LD04
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS07390
gene id: 1074467:JP39_RS07390
uniprot id: A0A0K2LD26
names: Similarity
messages: Belongs to the universal stress protein A family.

1074467:JP39 RS02180
gene id: 1074467:JP39_RS02180
uniprot id: A0A0K2LAF9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1074467:JP39 RS02140
gene id: 1074467:JP39_RS02140
uniprot id: A0A0K2LAF7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1074467:JP39 RS02115
gene id: 1074467:JP39_RS02115
uniprot id: A0A0K2LAF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS02600
gene id: 1074467:JP39_RS02600
uniprot id: A0A0K2LAM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1074467:JP39 RS08465
gene id: 1074467:JP39_RS08465
uniprot id: A0A0K2LDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1074467:JP39 RS08510
gene id: 1074467:JP39_RS08510
uniprot id: A0A0K2LDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1074467:JP39 RS03675
gene id: 1074467:JP39_RS03675
uniprot id: A0A0K2LB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08925
gene id: 1074467:JP39_RS08925
uniprot id: A0A0K2LDU3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1074467:JP39 RS03300
gene id: 1074467:JP39_RS03300
uniprot id: A0A0K2LAZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS10600
gene id: 1074467:JP39_RS10600
uniprot id: A0A0K2LER7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1074467:JP39 RS11790
gene id: 1074467:JP39_RS11790
uniprot id: A0A0K2LFA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1074467:JP39 RS00995
gene id: 1074467:JP39_RS00995
uniprot id: A0A0K2LA58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

1074467:JP39 RS02720
gene id: 1074467:JP39_RS02720
uniprot id: A0A0K2LAU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1074467:JP39 RS09375
gene id: 1074467:JP39_RS09375
uniprot id: A0A0K2LE39
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS01640
gene id: 1074467:JP39_RS01640
uniprot id: A0A0K2LA66
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1074467:JP39 RS02170
gene id: 1074467:JP39_RS02170
uniprot id: A0A0K2LAE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05935
gene id: 1074467:JP39_RS05935
uniprot id: A0A0K2LCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1074467:JP39 RS12020
gene id: 1074467:JP39_RS12020
uniprot id: A0A0K2LFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1074467:JP39 RS05735
gene id: 1074467:JP39_RS05735
uniprot id: A0A0K2LC73
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1074467:JP39 RS09820
gene id: 1074467:JP39_RS09820
uniprot id: A0A0K2LEB0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS00880
gene id: 1074467:JP39_RS00880
uniprot id: A0A0K2L9T0
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1074467:JP39 RS11080
gene id: 1074467:JP39_RS11080
uniprot id: A0A0K2LEX1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1074467:JP39 RS04890
gene id: 1074467:JP39_RS04890
uniprot id: A0A0K2LC40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1074467:JP39 RS03025
gene id: 1074467:JP39_RS03025
uniprot id: A0A0K2LAX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS08120
gene id: 1074467:JP39_RS08120
uniprot id: A0A0K2LDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1074467:JP39 RS04940
gene id: 1074467:JP39_RS04940
uniprot id: A0A0K2LC50
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1074467:JP39 RS00480
gene id: 1074467:JP39_RS00480
uniprot id: A0A0K2L9M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1074467:JP39 RS05465
gene id: 1074467:JP39_RS05465
uniprot id: A0A0K2LC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00400
gene id: 1074467:JP39_RS00400
uniprot id: A0A0K2L9S9
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00860
gene id: 1074467:JP39_RS00860
uniprot id: A0A0K2L9R2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07360
gene id: 1074467:JP39_RS07360
uniprot id: A0A0K2LD58
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1074467:JP39 RS02450
gene id: 1074467:JP39_RS02450
uniprot id: A0A0K2LAW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1074467:JP39 RS10180
gene id: 1074467:JP39_RS10180
uniprot id: A0A0K2LEJ5
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS09125
gene id: 1074467:JP39_RS09125
uniprot id: A0A0K2LDX8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS10275
gene id: 1074467:JP39_RS10275
uniprot id: A0A0K2LEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11955
gene id: 1074467:JP39_RS11955
uniprot id: A0A0K2LFN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1074467:JP39 RS09910
gene id: 1074467:JP39_RS09910
uniprot id: A0A0K2LEB7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS08060
gene id: 1074467:JP39_RS08060
uniprot id: A0A0K2LDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1074467:JP39 RS11025
gene id: 1074467:JP39_RS11025
uniprot id: A0A0K2LEZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1074467:JP39 RS02400
gene id: 1074467:JP39_RS02400
uniprot id: A0A0K2LG06
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1074467:JP39 RS03680
gene id: 1074467:JP39_RS03680
uniprot id: A0A0K2LFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02255
gene id: 1074467:JP39_RS02255
uniprot id: A0A0K2LAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1074467:JP39 RS07895
gene id: 1074467:JP39_RS07895
uniprot id: A0A0K2LDA5
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

1074467:JP39 RS01285
gene id: 1074467:JP39_RS01285
uniprot id: A0A0K2LA07
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1074467:JP39 RS08940
gene id: 1074467:JP39_RS08940
uniprot id: A0A0K2LDX7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1074467:JP39 RS08700
gene id: 1074467:JP39_RS08700
uniprot id: A0A0K2LE13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1074467:JP39 RS06545
gene id: 1074467:JP39_RS06545
uniprot id: A0A0K2LCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1074467:JP39 RS08240
gene id: 1074467:JP39_RS08240
uniprot id: A0A0K2LDK3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1074467:JP39 RS00685
gene id: 1074467:JP39_RS00685
uniprot id: A0A0K2L9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1074467:JP39 RS07155
gene id: 1074467:JP39_RS07155
uniprot id: A0A0K2LD18
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1074467:JP39 RS02290
gene id: 1074467:JP39_RS02290
uniprot id: A0A0K2LAT5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05595
gene id: 1074467:JP39_RS05595
uniprot id: A0A0K2LFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1074467:JP39 RS12140
gene id: 1074467:JP39_RS12140
uniprot id: A0A0K2LFS7
names: Subcellular Location Annotation
messages: Cell membrane

1074467:JP39 RS07105
gene id: 1074467:JP39_RS07105
uniprot id: A0A0K2LCX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS01735
gene id: 1074467:JP39_RS01735
uniprot id: A0A0K2LA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1074467:JP39 RS06010
gene id: 1074467:JP39_RS06010
uniprot id: A0A0K2LCF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS06335
gene id: 1074467:JP39_RS06335
uniprot id: A0A0K2LCT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS03095
gene id: 1074467:JP39_RS03095
uniprot id: A0A0K2LB58
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1074467:JP39 RS11085
gene id: 1074467:JP39_RS11085
uniprot id: A0A0K2LEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1074467:JP39 RS00065
gene id: 1074467:JP39_RS00065
uniprot id: A0A0K2L9D5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1074467:JP39 RS07610
gene id: 1074467:JP39_RS07610
uniprot id: A0A0K2LD62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1074467:JP39 RS10065
gene id: 1074467:JP39_RS10065
uniprot id: A0A0K2LEE0
names: Similarity
messages: Belongs to the universal stress protein A family.

1074467:JP39 RS06855
gene id: 1074467:JP39_RS06855
uniprot id: A0A0K2LCT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1074467:JP39 RS05945
gene id: 1074467:JP39_RS05945
uniprot id: A0A0K2LCM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1074467:JP39 RS02665
gene id: 1074467:JP39_RS02665
uniprot id: A0A0K2LFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1074467:JP39 RS10720
gene id: 1074467:JP39_RS10720
uniprot id: A0A0K2LET7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1074467:JP39 RS06530
gene id: 1074467:JP39_RS06530
uniprot id: A0A0K2LCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1074467:JP39 RS10545
gene id: 1074467:JP39_RS10545
uniprot id: A0A0K2LEQ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS07975
gene id: 1074467:JP39_RS07975
uniprot id: A0A0K2LDF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02700
gene id: 1074467:JP39_RS02700
uniprot id: A0A0K2LAR2
names: Similarity
messages: Belongs to the UPF0297 family.

1074467:JP39 RS11225
gene id: 1074467:JP39_RS11225
uniprot id: A0A0K2LF04
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1074467:JP39 RS03480
gene id: 1074467:JP39_RS03480
uniprot id: A0A0K2LB25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS08470
gene id: 1074467:JP39_RS08470
uniprot id: A0A0K2LDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1074467:JP39 RS01935
gene id: 1074467:JP39_RS01935
uniprot id: A0A0K2LAE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1074467:JP39 RS03070
gene id: 1074467:JP39_RS03070
uniprot id: A0A0K2LB53
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS04780
gene id: 1074467:JP39_RS04780
uniprot id: A0A0K2LBP2
names: Similarity
messages: Belongs to the PemK/MazF family.

1074467:JP39 RS08085
gene id: 1074467:JP39_RS08085
uniprot id: A0A0K2LDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1074467:JP39 RS04800
gene id: 1074467:JP39_RS04800
uniprot id: A0A0K2LBQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1074467:JP39 RS07960
gene id: 1074467:JP39_RS07960
uniprot id: A0A0K2LDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1074467:JP39 RS01065
gene id: 1074467:JP39_RS01065
uniprot id: A0A0K2L9X2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1074467:JP39 RS03400
gene id: 1074467:JP39_RS03400
uniprot id: A0A0K2LAZ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS03090
gene id: 1074467:JP39_RS03090
uniprot id: A0A0K2LAU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1074467:JP39 RS11625
gene id: 1074467:JP39_RS11625
uniprot id: A0A0K2LFA6
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1074467:JP39 RS02110
gene id: 1074467:JP39_RS02110
uniprot id: A0A0K2LAH7
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05080
gene id: 1074467:JP39_RS05080
uniprot id: A0A0K2LC76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1074467:JP39 RS02015
gene id: 1074467:JP39_RS02015
uniprot id: A0A0K2LAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03555
gene id: 1074467:JP39_RS03555
uniprot id: A0A0K2LB42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS00040
gene id: 1074467:JP39_RS00040
uniprot id: A0A0K2LFL0
names: Subcellular Location Annotation
messages: cell wall

1074467:JP39 RS03760
gene id: 1074467:JP39_RS03760
uniprot id: A0A0K2LB89
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1074467:JP39 RS05660
gene id: 1074467:JP39_RS05660
uniprot id: A0A0K2LCI0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1074467:JP39 RS01970
gene id: 1074467:JP39_RS01970
uniprot id: A0A0K2LAA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS05530
gene id: 1074467:JP39_RS05530
uniprot id: A0A0K2LC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1074467:JP39 RS10250
gene id: 1074467:JP39_RS10250
uniprot id: A0A0K2LEU6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1074467:JP39 RS04570
gene id: 1074467:JP39_RS04570
uniprot id: A0A0K2LBY1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1074467:JP39 RS02550
gene id: 1074467:JP39_RS02550
uniprot id: A0A0K2LAY4
names: Similarity
messages: Belongs to the UPF0237 family.

1074467:JP39 RS00735
gene id: 1074467:JP39_RS00735
uniprot id: A0A0K2L9X5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1074467:JP39 RS06840
gene id: 1074467:JP39_RS06840
uniprot id: A0A0K2LCX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1074467:JP39 RS00140
gene id: 1074467:JP39_RS00140
uniprot id: A0A0K2L9G7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1074467:JP39 RS12125
gene id: 1074467:JP39_RS12125
uniprot id: A0A0K2LFI7
names: Similarity
messages: Belongs to the ParB family.

1074467:JP39 RS12190
gene id: 1074467:JP39_RS12190
uniprot id: A0A0K2LFJ7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS00740
gene id: 1074467:JP39_RS00740
uniprot id: A0A0K2L9P8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS03465
gene id: 1074467:JP39_RS03465
uniprot id: A0A0K2LB27
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11525
gene id: 1074467:JP39_RS11525
uniprot id: A0A0K2LF58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02710
gene id: 1074467:JP39_RS02710
uniprot id: A0A0K2LB13
names: Similarity
messages: Belongs to the UPF0473 family.

1074467:JP39 RS05155
gene id: 1074467:JP39_RS05155
uniprot id: A0A0K2LBW5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1074467:JP39 RS03100
gene id: 1074467:JP39_RS03100
uniprot id: A0A0K2LAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1074467:JP39 RS02555
gene id: 1074467:JP39_RS02555
uniprot id: A0A0K2LAN6
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1074467:JP39 RS06870
gene id: 1074467:JP39_RS06870
uniprot id: A0A0K2LCX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1074467:JP39 RS07050
gene id: 1074467:JP39_RS07050
uniprot id: A0A0K2LCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1074467:JP39 RS07010
gene id: 1074467:JP39_RS07010
uniprot id: A0A0K2LCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1074467:JP39 RS11255
gene id: 1074467:JP39_RS11255
uniprot id: A0A0K2LF37
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1074467:JP39 RS03060
gene id: 1074467:JP39_RS03060
uniprot id: A0A0K2LAV2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1074467:JP39 RS11680
gene id: 1074467:JP39_RS11680
uniprot id: A0A0K2LF87
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS04430
gene id: 1074467:JP39_RS04430
uniprot id: A0A0K2LBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1074467:JP39 RS10875
gene id: 1074467:JP39_RS10875
uniprot id: A0A0K2LET3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS07855
gene id: 1074467:JP39_RS07855
uniprot id: A0A0K2LDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1074467:JP39 RS05555
gene id: 1074467:JP39_RS05555
uniprot id: A0A0K2LC41
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

1074467:JP39 RS01165
gene id: 1074467:JP39_RS01165
uniprot id: A0A0K2LA88
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11375
gene id: 1074467:JP39_RS11375
uniprot id: A0A0K2LFE4
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS03040
gene id: 1074467:JP39_RS03040
uniprot id: A0A0K2LB48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1074467:JP39 RS04170
gene id: 1074467:JP39_RS04170
uniprot id: A0A0K2LBD7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1074467:JP39 RS04915
gene id: 1074467:JP39_RS04915
uniprot id: A0A0K2LC45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1074467:JP39 RS05665
gene id: 1074467:JP39_RS05665
uniprot id: A0A0K2LC60
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1074467:JP39 RS09880
gene id: 1074467:JP39_RS09880
uniprot id: A0A0K2LEB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1074467:JP39 RS06455
gene id: 1074467:JP39_RS06455
uniprot id: A0A0K2LCN2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11400
gene id: 1074467:JP39_RS11400
uniprot id: A0A0K2LF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS10070
gene id: 1074467:JP39_RS10070
uniprot id: A0A0K2LEH5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1074467:JP39 RS04400
gene id: 1074467:JP39_RS04400
uniprot id: A0A0K2LBH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1074467:JP39 RS06745
gene id: 1074467:JP39_RS06745
uniprot id: A0A0K2LCR3
names: Similarity
messages: Belongs to the peptidase C40 family.

1074467:JP39 RS01995
gene id: 1074467:JP39_RS01995
uniprot id: A0A0K2LAB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1074467:JP39 RS07680
gene id: 1074467:JP39_RS07680
uniprot id: A0A0K2LD71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1074467:JP39 RS02135
gene id: 1074467:JP39_RS02135
uniprot id: A0A0K2LAI2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1074467:JP39 RS12030
gene id: 1074467:JP39_RS12030
uniprot id: A0A0K2LFF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1074467:JP39 RS03585
gene id: 1074467:JP39_RS03585
uniprot id: A0A0K2LB71
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS04655
gene id: 1074467:JP39_RS04655
uniprot id: A0A0K2LBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1074467:JP39 RS05960
gene id: 1074467:JP39_RS05960
uniprot id: A0A0K2LCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1074467:JP39 RS01190
gene id: 1074467:JP39_RS01190
uniprot id: A0A0K2L9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01915
gene id: 1074467:JP39_RS01915
uniprot id: A0A0K2LA95
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1074467:JP39 RS06415
gene id: 1074467:JP39_RS06415
uniprot id: A0A0K2LCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1074467:JP39 RS01440
gene id: 1074467:JP39_RS01440
uniprot id: A0A0K2LA34
names: Similarity
messages: Belongs to the DtxR/MntR family.

1074467:JP39 RS10535
gene id: 1074467:JP39_RS10535
uniprot id: A0A0K2LEZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1074467:JP39 RS04330
gene id: 1074467:JP39_RS04330
uniprot id: A0A0K2LBH0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1074467:JP39 RS03830
gene id: 1074467:JP39_RS03830
uniprot id: A0A0K2LB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1074467:JP39 RS11825
gene id: 1074467:JP39_RS11825
uniprot id: A0A0K2LFE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1074467:JP39 RS06670
gene id: 1074467:JP39_RS06670
uniprot id: A0A0K2LCQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS04205
gene id: 1074467:JP39_RS04205
uniprot id: A0A0K2LBE2
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS02020
gene id: 1074467:JP39_RS02020
uniprot id: A0A0K2LAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1074467:JP39 RS08675
gene id: 1074467:JP39_RS08675
uniprot id: A0A0K2LE08
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07325
gene id: 1074467:JP39_RS07325
uniprot id: A0A0K2LDD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02080
gene id: 1074467:JP39_RS02080
uniprot id: A0A0K2LAD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1074467:JP39 RS01705
gene id: 1074467:JP39_RS01705
uniprot id: A0A0K2LA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1074467:JP39 RS03440
gene id: 1074467:JP39_RS03440
uniprot id: A0A0K2LB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1074467:JP39 RS09325
gene id: 1074467:JP39_RS09325
uniprot id: A0A0K2LE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04245
gene id: 1074467:JP39_RS04245
uniprot id: A0A0K2LBJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1074467:JP39 RS05920
gene id: 1074467:JP39_RS05920
uniprot id: A0A0K2LCA7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1074467:JP39 RS06980
gene id: 1074467:JP39_RS06980
uniprot id: A0A0K2LCZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1074467:JP39 RS10230
gene id: 1074467:JP39_RS10230
uniprot id: A0A0K2LEH2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08965
gene id: 1074467:JP39_RS08965
uniprot id: A0A0K2LDU7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1074467:JP39 RS00580
gene id: 1074467:JP39_RS00580
uniprot id: A0A0K2L9U5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS06825
gene id: 1074467:JP39_RS06825
uniprot id: A0A0K2LCS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1074467:JP39 RS03840
gene id: 1074467:JP39_RS03840
uniprot id: A0A0K2LB98
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1074467:JP39 RS07670
gene id: 1074467:JP39_RS07670
uniprot id: A0A0K2LDA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS07015
gene id: 1074467:JP39_RS07015
uniprot id: A0A0K2LCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1074467:JP39 RS10170
gene id: 1074467:JP39_RS10170
uniprot id: A0A0K2LET1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1074467:JP39 RS02215
gene id: 1074467:JP39_RS02215
uniprot id: A0A0K2LAJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1074467:JP39 RS07605
gene id: 1074467:JP39_RS07605
uniprot id: A0A0K2LD98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS07715
gene id: 1074467:JP39_RS07715
uniprot id: A0A0K2LD81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS02765
gene id: 1074467:JP39_RS02765
uniprot id: A0A0K2LAS6
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1074467:JP39 RS08380
gene id: 1074467:JP39_RS08380
uniprot id: A0A0K2LDM7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1074467:JP39 RS12150
gene id: 1074467:JP39_RS12150
uniprot id: A0A0K2LFI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS12055
gene id: 1074467:JP39_RS12055
uniprot id: A0A0K2LFG5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1074467:JP39 RS05770
gene id: 1074467:JP39_RS05770
uniprot id: A0A0K2LCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1074467:JP39 RS05585
gene id: 1074467:JP39_RS05585
uniprot id: A0A0K2LC82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1074467:JP39 RS05405
gene id: 1074467:JP39_RS05405
uniprot id: A0A0K2LC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1074467:JP39 RS10125
gene id: 1074467:JP39_RS10125
uniprot id: A0A0K2LEE6
names: Similarity
messages: Belongs to the XFP family.

1074467:JP39 RS04785
gene id: 1074467:JP39_RS04785
uniprot id: A0A0K2LC20
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1074467:JP39 RS12335
gene id: 1074467:JP39_RS12335
uniprot id: A0A0K2LFL0
names: Subcellular Location Annotation
messages: cell wall

1074467:JP39 RS10450
gene id: 1074467:JP39_RS10450
uniprot id: A0A0K2LEM1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1074467:JP39 RS01910
gene id: 1074467:JP39_RS01910
uniprot id: A0A0K2LAB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS10405
gene id: 1074467:JP39_RS10405
uniprot id: A0A0K2LEX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS04925
gene id: 1074467:JP39_RS04925
uniprot id: A0A0K2LBW4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1074467:JP39 RS07665
gene id: 1074467:JP39_RS07665
uniprot id: A0A0K2LD69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS06665
gene id: 1074467:JP39_RS06665
uniprot id: A0A0K2LCT7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1074467:JP39 RS02010
gene id: 1074467:JP39_RS02010
uniprot id: A0A0K2LAF8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1074467:JP39 RS09465
gene id: 1074467:JP39_RS09465
uniprot id: A0A0K2LE50
names: Similarity
messages: Belongs to the universal stress protein A family.

1074467:JP39 RS01715
gene id: 1074467:JP39_RS01715
uniprot id: A0A0K2LAI4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1074467:JP39 RS09485
gene id: 1074467:JP39_RS09485
uniprot id: A0A0K2LE47
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1074467:JP39 RS07315
gene id: 1074467:JP39_RS07315
uniprot id: A0A0K2LD11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS00155
gene id: 1074467:JP39_RS00155
uniprot id: A0A0K2L9N6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1074467:JP39 RS04475
gene id: 1074467:JP39_RS04475
uniprot id: A0A0K2LBJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS08520
gene id: 1074467:JP39_RS08520
uniprot id: A0A0K2LDL8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1074467:JP39 RS05050
gene id: 1074467:JP39_RS05050
uniprot id: A0A0K2LC71
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS04630
gene id: 1074467:JP39_RS04630
uniprot id: A0A0K2LBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11045
gene id: 1074467:JP39_RS11045
uniprot id: A0A0K2LEW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS10900
gene id: 1074467:JP39_RS10900
uniprot id: A0A0K2LET8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1074467:JP39 RS04250
gene id: 1074467:JP39_RS04250
uniprot id: A0A0K2LBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04900
gene id: 1074467:JP39_RS04900
uniprot id: A0A0K2LBV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS01255
gene id: 1074467:JP39_RS01255
uniprot id: A0A0K2LA29
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1074467:JP39 RS09230
gene id: 1074467:JP39_RS09230
uniprot id: A0A0K2LE94
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS00510
gene id: 1074467:JP39_RS00510
uniprot id: A0A0K2L9L1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1074467:JP39 RS07450
gene id: 1074467:JP39_RS07450
uniprot id: A0A0K2LD34
names: Similarity
messages: Belongs to the carbamate kinase family.

1074467:JP39 RS07165
gene id: 1074467:JP39_RS07165
uniprot id: A0A0K2LCY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1074467:JP39 RS07425
gene id: 1074467:JP39_RS07425
uniprot id: A0A0K2LDF8
names: Similarity
messages: Belongs to the UPF0342 family.

1074467:JP39 RS08260
gene id: 1074467:JP39_RS08260
uniprot id: A0A0K2LDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1074467:JP39 RS04945
gene id: 1074467:JP39_RS04945
uniprot id: A0A0K2LBT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1074467:JP39 RS08975
gene id: 1074467:JP39_RS08975
uniprot id: A0A0K2LDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS09890
gene id: 1074467:JP39_RS09890
uniprot id: A0A0K2LEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1074467:JP39 RS05940
gene id: 1074467:JP39_RS05940
uniprot id: A0A0K2LCA8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1074467:JP39 RS04225
gene id: 1074467:JP39_RS04225
uniprot id: A0A0K2LBF2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06950
gene id: 1074467:JP39_RS06950
uniprot id: A0A0K2LCY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1074467:JP39 RS06690
gene id: 1074467:JP39_RS06690
uniprot id: A0A0K2LCU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1074467:JP39 RS10260
gene id: 1074467:JP39_RS10260
uniprot id: A0A0K2LEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04660
gene id: 1074467:JP39_RS04660
uniprot id: A0A0K2LBR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1074467:JP39 RS04745
gene id: 1074467:JP39_RS04745
uniprot id: A0A0K2LBP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00115
gene id: 1074467:JP39_RS00115
uniprot id: A0A0K2L9G2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1074467:JP39 RS08770
gene id: 1074467:JP39_RS08770
uniprot id: A0A0K2LDR6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1074467:JP39 RS10895
gene id: 1074467:JP39_RS10895
uniprot id: A0A0K2LEX2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1074467:JP39 RS03630
gene id: 1074467:JP39_RS03630
uniprot id: A0A0K2LBE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS12035
gene id: 1074467:JP39_RS12035
uniprot id: A0A0K2LFQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1074467:JP39 RS06435
gene id: 1074467:JP39_RS06435
uniprot id: A0A0K2LCV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1074467:JP39 RS05255
gene id: 1074467:JP39_RS05255
uniprot id: A0A0K2LBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1074467:JP39 RS03170
gene id: 1074467:JP39_RS03170
uniprot id: A0A0K2LAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1074467:JP39 RS05195
gene id: 1074467:JP39_RS05195
uniprot id: A0A0K2LBX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS11020
gene id: 1074467:JP39_RS11020
uniprot id: A0A0K2LFZ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS11930
gene id: 1074467:JP39_RS11930
uniprot id: A0A0K2LFN1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1074467:JP39 RS09560
gene id: 1074467:JP39_RS09560
uniprot id: A0A0K2LE52
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1074467:JP39 RS08475
gene id: 1074467:JP39_RS08475
uniprot id: A0A0K2LDK9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1074467:JP39 RS08730
gene id: 1074467:JP39_RS08730
uniprot id: A0A0K2LE18
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS07040
gene id: 1074467:JP39_RS07040
uniprot id: A0A0K2LCW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1074467:JP39 RS01990
gene id: 1074467:JP39_RS01990
uniprot id: A0A0K2LAC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1074467:JP39 RS04620
gene id: 1074467:JP39_RS04620
uniprot id: A0A0K2LBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1074467:JP39 RS01855
gene id: 1074467:JP39_RS01855
uniprot id: A0A0K2LAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1074467:JP39 RS08325
gene id: 1074467:JP39_RS08325
uniprot id: A0A0K2LDL5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1074467:JP39 RS06835
gene id: 1074467:JP39_RS06835
uniprot id: A0A0K2LCS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1074467:JP39 RS05505
gene id: 1074467:JP39_RS05505
uniprot id: A0A0K2LFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1074467:JP39 RS06885
gene id: 1074467:JP39_RS06885
uniprot id: A0A0K2LD61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1074467:JP39 RS03425
gene id: 1074467:JP39_RS03425
uniprot id: A0A0K2LB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1074467:JP39 RS05245
gene id: 1074467:JP39_RS05245
uniprot id: A0A0K2LBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1074467:JP39 RS00045
gene id: 1074467:JP39_RS00045
uniprot id: A0A0K2L9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1074467:JP39 RS03955
gene id: 1074467:JP39_RS03955
uniprot id: A0A0K2LBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05350
gene id: 1074467:JP39_RS05350
uniprot id: A0A0K2LC42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1074467:JP39 RS04160
gene id: 1074467:JP39_RS04160
uniprot id: A0A0K2LBI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1074467:JP39 RS10790
gene id: 1074467:JP39_RS10790
uniprot id: A0A0K2LES4
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02120
gene id: 1074467:JP39_RS02120
uniprot id: A0A0K2LAD5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05075
gene id: 1074467:JP39_RS05075
uniprot id: A0A0K2LBV0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07455
gene id: 1074467:JP39_RS07455
uniprot id: A0A0K2LDG3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS08580
gene id: 1074467:JP39_RS08580
uniprot id: A0A0K2LDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1074467:JP39 RS10560
gene id: 1074467:JP39_RS10560
uniprot id: A0A0K2LEZ7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1074467:JP39 RS09950
gene id: 1074467:JP39_RS09950
uniprot id: A0A0K2LEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS09170
gene id: 1074467:JP39_RS09170
uniprot id: A0A0K2LDY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1074467:JP39 RS05990
gene id: 1074467:JP39_RS05990
uniprot id: A0A0K2LCC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1074467:JP39 RS11920
gene id: 1074467:JP39_RS11920
uniprot id: A0A0K2LFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1074467:JP39 RS00255
gene id: 1074467:JP39_RS00255
uniprot id: A0A0K2L9F6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1074467:JP39 RS10220
gene id: 1074467:JP39_RS10220
uniprot id: A0A0K2LEH7
names: Similarity
messages: Belongs to the thioredoxin family.

1074467:JP39 RS04795
gene id: 1074467:JP39_RS04795
uniprot id: A0A0K2LBU0
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1074467:JP39 RS07405
gene id: 1074467:JP39_RS07405
uniprot id: A0A0K2LD30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1074467:JP39 RS12325
gene id: 1074467:JP39_RS12325
uniprot id: A0A0K2L9C0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05895
gene id: 1074467:JP39_RS05895
uniprot id: A0A0K2LCA4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1074467:JP39 RS07825
gene id: 1074467:JP39_RS07825
uniprot id: A0A0K2LD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1074467:JP39 RS07340
gene id: 1074467:JP39_RS07340
uniprot id: A0A0K2LD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1074467:JP39 RS08705
gene id: 1074467:JP39_RS08705
uniprot id: A0A0K2LDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1074467:JP39 RS01925
gene id: 1074467:JP39_RS01925
uniprot id: A0A0K2LAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1074467:JP39 RS06060
gene id: 1074467:JP39_RS06060
uniprot id: A0A0K2LCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1074467:JP39 RS06550
gene id: 1074467:JP39_RS06550
uniprot id: A0A0K2LCX5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1074467:JP39 RS08080
gene id: 1074467:JP39_RS08080
uniprot id: A0A0K2LDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1074467:JP39 RS01270
gene id: 1074467:JP39_RS01270
uniprot id: A0A0K2LAA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1074467:JP39 RS08190
gene id: 1074467:JP39_RS08190
uniprot id: A0A0K2LDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1074467:JP39 RS03750
gene id: 1074467:JP39_RS03750
uniprot id: A0A0K2LBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02410
gene id: 1074467:JP39_RS02410
uniprot id: A0A0K2LAM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1074467:JP39 RS02645
gene id: 1074467:JP39_RS02645
uniprot id: A0A0K2LAQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1074467:JP39 RS08790
gene id: 1074467:JP39_RS08790
uniprot id: A0A0K2LDU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1074467:JP39 RS07095
gene id: 1074467:JP39_RS07095
uniprot id: A0A0K2LD08
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05970
gene id: 1074467:JP39_RS05970
uniprot id: A0A0K2LCB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1074467:JP39 RS11555
gene id: 1074467:JP39_RS11555
uniprot id: A0A0K2LF71
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1074467:JP39 RS02575
gene id: 1074467:JP39_RS02575
uniprot id: A0A0K2LAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1074467:JP39 RS00925
gene id: 1074467:JP39_RS00925
uniprot id: A0A0K2L9X7
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05625
gene id: 1074467:JP39_RS05625
uniprot id: A0A0K2LC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00245
gene id: 1074467:JP39_RS00245
uniprot id: A0A0K2L9I6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10670
gene id: 1074467:JP39_RS10670
uniprot id: A0A0K2LEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS10500
gene id: 1074467:JP39_RS10500
uniprot id: A0A0K2LEM6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1074467:JP39 RS08605
gene id: 1074467:JP39_RS08605
uniprot id: A0A0K2LDR5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1074467:JP39 RS01305
gene id: 1074467:JP39_RS01305
uniprot id: A0A0K2LA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1074467:JP39 RS09120
gene id: 1074467:JP39_RS09120
uniprot id: A0A0K2LDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11265
gene id: 1074467:JP39_RS11265
uniprot id: A0A0K2LF15
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1074467:JP39 RS01895
gene id: 1074467:JP39_RS01895
uniprot id: A0A0K2LAL4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1074467:JP39 RS07850
gene id: 1074467:JP39_RS07850
uniprot id: A0A0K2LD95
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1074467:JP39 RS02005
gene id: 1074467:JP39_RS02005
uniprot id: A0A0K2LAC4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1074467:JP39 RS07870
gene id: 1074467:JP39_RS07870
uniprot id: A0A0K2LDA1
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1074467:JP39 RS03130
gene id: 1074467:JP39_RS03130
uniprot id: A0A0K2LAZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1074467:JP39 RS10665
gene id: 1074467:JP39_RS10665
uniprot id: A0A0K2LES7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1074467:JP39 RS03575
gene id: 1074467:JP39_RS03575
uniprot id: A0A0K2LBC8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1074467:JP39 RS07645
gene id: 1074467:JP39_RS07645
uniprot id: A0A0K2LDA0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1074467:JP39 RS09505
gene id: 1074467:JP39_RS09505
uniprot id: A0A0K2LE46
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS03655
gene id: 1074467:JP39_RS03655
uniprot id: A0A0K2LB54
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1074467:JP39 RS00825
gene id: 1074467:JP39_RS00825
uniprot id: A0A0K2L9T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1074467:JP39 RS02260
gene id: 1074467:JP39_RS02260
uniprot id: A0A0K2LAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1074467:JP39 RS06830
gene id: 1074467:JP39_RS06830
uniprot id: A0A0K2LD51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1074467:JP39 RS01710
gene id: 1074467:JP39_RS01710
uniprot id: A0A0K2LA59
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1074467:JP39 RS06145
gene id: 1074467:JP39_RS06145
uniprot id: A0A0K2LCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06770
gene id: 1074467:JP39_RS06770
uniprot id: A0A0K2LCR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS05100
gene id: 1074467:JP39_RS05100
uniprot id: A0A0K2LBV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS11360
gene id: 1074467:JP39_RS11360
uniprot id: A0A0K2LF57
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06905
gene id: 1074467:JP39_RS06905
uniprot id: A0A0K2LCU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1074467:JP39 RS02385
gene id: 1074467:JP39_RS02385
uniprot id: A0A0K2LAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1074467:JP39 RS01555
gene id: 1074467:JP39_RS01555
uniprot id: A0A0K2LA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1074467:JP39 RS02340
gene id: 1074467:JP39_RS02340
uniprot id: A0A0K2LAU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05535
gene id: 1074467:JP39_RS05535
uniprot id: A0A0K2LC72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1074467:JP39 RS07035
gene id: 1074467:JP39_RS07035
uniprot id: A0A0K2LCW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1074467:JP39 RS04445
gene id: 1074467:JP39_RS04445
uniprot id: A0A0K2LBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1074467:JP39 RS01780
gene id: 1074467:JP39_RS01780
uniprot id: A0A0K2LA91
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1074467:JP39 RS10435
gene id: 1074467:JP39_RS10435
uniprot id: A0A0K2LEL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01380
gene id: 1074467:JP39_RS01380
uniprot id: A0A0K2LA16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02235
gene id: 1074467:JP39_RS02235
uniprot id: A0A0K2LAS5
names: Similarity
messages: Belongs to the TPP enzyme family.

1074467:JP39 RS02435
gene id: 1074467:JP39_RS02435
uniprot id: A0A0K2LAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1074467:JP39 RS05950
gene id: 1074467:JP39_RS05950
uniprot id: A0A0K2LCB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1074467:JP39 RS10390
gene id: 1074467:JP39_RS10390
uniprot id: A0A0K2LG90
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS08960
gene id: 1074467:JP39_RS08960
uniprot id: A0A0K2LFW2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1074467:JP39 RS02635
gene id: 1074467:JP39_RS02635
uniprot id: A0A0K2LAQ0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1074467:JP39 RS03210
gene id: 1074467:JP39_RS03210
uniprot id: A0A0K2LB07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1074467:JP39 RS06970
gene id: 1074467:JP39_RS06970
uniprot id: A0A0K2LD74
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1074467:JP39 RS04675
gene id: 1074467:JP39_RS04675
uniprot id: A0A0K2LC00
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS06505
gene id: 1074467:JP39_RS06505
uniprot id: A0A0K2LCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS11840
gene id: 1074467:JP39_RS11840
uniprot id: A0A0K2LFY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1074467:JP39 RS06360
gene id: 1074467:JP39_RS06360
uniprot id: A0A0K2LCT5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1074467:JP39 RS00555
gene id: 1074467:JP39_RS00555
uniprot id: A0A0K2L9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01500
gene id: 1074467:JP39_RS01500
uniprot id: A0A0K2LA69
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1074467:JP39 RS05450
gene id: 1074467:JP39_RS05450
uniprot id: A0A0K2LC21
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05090
gene id: 1074467:JP39_RS05090
uniprot id: A0A0K2LBZ4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1074467:JP39 RS00050
gene id: 1074467:JP39_RS00050
uniprot id: A0A0K2L9L7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1074467:JP39 RS08115
gene id: 1074467:JP39_RS08115
uniprot id: A0A0K2LDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1074467:JP39 RS11670
gene id: 1074467:JP39_RS11670
uniprot id: A0A0K2LF89
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08680
gene id: 1074467:JP39_RS08680
uniprot id: A0A0K2LDP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1074467:JP39 RS07840
gene id: 1074467:JP39_RS07840
uniprot id: A0A0K2LDD2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS01830
gene id: 1074467:JP39_RS01830
uniprot id: A0A0K2LAC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1074467:JP39 RS06055
gene id: 1074467:JP39_RS06055
uniprot id: A0A0K2LCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1074467:JP39 RS03155
gene id: 1074467:JP39_RS03155
uniprot id: A0A0K2LAX1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10645
gene id: 1074467:JP39_RS10645
uniprot id: A0A0K2LEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1074467:JP39 RS05525
gene id: 1074467:JP39_RS05525
uniprot id: A0A0K2LCF5
names: Similarity
messages: Belongs to the UPF0346 family.

1074467:JP39 RS02295
gene id: 1074467:JP39_RS02295
uniprot id: A0A0K2LAI0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07965
gene id: 1074467:JP39_RS07965
uniprot id: A0A0K2LDP0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1074467:JP39 RS00195
gene id: 1074467:JP39_RS00195
uniprot id: A0A0K2L9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1074467:JP39 RS05315
gene id: 1074467:JP39_RS05315
uniprot id: A0A0K2LCB9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1074467:JP39 RS09915
gene id: 1074467:JP39_RS09915
uniprot id: A0A0K2LEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1074467:JP39 RS08935
gene id: 1074467:JP39_RS08935
uniprot id: A0A0K2LDU2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1074467:JP39 RS06045
gene id: 1074467:JP39_RS06045
uniprot id: A0A0K2LCD2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1074467:JP39 RS00055
gene id: 1074467:JP39_RS00055
uniprot id: A0A0K2L9C5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1074467:JP39 RS00660
gene id: 1074467:JP39_RS00660
uniprot id: A0A0K2L9N4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1074467:JP39 RS04810
gene id: 1074467:JP39_RS04810
uniprot id: A0A0K2LC25
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1074467:JP39 RS08930
gene id: 1074467:JP39_RS08930
uniprot id: A0A0K2LE45
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1074467:JP39 RS07710
gene id: 1074467:JP39_RS07710
uniprot id: A0A0K2LDK2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1074467:JP39 RS07135
gene id: 1074467:JP39_RS07135
uniprot id: A0A0K2LCX8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS05230
gene id: 1074467:JP39_RS05230
uniprot id: A0A0K2LBY3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1074467:JP39 RS00745
gene id: 1074467:JP39_RS00745
uniprot id: A0A0K2L9S8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1074467:JP39 RS11710
gene id: 1074467:JP39_RS11710
uniprot id: A0A0K2LFJ0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00505
gene id: 1074467:JP39_RS00505
uniprot id: A0A0K2L9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1074467:JP39 RS02090
gene id: 1074467:JP39_RS02090
uniprot id: A0A0K2LAE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1074467:JP39 RS02740
gene id: 1074467:JP39_RS02740
uniprot id: A0A0K2LAS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1074467:JP39 RS11235
gene id: 1074467:JP39_RS11235
uniprot id: A0A0K2LF03
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS03115
gene id: 1074467:JP39_RS03115
uniprot id: A0A0K2LAU8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1074467:JP39 RS10765
gene id: 1074467:JP39_RS10765
uniprot id: A0A0K2LER9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS07790
gene id: 1074467:JP39_RS07790
uniprot id: A0A0K2LG62
names: Similarity
messages: Belongs to the DCK/DGK family.

1074467:JP39 RS05420
gene id: 1074467:JP39_RS05420
uniprot id: A0A0K2LC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1074467:JP39 RS05215
gene id: 1074467:JP39_RS05215
uniprot id: A0A0K2LCA0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1074467:JP39 RS07170
gene id: 1074467:JP39_RS07170
uniprot id: A0A0K2LDA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1074467:JP39 RS03185
gene id: 1074467:JP39_RS03185
uniprot id: A0A0K2LB00
names: Function
messages: Required for transformation and DNA binding.

1074467:JP39 RS07210
gene id: 1074467:JP39_RS07210
uniprot id: A0A0K2LCZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1074467:JP39 RS06445
gene id: 1074467:JP39_RS06445
uniprot id: A0A0K2LCJ9
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1074467:JP39 RS07220
gene id: 1074467:JP39_RS07220
uniprot id: A0A0K2LDB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS10530
gene id: 1074467:JP39_RS10530
uniprot id: A0A0K2LEN1
names: Similarity
messages: Belongs to the peptidase C69 family.

1074467:JP39 RS02000
gene id: 1074467:JP39_RS02000
uniprot id: A0A0K2LAN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1074467:JP39 RS04290
gene id: 1074467:JP39_RS04290
uniprot id: A0A0K2LBG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS12295
gene id: 1074467:JP39_RS12295
uniprot id: A0A0K2LFL3
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02195
gene id: 1074467:JP39_RS02195
uniprot id: A0A0K2LAF0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1074467:JP39 RS02695
gene id: 1074467:JP39_RS02695
uniprot id: A0A0K2LAT4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1074467:JP39 RS08055
gene id: 1074467:JP39_RS08055
uniprot id: A0A0K2LDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1074467:JP39 RS00835
gene id: 1074467:JP39_RS00835
uniprot id: A0A0K2L9Q7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1074467:JP39 RS03705
gene id: 1074467:JP39_RS03705
uniprot id: A0A0K2LB65
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS10690
gene id: 1074467:JP39_RS10690
uniprot id: A0A0K2LEQ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1074467:JP39 RS10315
gene id: 1074467:JP39_RS10315
uniprot id: A0A0K2LEH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS09495
gene id: 1074467:JP39_RS09495
uniprot id: A0A0K2LE54
names: Similarity
messages: Belongs to the EamA transporter family.

1074467:JP39 RS10200
gene id: 1074467:JP39_RS10200
uniprot id: A0A0K2LET6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1074467:JP39 RS03420
gene id: 1074467:JP39_RS03420
uniprot id: A0A0K2LB41
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS01250
gene id: 1074467:JP39_RS01250
uniprot id: A0A0K2L9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1074467:JP39 RS02660
gene id: 1074467:JP39_RS02660
uniprot id: A0A0K2LAQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1074467:JP39 RS05335
gene id: 1074467:JP39_RS05335
uniprot id: A0A0K2LC01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1074467:JP39 RS01620
gene id: 1074467:JP39_RS01620
uniprot id: A0A0K2LA44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05310
gene id: 1074467:JP39_RS05310
uniprot id: A0A0K2LBZ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1074467:JP39 RS02595
gene id: 1074467:JP39_RS02595
uniprot id: A0A0K2LAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1074467:JP39 RS00200
gene id: 1074467:JP39_RS00200
uniprot id: A0A0K2L9F8
names: Subunit
messages: Monomer.

1074467:JP39 RS10285
gene id: 1074467:JP39_RS10285
uniprot id: A0A0K2LEL3
names: Similarity
messages: Belongs to the Fur family.

1074467:JP39 RS02480
gene id: 1074467:JP39_RS02480
uniprot id: A0A0K2LAL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1074467:JP39 RS03880
gene id: 1074467:JP39_RS03880
uniprot id: A0A0K2LB96
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08985
gene id: 1074467:JP39_RS08985
uniprot id: A0A0K2LE55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01940
gene id: 1074467:JP39_RS01940
uniprot id: A0A0K2LAB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1074467:JP39 RS07820
gene id: 1074467:JP39_RS07820
uniprot id: A0A0K2LD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1074467:JP39 RS03540
gene id: 1074467:JP39_RS03540
uniprot id: A0A0K2LB35
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1074467:JP39 RS04825
gene id: 1074467:JP39_RS04825
uniprot id: A0A0K2LBQ6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1074467:JP39 RS03140
gene id: 1074467:JP39_RS03140
uniprot id: A0A0K2LAW7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1074467:JP39 RS05820
gene id: 1074467:JP39_RS05820
uniprot id: A0A0K2LC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1074467:JP39 RS08020
gene id: 1074467:JP39_RS08020
uniprot id: A0A0K2LDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1074467:JP39 RS00890
gene id: 1074467:JP39_RS00890
uniprot id: A0A0K2LA14
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1074467:JP39 RS01280
gene id: 1074467:JP39_RS01280
uniprot id: A0A0K2LA33
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1074467:JP39 RS05720
gene id: 1074467:JP39_RS05720
uniprot id: A0A0K2LC70
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1074467:JP39 RS09535
gene id: 1074467:JP39_RS09535
uniprot id: A0A0K2LE48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04935
gene id: 1074467:JP39_RS04935
uniprot id: A0A0K2LBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS00150
gene id: 1074467:JP39_RS00150
uniprot id: A0A0K2L9D7
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02705
gene id: 1074467:JP39_RS02705
uniprot id: A0A0K2LAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1074467:JP39 RS07925
gene id: 1074467:JP39_RS07925
uniprot id: A0A0K2LDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1074467:JP39 RS00495
gene id: 1074467:JP39_RS00495
uniprot id: A0A0K2L9T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1074467:JP39 RS09130
gene id: 1074467:JP39_RS09130
uniprot id: A0A0K2LE77
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1074467:JP39 RS02075
gene id: 1074467:JP39_RS02075
uniprot id: A0A0K2LAP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1074467:JP39 RS02210
gene id: 1074467:JP39_RS02210
uniprot id: A0A0K2LAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS09410
gene id: 1074467:JP39_RS09410
uniprot id: A0A0K2LE26
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1074467:JP39 RS05265
gene id: 1074467:JP39_RS05265
uniprot id: A0A0K2LCA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1074467:JP39 RS11750
gene id: 1074467:JP39_RS11750
uniprot id: A0A0K2LF97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1074467:JP39 RS08185
gene id: 1074467:JP39_RS08185
uniprot id: A0A0K2LG67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1074467:JP39 RS05260
gene id: 1074467:JP39_RS05260
uniprot id: A0A0K2LBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1074467:JP39 RS02375
gene id: 1074467:JP39_RS02375
uniprot id: A0A0K2LAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1074467:JP39 RS04955
gene id: 1074467:JP39_RS04955
uniprot id: A0A0K2LBT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS08130
gene id: 1074467:JP39_RS08130
uniprot id: A0A0K2LDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1074467:JP39 RS05095
gene id: 1074467:JP39_RS05095
uniprot id: A0A0K2LBV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS07930
gene id: 1074467:JP39_RS07930
uniprot id: A0A0K2LDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08445
gene id: 1074467:JP39_RS08445
uniprot id: A0A0K2LDK0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10030
gene id: 1074467:JP39_RS10030
uniprot id: A0A0K2LEE3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1074467:JP39 RS05235
gene id: 1074467:JP39_RS05235
uniprot id: A0A0K2LBY0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1074467:JP39 RS08945
gene id: 1074467:JP39_RS08945
uniprot id: A0A0K2LDU4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1074467:JP39 RS06355
gene id: 1074467:JP39_RS06355
uniprot id: A0A0K2LCI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00725
gene id: 1074467:JP39_RS00725
uniprot id: A0A0K2L9Q0
names: Similarity
messages: Belongs to the UPF0177 family.

1074467:JP39 RS08890
gene id: 1074467:JP39_RS08890
uniprot id: A0A0K2LDT6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00575
gene id: 1074467:JP39_RS00575
uniprot id: A0A0K2L9K8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1074467:JP39 RS07265
gene id: 1074467:JP39_RS07265
uniprot id: A0A0K2LD00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1074467:JP39 RS09815
gene id: 1074467:JP39_RS09815
uniprot id: A0A0K2LE96
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11985
gene id: 1074467:JP39_RS11985
uniprot id: A0A0K2LFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1074467:JP39 RS04010
gene id: 1074467:JP39_RS04010
uniprot id: A0A0K2LBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05865
gene id: 1074467:JP39_RS05865
uniprot id: A0A0K2LCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02655
gene id: 1074467:JP39_RS02655
uniprot id: A0A0K2LB03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1074467:JP39 RS06780
gene id: 1074467:JP39_RS06780
uniprot id: A0A0K2LD41
names: Similarity
messages: Belongs to the EamA transporter family.

1074467:JP39 RS01550
gene id: 1074467:JP39_RS01550
uniprot id: A0A0K2LA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS07985
gene id: 1074467:JP39_RS07985
uniprot id: A0A0K2LDC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1074467:JP39 RS10770
gene id: 1074467:JP39_RS10770
uniprot id: A0A0K2LEU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1074467:JP39 RS01670
gene id: 1074467:JP39_RS01670
uniprot id: A0A0K2LA71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS08600
gene id: 1074467:JP39_RS08600
uniprot id: A0A0K2LDN1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1074467:JP39 RS03145
gene id: 1074467:JP39_RS03145
uniprot id: A0A0K2LAV3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS06685
gene id: 1074467:JP39_RS06685
uniprot id: A0A0K2LCQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1074467:JP39 RS11550
gene id: 1074467:JP39_RS11550
uniprot id: A0A0K2LF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01690
gene id: 1074467:JP39_RS01690
uniprot id: A0A0K2LFN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05340
gene id: 1074467:JP39_RS05340
uniprot id: A0A0K2LCC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1074467:JP39 RS04110
gene id: 1074467:JP39_RS04110
uniprot id: A0A0K2LBD3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1074467:JP39 RS08610
gene id: 1074467:JP39_RS08610
uniprot id: A0A0K2LDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS11740
gene id: 1074467:JP39_RS11740
uniprot id: A0A0K2LF99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1074467:JP39 RS05190
gene id: 1074467:JP39_RS05190
uniprot id: A0A0K2LC95
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1074467:JP39 RS06520
gene id: 1074467:JP39_RS06520
uniprot id: A0A0K2LCL3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1074467:JP39 RS04525
gene id: 1074467:JP39_RS04525
uniprot id: A0A0K2LBK3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1074467:JP39 RS01775
gene id: 1074467:JP39_RS01775
uniprot id: A0A0K2LAB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1074467:JP39 RS04035
gene id: 1074467:JP39_RS04035
uniprot id: A0A0K2LBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1074467:JP39 RS06725
gene id: 1074467:JP39_RS06725
uniprot id: A0A0K2LCR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1074467:JP39 RS04895
gene id: 1074467:JP39_RS04895
uniprot id: A0A0K2LBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1074467:JP39 RS10175
gene id: 1074467:JP39_RS10175
uniprot id: A0A0K2LEG1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1074467:JP39 RS00650
gene id: 1074467:JP39_RS00650
uniprot id: A0A0K2L9M4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1074467:JP39 RS01820
gene id: 1074467:JP39_RS01820
uniprot id: A0A0K2LAJ9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1074467:JP39 RS06720
gene id: 1074467:JP39_RS06720
uniprot id: A0A0K2LCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1074467:JP39 RS07590
gene id: 1074467:JP39_RS07590
uniprot id: A0A0K2LDI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS02125
gene id: 1074467:JP39_RS02125
uniprot id: A0A0K2LAQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1074467:JP39 RS04135
gene id: 1074467:JP39_RS04135
uniprot id: A0A0K2LBH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS11990
gene id: 1074467:JP39_RS11990
uniprot id: A0A0K2LFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01660
gene id: 1074467:JP39_RS01660
uniprot id: A0A0K2LA62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1074467:JP39 RS08100
gene id: 1074467:JP39_RS08100
uniprot id: A0A0K2LDE1
names: Similarity
messages: Belongs to the IMPACT family.

1074467:JP39 RS11965
gene id: 1074467:JP39_RS11965
uniprot id: A0A0K2LFG4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1074467:JP39 RS06640
gene id: 1074467:JP39_RS06640
uniprot id: A0A0K2LCT2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1074467:JP39 RS11015
gene id: 1074467:JP39_RS11015
uniprot id: A0A0K2LEW3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1074467:JP39 RS07065
gene id: 1074467:JP39_RS07065
uniprot id: A0A0K2LCX0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1074467:JP39 RS02025
gene id: 1074467:JP39_RS02025
uniprot id: A0A0K2LAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1074467:JP39 RS08895
gene id: 1074467:JP39_RS08895
uniprot id: A0A0K2LDT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1074467:JP39 RS07945
gene id: 1074467:JP39_RS07945
uniprot id: A0A0K2LDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03920
gene id: 1074467:JP39_RS03920
uniprot id: A0A0K2LBB0
names: Similarity
messages: Belongs to the UPF0735 family.

1074467:JP39 RS04650
gene id: 1074467:JP39_RS04650
uniprot id: A0A0K2LBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1074467:JP39 RS01055
gene id: 1074467:JP39_RS01055
uniprot id: A0A0K2L9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1074467:JP39 RS05550
gene id: 1074467:JP39_RS05550
uniprot id: A0A0K2LCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1074467:JP39 RS11775
gene id: 1074467:JP39_RS11775
uniprot id: A0A0K2LFA2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1074467:JP39 RS01170
gene id: 1074467:JP39_RS01170
uniprot id: A0A0K2L9X8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10830
gene id: 1074467:JP39_RS10830
uniprot id: A0A0K2LET5
names: Similarity
messages: Belongs to the phosphopentomutase family.

1074467:JP39 RS09630
gene id: 1074467:JP39_RS09630
uniprot id: A0A0K2LE64
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1074467:JP39 RS04580
gene id: 1074467:JP39_RS04580
uniprot id: A0A0K2LBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1074467:JP39 RS06085
gene id: 1074467:JP39_RS06085
uniprot id: A0A0K2LCD5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1074467:JP39 RS00610
gene id: 1074467:JP39_RS00610
uniprot id: A0A0K2L9M3
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

1074467:JP39 RS05500
gene id: 1074467:JP39_RS05500
uniprot id: A0A0K2LC31
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1074467:JP39 RS02275
gene id: 1074467:JP39_RS02275
uniprot id: A0A0K2LAK5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11585
gene id: 1074467:JP39_RS11585
uniprot id: A0A0K2LFI1
names: Similarity
messages: Belongs to the peptidase C40 family.

1074467:JP39 RS11810
gene id: 1074467:JP39_RS11810
uniprot id: A0A0K2LFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1074467:JP39 RS05430
gene id: 1074467:JP39_RS05430
uniprot id: A0A0K2LC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1074467:JP39 RS04560
gene id: 1074467:JP39_RS04560
uniprot id: A0A0K2LBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1074467:JP39 RS10880
gene id: 1074467:JP39_RS10880
uniprot id: A0A0K2LEU5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1074467:JP39 RS00785
gene id: 1074467:JP39_RS00785
uniprot id: A0A0K2L9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS07305
gene id: 1074467:JP39_RS07305
uniprot id: A0A0K2LD10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1074467:JP39 RS01950
gene id: 1074467:JP39_RS01950
uniprot id: A0A0K2LAM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1074467:JP39 RS11295
gene id: 1074467:JP39_RS11295
uniprot id: A0A0K2LF21
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1074467:JP39 RS03670
gene id: 1074467:JP39_RS03670
uniprot id: A0A0K2LB60
names: Subcellular Location Annotation
messages: cytosol

1074467:JP39 RS01695
gene id: 1074467:JP39_RS01695
uniprot id: A0A0K2LA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1074467:JP39 RS07865
gene id: 1074467:JP39_RS07865
uniprot id: A0A0K2LDD7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1074467:JP39 RS06535
gene id: 1074467:JP39_RS06535
uniprot id: A0A0K2LCN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1074467:JP39 RS10940
gene id: 1074467:JP39_RS10940
uniprot id: A0A0K2LEV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1074467:JP39 RS05380
gene id: 1074467:JP39_RS05380
uniprot id: A0A0K2LC10
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1074467:JP39 RS10190
gene id: 1074467:JP39_RS10190
uniprot id: A0A0K2LEF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS01625
gene id: 1074467:JP39_RS01625
uniprot id: A0A0K2LAG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1074467:JP39 RS02455
gene id: 1074467:JP39_RS02455
uniprot id: A0A0K2LAL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1074467:JP39 RS06040
gene id: 1074467:JP39_RS06040
uniprot id: A0A0K2LCG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1074467:JP39 RS06875
gene id: 1074467:JP39_RS06875
uniprot id: A0A0K2LCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1074467:JP39 RS12250
gene id: 1074467:JP39_RS12250
uniprot id: A0A0K2LFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1074467:JP39 RS06705
gene id: 1074467:JP39_RS06705
uniprot id: A0A0K2LD27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1074467:JP39 RS12195
gene id: 1074467:JP39_RS12195
uniprot id: A0A0K2LFV0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1074467:JP39 RS05980
gene id: 1074467:JP39_RS05980
uniprot id: A0A0K2LCB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1074467:JP39 RS00640
gene id: 1074467:JP39_RS00640
uniprot id: A0A0K2L9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1074467:JP39 RS04635
gene id: 1074467:JP39_RS04635
uniprot id: A0A0K2LBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1074467:JP39 RS08310
gene id: 1074467:JP39_RS08310
uniprot id: A0A0K2LDU5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1074467:JP39 RS01965
gene id: 1074467:JP39_RS01965
uniprot id: A0A0K2LAC1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS04790
gene id: 1074467:JP39_RS04790
uniprot id: A0A0K2LBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1074467:JP39 RS05615
gene id: 1074467:JP39_RS05615
uniprot id: A0A0K2LC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00270
gene id: 1074467:JP39_RS00270
uniprot id: A0A0K2L9J1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02185
gene id: 1074467:JP39_RS02185
uniprot id: A0A0K2LAJ0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1074467:JP39 RS10795
gene id: 1074467:JP39_RS10795
uniprot id: A0A0K2LEV2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08780
gene id: 1074467:JP39_RS08780
uniprot id: A0A0K2LE29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1074467:JP39 RS03820
gene id: 1074467:JP39_RS03820
uniprot id: A0A0K2LB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02040
gene id: 1074467:JP39_RS02040
uniprot id: A0A0K2LAD6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1074467:JP39 RS04600
gene id: 1074467:JP39_RS04600
uniprot id: A0A0K2LBL8
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1074467:JP39 RS05035
gene id: 1074467:JP39_RS05035
uniprot id: A0A0K2LBY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS03580
gene id: 1074467:JP39_RS03580
uniprot id: A0A0K2LB47
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08395
gene id: 1074467:JP39_RS08395
uniprot id: A0A0K2LDJ0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1074467:JP39 RS00190
gene id: 1074467:JP39_RS00190
uniprot id: A0A0K2L9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1074467:JP39 RS00225
gene id: 1074467:JP39_RS00225
uniprot id: A0A0K2L9G3
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1074467:JP39 RS09840
gene id: 1074467:JP39_RS09840
uniprot id: A0A0K2LEA1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1074467:JP39 RS08015
gene id: 1074467:JP39_RS08015
uniprot id: A0A0K2LDC7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1074467:JP39 RS02035
gene id: 1074467:JP39_RS02035
uniprot id: A0A0K2LAG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1074467:JP39 RS08670
gene id: 1074467:JP39_RS08670
uniprot id: A0A0K2LDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1074467:JP39 RS06525
gene id: 1074467:JP39_RS06525
uniprot id: A0A0K2LCW8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1074467:JP39 RS12290
gene id: 1074467:JP39_RS12290
uniprot id: A0A0K2LFK4
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS05460
gene id: 1074467:JP39_RS05460
uniprot id: A0A0K2LC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS04055
gene id: 1074467:JP39_RS04055
uniprot id: A0A0K2LBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1074467:JP39 RS08235
gene id: 1074467:JP39_RS08235
uniprot id: A0A0K2LDG5
names: Similarity
messages: Belongs to the YoeB family.

1074467:JP39 RS01765
gene id: 1074467:JP39_RS01765
uniprot id: A0A0K2LAJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1074467:JP39 RS08785
gene id: 1074467:JP39_RS08785
uniprot id: A0A0K2LDR7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1074467:JP39 RS02445
gene id: 1074467:JP39_RS02445
uniprot id: A0A0K2LAJ6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1074467:JP39 RS06420
gene id: 1074467:JP39_RS06420
uniprot id: A0A0K2LCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

1074467:JP39 RS10585
gene id: 1074467:JP39_RS10585
uniprot id: A0A0K2LF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1074467:JP39 RS02580
gene id: 1074467:JP39_RS02580
uniprot id: A0A0K2LAP0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1074467:JP39 RS08245
gene id: 1074467:JP39_RS08245
uniprot id: A0A0K2LDG6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1074467:JP39 RS08050
gene id: 1074467:JP39_RS08050
uniprot id: A0A0K2LFX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1074467:JP39 RS01260
gene id: 1074467:JP39_RS01260
uniprot id: A0A0K2LA03
names: Similarity
messages: Belongs to the DltD family.

1074467:JP39 RS06075
gene id: 1074467:JP39_RS06075
uniprot id: A0A0K2LCD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1074467:JP39 RS11820
gene id: 1074467:JP39_RS11820
uniprot id: A0A0K2LFB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1074467:JP39 RS05850
gene id: 1074467:JP39_RS05850
uniprot id: A0A0K2LC93
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS10240
gene id: 1074467:JP39_RS10240
uniprot id: A0A0K2LEG3
names: Similarity
messages: Belongs to the Fur family.

1074467:JP39 RS10430
gene id: 1074467:JP39_RS10430
uniprot id: A0A0K2LEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS12135
gene id: 1074467:JP39_RS12135
uniprot id: A0A0K2LFI0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1074467:JP39 RS04380
gene id: 1074467:JP39_RS04380
uniprot id: A0A0K2LBU6
names: Similarity
messages: Belongs to the UPF0177 family.

1074467:JP39 RS12160
gene id: 1074467:JP39_RS12160
uniprot id: A0A0K2LFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1074467:JP39 RS05415
gene id: 1074467:JP39_RS05415
uniprot id: A0A0K2LCD4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1074467:JP39 RS03615
gene id: 1074467:JP39_RS03615
uniprot id: A0A0K2LB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03120
gene id: 1074467:JP39_RS03120
uniprot id: A0A0K2LB63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1074467:JP39 RS08760
gene id: 1074467:JP39_RS08760
uniprot id: A0A0K2LDR2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1074467:JP39 RS01930
gene id: 1074467:JP39_RS01930
uniprot id: A0A0K2LAA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS00515
gene id: 1074467:JP39_RS00515
uniprot id: A0A0K2L9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1074467:JP39 RS06110
gene id: 1074467:JP39_RS06110
uniprot id: A0A0K2LCD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1074467:JP39 RS08195
gene id: 1074467:JP39_RS08195
uniprot id: A0A0K2LDF6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1074467:JP39 RS01315
gene id: 1074467:JP39_RS01315
uniprot id: A0A0K2LA12
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1074467:JP39 RS02500
gene id: 1074467:JP39_RS02500
uniprot id: A0A0K2LAX4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1074467:JP39 RS01515
gene id: 1074467:JP39_RS01515
uniprot id: A0A0K2LAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS01885
gene id: 1074467:JP39_RS01885
uniprot id: A0A0K2LAA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1074467:JP39 RS06735
gene id: 1074467:JP39_RS06735
uniprot id: A0A0K2LCR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS05435
gene id: 1074467:JP39_RS05435
uniprot id: A0A0K2LC17
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1074467:JP39 RS07990
gene id: 1074467:JP39_RS07990
uniprot id: A0A0K2LDP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS03470
gene id: 1074467:JP39_RS03470
uniprot id: A0A0K2LB51
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00210
gene id: 1074467:JP39_RS00210
uniprot id: A0A0K2L9P6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1074467:JP39 RS06645
gene id: 1074467:JP39_RS06645
uniprot id: A0A0K2LCP8
names: Similarity
messages: Belongs to the UPF0213 family.

1074467:JP39 RS03280
gene id: 1074467:JP39_RS03280
uniprot id: A0A0K2LAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS02335
gene id: 1074467:JP39_RS02335
uniprot id: A0A0K2LAH6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02175
gene id: 1074467:JP39_RS02175
uniprot id: A0A0K2LAR5
names: Similarity
messages: Belongs to the threonine synthase family.

1074467:JP39 RS11770
gene id: 1074467:JP39_RS11770
uniprot id: A0A0K2LFD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1074467:JP39 RS10010
gene id: 1074467:JP39_RS10010
uniprot id: A0A0K2LED2
names: Similarity
messages: Belongs to the universal stress protein A family.

1074467:JP39 RS04150
gene id: 1074467:JP39_RS04150
uniprot id: A0A0K2LBQ9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1074467:JP39 RS08535
gene id: 1074467:JP39_RS08535
uniprot id: A0A0K2LDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS05030
gene id: 1074467:JP39_RS05030
uniprot id: A0A0K2LBU8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1074467:JP39 RS02370
gene id: 1074467:JP39_RS02370
uniprot id: A0A0K2LAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1074467:JP39 RS08570
gene id: 1074467:JP39_RS08570
uniprot id: A0A0K2LDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1074467:JP39 RS04095
gene id: 1074467:JP39_RS04095
uniprot id: A0A0K2LBD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS07440
gene id: 1074467:JP39_RS07440
uniprot id: A0A0K2LD73
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08165
gene id: 1074467:JP39_RS08165
uniprot id: A0A0K2LDF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS12280
gene id: 1074467:JP39_RS12280
uniprot id: A0A0K2LFK2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1074467:JP39 RS03220
gene id: 1074467:JP39_RS03220
uniprot id: A0A0K2LAW8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1074467:JP39 RS05610
gene id: 1074467:JP39_RS05610
uniprot id: A0A0K2LCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS00370
gene id: 1074467:JP39_RS00370
uniprot id: A0A0K2L9S5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08540
gene id: 1074467:JP39_RS08540
uniprot id: A0A0K2LDM2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1074467:JP39 RS04500
gene id: 1074467:JP39_RS04500
uniprot id: A0A0K2LBJ9
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS10095
gene id: 1074467:JP39_RS10095
uniprot id: A0A0K2LEI0
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS08990
gene id: 1074467:JP39_RS08990
uniprot id: A0A0K2LDV2
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS07585
gene id: 1074467:JP39_RS07585
uniprot id: A0A0K2LFV2
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS00845
gene id: 1074467:JP39_RS00845
uniprot id: A0A0K2L9R8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1074467:JP39 RS02795
gene id: 1074467:JP39_RS02795
uniprot id: A0A0K2LAV5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1074467:JP39 RS06920
gene id: 1074467:JP39_RS06920
uniprot id: A0A0K2LCU4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1074467:JP39 RS04610
gene id: 1074467:JP39_RS04610
uniprot id: A0A0K2LBL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1074467:JP39 RS04440
gene id: 1074467:JP39_RS04440
uniprot id: A0A0K2LFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1074467:JP39 RS10730
gene id: 1074467:JP39_RS10730
uniprot id: A0A0K2LER5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1074467:JP39 RS11305
gene id: 1074467:JP39_RS11305
uniprot id: A0A0K2LF19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1074467:JP39 RS04480
gene id: 1074467:JP39_RS04480
uniprot id: A0A0K2LBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1074467:JP39 RS00235
gene id: 1074467:JP39_RS00235
uniprot id: A0A0K2L9Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1074467:JP39 RS03265
gene id: 1074467:JP39_RS03265
uniprot id: A0A0K2LAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS12220
gene id: 1074467:JP39_RS12220
uniprot id: A0A0K2LFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1074467:JP39 RS04845
gene id: 1074467:JP39_RS04845
uniprot id: A0A0K2LBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1074467:JP39 RS10370
gene id: 1074467:JP39_RS10370
uniprot id: A0A0K2LEK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS06610
gene id: 1074467:JP39_RS06610
uniprot id: A0A0K2LCP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1074467:JP39 RS01120
gene id: 1074467:JP39_RS01120
uniprot id: A0A0K2L9W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06900
gene id: 1074467:JP39_RS06900
uniprot id: A0A0K2LCY2
names: Similarity
messages: Belongs to the asp23 family.

1074467:JP39 RS04680
gene id: 1074467:JP39_RS04680
uniprot id: A0A0K2LBN3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1074467:JP39 RS11385
gene id: 1074467:JP39_RS11385
uniprot id: A0A0K2LF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08980
gene id: 1074467:JP39_RS08980
uniprot id: A0A0K2LDV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1074467:JP39 RS00770
gene id: 1074467:JP39_RS00770
uniprot id: A0A0K2L9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1074467:JP39 RS07025
gene id: 1074467:JP39_RS07025
uniprot id: A0A0K2LCW5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1074467:JP39 RS03055
gene id: 1074467:JP39_RS03055
uniprot id: A0A0K2LAX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08300
gene id: 1074467:JP39_RS08300
uniprot id: A0A0K2LDH6
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS09240
gene id: 1074467:JP39_RS09240
uniprot id: A0A0K2LE27
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS11350
gene id: 1074467:JP39_RS11350
uniprot id: A0A0K2LFD9
names: Similarity
messages: Belongs to the PRORSD1 family.

1074467:JP39 RS01375
gene id: 1074467:JP39_RS01375
uniprot id: A0A0K2LAC7
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06630
gene id: 1074467:JP39_RS06630
uniprot id: A0A0K2LD12
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1074467:JP39 RS09095
gene id: 1074467:JP39_RS09095
uniprot id: A0A0K2LE73
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1074467:JP39 RS08025
gene id: 1074467:JP39_RS08025
uniprot id: A0A0K2LDD0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1074467:JP39 RS12260
gene id: 1074467:JP39_RS12260
uniprot id: A0A0K2LFM5
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS02525
gene id: 1074467:JP39_RS02525
uniprot id: A0A0K2LAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1074467:JP39 RS02490
gene id: 1074467:JP39_RS02490
uniprot id: A0A0K2LAM2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1074467:JP39 RS04210
gene id: 1074467:JP39_RS04210
uniprot id: A0A0K2LBR8
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS07005
gene id: 1074467:JP39_RS07005
uniprot id: A0A0K2LCZ7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1074467:JP39 RS11190
gene id: 1074467:JP39_RS11190
uniprot id: A0A0K2LF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1074467:JP39 RS05790
gene id: 1074467:JP39_RS05790
uniprot id: A0A0K2LC84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1074467:JP39 RS04235
gene id: 1074467:JP39_RS04235
uniprot id: A0A0K2LBS2
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS01880
gene id: 1074467:JP39_RS01880
uniprot id: A0A0K2LAD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1074467:JP39 RS08110
gene id: 1074467:JP39_RS08110
uniprot id: A0A0K2LFW1
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06635
gene id: 1074467:JP39_RS06635
uniprot id: A0A0K2LCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1074467:JP39 RS11915
gene id: 1074467:JP39_RS11915
uniprot id: A0A0K2LFF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell.

1074467:JP39 RS00585
gene id: 1074467:JP39_RS00585
uniprot id: A0A0K2L9L9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1074467:JP39 RS04575
gene id: 1074467:JP39_RS04575
uniprot id: A0A0K2LBL3
names: Similarity
messages: Belongs to the UPF0758 family.

1074467:JP39 RS01850
gene id: 1074467:JP39_RS01850
uniprot id: A0A0K2LA92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1074467:JP39 RS09330
gene id: 1074467:JP39_RS09330
uniprot id: A0A0K2LE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1074467:JP39 RS07685
gene id: 1074467:JP39_RS07685
uniprot id: A0A0K2LDJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1074467:JP39 RS10800
gene id: 1074467:JP39_RS10800
uniprot id: A0A0K2LER8
names: Subcellular Location Annotation
messages: Cytoplasm

1074467:JP39 RS11010
gene id: 1074467:JP39_RS11010
uniprot id: A0A0K2LF76
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1074467:JP39 RS04590
gene id: 1074467:JP39_RS04590
uniprot id: A0A0K2LBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1074467:JP39 RS01085
gene id: 1074467:JP39_RS01085
uniprot id: A0A0K2LA04
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1074467:JP39 RS07465
gene id: 1074467:JP39_RS07465
uniprot id: A0A0K2LD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1074467:JP39 RS00405
gene id: 1074467:JP39_RS00405
uniprot id: A0A0K2L9I8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1074467:JP39 RS11380
gene id: 1074467:JP39_RS11380
uniprot id: A0A0K2LF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS08005
gene id: 1074467:JP39_RS08005
uniprot id: A0A0K2LDC6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1074467:JP39 RS10365
gene id: 1074467:JP39_RS10365
uniprot id: A0A0K2LEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1074467:JP39 RS07470
gene id: 1074467:JP39_RS07470
uniprot id: A0A0K2LD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1074467:JP39 RS07955
gene id: 1074467:JP39_RS07955
uniprot id: A0A0K2LDB6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1074467:JP39 RS08775
gene id: 1074467:JP39_RS08775
uniprot id: A0A0K2LDR4
names: Subcellular Location Annotation
messages: Membrane

1074467:JP39 RS06715
gene id: 1074467:JP39_RS06715
uniprot id: A0A0K2LCU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1074467:JP39 RS04820
gene id: 1074467:JP39_RS04820
uniprot id: A0A0K2LBU4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1074467:JP39 RS03535
gene id: 1074467:JP39_RS03535
uniprot id: A0A0K2LB61
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1074467:JP39 RS07230
gene id: 1074467:JP39_RS07230
uniprot id: A0A0K2LD33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1074467:JP39 RS06560
gene id: 1074467:JP39_RS06560
uniprot id: A0A0K2LCP4
names: Similarity
messages: Belongs to the ribF family.

1074467:JP39 RS07260
gene id: 1074467:JP39_RS07260
uniprot id: A0A0K2LD02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1074467:JP39 RS07810
gene id: 1074467:JP39_RS07810
uniprot id: A0A0K2LD91
names: Similarity
messages: Belongs to the peptidase S66 family.

1074467:JP39 RS01740
gene id: 1074467:JP39_RS01740
uniprot id: A0A0K2LAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1074467:JP39 RS02420
gene id: 1074467:JP39_RS02420
uniprot id: A0A0K2LAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1074467:JP39 RS05285
gene id: 1074467:JP39_RS05285
uniprot id: A0A0K2LBZ1
names: Similarity
messages: Belongs to the LOG family.

1074467:JP39 RS00595
gene id: 1074467:JP39_RS00595
uniprot id: A0A0K2L9M5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1074467:JP39 RS12305
gene id: 1074467:JP39_RS12305
uniprot id: A0A0K2LFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1074467:JP39 RS06945
gene id: 1074467:JP39_RS06945
uniprot id: A0A0K2LCU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1074467:JP39 RS12115
gene id: 1074467:JP39_RS12115
uniprot id: A0A0K2LFS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1074467:JP39 RS05325
gene id: 1074467:JP39_RS05325
uniprot id: A0A0K2LC37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1074467:JP39 RS07505
gene id: 1074467:JP39_RS07505
uniprot id: A0A0K2LD47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.