1071382:KAFR 0G02790
gene id: 1071382:KAFR_0G02790
uniprot id: H2AY60
names: Similarity
messages: Belongs to the MAPRE family.

1071382:KAFR 0K00500
gene id: 1071382:KAFR_0K00500
uniprot id: H2B1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0C02030
gene id: 1071382:KAFR_0C02030
uniprot id: H2AS46
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B02630
gene id: 1071382:KAFR_0B02630
uniprot id: H2AQB0
names: Similarity
messages: Belongs to the 14-3-3 family.

1071382:KAFR 0A07650
gene id: 1071382:KAFR_0A07650
uniprot id: H2AP99
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J00120
gene id: 1071382:KAFR_0J00120
uniprot id: H2B0D0
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

1071382:KAFR 0A00160
gene id: 1071382:KAFR_0A00160
uniprot id: H2AM54
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

1071382:KAFR 0E01910
gene id: 1071382:KAFR_0E01910
uniprot id: H2AVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

1071382:KAFR 0E00840
gene id: 1071382:KAFR_0E00840
uniprot id: H2AV38
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

1071382:KAFR 0G03120
gene id: 1071382:KAFR_0G03120
uniprot id: H2AY94
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1071382:KAFR 0E04290
gene id: 1071382:KAFR_0E04290
uniprot id: H2AW30
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071382:KAFR 0E01690
gene id: 1071382:KAFR_0E01690
uniprot id: H2AVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

1071382:KAFR 0D01190
gene id: 1071382:KAFR_0D01190
uniprot id: H2ATR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0D04770
gene id: 1071382:KAFR_0D04770
uniprot id: H2AUS4
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

1071382:KAFR 0C03720
gene id: 1071382:KAFR_0C03720
uniprot id: H2ASL4
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071382:KAFR 0C00940
gene id: 1071382:KAFR_0C00940
uniprot id: H2ART9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0G00340
gene id: 1071382:KAFR_0G00340
uniprot id: H2AXG7
names: Similarity
messages: Belongs to the PGA52 family.

1071382:KAFR 0F04110
gene id: 1071382:KAFR_0F04110
uniprot id: H2AXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1071382:KAFR 0C05230
gene id: 1071382:KAFR_0C05230
uniprot id: H2AT14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

1071382:KAFR 0E02890
gene id: 1071382:KAFR_0E02890
uniprot id: H2AVP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

1071382:KAFR 0C05640
gene id: 1071382:KAFR_0C05640
uniprot id: H2AT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

1071382:KAFR 0B00780
gene id: 1071382:KAFR_0B00780
uniprot id: H2APS6
names: Similarity
messages: Belongs to the TIP41 family.

1071382:KAFR 0L01580
gene id: 1071382:KAFR_0L01580
uniprot id: H2B2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

1071382:KAFR 0C02770
gene id: 1071382:KAFR_0C02770
uniprot id: H2ASC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

1071382:KAFR 0C04950
gene id: 1071382:KAFR_0C04950
uniprot id: H2ASY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

1071382:KAFR 0C05780
gene id: 1071382:KAFR_0C05780
uniprot id: H2AT69
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

1071382:KAFR 0A03250
gene id: 1071382:KAFR_0A03250
uniprot id: H2AN10
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

1071382:KAFR 0H02720
gene id: 1071382:KAFR_0H02720
uniprot id: H2AZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC29 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Links the central plaque component SPC42 to the inner plaque component SPC110.
messages: Nucleus
messages: spindle pole body

1071382:KAFR 0B00940
gene id: 1071382:KAFR_0B00940
uniprot id: H2APU2
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

1071382:KAFR 0B04460
gene id: 1071382:KAFR_0B04460
uniprot id: H2AQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0F00280
gene id: 1071382:KAFR_0F00280
uniprot id: H2AW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0F01430
gene id: 1071382:KAFR_0F01430
uniprot id: H2AWI9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G00490
gene id: 1071382:KAFR_0G00490
uniprot id: H2AXI2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G00480
gene id: 1071382:KAFR_0G00480
uniprot id: H2AXI1
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0D03940
gene id: 1071382:KAFR_0D03940
uniprot id: H2AUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0F01620
gene id: 1071382:KAFR_0F01620
uniprot id: H2AWK9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071382:KAFR 0E03020
gene id: 1071382:KAFR_0E03020
uniprot id: H2AVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0A03770
gene id: 1071382:KAFR_0A03770
uniprot id: H2AN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0B03650
gene id: 1071382:KAFR_0B03650
uniprot id: H2AQL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1071382:KAFR 0D04030
gene id: 1071382:KAFR_0D04030
uniprot id: H2AUK1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

1071382:KAFR 0D04200
gene id: 1071382:KAFR_0D04200
uniprot id: H2AUL8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

1071382:KAFR 0I01760
gene id: 1071382:KAFR_0I01760
uniprot id: H2B007
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

1071382:KAFR 0B03380
gene id: 1071382:KAFR_0B03380
uniprot id: H2AQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

1071382:KAFR 0E00590
gene id: 1071382:KAFR_0E00590
uniprot id: H2AV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

1071382:KAFR 0C01970
gene id: 1071382:KAFR_0C01970
uniprot id: H2AS40
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K02270
gene id: 1071382:KAFR_0K02270
uniprot id: H2B1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

1071382:KAFR 0D04040
gene id: 1071382:KAFR_0D04040
uniprot id: H2AUK2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D01820
gene id: 1071382:KAFR_0D01820
uniprot id: H2ATX9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L01510
gene id: 1071382:KAFR_0L01510
uniprot id: H2B2B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071382:KAFR 0B02290
gene id: 1071382:KAFR_0B02290
uniprot id: H2AQ77
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1071382:KAFR 0I01580
gene id: 1071382:KAFR_0I01580
uniprot id: H2AZY9
names: Similarity
messages: Belongs to the actin family.

1071382:KAFR 0C03110
gene id: 1071382:KAFR_0C03110
uniprot id: H2ASF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071382:KAFR 0B03080
gene id: 1071382:KAFR_0B03080
uniprot id: H2AQF4
names: Similarity
messages: Belongs to the NXF family.

1071382:KAFR 0K00190
gene id: 1071382:KAFR_0K00190
uniprot id: H2B174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

1071382:KAFR 0I02250
gene id: 1071382:KAFR_0I02250
uniprot id: H2B054
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C01650
gene id: 1071382:KAFR_0C01650
uniprot id: H2AS08
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A06100
gene id: 1071382:KAFR_0A06100
uniprot id: H2ANU5
names: Similarity
messages: Belongs to the FBPase class 1 family.

1071382:KAFR 0K00100
gene id: 1071382:KAFR_0K00100
uniprot id: H2B164
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G00210
gene id: 1071382:KAFR_0G00210
uniprot id: H2AXF4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A04780
gene id: 1071382:KAFR_0A04780
uniprot id: H2ANG3
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

1071382:KAFR 0A07830
gene id: 1071382:KAFR_0A07830
uniprot id: H2APB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

1071382:KAFR 0J02460
gene id: 1071382:KAFR_0J02460
uniprot id: H2B110
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

1071382:KAFR 0J01410
gene id: 1071382:KAFR_0J01410
uniprot id: H2B0Q8
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1071382:KAFR 0B00800
gene id: 1071382:KAFR_0B00800
uniprot id: H2APS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B06050
gene id: 1071382:KAFR_0B06050
uniprot id: H2ARA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

1071382:KAFR 0K00660
gene id: 1071382:KAFR_0K00660
uniprot id: H2B1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

1071382:KAFR 0K01570
gene id: 1071382:KAFR_0K01570
uniprot id: H2B1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071382:KAFR 0E00510
gene id: 1071382:KAFR_0E00510
uniprot id: H2AV05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

1071382:KAFR 0E02850
gene id: 1071382:KAFR_0E02850
uniprot id: H2AVN7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0F03650
gene id: 1071382:KAFR_0F03650
uniprot id: H2AX61
names: Similarity
messages: Belongs to the isochorismatase family.

1071382:KAFR 0E00830
gene id: 1071382:KAFR_0E00830
uniprot id: H2AV37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

1071382:KAFR 0E01920
gene id: 1071382:KAFR_0E01920
uniprot id: H2AVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071382:KAFR 0L00680
gene id: 1071382:KAFR_0L00680
uniprot id: H2B225
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C02950
gene id: 1071382:KAFR_0C02950
uniprot id: H2ASD8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

1071382:KAFR 0E03920
gene id: 1071382:KAFR_0E03920
uniprot id: H2AVZ3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1071382:KAFR 0K02560
gene id: 1071382:KAFR_0K02560
uniprot id: H2B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

1071382:KAFR 0G02010
gene id: 1071382:KAFR_0G02010
uniprot id: H2AXY5
names: Similarity
messages: Belongs to the NOC2 family.

1071382:KAFR 0B01520
gene id: 1071382:KAFR_0B01520
uniprot id: H2AQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

1071382:KAFR 0C02150
gene id: 1071382:KAFR_0C02150
uniprot id: H2AS58
names: Similarity
messages: Belongs to the MAD1 family.

1071382:KAFR 0E01750
gene id: 1071382:KAFR_0E01750
uniprot id: H2AVC9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1071382:KAFR 0I02260
gene id: 1071382:KAFR_0I02260
uniprot id: H2B055
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

1071382:KAFR 0G02960
gene id: 1071382:KAFR_0G02960
uniprot id: H2AY78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

1071382:KAFR 0L00400
gene id: 1071382:KAFR_0L00400
uniprot id: H2B1Z7
names: Similarity
messages: Belongs to the UPF0507 family.

1071382:KAFR 0H02450
gene id: 1071382:KAFR_0H02450
uniprot id: H2AZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

1071382:KAFR 0D02020
gene id: 1071382:KAFR_0D02020
uniprot id: H2ATZ9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1071382:KAFR 0L00470
gene id: 1071382:KAFR_0L00470
uniprot id: H2B204
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071382:KAFR 0J00850
gene id: 1071382:KAFR_0J00850
uniprot id: H2B0K3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1071382:KAFR 0A02010
gene id: 1071382:KAFR_0A02010
uniprot id: H2AMN9
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

1071382:KAFR 0A00580
gene id: 1071382:KAFR_0A00580
uniprot id: H2AM96
names: Function
names: Similarity
messages: Belongs to the SPG4 family.
messages: Stationary phase-essential protein not required for growth on nonfermentable carbon sources.

1071382:KAFR 0C04690
gene id: 1071382:KAFR_0C04690
uniprot id: H2ASW0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0F02280
gene id: 1071382:KAFR_0F02280
uniprot id: H2AWS5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071382:KAFR 0E03500
gene id: 1071382:KAFR_0E03500
uniprot id: H2AVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0C05490
gene id: 1071382:KAFR_0C05490
uniprot id: H2AT40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

1071382:KAFR 0G02190
gene id: 1071382:KAFR_0G02190
uniprot id: H2AY03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1071382:KAFR 0H00860
gene id: 1071382:KAFR_0H00860
uniprot id: H2AYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0G01260
gene id: 1071382:KAFR_0G01260
uniprot id: H2AXR0
names: Similarity
messages: Belongs to the hexokinase family.

1071382:KAFR 0D02090
gene id: 1071382:KAFR_0D02090
uniprot id: H2AU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0B00580
gene id: 1071382:KAFR_0B00580
uniprot id: H2APQ7
names: Similarity
messages: Belongs to the yippee family.

1071382:KAFR 0H02040
gene id: 1071382:KAFR_0H02040
uniprot id: H2AZ57
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J01030
gene id: 1071382:KAFR_0J01030
uniprot id: H2B0M1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K01770
gene id: 1071382:KAFR_0K01770
uniprot id: H2B1N1
names: Similarity
messages: Belongs to the RICTOR family.

1071382:KAFR 0F02820
gene id: 1071382:KAFR_0F02820
uniprot id: H2AWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

1071382:KAFR 0D02610
gene id: 1071382:KAFR_0D02610
uniprot id: H2AU58
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071382:KAFR 0E03670
gene id: 1071382:KAFR_0E03670
uniprot id: H2AVW8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1071382:KAFR 0B01820
gene id: 1071382:KAFR_0B01820
uniprot id: H2AQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

1071382:KAFR 0B01800
gene id: 1071382:KAFR_0B01800
uniprot id: H2AQ29
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E04370
gene id: 1071382:KAFR_0E04370
uniprot id: H2AW37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1071382:KAFR 0B04550
gene id: 1071382:KAFR_0B04550
uniprot id: H2AQV2
names: Similarity
messages: Belongs to the cytochrome b5 family.

1071382:KAFR 0A00140
gene id: 1071382:KAFR_0A00140
uniprot id: H2AM52
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071382:KAFR 0H01050
gene id: 1071382:KAFR_0H01050
uniprot id: H2AYV9
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

1071382:KAFR 0E01960
gene id: 1071382:KAFR_0E01960
uniprot id: H2AVF0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1071382:KAFR 0I01670
gene id: 1071382:KAFR_0I01670
uniprot id: H2AZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

1071382:KAFR 0D04750
gene id: 1071382:KAFR_0D04750
uniprot id: H2AUS2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B05470
gene id: 1071382:KAFR_0B05470
uniprot id: H2AR42
names: Similarity
messages: Belongs to the eIF2D family.

1071382:KAFR 0D04340
gene id: 1071382:KAFR_0D04340
uniprot id: H2AUN2
names: Similarity
messages: Belongs to the TCF25 family.

1071382:KAFR 0I01200
gene id: 1071382:KAFR_0I01200
uniprot id: H2AZV1
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

1071382:KAFR 0D00690
gene id: 1071382:KAFR_0D00690
uniprot id: H2ATL6
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0F01360
gene id: 1071382:KAFR_0F01360
uniprot id: H2AWI2
names: Similarity
messages: Belongs to the PET191 family.

1071382:KAFR 0J01280
gene id: 1071382:KAFR_0J01280
uniprot id: H2B0P5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0C00230
gene id: 1071382:KAFR_0C00230
uniprot id: H2ARL9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

1071382:KAFR 0B06630
gene id: 1071382:KAFR_0B06630
uniprot id: H2ARG0
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1071382:KAFR 0J00170
gene id: 1071382:KAFR_0J00170
uniprot id: H2B0D5
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071382:KAFR 0A02870
gene id: 1071382:KAFR_0A02870
uniprot id: H2AMX3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071382:KAFR 0I01510
gene id: 1071382:KAFR_0I01510
uniprot id: H2AZY2
names: Similarity
messages: Belongs to the FGGY kinase family.

1071382:KAFR 0J01910
gene id: 1071382:KAFR_0J01910
uniprot id: H2B0V5
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

1071382:KAFR 0A04660
gene id: 1071382:KAFR_0A04660
uniprot id: H2ANF1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1071382:KAFR 0J02480
gene id: 1071382:KAFR_0J02480
uniprot id: H2B112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D04960
gene id: 1071382:KAFR_0D04960
uniprot id: H2AUU3
names: Subcellular Location Annotation
messages: Golgi apparatus

1071382:KAFR 0B06910
gene id: 1071382:KAFR_0B06910
uniprot id: H2ARI8
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

1071382:KAFR 0D04220
gene id: 1071382:KAFR_0D04220
uniprot id: H2AUM0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0H01320
gene id: 1071382:KAFR_0H01320
uniprot id: H2AYY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus membrane

1071382:KAFR 0B02510
gene id: 1071382:KAFR_0B02510
uniprot id: H2AQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071382:KAFR 0G02770
gene id: 1071382:KAFR_0G02770
uniprot id: H2AY58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

1071382:KAFR 0L01270
gene id: 1071382:KAFR_0L01270
uniprot id: H2B286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

1071382:KAFR 0D02170
gene id: 1071382:KAFR_0D02170
uniprot id: H2AU14
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1071382:KAFR 0H01680
gene id: 1071382:KAFR_0H01680
uniprot id: H2AZ22
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1071382:KAFR 0A04860
gene id: 1071382:KAFR_0A04860
uniprot id: H2AY25
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

1071382:KAFR 0A04320
gene id: 1071382:KAFR_0A04320
uniprot id: H2ANB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

1071382:KAFR 0B00760
gene id: 1071382:KAFR_0B00760
uniprot id: H2APS4
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1071382:KAFR 0J02010
gene id: 1071382:KAFR_0J02010
uniprot id: H2B0W5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

1071382:KAFR 0E02450
gene id: 1071382:KAFR_0E02450
uniprot id: H2AVJ8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071382:KAFR 0C02920
gene id: 1071382:KAFR_0C02920
uniprot id: H2ASD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1071382:KAFR 0F01600
gene id: 1071382:KAFR_0F01600
uniprot id: H2AWK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SOP4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
messages: Membrane

1071382:KAFR 0E04430
gene id: 1071382:KAFR_0E04430
uniprot id: H2AW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

1071382:KAFR 0A02890
gene id: 1071382:KAFR_0A02890
uniprot id: H2AMX5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1071382:KAFR 0B01780
gene id: 1071382:KAFR_0B01780
uniprot id: H2AQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

1071382:KAFR 0A08390
gene id: 1071382:KAFR_0A08390
uniprot id: H2APH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

1071382:KAFR 0H01130
gene id: 1071382:KAFR_0H01130
uniprot id: H2AYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

1071382:KAFR 0I00950
gene id: 1071382:KAFR_0I00950
uniprot id: H2AZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

1071382:KAFR 0C01740
gene id: 1071382:KAFR_0C01740
uniprot id: H2AS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1071382:KAFR 0G01590
gene id: 1071382:KAFR_0G01590
uniprot id: H2AXU3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

1071382:KAFR 0B04390
gene id: 1071382:KAFR_0B04390
uniprot id: H2AQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

1071382:KAFR 0K02380
gene id: 1071382:KAFR_0K02380
uniprot id: H2B1U3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B00790
gene id: 1071382:KAFR_0B00790
uniprot id: H2APS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0A07460
gene id: 1071382:KAFR_0A07460
uniprot id: H2AP80
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

1071382:KAFR 0B02960
gene id: 1071382:KAFR_0B02960
uniprot id: H2AQE2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1071382:KAFR 0I00690
gene id: 1071382:KAFR_0I00690
uniprot id: H2AZQ0
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

1071382:KAFR 0G03070
gene id: 1071382:KAFR_0G03070
uniprot id: H2AY89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1071382:KAFR 0K01670
gene id: 1071382:KAFR_0K01670
uniprot id: H2B1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0D01310
gene id: 1071382:KAFR_0D01310
uniprot id: H2ATS7
names: Similarity
messages: Belongs to the OPI10 family.

1071382:KAFR 0A05500
gene id: 1071382:KAFR_0A05500
uniprot id: H2ANN5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0E04470
gene id: 1071382:KAFR_0E04470
uniprot id: H2AW47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1071382:KAFR 0C06310
gene id: 1071382:KAFR_0C06310
uniprot id: H2ATC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

1071382:KAFR 0G02510
gene id: 1071382:KAFR_0G02510
uniprot id: H2AY34
names: Similarity
messages: Belongs to the HIT family.

1071382:KAFR 0I00430
gene id: 1071382:KAFR_0I00430
uniprot id: H2AZM4
names: Similarity
messages: Belongs to the type-1 OGG1 family.

1071382:KAFR 0K01290
gene id: 1071382:KAFR_0K01290
uniprot id: H2B1I3
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071382:KAFR 0B05120
gene id: 1071382:KAFR_0B05120
uniprot id: H2AR08
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C06440
gene id: 1071382:KAFR_0C06440
uniprot id: H2ATE0
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1071382:KAFR 0B03740
gene id: 1071382:KAFR_0B03740
uniprot id: H2AQM0
names: Similarity
messages: Belongs to the SAP30 family.

1071382:KAFR 0A02750
gene id: 1071382:KAFR_0A02750
uniprot id: H2AMW1
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0F00650
gene id: 1071382:KAFR_0F00650
uniprot id: H2AWB2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E02210
gene id: 1071382:KAFR_0E02210
uniprot id: H2AVH4
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1071382:KAFR 0G02380
gene id: 1071382:KAFR_0G02380
uniprot id: H2AY22
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071382:KAFR 0L01440
gene id: 1071382:KAFR_0L01440
uniprot id: H2B2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: nuclear pore complex

1071382:KAFR 0H01840
gene id: 1071382:KAFR_0H01840
uniprot id: H2AZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0J02680
gene id: 1071382:KAFR_0J02680
uniprot id: H2B132
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1071382:KAFR 0C05360
gene id: 1071382:KAFR_0C05360
uniprot id: H2AT27
names: Similarity
messages: Belongs to the AFG1 ATPase family.

1071382:KAFR 0C06020
gene id: 1071382:KAFR_0C06020
uniprot id: H2AT93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1071382:KAFR 0H02690
gene id: 1071382:KAFR_0H02690
uniprot id: H2AZC2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1071382:KAFR 0D02000
gene id: 1071382:KAFR_0D02000
uniprot id: H2ATZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071382:KAFR 0E00210
gene id: 1071382:KAFR_0E00210
uniprot id: H2AUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0C03890
gene id: 1071382:KAFR_0C03890
uniprot id: H2ASN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

1071382:KAFR 0B01270
gene id: 1071382:KAFR_0B01270
uniprot id: H2APX6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1071382:KAFR 0L00170
gene id: 1071382:KAFR_0L00170
uniprot id: H2B1X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.

1071382:KAFR 0B06900
gene id: 1071382:KAFR_0B06900
uniprot id: H2ARI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

1071382:KAFR 0F04330
gene id: 1071382:KAFR_0F04330
uniprot id: H2AXC8
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1071382:KAFR 0E01130
gene id: 1071382:KAFR_0E01130
uniprot id: H2AV67
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1071382:KAFR 0I02450
gene id: 1071382:KAFR_0I02450
uniprot id: H2B074
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1071382:KAFR 0A02910
gene id: 1071382:KAFR_0A02910
uniprot id: H2AMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0C03400
gene id: 1071382:KAFR_0C03400
uniprot id: H2ASI2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

1071382:KAFR 0C01910
gene id: 1071382:KAFR_0C01910
uniprot id: H2AS34
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C00810
gene id: 1071382:KAFR_0C00810
uniprot id: H2ARS6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1071382:KAFR 0H00880
gene id: 1071382:KAFR_0H00880
uniprot id: H2AYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

1071382:KAFR 0A00820
gene id: 1071382:KAFR_0A00820
uniprot id: H2AMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0J02130
gene id: 1071382:KAFR_0J02130
uniprot id: H2B0X7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L00840
gene id: 1071382:KAFR_0L00840
uniprot id: H2B242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0B04760
gene id: 1071382:KAFR_0B04760
uniprot id: H2AQX3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1071382:KAFR 0E04390
gene id: 1071382:KAFR_0E04390
uniprot id: H2AW39
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1071382:KAFR 0C04970
gene id: 1071382:KAFR_0C04970
uniprot id: H2ASY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071382:KAFR 0K00670
gene id: 1071382:KAFR_0K00670
uniprot id: H2B1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D02350
gene id: 1071382:KAFR_0D02350
uniprot id: H2AU32
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C03490
gene id: 1071382:KAFR_0C03490
uniprot id: H2ASJ1
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071382:KAFR 0J01740
gene id: 1071382:KAFR_0J01740
uniprot id: H2B0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0I01490
gene id: 1071382:KAFR_0I01490
uniprot id: H2AZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

1071382:KAFR 0L00180
gene id: 1071382:KAFR_0L00180
uniprot id: H2B1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

1071382:KAFR 0G01290
gene id: 1071382:KAFR_0G01290
uniprot id: H2AXR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1071382:KAFR 0F01350
gene id: 1071382:KAFR_0F01350
uniprot id: H2AWI1
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C04470
gene id: 1071382:KAFR_0C04470
uniprot id: H2AST8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

1071382:KAFR 0J00290
gene id: 1071382:KAFR_0J00290
uniprot id: H2B0E7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1071382:KAFR 0A01310
gene id: 1071382:KAFR_0A01310
uniprot id: H2AMG9
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0I00490
gene id: 1071382:KAFR_0I00490
uniprot id: H2AZN0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1071382:KAFR 0D03610
gene id: 1071382:KAFR_0D03610
uniprot id: H2AUF9
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

1071382:KAFR 0H03400
gene id: 1071382:KAFR_0H03400
uniprot id: H2AYH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

1071382:KAFR 0F00700
gene id: 1071382:KAFR_0F00700
uniprot id: H2AWB7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

1071382:KAFR 0A01630
gene id: 1071382:KAFR_0A01630
uniprot id: H2AMK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

1071382:KAFR 0B05250
gene id: 1071382:KAFR_0B05250
uniprot id: H2AR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

1071382:KAFR 0B05300
gene id: 1071382:KAFR_0B05300
uniprot id: H2AR25
names: Similarity
messages: Belongs to the 14-3-3 family.

1071382:KAFR 0B00890
gene id: 1071382:KAFR_0B00890
uniprot id: H2APT7
names: Similarity
messages: Belongs to the epsin family.

1071382:KAFR 0G02240
gene id: 1071382:KAFR_0G02240
uniprot id: H2AY08
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1071382:KAFR 0D04390
gene id: 1071382:KAFR_0D04390
uniprot id: H2AUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

1071382:KAFR 0G00740
gene id: 1071382:KAFR_0G00740
uniprot id: H2AXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

1071382:KAFR 0B05980
gene id: 1071382:KAFR_0B05980
uniprot id: H2AR94
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071382:KAFR 0A05700
gene id: 1071382:KAFR_0A05700
uniprot id: H2ANQ5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

1071382:KAFR 0B03930
gene id: 1071382:KAFR_0B03930
uniprot id: H2AQN9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C04930
gene id: 1071382:KAFR_0C04930
uniprot id: H2ASY4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

1071382:KAFR 0D04940
gene id: 1071382:KAFR_0D04940
uniprot id: H2AUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E03360
gene id: 1071382:KAFR_0E03360
uniprot id: H2AVT8
names: Similarity
messages: Belongs to the peptidase M28 family.

1071382:KAFR 0H01660
gene id: 1071382:KAFR_0H01660
uniprot id: H2AZ20
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0F01090
gene id: 1071382:KAFR_0F01090
uniprot id: H2AWF5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B06520
gene id: 1071382:KAFR_0B06520
uniprot id: H2ARE8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

1071382:KAFR 0F04230
gene id: 1071382:KAFR_0F04230
uniprot id: H2AXB8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071382:KAFR 0E04120
gene id: 1071382:KAFR_0E04120
uniprot id: H2AW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0F03310
gene id: 1071382:KAFR_0F03310
uniprot id: H2AX27
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

1071382:KAFR 0C01990
gene id: 1071382:KAFR_0C01990
uniprot id: H2AS42
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0F02580
gene id: 1071382:KAFR_0F02580
uniprot id: H2AWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

1071382:KAFR 0A08730
gene id: 1071382:KAFR_0A08730
uniprot id: H2APK7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0A05050
gene id: 1071382:KAFR_0A05050
uniprot id: H2ANJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

1071382:KAFR 0A06700
gene id: 1071382:KAFR_0A06700
uniprot id: H2AP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1071382:KAFR 0E01310
gene id: 1071382:KAFR_0E01310
uniprot id: H2AV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0G01140
gene id: 1071382:KAFR_0G01140
uniprot id: H2AXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

1071382:KAFR 0B06450
gene id: 1071382:KAFR_0B06450
uniprot id: H2ARE1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

1071382:KAFR 0F03570
gene id: 1071382:KAFR_0F03570
uniprot id: H2AX53
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1071382:KAFR 0A05220
gene id: 1071382:KAFR_0A05220
uniprot id: H2ANK7
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0C04260
gene id: 1071382:KAFR_0C04260
uniprot id: H2ASR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).

1071382:KAFR 0A05450
gene id: 1071382:KAFR_0A05450
uniprot id: H2ANN0
names: Function
names: Similarity
messages: Belongs to the RRG8 family.
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

1071382:KAFR 0J00910
gene id: 1071382:KAFR_0J00910
uniprot id: H2B0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

1071382:KAFR 0J00620
gene id: 1071382:KAFR_0J00620
uniprot id: H2B0I0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071382:KAFR 0E00250
gene id: 1071382:KAFR_0E00250
uniprot id: H2AUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

1071382:KAFR 0B06070
gene id: 1071382:KAFR_0B06070
uniprot id: H2ARA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A00310
gene id: 1071382:KAFR_0A00310
uniprot id: H2AM69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

1071382:KAFR 0E04010
gene id: 1071382:KAFR_0E04010
uniprot id: H2AW02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC110 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.
messages: Nucleus
messages: spindle pole body

1071382:KAFR 0E03330
gene id: 1071382:KAFR_0E03330
uniprot id: H2AVT5
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B01250
gene id: 1071382:KAFR_0B01250
uniprot id: H2APX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071382:KAFR 0E03180
gene id: 1071382:KAFR_0E03180
uniprot id: H2AVS0
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

1071382:KAFR 0C05060
gene id: 1071382:KAFR_0C05060
uniprot id: H2ASZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071382:KAFR 0C03210
gene id: 1071382:KAFR_0C03210
uniprot id: H2ASG3
names: Similarity
messages: Belongs to the BLM10 family.

1071382:KAFR 0G03620
gene id: 1071382:KAFR_0G03620
uniprot id: H2AYE4
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

1071382:KAFR 0K02250
gene id: 1071382:KAFR_0K02250
uniprot id: H2B1S9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1071382:KAFR 0E03280
gene id: 1071382:KAFR_0E03280
uniprot id: H2AVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

1071382:KAFR 0I01500
gene id: 1071382:KAFR_0I01500
uniprot id: H2AZY1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L01710
gene id: 1071382:KAFR_0L01710
uniprot id: H2B2D1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071382:KAFR 0H01530
gene id: 1071382:KAFR_0H01530
uniprot id: H2AZ07
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0A02580
gene id: 1071382:KAFR_0A02580
uniprot id: H2AMU4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I00810
gene id: 1071382:KAFR_0I00810
uniprot id: H2AZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F01700
gene id: 1071382:KAFR_0F01700
uniprot id: H2AWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

1071382:KAFR 0A01560
gene id: 1071382:KAFR_0A01560
uniprot id: H2AMJ4
names: Similarity
messages: Belongs to the actin family.

1071382:KAFR 0C00620
gene id: 1071382:KAFR_0C00620
uniprot id: H2ARQ7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071382:KAFR 0J00610
gene id: 1071382:KAFR_0J00610
uniprot id: H2B0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

1071382:KAFR 0E01940
gene id: 1071382:KAFR_0E01940
uniprot id: H2AVE8
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1071382:KAFR 0B04770
gene id: 1071382:KAFR_0B04770
uniprot id: H2AQX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

1071382:KAFR 0G00380
gene id: 1071382:KAFR_0G00380
uniprot id: H2AXH1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C05070
gene id: 1071382:KAFR_0C05070
uniprot id: H2ASZ8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1071382:KAFR 0F02120
gene id: 1071382:KAFR_0F02120
uniprot id: H2AWQ9
names: Similarity
messages: Belongs to the SF3A2 family.

1071382:KAFR 0A04480
gene id: 1071382:KAFR_0A04480
uniprot id: H2AND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

1071382:KAFR 0A05610
gene id: 1071382:KAFR_0A05610
uniprot id: H2ANP6
names: Similarity
messages: Belongs to the WD repeat coronin family.

1071382:KAFR 0A08010
gene id: 1071382:KAFR_0A08010
uniprot id: H2APD5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0D04630
gene id: 1071382:KAFR_0D04630
uniprot id: H2AUR1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

1071382:KAFR 0F03780
gene id: 1071382:KAFR_0F03780
uniprot id: H2AX74
names: Similarity
messages: Belongs to the AAA ATPase family.

1071382:KAFR 0A01180
gene id: 1071382:KAFR_0A01180
uniprot id: H2AMF7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I00360
gene id: 1071382:KAFR_0I00360
uniprot id: H2AZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071382:KAFR 0A01400
gene id: 1071382:KAFR_0A01400
uniprot id: H2AMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B02430
gene id: 1071382:KAFR_0B02430
uniprot id: H2AQ91
names: Similarity
messages: Belongs to the COG3 family.

1071382:KAFR 0L01820
gene id: 1071382:KAFR_0L01820
uniprot id: H2B2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071382:KAFR 0K00890
gene id: 1071382:KAFR_0K00890
uniprot id: H2B1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0B02350
gene id: 1071382:KAFR_0B02350
uniprot id: H2AQ83
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0F03300
gene id: 1071382:KAFR_0F03300
uniprot id: H2AX26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071382:KAFR 0L02000
gene id: 1071382:KAFR_0L02000
uniprot id: H2B2G1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0B06550
gene id: 1071382:KAFR_0B06550
uniprot id: H2ARF1
names: Similarity
messages: Belongs to the peptidase S8 family.

1071382:KAFR 0E03050
gene id: 1071382:KAFR_0E03050
uniprot id: H2AVQ7
names: Similarity
messages: Belongs to the PGA52 family.

1071382:KAFR 0B06560
gene id: 1071382:KAFR_0B06560
uniprot id: H2ARF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0H03050
gene id: 1071382:KAFR_0H03050
uniprot id: H2AZF9
names: Similarity
messages: Belongs to the citrate synthase family.

1071382:KAFR 0G00730
gene id: 1071382:KAFR_0G00730
uniprot id: H2AXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

1071382:KAFR 0J01810
gene id: 1071382:KAFR_0J01810
uniprot id: H2B0U5
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

1071382:KAFR 0J00100
gene id: 1071382:KAFR_0J00100
uniprot id: H2B0C8
names: Similarity
messages: Belongs to the arginase family.

1071382:KAFR 0E04040
gene id: 1071382:KAFR_0E04040
uniprot id: H2AW05
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C02470
gene id: 1071382:KAFR_0C02470
uniprot id: H2AS90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D03370
gene id: 1071382:KAFR_0D03370
uniprot id: H2AUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1071382:KAFR 0A04770
gene id: 1071382:KAFR_0A04770
uniprot id: H2ANG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071382:KAFR 0I02840
gene id: 1071382:KAFR_0I02840
uniprot id: H2B0B3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

1071382:KAFR 0A03260
gene id: 1071382:KAFR_0A03260
uniprot id: H2AN11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

1071382:KAFR 0G03040
gene id: 1071382:KAFR_0G03040
uniprot id: H2AY86
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071382:KAFR 0E01700
gene id: 1071382:KAFR_0E01700
uniprot id: H2AVC4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071382:KAFR 0A02520
gene id: 1071382:KAFR_0A02520
uniprot id: H2AMT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

1071382:KAFR 0J01670
gene id: 1071382:KAFR_0J01670
uniprot id: H2B0T2
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071382:KAFR 0I02500
gene id: 1071382:KAFR_0I02500
uniprot id: H2B079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071382:KAFR 0B06770
gene id: 1071382:KAFR_0B06770
uniprot id: H2ARH4
names: Similarity
messages: Belongs to the NAD kinase family.

1071382:KAFR 0H00420
gene id: 1071382:KAFR_0H00420
uniprot id: H2AYP5
names: Similarity
messages: Belongs to the SGT1 family.

1071382:KAFR 0J02860
gene id: 1071382:KAFR_0J02860
uniprot id: H2B150
names: Similarity
messages: Belongs to the APC10 family.

1071382:KAFR 0B05720
gene id: 1071382:KAFR_0B05720
uniprot id: H2AR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

1071382:KAFR 0K02320
gene id: 1071382:KAFR_0K02320
uniprot id: H2B1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

1071382:KAFR 0H00170
gene id: 1071382:KAFR_0H00170
uniprot id: H2AYM0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01120
gene id: 1071382:KAFR_0H01120
uniprot id: H2AYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

1071382:KAFR 0D03930
gene id: 1071382:KAFR_0D03930
uniprot id: H2AUJ1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071382:KAFR 0K00630
gene id: 1071382:KAFR_0K00630
uniprot id: H2B1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071382:KAFR 0C05440
gene id: 1071382:KAFR_0C05440
uniprot id: H2AT35
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1071382:KAFR 0A07010
gene id: 1071382:KAFR_0A07010
uniprot id: H2AP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071382:KAFR 0A03480
gene id: 1071382:KAFR_0A03480
uniprot id: H2AN33
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

1071382:KAFR 0B04520
gene id: 1071382:KAFR_0B04520
uniprot id: H2AQU9
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071382:KAFR 0J02810
gene id: 1071382:KAFR_0J02810
uniprot id: H2B145
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071382:KAFR 0F04070
gene id: 1071382:KAFR_0F04070
uniprot id: H2AXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

1071382:KAFR 0E02710
gene id: 1071382:KAFR_0E02710
uniprot id: H2AVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

1071382:KAFR 0G00650
gene id: 1071382:KAFR_0G00650
uniprot id: H2AXJ8
names: Function
names: Similarity
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

1071382:KAFR 0H01430
gene id: 1071382:KAFR_0H01430
uniprot id: H2AYZ7
names: Similarity
messages: Belongs to the SKP1 family.

1071382:KAFR 0I01100
gene id: 1071382:KAFR_0I01100
uniprot id: H2AZU1
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

1071382:KAFR 0A08020
gene id: 1071382:KAFR_0A08020
uniprot id: H2APD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0E02720
gene id: 1071382:KAFR_0E02720
uniprot id: H2AVM4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A02180
gene id: 1071382:KAFR_0A02180
uniprot id: H2AMQ6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

1071382:KAFR 0J02840
gene id: 1071382:KAFR_0J02840
uniprot id: H2B148
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

1071382:KAFR 0L00380
gene id: 1071382:KAFR_0L00380
uniprot id: H2B1Z5
names: Similarity
messages: Belongs to the NPR2 family.

1071382:KAFR 0A02300
gene id: 1071382:KAFR_0A02300
uniprot id: H2AMR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0C01870
gene id: 1071382:KAFR_0C01870
uniprot id: H2AS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

1071382:KAFR 0E01730
gene id: 1071382:KAFR_0E01730
uniprot id: H2AVC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

1071382:KAFR 0L01970
gene id: 1071382:KAFR_0L01970
uniprot id: H2B2F8
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1071382:KAFR 0A05310
gene id: 1071382:KAFR_0A05310
uniprot id: H2ANL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0F00370
gene id: 1071382:KAFR_0F00370
uniprot id: H2AW84
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

1071382:KAFR 0B04290
gene id: 1071382:KAFR_0B04290
uniprot id: H2AQS5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071382:KAFR 0B03620
gene id: 1071382:KAFR_0B03620
uniprot id: H2AQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

1071382:KAFR 0A03840
gene id: 1071382:KAFR_0A03840
uniprot id: H2AN69
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1071382:KAFR 0D00170
gene id: 1071382:KAFR_0D00170
uniprot id: H2ATG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B06940
gene id: 1071382:KAFR_0B06940
uniprot id: H2ARJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

1071382:KAFR 0D02790
gene id: 1071382:KAFR_0D02790
uniprot id: H2AU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071382:KAFR 0L01230
gene id: 1071382:KAFR_0L01230
uniprot id: H2B281
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071382:KAFR 0D00780
gene id: 1071382:KAFR_0D00780
uniprot id: H2ATM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0A05680
gene id: 1071382:KAFR_0A05680
uniprot id: H2ANQ3
names: Similarity
messages: Belongs to the DOCK family.

1071382:KAFR 0A00150
gene id: 1071382:KAFR_0A00150
uniprot id: H2AM53
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0F04360
gene id: 1071382:KAFR_0F04360
uniprot id: H2AXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

1071382:KAFR 0B05970
gene id: 1071382:KAFR_0B05970
uniprot id: H2AR93
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E00780
gene id: 1071382:KAFR_0E00780
uniprot id: H2AV32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

1071382:KAFR 0C04530
gene id: 1071382:KAFR_0C04530
uniprot id: H2ASU4
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1071382:KAFR 0C00440
gene id: 1071382:KAFR_0C00440
uniprot id: H2ARN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

1071382:KAFR 0E01770
gene id: 1071382:KAFR_0E01770
uniprot id: H2AVD1
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

1071382:KAFR 0C03750
gene id: 1071382:KAFR_0C03750
uniprot id: H2ASL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0G02850
gene id: 1071382:KAFR_0G02850
uniprot id: H2AY67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

1071382:KAFR 0A03000
gene id: 1071382:KAFR_0A03000
uniprot id: H2AMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

1071382:KAFR 0D02580
gene id: 1071382:KAFR_0D02580
uniprot id: H2AU55
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0A06490
gene id: 1071382:KAFR_0A06490
uniprot id: H2ANY4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A06240
gene id: 1071382:KAFR_0A06240
uniprot id: H2ANV9
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B03490
gene id: 1071382:KAFR_0B03490
uniprot id: H2AQJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1071382:KAFR 0B01080
gene id: 1071382:KAFR_0B01080
uniprot id: H2APV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0B02110
gene id: 1071382:KAFR_0B02110
uniprot id: H2AQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

1071382:KAFR 0J02020
gene id: 1071382:KAFR_0J02020
uniprot id: H2B0W6
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071382:KAFR 0A00950
gene id: 1071382:KAFR_0A00950
uniprot id: H2AMD3
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1071382:KAFR 0E01710
gene id: 1071382:KAFR_0E01710
uniprot id: H2AVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

1071382:KAFR 0D04330
gene id: 1071382:KAFR_0D04330
uniprot id: H2AUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1071382:KAFR 0H02560
gene id: 1071382:KAFR_0H02560
uniprot id: H2AZA9
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L00440
gene id: 1071382:KAFR_0L00440
uniprot id: H2B201
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

1071382:KAFR 0B03350
gene id: 1071382:KAFR_0B03350
uniprot id: H2AQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

1071382:KAFR 0E02730
gene id: 1071382:KAFR_0E02730
uniprot id: H2AVM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

1071382:KAFR 0C01230
gene id: 1071382:KAFR_0C01230
uniprot id: H2ARW8
names: Similarity
messages: Belongs to the SIN1 family.

1071382:KAFR 0G01420
gene id: 1071382:KAFR_0G01420
uniprot id: H2AXS6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0K01860
gene id: 1071382:KAFR_0K01860
uniprot id: H2B1P0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0L00620
gene id: 1071382:KAFR_0L00620
uniprot id: H2B219
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

1071382:KAFR 0C03560
gene id: 1071382:KAFR_0C03560
uniprot id: H2ASJ8
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071382:KAFR 0H02620
gene id: 1071382:KAFR_0H02620
uniprot id: H2AZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

1071382:KAFR 0K02040
gene id: 1071382:KAFR_0K02040
uniprot id: H2B1Q8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1071382:KAFR 0E02840
gene id: 1071382:KAFR_0E02840
uniprot id: H2AVN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1071382:KAFR 0L00750
gene id: 1071382:KAFR_0L00750
uniprot id: H2B232
names: Similarity
messages: Belongs to the complex I LYR family.

1071382:KAFR 0L00230
gene id: 1071382:KAFR_0L00230
uniprot id: H2B1Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1071382:KAFR 0K00320
gene id: 1071382:KAFR_0K00320
uniprot id: H2B187
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0A07750
gene id: 1071382:KAFR_0A07750
uniprot id: H2APA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTT106 family.
messages: Nucleus

1071382:KAFR 0C06090
gene id: 1071382:KAFR_0C06090
uniprot id: H2ATA0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0H02160
gene id: 1071382:KAFR_0H02160
uniprot id: H2AZ69
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

1071382:KAFR 0H01080
gene id: 1071382:KAFR_0H01080
uniprot id: H2AYW2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1071382:KAFR 0B04020
gene id: 1071382:KAFR_0B04020
uniprot id: H2AQP8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1071382:KAFR 0H03470
gene id: 1071382:KAFR_0H03470
uniprot id: H2AYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

1071382:KAFR 0K00920
gene id: 1071382:KAFR_0K00920
uniprot id: H2B1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1071382:KAFR 0A04630
gene id: 1071382:KAFR_0A04630
uniprot id: H2ANE8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1071382:KAFR 0C02970
gene id: 1071382:KAFR_0C02970
uniprot id: H2ASE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0H02260
gene id: 1071382:KAFR_0H02260
uniprot id: H2AZ79
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0C03290
gene id: 1071382:KAFR_0C03290
uniprot id: H2ASH1
names: Similarity
messages: Belongs to the NEMF family.

1071382:KAFR 0L00270
gene id: 1071382:KAFR_0L00270
uniprot id: H2B1Y4
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

1071382:KAFR 0F01710
gene id: 1071382:KAFR_0F01710
uniprot id: H2AWL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1071382:KAFR 0E01680
gene id: 1071382:KAFR_0E01680
uniprot id: H2AVC2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B03220
gene id: 1071382:KAFR_0B03220
uniprot id: H2AQG8
names: Similarity
messages: Belongs to the EFR3 family.

1071382:KAFR 0A01550
gene id: 1071382:KAFR_0A01550
uniprot id: H2AMJ3
names: Similarity
messages: Belongs to the IML2 family.

1071382:KAFR 0G00400
gene id: 1071382:KAFR_0G00400
uniprot id: H2AXH3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1071382:KAFR 0H03760
gene id: 1071382:KAFR_0H03760
uniprot id: H2AYK9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0B05530
gene id: 1071382:KAFR_0B05530
uniprot id: H2AR48
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1071382:KAFR 0A02730
gene id: 1071382:KAFR_0A02730
uniprot id: H2AMV9
names: Subcellular Location Annotation
messages: nuclear pore complex

1071382:KAFR 0B04710
gene id: 1071382:KAFR_0B04710
uniprot id: H2AQW8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071382:KAFR 0A03360
gene id: 1071382:KAFR_0A03360
uniprot id: H2AN21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0G03630
gene id: 1071382:KAFR_0G03630
uniprot id: H2AYE5
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1071382:KAFR 0A03270
gene id: 1071382:KAFR_0A03270
uniprot id: H2AN12
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L01420
gene id: 1071382:KAFR_0L01420
uniprot id: H2B2A1
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0H01880
gene id: 1071382:KAFR_0H01880
uniprot id: H2AZ41
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

1071382:KAFR 0J00970
gene id: 1071382:KAFR_0J00970
uniprot id: H2B0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

1071382:KAFR 0A01720
gene id: 1071382:KAFR_0A01720
uniprot id: H2AML0
names: Subcellular Location Annotation
messages: nuclear pore complex

1071382:KAFR 0G01630
gene id: 1071382:KAFR_0G01630
uniprot id: H2AXU7
names: Similarity
messages: Belongs to the small Tim family.

1071382:KAFR 0L00850
gene id: 1071382:KAFR_0L00850
uniprot id: H2B243
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1071382:KAFR 0A05410
gene id: 1071382:KAFR_0A05410
uniprot id: H2ANM6
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0A08070
gene id: 1071382:KAFR_0A08070
uniprot id: H2APE1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

1071382:KAFR 0I02860
gene id: 1071382:KAFR_0I02860
uniprot id: H2B0B5
names: Similarity
messages: Belongs to the WD repeat RTC1 family.

1071382:KAFR 0L01280
gene id: 1071382:KAFR_0L01280
uniprot id: H2B287
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1071382:KAFR 0D04580
gene id: 1071382:KAFR_0D04580
uniprot id: H2AUQ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0C05520
gene id: 1071382:KAFR_0C05520
uniprot id: H2AT43
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B06130
gene id: 1071382:KAFR_0B06130
uniprot id: H2ARA9
names: Similarity
messages: Belongs to the phosducin family.

1071382:KAFR 0C01410
gene id: 1071382:KAFR_0C01410
uniprot id: H2ARY4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0J01650
gene id: 1071382:KAFR_0J01650
uniprot id: H2B0T0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0E00290
gene id: 1071382:KAFR_0E00290
uniprot id: H2AUY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

1071382:KAFR 0F04270
gene id: 1071382:KAFR_0F04270
uniprot id: H2AXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

1071382:KAFR 0A05430
gene id: 1071382:KAFR_0A05430
uniprot id: H2ANM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A04400
gene id: 1071382:KAFR_0A04400
uniprot id: H2ANC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B03160
gene id: 1071382:KAFR_0B03160
uniprot id: H2AQG2
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

1071382:KAFR 0C05720
gene id: 1071382:KAFR_0C05720
uniprot id: H2AT63
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071382:KAFR 0C05310
gene id: 1071382:KAFR_0C05310
uniprot id: H2AT22
names: Similarity
messages: Belongs to the PIAS family.

1071382:KAFR 0C01000
gene id: 1071382:KAFR_0C01000
uniprot id: H2ARU5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1071382:KAFR 0G03500
gene id: 1071382:KAFR_0G03500
uniprot id: H2AYD2
names: Similarity
messages: Belongs to the ERT1/acuK family.

1071382:KAFR 0H02090
gene id: 1071382:KAFR_0H02090
uniprot id: H2AZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

1071382:KAFR 0A06910
gene id: 1071382:KAFR_0A06910
uniprot id: H2AP26
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0H01360
gene id: 1071382:KAFR_0H01360
uniprot id: H2AYZ0
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

1071382:KAFR 0H01600
gene id: 1071382:KAFR_0H01600
uniprot id: H2AZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

1071382:KAFR 0I01410
gene id: 1071382:KAFR_0I01410
uniprot id: H2AZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E02310
gene id: 1071382:KAFR_0E02310
uniprot id: H2AVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1071382:KAFR 0A00930
gene id: 1071382:KAFR_0A00930
uniprot id: H2AMD1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0L01460
gene id: 1071382:KAFR_0L01460
uniprot id: H2B2A5
names: Similarity
messages: Belongs to the epsin family.

1071382:KAFR 0K02580
gene id: 1071382:KAFR_0K02580
uniprot id: H2B1W4
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071382:KAFR 0A03890
gene id: 1071382:KAFR_0A03890
uniprot id: H2AN74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0F03010
gene id: 1071382:KAFR_0F03010
uniprot id: H2AWZ7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

1071382:KAFR 0G02180
gene id: 1071382:KAFR_0G02180
uniprot id: H2AY02
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1071382:KAFR 0D00790
gene id: 1071382:KAFR_0D00790
uniprot id: H2ATM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0E02280
gene id: 1071382:KAFR_0E02280
uniprot id: H2AVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
messages: Homodimer.
messages: Preautophagosomal structure

1071382:KAFR 0A07570
gene id: 1071382:KAFR_0A07570
uniprot id: H2AP91
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071382:KAFR 0C03910
gene id: 1071382:KAFR_0C03910
uniprot id: H2ASN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

1071382:KAFR 0F03660
gene id: 1071382:KAFR_0F03660
uniprot id: H2AX62
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071382:KAFR 0A02120
gene id: 1071382:KAFR_0A02120
uniprot id: H2AMQ0
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1071382:KAFR 0A05620
gene id: 1071382:KAFR_0A05620
uniprot id: H2ANP7
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0B00970
gene id: 1071382:KAFR_0B00970
uniprot id: H2APU5
names: Similarity
messages: Belongs to the SAS10 family.

1071382:KAFR 0I00170
gene id: 1071382:KAFR_0I00170
uniprot id: H2AZJ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0I01370
gene id: 1071382:KAFR_0I01370
uniprot id: H2AZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0L00780
gene id: 1071382:KAFR_0L00780
uniprot id: H2B235
names: Similarity
messages: Belongs to the aspartokinase family.

1071382:KAFR 0B03710
gene id: 1071382:KAFR_0B03710
uniprot id: H2AQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071382:KAFR 0E02530
gene id: 1071382:KAFR_0E02530
uniprot id: H2AVK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

1071382:KAFR 0B01960
gene id: 1071382:KAFR_0B01960
uniprot id: H2AQ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0D03700
gene id: 1071382:KAFR_0D03700
uniprot id: H2AUG8
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

1071382:KAFR 0H00470
gene id: 1071382:KAFR_0H00470
uniprot id: H2AYQ0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1071382:KAFR 0B01840
gene id: 1071382:KAFR_0B01840
uniprot id: H2AQ33
names: Similarity
messages: Belongs to the PrpD family.

1071382:KAFR 0H02400
gene id: 1071382:KAFR_0H02400
uniprot id: H2AZ93
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

1071382:KAFR 0B02590
gene id: 1071382:KAFR_0B02590
uniprot id: H2AQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

1071382:KAFR 0C01160
gene id: 1071382:KAFR_0C01160
uniprot id: H2ARW1
names: Similarity
messages: Belongs to the RENT3 family.

1071382:KAFR 0F01540
gene id: 1071382:KAFR_0F01540
uniprot id: H2AWK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1071382:KAFR 0F04290
gene id: 1071382:KAFR_0F04290
uniprot id: H2AXC4
names: Similarity
messages: Belongs to the PAT1 family.

1071382:KAFR 0F03830
gene id: 1071382:KAFR_0F03830
uniprot id: H2AX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071382:KAFR 0D00210
gene id: 1071382:KAFR_0D00210
uniprot id: H2ATG7
names: Similarity
messages: Belongs to the MT-A70-like family.

1071382:KAFR 0C02290
gene id: 1071382:KAFR_0C02290
uniprot id: H2AS72
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0B04870
gene id: 1071382:KAFR_0B04870
uniprot id: H2AQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP2 family.
messages: Membrane
messages: Peroxisome membrane

1071382:KAFR 0C00760
gene id: 1071382:KAFR_0C00760
uniprot id: H2ARS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

1071382:KAFR 0A01020
gene id: 1071382:KAFR_0A01020
uniprot id: H2AME1
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1071382:KAFR 0D04880
gene id: 1071382:KAFR_0D04880
uniprot id: H2AUT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1071382:KAFR 0K00240
gene id: 1071382:KAFR_0K00240
uniprot id: H2B179
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

1071382:KAFR 0K00860
gene id: 1071382:KAFR_0K00860
uniprot id: H2B1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071382:KAFR 0A07470
gene id: 1071382:KAFR_0A07470
uniprot id: H2AP81
names: Similarity
messages: Belongs to the APC1 family.

1071382:KAFR 0D02590
gene id: 1071382:KAFR_0D02590
uniprot id: H2AU56
names: Subcellular Location Annotation
messages: Mitochondrion

1071382:KAFR 0C02870
gene id: 1071382:KAFR_0C02870
uniprot id: H2ASD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0B05280
gene id: 1071382:KAFR_0B05280
uniprot id: H2AR23
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0F00350
gene id: 1071382:KAFR_0F00350
uniprot id: H2AW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B04750
gene id: 1071382:KAFR_0B04750
uniprot id: H2AQX2
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071382:KAFR 0D00800
gene id: 1071382:KAFR_0D00800
uniprot id: H2ATM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0D02190
gene id: 1071382:KAFR_0D02190
uniprot id: H2AU16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0D02280
gene id: 1071382:KAFR_0D02280
uniprot id: H2AU25
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1071382:KAFR 0F02920
gene id: 1071382:KAFR_0F02920
uniprot id: H2AWY8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1071382:KAFR 0A03850
gene id: 1071382:KAFR_0A03850
uniprot id: H2AN70
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071382:KAFR 0I00290
gene id: 1071382:KAFR_0I00290
uniprot id: H2AZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0I02070
gene id: 1071382:KAFR_0I02070
uniprot id: H2B037
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

1071382:KAFR 0A00320
gene id: 1071382:KAFR_0A00320
uniprot id: H2AM70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AEP1 family.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.

1071382:KAFR 0A05860
gene id: 1071382:KAFR_0A05860
uniprot id: H2ANS1
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

1071382:KAFR 0E01580
gene id: 1071382:KAFR_0E01580
uniprot id: H2AVB2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071382:KAFR 0I00240
gene id: 1071382:KAFR_0I00240
uniprot id: H2AZK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

1071382:KAFR 0G01390
gene id: 1071382:KAFR_0G01390
uniprot id: H2AXS3
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

1071382:KAFR 0H02420
gene id: 1071382:KAFR_0H02420
uniprot id: H2AZ95
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0C00690
gene id: 1071382:KAFR_0C00690
uniprot id: H2B0P7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0B05110
gene id: 1071382:KAFR_0B05110
uniprot id: H2AR07
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1071382:KAFR 0G02250
gene id: 1071382:KAFR_0G02250
uniprot id: H2AY09
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D03810
gene id: 1071382:KAFR_0D03810
uniprot id: H2AUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

1071382:KAFR 0C01330
gene id: 1071382:KAFR_0C01330
uniprot id: H2ARX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

1071382:KAFR 0C01830
gene id: 1071382:KAFR_0C01830
uniprot id: H2AS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0A02280
gene id: 1071382:KAFR_0A02280
uniprot id: H2AMR6
names: Similarity
messages: Belongs to the EIS1 family.

1071382:KAFR 0E03590
gene id: 1071382:KAFR_0E03590
uniprot id: H2AVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

1071382:KAFR 0A04110
gene id: 1071382:KAFR_0A04110
uniprot id: H2AN96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0B05920
gene id: 1071382:KAFR_0B05920
uniprot id: H2AR88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

1071382:KAFR 0H01110
gene id: 1071382:KAFR_0H01110
uniprot id: H2AYW5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A00370
gene id: 1071382:KAFR_0A00370
uniprot id: H2AM75
names: Similarity
messages: Belongs to the CCDC25 family.

1071382:KAFR 0G03570
gene id: 1071382:KAFR_0G03570
uniprot id: H2AYD9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071382:KAFR 0F02480
gene id: 1071382:KAFR_0F02480
uniprot id: H2AWU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0H00480
gene id: 1071382:KAFR_0H00480
uniprot id: H2AYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

1071382:KAFR 0A06530
gene id: 1071382:KAFR_0A06530
uniprot id: H2ANY8
names: Similarity
messages: Belongs to the VPS8 family.

1071382:KAFR 0B02650
gene id: 1071382:KAFR_0B02650
uniprot id: H2AQB2
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

1071382:KAFR 0H01480
gene id: 1071382:KAFR_0H01480
uniprot id: H2AZ02
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0A00990
gene id: 1071382:KAFR_0A00990
uniprot id: H2AMD7
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0E02390
gene id: 1071382:KAFR_0E02390
uniprot id: H2AVJ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

1071382:KAFR 0L00300
gene id: 1071382:KAFR_0L00300
uniprot id: H2B1Y7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C03770
gene id: 1071382:KAFR_0C03770
uniprot id: H2ASL8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

1071382:KAFR 0G01770
gene id: 1071382:KAFR_0G01770
uniprot id: H2AXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

1071382:KAFR 0L01360
gene id: 1071382:KAFR_0L01360
uniprot id: H2B295
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

1071382:KAFR 0B00880
gene id: 1071382:KAFR_0B00880
uniprot id: H2APT6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1071382:KAFR 0E01620
gene id: 1071382:KAFR_0E01620
uniprot id: H2AVB6
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

1071382:KAFR 0J02260
gene id: 1071382:KAFR_0J02260
uniprot id: H2B0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071382:KAFR 0G03420
gene id: 1071382:KAFR_0G03420
uniprot id: H2AYC4
names: Similarity
messages: Belongs to the Mo25 family.

1071382:KAFR 0C00280
gene id: 1071382:KAFR_0C00280
uniprot id: H2ARM4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D01780
gene id: 1071382:KAFR_0D01780
uniprot id: H2ATX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B00640
gene id: 1071382:KAFR_0B00640
uniprot id: H2APR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0F01570
gene id: 1071382:KAFR_0F01570
uniprot id: H2AWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071382:KAFR 0E01140
gene id: 1071382:KAFR_0E01140
uniprot id: H2AV68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071382:KAFR 0F01950
gene id: 1071382:KAFR_0F01950
uniprot id: H2AWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0B06100
gene id: 1071382:KAFR_0B06100
uniprot id: H2ARA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

1071382:KAFR 0H03010
gene id: 1071382:KAFR_0H03010
uniprot id: H2AZF5
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

1071382:KAFR 0F03370
gene id: 1071382:KAFR_0F03370
uniprot id: H2AX33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

1071382:KAFR 0B01790
gene id: 1071382:KAFR_0B01790
uniprot id: H2AQ28
names: Similarity
messages: Belongs to the peptidase M24B family.

1071382:KAFR 0F02440
gene id: 1071382:KAFR_0F02440
uniprot id: H2AWU1
names: Similarity
messages: Belongs to the AAA ATPase family.

1071382:KAFR 0E01450
gene id: 1071382:KAFR_0E01450
uniprot id: H2AV99
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1071382:KAFR 0I00300
gene id: 1071382:KAFR_0I00300
uniprot id: H2AZL1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1071382:KAFR 0L01100
gene id: 1071382:KAFR_0L01100
uniprot id: H2B268
names: Similarity
messages: Belongs to the AIM9 family.

1071382:KAFR 0I01390
gene id: 1071382:KAFR_0I01390
uniprot id: H2AZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

1071382:KAFR 0B05370
gene id: 1071382:KAFR_0B05370
uniprot id: H2AR32
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0H03080
gene id: 1071382:KAFR_0H03080
uniprot id: H2AZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

1071382:KAFR 0E00870
gene id: 1071382:KAFR_0E00870
uniprot id: H2AZR1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1071382:KAFR 0C02020
gene id: 1071382:KAFR_0C02020
uniprot id: H2AS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0K00800
gene id: 1071382:KAFR_0K00800
uniprot id: H2B1D5
names: Similarity
messages: Belongs to the FUN14 family.

1071382:KAFR 0D04780
gene id: 1071382:KAFR_0D04780
uniprot id: H2AUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071382:KAFR 0H02890
gene id: 1071382:KAFR_0H02890
uniprot id: H2AZE2
names: Similarity
messages: Belongs to the TPP enzyme family.

1071382:KAFR 0I01590
gene id: 1071382:KAFR_0I01590
uniprot id: H2AZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

1071382:KAFR 0A08430
gene id: 1071382:KAFR_0A08430
uniprot id: H2APH7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1071382:KAFR 0A00900
gene id: 1071382:KAFR_0A00900
uniprot id: H2AMC8
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

1071382:KAFR 0D02860
gene id: 1071382:KAFR_0D02860
uniprot id: H2AU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1071382:KAFR 0G03530
gene id: 1071382:KAFR_0G03530
uniprot id: H2AYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0H03630
gene id: 1071382:KAFR_0H03630
uniprot id: H2AYJ6
names: Similarity
messages: Belongs to the AAA ATPase family.

1071382:KAFR 0A02420
gene id: 1071382:KAFR_0A02420
uniprot id: H2AMT0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0E00770
gene id: 1071382:KAFR_0E00770
uniprot id: H2AV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1071382:KAFR 0K00450
gene id: 1071382:KAFR_0K00450
uniprot id: H2B1A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071382:KAFR 0K01070
gene id: 1071382:KAFR_0K01070
uniprot id: H2B1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

1071382:KAFR 0J01250
gene id: 1071382:KAFR_0J01250
uniprot id: H2B0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

1071382:KAFR 0K01180
gene id: 1071382:KAFR_0K01180
uniprot id: H2B1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071382:KAFR 0A05670
gene id: 1071382:KAFR_0A05670
uniprot id: H2ANQ2
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

1071382:KAFR 0G01930
gene id: 1071382:KAFR_0G01930
uniprot id: H2AXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

1071382:KAFR 0I01310
gene id: 1071382:KAFR_0I01310
uniprot id: H2AZW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1071382:KAFR 0I01250
gene id: 1071382:KAFR_0I01250
uniprot id: H2AZV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0I01990
gene id: 1071382:KAFR_0I01990
uniprot id: H2B029
names: Similarity
messages: Belongs to the syntaxin family.

1071382:KAFR 0G00720
gene id: 1071382:KAFR_0G00720
uniprot id: H2AXK5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G00630
gene id: 1071382:KAFR_0G00630
uniprot id: H2AXJ6
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0K01190
gene id: 1071382:KAFR_0K01190
uniprot id: H2B1H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1071382:KAFR 0I01050
gene id: 1071382:KAFR_0I01050
uniprot id: H2AZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1071382:KAFR 0K01680
gene id: 1071382:KAFR_0K01680
uniprot id: H2B1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

1071382:KAFR 0E02490
gene id: 1071382:KAFR_0E02490
uniprot id: H2AVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0E03860
gene id: 1071382:KAFR_0E03860
uniprot id: H2AVY7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071382:KAFR 0F00730
gene id: 1071382:KAFR_0F00730
uniprot id: H2AWC0
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

1071382:KAFR 0B01120
gene id: 1071382:KAFR_0B01120
uniprot id: H2APW0
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0C04770
gene id: 1071382:KAFR_0C04770
uniprot id: H2ASW8
names: Similarity
messages: Belongs to the TRM112 family.

1071382:KAFR 0J01950
gene id: 1071382:KAFR_0J01950
uniprot id: H2B0V9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0L00250
gene id: 1071382:KAFR_0L00250
uniprot id: H2B1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

1071382:KAFR 0K01790
gene id: 1071382:KAFR_0K01790
uniprot id: H2B1N3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D01300
gene id: 1071382:KAFR_0D01300
uniprot id: H2ATS6
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

1071382:KAFR 0C03610
gene id: 1071382:KAFR_0C03610
uniprot id: H2ASK3
names: Similarity
messages: Belongs to the multicopper oxidase family.

1071382:KAFR 0K01920
gene id: 1071382:KAFR_0K01920
uniprot id: H2B1P6
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0B01530
gene id: 1071382:KAFR_0B01530
uniprot id: H2AQ02
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0E02360
gene id: 1071382:KAFR_0E02360
uniprot id: H2AVI9
names: Subcellular Location Annotation
messages: Mitochondrion

1071382:KAFR 0L00860
gene id: 1071382:KAFR_0L00860
uniprot id: H2B244
names: Similarity
messages: Belongs to the RutC family.

1071382:KAFR 0E03450
gene id: 1071382:KAFR_0E03450
uniprot id: H2AVU7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D00570
gene id: 1071382:KAFR_0D00570
uniprot id: H2ATK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

1071382:KAFR 0B04340
gene id: 1071382:KAFR_0B04340
uniprot id: H2AQT0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

1071382:KAFR 0L01950
gene id: 1071382:KAFR_0L01950
uniprot id: H2B2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

1071382:KAFR 0D02210
gene id: 1071382:KAFR_0D02210
uniprot id: H2AU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

1071382:KAFR 0L02130
gene id: 1071382:KAFR_0L02130
uniprot id: H2B2H4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0H03140
gene id: 1071382:KAFR_0H03140
uniprot id: H2AZG8
names: Similarity
messages: Belongs to the WD repeat LST8 family.

1071382:KAFR 0B01330
gene id: 1071382:KAFR_0B01330
uniprot id: H2APY2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1071382:KAFR 0A06150
gene id: 1071382:KAFR_0A06150
uniprot id: H2ANV0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0C00460
gene id: 1071382:KAFR_0C00460
uniprot id: H2ARP1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D02070
gene id: 1071382:KAFR_0D02070
uniprot id: H2AU04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1071382:KAFR 0F02180
gene id: 1071382:KAFR_0F02180
uniprot id: H2AWR5
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

1071382:KAFR 0A07960
gene id: 1071382:KAFR_0A07960
uniprot id: H2APD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

1071382:KAFR 0B03020
gene id: 1071382:KAFR_0B03020
uniprot id: H2AQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1071382:KAFR 0C03500
gene id: 1071382:KAFR_0C03500
uniprot id: H2ASJ2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0C03920
gene id: 1071382:KAFR_0C03920
uniprot id: H2ASN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0C00680
gene id: 1071382:KAFR_0C00680
uniprot id: H2ARR3
names: Similarity
messages: Belongs to the TrpF family.

1071382:KAFR 0B00720
gene id: 1071382:KAFR_0B00720
uniprot id: H2APS1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

1071382:KAFR 0J02450
gene id: 1071382:KAFR_0J02450
uniprot id: H2B109
names: Similarity
messages: Belongs to the peptidase S8 family.

1071382:KAFR 0G00750
gene id: 1071382:KAFR_0G00750
uniprot id: H2AXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071382:KAFR 0I01700
gene id: 1071382:KAFR_0I01700
uniprot id: H2B001
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0C05670
gene id: 1071382:KAFR_0C05670
uniprot id: H2AT58
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1071382:KAFR 0D02980
gene id: 1071382:KAFR_0D02980
uniprot id: H2AU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE2 family.
messages: Nucleus

1071382:KAFR 0D02160
gene id: 1071382:KAFR_0D02160
uniprot id: H2AU13
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0H00910
gene id: 1071382:KAFR_0H00910
uniprot id: H2AYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

1071382:KAFR 0F01000
gene id: 1071382:KAFR_0F01000
uniprot id: H2AWE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1071382:KAFR 0D02330
gene id: 1071382:KAFR_0D02330
uniprot id: H2AU30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

1071382:KAFR 0C06530
gene id: 1071382:KAFR_0C06530
uniprot id: H2ATE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071382:KAFR 0I02020
gene id: 1071382:KAFR_0I02020
uniprot id: H2B032
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

1071382:KAFR 0E02480
gene id: 1071382:KAFR_0E02480
uniprot id: H2AVK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

1071382:KAFR 0B01130
gene id: 1071382:KAFR_0B01130
uniprot id: H2APW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

1071382:KAFR 0C00830
gene id: 1071382:KAFR_0C00830
uniprot id: H2ARS8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A03860
gene id: 1071382:KAFR_0A03860
uniprot id: H2AN71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0F02880
gene id: 1071382:KAFR_0F02880
uniprot id: H2AWY4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C04880
gene id: 1071382:KAFR_0C04880
uniprot id: H2ASX9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0B02040
gene id: 1071382:KAFR_0B02040
uniprot id: H2AQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B03410
gene id: 1071382:KAFR_0B03410
uniprot id: H2AQI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

1071382:KAFR 0H02960
gene id: 1071382:KAFR_0H02960
uniprot id: H2AZE9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0A01100
gene id: 1071382:KAFR_0A01100
uniprot id: H2AME9
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

1071382:KAFR 0C05190
gene id: 1071382:KAFR_0C05190
uniprot id: H2AT10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

1071382:KAFR 0L01810
gene id: 1071382:KAFR_0L01810
uniprot id: H2B2E1
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

1071382:KAFR 0K00760
gene id: 1071382:KAFR_0K00760
uniprot id: H2B1D1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071382:KAFR 0B06530
gene id: 1071382:KAFR_0B06530
uniprot id: H2ARE9
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0K01030
gene id: 1071382:KAFR_0K01030
uniprot id: H2B1F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071382:KAFR 0A06770
gene id: 1071382:KAFR_0A06770
uniprot id: H2AP12
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0F03360
gene id: 1071382:KAFR_0F03360
uniprot id: H2AX32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0G02890
gene id: 1071382:KAFR_0G02890
uniprot id: H2AY71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
messages: Nucleus

1071382:KAFR 0B04230
gene id: 1071382:KAFR_0B04230
uniprot id: H2AQR9
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

1071382:KAFR 0A02030
gene id: 1071382:KAFR_0A02030
uniprot id: H2AMP1
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1071382:KAFR 0D02900
gene id: 1071382:KAFR_0D02900
uniprot id: H2AU88
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0F03930
gene id: 1071382:KAFR_0F03930
uniprot id: H2AX89
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1071382:KAFR 0G01180
gene id: 1071382:KAFR_0G01180
uniprot id: H2AXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0I00260
gene id: 1071382:KAFR_0I00260
uniprot id: H2AZK7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071382:KAFR 0I02320
gene id: 1071382:KAFR_0I02320
uniprot id: H2B061
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

1071382:KAFR 0G03560
gene id: 1071382:KAFR_0G03560
uniprot id: H2AYD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A07180
gene id: 1071382:KAFR_0A07180
uniprot id: H2AP52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071382:KAFR 0L00340
gene id: 1071382:KAFR_0L00340
uniprot id: H2B1Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

1071382:KAFR 0C00300
gene id: 1071382:KAFR_0C00300
uniprot id: H2ARM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1071382:KAFR 0D03400
gene id: 1071382:KAFR_0D03400
uniprot id: H2AUD8
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

1071382:KAFR 0B01150
gene id: 1071382:KAFR_0B01150
uniprot id: H2APW4
names: Similarity
messages: Belongs to the cullin family.

1071382:KAFR 0A08280
gene id: 1071382:KAFR_0A08280
uniprot id: H2APG2
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0B05810
gene id: 1071382:KAFR_0B05810
uniprot id: H2AR77
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0D00640
gene id: 1071382:KAFR_0D00640
uniprot id: H2ATL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0E03650
gene id: 1071382:KAFR_0E03650
uniprot id: H2AVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0C02210
gene id: 1071382:KAFR_0C02210
uniprot id: H2AS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

1071382:KAFR 0J01860
gene id: 1071382:KAFR_0J01860
uniprot id: H2B0V0
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0D00290
gene id: 1071382:KAFR_0D00290
uniprot id: H2ATH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

1071382:KAFR 0C00250
gene id: 1071382:KAFR_0C00250
uniprot id: H2ARM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1071382:KAFR 0C03340
gene id: 1071382:KAFR_0C03340
uniprot id: H2ASH6
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0A04750
gene id: 1071382:KAFR_0A04750
uniprot id: H2ANG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1071382:KAFR 0F03070
gene id: 1071382:KAFR_0F03070
uniprot id: H2AX03
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071382:KAFR 0L00390
gene id: 1071382:KAFR_0L00390
uniprot id: H2B1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0G01860
gene id: 1071382:KAFR_0G01860
uniprot id: H2AXX0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

1071382:KAFR 0H01310
gene id: 1071382:KAFR_0H01310
uniprot id: H2AYY5
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

1071382:KAFR 0J02390
gene id: 1071382:KAFR_0J02390
uniprot id: H2B103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0F03990
gene id: 1071382:KAFR_0F03990
uniprot id: H2AX94
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0J01360
gene id: 1071382:KAFR_0J01360
uniprot id: H2B0Q3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1071382:KAFR 0K01850
gene id: 1071382:KAFR_0K01850
uniprot id: H2B1N9
names: Similarity
messages: Belongs to the AAR2 family.

1071382:KAFR 0A01120
gene id: 1071382:KAFR_0A01120
uniprot id: H2AMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0L00650
gene id: 1071382:KAFR_0L00650
uniprot id: H2B222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

1071382:KAFR 0B05100
gene id: 1071382:KAFR_0B05100
uniprot id: H2AR06
names: Similarity
messages: Belongs to the SIP5 family.

1071382:KAFR 0K00470
gene id: 1071382:KAFR_0K00470
uniprot id: H2B1A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071382:KAFR 0L01000
gene id: 1071382:KAFR_0L01000
uniprot id: H2B258
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1071382:KAFR 0B02750
gene id: 1071382:KAFR_0B02750
uniprot id: H2AQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1071382:KAFR 0C02250
gene id: 1071382:KAFR_0C02250
uniprot id: H2AS68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1071382:KAFR 0A06030
gene id: 1071382:KAFR_0A06030
uniprot id: H2ANT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0C05590
gene id: 1071382:KAFR_0C05590
uniprot id: H2AT50
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071382:KAFR 0K02150
gene id: 1071382:KAFR_0K02150
uniprot id: H2B1R9
names: Similarity
messages: Belongs to the actin family.

1071382:KAFR 0G01410
gene id: 1071382:KAFR_0G01410
uniprot id: H2AXS5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1071382:KAFR 0I02560
gene id: 1071382:KAFR_0I02560
uniprot id: H2B085
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1071382:KAFR 0C04870
gene id: 1071382:KAFR_0C04870
uniprot id: H2ASX8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

1071382:KAFR 0H02140
gene id: 1071382:KAFR_0H02140
uniprot id: H2AZ67
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1071382:KAFR 0C05580
gene id: 1071382:KAFR_0C05580
uniprot id: H2AT49
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1071382:KAFR 0C04040
gene id: 1071382:KAFR_0C04040
uniprot id: H2ASP5
names: Similarity
messages: Belongs to the SEN15 family.

1071382:KAFR 0E03980
gene id: 1071382:KAFR_0E03980
uniprot id: H2AVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071382:KAFR 0C05330
gene id: 1071382:KAFR_0C05330
uniprot id: H2AT24
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071382:KAFR 0B05030
gene id: 1071382:KAFR_0B05030
uniprot id: H2AQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071382:KAFR 0H00530
gene id: 1071382:KAFR_0H00530
uniprot id: H2AYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

1071382:KAFR 0A05150
gene id: 1071382:KAFR_0A05150
uniprot id: H2ANK0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1071382:KAFR 0B01550
gene id: 1071382:KAFR_0B01550
uniprot id: H2AQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

1071382:KAFR 0I02590
gene id: 1071382:KAFR_0I02590
uniprot id: H2B088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

1071382:KAFR 0A06430
gene id: 1071382:KAFR_0A06430
uniprot id: H2ANX8
names: Subcellular Location Annotation
messages: nuclear pore complex

1071382:KAFR 0D00150
gene id: 1071382:KAFR_0D00150
uniprot id: H2ATG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

1071382:KAFR 0A01850
gene id: 1071382:KAFR_0A01850
uniprot id: H2AMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0C05410
gene id: 1071382:KAFR_0C05410
uniprot id: H2AT32
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

1071382:KAFR 0H01690
gene id: 1071382:KAFR_0H01690
uniprot id: H2AZ23
names: Similarity
messages: Belongs to the MGMT family.

1071382:KAFR 0G02340
gene id: 1071382:KAFR_0G02340
uniprot id: H2AY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071382:KAFR 0F03110
gene id: 1071382:KAFR_0F03110
uniprot id: H2AX07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

1071382:KAFR 0B05730
gene id: 1071382:KAFR_0B05730
uniprot id: H2AR69
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0L01370
gene id: 1071382:KAFR_0L01370
uniprot id: H2B296
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L00690
gene id: 1071382:KAFR_0L00690
uniprot id: H2B226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D03920
gene id: 1071382:KAFR_0D03920
uniprot id: H2AUJ0
names: Similarity
messages: Belongs to the IST1 family.

1071382:KAFR 0B05220
gene id: 1071382:KAFR_0B05220
uniprot id: H2AR18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

1071382:KAFR 0F03840
gene id: 1071382:KAFR_0F03840
uniprot id: H2AX80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0C04020
gene id: 1071382:KAFR_0C04020
uniprot id: H2ASP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1071382:KAFR 0F00470
gene id: 1071382:KAFR_0F00470
uniprot id: H2AW94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.

1071382:KAFR 0D01470
gene id: 1071382:KAFR_0D01470
uniprot id: H2ATU3
names: Similarity
messages: Belongs to the MBF1 family.

1071382:KAFR 0D02700
gene id: 1071382:KAFR_0D02700
uniprot id: H2AU68
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

1071382:KAFR 0B02910
gene id: 1071382:KAFR_0B02910
uniprot id: H2AQD8
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1071382:KAFR 0C00370
gene id: 1071382:KAFR_0C00370
uniprot id: H2ARN3
names: Similarity
messages: Belongs to the peptidase M28 family.

1071382:KAFR 0B06430
gene id: 1071382:KAFR_0B06430
uniprot id: H2ARD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0C01550
gene id: 1071382:KAFR_0C01550
uniprot id: H2ARZ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0C06220
gene id: 1071382:KAFR_0C06220
uniprot id: H2ATB4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

1071382:KAFR 0D04140
gene id: 1071382:KAFR_0D04140
uniprot id: H2AUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0A06420
gene id: 1071382:KAFR_0A06420
uniprot id: H2ANX7
names: Similarity
messages: Belongs to the CWC22 family.

1071382:KAFR 0F02020
gene id: 1071382:KAFR_0F02020
uniprot id: H2AWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

1071382:KAFR 0C03200
gene id: 1071382:KAFR_0C03200
uniprot id: H2ASG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

1071382:KAFR 0B04820
gene id: 1071382:KAFR_0B04820
uniprot id: H2AQX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0A06010
gene id: 1071382:KAFR_0A06010
uniprot id: H2ANT6
names: Similarity
messages: Belongs to the VAC14 family.

1071382:KAFR 0F03810
gene id: 1071382:KAFR_0F03810
uniprot id: H2AX77
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

1071382:KAFR 0J01100
gene id: 1071382:KAFR_0J01100
uniprot id: H2B0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

1071382:KAFR 0A05730
gene id: 1071382:KAFR_0A05730
uniprot id: H2ANQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

1071382:KAFR 0A01110
gene id: 1071382:KAFR_0A01110
uniprot id: H2AMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071382:KAFR 0H01700
gene id: 1071382:KAFR_0H01700
uniprot id: H2AZ24
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1071382:KAFR 0I02300
gene id: 1071382:KAFR_0I02300
uniprot id: H2B059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

1071382:KAFR 0G03290
gene id: 1071382:KAFR_0G03290
uniprot id: H2AYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1071382:KAFR 0D03720
gene id: 1071382:KAFR_0D03720
uniprot id: H2AUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071382:KAFR 0L01990
gene id: 1071382:KAFR_0L01990
uniprot id: H2B2G0
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

1071382:KAFR 0C02790
gene id: 1071382:KAFR_0C02790
uniprot id: H2ASC2
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

1071382:KAFR 0E00560
gene id: 1071382:KAFR_0E00560
uniprot id: H2AV10
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

1071382:KAFR 0K01410
gene id: 1071382:KAFR_0K01410
uniprot id: H2B1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

1071382:KAFR 0C01610
gene id: 1071382:KAFR_0C01610
uniprot id: H2AS04
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

1071382:KAFR 0J01900
gene id: 1071382:KAFR_0J01900
uniprot id: H2B0V4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1071382:KAFR 0C00970
gene id: 1071382:KAFR_0C00970
uniprot id: H2ARU2
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1071382:KAFR 0J01620
gene id: 1071382:KAFR_0J01620
uniprot id: H2B0S7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01220
gene id: 1071382:KAFR_0H01220
uniprot id: H2AYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1071382:KAFR 0C06010
gene id: 1071382:KAFR_0C06010
uniprot id: H2AT92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1071382:KAFR 0E01340
gene id: 1071382:KAFR_0E01340
uniprot id: H2AV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

1071382:KAFR 0B01630
gene id: 1071382:KAFR_0B01630
uniprot id: H2AQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

1071382:KAFR 0E03970
gene id: 1071382:KAFR_0E03970
uniprot id: H2AVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

1071382:KAFR 0H03230
gene id: 1071382:KAFR_0H03230
uniprot id: H2AZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

1071382:KAFR 0H03290
gene id: 1071382:KAFR_0H03290
uniprot id: H2AZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

1071382:KAFR 0B01260
gene id: 1071382:KAFR_0B01260
uniprot id: H2APX5
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

1071382:KAFR 0B04510
gene id: 1071382:KAFR_0B04510
uniprot id: H2AQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

1071382:KAFR 0G02490
gene id: 1071382:KAFR_0G02490
uniprot id: H2AY32
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K01060
gene id: 1071382:KAFR_0K01060
uniprot id: H2B1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM21 family.
messages: Involved in mitochondrial migration along actin filaments.
messages: actin patch

1071382:KAFR 0D03450
gene id: 1071382:KAFR_0D03450
uniprot id: H2AUE3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1071382:KAFR 0J01840
gene id: 1071382:KAFR_0J01840
uniprot id: H2B0U8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F02450
gene id: 1071382:KAFR_0F02450
uniprot id: H2AWU2
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0A06050
gene id: 1071382:KAFR_0A06050
uniprot id: H2ANU0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0E03660
gene id: 1071382:KAFR_0E03660
uniprot id: H2AVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

1071382:KAFR 0I01040
gene id: 1071382:KAFR_0I01040
uniprot id: H2AZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

1071382:KAFR 0G03460
gene id: 1071382:KAFR_0G03460
uniprot id: H2AYC8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F00880
gene id: 1071382:KAFR_0F00880
uniprot id: H2AWD5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0K00600
gene id: 1071382:KAFR_0K00600
uniprot id: H2B1B5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1071382:KAFR 0D04290
gene id: 1071382:KAFR_0D04290
uniprot id: H2AUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1071382:KAFR 0D01270
gene id: 1071382:KAFR_0D01270
uniprot id: H2ATS3
names: Function
names: Similarity
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.

1071382:KAFR 0C05920
gene id: 1071382:KAFR_0C05920
uniprot id: H2AT83
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C04380
gene id: 1071382:KAFR_0C04380
uniprot id: H2ASS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

1071382:KAFR 0I00150
gene id: 1071382:KAFR_0I00150
uniprot id: H2AZJ6
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1071382:KAFR 0H02770
gene id: 1071382:KAFR_0H02770
uniprot id: H2AZD0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0A07800
gene id: 1071382:KAFR_0A07800
uniprot id: H2APB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0J02640
gene id: 1071382:KAFR_0J02640
uniprot id: H2B128
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F00960
gene id: 1071382:KAFR_0F00960
uniprot id: H2AWE3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L00190
gene id: 1071382:KAFR_0L00190
uniprot id: H2B1X6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C01400
gene id: 1071382:KAFR_0C01400
uniprot id: H2ARY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1071382:KAFR 0A03700
gene id: 1071382:KAFR_0A03700
uniprot id: H2AN55
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0J00540
gene id: 1071382:KAFR_0J00540
uniprot id: H2B0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1071382:KAFR 0J02380
gene id: 1071382:KAFR_0J02380
uniprot id: H2B102
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B01050
gene id: 1071382:KAFR_0B01050
uniprot id: H2APV3
names: Similarity
messages: Belongs to the biotin--protein ligase family.

1071382:KAFR 0A07240
gene id: 1071382:KAFR_0A07240
uniprot id: H2AP58
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1071382:KAFR 0J00960
gene id: 1071382:KAFR_0J00960
uniprot id: H2B0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

1071382:KAFR 0C02720
gene id: 1071382:KAFR_0C02720
uniprot id: H2ASB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D04690
gene id: 1071382:KAFR_0D04690
uniprot id: H2AUR7
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

1071382:KAFR 0G03610
gene id: 1071382:KAFR_0G03610
uniprot id: H2AYE3
names: Similarity
messages: Belongs to the bystin family.

1071382:KAFR 0D00720
gene id: 1071382:KAFR_0D00720
uniprot id: H2ATL9
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C02320
gene id: 1071382:KAFR_0C02320
uniprot id: H2ANL8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1071382:KAFR 0A00530
gene id: 1071382:KAFR_0A00530
uniprot id: H2AM91
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1071382:KAFR 0D02470
gene id: 1071382:KAFR_0D02470
uniprot id: H2AU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

1071382:KAFR 0A04650
gene id: 1071382:KAFR_0A04650
uniprot id: H2ANF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0I01380
gene id: 1071382:KAFR_0I01380
uniprot id: H2AZW9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0D03310
gene id: 1071382:KAFR_0D03310
uniprot id: H2AUC9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A00490
gene id: 1071382:KAFR_0A00490
uniprot id: H2AM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

1071382:KAFR 0C05340
gene id: 1071382:KAFR_0C05340
uniprot id: H2AT25
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071382:KAFR 0H03750
gene id: 1071382:KAFR_0H03750
uniprot id: H2AYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

1071382:KAFR 0C00790
gene id: 1071382:KAFR_0C00790
uniprot id: H2ARS4
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1071382:KAFR 0D03390
gene id: 1071382:KAFR_0D03390
uniprot id: H2AUD7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1071382:KAFR 0F03150
gene id: 1071382:KAFR_0F03150
uniprot id: H2AX11
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A06990
gene id: 1071382:KAFR_0A06990
uniprot id: H2AP34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071382:KAFR 0E00450
gene id: 1071382:KAFR_0E00450
uniprot id: H2AUZ9
names: Similarity
messages: Belongs to the threonine aldolase family.

1071382:KAFR 0A06830
gene id: 1071382:KAFR_0A06830
uniprot id: H2AP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

1071382:KAFR 0C01570
gene id: 1071382:KAFR_0C01570
uniprot id: H2AS00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

1071382:KAFR 0H00190
gene id: 1071382:KAFR_0H00190
uniprot id: H2AYM2
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1071382:KAFR 0K00490
gene id: 1071382:KAFR_0K00490
uniprot id: H2B1A4
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0H02630
gene id: 1071382:KAFR_0H02630
uniprot id: H2AZB6
names: Similarity
messages: Belongs to the peptidase S9B family.

1071382:KAFR 0A02090
gene id: 1071382:KAFR_0A02090
uniprot id: H2AMP7
names: Similarity
messages: Belongs to the polyprenol kinase family.

1071382:KAFR 0C06350
gene id: 1071382:KAFR_0C06350
uniprot id: H2ATD1
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071382:KAFR 0C05770
gene id: 1071382:KAFR_0C05770
uniprot id: H2AT68
names: Similarity
messages: Belongs to the VPS29 family.

1071382:KAFR 0B04620
gene id: 1071382:KAFR_0B04620
uniprot id: H2AQV9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G01130
gene id: 1071382:KAFR_0G01130
uniprot id: H2AXP6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1071382:KAFR 0L00430
gene id: 1071382:KAFR_0L00430
uniprot id: H2B200
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0F04090
gene id: 1071382:KAFR_0F04090
uniprot id: H2AXA4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H03590
gene id: 1071382:KAFR_0H03590
uniprot id: H2AYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1071382:KAFR 0E02950
gene id: 1071382:KAFR_0E02950
uniprot id: H2AVP7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1071382:KAFR 0I00210
gene id: 1071382:KAFR_0I00210
uniprot id: H2AZK2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071382:KAFR 0E02380
gene id: 1071382:KAFR_0E02380
uniprot id: H2AVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

1071382:KAFR 0C05910
gene id: 1071382:KAFR_0C05910
uniprot id: H2AT82
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071382:KAFR 0E04030
gene id: 1071382:KAFR_0E04030
uniprot id: H2AW04
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1071382:KAFR 0L00600
gene id: 1071382:KAFR_0L00600
uniprot id: H2B217
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1071382:KAFR 0C03960
gene id: 1071382:KAFR_0C03960
uniprot id: H2ASN7
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071382:KAFR 0B00530
gene id: 1071382:KAFR_0B00530
uniprot id: H2APQ2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071382:KAFR 0L00900
gene id: 1071382:KAFR_0L00900
uniprot id: H2B248
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1071382:KAFR 0D01360
gene id: 1071382:KAFR_0D01360
uniprot id: H2ATT2
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

1071382:KAFR 0A06440
gene id: 1071382:KAFR_0A06440
uniprot id: H2ANX9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1071382:KAFR 0H00570
gene id: 1071382:KAFR_0H00570
uniprot id: H2AYR0
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0G03260
gene id: 1071382:KAFR_0G03260
uniprot id: H2AYA8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1071382:KAFR 0H03680
gene id: 1071382:KAFR_0H03680
uniprot id: H2AYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071382:KAFR 0F01970
gene id: 1071382:KAFR_0F01970
uniprot id: H2AWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

1071382:KAFR 0A03030
gene id: 1071382:KAFR_0A03030
uniprot id: H2AMY8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C03780
gene id: 1071382:KAFR_0C03780
uniprot id: H2ASL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0I02510
gene id: 1071382:KAFR_0I02510
uniprot id: H2B080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

1071382:KAFR 0C03370
gene id: 1071382:KAFR_0C03370
uniprot id: H2ASH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1071382:KAFR 0A07300
gene id: 1071382:KAFR_0A07300
uniprot id: H2AP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0H03700
gene id: 1071382:KAFR_0H03700
uniprot id: H2AYK3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071382:KAFR 0J00650
gene id: 1071382:KAFR_0J00650
uniprot id: H2B0I3
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1071382:KAFR 0B03970
gene id: 1071382:KAFR_0B03970
uniprot id: H2AQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

1071382:KAFR 0F02970
gene id: 1071382:KAFR_0F02970
uniprot id: H2AWZ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1071382:KAFR 0F01160
gene id: 1071382:KAFR_0F01160
uniprot id: H2AWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1071382:KAFR 0D03760
gene id: 1071382:KAFR_0D03760
uniprot id: H2AUH4
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

1071382:KAFR 0E03960
gene id: 1071382:KAFR_0E03960
uniprot id: H2AVZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071382:KAFR 0K02570
gene id: 1071382:KAFR_0K02570
uniprot id: H2B1W3
names: Similarity
messages: Belongs to the MOG1 family.

1071382:KAFR 0C02230
gene id: 1071382:KAFR_0C02230
uniprot id: H2AS66
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071382:KAFR 0B05880
gene id: 1071382:KAFR_0B05880
uniprot id: H2AR84
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071382:KAFR 0A07260
gene id: 1071382:KAFR_0A07260
uniprot id: H2AP60
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E01350
gene id: 1071382:KAFR_0E01350
uniprot id: H2AV89
names: Similarity
messages: Belongs to the ATPase delta chain family.

1071382:KAFR 0F02130
gene id: 1071382:KAFR_0F02130
uniprot id: H2AWR0
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071382:KAFR 0B00650
gene id: 1071382:KAFR_0B00650
uniprot id: H2APR4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C06080
gene id: 1071382:KAFR_0C06080
uniprot id: H2AT99
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071382:KAFR 0D02260
gene id: 1071382:KAFR_0D02260
uniprot id: H2AU23
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1071382:KAFR 0E04260
gene id: 1071382:KAFR_0E04260
uniprot id: H2AW27
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1071382:KAFR 0F03440
gene id: 1071382:KAFR_0F03440
uniprot id: H2AX40
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1071382:KAFR 0L00240
gene id: 1071382:KAFR_0L00240
uniprot id: H2B1Y1
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

1071382:KAFR 0K01240
gene id: 1071382:KAFR_0K01240
uniprot id: H2B1H9
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071382:KAFR 0B00380
gene id: 1071382:KAFR_0B00380
uniprot id: H2APN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

1071382:KAFR 0G01740
gene id: 1071382:KAFR_0G01740
uniprot id: H2AXV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0C02500
gene id: 1071382:KAFR_0C02500
uniprot id: H2AS93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

1071382:KAFR 0C04730
gene id: 1071382:KAFR_0C04730
uniprot id: H2ASW4
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1071382:KAFR 0G02690
gene id: 1071382:KAFR_0G02690
uniprot id: H2AY50
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

1071382:KAFR 0F01510
gene id: 1071382:KAFR_0F01510
uniprot id: H2AWJ8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C04830
gene id: 1071382:KAFR_0C04830
uniprot id: H2ASX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

1071382:KAFR 0A08100
gene id: 1071382:KAFR_0A08100
uniprot id: H2APE4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

1071382:KAFR 0D03030
gene id: 1071382:KAFR_0D03030
uniprot id: H2AUA1
names: Similarity
messages: Belongs to the RRN3 family.

1071382:KAFR 0L00760
gene id: 1071382:KAFR_0L00760
uniprot id: H2B233
names: Similarity
messages: Belongs to the TPA1 family.

1071382:KAFR 0K01780
gene id: 1071382:KAFR_0K01780
uniprot id: H2B1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

1071382:KAFR 0D01770
gene id: 1071382:KAFR_0D01770
uniprot id: H2ATX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1071382:KAFR 0I01690
gene id: 1071382:KAFR_0I01690
uniprot id: H2B000
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1071382:KAFR 0G00560
gene id: 1071382:KAFR_0G00560
uniprot id: H2AXI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B05630
gene id: 1071382:KAFR_0B05630
uniprot id: H2AR59
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01590
gene id: 1071382:KAFR_0H01590
uniprot id: H2AZ13
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1071382:KAFR 0J01400
gene id: 1071382:KAFR_0J01400
uniprot id: H2B0Q7
names: Similarity
messages: Belongs to the FYV10 family.

1071382:KAFR 0A05910
gene id: 1071382:KAFR_0A05910
uniprot id: H2ANS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0G00410
gene id: 1071382:KAFR_0G00410
uniprot id: H2AXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

1071382:KAFR 0I02540
gene id: 1071382:KAFR_0I02540
uniprot id: H2B083
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A06740
gene id: 1071382:KAFR_0A06740
uniprot id: H2AP09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

1071382:KAFR 0A01440
gene id: 1071382:KAFR_0A01440
uniprot id: H2AMI2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E00230
gene id: 1071382:KAFR_0E00230
uniprot id: H2AUX7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D02560
gene id: 1071382:KAFR_0D02560
uniprot id: H2AU53
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A07920
gene id: 1071382:KAFR_0A07920
uniprot id: H2APC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

1071382:KAFR 0D04890
gene id: 1071382:KAFR_0D04890
uniprot id: H2AUT6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0B00460
gene id: 1071382:KAFR_0B00460
uniprot id: H2APP6
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

1071382:KAFR 0E02320
gene id: 1071382:KAFR_0E02320
uniprot id: H2AVI5
names: Similarity
messages: Belongs to the FMO family.

1071382:KAFR 0H01060
gene id: 1071382:KAFR_0H01060
uniprot id: H2AYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

1071382:KAFR 0C03620
gene id: 1071382:KAFR_0C03620
uniprot id: H2ASK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071382:KAFR 0H03530
gene id: 1071382:KAFR_0H03530
uniprot id: H2AYI6
names: Similarity
messages: Belongs to the LTV1 family.

1071382:KAFR 0A03650
gene id: 1071382:KAFR_0A03650
uniprot id: H2AN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

1071382:KAFR 0A03470
gene id: 1071382:KAFR_0A03470
uniprot id: H2AN32
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071382:KAFR 0K00170
gene id: 1071382:KAFR_0K00170
uniprot id: H2B172
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1071382:KAFR 0J00160
gene id: 1071382:KAFR_0J00160
uniprot id: H2B0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1071382:KAFR 0E02510
gene id: 1071382:KAFR_0E02510
uniprot id: H2AVK4
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

1071382:KAFR 0F02960
gene id: 1071382:KAFR_0F02960
uniprot id: H2AWZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1071382:KAFR 0J00370
gene id: 1071382:KAFR_0J00370
uniprot id: H2B0F5
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

1071382:KAFR 0A07510
gene id: 1071382:KAFR_0A07510
uniprot id: H2AP85
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1071382:KAFR 0H03570
gene id: 1071382:KAFR_0H03570
uniprot id: H2AYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0B00320
gene id: 1071382:KAFR_0B00320
uniprot id: H2APN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

1071382:KAFR 0B06390
gene id: 1071382:KAFR_0B06390
uniprot id: H2ARD5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1071382:KAFR 0C00210
gene id: 1071382:KAFR_0C00210
uniprot id: H2ARL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

1071382:KAFR 0I01650
gene id: 1071382:KAFR_0I01650
uniprot id: H2AZZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0K00200
gene id: 1071382:KAFR_0K00200
uniprot id: H2B175
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0C04180
gene id: 1071382:KAFR_0C04180
uniprot id: H2ASQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Required for assembly of cytochrome c oxidase (complex IV).

1071382:KAFR 0C06330
gene id: 1071382:KAFR_0C06330
uniprot id: H2ATC9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1071382:KAFR 0D03250
gene id: 1071382:KAFR_0D03250
uniprot id: H2AUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

1071382:KAFR 0L01050
gene id: 1071382:KAFR_0L01050
uniprot id: H2APY2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1071382:KAFR 0A02210
gene id: 1071382:KAFR_0A02210
uniprot id: H2AMQ9
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071382:KAFR 0E03480
gene id: 1071382:KAFR_0E03480
uniprot id: H2AVU9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D00420
gene id: 1071382:KAFR_0D00420
uniprot id: H2ATI9
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

1071382:KAFR 0E02520
gene id: 1071382:KAFR_0E02520
uniprot id: H2AVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1071382:KAFR 0G02800
gene id: 1071382:KAFR_0G02800
uniprot id: H2AY61
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071382:KAFR 0C06380
gene id: 1071382:KAFR_0C06380
uniprot id: H2ATD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

1071382:KAFR 0B05240
gene id: 1071382:KAFR_0B05240
uniprot id: H2AR20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

1071382:KAFR 0C00780
gene id: 1071382:KAFR_0C00780
uniprot id: H2AWU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0C01240
gene id: 1071382:KAFR_0C01240
uniprot id: H2ARW9
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

1071382:KAFR 0B04690
gene id: 1071382:KAFR_0B04690
uniprot id: H2AQW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

1071382:KAFR 0A04900
gene id: 1071382:KAFR_0A04900
uniprot id: H2ANH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

1071382:KAFR 0D05170
gene id: 1071382:KAFR_0D05170
uniprot id: H2AUW2
names: Similarity
messages: Belongs to the GST superfamily.

1071382:KAFR 0A05830
gene id: 1071382:KAFR_0A05830
uniprot id: H2ANR8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

1071382:KAFR 0D02930
gene id: 1071382:KAFR_0D02930
uniprot id: H2AU91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1071382:KAFR 0B01110
gene id: 1071382:KAFR_0B01110
uniprot id: H2APV9
names: Similarity
messages: Belongs to the Rho GDI family.

1071382:KAFR 0A07150
gene id: 1071382:KAFR_0A07150
uniprot id: H2AP49
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1071382:KAFR 0B00310
gene id: 1071382:KAFR_0B00310
uniprot id: H2APN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

1071382:KAFR 0B00390
gene id: 1071382:KAFR_0B00390
uniprot id: H2APN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

1071382:KAFR 0C00450
gene id: 1071382:KAFR_0C00450
uniprot id: H2ARP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

1071382:KAFR 0D01550
gene id: 1071382:KAFR_0D01550
uniprot id: H2ATV1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F03190
gene id: 1071382:KAFR_0F03190
uniprot id: H2AX15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1071382:KAFR 0E01290
gene id: 1071382:KAFR_0E01290
uniprot id: H2AV83
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0B03770
gene id: 1071382:KAFR_0B03770
uniprot id: H2AQM3
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1071382:KAFR 0A01370
gene id: 1071382:KAFR_0A01370
uniprot id: H2AMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

1071382:KAFR 0I01750
gene id: 1071382:KAFR_0I01750
uniprot id: H2B006
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

1071382:KAFR 0C05000
gene id: 1071382:KAFR_0C05000
uniprot id: H2ASZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0B01870
gene id: 1071382:KAFR_0B01870
uniprot id: H2AQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAT1 family.
messages: Cytoplasm

1071382:KAFR 0E02400
gene id: 1071382:KAFR_0E02400
uniprot id: H2AVJ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

1071382:KAFR 0B00610
gene id: 1071382:KAFR_0B00610
uniprot id: H2APR0
names: Similarity
messages: Belongs to the PPP4R2 family.

1071382:KAFR 0B02330
gene id: 1071382:KAFR_0B02330
uniprot id: H2AQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

1071382:KAFR 0A03760
gene id: 1071382:KAFR_0A03760
uniprot id: H2AN61
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1071382:KAFR 0H02020
gene id: 1071382:KAFR_0H02020
uniprot id: H2AZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B02680
gene id: 1071382:KAFR_0B02680
uniprot id: H2AQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1071382:KAFR 0E00810
gene id: 1071382:KAFR_0E00810
uniprot id: H2AV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

1071382:KAFR 0A08700
gene id: 1071382:KAFR_0A08700
uniprot id: H2APK4
names: Similarity
messages: Belongs to the DCP1 family.

1071382:KAFR 0A02920
gene id: 1071382:KAFR_0A02920
uniprot id: H2AMX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071382:KAFR 0B01940
gene id: 1071382:KAFR_0B01940
uniprot id: H2AQ42
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A01450
gene id: 1071382:KAFR_0A01450
uniprot id: H2AMI3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1071382:KAFR 0B05010
gene id: 1071382:KAFR_0B05010
uniprot id: H2AQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSW5 family.
messages: Involved in spore wall assembly.
messages: Membrane

1071382:KAFR 0B04500
gene id: 1071382:KAFR_0B04500
uniprot id: H2AQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0E03270
gene id: 1071382:KAFR_0E03270
uniprot id: H2AVS9
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

1071382:KAFR 0E03810
gene id: 1071382:KAFR_0E03810
uniprot id: H2AVY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1071382:KAFR 0J02270
gene id: 1071382:KAFR_0J02270
uniprot id: H2B0Z1
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071382:KAFR 0A01260
gene id: 1071382:KAFR_0A01260
uniprot id: H2AMG5
names: Similarity
messages: Belongs to the PPase family.

1071382:KAFR 0F02300
gene id: 1071382:KAFR_0F02300
uniprot id: H2AWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0B02460
gene id: 1071382:KAFR_0B02460
uniprot id: H2AQ94
names: Similarity
messages: Belongs to the SPT2 family.

1071382:KAFR 0C05990
gene id: 1071382:KAFR_0C05990
uniprot id: H2AT90
names: Similarity
messages: Belongs to the syntaxin family.

1071382:KAFR 0B03180
gene id: 1071382:KAFR_0B03180
uniprot id: H2AQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

1071382:KAFR 0G03160
gene id: 1071382:KAFR_0G03160
uniprot id: H2AY98
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

1071382:KAFR 0E01410
gene id: 1071382:KAFR_0E01410
uniprot id: H2AV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0K02510
gene id: 1071382:KAFR_0K02510
uniprot id: H2B1V7
names: Similarity
messages: Belongs to the dpy-30 family.

1071382:KAFR 0J02410
gene id: 1071382:KAFR_0J02410
uniprot id: H2B105
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

1071382:KAFR 0B05090
gene id: 1071382:KAFR_0B05090
uniprot id: H2AR05
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071382:KAFR 0H02850
gene id: 1071382:KAFR_0H02850
uniprot id: H2AZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1071382:KAFR 0H00840
gene id: 1071382:KAFR_0H00840
uniprot id: H2AYT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1071382:KAFR 0G03350
gene id: 1071382:KAFR_0G03350
uniprot id: H2AYB7
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071382:KAFR 0F04400
gene id: 1071382:KAFR_0F04400
uniprot id: H2AXD5
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1071382:KAFR 0A04360
gene id: 1071382:KAFR_0A04360
uniprot id: H2ANC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

1071382:KAFR 0H02490
gene id: 1071382:KAFR_0H02490
uniprot id: H2AZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

1071382:KAFR 0A04370
gene id: 1071382:KAFR_0A04370
uniprot id: H2ANC2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0G00160
gene id: 1071382:KAFR_0G00160
uniprot id: H2AXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0I00570
gene id: 1071382:KAFR_0I00570
uniprot id: H2AZN8
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

1071382:KAFR 0C01040
gene id: 1071382:KAFR_0C01040
uniprot id: H2ARU9
names: Similarity
messages: Belongs to the actin family.

1071382:KAFR 0E00800
gene id: 1071382:KAFR_0E00800
uniprot id: H2AV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

1071382:KAFR 0G02600
gene id: 1071382:KAFR_0G02600
uniprot id: H2ANK0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1071382:KAFR 0I02090
gene id: 1071382:KAFR_0I02090
uniprot id: H2B039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071382:KAFR 0G00230
gene id: 1071382:KAFR_0G00230
uniprot id: H2AXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071382:KAFR 0G01470
gene id: 1071382:KAFR_0G01470
uniprot id: H2AXT1
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

1071382:KAFR 0A01070
gene id: 1071382:KAFR_0A01070
uniprot id: H2AME6
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1071382:KAFR 0B06680
gene id: 1071382:KAFR_0B06680
uniprot id: H2ARG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1071382:KAFR 0B02490
gene id: 1071382:KAFR_0B02490
uniprot id: H2AQ97
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C03530
gene id: 1071382:KAFR_0C03530
uniprot id: H2ASJ5
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

1071382:KAFR 0J02780
gene id: 1071382:KAFR_0J02780
uniprot id: H2B142
names: Similarity
messages: Belongs to the SAPS family.

1071382:KAFR 0E00260
gene id: 1071382:KAFR_0E00260
uniprot id: H2AUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

1071382:KAFR 0D02770
gene id: 1071382:KAFR_0D02770
uniprot id: H2AU75
names: Similarity
messages: Belongs to the SUN family.

1071382:KAFR 0E03780
gene id: 1071382:KAFR_0E03780
uniprot id: H2AVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

1071382:KAFR 0E02200
gene id: 1071382:KAFR_0E02200
uniprot id: H2AVH3
names: Similarity
messages: Belongs to the TFIIB family.

1071382:KAFR 0J01580
gene id: 1071382:KAFR_0J01580
uniprot id: H2B0S3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0B01580
gene id: 1071382:KAFR_0B01580
uniprot id: H2AQ07
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

1071382:KAFR 0F03060
gene id: 1071382:KAFR_0F03060
uniprot id: H2AX02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1071382:KAFR 0J01040
gene id: 1071382:KAFR_0J01040
uniprot id: H2B0M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

1071382:KAFR 0A04100
gene id: 1071382:KAFR_0A04100
uniprot id: H2AN95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

1071382:KAFR 0H02050
gene id: 1071382:KAFR_0H02050
uniprot id: H2AZ58
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E03200
gene id: 1071382:KAFR_0E03200
uniprot id: H2AVS2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01510
gene id: 1071382:KAFR_0A01510
uniprot id: H2AMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

1071382:KAFR 0D02080
gene id: 1071382:KAFR_0D02080
uniprot id: H2AU05
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

1071382:KAFR 0E00530
gene id: 1071382:KAFR_0E00530
uniprot id: H2AV07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

1071382:KAFR 0I00990
gene id: 1071382:KAFR_0I00990
uniprot id: H2AZT0
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

1071382:KAFR 0B02280
gene id: 1071382:KAFR_0B02280
uniprot id: H2AQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

1071382:KAFR 0C05420
gene id: 1071382:KAFR_0C05420
uniprot id: H2AT33
names: Similarity
messages: Belongs to the sorting nexin family.

1071382:KAFR 0E00300
gene id: 1071382:KAFR_0E00300
uniprot id: H2AUY4
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071382:KAFR 0A03620
gene id: 1071382:KAFR_0A03620
uniprot id: H2AN47
names: Similarity
messages: Belongs to the peptidase M28 family.

1071382:KAFR 0H02350
gene id: 1071382:KAFR_0H02350
uniprot id: H2AZ88
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071382:KAFR 0A01820
gene id: 1071382:KAFR_0A01820
uniprot id: H2AMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F00930
gene id: 1071382:KAFR_0F00930
uniprot id: H2AWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: Membrane

1071382:KAFR 0L01390
gene id: 1071382:KAFR_0L01390
uniprot id: H2B298
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

1071382:KAFR 0E03230
gene id: 1071382:KAFR_0E03230
uniprot id: H2AVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B05760
gene id: 1071382:KAFR_0B05760
uniprot id: H2AR72
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1071382:KAFR 0J01990
gene id: 1071382:KAFR_0J01990
uniprot id: H2B0W3
names: Similarity
messages: Belongs to the syntaxin family.

1071382:KAFR 0A06470
gene id: 1071382:KAFR_0A06470
uniprot id: H2ANY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

1071382:KAFR 0A05550
gene id: 1071382:KAFR_0A05550
uniprot id: H2ANP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0F00850
gene id: 1071382:KAFR_0F00850
uniprot id: H2AWD2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J01190
gene id: 1071382:KAFR_0J01190
uniprot id: H2B0N6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1071382:KAFR 0J00930
gene id: 1071382:KAFR_0J00930
uniprot id: H2B0L1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J00270
gene id: 1071382:KAFR_0J00270
uniprot id: H2B0E5
names: Similarity
messages: Belongs to the SAPS family.

1071382:KAFR 0E04300
gene id: 1071382:KAFR_0E04300
uniprot id: H2AW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0B01010
gene id: 1071382:KAFR_0B01010
uniprot id: H2APU9
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

1071382:KAFR 0B06920
gene id: 1071382:KAFR_0B06920
uniprot id: H2ARI9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1071382:KAFR 0L00320
gene id: 1071382:KAFR_0L00320
uniprot id: H2B1Y9
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A05870
gene id: 1071382:KAFR_0A05870
uniprot id: H2ANS2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A03680
gene id: 1071382:KAFR_0A03680
uniprot id: H2AN53
names: Similarity
messages: Belongs to the PAF1 family.

1071382:KAFR 0A05770
gene id: 1071382:KAFR_0A05770
uniprot id: H2ANR2
names: Similarity
messages: Belongs to the CDC73 family.

1071382:KAFR 0A02900
gene id: 1071382:KAFR_0A02900
uniprot id: H2AMX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1071382:KAFR 0C02880
gene id: 1071382:KAFR_0C02880
uniprot id: H2ASD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

1071382:KAFR 0A06280
gene id: 1071382:KAFR_0A06280
uniprot id: H2ANW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

1071382:KAFR 0E00270
gene id: 1071382:KAFR_0E00270
uniprot id: H2AUY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0E01800
gene id: 1071382:KAFR_0E01800
uniprot id: H2AVD4
names: Similarity
messages: Belongs to the peptidase S9B family.

1071382:KAFR 0F03720
gene id: 1071382:KAFR_0F03720
uniprot id: H2AX68
names: Similarity
messages: Belongs to the TACO1 family.

1071382:KAFR 0B01410
gene id: 1071382:KAFR_0B01410
uniprot id: H2APZ0
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1071382:KAFR 0I00800
gene id: 1071382:KAFR_0I00800
uniprot id: H2AZR1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1071382:KAFR 0E00180
gene id: 1071382:KAFR_0E00180
uniprot id: H2AUX2
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0D02520
gene id: 1071382:KAFR_0D02520
uniprot id: H2AU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG14 family.
messages: Vacuole membrane

1071382:KAFR 0G01840
gene id: 1071382:KAFR_0G01840
uniprot id: H2AXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0E00655
gene id: 1071382:KAFR_0E00655
uniprot id: H2AV20
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1071382:KAFR 0D00890
gene id: 1071382:KAFR_0D00890
uniprot id: H2ATN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0H00540
gene id: 1071382:KAFR_0H00540
uniprot id: H2AYQ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0A06090
gene id: 1071382:KAFR_0A06090
uniprot id: H2ANU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

1071382:KAFR 0H02460
gene id: 1071382:KAFR_0H02460
uniprot id: H2AZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0A08330
gene id: 1071382:KAFR_0A08330
uniprot id: H2APG7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A08420
gene id: 1071382:KAFR_0A08420
uniprot id: H2APH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1071382:KAFR 0D00550
gene id: 1071382:KAFR_0D00550
uniprot id: H2ATK2
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

1071382:KAFR 0E00170
gene id: 1071382:KAFR_0E00170
uniprot id: H2AUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YRA1 family.
messages: Involved in export of poly(A) mRNAs from the nucleus. Recruited to the coding sequences as well as poly-A sites of active genes.
messages: Nucleus

1071382:KAFR 0C03440
gene id: 1071382:KAFR_0C03440
uniprot id: H2ASI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

1071382:KAFR 0H03260
gene id: 1071382:KAFR_0H03260
uniprot id: H2AZI0
names: Similarity
messages: Belongs to the PPC synthetase family.

1071382:KAFR 0B00300
gene id: 1071382:KAFR_0B00300
uniprot id: H2APN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

1071382:KAFR 0L00530
gene id: 1071382:KAFR_0L00530
uniprot id: H2B210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: actin patch

1071382:KAFR 0G01050
gene id: 1071382:KAFR_0G01050
uniprot id: H2AXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

1071382:KAFR 0B04180
gene id: 1071382:KAFR_0B04180
uniprot id: H2AQR4
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1071382:KAFR 0C04660
gene id: 1071382:KAFR_0C04660
uniprot id: H2ASV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1071382:KAFR 0L02040
gene id: 1071382:KAFR_0L02040
uniprot id: H2B2G5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071382:KAFR 0C04150
gene id: 1071382:KAFR_0C04150
uniprot id: H2ASQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

1071382:KAFR 0I02810
gene id: 1071382:KAFR_0I02810
uniprot id: H2B0B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

1071382:KAFR 0H03270
gene id: 1071382:KAFR_0H03270
uniprot id: H2AZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

1071382:KAFR 0H00930
gene id: 1071382:KAFR_0H00930
uniprot id: H2AYU7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

1071382:KAFR 0C02940
gene id: 1071382:KAFR_0C02940
uniprot id: H2ASD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F02290
gene id: 1071382:KAFR_0F02290
uniprot id: H2AWS6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1071382:KAFR 0G03210
gene id: 1071382:KAFR_0G03210
uniprot id: H2AYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD52 family.
messages: Interacts with RAD51 and RAD52.
messages: Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA.
messages: Nucleus

1071382:KAFR 0C03510
gene id: 1071382:KAFR_0C03510
uniprot id: H2ASJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

1071382:KAFR 0D03140
gene id: 1071382:KAFR_0D03140
uniprot id: H2AUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

1071382:KAFR 0K00840
gene id: 1071382:KAFR_0K00840
uniprot id: H2B1D9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D01600
gene id: 1071382:KAFR_0D01600
uniprot id: H2ATV6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

1071382:KAFR 0D03080
gene id: 1071382:KAFR_0D03080
uniprot id: H2AUA6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E03100
gene id: 1071382:KAFR_0E03100
uniprot id: H2AVR2
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0H00590
gene id: 1071382:KAFR_0H00590
uniprot id: H2AYR2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1071382:KAFR 0G02750
gene id: 1071382:KAFR_0G02750
uniprot id: H2AY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0C05610
gene id: 1071382:KAFR_0C05610
uniprot id: H2AT52
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

1071382:KAFR 0E00820
gene id: 1071382:KAFR_0E00820
uniprot id: H2AV36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

1071382:KAFR 0E03210
gene id: 1071382:KAFR_0E03210
uniprot id: H2AVS3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

1071382:KAFR 0C02570
gene id: 1071382:KAFR_0C02570
uniprot id: H2ASA0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1071382:KAFR 0D00710
gene id: 1071382:KAFR_0D00710
uniprot id: H2ATL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

1071382:KAFR 0E01650
gene id: 1071382:KAFR_0E01650
uniprot id: H2AVB9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

1071382:KAFR 0A03740
gene id: 1071382:KAFR_0A03740
uniprot id: H2AN59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1071382:KAFR 0E00580
gene id: 1071382:KAFR_0E00580
uniprot id: H2AWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071382:KAFR 0E01930
gene id: 1071382:KAFR_0E01930
uniprot id: H2AVE7
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

1071382:KAFR 0B00870
gene id: 1071382:KAFR_0B00870
uniprot id: H2APT5
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0I00180
gene id: 1071382:KAFR_0I00180
uniprot id: H2AZJ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0L02030
gene id: 1071382:KAFR_0L02030
uniprot id: H2B2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

1071382:KAFR 0B02270
gene id: 1071382:KAFR_0B02270
uniprot id: H2AQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

1071382:KAFR 0F01460
gene id: 1071382:KAFR_0F01460
uniprot id: H2AWJ2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A08630
gene id: 1071382:KAFR_0A08630
uniprot id: H2APJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1071382:KAFR 0B05290
gene id: 1071382:KAFR_0B05290
uniprot id: H2AR24
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0I02330
gene id: 1071382:KAFR_0I02330
uniprot id: H2B062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0E01000
gene id: 1071382:KAFR_0E01000
uniprot id: H2AV54
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

1071382:KAFR 0I00650
gene id: 1071382:KAFR_0I00650
uniprot id: H2AZP6
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

1071382:KAFR 0B02250
gene id: 1071382:KAFR_0B02250
uniprot id: H2AQ73
names: Similarity
messages: Belongs to the oligoribonuclease family.

1071382:KAFR 0A00540
gene id: 1071382:KAFR_0A00540
uniprot id: H2AM92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0D02030
gene id: 1071382:KAFR_0D02030
uniprot id: H2AU00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071382:KAFR 0G01700
gene id: 1071382:KAFR_0G01700
uniprot id: H2AXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

1071382:KAFR 0B06870
gene id: 1071382:KAFR_0B06870
uniprot id: H2ARI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D04490
gene id: 1071382:KAFR_0D04490
uniprot id: H2AUP7
names: Similarity
messages: Belongs to the thymidylate kinase family.

1071382:KAFR 0G02300
gene id: 1071382:KAFR_0G02300
uniprot id: H2AY14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

1071382:KAFR 0E02370
gene id: 1071382:KAFR_0E02370
uniprot id: H2AVJ0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1071382:KAFR 0E03570
gene id: 1071382:KAFR_0E03570
uniprot id: H2AVV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0A03710
gene id: 1071382:KAFR_0A03710
uniprot id: H2AN56
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0D03990
gene id: 1071382:KAFR_0D03990
uniprot id: H2AUJ7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B07030
gene id: 1071382:KAFR_0B07030
uniprot id: H2ARK1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0J00400
gene id: 1071382:KAFR_0J00400
uniprot id: H2B0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0I01870
gene id: 1071382:KAFR_0I01870
uniprot id: H2B017
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

1071382:KAFR 0A07410
gene id: 1071382:KAFR_0A07410
uniprot id: H2AP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IBD2 family.
messages: spindle pole

1071382:KAFR 0H02800
gene id: 1071382:KAFR_0H02800
uniprot id: H2AZD3
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1071382:KAFR 0J01090
gene id: 1071382:KAFR_0J01090
uniprot id: H2B0M6
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

1071382:KAFR 0D04300
gene id: 1071382:KAFR_0D04300
uniprot id: H2AUM8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1071382:KAFR 0I01140
gene id: 1071382:KAFR_0I01140
uniprot id: H2AZU5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

1071382:KAFR 0A03340
gene id: 1071382:KAFR_0A03340
uniprot id: H2AN19
names: Similarity
messages: Belongs to the SUN family.

1071382:KAFR 0A04500
gene id: 1071382:KAFR_0A04500
uniprot id: H2AND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

1071382:KAFR 0H01890
gene id: 1071382:KAFR_0H01890
uniprot id: H2AZ42
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071382:KAFR 0C01300
gene id: 1071382:KAFR_0C01300
uniprot id: H2ARX3
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

1071382:KAFR 0F03140
gene id: 1071382:KAFR_0F03140
uniprot id: H2AX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071382:KAFR 0I02220
gene id: 1071382:KAFR_0I02220
uniprot id: H2B051
names: Similarity
messages: Belongs to the DCC1 family.

1071382:KAFR 0C01520
gene id: 1071382:KAFR_0C01520
uniprot id: H2ARZ5
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0D04260
gene id: 1071382:KAFR_0D04260
uniprot id: H2AUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

1071382:KAFR 0G00910
gene id: 1071382:KAFR_0G00910
uniprot id: H2AXM4
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

1071382:KAFR 0H00450
gene id: 1071382:KAFR_0H00450
uniprot id: H2AYP8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

1071382:KAFR 0G00220
gene id: 1071382:KAFR_0G00220
uniprot id: H2AXF5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1071382:KAFR 0E02080
gene id: 1071382:KAFR_0E02080
uniprot id: H2AVG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071382:KAFR 0K01750
gene id: 1071382:KAFR_0K01750
uniprot id: H2B1M9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1071382:KAFR 0C01480
gene id: 1071382:KAFR_0C01480
uniprot id: H2ARZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0K00210
gene id: 1071382:KAFR_0K00210
uniprot id: H2B176
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A04420
gene id: 1071382:KAFR_0A04420
uniprot id: H2ANC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

1071382:KAFR 0B04380
gene id: 1071382:KAFR_0B04380
uniprot id: H2AQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

1071382:KAFR 0C05650
gene id: 1071382:KAFR_0C05650
uniprot id: H2AT56
names: Similarity
messages: Belongs to the RAD52 family.

1071382:KAFR 0L01680
gene id: 1071382:KAFR_0L01680
uniprot id: H2B2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1071382:KAFR 0J01430
gene id: 1071382:KAFR_0J01430
uniprot id: H2B0R0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1071382:KAFR 0D02630
gene id: 1071382:KAFR_0D02630
uniprot id: H2AU61
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

1071382:KAFR 0C03940
gene id: 1071382:KAFR_0C03940
uniprot id: H2ASN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B01900
gene id: 1071382:KAFR_0B01900
uniprot id: H2AQ39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1071382:KAFR 0D00990
gene id: 1071382:KAFR_0D00990
uniprot id: H2ATP6
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071382:KAFR 0B02450
gene id: 1071382:KAFR_0B02450
uniprot id: H2AQ93
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B02850
gene id: 1071382:KAFR_0B02850
uniprot id: H2AQD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the dehydroquinate synthase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

1071382:KAFR 0G01910
gene id: 1071382:KAFR_0G01910
uniprot id: H2AXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

1071382:KAFR 0D03550
gene id: 1071382:KAFR_0D03550
uniprot id: H2AUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

1071382:KAFR 0F00860
gene id: 1071382:KAFR_0F00860
uniprot id: H2AWD3
names: Similarity
messages: Belongs to the uridine kinase family.

1071382:KAFR 0D02540
gene id: 1071382:KAFR_0D02540
uniprot id: H2AU51
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1071382:KAFR 0H01830
gene id: 1071382:KAFR_0H01830
uniprot id: H2AZ37
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

1071382:KAFR 0C04320
gene id: 1071382:KAFR_0C04320
uniprot id: H2ASS2
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071382:KAFR 0B01750
gene id: 1071382:KAFR_0B01750
uniprot id: H2AQ24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1071382:KAFR 0E02810
gene id: 1071382:KAFR_0E02810
uniprot id: H2AVN3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0B02370
gene id: 1071382:KAFR_0B02370
uniprot id: H2AQ85
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0B03920
gene id: 1071382:KAFR_0B03920
uniprot id: H2AQN8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1071382:KAFR 0A03640
gene id: 1071382:KAFR_0A03640
uniprot id: H2AN49
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

1071382:KAFR 0D04280
gene id: 1071382:KAFR_0D04280
uniprot id: H2AUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

1071382:KAFR 0C05010
gene id: 1071382:KAFR_0C05010
uniprot id: H2ASZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1071382:KAFR 0D00830
gene id: 1071382:KAFR_0D00830
uniprot id: H2ATN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

1071382:KAFR 0G00930
gene id: 1071382:KAFR_0G00930
uniprot id: H2AXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F00160
gene id: 1071382:KAFR_0F00160
uniprot id: H2AW63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

1071382:KAFR 0D02710
gene id: 1071382:KAFR_0D02710
uniprot id: H2AU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

1071382:KAFR 0J02080
gene id: 1071382:KAFR_0J02080
uniprot id: H2B0X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071382:KAFR 0J00640
gene id: 1071382:KAFR_0J00640
uniprot id: H2B0I2
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1071382:KAFR 0C02010
gene id: 1071382:KAFR_0C02010
uniprot id: H2AS44
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071382:KAFR 0A01890
gene id: 1071382:KAFR_0A01890
uniprot id: H2AMM7
names: Similarity
messages: Belongs to the cytochrome b5 family.

1071382:KAFR 0H01930
gene id: 1071382:KAFR_0H01930
uniprot id: H2AZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1071382:KAFR 0B04130
gene id: 1071382:KAFR_0B04130
uniprot id: H2AQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

1071382:KAFR 0B05700
gene id: 1071382:KAFR_0B05700
uniprot id: H2AR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

1071382:KAFR 0D04420
gene id: 1071382:KAFR_0D04420
uniprot id: H2AUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

1071382:KAFR 0C04840
gene id: 1071382:KAFR_0C04840
uniprot id: H2ASX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

1071382:KAFR 0C03320
gene id: 1071382:KAFR_0C03320
uniprot id: H2ASH4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071382:KAFR 0F00900
gene id: 1071382:KAFR_0F00900
uniprot id: H2AWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0L00480
gene id: 1071382:KAFR_0L00480
uniprot id: H2B205
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

1071382:KAFR 0E01860
gene id: 1071382:KAFR_0E01860
uniprot id: H2AVE0
names: Similarity
messages: Belongs to the MEMO1 family.

1071382:KAFR 0H02930
gene id: 1071382:KAFR_0H02930
uniprot id: H2AZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

1071382:KAFR 0A02650
gene id: 1071382:KAFR_0A02650
uniprot id: H2AMV1
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1071382:KAFR 0I01710
gene id: 1071382:KAFR_0I01710
uniprot id: H2B002
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071382:KAFR 0E04220
gene id: 1071382:KAFR_0E04220
uniprot id: H2AW23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071382:KAFR 0A02660
gene id: 1071382:KAFR_0A02660
uniprot id: H2AMV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1071382:KAFR 0G00430
gene id: 1071382:KAFR_0G00430
uniprot id: H2AXH6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1071382:KAFR 0I02730
gene id: 1071382:KAFR_0I02730
uniprot id: H2B0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

1071382:KAFR 0A08590
gene id: 1071382:KAFR_0A08590
uniprot id: H2APJ3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0C04920
gene id: 1071382:KAFR_0C04920
uniprot id: H2ASY3
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

1071382:KAFR 0E02070
gene id: 1071382:KAFR_0E02070
uniprot id: H2AVG0
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071382:KAFR 0B06370
gene id: 1071382:KAFR_0B06370
uniprot id: H2ARD3
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1071382:KAFR 0K00300
gene id: 1071382:KAFR_0K00300
uniprot id: H2B185
names: Similarity
messages: Belongs to the TYW1 family.

1071382:KAFR 0E01720
gene id: 1071382:KAFR_0E01720
uniprot id: H2AVC6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1071382:KAFR 0E00650
gene id: 1071382:KAFR_0E00650
uniprot id: H2AV19
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1071382:KAFR 0F03280
gene id: 1071382:KAFR_0F03280
uniprot id: H2AX24
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071382:KAFR 0F04020
gene id: 1071382:KAFR_0F04020
uniprot id: H2AX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0D02640
gene id: 1071382:KAFR_0D02640
uniprot id: H2AU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071382:KAFR 0C00890
gene id: 1071382:KAFR_0C00890
uniprot id: H2ART4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

1071382:KAFR 0F02690
gene id: 1071382:KAFR_0F02690
uniprot id: H2AWW6
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071382:KAFR 0A06880
gene id: 1071382:KAFR_0A06880
uniprot id: H2AP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

1071382:KAFR 0E00960
gene id: 1071382:KAFR_0E00960
uniprot id: H2AV50
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1071382:KAFR 0C02220
gene id: 1071382:KAFR_0C02220
uniprot id: H2AS65
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0K01010
gene id: 1071382:KAFR_0K01010
uniprot id: H2B1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071382:KAFR 0D03680
gene id: 1071382:KAFR_0D03680
uniprot id: H2AUG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0H03310
gene id: 1071382:KAFR_0H03310
uniprot id: H2AZI5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1071382:KAFR 0J02790
gene id: 1071382:KAFR_0J02790
uniprot id: H2B143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A01200
gene id: 1071382:KAFR_0A01200
uniprot id: H2AMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A08090
gene id: 1071382:KAFR_0A08090
uniprot id: H2APE3
names: Similarity
messages: Belongs to the SLA2 family.

1071382:KAFR 0G00850
gene id: 1071382:KAFR_0G00850
uniprot id: H2AXL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071382:KAFR 0L00800
gene id: 1071382:KAFR_0L00800
uniprot id: H2B237
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A07880
gene id: 1071382:KAFR_0A07880
uniprot id: H2APC2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1071382:KAFR 0K01300
gene id: 1071382:KAFR_0K01300
uniprot id: H2B1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: spindle pole

1071382:KAFR 0H03300
gene id: 1071382:KAFR_0H03300
uniprot id: H2AZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

1071382:KAFR 0A02640
gene id: 1071382:KAFR_0A02640
uniprot id: H2AMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

1071382:KAFR 0B06580
gene id: 1071382:KAFR_0B06580
uniprot id: H2ARF4
names: Similarity
messages: Belongs to the taffazin family.

1071382:KAFR 0E00160
gene id: 1071382:KAFR_0E00160
uniprot id: H2AUX0
names: Similarity
messages: Belongs to the oxoprolinase family.

1071382:KAFR 0C02780
gene id: 1071382:KAFR_0C02780
uniprot id: H2ASC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

1071382:KAFR 0H01910
gene id: 1071382:KAFR_0H01910
uniprot id: H2AZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

1071382:KAFR 0E02770
gene id: 1071382:KAFR_0E02770
uniprot id: H2AVM9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071382:KAFR 0K02350
gene id: 1071382:KAFR_0K02350
uniprot id: H2B1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

1071382:KAFR 0E02670
gene id: 1071382:KAFR_0E02670
uniprot id: H2AVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

1071382:KAFR 0B01440
gene id: 1071382:KAFR_0B01440
uniprot id: H2APZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

1071382:KAFR 0E01240
gene id: 1071382:KAFR_0E01240
uniprot id: H2AV78
names: Similarity
messages: Belongs to the WrbA family.

1071382:KAFR 0C05040
gene id: 1071382:KAFR_0C05040
uniprot id: H2ASZ5
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E03760
gene id: 1071382:KAFR_0E03760
uniprot id: H2AVX7
names: Similarity
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.

1071382:KAFR 0J00980
gene id: 1071382:KAFR_0J00980
uniprot id: H2B0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

1071382:KAFR 0K02550
gene id: 1071382:KAFR_0K02550
uniprot id: H2B1W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

1071382:KAFR 0D03090
gene id: 1071382:KAFR_0D03090
uniprot id: H2AUA7
names: Similarity
messages: Belongs to the p23/wos2 family.

1071382:KAFR 0I02710
gene id: 1071382:KAFR_0I02710
uniprot id: H2B0A0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0E02800
gene id: 1071382:KAFR_0E02800
uniprot id: H2AVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1071382:KAFR 0A06930
gene id: 1071382:KAFR_0A06930
uniprot id: H2AP28
names: Similarity
messages: Belongs to the Luc7 family.

1071382:KAFR 0H00660
gene id: 1071382:KAFR_0H00660
uniprot id: H2AYR9
names: Similarity
messages: Belongs to the GroES chaperonin family.

1071382:KAFR 0B06120
gene id: 1071382:KAFR_0B06120
uniprot id: H2ARA8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D01580
gene id: 1071382:KAFR_0D01580
uniprot id: H2ATV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071382:KAFR 0E01850
gene id: 1071382:KAFR_0E01850
uniprot id: H2AVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0B05560
gene id: 1071382:KAFR_0B05560
uniprot id: H2AR51
names: Similarity
messages: Belongs to the FGGY kinase family.

1071382:KAFR 0I01180
gene id: 1071382:KAFR_0I01180
uniprot id: H2AT50
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071382:KAFR 0A00410
gene id: 1071382:KAFR_0A00410
uniprot id: H2AM79
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071382:KAFR 0D00980
gene id: 1071382:KAFR_0D00980
uniprot id: H2ATP5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

1071382:KAFR 0L01790
gene id: 1071382:KAFR_0L01790
uniprot id: H2B2D9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0G00500
gene id: 1071382:KAFR_0G00500
uniprot id: H2AXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

1071382:KAFR 0C01060
gene id: 1071382:KAFR_0C01060
uniprot id: H2ARV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1071382:KAFR 0F04320
gene id: 1071382:KAFR_0F04320
uniprot id: H2AXC7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F01020
gene id: 1071382:KAFR_0F01020
uniprot id: H2AWE8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

1071382:KAFR 0C06510
gene id: 1071382:KAFR_0C06510
uniprot id: H2ATE7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F01270
gene id: 1071382:KAFR_0F01270
uniprot id: H2AWH3
names: Similarity
messages: Belongs to the peptidase S16 family.

1071382:KAFR 0F01770
gene id: 1071382:KAFR_0F01770
uniprot id: H2AWM4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

1071382:KAFR 0H01260
gene id: 1071382:KAFR_0H01260
uniprot id: H2AYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0D03380
gene id: 1071382:KAFR_0D03380
uniprot id: H2AUD6
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

1071382:KAFR 0A04300
gene id: 1071382:KAFR_0A04300
uniprot id: H2ANB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

1071382:KAFR 0B01060
gene id: 1071382:KAFR_0B01060
uniprot id: H2APV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1071382:KAFR 0A08540
gene id: 1071382:KAFR_0A08540
uniprot id: H2API8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071382:KAFR 0J00360
gene id: 1071382:KAFR_0J00360
uniprot id: H2B0F4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0D03980
gene id: 1071382:KAFR_0D03980
uniprot id: H2AUJ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1071382:KAFR 0I00730
gene id: 1071382:KAFR_0I00730
uniprot id: H2AZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

1071382:KAFR 0I00540
gene id: 1071382:KAFR_0I00540
uniprot id: H2AZN5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1071382:KAFR 0A02590
gene id: 1071382:KAFR_0A02590
uniprot id: H2AMU5
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

1071382:KAFR 0A03970
gene id: 1071382:KAFR_0A03970
uniprot id: H2AN82
names: Similarity
messages: Belongs to the NXF family.

1071382:KAFR 0I01660
gene id: 1071382:KAFR_0I01660
uniprot id: H2AZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

1071382:KAFR 0J01270
gene id: 1071382:KAFR_0J01270
uniprot id: H2B0P4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0G00940
gene id: 1071382:KAFR_0G00940
uniprot id: H2AXM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

1071382:KAFR 0A05790
gene id: 1071382:KAFR_0A05790
uniprot id: H2ANR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

1071382:KAFR 0I02620
gene id: 1071382:KAFR_0I02620
uniprot id: H2B091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071382:KAFR 0D03110
gene id: 1071382:KAFR_0D03110
uniprot id: H2AUA9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1071382:KAFR 0G00320
gene id: 1071382:KAFR_0G00320
uniprot id: H2AXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

1071382:KAFR 0A08440
gene id: 1071382:KAFR_0A08440
uniprot id: H2APH8
names: Similarity
messages: Belongs to the KRI1 family.

1071382:KAFR 0G00290
gene id: 1071382:KAFR_0G00290
uniprot id: H2AXG2
names: Subcellular Location Annotation
messages: Mitochondrion

1071382:KAFR 0I01190
gene id: 1071382:KAFR_0I01190
uniprot id: H2AZV0
names: Similarity
messages: Belongs to the UTP6 family.

1071382:KAFR 0G01730
gene id: 1071382:KAFR_0G01730
uniprot id: H2AXV7
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1071382:KAFR 0K01390
gene id: 1071382:KAFR_0K01390
uniprot id: H2B1J3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

1071382:KAFR 0A03190
gene id: 1071382:KAFR_0A03190
uniprot id: H2AN04
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01980
gene id: 1071382:KAFR_0H01980
uniprot id: H2AZ51
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0E01480
gene id: 1071382:KAFR_0E01480
uniprot id: H2AVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1071382:KAFR 0C05870
gene id: 1071382:KAFR_0C05870
uniprot id: H2AT78
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071382:KAFR 0D05060
gene id: 1071382:KAFR_0D05060
uniprot id: H2AUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

1071382:KAFR 0A00660
gene id: 1071382:KAFR_0A00660
uniprot id: H2AMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrial mRNA stabilization factor.
messages: Mitochondrion inner membrane

1071382:KAFR 0C04940
gene id: 1071382:KAFR_0C04940
uniprot id: H2ASY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
messages: Nucleus

1071382:KAFR 0B02640
gene id: 1071382:KAFR_0B02640
uniprot id: H2AQB1
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1071382:KAFR 0I00940
gene id: 1071382:KAFR_0I00940
uniprot id: H2AZS5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1071382:KAFR 0K02090
gene id: 1071382:KAFR_0K02090
uniprot id: H2B1R3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0E03140
gene id: 1071382:KAFR_0E03140
uniprot id: H2AVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

1071382:KAFR 0C03880
gene id: 1071382:KAFR_0C03880
uniprot id: H2ASM9
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1071382:KAFR 0B06700
gene id: 1071382:KAFR_0B06700
uniprot id: H2ARG7
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0H03370
gene id: 1071382:KAFR_0H03370
uniprot id: H2AYH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

1071382:KAFR 0J00780
gene id: 1071382:KAFR_0J00780
uniprot id: H2B0J6
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071382:KAFR 0I01170
gene id: 1071382:KAFR_0I01170
uniprot id: H2AZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0C04580
gene id: 1071382:KAFR_0C04580
uniprot id: H2ASU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0K01800
gene id: 1071382:KAFR_0K01800
uniprot id: H2B1N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

1071382:KAFR 0J00520
gene id: 1071382:KAFR_0J00520
uniprot id: H2B0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

1071382:KAFR 0F00710
gene id: 1071382:KAFR_0F00710
uniprot id: H2AWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

1071382:KAFR 0C04570
gene id: 1071382:KAFR_0C04570
uniprot id: H2ASU8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1071382:KAFR 0F02240
gene id: 1071382:KAFR_0F02240
uniprot id: H2AWS1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1071382:KAFR 0C06290
gene id: 1071382:KAFR_0C06290
uniprot id: H2ATC5
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1071382:KAFR 0A07140
gene id: 1071382:KAFR_0A07140
uniprot id: H2AP48
names: Similarity
messages: Belongs to the Tango6 family.

1071382:KAFR 0I02670
gene id: 1071382:KAFR_0I02670
uniprot id: H2B096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

1071382:KAFR 0A04690
gene id: 1071382:KAFR_0A04690
uniprot id: H2ANF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1071382:KAFR 0C03870
gene id: 1071382:KAFR_0C03870
uniprot id: H2ASM8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D05000
gene id: 1071382:KAFR_0D05000
uniprot id: H2AUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0D03470
gene id: 1071382:KAFR_0D03470
uniprot id: H2AUE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

1071382:KAFR 0A05710
gene id: 1071382:KAFR_0A05710
uniprot id: H2ANQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

1071382:KAFR 0K00540
gene id: 1071382:KAFR_0K00540
uniprot id: H2B1A9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071382:KAFR 0B05080
gene id: 1071382:KAFR_0B05080
uniprot id: H2AR04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1071382:KAFR 0E00790
gene id: 1071382:KAFR_0E00790
uniprot id: H2AV33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1071382:KAFR 0C00720
gene id: 1071382:KAFR_0C00720
uniprot id: H2ARR7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0H01440
gene id: 1071382:KAFR_0H01440
uniprot id: H2AYZ8
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

1071382:KAFR 0D00910
gene id: 1071382:KAFR_0D00910
uniprot id: H2ATN8
names: Similarity
messages: Belongs to the FYV7 family.

1071382:KAFR 0C00400
gene id: 1071382:KAFR_0C00400
uniprot id: H2ARN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0A00860
gene id: 1071382:KAFR_0A00860
uniprot id: H2AMC4
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1071382:KAFR 0A05210
gene id: 1071382:KAFR_0A05210
uniprot id: H2ANK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

1071382:KAFR 0D00230
gene id: 1071382:KAFR_0D00230
uniprot id: H2ATG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

1071382:KAFR 0I01520
gene id: 1071382:KAFR_0I01520
uniprot id: H2AZY3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

1071382:KAFR 0D00560
gene id: 1071382:KAFR_0D00560
uniprot id: H2ATK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1071382:KAFR 0E02960
gene id: 1071382:KAFR_0E02960
uniprot id: H2AVP8
names: Similarity
messages: Belongs to the CWC21 family.

1071382:KAFR 0B02260
gene id: 1071382:KAFR_0B02260
uniprot id: H2AQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

1071382:KAFR 0A01650
gene id: 1071382:KAFR_0A01650
uniprot id: H2AMK3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1071382:KAFR 0E02100
gene id: 1071382:KAFR_0E02100
uniprot id: H2AVG3
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071382:KAFR 0A01710
gene id: 1071382:KAFR_0A01710
uniprot id: H2AMK9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0I02440
gene id: 1071382:KAFR_0I02440
uniprot id: H2B073
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0F01200
gene id: 1071382:KAFR_0F01200
uniprot id: H2AWG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

1071382:KAFR 0F02850
gene id: 1071382:KAFR_0F02850
uniprot id: H2AWY1
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C01210
gene id: 1071382:KAFR_0C01210
uniprot id: H2ARW6
names: Similarity
messages: Belongs to the BRX1 family.

1071382:KAFR 0E03390
gene id: 1071382:KAFR_0E03390
uniprot id: H2AVU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1071382:KAFR 0F03900
gene id: 1071382:KAFR_0F03900
uniprot id: H2AX86
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071382:KAFR 0K01260
gene id: 1071382:KAFR_0K01260
uniprot id: H2B1I0
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071382:KAFR 0A08060
gene id: 1071382:KAFR_0A08060
uniprot id: H2APE0
names: Similarity
messages: Belongs to the NARF family.

1071382:KAFR 0H02880
gene id: 1071382:KAFR_0H02880
uniprot id: H2AZE1
names: Similarity
messages: Belongs to the small Tim family.

1071382:KAFR 0A03370
gene id: 1071382:KAFR_0A03370
uniprot id: H2AN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0F03330
gene id: 1071382:KAFR_0F03330
uniprot id: H2AX29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

1071382:KAFR 0J01800
gene id: 1071382:KAFR_0J01800
uniprot id: H2B0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0B06990
gene id: 1071382:KAFR_0B06990
uniprot id: H2ARJ7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E02970
gene id: 1071382:KAFR_0E02970
uniprot id: H2AVP9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0A08520
gene id: 1071382:KAFR_0A08520
uniprot id: H2API6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0B04700
gene id: 1071382:KAFR_0B04700
uniprot id: H2AQW7
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

1071382:KAFR 0I00160
gene id: 1071382:KAFR_0I00160
uniprot id: H2AZJ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0A04090
gene id: 1071382:KAFR_0A04090
uniprot id: H2AN94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1071382:KAFR 0J02830
gene id: 1071382:KAFR_0J02830
uniprot id: H2B147
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

1071382:KAFR 0I02600
gene id: 1071382:KAFR_0I02600
uniprot id: H2B089
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0I00380
gene id: 1071382:KAFR_0I00380
uniprot id: H2AZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

1071382:KAFR 0J01290
gene id: 1071382:KAFR_0J01290
uniprot id: H2B0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0A08370
gene id: 1071382:KAFR_0A08370
uniprot id: H2APH1
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

1071382:KAFR 0B05350
gene id: 1071382:KAFR_0B05350
uniprot id: H2AR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

1071382:KAFR 0F01910
gene id: 1071382:KAFR_0F01910
uniprot id: H2AWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.

1071382:KAFR 0A00910
gene id: 1071382:KAFR_0A00910
uniprot id: H2AMC9
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

1071382:KAFR 0B02710
gene id: 1071382:KAFR_0B02710
uniprot id: H2AQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

1071382:KAFR 0E01120
gene id: 1071382:KAFR_0E01120
uniprot id: H2AV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0B02900
gene id: 1071382:KAFR_0B02900
uniprot id: H2AQD7
names: Similarity
messages: Belongs to the LCL2 family.

1071382:KAFR 0C04130
gene id: 1071382:KAFR_0C04130
uniprot id: H2ASQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0K00270
gene id: 1071382:KAFR_0K00270
uniprot id: H2B182
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1071382:KAFR 0C02270
gene id: 1071382:KAFR_0C02270
uniprot id: H2AS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071382:KAFR 0L01200
gene id: 1071382:KAFR_0L01200
uniprot id: H2B278
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0C04850
gene id: 1071382:KAFR_0C04850
uniprot id: H2ASX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

1071382:KAFR 0K01150
gene id: 1071382:KAFR_0K01150
uniprot id: H2B1H0
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071382:KAFR 0L00940
gene id: 1071382:KAFR_0L00940
uniprot id: H2B252
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

1071382:KAFR 0C06420
gene id: 1071382:KAFR_0C06420
uniprot id: H2ATD8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0I01630
gene id: 1071382:KAFR_0I01630
uniprot id: H2AZZ4
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

1071382:KAFR 0J01200
gene id: 1071382:KAFR_0J01200
uniprot id: H2B0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071382:KAFR 0G03540
gene id: 1071382:KAFR_0G03540
uniprot id: H2AYD6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1071382:KAFR 0A06500
gene id: 1071382:KAFR_0A06500
uniprot id: H2ANY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0C04480
gene id: 1071382:KAFR_0C04480
uniprot id: H2AST9
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0F03590
gene id: 1071382:KAFR_0F03590
uniprot id: H2AX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

1071382:KAFR 0E04180
gene id: 1071382:KAFR_0E04180
uniprot id: H2AW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

1071382:KAFR 0B04680
gene id: 1071382:KAFR_0B04680
uniprot id: H2AQW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0E01020
gene id: 1071382:KAFR_0E01020
uniprot id: H2AV56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A05650
gene id: 1071382:KAFR_0A05650
uniprot id: H2ANQ0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1071382:KAFR 0I00660
gene id: 1071382:KAFR_0I00660
uniprot id: H2AZP7
names: Similarity
messages: Belongs to the MGR2 family.

1071382:KAFR 0H03090
gene id: 1071382:KAFR_0H03090
uniprot id: H2AZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

1071382:KAFR 0F02270
gene id: 1071382:KAFR_0F02270
uniprot id: H2AWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0E03600
gene id: 1071382:KAFR_0E03600
uniprot id: H2AVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.
messages: nucleolus

1071382:KAFR 0H03360
gene id: 1071382:KAFR_0H03360
uniprot id: H2AZJ0
names: Similarity
messages: Belongs to the PIGH family.

1071382:KAFR 0H01990
gene id: 1071382:KAFR_0H01990
uniprot id: H2AZ52
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1071382:KAFR 0L01740
gene id: 1071382:KAFR_0L01740
uniprot id: H2B2D4
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071382:KAFR 0D01700
gene id: 1071382:KAFR_0D01700
uniprot id: H2ATW7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L01850
gene id: 1071382:KAFR_0L01850
uniprot id: H2B2E5
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E03740
gene id: 1071382:KAFR_0E03740
uniprot id: H2AVX5
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

1071382:KAFR 0E01050
gene id: 1071382:KAFR_0E01050
uniprot id: H2AV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1071382:KAFR 0B06600
gene id: 1071382:KAFR_0B06600
uniprot id: H2ARF6
names: Similarity
messages: Belongs to the RRP15 family.

1071382:KAFR 0F03420
gene id: 1071382:KAFR_0F03420
uniprot id: H2AX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1071382:KAFR 0I02830
gene id: 1071382:KAFR_0I02830
uniprot id: H2B0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0D03530
gene id: 1071382:KAFR_0D03530
uniprot id: H2AUF1
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A00350
gene id: 1071382:KAFR_0A00350
uniprot id: H2AM73
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0C00820
gene id: 1071382:KAFR_0C00820
uniprot id: H2ARS7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A06860
gene id: 1071382:KAFR_0A06860
uniprot id: H2AP21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

1071382:KAFR 0B06625
gene id: 1071382:KAFR_0B06625
uniprot id: H2ARF9
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0C03010
gene id: 1071382:KAFR_0C03010
uniprot id: H2ASE4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

1071382:KAFR 0E04400
gene id: 1071382:KAFR_0E04400
uniprot id: H2AW40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0H02580
gene id: 1071382:KAFR_0H02580
uniprot id: H2AZB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

1071382:KAFR 0L00990
gene id: 1071382:KAFR_0L00990
uniprot id: H2B257
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

1071382:KAFR 0C04300
gene id: 1071382:KAFR_0C04300
uniprot id: H2ASS0
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1071382:KAFR 0G01170
gene id: 1071382:KAFR_0G01170
uniprot id: H2AXQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A00590
gene id: 1071382:KAFR_0A00590
uniprot id: H2AM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: telomere

1071382:KAFR 0D02920
gene id: 1071382:KAFR_0D02920
uniprot id: H2AU90
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

1071382:KAFR 0C03090
gene id: 1071382:KAFR_0C03090
uniprot id: H2ASF1
names: Subcellular Location Annotation
messages: Nucleus membrane

1071382:KAFR 0L01640
gene id: 1071382:KAFR_0L01640
uniprot id: H2B2C4
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0K01940
gene id: 1071382:KAFR_0K01940
uniprot id: H2B1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1071382:KAFR 0G00110
gene id: 1071382:KAFR_0G00110
uniprot id: H2AXE4
names: Similarity
messages: Belongs to the BMT family.

1071382:KAFR 0D01200
gene id: 1071382:KAFR_0D01200
uniprot id: H2ATR6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

1071382:KAFR 0F03760
gene id: 1071382:KAFR_0F03760
uniprot id: H2AX72
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

1071382:KAFR 0I00420
gene id: 1071382:KAFR_0I00420
uniprot id: H2AZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

1071382:KAFR 0C02090
gene id: 1071382:KAFR_0C02090
uniprot id: H2AS52
names: Subcellular Location Annotation
messages: nuclear pore complex

1071382:KAFR 0A05070
gene id: 1071382:KAFR_0A05070
uniprot id: H2ANJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D04910
gene id: 1071382:KAFR_0D04910
uniprot id: H2AUT8
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0E00220
gene id: 1071382:KAFR_0E00220
uniprot id: H2AUX6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

1071382:KAFR 0C01110
gene id: 1071382:KAFR_0C01110
uniprot id: H2ARV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: kinetochore

1071382:KAFR 0E02980
gene id: 1071382:KAFR_0E02980
uniprot id: H2AVQ0
names: Similarity
messages: Belongs to the TTC4 family.

1071382:KAFR 0H00300
gene id: 1071382:KAFR_0H00300
uniprot id: H2AYN3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0B04360
gene id: 1071382:KAFR_0B04360
uniprot id: H2AQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0H00560
gene id: 1071382:KAFR_0H00560
uniprot id: H2AYQ9
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071382:KAFR 0B06590
gene id: 1071382:KAFR_0B06590
uniprot id: H2ARF5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071382:KAFR 0E01560
gene id: 1071382:KAFR_0E01560
uniprot id: H2AVB0
names: Similarity
messages: Belongs to the RCAN family.

1071382:KAFR 0E03260
gene id: 1071382:KAFR_0E03260
uniprot id: H2AVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0B04140
gene id: 1071382:KAFR_0B04140
uniprot id: H2AQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

1071382:KAFR 0B03440
gene id: 1071382:KAFR_0B03440
uniprot id: H2AQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

1071382:KAFR 0F00670
gene id: 1071382:KAFR_0F00670
uniprot id: H2AWB4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1071382:KAFR 0A05240
gene id: 1071382:KAFR_0A05240
uniprot id: H2ANK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A06380
gene id: 1071382:KAFR_0A06380
uniprot id: H2ANX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071382:KAFR 0A02330
gene id: 1071382:KAFR_0A02330
uniprot id: H2AMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

1071382:KAFR 0E03460
gene id: 1071382:KAFR_0E03460
uniprot id: H2AVU8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H02000
gene id: 1071382:KAFR_0H02000
uniprot id: H2AZ53
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

1071382:KAFR 0B03630
gene id: 1071382:KAFR_0B03630
uniprot id: H2AQL0
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

1071382:KAFR 0F04120
gene id: 1071382:KAFR_0F04120
uniprot id: H2AXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1071382:KAFR 0B06490
gene id: 1071382:KAFR_0B06490
uniprot id: H2ARE5
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

1071382:KAFR 0H00700
gene id: 1071382:KAFR_0H00700
uniprot id: H2AYS3
names: Similarity
messages: Belongs to the PHF5 family.

1071382:KAFR 0F04130
gene id: 1071382:KAFR_0F04130
uniprot id: H2AXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

1071382:KAFR 0I00220
gene id: 1071382:KAFR_0I00220
uniprot id: H2AZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071382:KAFR 0L01610
gene id: 1071382:KAFR_0L01610
uniprot id: H2B2C1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071382:KAFR 0J00230
gene id: 1071382:KAFR_0J00230
uniprot id: H2B0E1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

1071382:KAFR 0E01280
gene id: 1071382:KAFR_0E01280
uniprot id: H2AV82
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

1071382:KAFR 0D01330
gene id: 1071382:KAFR_0D01330
uniprot id: H2ATS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

1071382:KAFR 0I02130
gene id: 1071382:KAFR_0I02130
uniprot id: H2B043
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1071382:KAFR 0D04020
gene id: 1071382:KAFR_0D04020
uniprot id: H2AUK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0F02490
gene id: 1071382:KAFR_0F02490
uniprot id: H2AWU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0B03060
gene id: 1071382:KAFR_0B03060
uniprot id: H2AQF2
names: Similarity
messages: Belongs to the VPS37 family.

1071382:KAFR 0A08260
gene id: 1071382:KAFR_0A08260
uniprot id: H2APG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071382:KAFR 0J00860
gene id: 1071382:KAFR_0J00860
uniprot id: H2B0K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1071382:KAFR 0A06570
gene id: 1071382:KAFR_0A06570
uniprot id: H2ANZ2
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

1071382:KAFR 0J00630
gene id: 1071382:KAFR_0J00630
uniprot id: H2B0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

1071382:KAFR 0H03710
gene id: 1071382:KAFR_0H03710
uniprot id: H2AYK4
names: Similarity
messages: Belongs to the RPAP1 family.

1071382:KAFR 0D03430
gene id: 1071382:KAFR_0D03430
uniprot id: H2AUE1
names: Similarity
messages: Belongs to the PITHD1 family.

1071382:KAFR 0B03690
gene id: 1071382:KAFR_0B03690
uniprot id: H2AQL6
names: Similarity
messages: Belongs to the PPase family.

1071382:KAFR 0H02330
gene id: 1071382:KAFR_0H02330
uniprot id: H2AZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1071382:KAFR 0I01080
gene id: 1071382:KAFR_0I01080
uniprot id: H2AZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

1071382:KAFR 0J02090
gene id: 1071382:KAFR_0J02090
uniprot id: H2B0X3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1071382:KAFR 0E04420
gene id: 1071382:KAFR_0E04420
uniprot id: H2AW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

1071382:KAFR 0E01250
gene id: 1071382:KAFR_0E01250
uniprot id: H2AV79
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0K01640
gene id: 1071382:KAFR_0K01640
uniprot id: H2B1L8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A04050
gene id: 1071382:KAFR_0A04050
uniprot id: H2AN90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

1071382:KAFR 0J02850
gene id: 1071382:KAFR_0J02850
uniprot id: H2B149
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

1071382:KAFR 0H00150
gene id: 1071382:KAFR_0H00150
uniprot id: H2AYL8
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0C00240
gene id: 1071382:KAFR_0C00240
uniprot id: H2ARM0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1071382:KAFR 0D04410
gene id: 1071382:KAFR_0D04410
uniprot id: H2AUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071382:KAFR 0C05550
gene id: 1071382:KAFR_0C05550
uniprot id: H2AT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1071382:KAFR 0D03180
gene id: 1071382:KAFR_0D03180
uniprot id: H2AUB6
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

1071382:KAFR 0F03460
gene id: 1071382:KAFR_0F03460
uniprot id: H2AX42
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0F01990
gene id: 1071382:KAFR_0F01990
uniprot id: H2AWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A04030
gene id: 1071382:KAFR_0A04030
uniprot id: H2AN88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1071382:KAFR 0G02000
gene id: 1071382:KAFR_0G02000
uniprot id: H2AXY4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071382:KAFR 0A00500
gene id: 1071382:KAFR_0A00500
uniprot id: H2AM88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0A05980
gene id: 1071382:KAFR_0A05980
uniprot id: H2AYA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1071382:KAFR 0F00480
gene id: 1071382:KAFR_0F00480
uniprot id: H2AW95
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

1071382:KAFR 0I00710
gene id: 1071382:KAFR_0I00710
uniprot id: H2AZQ2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H00240
gene id: 1071382:KAFR_0H00240
uniprot id: H2AYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1071382:KAFR 0I01300
gene id: 1071382:KAFR_0I01300
uniprot id: H2AZW1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E02750
gene id: 1071382:KAFR_0E02750
uniprot id: H2AVM7
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

1071382:KAFR 0H03220
gene id: 1071382:KAFR_0H03220
uniprot id: H2AZH6
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0E03820
gene id: 1071382:KAFR_0E03820
uniprot id: H2AVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1071382:KAFR 0D04400
gene id: 1071382:KAFR_0D04400
uniprot id: H2AUN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

1071382:KAFR 0K02160
gene id: 1071382:KAFR_0K02160
uniprot id: H2B1S0
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

1071382:KAFR 0K01900
gene id: 1071382:KAFR_0K01900
uniprot id: H2B1P4
names: Similarity
messages: Belongs to the WD repeat rae1 family.

1071382:KAFR 0B00550
gene id: 1071382:KAFR_0B00550
uniprot id: H2APQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0B05170
gene id: 1071382:KAFR_0B05170
uniprot id: H2AR13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

1071382:KAFR 0H02995
gene id: 1071382:KAFR_0H02995
uniprot id: H2AZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071382:KAFR 0F02550
gene id: 1071382:KAFR_0F02550
uniprot id: H2AWV2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1071382:KAFR 0G02220
gene id: 1071382:KAFR_0G02220
uniprot id: H2AY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

1071382:KAFR 0I02200
gene id: 1071382:KAFR_0I02200
uniprot id: H2B049
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1071382:KAFR 0F01730
gene id: 1071382:KAFR_0F01730
uniprot id: H2AWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

1071382:KAFR 0F03240
gene id: 1071382:KAFR_0F03240
uniprot id: H2AX20
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1071382:KAFR 0A07520
gene id: 1071382:KAFR_0A07520
uniprot id: H2AP86
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

1071382:KAFR 0F03710
gene id: 1071382:KAFR_0F03710
uniprot id: H2AX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

1071382:KAFR 0B00910
gene id: 1071382:KAFR_0B00910
uniprot id: H2APT9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0B06480
gene id: 1071382:KAFR_0B06480
uniprot id: H2ARE4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C01730
gene id: 1071382:KAFR_0C01730
uniprot id: H2AS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

1071382:KAFR 0G00600
gene id: 1071382:KAFR_0G00600
uniprot id: H2AXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

1071382:KAFR 0A05110
gene id: 1071382:KAFR_0A05110
uniprot id: H2ANJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0J00240
gene id: 1071382:KAFR_0J00240
uniprot id: H2B0E2
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

1071382:KAFR 0A03720
gene id: 1071382:KAFR_0A03720
uniprot id: H2AN57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

1071382:KAFR 0G00710
gene id: 1071382:KAFR_0G00710
uniprot id: H2AXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D01560
gene id: 1071382:KAFR_0D01560
uniprot id: H2ATV2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B04720
gene id: 1071382:KAFR_0B04720
uniprot id: H2AQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071382:KAFR 0F01670
gene id: 1071382:KAFR_0F01670
uniprot id: H2AWL4
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

1071382:KAFR 0C01720
gene id: 1071382:KAFR_0C01720
uniprot id: H2AS15
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1071382:KAFR 0A02840
gene id: 1071382:KAFR_0A02840
uniprot id: H2AMX0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A02570
gene id: 1071382:KAFR_0A02570
uniprot id: H2AMU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

1071382:KAFR 0B03910
gene id: 1071382:KAFR_0B03910
uniprot id: H2AQN7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

1071382:KAFR 0B05690
gene id: 1071382:KAFR_0B05690
uniprot id: H2AR65
names: Similarity
messages: Belongs to the dopey family.

1071382:KAFR 0C04330
gene id: 1071382:KAFR_0C04330
uniprot id: H2ASS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071382:KAFR 0I00320
gene id: 1071382:KAFR_0I00320
uniprot id: H2AZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

1071382:KAFR 0A03810
gene id: 1071382:KAFR_0A03810
uniprot id: H2AN66
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.

1071382:KAFR 0E00900
gene id: 1071382:KAFR_0E00900
uniprot id: H2AV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

1071382:KAFR 0D00600
gene id: 1071382:KAFR_0D00600
uniprot id: H2ATK7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1071382:KAFR 0A00760
gene id: 1071382:KAFR_0A00760
uniprot id: H2AMB4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1071382:KAFR 0D03510
gene id: 1071382:KAFR_0D03510
uniprot id: H2AUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

1071382:KAFR 0F02980
gene id: 1071382:KAFR_0F02980
uniprot id: H2AWZ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071382:KAFR 0A04180
gene id: 1071382:KAFR_0A04180
uniprot id: H2ANA3
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

1071382:KAFR 0B04920
gene id: 1071382:KAFR_0B04920
uniprot id: H2AQY8
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071382:KAFR 0A01170
gene id: 1071382:KAFR_0A01170
uniprot id: H2AMF6
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071382:KAFR 0E01590
gene id: 1071382:KAFR_0E01590
uniprot id: H2AVB3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0I00270
gene id: 1071382:KAFR_0I00270
uniprot id: H2AZK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1071382:KAFR 0H02760
gene id: 1071382:KAFR_0H02760
uniprot id: H2AZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

1071382:KAFR 0G01270
gene id: 1071382:KAFR_0G01270
uniprot id: H2AXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

1071382:KAFR 0B01160
gene id: 1071382:KAFR_0B01160
uniprot id: H2APW5
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

1071382:KAFR 0H00380
gene id: 1071382:KAFR_0H00380
uniprot id: H2AYP1
names: Similarity
messages: Belongs to the RNase Z family.

1071382:KAFR 0C05090
gene id: 1071382:KAFR_0C05090
uniprot id: H2AT00
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0G01690
gene id: 1071382:KAFR_0G01690
uniprot id: H2AXV3
names: Similarity
messages: Belongs to the FES1 family.

1071382:KAFR 0D05010
gene id: 1071382:KAFR_0D05010
uniprot id: H2AUU8
names: Similarity
messages: Belongs to the peptidase M18 family.

1071382:KAFR 0B01350
gene id: 1071382:KAFR_0B01350
uniprot id: H2APY4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1071382:KAFR 0D00500
gene id: 1071382:KAFR_0D00500
uniprot id: H2ATJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0F01610
gene id: 1071382:KAFR_0F01610
uniprot id: H2AWK8
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1071382:KAFR 0E04210
gene id: 1071382:KAFR_0E04210
uniprot id: H2AW22
names: Similarity
messages: Belongs to the hexokinase family.

1071382:KAFR 0I00850
gene id: 1071382:KAFR_0I00850
uniprot id: H2AZR6
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

1071382:KAFR 0A03420
gene id: 1071382:KAFR_0A03420
uniprot id: H2AN27
names: Similarity
messages: Belongs to the phospholipase D family.

1071382:KAFR 0A01460
gene id: 1071382:KAFR_0A01460
uniprot id: H2AMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

1071382:KAFR 0A06460
gene id: 1071382:KAFR_0A06460
uniprot id: H2ANY1
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1071382:KAFR 0E00550
gene id: 1071382:KAFR_0E00550
uniprot id: H2AV09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071382:KAFR 0F01240
gene id: 1071382:KAFR_0F01240
uniprot id: H2AWH0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C06540
gene id: 1071382:KAFR_0C06540
uniprot id: H2ATF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

1071382:KAFR 0D00220
gene id: 1071382:KAFR_0D00220
uniprot id: H2ATG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071382:KAFR 0F01470
gene id: 1071382:KAFR_0F01470
uniprot id: H2AWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071382:KAFR 0D02850
gene id: 1071382:KAFR_0D02850
uniprot id: H2AU83
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

1071382:KAFR 0J02120
gene id: 1071382:KAFR_0J02120
uniprot id: H2B0X6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D02680
gene id: 1071382:KAFR_0D02680
uniprot id: H2AU66
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1071382:KAFR 0A01670
gene id: 1071382:KAFR_0A01670
uniprot id: H2AMK5
names: Similarity
messages: Belongs to the esterase D family.

1071382:KAFR 0D01450
gene id: 1071382:KAFR_0D01450
uniprot id: H2ATU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B00410
gene id: 1071382:KAFR_0B00410
uniprot id: H2APP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Membrane

1071382:KAFR 0A01640
gene id: 1071382:KAFR_0A01640
uniprot id: H2AMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

1071382:KAFR 0A02500
gene id: 1071382:KAFR_0A02500
uniprot id: H2AMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B00470
gene id: 1071382:KAFR_0B00470
uniprot id: H2APP7
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1071382:KAFR 0K00650
gene id: 1071382:KAFR_0K00650
uniprot id: H2B1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0C02350
gene id: 1071382:KAFR_0C02350
uniprot id: H2AS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0H02270
gene id: 1071382:KAFR_0H02270
uniprot id: H2AZ80
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

1071382:KAFR 0G00670
gene id: 1071382:KAFR_0G00670
uniprot id: H2AXK0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1071382:KAFR 0K01130
gene id: 1071382:KAFR_0K01130
uniprot id: H2B1G8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H03200
gene id: 1071382:KAFR_0H03200
uniprot id: H2AZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

1071382:KAFR 0F00790
gene id: 1071382:KAFR_0F00790
uniprot id: H2AWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

1071382:KAFR 0D02230
gene id: 1071382:KAFR_0D02230
uniprot id: H2AYM5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

1071382:KAFR 0H02030
gene id: 1071382:KAFR_0H02030
uniprot id: H2AZ56
names: Similarity
messages: Belongs to the peptidase M16 family.

1071382:KAFR 0B03050
gene id: 1071382:KAFR_0B03050
uniprot id: H2AQF1
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

1071382:KAFR 0G01010
gene id: 1071382:KAFR_0G01010
uniprot id: H2AXN4
names: Similarity
messages: Belongs to the TMEM14 family.

1071382:KAFR 0A07190
gene id: 1071382:KAFR_0A07190
uniprot id: H2AP53
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1071382:KAFR 0H01710
gene id: 1071382:KAFR_0H01710
uniprot id: H2AZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0J00670
gene id: 1071382:KAFR_0J00670
uniprot id: H2B0I5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L02080
gene id: 1071382:KAFR_0L02080
uniprot id: H2B2G9
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0C01880
gene id: 1071382:KAFR_0C01880
uniprot id: H2AS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0J01020
gene id: 1071382:KAFR_0J01020
uniprot id: H2B0M0
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

1071382:KAFR 0J02100
gene id: 1071382:KAFR_0J02100
uniprot id: H2B0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

1071382:KAFR 0D04870
gene id: 1071382:KAFR_0D04870
uniprot id: H2AUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

1071382:KAFR 0B00680
gene id: 1071382:KAFR_0B00680
uniprot id: H2APR7
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

1071382:KAFR 0B06400
gene id: 1071382:KAFR_0B06400
uniprot id: H2ARD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

1071382:KAFR 0D03300
gene id: 1071382:KAFR_0D03300
uniprot id: H2AUC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

1071382:KAFR 0K01360
gene id: 1071382:KAFR_0K01360
uniprot id: H2B1J0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K01620
gene id: 1071382:KAFR_0K01620
uniprot id: H2B1L6
names: Similarity
messages: Belongs to the TEL2 family.

1071382:KAFR 0J02200
gene id: 1071382:KAFR_0J02200
uniprot id: H2B0Y4
names: Similarity
messages: Belongs to the Tom22 family.

1071382:KAFR 0B03610
gene id: 1071382:KAFR_0B03610
uniprot id: H2AQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

1071382:KAFR 0B04970
gene id: 1071382:KAFR_0B04970
uniprot id: H2AQZ3
names: Subcellular Location Annotation
messages: nuclear pore complex

1071382:KAFR 0E00480
gene id: 1071382:KAFR_0E00480
uniprot id: H2AV02
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1071382:KAFR 0B01090
gene id: 1071382:KAFR_0B01090
uniprot id: H2APV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1071382:KAFR 0D05090
gene id: 1071382:KAFR_0D05090
uniprot id: H2AUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B05490
gene id: 1071382:KAFR_0B05490
uniprot id: H2AR44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1071382:KAFR 0A07760
gene id: 1071382:KAFR_0A07760
uniprot id: H2APB0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1071382:KAFR 0C04340
gene id: 1071382:KAFR_0C04340
uniprot id: H2ASS4
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

1071382:KAFR 0K00580
gene id: 1071382:KAFR_0K00580
uniprot id: H2B1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071382:KAFR 0C02110
gene id: 1071382:KAFR_0C02110
uniprot id: H2AS54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

1071382:KAFR 0F00540
gene id: 1071382:KAFR_0F00540
uniprot id: H2AWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B02480
gene id: 1071382:KAFR_0B02480
uniprot id: H2AQ96
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1071382:KAFR 0D01570
gene id: 1071382:KAFR_0D01570
uniprot id: H2ATV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

1071382:KAFR 0C03070
gene id: 1071382:KAFR_0C03070
uniprot id: H2ASE9
names: Similarity
messages: Belongs to the CWC26 family.

1071382:KAFR 0E00640
gene id: 1071382:KAFR_0E00640
uniprot id: H2AV18
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1071382:KAFR 0F01450
gene id: 1071382:KAFR_0F01450
uniprot id: H2AWJ1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

1071382:KAFR 0C06030
gene id: 1071382:KAFR_0C06030
uniprot id: H2AT94
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1071382:KAFR 0A04490
gene id: 1071382:KAFR_0A04490
uniprot id: H2AND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0I01830
gene id: 1071382:KAFR_0I01830
uniprot id: H2B013
names: Similarity
messages: Belongs to the RutC family.

1071382:KAFR 0F02840
gene id: 1071382:KAFR_0F02840
uniprot id: H2AWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

1071382:KAFR 0B02970
gene id: 1071382:KAFR_0B02970
uniprot id: H2AQE3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01270
gene id: 1071382:KAFR_0A01270
uniprot id: H2B0P7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0B03200
gene id: 1071382:KAFR_0B03200
uniprot id: H2AQG6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1071382:KAFR 0B00660
gene id: 1071382:KAFR_0B00660
uniprot id: H2APR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D01440
gene id: 1071382:KAFR_0D01440
uniprot id: H2ATU0
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1071382:KAFR 0B04860
gene id: 1071382:KAFR_0B04860
uniprot id: H2AQY2
names: Similarity
messages: Belongs to the lipin family.

1071382:KAFR 0F02760
gene id: 1071382:KAFR_0F02760
uniprot id: H2AWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

1071382:KAFR 0C01200
gene id: 1071382:KAFR_0C01200
uniprot id: H2ARW5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G02120
gene id: 1071382:KAFR_0G02120
uniprot id: H2AXZ6
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1071382:KAFR 0C01470
gene id: 1071382:KAFR_0C01470
uniprot id: H2ARZ0
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

1071382:KAFR 0B00290
gene id: 1071382:KAFR_0B00290
uniprot id: H2APM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

1071382:KAFR 0L01030
gene id: 1071382:KAFR_0L01030
uniprot id: H2B261
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0H03440
gene id: 1071382:KAFR_0H03440
uniprot id: H2AYH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1071382:KAFR 0D00410
gene id: 1071382:KAFR_0D00410
uniprot id: H2ATI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

1071382:KAFR 0F00940
gene id: 1071382:KAFR_0F00940
uniprot id: H2AWE1
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition.

1071382:KAFR 0E02300
gene id: 1071382:KAFR_0E02300
uniprot id: H2AVI3
names: Similarity
messages: Belongs to the enolase family.

1071382:KAFR 0C06200
gene id: 1071382:KAFR_0C06200
uniprot id: H2ATB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

1071382:KAFR 0K02240
gene id: 1071382:KAFR_0K02240
uniprot id: H2B1S8
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

1071382:KAFR 0B05870
gene id: 1071382:KAFR_0B05870
uniprot id: H2AR83
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

1071382:KAFR 0C03790
gene id: 1071382:KAFR_0C03790
uniprot id: H2ASM0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1071382:KAFR 0D03970
gene id: 1071382:KAFR_0D03970
uniprot id: H2AUJ5
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C03570
gene id: 1071382:KAFR_0C03570
uniprot id: H2ASJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071382:KAFR 0I02580
gene id: 1071382:KAFR_0I02580
uniprot id: H2B087
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B00540
gene id: 1071382:KAFR_0B00540
uniprot id: H2APQ3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1071382:KAFR 0D01170
gene id: 1071382:KAFR_0D01170
uniprot id: H2ATR3
names: Similarity
messages: Belongs to the MAK16 family.

1071382:KAFR 0B00980
gene id: 1071382:KAFR_0B00980
uniprot id: H2APU6
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0G03470
gene id: 1071382:KAFR_0G03470
uniprot id: H2AYC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

1071382:KAFR 0A05400
gene id: 1071382:KAFR_0A05400
uniprot id: H2ANM5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B03480
gene id: 1071382:KAFR_0B03480
uniprot id: H2AQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

1071382:KAFR 0C00540
gene id: 1071382:KAFR_0C00540
uniprot id: H2ARP9
names: Similarity
messages: Belongs to the WrbA family.

1071382:KAFR 0B05230
gene id: 1071382:KAFR_0B05230
uniprot id: H2AR19
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C04210
gene id: 1071382:KAFR_0C04210
uniprot id: H2ASR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

1071382:KAFR 0G00360
gene id: 1071382:KAFR_0G00360
uniprot id: H2AXG9
names: Similarity
messages: Belongs to the PGA52 family.

1071382:KAFR 0F03100
gene id: 1071382:KAFR_0F03100
uniprot id: H2AX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

1071382:KAFR 0H02940
gene id: 1071382:KAFR_0H02940
uniprot id: H2AZE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0L00330
gene id: 1071382:KAFR_0L00330
uniprot id: H2B1Z0
names: Similarity
messages: Belongs to the MYBBP1A family.

1071382:KAFR 0A05020
gene id: 1071382:KAFR_0A05020
uniprot id: H2ANI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E01520
gene id: 1071382:KAFR_0E01520
uniprot id: H2AVA6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071382:KAFR 0F00380
gene id: 1071382:KAFR_0F00380
uniprot id: H2AW85
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0K02010
gene id: 1071382:KAFR_0K02010
uniprot id: H2B1Q5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1071382:KAFR 0J02970
gene id: 1071382:KAFR_0J02970
uniprot id: H2B161
names: Similarity
messages: Belongs to the hexokinase family.

1071382:KAFR 0B05890
gene id: 1071382:KAFR_0B05890
uniprot id: H2AR85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

1071382:KAFR 0J02070
gene id: 1071382:KAFR_0J02070
uniprot id: H2B0X1
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

1071382:KAFR 0B05070
gene id: 1071382:KAFR_0B05070
uniprot id: H2AR03
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1071382:KAFR 0C06120
gene id: 1071382:KAFR_0C06120
uniprot id: H2ATA4
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1071382:KAFR 0F00360
gene id: 1071382:KAFR_0F00360
uniprot id: H2AW83
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

1071382:KAFR 0D03460
gene id: 1071382:KAFR_0D03460
uniprot id: H2AUE4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1071382:KAFR 0J01320
gene id: 1071382:KAFR_0J01320
uniprot id: H2B0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071382:KAFR 0B01980
gene id: 1071382:KAFR_0B01980
uniprot id: H2AQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0L01900
gene id: 1071382:KAFR_0L01900
uniprot id: H2B2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
messages: telomere

1071382:KAFR 0I01610
gene id: 1071382:KAFR_0I01610
uniprot id: H2AZZ2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B00200
gene id: 1071382:KAFR_0B00200
uniprot id: H2APM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1071382:KAFR 0G02480
gene id: 1071382:KAFR_0G02480
uniprot id: H2AY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

1071382:KAFR 0B03320
gene id: 1071382:KAFR_0B03320
uniprot id: H2AQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

1071382:KAFR 0E00440
gene id: 1071382:KAFR_0E00440
uniprot id: H2AUZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

1071382:KAFR 0E01530
gene id: 1071382:KAFR_0E01530
uniprot id: H2AVA7
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071382:KAFR 0I02410
gene id: 1071382:KAFR_0I02410
uniprot id: H2B070
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

1071382:KAFR 0F02500
gene id: 1071382:KAFR_0F02500
uniprot id: H2AWU7
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071382:KAFR 0A04700
gene id: 1071382:KAFR_0A04700
uniprot id: H2ANF5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0C06300
gene id: 1071382:KAFR_0C06300
uniprot id: H2ATC6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A08290
gene id: 1071382:KAFR_0A08290
uniprot id: H2APG3
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071382:KAFR 0F02320
gene id: 1071382:KAFR_0F02320
uniprot id: H2AWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

1071382:KAFR 0I02920
gene id: 1071382:KAFR_0I02920
uniprot id: H2B0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

1071382:KAFR 0D03320
gene id: 1071382:KAFR_0D03320
uniprot id: H2AUD0
names: Function
names: Similarity
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.

1071382:KAFR 0C01630
gene id: 1071382:KAFR_0C01630
uniprot id: H2AS06
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0G03550
gene id: 1071382:KAFR_0G03550
uniprot id: H2AYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

1071382:KAFR 0C06110
gene id: 1071382:KAFR_0C06110
uniprot id: H2ATA3
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

1071382:KAFR 0E03370
gene id: 1071382:KAFR_0E03370
uniprot id: H2AVT9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C01860
gene id: 1071382:KAFR_0C01860
uniprot id: H2AS29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Yeast FIT2A/YFT2 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization). Involved in phospholipid biosynthesis.
messages: Membrane

1071382:KAFR 0E01840
gene id: 1071382:KAFR_0E01840
uniprot id: H2AVD8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0K01990
gene id: 1071382:KAFR_0K01990
uniprot id: H2B1Q3
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1071382:KAFR 0E03410
gene id: 1071382:KAFR_0E03410
uniprot id: H2AVU3
names: Similarity
messages: Belongs to the PIAS family.

1071382:KAFR 0B02070
gene id: 1071382:KAFR_0B02070
uniprot id: H2AQ55
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0E02050
gene id: 1071382:KAFR_0E02050
uniprot id: H2AVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

1071382:KAFR 0I00770
gene id: 1071382:KAFR_0I00770
uniprot id: H2AZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1071382:KAFR 0B02890
gene id: 1071382:KAFR_0B02890
uniprot id: H2AQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

1071382:KAFR 0G01060
gene id: 1071382:KAFR_0G01060
uniprot id: H2AXN9
names: Similarity
messages: Belongs to the MIX23 family.

1071382:KAFR 0I01850
gene id: 1071382:KAFR_0I01850
uniprot id: H2B015
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

1071382:KAFR 0I00330
gene id: 1071382:KAFR_0I00330
uniprot id: H2AZL4
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

1071382:KAFR 0H02980
gene id: 1071382:KAFR_0H02980
uniprot id: H2AZF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1071382:KAFR 0H02210
gene id: 1071382:KAFR_0H02210
uniprot id: H2AZ74
names: Similarity
messages: Belongs to the SLX4 family.

1071382:KAFR 0A01130
gene id: 1071382:KAFR_0A01130
uniprot id: H2AMF2
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0C01790
gene id: 1071382:KAFR_0C01790
uniprot id: H2AS22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

1071382:KAFR 0J00440
gene id: 1071382:KAFR_0J00440
uniprot id: H2B0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

1071382:KAFR 0C03590
gene id: 1071382:KAFR_0C03590
uniprot id: H2ASK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0F02030
gene id: 1071382:KAFR_0F02030
uniprot id: H2AWQ0
names: Similarity
messages: Belongs to the NDK family.

1071382:KAFR 0A03930
gene id: 1071382:KAFR_0A03930
uniprot id: H2AN78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

1071382:KAFR 0B04220
gene id: 1071382:KAFR_0B04220
uniprot id: H2AQR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0A03820
gene id: 1071382:KAFR_0A03820
uniprot id: H2AN67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Required for methionine synthesis and maintenance of intact mitochondrial DNA. Involved in telomere maintenance.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

1071382:KAFR 0B00990
gene id: 1071382:KAFR_0B00990
uniprot id: H2APU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

1071382:KAFR 0B06060
gene id: 1071382:KAFR_0B06060
uniprot id: H2ARA2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0D01960
gene id: 1071382:KAFR_0D01960
uniprot id: H2ATZ3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1071382:KAFR 0A01300
gene id: 1071382:KAFR_0A01300
uniprot id: H2AMG8
names: Similarity
messages: Belongs to the TCP11 family.

1071382:KAFR 0A08380
gene id: 1071382:KAFR_0A08380
uniprot id: H2APH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1071382:KAFR 0C03220
gene id: 1071382:KAFR_0C03220
uniprot id: H2ASG4
names: Similarity
messages: Belongs to the YIP1 family.

1071382:KAFR 0I02790
gene id: 1071382:KAFR_0I02790
uniprot id: H2B0A8
names: Similarity
messages: Belongs to the NAD kinase family.

1071382:KAFR 0H03190
gene id: 1071382:KAFR_0H03190
uniprot id: H2AZH3
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0L01560
gene id: 1071382:KAFR_0L01560
uniprot id: H2B2B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071382:KAFR 0G00550
gene id: 1071382:KAFR_0G00550
uniprot id: H2AXI8
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071382:KAFR 0I00970
gene id: 1071382:KAFR_0I00970
uniprot id: H2AZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

1071382:KAFR 0L01210
gene id: 1071382:KAFR_0L01210
uniprot id: H2B279
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0B04070
gene id: 1071382:KAFR_0B04070
uniprot id: H2AQQ3
names: Similarity
messages: Belongs to the thioredoxin family.

1071382:KAFR 0D03570
gene id: 1071382:KAFR_0D03570
uniprot id: H2AUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

1071382:KAFR 0D01990
gene id: 1071382:KAFR_0D01990
uniprot id: H2ATZ6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1071382:KAFR 0D00300
gene id: 1071382:KAFR_0D00300
uniprot id: H2ATH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

1071382:KAFR 0B04450
gene id: 1071382:KAFR_0B04450
uniprot id: H2AQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

1071382:KAFR 0B01930
gene id: 1071382:KAFR_0B01930
uniprot id: H2AQ41
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

1071382:KAFR 0G02950
gene id: 1071382:KAFR_0G02950
uniprot id: H2AY77
names: Function
names: Similarity
messages: Belongs to the RRT5 family.
messages: May be involved in the modulation of rDNA transcription.

1071382:KAFR 0G01450
gene id: 1071382:KAFR_0G01450
uniprot id: H2AXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

1071382:KAFR 0D05040
gene id: 1071382:KAFR_0D05040
uniprot id: H2AUV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

1071382:KAFR 0F03220
gene id: 1071382:KAFR_0F03220
uniprot id: H2AX18
names: Similarity
messages: Belongs to the R-transferase family.

1071382:KAFR 0H03160
gene id: 1071382:KAFR_0H03160
uniprot id: H2AZH0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1071382:KAFR 0G02260
gene id: 1071382:KAFR_0G02260
uniprot id: H2AY10
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1071382:KAFR 0G03310
gene id: 1071382:KAFR_0G03310
uniprot id: H2AYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

1071382:KAFR 0A06480
gene id: 1071382:KAFR_0A06480
uniprot id: H2ANY3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

1071382:KAFR 0B00220
gene id: 1071382:KAFR_0B00220
uniprot id: H2APM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0J01660
gene id: 1071382:KAFR_0J01660
uniprot id: H2B0T1
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

1071382:KAFR 0K02590
gene id: 1071382:KAFR_0K02590
uniprot id: H2B1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A08360
gene id: 1071382:KAFR_0A08360
uniprot id: H2APH0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1071382:KAFR 0G01310
gene id: 1071382:KAFR_0G01310
uniprot id: H2AXR5
names: Similarity
messages: Belongs to the VPS72/YL1 family.

1071382:KAFR 0B01880
gene id: 1071382:KAFR_0B01880
uniprot id: H2AQ37
names: Similarity
messages: Belongs to the SNF8 family.

1071382:KAFR 0B02190
gene id: 1071382:KAFR_0B02190
uniprot id: H2AQ67
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0A06840
gene id: 1071382:KAFR_0A06840
uniprot id: H2AP19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0G02270
gene id: 1071382:KAFR_0G02270
uniprot id: H2AY11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

1071382:KAFR 0C01950
gene id: 1071382:KAFR_0C01950
uniprot id: H2AS38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

1071382:KAFR 0D03360
gene id: 1071382:KAFR_0D03360
uniprot id: H2AUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Endosome membrane

1071382:KAFR 0K01740
gene id: 1071382:KAFR_0K01740
uniprot id: H2B1M8
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1071382:KAFR 0L02010
gene id: 1071382:KAFR_0L02010
uniprot id: H2B2G2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0E04000
gene id: 1071382:KAFR_0E04000
uniprot id: H2AW01
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

1071382:KAFR 0C05020
gene id: 1071382:KAFR_0C05020
uniprot id: H2ASZ3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1071382:KAFR 0C01170
gene id: 1071382:KAFR_0C01170
uniprot id: H2ARW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

1071382:KAFR 0C01010
gene id: 1071382:KAFR_0C01010
uniprot id: H2ARU6
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071382:KAFR 0D01630
gene id: 1071382:KAFR_0D01630
uniprot id: H2ATV9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B04430
gene id: 1071382:KAFR_0B04430
uniprot id: H2AQT9
names: Similarity
messages: Belongs to the enolase family.

1071382:KAFR 0A02720
gene id: 1071382:KAFR_0A02720
uniprot id: H2AMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1071382:KAFR 0E03250
gene id: 1071382:KAFR_0E03250
uniprot id: H2AVS7
names: Similarity
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Homodimer.

1071382:KAFR 0C03360
gene id: 1071382:KAFR_0C03360
uniprot id: H2ASH8
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

1071382:KAFR 0C01510
gene id: 1071382:KAFR_0C01510
uniprot id: H2ARZ4
names: Similarity
messages: Belongs to the lysophospholipase family.

1071382:KAFR 0J02560
gene id: 1071382:KAFR_0J02560
uniprot id: H2B120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

1071382:KAFR 0C05960
gene id: 1071382:KAFR_0C05960
uniprot id: H2AT87
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0H00160
gene id: 1071382:KAFR_0H00160
uniprot id: H2AYL9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1071382:KAFR 0H01920
gene id: 1071382:KAFR_0H01920
uniprot id: H2AZ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1071382:KAFR 0I02340
gene id: 1071382:KAFR_0I02340
uniprot id: H2B063
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1071382:KAFR 0F01740
gene id: 1071382:KAFR_0F01740
uniprot id: H2AWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

1071382:KAFR 0J01640
gene id: 1071382:KAFR_0J01640
uniprot id: H2B0S9
names: Similarity
messages: Belongs to the SUN family.

1071382:KAFR 0D00400
gene id: 1071382:KAFR_0D00400
uniprot id: H2ATI7
names: Similarity
messages: Belongs to the RRP7 family.

1071382:KAFR 0F04380
gene id: 1071382:KAFR_0F04380
uniprot id: H2AXD3
names: Similarity
messages: Belongs to the peptidase M24B family.

1071382:KAFR 0D01080
gene id: 1071382:KAFR_0D01080
uniprot id: H2ATQ4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D04610
gene id: 1071382:KAFR_0D04610
uniprot id: H2AUQ9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0F01780
gene id: 1071382:KAFR_0F01780
uniprot id: H2AWM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A05180
gene id: 1071382:KAFR_0A05180
uniprot id: H2ANK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

1071382:KAFR 0J02400
gene id: 1071382:KAFR_0J02400
uniprot id: H2B104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0J00660
gene id: 1071382:KAFR_0J00660
uniprot id: H2B0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1071382:KAFR 0B05830
gene id: 1071382:KAFR_0B05830
uniprot id: H2AR79
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

1071382:KAFR 0I01160
gene id: 1071382:KAFR_0I01160
uniprot id: H2AZU7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

1071382:KAFR 0K02400
gene id: 1071382:KAFR_0K02400
uniprot id: H2B1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0C03100
gene id: 1071382:KAFR_0C03100
uniprot id: H2ASF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

1071382:KAFR 0G01580
gene id: 1071382:KAFR_0G01580
uniprot id: H2AXU2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01490
gene id: 1071382:KAFR_0A01490
uniprot id: H2AMI7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1071382:KAFR 0A05030
gene id: 1071382:KAFR_0A05030
uniprot id: H2ANI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

1071382:KAFR 0K00770
gene id: 1071382:KAFR_0K00770
uniprot id: H2B1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

1071382:KAFR 0D03790
gene id: 1071382:KAFR_0D03790
uniprot id: H2AUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

1071382:KAFR 0D01540
gene id: 1071382:KAFR_0D01540
uniprot id: H2ATV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

1071382:KAFR 0C03080
gene id: 1071382:KAFR_0C03080
uniprot id: H2ASF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

1071382:KAFR 0E01790
gene id: 1071382:KAFR_0E01790
uniprot id: H2AVD3
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

1071382:KAFR 0G02140
gene id: 1071382:KAFR_0G02140
uniprot id: H2AXZ8
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071382:KAFR 0K02140
gene id: 1071382:KAFR_0K02140
uniprot id: H2B1R8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0E02030
gene id: 1071382:KAFR_0E02030
uniprot id: H2AVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0H01350
gene id: 1071382:KAFR_0H01350
uniprot id: H2AYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

1071382:KAFR 0B06970
gene id: 1071382:KAFR_0B06970
uniprot id: H2ARJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071382:KAFR 0A05060
gene id: 1071382:KAFR_0A05060
uniprot id: H2ANJ2
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0C02900
gene id: 1071382:KAFR_0C02900
uniprot id: H2ASD3
names: Similarity
messages: Belongs to the GCN1 family.

1071382:KAFR 0B05430
gene id: 1071382:KAFR_0B05430
uniprot id: H2AR38
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1071382:KAFR 0J02110
gene id: 1071382:KAFR_0J02110
uniprot id: H2B0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

1071382:KAFR 0D02990
gene id: 1071382:KAFR_0D02990
uniprot id: H2AU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

1071382:KAFR 0A00970
gene id: 1071382:KAFR_0A00970
uniprot id: H2AMD5
names: Similarity
messages: Belongs to the SH3YL1 family.

1071382:KAFR 0A05490
gene id: 1071382:KAFR_0A05490
uniprot id: H2ANN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1071382:KAFR 0I01740
gene id: 1071382:KAFR_0I01740
uniprot id: H2B005
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1071382:KAFR 0G02460
gene id: 1071382:KAFR_0G02460
uniprot id: H2AY29
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B02310
gene id: 1071382:KAFR_0B02310
uniprot id: H2AQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

1071382:KAFR 0B02400
gene id: 1071382:KAFR_0B02400
uniprot id: H2AQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1071382:KAFR 0L01800
gene id: 1071382:KAFR_0L01800
uniprot id: H2B2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

1071382:KAFR 0A06970
gene id: 1071382:KAFR_0A06970
uniprot id: H2AP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

1071382:KAFR 0J02420
gene id: 1071382:KAFR_0J02420
uniprot id: H2B106
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0J02890
gene id: 1071382:KAFR_0J02890
uniprot id: H2B153
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

1071382:KAFR 0A04130
gene id: 1071382:KAFR_0A04130
uniprot id: H2AN98
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

1071382:KAFR 0G03320
gene id: 1071382:KAFR_0G03320
uniprot id: H2AYB4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1071382:KAFR 0A04980
gene id: 1071382:KAFR_0A04980
uniprot id: H2ANI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071382:KAFR 0G02610
gene id: 1071382:KAFR_0G02610
uniprot id: H2AY43
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0C06180
gene id: 1071382:KAFR_0C06180
uniprot id: H2ATB0
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1071382:KAFR 0D01520
gene id: 1071382:KAFR_0D01520
uniprot id: H2ATU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1071382:KAFR 0J02820
gene id: 1071382:KAFR_0J02820
uniprot id: H2B146
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

1071382:KAFR 0C05300
gene id: 1071382:KAFR_0C05300
uniprot id: H2AT21
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071382:KAFR 0D00630
gene id: 1071382:KAFR_0D00630
uniprot id: H2ATL0
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

1071382:KAFR 0G01970
gene id: 1071382:KAFR_0G01970
uniprot id: H2AXY1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1071382:KAFR 0F03270
gene id: 1071382:KAFR_0F03270
uniprot id: H2AX23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

1071382:KAFR 0F01050
gene id: 1071382:KAFR_0F01050
uniprot id: H2AWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

1071382:KAFR 0C04790
gene id: 1071382:KAFR_0C04790
uniprot id: H2ASX0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071382:KAFR 0D02670
gene id: 1071382:KAFR_0D02670
uniprot id: H2AU65
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1071382:KAFR 0L02060
gene id: 1071382:KAFR_0L02060
uniprot id: H2B2G7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

1071382:KAFR 0G01430
gene id: 1071382:KAFR_0G01430
uniprot id: H2AXS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

1071382:KAFR 0H02520
gene id: 1071382:KAFR_0H02520
uniprot id: H2AZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0I01600
gene id: 1071382:KAFR_0I01600
uniprot id: H2AZZ1
names: Similarity
messages: Belongs to the EIS1 family.

1071382:KAFR 0C05400
gene id: 1071382:KAFR_0C05400
uniprot id: H2AT31
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0K02460
gene id: 1071382:KAFR_0K02460
uniprot id: H2B1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1071382:KAFR 0A01050
gene id: 1071382:KAFR_0A01050
uniprot id: H2AME4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0I00760
gene id: 1071382:KAFR_0I00760
uniprot id: H2AZQ7
names: Similarity
messages: Belongs to the SEN54 family.

1071382:KAFR 0E02830
gene id: 1071382:KAFR_0E02830
uniprot id: H2AVN5
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

1071382:KAFR 0C05380
gene id: 1071382:KAFR_0C05380
uniprot id: H2AT29
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071382:KAFR 0F04390
gene id: 1071382:KAFR_0F04390
uniprot id: H2AXD4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01980
gene id: 1071382:KAFR_0A01980
uniprot id: H2AMN6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E03300
gene id: 1071382:KAFR_0E03300
uniprot id: H2AVT2
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1071382:KAFR 0B01950
gene id: 1071382:KAFR_0B01950
uniprot id: H2AQ43
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E04480
gene id: 1071382:KAFR_0E04480
uniprot id: H2AW48
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0F00125
gene id: 1071382:KAFR_0F00125
uniprot id: H2AW57
names: Similarity
messages: Belongs to the arginase family.

1071382:KAFR 0E00350
gene id: 1071382:KAFR_0E00350
uniprot id: H2AUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

1071382:KAFR 0A08110
gene id: 1071382:KAFR_0A08110
uniprot id: H2APE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0F03430
gene id: 1071382:KAFR_0F03430
uniprot id: H2AX39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0C01070
gene id: 1071382:KAFR_0C01070
uniprot id: H2ARV2
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

1071382:KAFR 0C05680
gene id: 1071382:KAFR_0C05680
uniprot id: H2AT59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

1071382:KAFR 0H00110
gene id: 1071382:KAFR_0H00110
uniprot id: H2AYL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1071382:KAFR 0F03040
gene id: 1071382:KAFR_0F03040
uniprot id: H2AX00
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0F04040
gene id: 1071382:KAFR_0F04040
uniprot id: H2AX99
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

1071382:KAFR 0A02150
gene id: 1071382:KAFR_0A02150
uniprot id: H2AMQ3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0H03770
gene id: 1071382:KAFR_0H03770
uniprot id: H2AYL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0H02300
gene id: 1071382:KAFR_0H02300
uniprot id: H2AZ83
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0D00460
gene id: 1071382:KAFR_0D00460
uniprot id: H2ATJ3
names: Similarity
messages: Belongs to the UFD1 family.

1071382:KAFR 0H02610
gene id: 1071382:KAFR_0H02610
uniprot id: H2AZB4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1071382:KAFR 0A02480
gene id: 1071382:KAFR_0A02480
uniprot id: H2AMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071382:KAFR 0I02650
gene id: 1071382:KAFR_0I02650
uniprot id: H2B094
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

1071382:KAFR 0C04400
gene id: 1071382:KAFR_0C04400
uniprot id: H2AST0
names: Similarity
messages: Belongs to the SH3YL1 family.

1071382:KAFR 0B02060
gene id: 1071382:KAFR_0B02060
uniprot id: H2AQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

1071382:KAFR 0D03670
gene id: 1071382:KAFR_0D03670
uniprot id: H2AUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071382:KAFR 0D04520
gene id: 1071382:KAFR_0D04520
uniprot id: H2AUQ0
names: Similarity
messages: Belongs to the PIH1 family.

1071382:KAFR 0A02680
gene id: 1071382:KAFR_0A02680
uniprot id: H2AMV4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0E03620
gene id: 1071382:KAFR_0E03620
uniprot id: H2AVW3
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

1071382:KAFR 0B01700
gene id: 1071382:KAFR_0B01700
uniprot id: H2AQ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1071382:KAFR 0G00280
gene id: 1071382:KAFR_0G00280
uniprot id: H2AXG1
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071382:KAFR 0A01700
gene id: 1071382:KAFR_0A01700
uniprot id: H2AMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

1071382:KAFR 0A02530
gene id: 1071382:KAFR_0A02530
uniprot id: H2AMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

1071382:KAFR 0E00390
gene id: 1071382:KAFR_0E00390
uniprot id: H2AUZ3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L02120
gene id: 1071382:KAFR_0L02120
uniprot id: H2B2H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

1071382:KAFR 0E00500
gene id: 1071382:KAFR_0E00500
uniprot id: H2AV04
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1071382:KAFR 0B06650
gene id: 1071382:KAFR_0B06650
uniprot id: H2ARG2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071382:KAFR 0A03450
gene id: 1071382:KAFR_0A03450
uniprot id: H2AN30
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0G01230
gene id: 1071382:KAFR_0G01230
uniprot id: H2AXQ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.

1071382:KAFR 0K01950
gene id: 1071382:KAFR_0K01950
uniprot id: H2B1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1071382:KAFR 0G02650
gene id: 1071382:KAFR_0G02650
uniprot id: H2AY46
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01390
gene id: 1071382:KAFR_0A01390
uniprot id: H2AMH7
names: Similarity
messages: Belongs to the SAPS family.

1071382:KAFR 0B00900
gene id: 1071382:KAFR_0B00900
uniprot id: H2APT8
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

1071382:KAFR 0B06230
gene id: 1071382:KAFR_0B06230
uniprot id: H2ARC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0B04490
gene id: 1071382:KAFR_0B04490
uniprot id: H2AQU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1071382:KAFR 0I02720
gene id: 1071382:KAFR_0I02720
uniprot id: H2B0A1
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0H01420
gene id: 1071382:KAFR_0H01420
uniprot id: H2AYZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

1071382:KAFR 0C00740
gene id: 1071382:KAFR_0C00740
uniprot id: H2ARR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

1071382:KAFR 0G03780
gene id: 1071382:KAFR_0G03780
uniprot id: H2AYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1071382:KAFR 0D04350
gene id: 1071382:KAFR_0D04350
uniprot id: H2AUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

1071382:KAFR 0I02190
gene id: 1071382:KAFR_0I02190
uniprot id: H2B048
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071382:KAFR 0E03700
gene id: 1071382:KAFR_0E03700
uniprot id: H2AVX1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071382:KAFR 0D02970
gene id: 1071382:KAFR_0D02970
uniprot id: H2AU95
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1071382:KAFR 0F01480
gene id: 1071382:KAFR_0F01480
uniprot id: H2AWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071382:KAFR 0K01560
gene id: 1071382:KAFR_0K01560
uniprot id: H2B1L0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0E04240
gene id: 1071382:KAFR_0E04240
uniprot id: H2AW25
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

1071382:KAFR 0A01320
gene id: 1071382:KAFR_0A01320
uniprot id: H2AMH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071382:KAFR 0K01810
gene id: 1071382:KAFR_0K01810
uniprot id: H2B1N5
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0G02410
gene id: 1071382:KAFR_0G02410
uniprot id: H2AY25
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

1071382:KAFR 0C05950
gene id: 1071382:KAFR_0C05950
uniprot id: H2AT86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

1071382:KAFR 0A07330
gene id: 1071382:KAFR_0A07330
uniprot id: H2AP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A03660
gene id: 1071382:KAFR_0A03660
uniprot id: H2AN51
names: Similarity
messages: Belongs to the peptidase M20A family.

1071382:KAFR 0L00830
gene id: 1071382:KAFR_0L00830
uniprot id: H2B241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0B03400
gene id: 1071382:KAFR_0B03400
uniprot id: H2AQI7
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0D04740
gene id: 1071382:KAFR_0D04740
uniprot id: H2AUS1
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0B01400
gene id: 1071382:KAFR_0B01400
uniprot id: H2APY9
names: Function
names: Similarity
messages: Belongs to the RGI1 family.
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

1071382:KAFR 0L00410
gene id: 1071382:KAFR_0L00410
uniprot id: H2B1Z8
names: Similarity
messages: Belongs to the SGT family.

1071382:KAFR 0H02430
gene id: 1071382:KAFR_0H02430
uniprot id: H2AZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

1071382:KAFR 0H01560
gene id: 1071382:KAFR_0H01560
uniprot id: H2AZ10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1071382:KAFR 0F02780
gene id: 1071382:KAFR_0F02780
uniprot id: H2AWX5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1071382:KAFR 0F01660
gene id: 1071382:KAFR_0F01660
uniprot id: H2AWL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

1071382:KAFR 0C02360
gene id: 1071382:KAFR_0C02360
uniprot id: H2AS79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

1071382:KAFR 0D04320
gene id: 1071382:KAFR_0D04320
uniprot id: H2AUN0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0F01320
gene id: 1071382:KAFR_0F01320
uniprot id: H2AWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1071382:KAFR 0B03590
gene id: 1071382:KAFR_0B03590
uniprot id: H2AQK6
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

1071382:KAFR 0B03870
gene id: 1071382:KAFR_0B03870
uniprot id: H2AQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A00380
gene id: 1071382:KAFR_0A00380
uniprot id: H2AM76
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0F00800
gene id: 1071382:KAFR_0F00800
uniprot id: H2AWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

1071382:KAFR 0E02630
gene id: 1071382:KAFR_0E02630
uniprot id: H2AVL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

1071382:KAFR 0B04060
gene id: 1071382:KAFR_0B04060
uniprot id: H2AQQ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1071382:KAFR 0F01260
gene id: 1071382:KAFR_0F01260
uniprot id: H2AWH2
names: Similarity
messages: Belongs to the SELO family.

1071382:KAFR 0L01490
gene id: 1071382:KAFR_0L01490
uniprot id: H2B2A9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071382:KAFR 0J00210
gene id: 1071382:KAFR_0J00210
uniprot id: H2B0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0C02810
gene id: 1071382:KAFR_0C02810
uniprot id: H2ASC4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1071382:KAFR 0H02670
gene id: 1071382:KAFR_0H02670
uniprot id: H2AZC0
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

1071382:KAFR 0A07780
gene id: 1071382:KAFR_0A07780
uniprot id: H2APB2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0D01140
gene id: 1071382:KAFR_0D01140
uniprot id: H2ATR0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1071382:KAFR 0K00330
gene id: 1071382:KAFR_0K00330
uniprot id: H2B188
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0H03720
gene id: 1071382:KAFR_0H03720
uniprot id: H2AYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE28 family.
messages: Involved in kinetochore-microtubule binding and the spindle assembly checkpoint.
messages: Nucleus membrane
messages: kinetochore
messages: spindle pole body

1071382:KAFR 0E00280
gene id: 1071382:KAFR_0E00280
uniprot id: H2AUY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

1071382:KAFR 0K01580
gene id: 1071382:KAFR_0K01580
uniprot id: H2B1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D03350
gene id: 1071382:KAFR_0D03350
uniprot id: H2AUD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

1071382:KAFR 0J02210
gene id: 1071382:KAFR_0J02210
uniprot id: H2B0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

1071382:KAFR 0E02430
gene id: 1071382:KAFR_0E02430
uniprot id: H2AVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

1071382:KAFR 0L01670
gene id: 1071382:KAFR_0L01670
uniprot id: H2B2C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

1071382:KAFR 0B02700
gene id: 1071382:KAFR_0B02700
uniprot id: H2AQB7
names: Function
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

1071382:KAFR 0C02930
gene id: 1071382:KAFR_0C02930
uniprot id: H2ASD6
names: Similarity
messages: Belongs to the MT-A70-like family.

1071382:KAFR 0C06470
gene id: 1071382:KAFR_0C06470
uniprot id: H2ATE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071382:KAFR 0C05210
gene id: 1071382:KAFR_0C05210
uniprot id: H2AT12
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J02350
gene id: 1071382:KAFR_0J02350
uniprot id: H2B0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

1071382:KAFR 0E03890
gene id: 1071382:KAFR_0E03890
uniprot id: H2AVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0J00760
gene id: 1071382:KAFR_0J00760
uniprot id: H2B0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0E01870
gene id: 1071382:KAFR_0E01870
uniprot id: H2AVE1
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1071382:KAFR 0D01810
gene id: 1071382:KAFR_0D01810
uniprot id: H2ATX8
names: Similarity
messages: Belongs to the HGH1 family.

1071382:KAFR 0K00550
gene id: 1071382:KAFR_0K00550
uniprot id: H2B1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

1071382:KAFR 0G00540
gene id: 1071382:KAFR_0G00540
uniprot id: H2AXI7
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

1071382:KAFR 0G01040
gene id: 1071382:KAFR_0G01040
uniprot id: H2AXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

1071382:KAFR 0H02280
gene id: 1071382:KAFR_0H02280
uniprot id: H2AZ81
names: Similarity
messages: Belongs to the cullin family.

1071382:KAFR 0A05330
gene id: 1071382:KAFR_0A05330
uniprot id: H2ANL8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1071382:KAFR 0C06480
gene id: 1071382:KAFR_0C06480
uniprot id: H2ATE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071382:KAFR 0F01170
gene id: 1071382:KAFR_0F01170
uniprot id: H2AWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071382:KAFR 0E02190
gene id: 1071382:KAFR_0E02190
uniprot id: H2AVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0J02750
gene id: 1071382:KAFR_0J02750
uniprot id: H2B139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071382:KAFR 0B00850
gene id: 1071382:KAFR_0B00850
uniprot id: H2APT3
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

1071382:KAFR 0B02300
gene id: 1071382:KAFR_0B02300
uniprot id: H2AQ78
names: Similarity
messages: Belongs to the DDI1 family.

1071382:KAFR 0D03580
gene id: 1071382:KAFR_0D03580
uniprot id: H2AUF6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I00820
gene id: 1071382:KAFR_0I00820
uniprot id: H2AZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0B04670
gene id: 1071382:KAFR_0B04670
uniprot id: H2AQW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

1071382:KAFR 0B00570
gene id: 1071382:KAFR_0B00570
uniprot id: H2APQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

1071382:KAFR 0B05000
gene id: 1071382:KAFR_0B05000
uniprot id: H2AQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071382:KAFR 0H01230
gene id: 1071382:KAFR_0H01230
uniprot id: H2AYX7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0J02370
gene id: 1071382:KAFR_0J02370
uniprot id: H2B101
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

1071382:KAFR 0G01500
gene id: 1071382:KAFR_0G01500
uniprot id: H2AXT4
names: Similarity
messages: Belongs to the SUN family.

1071382:KAFR 0A07320
gene id: 1071382:KAFR_0A07320
uniprot id: H2AP66
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0C01020
gene id: 1071382:KAFR_0C01020
uniprot id: H2ARU7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071382:KAFR 0E01880
gene id: 1071382:KAFR_0E01880
uniprot id: H2AVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0C06150
gene id: 1071382:KAFR_0C06150
uniprot id: H2ATA7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

1071382:KAFR 0B00180
gene id: 1071382:KAFR_0B00180
uniprot id: H2APL8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D01430
gene id: 1071382:KAFR_0D01430
uniprot id: H2ATT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071382:KAFR 0C01750
gene id: 1071382:KAFR_0C01750
uniprot id: H2AS18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071382:KAFR 0K01430
gene id: 1071382:KAFR_0K01430
uniprot id: H2B1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

1071382:KAFR 0I00580
gene id: 1071382:KAFR_0I00580
uniprot id: H2AZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

1071382:KAFR 0B06890
gene id: 1071382:KAFR_0B06890
uniprot id: H2ARI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Nucleus

1071382:KAFR 0C01840
gene id: 1071382:KAFR_0C01840
uniprot id: H2AS27
names: Similarity
messages: Belongs to the NOP10 family.

1071382:KAFR 0K02530
gene id: 1071382:KAFR_0K02530
uniprot id: H2B1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum

1071382:KAFR 0K01660
gene id: 1071382:KAFR_0K01660
uniprot id: H2B1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0G01870
gene id: 1071382:KAFR_0G01870
uniprot id: H2AXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

1071382:KAFR 0K00850
gene id: 1071382:KAFR_0K00850
uniprot id: H2B1E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A06760
gene id: 1071382:KAFR_0A06760
uniprot id: H2AP11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

1071382:KAFR 0A00430
gene id: 1071382:KAFR_0A00430
uniprot id: H2AM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

1071382:KAFR 0F01930
gene id: 1071382:KAFR_0F01930
uniprot id: H2AWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F04060
gene id: 1071382:KAFR_0F04060
uniprot id: H2AXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1071382:KAFR 0D04120
gene id: 1071382:KAFR_0D04120
uniprot id: H2AUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0D00310
gene id: 1071382:KAFR_0D00310
uniprot id: H2ATH8
names: Similarity
messages: Belongs to the hexokinase family.

1071382:KAFR 0K02390
gene id: 1071382:KAFR_0K02390
uniprot id: H2B1U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0C04220
gene id: 1071382:KAFR_0C04220
uniprot id: H2ASR3
names: Similarity
messages: Belongs to the SDHAF4 family.

1071382:KAFR 0B04050
gene id: 1071382:KAFR_0B04050
uniprot id: H2AQQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1071382:KAFR 0A06660
gene id: 1071382:KAFR_0A06660
uniprot id: H2AP01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

1071382:KAFR 0L00500
gene id: 1071382:KAFR_0L00500
uniprot id: H2B207
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

1071382:KAFR 0L01780
gene id: 1071382:KAFR_0L01780
uniprot id: H2B1N8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

1071382:KAFR 0A01810
gene id: 1071382:KAFR_0A01810
uniprot id: H2AML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0J00750
gene id: 1071382:KAFR_0J00750
uniprot id: H2B0J3
names: Similarity
messages: Belongs to the END3 family.

1071382:KAFR 0G00890
gene id: 1071382:KAFR_0G00890
uniprot id: H2AXM2
names: Similarity
messages: Belongs to the peptidase C12 family.

1071382:KAFR 0B01100
gene id: 1071382:KAFR_0B01100
uniprot id: H2APV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1071382:KAFR 0C03540
gene id: 1071382:KAFR_0C03540
uniprot id: H2ASJ6
names: Similarity
messages: Belongs to the TMCO4 family.

1071382:KAFR 0L02100
gene id: 1071382:KAFR_0L02100
uniprot id: H2B2H1
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

1071382:KAFR 0K01730
gene id: 1071382:KAFR_0K01730
uniprot id: H2B1M7
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0J01300
gene id: 1071382:KAFR_0J01300
uniprot id: H2B0P7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0C00700
gene id: 1071382:KAFR_0C00700
uniprot id: H2B0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0J01820
gene id: 1071382:KAFR_0J01820
uniprot id: H2B0U6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B05710
gene id: 1071382:KAFR_0B05710
uniprot id: H2AR67
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0D02510
gene id: 1071382:KAFR_0D02510
uniprot id: H2AU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

1071382:KAFR 0C05450
gene id: 1071382:KAFR_0C05450
uniprot id: H2AT36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

1071382:KAFR 0D00180
gene id: 1071382:KAFR_0D00180
uniprot id: H2ATG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1071382:KAFR 0J01720
gene id: 1071382:KAFR_0J01720
uniprot id: H2B0T6
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0H03210
gene id: 1071382:KAFR_0H03210
uniprot id: H2AZH5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1071382:KAFR 0J01880
gene id: 1071382:KAFR_0J01880
uniprot id: H2B0V2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G03360
gene id: 1071382:KAFR_0G03360
uniprot id: H2AYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

1071382:KAFR 0D04680
gene id: 1071382:KAFR_0D04680
uniprot id: H2AUR6
names: Similarity
messages: Belongs to the OSBP family.

1071382:KAFR 0F04170
gene id: 1071382:KAFR_0F04170
uniprot id: H2AXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071382:KAFR 0A04570
gene id: 1071382:KAFR_0A04570
uniprot id: H2ANE2
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1071382:KAFR 0A02170
gene id: 1071382:KAFR_0A02170
uniprot id: H2AMQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1071382:KAFR 0D03710
gene id: 1071382:KAFR_0D03710
uniprot id: H2AUG9
names: Similarity
messages: Belongs to the SUI1 family.

1071382:KAFR 0D01950
gene id: 1071382:KAFR_0D01950
uniprot id: H2ATZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

1071382:KAFR 0B02240
gene id: 1071382:KAFR_0B02240
uniprot id: H2AQ72
names: Similarity
messages: Belongs to the Rab GDI family.

1071382:KAFR 0D02530
gene id: 1071382:KAFR_0D02530
uniprot id: H2AU50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

1071382:KAFR 0F00340
gene id: 1071382:KAFR_0F00340
uniprot id: H2AW81
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F02630
gene id: 1071382:KAFR_0F02630
uniprot id: H2AWW0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071382:KAFR 0F02250
gene id: 1071382:KAFR_0F02250
uniprot id: H2AWS2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C00770
gene id: 1071382:KAFR_0C00770
uniprot id: H2ARS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0F00820
gene id: 1071382:KAFR_0F00820
uniprot id: H2AWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D01640
gene id: 1071382:KAFR_0D01640
uniprot id: H2ATW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1071382:KAFR 0J02900
gene id: 1071382:KAFR_0J02900
uniprot id: H2B154
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1071382:KAFR 0H02410
gene id: 1071382:KAFR_0H02410
uniprot id: H2AZ94
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071382:KAFR 0C02660
gene id: 1071382:KAFR_0C02660
uniprot id: H2ASA9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I00400
gene id: 1071382:KAFR_0I00400
uniprot id: H2AZM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

1071382:KAFR 0H02100
gene id: 1071382:KAFR_0H02100
uniprot id: H2AZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1071382:KAFR 0F04080
gene id: 1071382:KAFR_0F04080
uniprot id: H2AXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0K01820
gene id: 1071382:KAFR_0K01820
uniprot id: H2B1N6
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071382:KAFR 0A07910
gene id: 1071382:KAFR_0A07910
uniprot id: H2APC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

1071382:KAFR 0L00550
gene id: 1071382:KAFR_0L00550
uniprot id: H2B212
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

1071382:KAFR 0B02740
gene id: 1071382:KAFR_0B02740
uniprot id: H2AQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
messages: Mitochondrion

1071382:KAFR 0H00790
gene id: 1071382:KAFR_0H00790
uniprot id: H2AYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

1071382:KAFR 0C04390
gene id: 1071382:KAFR_0C04390
uniprot id: H2ASS9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1071382:KAFR 0A08350
gene id: 1071382:KAFR_0A08350
uniprot id: H2APG9
names: Similarity
messages: Belongs to the MON2 family.

1071382:KAFR 0A03580
gene id: 1071382:KAFR_0A03580
uniprot id: H2AN43
names: Similarity
messages: Belongs to the BMT family.

1071382:KAFR 0E02460
gene id: 1071382:KAFR_0E02460
uniprot id: H2AVJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1071382:KAFR 0B04100
gene id: 1071382:KAFR_0B04100
uniprot id: H2AQQ6
names: Similarity
messages: Belongs to the ZPR1 family.

1071382:KAFR 0C02620
gene id: 1071382:KAFR_0C02620
uniprot id: H2ASA5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D05080
gene id: 1071382:KAFR_0D05080
uniprot id: H2AUV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

1071382:KAFR 0A05130
gene id: 1071382:KAFR_0A05130
uniprot id: H2ANJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0B03580
gene id: 1071382:KAFR_0B03580
uniprot id: H2AQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1071382:KAFR 0D01120
gene id: 1071382:KAFR_0D01120
uniprot id: H2ATQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

1071382:KAFR 0A07340
gene id: 1071382:KAFR_0A07340
uniprot id: H2AP68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

1071382:KAFR 0C06210
gene id: 1071382:KAFR_0C06210
uniprot id: H2ATB3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1071382:KAFR 0A05520
gene id: 1071382:KAFR_0A05520
uniprot id: H2ANN7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1071382:KAFR 0B00860
gene id: 1071382:KAFR_0B00860
uniprot id: H2APT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1071382:KAFR 0B03960
gene id: 1071382:KAFR_0B03960
uniprot id: H2AQP2
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

1071382:KAFR 0E00620
gene id: 1071382:KAFR_0E00620
uniprot id: H2AV16
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

1071382:KAFR 0L00570
gene id: 1071382:KAFR_0L00570
uniprot id: H2B214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

1071382:KAFR 0A04730
gene id: 1071382:KAFR_0A04730
uniprot id: H2ANF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

1071382:KAFR 0A06140
gene id: 1071382:KAFR_0A06140
uniprot id: H2ANU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071382:KAFR 0A03220
gene id: 1071382:KAFR_0A03220
uniprot id: H2AN07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1071382:KAFR 0G03220
gene id: 1071382:KAFR_0G03220
uniprot id: H2AYA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1071382:KAFR 0A07380
gene id: 1071382:KAFR_0A07380
uniprot id: H2AP72
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

1071382:KAFR 0A00640
gene id: 1071382:KAFR_0A00640
uniprot id: H2AMA2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of KAFR0A00640 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0G01210
gene id: 1071382:KAFR_0G01210
uniprot id: H2AXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0A05580
gene id: 1071382:KAFR_0A05580
uniprot id: H2ANP3
names: Similarity
messages: Belongs to the TSR2 family.

1071382:KAFR 0F00440
gene id: 1071382:KAFR_0F00440
uniprot id: H2AW91
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1071382:KAFR 0C01980
gene id: 1071382:KAFR_0C01980
uniprot id: H2AS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1071382:KAFR 0B03940
gene id: 1071382:KAFR_0B03940
uniprot id: H2AQP0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J02550
gene id: 1071382:KAFR_0J02550
uniprot id: H2B119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

1071382:KAFR 0K00250
gene id: 1071382:KAFR_0K00250
uniprot id: H2B180
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071382:KAFR 0D02270
gene id: 1071382:KAFR_0D02270
uniprot id: H2AU24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0B06620
gene id: 1071382:KAFR_0B06620
uniprot id: H2ARF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.
messages: The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.
messages: The capsid protein forms a homotrimer, from which the VLPs are assembled. The protease is a homodimer, whose active site consists of two apposed aspartic acid residues.

1071382:KAFR 0C02640
gene id: 1071382:KAFR_0C02640
uniprot id: H2ASA7
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1071382:KAFR 0D02390
gene id: 1071382:KAFR_0D02390
uniprot id: H2AU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

1071382:KAFR 0C01090
gene id: 1071382:KAFR_0C01090
uniprot id: H2ARV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1071382:KAFR 0G00180
gene id: 1071382:KAFR_0G00180
uniprot id: H2AXF1
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A05540
gene id: 1071382:KAFR_0A05540
uniprot id: H2ANN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0B01650
gene id: 1071382:KAFR_0B01650
uniprot id: H2AQ14
names: Similarity
messages: Belongs to the peptidase C48 family.

1071382:KAFR 0L01530
gene id: 1071382:KAFR_0L01530
uniprot id: H2B2B3
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

1071382:KAFR 0L00210
gene id: 1071382:KAFR_0L00210
uniprot id: H2B1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1071382:KAFR 0A04220
gene id: 1071382:KAFR_0A04220
uniprot id: H2ANA7
names: Similarity
messages: Belongs to the phosducin family.

1071382:KAFR 0B01380
gene id: 1071382:KAFR_0B01380
uniprot id: H2APY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

1071382:KAFR 0E03940
gene id: 1071382:KAFR_0E03940
uniprot id: H2AVZ5
names: Similarity
messages: Belongs to the peptidase A1 family.

1071382:KAFR 0J00480
gene id: 1071382:KAFR_0J00480
uniprot id: H2B0G6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F02600
gene id: 1071382:KAFR_0F02600
uniprot id: H2AWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3.
messages: Nucleus

1071382:KAFR 0H02830
gene id: 1071382:KAFR_0H02830
uniprot id: H2AZD6
names: Similarity
messages: Belongs to the beclin family.

1071382:KAFR 0F04140
gene id: 1071382:KAFR_0F04140
uniprot id: H2AXA9
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1071382:KAFR 0A04670
gene id: 1071382:KAFR_0A04670
uniprot id: H2ANF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

1071382:KAFR 0D00960
gene id: 1071382:KAFR_0D00960
uniprot id: H2ATP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

1071382:KAFR 0A01500
gene id: 1071382:KAFR_0A01500
uniprot id: H2AMI8
names: Similarity
messages: Belongs to the TRL1 family.

1071382:KAFR 0A04410
gene id: 1071382:KAFR_0A04410
uniprot id: H2ANC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1071382:KAFR 0A06370
gene id: 1071382:KAFR_0A06370
uniprot id: H2ANX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071382:KAFR 0E00710
gene id: 1071382:KAFR_0E00710
uniprot id: H2AV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0L01060
gene id: 1071382:KAFR_0L01060
uniprot id: H2B264
names: Similarity
messages: Belongs to the YOS1 family.

1071382:KAFR 0G02760
gene id: 1071382:KAFR_0G02760
uniprot id: H2AY57
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B03420
gene id: 1071382:KAFR_0B03420
uniprot id: H2AQI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

1071382:KAFR 0F03050
gene id: 1071382:KAFR_0F03050
uniprot id: H2AX01
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071382:KAFR 0G03240
gene id: 1071382:KAFR_0G03240
uniprot id: H2AYA6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0G02570
gene id: 1071382:KAFR_0G02570
uniprot id: H2AY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0B01810
gene id: 1071382:KAFR_0B01810
uniprot id: H2AQ30
names: Similarity
messages: Belongs to the peptidase M67A family.

1071382:KAFR 0A05420
gene id: 1071382:KAFR_0A05420
uniprot id: H2ANM7
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0G01600
gene id: 1071382:KAFR_0G01600
uniprot id: H2AXU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

1071382:KAFR 0C02710
gene id: 1071382:KAFR_0C02710
uniprot id: H2ASB4
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1071382:KAFR 0D00740
gene id: 1071382:KAFR_0D00740
uniprot id: H2ATM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0A05720
gene id: 1071382:KAFR_0A05720
uniprot id: H2ANQ7
names: Similarity
messages: Belongs to the SRR1 family.

1071382:KAFR 0J02190
gene id: 1071382:KAFR_0J02190
uniprot id: H2B0Y3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1071382:KAFR 0D03750
gene id: 1071382:KAFR_0D03750
uniprot id: H2AUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

1071382:KAFR 0K00960
gene id: 1071382:KAFR_0K00960
uniprot id: H2B1F2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0G03270
gene id: 1071382:KAFR_0G03270
uniprot id: H2AYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0H02190
gene id: 1071382:KAFR_0H02190
uniprot id: H2AZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

1071382:KAFR 0G02080
gene id: 1071382:KAFR_0G02080
uniprot id: H2AXZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

1071382:KAFR 0H01800
gene id: 1071382:KAFR_0H01800
uniprot id: H2AZ34
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B02420
gene id: 1071382:KAFR_0B02420
uniprot id: H2AQ90
names: Similarity
messages: Belongs to the MYG1 family.

1071382:KAFR 0F02640
gene id: 1071382:KAFR_0F02640
uniprot id: H2AWW1
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

1071382:KAFR 0E01810
gene id: 1071382:KAFR_0E01810
uniprot id: H2AVD5
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071382:KAFR 0B05520
gene id: 1071382:KAFR_0B05520
uniprot id: H2AR47
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1071382:KAFR 0D05130
gene id: 1071382:KAFR_0D05130
uniprot id: H2AUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0E02620
gene id: 1071382:KAFR_0E02620
uniprot id: H2AVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

1071382:KAFR 0I02610
gene id: 1071382:KAFR_0I02610
uniprot id: H2B090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071382:KAFR 0E03400
gene id: 1071382:KAFR_0E03400
uniprot id: H2AVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0L00360
gene id: 1071382:KAFR_0L00360
uniprot id: H2B1Z3
names: Similarity
messages: Belongs to the peptidase S8 family.

1071382:KAFR 0E03060
gene id: 1071382:KAFR_0E03060
uniprot id: H2AVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

1071382:KAFR 0I01210
gene id: 1071382:KAFR_0I01210
uniprot id: H2AZV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1071382:KAFR 0C03990
gene id: 1071382:KAFR_0C03990
uniprot id: H2ASP0
names: Similarity
messages: Belongs to the SURF6 family.

1071382:KAFR 0J01230
gene id: 1071382:KAFR_0J01230
uniprot id: H2B0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

1071382:KAFR 0E03090
gene id: 1071382:KAFR_0E03090
uniprot id: H2AVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1071382:KAFR 0B00440
gene id: 1071382:KAFR_0B00440
uniprot id: H2APP4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C01700
gene id: 1071382:KAFR_0C01700
uniprot id: H2AS13
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

1071382:KAFR 0C04630
gene id: 1071382:KAFR_0C04630
uniprot id: H2ASV4
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1071382:KAFR 0K01340
gene id: 1071382:KAFR_0K01340
uniprot id: H2B1I8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

1071382:KAFR 0F02420
gene id: 1071382:KAFR_0F02420
uniprot id: H2AWT9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1071382:KAFR 0B03150
gene id: 1071382:KAFR_0B03150
uniprot id: H2AQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

1071382:KAFR 0B03370
gene id: 1071382:KAFR_0B03370
uniprot id: H2AQI4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D00930
gene id: 1071382:KAFR_0D00930
uniprot id: H2ATP0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1071382:KAFR 0H01150
gene id: 1071382:KAFR_0H01150
uniprot id: H2AYW9
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

1071382:KAFR 0F02380
gene id: 1071382:KAFR_0F02380
uniprot id: H2AWT5
names: Similarity
messages: Belongs to the SCO1/2 family.

1071382:KAFR 0A01610
gene id: 1071382:KAFR_0A01610
uniprot id: H2AMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

1071382:KAFR 0H01340
gene id: 1071382:KAFR_0H01340
uniprot id: H2AYY8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1071382:KAFR 0K02000
gene id: 1071382:KAFR_0K02000
uniprot id: H2B1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Membrane
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

1071382:KAFR 0F03740
gene id: 1071382:KAFR_0F03740
uniprot id: H2ANX9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1071382:KAFR 0I00880
gene id: 1071382:KAFR_0I00880
uniprot id: H2AZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Nucleus

1071382:KAFR 0C06130
gene id: 1071382:KAFR_0C06130
uniprot id: H2ATA5
names: Similarity
messages: Belongs to the ETT1 family.

1071382:KAFR 0H03650
gene id: 1071382:KAFR_0H03650
uniprot id: H2AYJ8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1071382:KAFR 0G00300
gene id: 1071382:KAFR_0G00300
uniprot id: H2AXG3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L01130
gene id: 1071382:KAFR_0L01130
uniprot id: H2B271
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1071382:KAFR 0J02590
gene id: 1071382:KAFR_0J02590
uniprot id: H2B123
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071382:KAFR 0A01770
gene id: 1071382:KAFR_0A01770
uniprot id: H2AML5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

1071382:KAFR 0K01370
gene id: 1071382:KAFR_0K01370
uniprot id: H2B1J1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

1071382:KAFR 0A01360
gene id: 1071382:KAFR_0A01360
uniprot id: H2AMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

1071382:KAFR 0A00340
gene id: 1071382:KAFR_0A00340
uniprot id: H2AM72
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

1071382:KAFR 0D04560
gene id: 1071382:KAFR_0D04560
uniprot id: H2AUQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

1071382:KAFR 0B05310
gene id: 1071382:KAFR_0B05310
uniprot id: H2AR26
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G00860
gene id: 1071382:KAFR_0G00860
uniprot id: H2AXL9
names: Similarity
messages: Belongs to the VPS25 family.

1071382:KAFR 0B04880
gene id: 1071382:KAFR_0B04880
uniprot id: H2AQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071382:KAFR 0E03520
gene id: 1071382:KAFR_0E03520
uniprot id: H2AVV3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071382:KAFR 0G02230
gene id: 1071382:KAFR_0G02230
uniprot id: H2AY07
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071382:KAFR 0K00810
gene id: 1071382:KAFR_0K00810
uniprot id: H2B1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071382:KAFR 0F04210
gene id: 1071382:KAFR_0F04210
uniprot id: H2AXB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1071382:KAFR 0F03260
gene id: 1071382:KAFR_0F03260
uniprot id: H2AX22
names: Similarity
messages: Belongs to the PRP18 family.

1071382:KAFR 0E01160
gene id: 1071382:KAFR_0E01160
uniprot id: H2AV70
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0C02840
gene id: 1071382:KAFR_0C02840
uniprot id: H2ASC7
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071382:KAFR 0C05350
gene id: 1071382:KAFR_0C05350
uniprot id: H2AT26
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1071382:KAFR 0H03520
gene id: 1071382:KAFR_0H03520
uniprot id: H2AYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0G00880
gene id: 1071382:KAFR_0G00880
uniprot id: H2AXM1
names: Similarity
messages: Belongs to the phospholipid scramblase family.

1071382:KAFR 0E04250
gene id: 1071382:KAFR_0E04250
uniprot id: H2AW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B06040
gene id: 1071382:KAFR_0B06040
uniprot id: H2ARA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

1071382:KAFR 0I01720
gene id: 1071382:KAFR_0I01720
uniprot id: H2B003
names: Function
names: Similarity
messages: Belongs to the BLI1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.

1071382:KAFR 0A06350
gene id: 1071382:KAFR_0A06350
uniprot id: H2ANX0
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0F00590
gene id: 1071382:KAFR_0F00590
uniprot id: H2AWA6
names: Similarity
messages: Belongs to the actin family.

1071382:KAFR 0I02900
gene id: 1071382:KAFR_0I02900
uniprot id: H2B0B9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071382:KAFR 0B01170
gene id: 1071382:KAFR_0B01170
uniprot id: H2APW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

1071382:KAFR 0E00740
gene id: 1071382:KAFR_0E00740
uniprot id: H2AV28
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071382:KAFR 0L01110
gene id: 1071382:KAFR_0L01110
uniprot id: H2B269
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1071382:KAFR 0G03440
gene id: 1071382:KAFR_0G03440
uniprot id: H2AYC6
names: Function
names: Similarity
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

1071382:KAFR 0A03950
gene id: 1071382:KAFR_0A03950
uniprot id: H2AN80
names: Similarity
messages: Belongs to the TMA16 family.

1071382:KAFR 0D03560
gene id: 1071382:KAFR_0D03560
uniprot id: H2AUF4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071382:KAFR 0F00610
gene id: 1071382:KAFR_0F00610
uniprot id: H2AWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1071382:KAFR 0B01360
gene id: 1071382:KAFR_0B01360
uniprot id: H2APY5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1071382:KAFR 0C01360
gene id: 1071382:KAFR_0C01360
uniprot id: H2ARX9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K00360
gene id: 1071382:KAFR_0K00360
uniprot id: H2B191
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H03040
gene id: 1071382:KAFR_0H03040
uniprot id: H2AZF8
names: Similarity
messages: Belongs to the SWM2 family.

1071382:KAFR 0K01020
gene id: 1071382:KAFR_0K01020
uniprot id: H2B1F8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

1071382:KAFR 0C02070
gene id: 1071382:KAFR_0C02070
uniprot id: H2AS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1071382:KAFR 0C03240
gene id: 1071382:KAFR_0C03240
uniprot id: H2ASG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071382:KAFR 0C05430
gene id: 1071382:KAFR_0C05430
uniprot id: H2AT34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

1071382:KAFR 0G01110
gene id: 1071382:KAFR_0G01110
uniprot id: H2AXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

1071382:KAFR 0H01510
gene id: 1071382:KAFR_0H01510
uniprot id: H2AZ05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

1071382:KAFR 0E03440
gene id: 1071382:KAFR_0E03440
uniprot id: H2AVU6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C05540
gene id: 1071382:KAFR_0C05540
uniprot id: H2AT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

1071382:KAFR 0E03610
gene id: 1071382:KAFR_0E03610
uniprot id: H2AVW2
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A01950
gene id: 1071382:KAFR_0A01950
uniprot id: H2AMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

1071382:KAFR 0A06950
gene id: 1071382:KAFR_0A06950
uniprot id: H2AP30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

1071382:KAFR 0F03510
gene id: 1071382:KAFR_0F03510
uniprot id: H2AX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0I01110
gene id: 1071382:KAFR_0I01110
uniprot id: H2AZU2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071382:KAFR 0H00340
gene id: 1071382:KAFR_0H00340
uniprot id: H2AYN7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B05625
gene id: 1071382:KAFR_0B05625
uniprot id: H2AR58
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F00490
gene id: 1071382:KAFR_0F00490
uniprot id: H2AW96
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C06190
gene id: 1071382:KAFR_0C06190
uniprot id: H2ATB1
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1071382:KAFR 0I02740
gene id: 1071382:KAFR_0I02740
uniprot id: H2B0A3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0A06260
gene id: 1071382:KAFR_0A06260
uniprot id: H2ANW1
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

1071382:KAFR 0L01320
gene id: 1071382:KAFR_0L01320
uniprot id: H2B291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0A08130
gene id: 1071382:KAFR_0A08130
uniprot id: H2APE7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D01790
gene id: 1071382:KAFR_0D01790
uniprot id: H2ATX6
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1071382:KAFR 0B00330
gene id: 1071382:KAFR_0B00330
uniprot id: H2APN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0K00150
gene id: 1071382:KAFR_0K00150
uniprot id: H2B170
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E03340
gene id: 1071382:KAFR_0E03340
uniprot id: H2AT29
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071382:KAFR 0F00780
gene id: 1071382:KAFR_0F00780
uniprot id: H2AWC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

1071382:KAFR 0C04430
gene id: 1071382:KAFR_0C04430
uniprot id: H2AST3
names: Similarity
messages: Belongs to the peptidase M28 family.

1071382:KAFR 0E02930
gene id: 1071382:KAFR_0E02930
uniprot id: H2AVP5
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1071382:KAFR 0H00550
gene id: 1071382:KAFR_0H00550
uniprot id: H2AYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

1071382:KAFR 0G02400
gene id: 1071382:KAFR_0G02400
uniprot id: H2AY24
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1071382:KAFR 0A00510
gene id: 1071382:KAFR_0A00510
uniprot id: H2AM89
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

1071382:KAFR 0J01060
gene id: 1071382:KAFR_0J01060
uniprot id: H2B0M3
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

1071382:KAFR 0K01330
gene id: 1071382:KAFR_0K01330
uniprot id: H2B1I7
names: Similarity
messages: Belongs to the TFIIB family.

1071382:KAFR 0F02340
gene id: 1071382:KAFR_0F02340
uniprot id: H2AWT1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

1071382:KAFR 0B03120
gene id: 1071382:KAFR_0B03120
uniprot id: H2AQF8
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

1071382:KAFR 0F01230
gene id: 1071382:KAFR_0F01230
uniprot id: H2AWG9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1071382:KAFR 0B04640
gene id: 1071382:KAFR_0B04640
uniprot id: H2AQW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1071382:KAFR 0B04000
gene id: 1071382:KAFR_0B04000
uniprot id: H2AQP6
names: Similarity
messages: Belongs to the IlvD/Edd family.

1071382:KAFR 0L00890
gene id: 1071382:KAFR_0L00890
uniprot id: H2B247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0C01710
gene id: 1071382:KAFR_0C01710
uniprot id: H2AS14
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071382:KAFR 0A04760
gene id: 1071382:KAFR_0A04760
uniprot id: H2ANG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D01390
gene id: 1071382:KAFR_0D01390
uniprot id: H2ATT5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D03900
gene id: 1071382:KAFR_0D03900
uniprot id: H2AUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

1071382:KAFR 0A00560
gene id: 1071382:KAFR_0A00560
uniprot id: H2AM94
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0B06310
gene id: 1071382:KAFR_0B06310
uniprot id: H2ARC7
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

1071382:KAFR 0C00180
gene id: 1071382:KAFR_0C00180
uniprot id: H2ARL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0I00510
gene id: 1071382:KAFR_0I00510
uniprot id: H2AZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D00760
gene id: 1071382:KAFR_0D00760
uniprot id: H2ATM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0A08310
gene id: 1071382:KAFR_0A08310
uniprot id: H2APG5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1071382:KAFR 0L00950
gene id: 1071382:KAFR_0L00950
uniprot id: H2B253
names: Function
names: Similarity
messages: Belongs to the RGI1 family.
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

1071382:KAFR 0D02820
gene id: 1071382:KAFR_0D02820
uniprot id: H2AU80
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1071382:KAFR 0A03550
gene id: 1071382:KAFR_0A03550
uniprot id: H2AN40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071382:KAFR 0K01840
gene id: 1071382:KAFR_0K01840
uniprot id: H2B1N8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

1071382:KAFR 0C02200
gene id: 1071382:KAFR_0C02200
uniprot id: H2AS63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0G02680
gene id: 1071382:KAFR_0G02680
uniprot id: H2AY49
names: Similarity
messages: Belongs to the pirin family.

1071382:KAFR 0E00760
gene id: 1071382:KAFR_0E00760
uniprot id: H2AV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B01860
gene id: 1071382:KAFR_0B01860
uniprot id: H2AQ35
names: Similarity
messages: Belongs to the LOC1 family.

1071382:KAFR 0H01650
gene id: 1071382:KAFR_0H01650
uniprot id: H2AZ19
names: Similarity
messages: Belongs to the HMBS family.

1071382:KAFR 0F00890
gene id: 1071382:KAFR_0F00890
uniprot id: H2AWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0F01440
gene id: 1071382:KAFR_0F01440
uniprot id: H2AWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

1071382:KAFR 0G00140
gene id: 1071382:KAFR_0G00140
uniprot id: H2AXE7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H02120
gene id: 1071382:KAFR_0H02120
uniprot id: H2AZ65
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1071382:KAFR 0B04410
gene id: 1071382:KAFR_0B04410
uniprot id: H2AQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1071382:KAFR 0B01710
gene id: 1071382:KAFR_0B01710
uniprot id: H2AQ20
names: Similarity
messages: Belongs to the patched family.

1071382:KAFR 0F00250
gene id: 1071382:KAFR_0F00250
uniprot id: H2AW72
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071382:KAFR 0G03650
gene id: 1071382:KAFR_0G03650
uniprot id: H2AYE7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B04370
gene id: 1071382:KAFR_0B04370
uniprot id: H2AQT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1071382:KAFR 0D04720
gene id: 1071382:KAFR_0D04720
uniprot id: H2AUS0
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0B04250
gene id: 1071382:KAFR_0B04250
uniprot id: H2AQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1071382:KAFR 0A02390
gene id: 1071382:KAFR_0A02390
uniprot id: H2AMS7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1071382:KAFR 0H01020
gene id: 1071382:KAFR_0H01020
uniprot id: H2AYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1071382:KAFR 0F01860
gene id: 1071382:KAFR_0F01860
uniprot id: H2AWN3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1071382:KAFR 0D03590
gene id: 1071382:KAFR_0D03590
uniprot id: H2AUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0H01960
gene id: 1071382:KAFR_0H01960
uniprot id: H2AZ49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1071382:KAFR 0L02020
gene id: 1071382:KAFR_0L02020
uniprot id: H2B2G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071382:KAFR 0F01100
gene id: 1071382:KAFR_0F01100
uniprot id: H2AWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

1071382:KAFR 0C02510
gene id: 1071382:KAFR_0C02510
uniprot id: H2AS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

1071382:KAFR 0D04370
gene id: 1071382:KAFR_0D04370
uniprot id: H2AUN5
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

1071382:KAFR 0E01210
gene id: 1071382:KAFR_0E01210
uniprot id: H2AV75
names: Similarity
messages: Belongs to the VPS54 family.

1071382:KAFR 0E01640
gene id: 1071382:KAFR_0E01640
uniprot id: H2AVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

1071382:KAFR 0E02160
gene id: 1071382:KAFR_0E02160
uniprot id: H2AVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA11 family.
messages: Cytoplasm

1071382:KAFR 0A02740
gene id: 1071382:KAFR_0A02740
uniprot id: H2AMW0
names: Similarity
messages: Belongs to the sorting nexin family.

1071382:KAFR 0F03160
gene id: 1071382:KAFR_0F03160
uniprot id: H2AX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

1071382:KAFR 0C05750
gene id: 1071382:KAFR_0C05750
uniprot id: H2AT66
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

1071382:KAFR 0B06860
gene id: 1071382:KAFR_0B06860
uniprot id: H2ARI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D02690
gene id: 1071382:KAFR_0D02690
uniprot id: H2AU67
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

1071382:KAFR 0J02730
gene id: 1071382:KAFR_0J02730
uniprot id: H2B137
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

1071382:KAFR 0A05470
gene id: 1071382:KAFR_0A05470
uniprot id: H2ANN2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E01190
gene id: 1071382:KAFR_0E01190
uniprot id: H2AV73
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1071382:KAFR 0D02620
gene id: 1071382:KAFR_0D02620
uniprot id: H2AU60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1071382:KAFR 0B00830
gene id: 1071382:KAFR_0B00830
uniprot id: H2APT1
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

1071382:KAFR 0A06650
gene id: 1071382:KAFR_0A06650
uniprot id: H2AP00
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071382:KAFR 0G00690
gene id: 1071382:KAFR_0G00690
uniprot id: H2AXK2
names: Similarity
messages: Belongs to the dynein heavy chain family.

1071382:KAFR 0C01130
gene id: 1071382:KAFR_0C01130
uniprot id: H2ARV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

1071382:KAFR 0H00280
gene id: 1071382:KAFR_0H00280
uniprot id: H2AYN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0K01110
gene id: 1071382:KAFR_0K01110
uniprot id: H2B1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A03920
gene id: 1071382:KAFR_0A03920
uniprot id: H2AN77
names: Similarity
messages: Belongs to the APC5 family.

1071382:KAFR 0F03200
gene id: 1071382:KAFR_0F03200
uniprot id: H2AX16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1071382:KAFR 0C00100
gene id: 1071382:KAFR_0C00100
uniprot id: H2ARK8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01070
gene id: 1071382:KAFR_0H01070
uniprot id: H2AYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

1071382:KAFR 0B06170
gene id: 1071382:KAFR_0B06170
uniprot id: H2ARB4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0F02860
gene id: 1071382:KAFR_0F02860
uniprot id: H2AWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

1071382:KAFR 0C04620
gene id: 1071382:KAFR_0C04620
uniprot id: H2ASV3
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1071382:KAFR 0A04930
gene id: 1071382:KAFR_0A04930
uniprot id: H2ANH9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1071382:KAFR 0K01440
gene id: 1071382:KAFR_0K01440
uniprot id: H2B1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0D04670
gene id: 1071382:KAFR_0D04670
uniprot id: H2AUR5
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1071382:KAFR 0D03220
gene id: 1071382:KAFR_0D03220
uniprot id: H2AUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071382:KAFR 0H01950
gene id: 1071382:KAFR_0H01950
uniprot id: H2AZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0B02940
gene id: 1071382:KAFR_0B02940
uniprot id: H2AQE0
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1071382:KAFR 0E04140
gene id: 1071382:KAFR_0E04140
uniprot id: H2AW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1071382:KAFR 0G02070
gene id: 1071382:KAFR_0G02070
uniprot id: H2AXZ1
names: Similarity
messages: Belongs to the peptidase C14B family.

1071382:KAFR 0C05250
gene id: 1071382:KAFR_0C05250
uniprot id: H2AT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

1071382:KAFR 0I00790
gene id: 1071382:KAFR_0I00790
uniprot id: H2AZR0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071382:KAFR 0A05760
gene id: 1071382:KAFR_0A05760
uniprot id: H2ANR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

1071382:KAFR 0J00390
gene id: 1071382:KAFR_0J00390
uniprot id: H2B0F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071382:KAFR 0K01270
gene id: 1071382:KAFR_0K01270
uniprot id: H2B1I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1071382:KAFR 0B05480
gene id: 1071382:KAFR_0B05480
uniprot id: H2AR43
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1071382:KAFR 0A07890
gene id: 1071382:KAFR_0A07890
uniprot id: H2APC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E02990
gene id: 1071382:KAFR_0E02990
uniprot id: H2AVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

1071382:KAFR 0C02560
gene id: 1071382:KAFR_0C02560
uniprot id: H2AS99
names: Similarity
messages: Belongs to the RPAP2 family.

1071382:KAFR 0C01690
gene id: 1071382:KAFR_0C01690
uniprot id: H2AS12
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

1071382:KAFR 0B01760
gene id: 1071382:KAFR_0B01760
uniprot id: H2AQ25
names: Similarity
messages: Belongs to the RRP12 family.

1071382:KAFR 0K00220
gene id: 1071382:KAFR_0K00220
uniprot id: H2B177
names: Similarity
messages: Belongs to the CBP3 family.

1071382:KAFR 0K00440
gene id: 1071382:KAFR_0K00440
uniprot id: H2B199
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071382:KAFR 0E02690
gene id: 1071382:KAFR_0E02690
uniprot id: H2AVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

1071382:KAFR 0K00260
gene id: 1071382:KAFR_0K00260
uniprot id: H2B181
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

1071382:KAFR 0H02010
gene id: 1071382:KAFR_0H02010
uniprot id: H2AZ54
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071382:KAFR 0E01070
gene id: 1071382:KAFR_0E01070
uniprot id: H2AV61
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1071382:KAFR 0A01660
gene id: 1071382:KAFR_0A01660
uniprot id: H2AMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

1071382:KAFR 0E02270
gene id: 1071382:KAFR_0E02270
uniprot id: H2AVI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0G01330
gene id: 1071382:KAFR_0G01330
uniprot id: H2AXR7
names: Similarity
messages: Belongs to the BMT family.

1071382:KAFR 0H01270
gene id: 1071382:KAFR_0H01270
uniprot id: H2AYY1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0B01230
gene id: 1071382:KAFR_0B01230
uniprot id: H2APX2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071382:KAFR 0K01700
gene id: 1071382:KAFR_0K01700
uniprot id: H2B1M4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1071382:KAFR 0A06250
gene id: 1071382:KAFR_0A06250
uniprot id: H2ANW0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K01230
gene id: 1071382:KAFR_0K01230
uniprot id: H2B1H8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0K00970
gene id: 1071382:KAFR_0K00970
uniprot id: H2B1F3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0D02410
gene id: 1071382:KAFR_0D02410
uniprot id: H2AU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

1071382:KAFR 0D00650
gene id: 1071382:KAFR_0D00650
uniprot id: H2ATL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

1071382:KAFR 0F00450
gene id: 1071382:KAFR_0F00450
uniprot id: H2AW92
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

1071382:KAFR 0L00980
gene id: 1071382:KAFR_0L00980
uniprot id: H2B256
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

1071382:KAFR 0F02000
gene id: 1071382:KAFR_0F02000
uniprot id: H2AWP7
names: Similarity
messages: Belongs to the AIM23 family.

1071382:KAFR 0G00270
gene id: 1071382:KAFR_0G00270
uniprot id: H2AXG0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1071382:KAFR 0G03410
gene id: 1071382:KAFR_0G03410
uniprot id: H2AYC3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D04240
gene id: 1071382:KAFR_0D04240
uniprot id: H2AUM2
names: Similarity
messages: Belongs to the COG4 family.

1071382:KAFR 0I02800
gene id: 1071382:KAFR_0I02800
uniprot id: H2B0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

1071382:KAFR 0B04170
gene id: 1071382:KAFR_0B04170
uniprot id: H2AQR3
names: Similarity
messages: Belongs to the exportin family.

1071382:KAFR 0C01100
gene id: 1071382:KAFR_0C01100
uniprot id: H2ARV5
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071382:KAFR 0E01030
gene id: 1071382:KAFR_0E01030
uniprot id: H2AV57
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071382:KAFR 0C00800
gene id: 1071382:KAFR_0C00800
uniprot id: H2ARS5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0I02880
gene id: 1071382:KAFR_0I02880
uniprot id: H2B0B7
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

1071382:KAFR 0I02350
gene id: 1071382:KAFR_0I02350
uniprot id: H2B064
names: Similarity
messages: Belongs to the WrbA family.

1071382:KAFR 0A05480
gene id: 1071382:KAFR_0A05480
uniprot id: H2ANN3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C06400
gene id: 1071382:KAFR_0C06400
uniprot id: H2ATD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.

1071382:KAFR 0J02540
gene id: 1071382:KAFR_0J02540
uniprot id: H2B118
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

1071382:KAFR 0J02990
gene id: 1071382:KAFR_0J02990
uniprot id: H2B163
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1071382:KAFR 0G03010
gene id: 1071382:KAFR_0G03010
uniprot id: H2AY83
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A06230
gene id: 1071382:KAFR_0A06230
uniprot id: H2ANV8
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1071382:KAFR 0C03520
gene id: 1071382:KAFR_0C03520
uniprot id: H2ASJ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0F01280
gene id: 1071382:KAFR_0F01280
uniprot id: H2AWH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071382:KAFR 0C00850
gene id: 1071382:KAFR_0C00850
uniprot id: H2ART0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

1071382:KAFR 0A08140
gene id: 1071382:KAFR_0A08140
uniprot id: H2APE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool.
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

1071382:KAFR 0H01210
gene id: 1071382:KAFR_0H01210
uniprot id: H2AYX5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

1071382:KAFR 0A05350
gene id: 1071382:KAFR_0A05350
uniprot id: H2ANM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0A07550
gene id: 1071382:KAFR_0A07550
uniprot id: H2AP89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1071382:KAFR 0D04210
gene id: 1071382:KAFR_0D04210
uniprot id: H2AUL9
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071382:KAFR 0E04170
gene id: 1071382:KAFR_0E04170
uniprot id: H2AW18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

1071382:KAFR 0I02760
gene id: 1071382:KAFR_0I02760
uniprot id: H2B0A5
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

1071382:KAFR 0G00790
gene id: 1071382:KAFR_0G00790
uniprot id: H2AXL2
names: Similarity
messages: Belongs to the yippee family.

1071382:KAFR 0F03560
gene id: 1071382:KAFR_0F03560
uniprot id: H2AX52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1071382:KAFR 0A05630
gene id: 1071382:KAFR_0A05630
uniprot id: H2ANP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0A04530
gene id: 1071382:KAFR_0A04530
uniprot id: H2AND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1071382:KAFR 0L00200
gene id: 1071382:KAFR_0L00200
uniprot id: H2B1X7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

1071382:KAFR 0J02140
gene id: 1071382:KAFR_0J02140
uniprot id: H2B0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1071382:KAFR 0H01630
gene id: 1071382:KAFR_0H01630
uniprot id: H2AZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

1071382:KAFR 0C02590
gene id: 1071382:KAFR_0C02590
uniprot id: H2ASA2
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0B04840
gene id: 1071382:KAFR_0B04840
uniprot id: H2AQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

1071382:KAFR 0A06850
gene id: 1071382:KAFR_0A06850
uniprot id: H2AP20
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

1071382:KAFR 0F01870
gene id: 1071382:KAFR_0F01870
uniprot id: H2AWN4
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071382:KAFR 0A00620
gene id: 1071382:KAFR_0A00620
uniprot id: H2AMA0
names: Similarity
messages: Belongs to the MUB1/samB family.

1071382:KAFR 0H00850
gene id: 1071382:KAFR_0H00850
uniprot id: H2AYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

1071382:KAFR 0A07720
gene id: 1071382:KAFR_0A07720
uniprot id: H2APA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

1071382:KAFR 0A07090
gene id: 1071382:KAFR_0A07090
uniprot id: H2AP43
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

1071382:KAFR 0E01380
gene id: 1071382:KAFR_0E01380
uniprot id: H2AV92
names: Similarity
messages: Belongs to the group II decarboxylase family.

1071382:KAFR 0B03550
gene id: 1071382:KAFR_0B03550
uniprot id: H2AQK2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

1071382:KAFR 0C05160
gene id: 1071382:KAFR_0C05160
uniprot id: H2AT07
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F01550
gene id: 1071382:KAFR_0F01550
uniprot id: H2AWK2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A02560
gene id: 1071382:KAFR_0A02560
uniprot id: H2AMU2
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0J00460
gene id: 1071382:KAFR_0J00460
uniprot id: H2B0G4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1071382:KAFR 0D00380
gene id: 1071382:KAFR_0D00380
uniprot id: H2ATI5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0F00330
gene id: 1071382:KAFR_0F00330
uniprot id: H2AW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

1071382:KAFR 0B04850
gene id: 1071382:KAFR_0B04850
uniprot id: H2AQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0F01960
gene id: 1071382:KAFR_0F01960
uniprot id: H2AWP3
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0I01230
gene id: 1071382:KAFR_0I01230
uniprot id: H2AZV4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1071382:KAFR 0B03540
gene id: 1071382:KAFR_0B03540
uniprot id: H2AQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071382:KAFR 0F02040
gene id: 1071382:KAFR_0F02040
uniprot id: H2AWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1071382:KAFR 0C00310
gene id: 1071382:KAFR_0C00310
uniprot id: H2ARM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0H03320
gene id: 1071382:KAFR_0H03320
uniprot id: H2AZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

1071382:KAFR 0E01610
gene id: 1071382:KAFR_0E01610
uniprot id: H2AVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A04800
gene id: 1071382:KAFR_0A04800
uniprot id: H2ANG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

1071382:KAFR 0C01530
gene id: 1071382:KAFR_0C01530
uniprot id: H2ARZ6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B05510
gene id: 1071382:KAFR_0B05510
uniprot id: H2AR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D02310
gene id: 1071382:KAFR_0D02310
uniprot id: H2AU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A01280
gene id: 1071382:KAFR_0A01280
uniprot id: H2B0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0A02410
gene id: 1071382:KAFR_0A02410
uniprot id: H2AMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071382:KAFR 0A04580
gene id: 1071382:KAFR_0A04580
uniprot id: H2ANE3
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

1071382:KAFR 0L01090
gene id: 1071382:KAFR_0L01090
uniprot id: H2B267
names: Similarity
messages: Belongs to the peptidase M24B family.

1071382:KAFR 0C02750
gene id: 1071382:KAFR_0C02750
uniprot id: H2ASB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

1071382:KAFR 0E01540
gene id: 1071382:KAFR_0E01540
uniprot id: H2AVA8
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

1071382:KAFR 0A02040
gene id: 1071382:KAFR_0A02040
uniprot id: H2AMP2
names: Similarity
messages: Belongs to the NifU family.

1071382:KAFR 0G03370
gene id: 1071382:KAFR_0G03370
uniprot id: H2AYB9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1071382:KAFR 0B05910
gene id: 1071382:KAFR_0B05910
uniprot id: H2AR87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

1071382:KAFR 0C02400
gene id: 1071382:KAFR_0C02400
uniprot id: H2AS83
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1071382:KAFR 0K00510
gene id: 1071382:KAFR_0K00510
uniprot id: H2B1A6
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1071382:KAFR 0F03700
gene id: 1071382:KAFR_0F03700
uniprot id: H2AX66
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0J01350
gene id: 1071382:KAFR_0J01350
uniprot id: H2B0Q2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

1071382:KAFR 0A05990
gene id: 1071382:KAFR_0A05990
uniprot id: H2ANT4
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0B01850
gene id: 1071382:KAFR_0B01850
uniprot id: H2AQ34
names: Similarity
messages: Belongs to the citrate synthase family.

1071382:KAFR 0F01580
gene id: 1071382:KAFR_0F01580
uniprot id: H2AWK5
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

1071382:KAFR 0D03620
gene id: 1071382:KAFR_0D03620
uniprot id: H2AUG0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1071382:KAFR 0D01070
gene id: 1071382:KAFR_0D01070
uniprot id: H2ATQ3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1071382:KAFR 0A04970
gene id: 1071382:KAFR_0A04970
uniprot id: H2ANI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1071382:KAFR 0B06760
gene id: 1071382:KAFR_0B06760
uniprot id: H2ARH3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B05200
gene id: 1071382:KAFR_0B05200
uniprot id: H2AR16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1071382:KAFR 0A04610
gene id: 1071382:KAFR_0A04610
uniprot id: H2ANE6
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1071382:KAFR 0G03030
gene id: 1071382:KAFR_0G03030
uniprot id: H2AY85
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0H02590
gene id: 1071382:KAFR_0H02590
uniprot id: H2AZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0C01660
gene id: 1071382:KAFR_0C01660
uniprot id: H2AS09
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1071382:KAFR 0B06080
gene id: 1071382:KAFR_0B06080
uniprot id: H2ARA4
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

1071382:KAFR 0C05130
gene id: 1071382:KAFR_0C05130
uniprot id: H2AT04
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1071382:KAFR 0K01380
gene id: 1071382:KAFR_0K01380
uniprot id: H2B1J2
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

1071382:KAFR 0C01050
gene id: 1071382:KAFR_0C01050
uniprot id: H2ARV0
names: Similarity
messages: Belongs to the SF3A3 family.

1071382:KAFR 0K02340
gene id: 1071382:KAFR_0K02340
uniprot id: H2B1T9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071382:KAFR 0A03210
gene id: 1071382:KAFR_0A03210
uniprot id: H2AN06
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

1071382:KAFR 0B02170
gene id: 1071382:KAFR_0B02170
uniprot id: H2AQ65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

1071382:KAFR 0E03170
gene id: 1071382:KAFR_0E03170
uniprot id: H2AVR9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071382:KAFR 0F02190
gene id: 1071382:KAFR_0F02190
uniprot id: H2AWR6
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0B00510
gene id: 1071382:KAFR_0B00510
uniprot id: H2APQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

1071382:KAFR 0E04460
gene id: 1071382:KAFR_0E04460
uniprot id: H2AW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071382:KAFR 0C04680
gene id: 1071382:KAFR_0C04680
uniprot id: H2ASV9
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1071382:KAFR 0F02610
gene id: 1071382:KAFR_0F02610
uniprot id: H2AWV8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0I02010
gene id: 1071382:KAFR_0I02010
uniprot id: H2B031
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0H00230
gene id: 1071382:KAFR_0H00230
uniprot id: H2AYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1071382:KAFR 0A00690
gene id: 1071382:KAFR_0A00690
uniprot id: H2AMA7
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0G02930
gene id: 1071382:KAFR_0G02930
uniprot id: H2AY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

1071382:KAFR 0J01920
gene id: 1071382:KAFR_0J01920
uniprot id: H2B0V6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

1071382:KAFR 0F02710
gene id: 1071382:KAFR_0F02710
uniprot id: H2AWW8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1071382:KAFR 0B06960
gene id: 1071382:KAFR_0B06960
uniprot id: H2ARJ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1071382:KAFR 0F02800
gene id: 1071382:KAFR_0F02800
uniprot id: H2AWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0H01000
gene id: 1071382:KAFR_0H01000
uniprot id: H2AYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0C00290
gene id: 1071382:KAFR_0C00290
uniprot id: H2ARM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

1071382:KAFR 0B02570
gene id: 1071382:KAFR_0B02570
uniprot id: H2AQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1071382:KAFR 0F01300
gene id: 1071382:KAFR_0F01300
uniprot id: H2AWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071382:KAFR 0D04060
gene id: 1071382:KAFR_0D04060
uniprot id: H2AUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1071382:KAFR 0A05200
gene id: 1071382:KAFR_0A05200
uniprot id: H2ANK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

1071382:KAFR 0I02700
gene id: 1071382:KAFR_0I02700
uniprot id: H2B099
names: Similarity
messages: Belongs to the ELP6 family.

1071382:KAFR 0K00380
gene id: 1071382:KAFR_0K00380
uniprot id: H2B193
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

1071382:KAFR 0L01120
gene id: 1071382:KAFR_0L01120
uniprot id: H2B270
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0A04430
gene id: 1071382:KAFR_0A04430
uniprot id: H2ANC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

1071382:KAFR 0B06020
gene id: 1071382:KAFR_0B06020
uniprot id: H2AR98
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1071382:KAFR 0B06240
gene id: 1071382:KAFR_0B06240
uniprot id: H2ARC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

1071382:KAFR 0J02330
gene id: 1071382:KAFR_0J02330
uniprot id: H2B0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071382:KAFR 0K00570
gene id: 1071382:KAFR_0K00570
uniprot id: H2B1B2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

1071382:KAFR 0H03660
gene id: 1071382:KAFR_0H03660
uniprot id: H2AYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071382:KAFR 0E00490
gene id: 1071382:KAFR_0E00490
uniprot id: H2AV03
names: Similarity
messages: Belongs to the NAD kinase family.

1071382:KAFR 0B03360
gene id: 1071382:KAFR_0B03360
uniprot id: H2AQI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071382:KAFR 0H03000
gene id: 1071382:KAFR_0H03000
uniprot id: H2AZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071382:KAFR 0D03070
gene id: 1071382:KAFR_0D03070
uniprot id: H2AUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0B06330
gene id: 1071382:KAFR_0B06330
uniprot id: H2ARC9
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1071382:KAFR 0E02820
gene id: 1071382:KAFR_0E02820
uniprot id: H2AVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

1071382:KAFR 0H00290
gene id: 1071382:KAFR_0H00290
uniprot id: H2AYN2
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

1071382:KAFR 0A04010
gene id: 1071382:KAFR_0A04010
uniprot id: H2AN86
names: Similarity
messages: Belongs to the AAA ATPase family.

1071382:KAFR 0B02540
gene id: 1071382:KAFR_0B02540
uniprot id: H2AQA1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1071382:KAFR 0F03680
gene id: 1071382:KAFR_0F03680
uniprot id: H2AX64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1071382:KAFR 0D03480
gene id: 1071382:KAFR_0D03480
uniprot id: H2AUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071382:KAFR 0A07860
gene id: 1071382:KAFR_0A07860
uniprot id: H2APC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

1071382:KAFR 0K02170
gene id: 1071382:KAFR_0K02170
uniprot id: H2B1S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071382:KAFR 0H03280
gene id: 1071382:KAFR_0H03280
uniprot id: H2AZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

1071382:KAFR 0D03040
gene id: 1071382:KAFR_0D03040
uniprot id: H2AUA2
names: Similarity
messages: Belongs to the SSH4 family.

1071382:KAFR 0E03880
gene id: 1071382:KAFR_0E03880
uniprot id: H2AVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

1071382:KAFR 0H02530
gene id: 1071382:KAFR_0H02530
uniprot id: H2AZA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1071382:KAFR 0B01610
gene id: 1071382:KAFR_0B01610
uniprot id: H2AQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1071382:KAFR 0A08500
gene id: 1071382:KAFR_0A08500
uniprot id: H2API4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

1071382:KAFR 0K02360
gene id: 1071382:KAFR_0K02360
uniprot id: H2B1U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

1071382:KAFR 0F03380
gene id: 1071382:KAFR_0F03380
uniprot id: H2AX34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

1071382:KAFR 0A06640
gene id: 1071382:KAFR_0A06640
uniprot id: H2ANZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071382:KAFR 0L01040
gene id: 1071382:KAFR_0L01040
uniprot id: H2B262
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0B00270
gene id: 1071382:KAFR_0B00270
uniprot id: H2APM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0D01280
gene id: 1071382:KAFR_0D01280
uniprot id: H2ATS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1071382:KAFR 0A05690
gene id: 1071382:KAFR_0A05690
uniprot id: H2ANQ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0D01000
gene id: 1071382:KAFR_0D01000
uniprot id: H2ATP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071382:KAFR 0E00460
gene id: 1071382:KAFR_0E00460
uniprot id: H2AV00
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D00260
gene id: 1071382:KAFR_0D00260
uniprot id: H2ATH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0J01680
gene id: 1071382:KAFR_0J01680
uniprot id: H2B0T3
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A03790
gene id: 1071382:KAFR_0A03790
uniprot id: H2AN64
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C04670
gene id: 1071382:KAFR_0C04670
uniprot id: H2ASV8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1071382:KAFR 0A06610
gene id: 1071382:KAFR_0A06610
uniprot id: H2ANZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

1071382:KAFR 0G02940
gene id: 1071382:KAFR_0G02940
uniprot id: H2AMV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071382:KAFR 0E03220
gene id: 1071382:KAFR_0E03220
uniprot id: H2AVS4
names: Similarity
messages: Belongs to the TAF11 family.

1071382:KAFR 0F01750
gene id: 1071382:KAFR_0F01750
uniprot id: H2AWM2
names: Similarity
messages: Belongs to the peptidase M20A family.

1071382:KAFR 0D00850
gene id: 1071382:KAFR_0D00850
uniprot id: H2ATN2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1071382:KAFR 0I02630
gene id: 1071382:KAFR_0I02630
uniprot id: H2B092
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071382:KAFR 0B02320
gene id: 1071382:KAFR_0B02320
uniprot id: H2AQ80
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

1071382:KAFR 0E01780
gene id: 1071382:KAFR_0E01780
uniprot id: H2AVD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

1071382:KAFR 0E04150
gene id: 1071382:KAFR_0E04150
uniprot id: H2AW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

1071382:KAFR 0D01410
gene id: 1071382:KAFR_0D01410
uniprot id: H2ATT7
names: Similarity
messages: Belongs to the peptidase S10 family.

1071382:KAFR 0E01460
gene id: 1071382:KAFR_0E01460
uniprot id: H2AVA0
names: Similarity
messages: Belongs to the glutaredoxin family.

1071382:KAFR 0A01730
gene id: 1071382:KAFR_0A01730
uniprot id: H2AML1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Membrane

1071382:KAFR 0E03490
gene id: 1071382:KAFR_0E03490
uniprot id: H2AVV0
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1071382:KAFR 0G03750
gene id: 1071382:KAFR_0G03750
uniprot id: H2AYF8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A06190
gene id: 1071382:KAFR_0A06190
uniprot id: H2ANV4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

1071382:KAFR 0A03020
gene id: 1071382:KAFR_0A03020
uniprot id: H2AMY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

1071382:KAFR 0K01650
gene id: 1071382:KAFR_0K01650
uniprot id: H2B1L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071382:KAFR 0I00500
gene id: 1071382:KAFR_0I00500
uniprot id: H2AZN1
names: Similarity
messages: Belongs to the WD repeat coronin family.

1071382:KAFR 0J00320
gene id: 1071382:KAFR_0J00320
uniprot id: H2B0F0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C03310
gene id: 1071382:KAFR_0C03310
uniprot id: H2ASH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1071382:KAFR 0F03180
gene id: 1071382:KAFR_0F03180
uniprot id: H2AX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1071382:KAFR 0I02280
gene id: 1071382:KAFR_0I02280
uniprot id: H2B057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

1071382:KAFR 0D04700
gene id: 1071382:KAFR_0D04700
uniprot id: H2AUR8
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

1071382:KAFR 0J02920
gene id: 1071382:KAFR_0J02920
uniprot id: H2B156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

1071382:KAFR 0C00920
gene id: 1071382:KAFR_0C00920
uniprot id: H2ART7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0E01510
gene id: 1071382:KAFR_0E01510
uniprot id: H2AVA5
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1071382:KAFR 0A06750
gene id: 1071382:KAFR_0A06750
uniprot id: H2AP10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

1071382:KAFR 0K02490
gene id: 1071382:KAFR_0K02490
uniprot id: H2B1V5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1071382:KAFR 0D04570
gene id: 1071382:KAFR_0D04570
uniprot id: H2AUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0D03120
gene id: 1071382:KAFR_0D03120
uniprot id: H2AUB0
names: Similarity
messages: Belongs to the KTI12 family.

1071382:KAFR 0L00820
gene id: 1071382:KAFR_0L00820
uniprot id: H2B240
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

1071382:KAFR 0A04620
gene id: 1071382:KAFR_0A04620
uniprot id: H2ANE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

1071382:KAFR 0J02510
gene id: 1071382:KAFR_0J02510
uniprot id: H2B115
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0F03630
gene id: 1071382:KAFR_0F03630
uniprot id: H2AX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

1071382:KAFR 0F04410
gene id: 1071382:KAFR_0F04410
uniprot id: H2AXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0I02100
gene id: 1071382:KAFR_0I02100
uniprot id: H2B040
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0I01620
gene id: 1071382:KAFR_0I01620
uniprot id: H2AZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071382:KAFR 0F01140
gene id: 1071382:KAFR_0F01140
uniprot id: H2AWG0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1071382:KAFR 0G00130
gene id: 1071382:KAFR_0G00130
uniprot id: H2AXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071382:KAFR 0J02490
gene id: 1071382:KAFR_0J02490
uniprot id: H2B113
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

1071382:KAFR 0H02820
gene id: 1071382:KAFR_0H02820
uniprot id: H2AZD5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0D00670
gene id: 1071382:KAFR_0D00670
uniprot id: H2ATL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

1071382:KAFR 0F02010
gene id: 1071382:KAFR_0F02010
uniprot id: H2AWP8
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

1071382:KAFR 0C03430
gene id: 1071382:KAFR_0C03430
uniprot id: H2ASI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

1071382:KAFR 0E00540
gene id: 1071382:KAFR_0E00540
uniprot id: H2AV08
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

1071382:KAFR 0F04350
gene id: 1071382:KAFR_0F04350
uniprot id: H2AXD0
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0E01430
gene id: 1071382:KAFR_0E01430
uniprot id: H2AV97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

1071382:KAFR 0A04740
gene id: 1071382:KAFR_0A04740
uniprot id: H2ANF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

1071382:KAFR 0A08180
gene id: 1071382:KAFR_0A08180
uniprot id: H2APF2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G01400
gene id: 1071382:KAFR_0G01400
uniprot id: H2AXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0G01550
gene id: 1071382:KAFR_0G01550
uniprot id: H2AXT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

1071382:KAFR 0L00560
gene id: 1071382:KAFR_0L00560
uniprot id: H2B213
names: Similarity
messages: Belongs to the SEC3 family.

1071382:KAFR 0I02210
gene id: 1071382:KAFR_0I02210
uniprot id: H2B050
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1071382:KAFR 0I02520
gene id: 1071382:KAFR_0I02520
uniprot id: H2B081
names: Similarity
messages: Belongs to the peptidase S10 family.

1071382:KAFR 0E04110
gene id: 1071382:KAFR_0E04110
uniprot id: H2AW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1071382:KAFR 0D00540
gene id: 1071382:KAFR_0D00540
uniprot id: H2ATK1
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

1071382:KAFR 0B01890
gene id: 1071382:KAFR_0B01890
uniprot id: H2AQ38
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071382:KAFR 0D00950
gene id: 1071382:KAFR_0D00950
uniprot id: H2ATP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0A06040
gene id: 1071382:KAFR_0A06040
uniprot id: H2ANT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

1071382:KAFR 0L01300
gene id: 1071382:KAFR_0L01300
uniprot id: H2B289
names: Similarity
messages: Belongs to the UPP synthase family.

1071382:KAFR 0E00860
gene id: 1071382:KAFR_0E00860
uniprot id: H2AV40
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071382:KAFR 0C03120
gene id: 1071382:KAFR_0C03120
uniprot id: H2ASF4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E03380
gene id: 1071382:KAFR_0E03380
uniprot id: H2AVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

1071382:KAFR 0A02370
gene id: 1071382:KAFR_0A02370
uniprot id: H2AMS5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

1071382:KAFR 0I02850
gene id: 1071382:KAFR_0I02850
uniprot id: H2B0B4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A03280
gene id: 1071382:KAFR_0A03280
uniprot id: H2AN13
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1071382:KAFR 0H03120
gene id: 1071382:KAFR_0H03120
uniprot id: H2AZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0G01440
gene id: 1071382:KAFR_0G01440
uniprot id: H2AXS8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0K00750
gene id: 1071382:KAFR_0K00750
uniprot id: H2B1D0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0B06000
gene id: 1071382:KAFR_0B06000
uniprot id: H2AR96
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1071382:KAFR 0B04650
gene id: 1071382:KAFR_0B04650
uniprot id: H2AQW2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

1071382:KAFR 0E03530
gene id: 1071382:KAFR_0E03530
uniprot id: H2AVV4
names: Similarity
messages: Belongs to the IUNH family.

1071382:KAFR 0F01220
gene id: 1071382:KAFR_0F01220
uniprot id: H2AWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

1071382:KAFR 0L01020
gene id: 1071382:KAFR_0L01020
uniprot id: H2B260
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection
messages: Cytoplasm

1071382:KAFR 0I02110
gene id: 1071382:KAFR_0I02110
uniprot id: H2B041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

1071382:KAFR 0D03160
gene id: 1071382:KAFR_0D03160
uniprot id: H2AUB4
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

1071382:KAFR 0K02450
gene id: 1071382:KAFR_0K02450
uniprot id: H2B1V1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1071382:KAFR 0J00710
gene id: 1071382:KAFR_0J00710
uniprot id: H2B0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

1071382:KAFR 0D02550
gene id: 1071382:KAFR_0D02550
uniprot id: H2AU52
names: Similarity
messages: Belongs to the PP2C family.

1071382:KAFR 0F03880
gene id: 1071382:KAFR_0F03880
uniprot id: H2AX84
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L00640
gene id: 1071382:KAFR_0L00640
uniprot id: H2B221
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071382:KAFR 0H02230
gene id: 1071382:KAFR_0H02230
uniprot id: H2AZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.

1071382:KAFR 0D01920
gene id: 1071382:KAFR_0D01920
uniprot id: H2ATY9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1071382:KAFR 0C00880
gene id: 1071382:KAFR_0C00880
uniprot id: H2ART3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

1071382:KAFR 0L01930
gene id: 1071382:KAFR_0L01930
uniprot id: H2B2F3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1071382:KAFR 0A02310
gene id: 1071382:KAFR_0A02310
uniprot id: H2AMR9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

1071382:KAFR 0D00900
gene id: 1071382:KAFR_0D00900
uniprot id: H2ATN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

1071382:KAFR 0G02040
gene id: 1071382:KAFR_0G02040
uniprot id: H2AXY8
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

1071382:KAFR 0A02160
gene id: 1071382:KAFR_0A02160
uniprot id: H2AMQ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0A00570
gene id: 1071382:KAFR_0A00570
uniprot id: H2AM95
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1071382:KAFR 0B05840
gene id: 1071382:KAFR_0B05840
uniprot id: H2AR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

1071382:KAFR 0B01570
gene id: 1071382:KAFR_0B01570
uniprot id: H2AQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0C06460
gene id: 1071382:KAFR_0C06460
uniprot id: H2ATE2
names: Similarity
messages: Belongs to the CWC22 family.

1071382:KAFR 0A00420
gene id: 1071382:KAFR_0A00420
uniprot id: H2AM80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

1071382:KAFR 0C01440
gene id: 1071382:KAFR_0C01440
uniprot id: H2ARY7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1071382:KAFR 0A06800
gene id: 1071382:KAFR_0A06800
uniprot id: H2AP15
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071382:KAFR 0I02270
gene id: 1071382:KAFR_0I02270
uniprot id: H2B056
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

1071382:KAFR 0D04980
gene id: 1071382:KAFR_0D04980
uniprot id: H2AUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0E01100
gene id: 1071382:KAFR_0E01100
uniprot id: H2AV64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

1071382:KAFR 0A07450
gene id: 1071382:KAFR_0A07450
uniprot id: H2AP79
names: Similarity
messages: Belongs to the FAH family.

1071382:KAFR 0E01820
gene id: 1071382:KAFR_0E01820
uniprot id: H2AVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

1071382:KAFR 0C02730
gene id: 1071382:KAFR_0C02730
uniprot id: H2ASB6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0D02650
gene id: 1071382:KAFR_0D02650
uniprot id: H2AU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

1071382:KAFR 0K02020
gene id: 1071382:KAFR_0K02020
uniprot id: H2B1Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24 family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

1071382:KAFR 0J02530
gene id: 1071382:KAFR_0J02530
uniprot id: H2B117
names: Similarity
messages: Belongs to the threonine synthase family.

1071382:KAFR 0A02610
gene id: 1071382:KAFR_0A02610
uniprot id: H2AMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

1071382:KAFR 0L01350
gene id: 1071382:KAFR_0L01350
uniprot id: H2B294
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1071382:KAFR 0B06250
gene id: 1071382:KAFR_0B06250
uniprot id: H2ARC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0C05220
gene id: 1071382:KAFR_0C05220
uniprot id: H2AT13
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A08190
gene id: 1071382:KAFR_0A08190
uniprot id: H2APF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1071382:KAFR 0G03700
gene id: 1071382:KAFR_0G03700
uniprot id: H2AYF3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J01340
gene id: 1071382:KAFR_0J01340
uniprot id: H2B0Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

1071382:KAFR 0B00770
gene id: 1071382:KAFR_0B00770
uniprot id: H2APS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

1071382:KAFR 0E01360
gene id: 1071382:KAFR_0E01360
uniprot id: H2AV90
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.

1071382:KAFR 0G00810
gene id: 1071382:KAFR_0G00810
uniprot id: H2AXL4
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

1071382:KAFR 0J02280
gene id: 1071382:KAFR_0J02280
uniprot id: H2B0Z2
names: Similarity
messages: Belongs to the CAP family.

1071382:KAFR 0G01540
gene id: 1071382:KAFR_0G01540
uniprot id: H2AXT8
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0A04890
gene id: 1071382:KAFR_0A04890
uniprot id: H2ANH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1071382:KAFR 0K02440
gene id: 1071382:KAFR_0K02440
uniprot id: H2B1V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

1071382:KAFR 0B06160
gene id: 1071382:KAFR_0B06160
uniprot id: H2ARB2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071382:KAFR 0B03290
gene id: 1071382:KAFR_0B03290
uniprot id: H2AQH6
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

1071382:KAFR 0C01560
gene id: 1071382:KAFR_0C01560
uniprot id: H2ARZ9
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0H01620
gene id: 1071382:KAFR_0H01620
uniprot id: H2AZ16
names: Function
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RRM CWC2 family.
messages: Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.

1071382:KAFR 0D01720
gene id: 1071382:KAFR_0D01720
uniprot id: H2ATW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

1071382:KAFR 0F01690
gene id: 1071382:KAFR_0F01690
uniprot id: H2AWL6
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071382:KAFR 0E04130
gene id: 1071382:KAFR_0E04130
uniprot id: H2AW14
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1071382:KAFR 0D01710
gene id: 1071382:KAFR_0D01710
uniprot id: H2ATW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D01850
gene id: 1071382:KAFR_0D01850
uniprot id: H2ATY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

1071382:KAFR 0I00900
gene id: 1071382:KAFR_0I00900
uniprot id: H2AZS1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071382:KAFR 0A01210
gene id: 1071382:KAFR_0A01210
uniprot id: H2AMG0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0G00390
gene id: 1071382:KAFR_0G00390
uniprot id: H2AXH2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H03100
gene id: 1071382:KAFR_0H03100
uniprot id: H2AZG4
names: Similarity
messages: Belongs to the UPF0357 family.

1071382:KAFR 0H00360
gene id: 1071382:KAFR_0H00360
uniprot id: H2AYN9
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

1071382:KAFR 0B02500
gene id: 1071382:KAFR_0B02500
uniprot id: H2AQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

1071382:KAFR 0K01450
gene id: 1071382:KAFR_0K01450
uniprot id: H2B1J9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071382:KAFR 0K00950
gene id: 1071382:KAFR_0K00950
uniprot id: H2B1F1
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

1071382:KAFR 0F04240
gene id: 1071382:KAFR_0F04240
uniprot id: H2AXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

1071382:KAFR 0L01010
gene id: 1071382:KAFR_0L01010
uniprot id: H2B259
names: Similarity
messages: Belongs to the SEC6 family.

1071382:KAFR 0C01370
gene id: 1071382:KAFR_0C01370
uniprot id: H2ARY0
names: Subunit
messages: Monomer.

1071382:KAFR 0F02050
gene id: 1071382:KAFR_0F02050
uniprot id: H2AWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1071382:KAFR 0A06330
gene id: 1071382:KAFR_0A06330
uniprot id: H2ANW8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C05030
gene id: 1071382:KAFR_0C05030
uniprot id: H2ASZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

1071382:KAFR 0A05320
gene id: 1071382:KAFR_0A05320
uniprot id: H2ANL7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0K01280
gene id: 1071382:KAFR_0K01280
uniprot id: H2B1I2
names: Similarity
messages: Belongs to the UPF0538 family.

1071382:KAFR 0A06340
gene id: 1071382:KAFR_0A06340
uniprot id: H2ANW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0A05290
gene id: 1071382:KAFR_0A05290
uniprot id: H2ANL4
names: Subcellular Location Annotation
messages: Nucleus membrane

1071382:KAFR 0D00330
gene id: 1071382:KAFR_0D00330
uniprot id: H2ATI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

1071382:KAFR 0D03010
gene id: 1071382:KAFR_0D03010
uniprot id: H2AU99
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1071382:KAFR 0F01310
gene id: 1071382:KAFR_0F01310
uniprot id: H2AWH7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I02150
gene id: 1071382:KAFR_0I02150
uniprot id: H2B045
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1071382:KAFR 0A02670
gene id: 1071382:KAFR_0A02670
uniprot id: H2AMV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071382:KAFR 0I01400
gene id: 1071382:KAFR_0I01400
uniprot id: H2AZX1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0B04560
gene id: 1071382:KAFR_0B04560
uniprot id: H2AQV3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071382:KAFR 0C00840
gene id: 1071382:KAFR_0C00840
uniprot id: H2ARS9
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C06410
gene id: 1071382:KAFR_0C06410
uniprot id: H2ATD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071382:KAFR 0B06350
gene id: 1071382:KAFR_0B06350
uniprot id: H2ARD1
names: Similarity
messages: Belongs to the AHA1 family.

1071382:KAFR 0A02050
gene id: 1071382:KAFR_0A02050
uniprot id: H2AMP3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1071382:KAFR 0D03830
gene id: 1071382:KAFR_0D03830
uniprot id: H2AUI1
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

1071382:KAFR 0C04720
gene id: 1071382:KAFR_0C04720
uniprot id: H2ASW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

1071382:KAFR 0A05510
gene id: 1071382:KAFR_0A05510
uniprot id: H2ANN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

1071382:KAFR 0A02780
gene id: 1071382:KAFR_0A02780
uniprot id: H2AMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

1071382:KAFR 0B06850
gene id: 1071382:KAFR_0B06850
uniprot id: H2ARI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

1071382:KAFR 0F02410
gene id: 1071382:KAFR_0F02410
uniprot id: H2AWT8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C01820
gene id: 1071382:KAFR_0C01820
uniprot id: H2AS25
names: Similarity
messages: Belongs to the asparaginase 1 family.

1071382:KAFR 0G03730
gene id: 1071382:KAFR_0G03730
uniprot id: H2AYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

1071382:KAFR 0B01370
gene id: 1071382:KAFR_0B01370
uniprot id: H2APY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

1071382:KAFR 0G01080
gene id: 1071382:KAFR_0G01080
uniprot id: H2AXP1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

1071382:KAFR 0C00610
gene id: 1071382:KAFR_0C00610
uniprot id: H2ARQ6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1071382:KAFR 0A05000
gene id: 1071382:KAFR_0A05000
uniprot id: H2ANI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

1071382:KAFR 0J01510
gene id: 1071382:KAFR_0J01510
uniprot id: H2B0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

1071382:KAFR 0D03890
gene id: 1071382:KAFR_0D03890
uniprot id: H2AUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

1071382:KAFR 0E03040
gene id: 1071382:KAFR_0E03040
uniprot id: H2AVQ6
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071382:KAFR 0J01460
gene id: 1071382:KAFR_0J01460
uniprot id: H2B0R2
names: Similarity
messages: Belongs to the SHQ1 family.

1071382:KAFR 0G01610
gene id: 1071382:KAFR_0G01610
uniprot id: H2AXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

1071382:KAFR 0B06010
gene id: 1071382:KAFR_0B06010
uniprot id: H2AR97
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

1071382:KAFR 0B03640
gene id: 1071382:KAFR_0B03640
uniprot id: H2AQL1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1071382:KAFR 0I01860
gene id: 1071382:KAFR_0I01860
uniprot id: H2B016
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0A08200
gene id: 1071382:KAFR_0A08200
uniprot id: H2APF4
names: Similarity
messages: Belongs to the AHA1 family.

1071382:KAFR 0B06730
gene id: 1071382:KAFR_0B06730
uniprot id: H2ARH0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0J01960
gene id: 1071382:KAFR_0J01960
uniprot id: H2B0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0A08410
gene id: 1071382:KAFR_0A08410
uniprot id: H2APH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1071382:KAFR 0B01830
gene id: 1071382:KAFR_0B01830
uniprot id: H2AQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

1071382:KAFR 0B04120
gene id: 1071382:KAFR_0B04120
uniprot id: H2AQQ8
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1071382:KAFR 0C03380
gene id: 1071382:KAFR_0C03380
uniprot id: H2ASI0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E00570
gene id: 1071382:KAFR_0E00570
uniprot id: H2AV11
names: Similarity
messages: Belongs to the pyridoxine kinase family.

1071382:KAFR 0H02250
gene id: 1071382:KAFR_0H02250
uniprot id: H2AZ78
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071382:KAFR 0E01830
gene id: 1071382:KAFR_0E01830
uniprot id: H2AVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

1071382:KAFR 0K00730
gene id: 1071382:KAFR_0K00730
uniprot id: H2B1C8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A08270
gene id: 1071382:KAFR_0A08270
uniprot id: H2APG1
names: Similarity
messages: Belongs to the CNOT9 family.

1071382:KAFR 0A04150
gene id: 1071382:KAFR_0A04150
uniprot id: H2ANA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

1071382:KAFR 0K02410
gene id: 1071382:KAFR_0K02410
uniprot id: H2B1U7
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

1071382:KAFR 0H00220
gene id: 1071382:KAFR_0H00220
uniprot id: H2AYM5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

1071382:KAFR 0L01240
gene id: 1071382:KAFR_0L01240
uniprot id: H2B282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

1071382:KAFR 0J01780
gene id: 1071382:KAFR_0J01780
uniprot id: H2B0U2
names: Similarity
messages: Belongs to the MAD2 family.

1071382:KAFR 0H03670
gene id: 1071382:KAFR_0H03670
uniprot id: H2AYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071382:KAFR 0K02070
gene id: 1071382:KAFR_0K02070
uniprot id: H2B1R1
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0E02860
gene id: 1071382:KAFR_0E02860
uniprot id: H2AVN8
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1071382:KAFR 0A03390
gene id: 1071382:KAFR_0A03390
uniprot id: H2AN24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

1071382:KAFR 0L01400
gene id: 1071382:KAFR_0L01400
uniprot id: H2B299
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

1071382:KAFR 0B02220
gene id: 1071382:KAFR_0B02220
uniprot id: H2AQ70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1071382:KAFR 0F02530
gene id: 1071382:KAFR_0F02530
uniprot id: H2AWV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

1071382:KAFR 0G01680
gene id: 1071382:KAFR_0G01680
uniprot id: H2AXV2
names: Similarity
messages: Belongs to the EME1/MMS4 family.

1071382:KAFR 0I02360
gene id: 1071382:KAFR_0I02360
uniprot id: H2B065
names: Similarity
messages: Belongs to the citrate synthase family.

1071382:KAFR 0L01290
gene id: 1071382:KAFR_0L01290
uniprot id: H2B288
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1071382:KAFR 0A08640
gene id: 1071382:KAFR_0A08640
uniprot id: H2APJ8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1071382:KAFR 0C04010
gene id: 1071382:KAFR_0C04010
uniprot id: H2ASP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

1071382:KAFR 0E01760
gene id: 1071382:KAFR_0E01760
uniprot id: H2AVD0
names: Similarity
messages: Belongs to the peptidase M16 family.

1071382:KAFR 0C01380
gene id: 1071382:KAFR_0C01380
uniprot id: H2ARY1
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071382:KAFR 0I00480
gene id: 1071382:KAFR_0I00480
uniprot id: H2AZM9
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

1071382:KAFR 0A03110
gene id: 1071382:KAFR_0A03110
uniprot id: H2AMZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0G02500
gene id: 1071382:KAFR_0G02500
uniprot id: H2AY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0F02470
gene id: 1071382:KAFR_0F02470
uniprot id: H2AWU4
names: Similarity
messages: Belongs to the UPF0045 family.

1071382:KAFR 0H02840
gene id: 1071382:KAFR_0H02840
uniprot id: H2AZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

1071382:KAFR 0E00520
gene id: 1071382:KAFR_0E00520
uniprot id: H2AV06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1071382:KAFR 0C00640
gene id: 1071382:KAFR_0C00640
uniprot id: H2ARQ9
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1071382:KAFR 0J01080
gene id: 1071382:KAFR_0J01080
uniprot id: H2B0M5
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0D00870
gene id: 1071382:KAFR_0D00870
uniprot id: H2ATN4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

1071382:KAFR 0D03270
gene id: 1071382:KAFR_0D03270
uniprot id: H2AUC5
names: Similarity
messages: Belongs to the ISF1/MBR1 family.

1071382:KAFR 0A01760
gene id: 1071382:KAFR_0A01760
uniprot id: H2AML4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1071382:KAFR 0J00870
gene id: 1071382:KAFR_0J00870
uniprot id: H2B0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071382:KAFR 0E00750
gene id: 1071382:KAFR_0E00750
uniprot id: H2AV29
names: Similarity
messages: Belongs to the transglutaminase-like superfamily. PNGase family.

1071382:KAFR 0A02000
gene id: 1071382:KAFR_0A02000
uniprot id: H2AMN8
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071382:KAFR 0A05080
gene id: 1071382:KAFR_0A05080
uniprot id: H2ANJ4
names: Similarity
messages: Belongs to the pirin family.

1071382:KAFR 0H01240
gene id: 1071382:KAFR_0H01240
uniprot id: H2AYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0G00330
gene id: 1071382:KAFR_0G00330
uniprot id: H2AXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

1071382:KAFR 0J01760
gene id: 1071382:KAFR_0J01760
uniprot id: H2B0U0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0E00340
gene id: 1071382:KAFR_0E00340
uniprot id: H2AUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

1071382:KAFR 0G00470
gene id: 1071382:KAFR_0G00470
uniprot id: H2AXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

1071382:KAFR 0D01880
gene id: 1071382:KAFR_0D01880
uniprot id: H2ATY5
names: Similarity
messages: Belongs to the EFG1 family.

1071382:KAFR 0A04640
gene id: 1071382:KAFR_0A04640
uniprot id: H2ANE9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0L01550
gene id: 1071382:KAFR_0L01550
uniprot id: H2B2B5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1071382:KAFR 0E00880
gene id: 1071382:KAFR_0E00880
uniprot id: H2AV42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

1071382:KAFR 0G02350
gene id: 1071382:KAFR_0G02350
uniprot id: H2AY19
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071382:KAFR 0E01080
gene id: 1071382:KAFR_0E01080
uniprot id: H2AV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

1071382:KAFR 0K02100
gene id: 1071382:KAFR_0K02100
uniprot id: H2B1R4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1071382:KAFR 0B03390
gene id: 1071382:KAFR_0B03390
uniprot id: H2AQI6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

1071382:KAFR 0E02220
gene id: 1071382:KAFR_0E02220
uniprot id: H2AVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

1071382:KAFR 0J01160
gene id: 1071382:KAFR_0J01160
uniprot id: H2B0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

1071382:KAFR 0C03260
gene id: 1071382:KAFR_0C03260
uniprot id: H2ASG8
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0I02380
gene id: 1071382:KAFR_0I02380
uniprot id: H2B067
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1071382:KAFR 0E01990
gene id: 1071382:KAFR_0E01990
uniprot id: H2AVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

1071382:KAFR 0C01290
gene id: 1071382:KAFR_0C01290
uniprot id: H2ARX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071382:KAFR 0D03330
gene id: 1071382:KAFR_0D03330
uniprot id: H2AUD1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1071382:KAFR 0K00830
gene id: 1071382:KAFR_0K00830
uniprot id: H2B1D8
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

1071382:KAFR 0F04100
gene id: 1071382:KAFR_0F04100
uniprot id: H2AXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1071382:KAFR 0A06940
gene id: 1071382:KAFR_0A06940
uniprot id: H2AP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

1071382:KAFR 0E02020
gene id: 1071382:KAFR_0E02020
uniprot id: H2AVF5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071382:KAFR 0A08050
gene id: 1071382:KAFR_0A08050
uniprot id: H2APD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

1071382:KAFR 0C00390
gene id: 1071382:KAFR_0C00390
uniprot id: H2ARN4
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0C05270
gene id: 1071382:KAFR_0C05270
uniprot id: H2AT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

1071382:KAFR 0B00240
gene id: 1071382:KAFR_0B00240
uniprot id: H2APM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071382:KAFR 0C01420
gene id: 1071382:KAFR_0C01420
uniprot id: H2ARY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1071382:KAFR 0C03640
gene id: 1071382:KAFR_0C03640
uniprot id: H2ASK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1071382:KAFR 0H02900
gene id: 1071382:KAFR_0H02900
uniprot id: H2AZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

1071382:KAFR 0A05880
gene id: 1071382:KAFR_0A05880
uniprot id: H2ANS3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1071382:KAFR 0A08230
gene id: 1071382:KAFR_0A08230
uniprot id: H2APF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1071382:KAFR 0H01100
gene id: 1071382:KAFR_0H01100
uniprot id: H2AYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

1071382:KAFR 0I00840
gene id: 1071382:KAFR_0I00840
uniprot id: H2AZR5
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0D03730
gene id: 1071382:KAFR_0D03730
uniprot id: H2AUH1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1071382:KAFR 0J00110
gene id: 1071382:KAFR_0J00110
uniprot id: H2B0C9
names: Similarity
messages: Belongs to the hexokinase family.

1071382:KAFR 0A08080
gene id: 1071382:KAFR_0A08080
uniprot id: H2APE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

1071382:KAFR 0D00520
gene id: 1071382:KAFR_0D00520
uniprot id: H2ATJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0A01900
gene id: 1071382:KAFR_0A01900
uniprot id: H2AMM8
names: Similarity
messages: Belongs to the PDCD5 family.

1071382:KAFR 0B02920
gene id: 1071382:KAFR_0B02920
uniprot id: H2AQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

1071382:KAFR 0I00680
gene id: 1071382:KAFR_0I00680
uniprot id: H2AZP9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1071382:KAFR 0A07620
gene id: 1071382:KAFR_0A07620
uniprot id: H2AP96
names: Similarity
messages: Belongs to the importin alpha family.

1071382:KAFR 0H03410
gene id: 1071382:KAFR_0H03410
uniprot id: H2AYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

1071382:KAFR 0E03030
gene id: 1071382:KAFR_0E03030
uniprot id: H2AVQ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0D01760
gene id: 1071382:KAFR_0D01760
uniprot id: H2ATX3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071382:KAFR 0H00430
gene id: 1071382:KAFR_0H00430
uniprot id: H2AYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

1071382:KAFR 0B02560
gene id: 1071382:KAFR_0B02560
uniprot id: H2AQA3
names: Similarity
messages: Belongs to the adenylate kinase family.

1071382:KAFR 0H03620
gene id: 1071382:KAFR_0H03620
uniprot id: H2AYJ5
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

1071382:KAFR 0H01030
gene id: 1071382:KAFR_0H01030
uniprot id: H2AYV7
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071382:KAFR 0A05900
gene id: 1071382:KAFR_0A05900
uniprot id: H2ANS5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071382:KAFR 0J02600
gene id: 1071382:KAFR_0J02600
uniprot id: H2B124
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0K01710
gene id: 1071382:KAFR_0K01710
uniprot id: H2B1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

1071382:KAFR 0A02060
gene id: 1071382:KAFR_0A02060
uniprot id: H2AMP4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071382:KAFR 0B01000
gene id: 1071382:KAFR_0B01000
uniprot id: H2APU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

1071382:KAFR 0C05890
gene id: 1071382:KAFR_0C05890
uniprot id: H2AT80
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0E04410
gene id: 1071382:KAFR_0E04410
uniprot id: H2AW41
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1071382:KAFR 0A03410
gene id: 1071382:KAFR_0A03410
uniprot id: H2AN26
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0G01190
gene id: 1071382:KAFR_0G01190
uniprot id: H2AXQ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

1071382:KAFR 0I01290
gene id: 1071382:KAFR_0I01290
uniprot id: H2AZW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1071382:KAFR 0L01940
gene id: 1071382:KAFR_0L01940
uniprot id: H2B2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071382:KAFR 0A05230
gene id: 1071382:KAFR_0A05230
uniprot id: H2ANK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071382:KAFR 0G00170
gene id: 1071382:KAFR_0G00170
uniprot id: H2AXF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071382:KAFR 0H03560
gene id: 1071382:KAFR_0H03560
uniprot id: H2AYI8
names: Similarity
messages: Belongs to the NOP9 family.

1071382:KAFR 0A06290
gene id: 1071382:KAFR_0A06290
uniprot id: H2ANW4
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1071382:KAFR 0A00260
gene id: 1071382:KAFR_0A00260
uniprot id: H2AM64
names: Similarity
messages: Belongs to the small Tim family.

1071382:KAFR 0A03490
gene id: 1071382:KAFR_0A03490
uniprot id: H2AN34
names: Similarity
messages: Belongs to the SAPS family.

1071382:KAFR 0L00370
gene id: 1071382:KAFR_0L00370
uniprot id: H2B1Z4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071382:KAFR 0B03210
gene id: 1071382:KAFR_0B03210
uniprot id: H2AQG7
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

1071382:KAFR 0J01210
gene id: 1071382:KAFR_0J01210
uniprot id: H2B0N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

1071382:KAFR 0C02800
gene id: 1071382:KAFR_0C02800
uniprot id: H2ASC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

1071382:KAFR 0E00850
gene id: 1071382:KAFR_0E00850
uniprot id: H2AV39
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0A03200
gene id: 1071382:KAFR_0A03200
uniprot id: H2AN05
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1071382:KAFR 0A07600
gene id: 1071382:KAFR_0A07600
uniprot id: H2AP94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0D03190
gene id: 1071382:KAFR_0D03190
uniprot id: H2AUB7
names: Similarity
messages: Belongs to the peptidase M18 family.

1071382:KAFR 0D02880
gene id: 1071382:KAFR_0D02880
uniprot id: H2AU86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

1071382:KAFR 0D02480
gene id: 1071382:KAFR_0D02480
uniprot id: H2AU45
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1071382:KAFR 0J00410
gene id: 1071382:KAFR_0J00410
uniprot id: H2B0F9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

1071382:KAFR 0B03470
gene id: 1071382:KAFR_0B03470
uniprot id: H2AQJ4
names: Similarity
messages: Belongs to the MBF1 family.

1071382:KAFR 0D05120
gene id: 1071382:KAFR_0D05120
uniprot id: H2AUV9
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

1071382:KAFR 0A06790
gene id: 1071382:KAFR_0A06790
uniprot id: H2AP14
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

1071382:KAFR 0G00370
gene id: 1071382:KAFR_0G00370
uniprot id: H2AXH0
names: Similarity
messages: Belongs to the LST4 family.

1071382:KAFR 0D04600
gene id: 1071382:KAFR_0D04600
uniprot id: H2AUQ8
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

1071382:KAFR 0E03680
gene id: 1071382:KAFR_0E03680
uniprot id: H2AVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071382:KAFR 0F02080
gene id: 1071382:KAFR_0F02080
uniprot id: H2AWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

1071382:KAFR 0B02470
gene id: 1071382:KAFR_0B02470
uniprot id: H2AQ95
names: Similarity
messages: Belongs to the XPC family.

1071382:KAFR 0A04950
gene id: 1071382:KAFR_0A04950
uniprot id: H2ANI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1071382:KAFR 0A07170
gene id: 1071382:KAFR_0A07170
uniprot id: H2AP51
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1071382:KAFR 0J02300
gene id: 1071382:KAFR_0J02300
uniprot id: H2B0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

1071382:KAFR 0B00340
gene id: 1071382:KAFR_0B00340
uniprot id: H2APN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1071382:KAFR 0C00870
gene id: 1071382:KAFR_0C00870
uniprot id: H2ART2
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071382:KAFR 0D05140
gene id: 1071382:KAFR_0D05140
uniprot id: H2AUW1
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E01550
gene id: 1071382:KAFR_0E01550
uniprot id: H2AVA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0A00920
gene id: 1071382:KAFR_0A00920
uniprot id: H2AMD0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

1071382:KAFR 0D04820
gene id: 1071382:KAFR_0D04820
uniprot id: H2AUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

1071382:KAFR 0D04660
gene id: 1071382:KAFR_0D04660
uniprot id: H2AUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

1071382:KAFR 0C04190
gene id: 1071382:KAFR_0C04190
uniprot id: H2ASR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0G00450
gene id: 1071382:KAFR_0G00450
uniprot id: H2AXH8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1071382:KAFR 0J00470
gene id: 1071382:KAFR_0J00470
uniprot id: H2B0G5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0G03580
gene id: 1071382:KAFR_0G03580
uniprot id: H2AYE0
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0E03730
gene id: 1071382:KAFR_0E03730
uniprot id: H2AVX4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071382:KAFR 0D04620
gene id: 1071382:KAFR_0D04620
uniprot id: H2AUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

1071382:KAFR 0H02870
gene id: 1071382:KAFR_0H02870
uniprot id: H2AZE0
names: Similarity
messages: Belongs to the OMP decarboxylase family.

1071382:KAFR 0G03140
gene id: 1071382:KAFR_0G03140
uniprot id: H2AY96
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H03060
gene id: 1071382:KAFR_0H03060
uniprot id: H2AZG0
names: Similarity
messages: Belongs to the WrbA family.

1071382:KAFR 0B02030
gene id: 1071382:KAFR_0B02030
uniprot id: H2AQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

1071382:KAFR 0D01970
gene id: 1071382:KAFR_0D01970
uniprot id: H2ATZ4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I01920
gene id: 1071382:KAFR_0I01920
uniprot id: H2B022
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071382:KAFR 0F00760
gene id: 1071382:KAFR_0F00760
uniprot id: H2AWC3
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

1071382:KAFR 0B01210
gene id: 1071382:KAFR_0B01210
uniprot id: H2APX0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071382:KAFR 0H02730
gene id: 1071382:KAFR_0H02730
uniprot id: H2AZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

1071382:KAFR 0H03430
gene id: 1071382:KAFR_0H03430
uniprot id: H2AYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

1071382:KAFR 0K00820
gene id: 1071382:KAFR_0K00820
uniprot id: H2B1D7
names: Similarity
messages: Belongs to the TOP6A family.

1071382:KAFR 0D01290
gene id: 1071382:KAFR_0D01290
uniprot id: H2ATS5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071382:KAFR 0H01640
gene id: 1071382:KAFR_0H01640
uniprot id: H2AZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071382:KAFR 0F02370
gene id: 1071382:KAFR_0F02370
uniprot id: H2AWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

1071382:KAFR 0A04310
gene id: 1071382:KAFR_0A04310
uniprot id: H2ANB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1071382:KAFR 0J00900
gene id: 1071382:KAFR_0J00900
uniprot id: H2B0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

1071382:KAFR 0E04050
gene id: 1071382:KAFR_0E04050
uniprot id: H2AW06
names: Subcellular Location Annotation
messages: Golgi apparatus

1071382:KAFR 0L01910
gene id: 1071382:KAFR_0L01910
uniprot id: H2B2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071382:KAFR 0D00940
gene id: 1071382:KAFR_0D00940
uniprot id: H2ATP1
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

1071382:KAFR 0D01800
gene id: 1071382:KAFR_0D01800
uniprot id: H2ATX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

1071382:KAFR 0K00280
gene id: 1071382:KAFR_0K00280
uniprot id: H2B183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

1071382:KAFR 0L01430
gene id: 1071382:KAFR_0L01430
uniprot id: H2B2A2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1071382:KAFR 0E02600
gene id: 1071382:KAFR_0E02600
uniprot id: H2AVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1071382:KAFR 0A00470
gene id: 1071382:KAFR_0A00470
uniprot id: H2AM85
names: Similarity
messages: Belongs to the PurH family.

1071382:KAFR 0C04600
gene id: 1071382:KAFR_0C04600
uniprot id: H2ASV1
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0A06890
gene id: 1071382:KAFR_0A06890
uniprot id: H2AP24
names: Similarity
messages: Belongs to the frataxin family.

1071382:KAFR 0K00690
gene id: 1071382:KAFR_0K00690
uniprot id: H2B1C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

1071382:KAFR 0E01630
gene id: 1071382:KAFR_0E01630
uniprot id: H2AVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

1071382:KAFR 0D02460
gene id: 1071382:KAFR_0D02460
uniprot id: H2AU43
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1071382:KAFR 0A00830
gene id: 1071382:KAFR_0A00830
uniprot id: H2AMC1
names: Similarity
messages: Belongs to the VPS26 family.

1071382:KAFR 0D04180
gene id: 1071382:KAFR_0D04180
uniprot id: H2AUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

1071382:KAFR 0F03210
gene id: 1071382:KAFR_0F03210
uniprot id: H2AX17
names: Similarity
messages: Belongs to the HscB family.

1071382:KAFR 0I00700
gene id: 1071382:KAFR_0I00700
uniprot id: H2AZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071382:KAFR 0D02940
gene id: 1071382:KAFR_0D02940
uniprot id: H2AU92
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1071382:KAFR 0D02950
gene id: 1071382:KAFR_0D02950
uniprot id: H2AU93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1071382:KAFR 0A03610
gene id: 1071382:KAFR_0A03610
uniprot id: H2AN46
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0E00310
gene id: 1071382:KAFR_0E00310
uniprot id: H2AUY5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

1071382:KAFR 0I02080
gene id: 1071382:KAFR_0I02080
uniprot id: H2B038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Golgi apparatus

1071382:KAFR 0D03340
gene id: 1071382:KAFR_0D03340
uniprot id: H2AUD2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I02310
gene id: 1071382:KAFR_0I02310
uniprot id: H2B060
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0D04130
gene id: 1071382:KAFR_0D04130
uniprot id: H2AUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0B05900
gene id: 1071382:KAFR_0B05900
uniprot id: H2AR86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

1071382:KAFR 0A07930
gene id: 1071382:KAFR_0A07930
uniprot id: H2APC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SQS1 family.
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0B03570
gene id: 1071382:KAFR_0B03570
uniprot id: H2AQK4
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0J00130
gene id: 1071382:KAFR_0J00130
uniprot id: H2B0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071382:KAFR 0A06520
gene id: 1071382:KAFR_0A06520
uniprot id: H2ANY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus
messages: Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is essential for mitotic growth and required for cell cycle progression.

1071382:KAFR 0A04170
gene id: 1071382:KAFR_0A04170
uniprot id: H2ANA2
names: Subunit
messages: Homodimer.

1071382:KAFR 0F00680
gene id: 1071382:KAFR_0F00680
uniprot id: H2AWB5
names: Similarity
messages: Belongs to the MIP18 family.

1071382:KAFR 0D00750
gene id: 1071382:KAFR_0D00750
uniprot id: H2ATM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0C04170
gene id: 1071382:KAFR_0C04170
uniprot id: H2ASQ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1071382:KAFR 0A08040
gene id: 1071382:KAFR_0A08040
uniprot id: H2APD8
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

1071382:KAFR 0A02440
gene id: 1071382:KAFR_0A02440
uniprot id: H2AMT2
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0L01310
gene id: 1071382:KAFR_0L01310
uniprot id: H2B290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071382:KAFR 0H01540
gene id: 1071382:KAFR_0H01540
uniprot id: H2AZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

1071382:KAFR 0A00610
gene id: 1071382:KAFR_0A00610
uniprot id: H2AM99
names: Similarity
messages: Belongs to the UPP synthase family.

1071382:KAFR 0D00280
gene id: 1071382:KAFR_0D00280
uniprot id: H2ATH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0E02560
gene id: 1071382:KAFR_0E02560
uniprot id: H2AVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071382:KAFR 0E03070
gene id: 1071382:KAFR_0E03070
uniprot id: H2AVQ9
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

1071382:KAFR 0A07060
gene id: 1071382:KAFR_0A07060
uniprot id: H2AP40
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A01790
gene id: 1071382:KAFR_0A01790
uniprot id: H2AML7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1071382:KAFR 0K00720
gene id: 1071382:KAFR_0K00720
uniprot id: H2B1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

1071382:KAFR 0F00220
gene id: 1071382:KAFR_0F00220
uniprot id: H2AW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0B03850
gene id: 1071382:KAFR_0B03850
uniprot id: H2AQN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0D00700
gene id: 1071382:KAFR_0D00700
uniprot id: H2ATL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0E03910
gene id: 1071382:KAFR_0E03910
uniprot id: H2AVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

1071382:KAFR 0A01800
gene id: 1071382:KAFR_0A01800
uniprot id: H2AML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1071382:KAFR 0H01570
gene id: 1071382:KAFR_0H01570
uniprot id: H2AZ11
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0H03070
gene id: 1071382:KAFR_0H03070
uniprot id: H2AZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

1071382:KAFR 0B01040
gene id: 1071382:KAFR_0B01040
uniprot id: H2APV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

1071382:KAFR 0A04840
gene id: 1071382:KAFR_0A04840
uniprot id: H2ANH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

1071382:KAFR 0K01520
gene id: 1071382:KAFR_0K01520
uniprot id: H2B1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

1071382:KAFR 0G03100
gene id: 1071382:KAFR_0G03100
uniprot id: H2AY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

1071382:KAFR 0K02060
gene id: 1071382:KAFR_0K02060
uniprot id: H2B1R0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071382:KAFR 0A02630
gene id: 1071382:KAFR_0A02630
uniprot id: H2AMU9
names: Similarity
messages: Belongs to the peptidase C48 family.

1071382:KAFR 0H01970
gene id: 1071382:KAFR_0H01970
uniprot id: H2AZ50
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1071382:KAFR 0H00800
gene id: 1071382:KAFR_0H00800
uniprot id: H2AU58
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071382:KAFR 0F01680
gene id: 1071382:KAFR_0F01680
uniprot id: H2AWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1071382:KAFR 0A04820
gene id: 1071382:KAFR_0A04820
uniprot id: H2ANG8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071382:KAFR 0F00560
gene id: 1071382:KAFR_0F00560
uniprot id: H2AWA3
names: Similarity
messages: Belongs to the peptidase M14 family.

1071382:KAFR 0K00780
gene id: 1071382:KAFR_0K00780
uniprot id: H2B1D3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

1071382:KAFR 0F00550
gene id: 1071382:KAFR_0F00550
uniprot id: H2AWA2
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

1071382:KAFR 0E00690
gene id: 1071382:KAFR_0E00690
uniprot id: H2AV23
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

1071382:KAFR 0J00880
gene id: 1071382:KAFR_0J00880
uniprot id: H2B0K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1071382:KAFR 0H01860
gene id: 1071382:KAFR_0H01860
uniprot id: H2AZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071382:KAFR 0D02440
gene id: 1071382:KAFR_0D02440
uniprot id: H2AU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071382:KAFR 0H03490
gene id: 1071382:KAFR_0H03490
uniprot id: H2AYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

1071382:KAFR 0F01590
gene id: 1071382:KAFR_0F01590
uniprot id: H2AWK6
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I01930
gene id: 1071382:KAFR_0I01930
uniprot id: H2B023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1071382:KAFR 0D01320
gene id: 1071382:KAFR_0D01320
uniprot id: H2ATS8
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

1071382:KAFR 0A04080
gene id: 1071382:KAFR_0A04080
uniprot id: H2AN93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

1071382:KAFR 0C00900
gene id: 1071382:KAFR_0C00900
uniprot id: H2ART5
names: Subcellular Location Annotation
messages: Cytoplasm

1071382:KAFR 0G02700
gene id: 1071382:KAFR_0G02700
uniprot id: H2AY51
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1071382:KAFR 0G01090
gene id: 1071382:KAFR_0G01090
uniprot id: H2AXP2
names: Similarity
messages: Belongs to the WD repeat mio family.

1071382:KAFR 0A05750
gene id: 1071382:KAFR_0A05750
uniprot id: H2ANR0
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A07220
gene id: 1071382:KAFR_0A07220
uniprot id: H2AP56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1071382:KAFR 0E02040
gene id: 1071382:KAFR_0E02040
uniprot id: H2AVF7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0G02560
gene id: 1071382:KAFR_0G02560
uniprot id: H2AY38
names: Similarity
messages: Belongs to the GET4 family.

1071382:KAFR 0L01480
gene id: 1071382:KAFR_0L01480
uniprot id: H2B2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

1071382:KAFR 0I00890
gene id: 1071382:KAFR_0I00890
uniprot id: H2AZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

1071382:KAFR 0I02640
gene id: 1071382:KAFR_0I02640
uniprot id: H2B093
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071382:KAFR 0A05120
gene id: 1071382:KAFR_0A05120
uniprot id: H2ANJ7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0J01010
gene id: 1071382:KAFR_0J01010
uniprot id: H2B0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

1071382:KAFR 0G01760
gene id: 1071382:KAFR_0G01760
uniprot id: H2AXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

1071382:KAFR 0I00440
gene id: 1071382:KAFR_0I00440
uniprot id: H2AZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

1071382:KAFR 0G03660
gene id: 1071382:KAFR_0G03660
uniprot id: H2AYE8
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071382:KAFR 0B06320
gene id: 1071382:KAFR_0B06320
uniprot id: H2ARC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

1071382:KAFR 0D04000
gene id: 1071382:KAFR_0D04000
uniprot id: H2AUJ8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

1071382:KAFR 0A06710
gene id: 1071382:KAFR_0A06710
uniprot id: H2AP06
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1071382:KAFR 0A06980
gene id: 1071382:KAFR_0A06980
uniprot id: H2AP33
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

1071382:KAFR 0G02970
gene id: 1071382:KAFR_0G02970
uniprot id: H2AY79
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

1071382:KAFR 0F03290
gene id: 1071382:KAFR_0F03290
uniprot id: H2AX25
names: Similarity
messages: Belongs to the cullin family.

1071382:KAFR 0E00140
gene id: 1071382:KAFR_0E00140
uniprot id: H2AUW8
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0H01740
gene id: 1071382:KAFR_0H01740
uniprot id: H2AZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071382:KAFR 0G00240
gene id: 1071382:KAFR_0G00240
uniprot id: H2AXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071382:KAFR 0K01530
gene id: 1071382:KAFR_0K01530
uniprot id: H2B1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

1071382:KAFR 0E02760
gene id: 1071382:KAFR_0E02760
uniprot id: H2AVM8
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

1071382:KAFR 0A02110
gene id: 1071382:KAFR_0A02110
uniprot id: H2AMP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071382:KAFR 0A08670
gene id: 1071382:KAFR_0A08670
uniprot id: H2APK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

1071382:KAFR 0I00530
gene id: 1071382:KAFR_0I00530
uniprot id: H2AZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0A05380
gene id: 1071382:KAFR_0A05380
uniprot id: H2ANM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1071382:KAFR 0C03850
gene id: 1071382:KAFR_0C03850
uniprot id: H2ASM6
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

1071382:KAFR 0A00790
gene id: 1071382:KAFR_0A00790
uniprot id: H2AMB6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071382:KAFR 0K01880
gene id: 1071382:KAFR_0K01880
uniprot id: H2B1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

1071382:KAFR 0E03580
gene id: 1071382:KAFR_0E03580
uniprot id: H2AVV9
names: Similarity
messages: Belongs to the AAA ATPase family.

1071382:KAFR 0C02850
gene id: 1071382:KAFR_0C02850
uniprot id: H2ASC8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1071382:KAFR 0B04440
gene id: 1071382:KAFR_0B04440
uniprot id: H2AQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071382:KAFR 0B06610
gene id: 1071382:KAFR_0B06610
uniprot id: H2ARF7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

1071382:KAFR 0A02270
gene id: 1071382:KAFR_0A02270
uniprot id: H2AMR5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0I00600
gene id: 1071382:KAFR_0I00600
uniprot id: H2AZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

1071382:KAFR 0A00740
gene id: 1071382:KAFR_0A00740
uniprot id: H2AMB2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071382:KAFR 0A01870
gene id: 1071382:KAFR_0A01870
uniprot id: H2AMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

1071382:KAFR 0B01730
gene id: 1071382:KAFR_0B01730
uniprot id: H2AQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

1071382:KAFR 0E02290
gene id: 1071382:KAFR_0E02290
uniprot id: H2AVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1071382:KAFR 0G00830
gene id: 1071382:KAFR_0G00830
uniprot id: H2AXL6
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1071382:KAFR 0H01900
gene id: 1071382:KAFR_0H01900
uniprot id: H2AZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071382:KAFR 0B03530
gene id: 1071382:KAFR_0B03530
uniprot id: H2AQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0C05730
gene id: 1071382:KAFR_0C05730
uniprot id: H2AT64
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071382:KAFR 0H01940
gene id: 1071382:KAFR_0H01940
uniprot id: H2AZ47
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071382:KAFR 0J00770
gene id: 1071382:KAFR_0J00770
uniprot id: H2B0J5
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071382:KAFR 0A05970
gene id: 1071382:KAFR_0A05970
uniprot id: H2ANT2
names: Similarity
messages: Belongs to the peptidase M16 family.

1071382:KAFR 0C00980
gene id: 1071382:KAFR_0C00980
uniprot id: H2ARU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0B02980
gene id: 1071382:KAFR_0B02980
uniprot id: H2AQE4
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

1071382:KAFR 0A02930
gene id: 1071382:KAFR_0A02930
uniprot id: H2AMX9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071382:KAFR 0H01750
gene id: 1071382:KAFR_0H01750
uniprot id: H2AZ29
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0E03150
gene id: 1071382:KAFR_0E03150
uniprot id: H2AVR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1071382:KAFR 0A05390
gene id: 1071382:KAFR_0A05390
uniprot id: H2ANM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

1071382:KAFR 0A00890
gene id: 1071382:KAFR_0A00890
uniprot id: H2AMC7
names: Similarity
messages: Belongs to the cullin family.

1071382:KAFR 0F01800
gene id: 1071382:KAFR_0F01800
uniprot id: H2AWM7
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0J00380
gene id: 1071382:KAFR_0J00380
uniprot id: H2B0F6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071382:KAFR 0D05030
gene id: 1071382:KAFR_0D05030
uniprot id: H2AUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1071382:KAFR 0C00190
gene id: 1071382:KAFR_0C00190
uniprot id: H2ARL5
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A00630
gene id: 1071382:KAFR_0A00630
uniprot id: H2AMA1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

1071382:KAFR 0C02280
gene id: 1071382:KAFR_0C02280
uniprot id: H2AS71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

1071382:KAFR 0B02010
gene id: 1071382:KAFR_0B02010
uniprot id: H2AQ49
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

1071382:KAFR 0A01000
gene id: 1071382:KAFR_0A01000
uniprot id: H2AMD8
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0K01350
gene id: 1071382:KAFR_0K01350
uniprot id: H2B1I9
names: Similarity
messages: Belongs to the CCZ1 family.

1071382:KAFR 0C02240
gene id: 1071382:KAFR_0C02240
uniprot id: H2AS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPS2 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
messages: Membrane
messages: Nucleus membrane
messages: spindle pole body

1071382:KAFR 0C00270
gene id: 1071382:KAFR_0C00270
uniprot id: H2ARM3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071382:KAFR 0C01760
gene id: 1071382:KAFR_0C01760
uniprot id: H2AS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

1071382:KAFR 0A07350
gene id: 1071382:KAFR_0A07350
uniprot id: H2AP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1071382:KAFR 0J00300
gene id: 1071382:KAFR_0J00300
uniprot id: H2B0E8
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

1071382:KAFR 0G02840
gene id: 1071382:KAFR_0G02840
uniprot id: H2AY66
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1071382:KAFR 0I00720
gene id: 1071382:KAFR_0I00720
uniprot id: H2AZQ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1071382:KAFR 0C04860
gene id: 1071382:KAFR_0C04860
uniprot id: H2ASX7
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C04120
gene id: 1071382:KAFR_0C04120
uniprot id: H2ASQ3
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

1071382:KAFR 0D04080
gene id: 1071382:KAFR_0D04080
uniprot id: H2AUK6
names: Similarity
messages: Belongs to the multicopper oxidase family.

1071382:KAFR 0G01510
gene id: 1071382:KAFR_0G01510
uniprot id: H2AXT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

1071382:KAFR 0F01500
gene id: 1071382:KAFR_0F01500
uniprot id: H2AWJ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071382:KAFR 0H03390
gene id: 1071382:KAFR_0H03390
uniprot id: H2AYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

1071382:KAFR 0A02820
gene id: 1071382:KAFR_0A02820
uniprot id: H2AMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

1071382:KAFR 0E02060
gene id: 1071382:KAFR_0E02060
uniprot id: H2AVF9
names: Similarity
messages: Belongs to the exportin family.

1071382:KAFR 0A02260
gene id: 1071382:KAFR_0A02260
uniprot id: H2AMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation.
messages: telomere

1071382:KAFR 0F01190
gene id: 1071382:KAFR_0F01190
uniprot id: H2AWG5
names: Similarity
messages: Belongs to the syntaxin family.

1071382:KAFR 0H00740
gene id: 1071382:KAFR_0H00740
uniprot id: H2AYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

1071382:KAFR 0C03950
gene id: 1071382:KAFR_0C03950
uniprot id: H2ASN6
names: Similarity
messages: Belongs to the sulfiredoxin family.

1071382:KAFR 0F02990
gene id: 1071382:KAFR_0F02990
uniprot id: H2AWZ5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071382:KAFR 0I01150
gene id: 1071382:KAFR_0I01150
uniprot id: H2AZU6
names: Similarity
messages: Belongs to the guanylate kinase family.

1071382:KAFR 0C06370
gene id: 1071382:KAFR_0C06370
uniprot id: H2ATD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071382:KAFR 0D00510
gene id: 1071382:KAFR_0D00510
uniprot id: H2ATJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071382:KAFR 0C04520
gene id: 1071382:KAFR_0C04520
uniprot id: H2ASU3
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0C00410
gene id: 1071382:KAFR_0C00410
uniprot id: H2ARN6
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0A06590
gene id: 1071382:KAFR_0A06590
uniprot id: H2ANZ4
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

1071382:KAFR 0C06520
gene id: 1071382:KAFR_0C06520
uniprot id: H2ATE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071382:KAFR 0H00610
gene id: 1071382:KAFR_0H00610
uniprot id: H2AYR4
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071382:KAFR 0B00950
gene id: 1071382:KAFR_0B00950
uniprot id: H2APU3
names: Similarity
messages: Belongs to the cyclin family.

1071382:KAFR 0A01960
gene id: 1071382:KAFR_0A01960
uniprot id: H2AMN4
names: Similarity
messages: Belongs to the ISF1/MBR1 family.

1071382:KAFR 0H02440
gene id: 1071382:KAFR_0H02440
uniprot id: H2AZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071382:KAFR 0D02830
gene id: 1071382:KAFR_0D02830
uniprot id: H2AU81
names: Similarity
messages: Belongs to the PurH family.

1071382:KAFR 0D00620
gene id: 1071382:KAFR_0D00620
uniprot id: H2ATK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1071382:KAFR 0D01900
gene id: 1071382:KAFR_0D01900
uniprot id: H2ATY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

1071382:KAFR 0B03030
gene id: 1071382:KAFR_0B03030
uniprot id: H2AQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

1071382:KAFR 0C05370
gene id: 1071382:KAFR_0C05370
uniprot id: H2AT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

1071382:KAFR 0G01320
gene id: 1071382:KAFR_0G01320
uniprot id: H2AXR6
names: Similarity
messages: Belongs to the VPS52 family.

1071382:KAFR 0D02750
gene id: 1071382:KAFR_0D02750
uniprot id: H2AU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071382:KAFR 0D04100
gene id: 1071382:KAFR_0D04100
uniprot id: H2AUK8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

1071382:KAFR 0J00510
gene id: 1071382:KAFR_0J00510
uniprot id: H2B0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

1071382:KAFR 0B05060
gene id: 1071382:KAFR_0B05060
uniprot id: H2AR02
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1071382:KAFR 0A03290
gene id: 1071382:KAFR_0A03290
uniprot id: H2AN14
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1071382:KAFR 0K01310
gene id: 1071382:KAFR_0K01310
uniprot id: H2B1I5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0L02090
gene id: 1071382:KAFR_0L02090
uniprot id: H2B2H0
names: Subcellular Location Annotation
messages: nucleolus

1071382:KAFR 0A04120
gene id: 1071382:KAFR_0A04120
uniprot id: H2AN97
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0A02980
gene id: 1071382:KAFR_0A02980
uniprot id: H2AMY3
names: Subcellular Location Annotation
messages: Membrane

1071382:KAFR 0C05600
gene id: 1071382:KAFR_0C05600
uniprot id: H2AT51
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L01160
gene id: 1071382:KAFR_0L01160
uniprot id: H2B274
names: Similarity
messages: Belongs to the IMPACT family.

1071382:KAFR 0J00890
gene id: 1071382:KAFR_0J00890
uniprot id: H2B0K7
names: Subcellular Location Annotation
messages: Nucleus

1071382:KAFR 0L00870
gene id: 1071382:KAFR_0L00870
uniprot id: H2B245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

1071382:KAFR 0H01040
gene id: 1071382:KAFR_0H01040
uniprot id: H2AYV8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071382:KAFR 0K00930
gene id: 1071382:KAFR_0K00930
uniprot id: H2B1E9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1071382:KAFR 0I00340
gene id: 1071382:KAFR_0I00340
uniprot id: H2AZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

1071382:KAFR 0C00260
gene id: 1071382:KAFR_0C00260
uniprot id: H2ARM2
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1071382:KAFR 0F02390
gene id: 1071382:KAFR_0F02390
uniprot id: H2AWT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

1071382:KAFR 0C03600
gene id: 1071382:KAFR_0C03600
uniprot id: H2ASK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

1071382:KAFR 0B02730
gene id: 1071382:KAFR_0B02730
uniprot id: H2AQC0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1071382:KAFR 0B01640
gene id: 1071382:KAFR_0B01640
uniprot id: H2AQ13
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

1071382:KAFR 0G02030
gene id: 1071382:KAFR_0G02030
uniprot id: H2AXY7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.

1071382:KAFR 0I02890
gene id: 1071382:KAFR_0I02890
uniprot id: H2B0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

1071382:KAFR 0A02220
gene id: 1071382:KAFR_0A02220
uniprot id: H2AMR0
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

1071382:KAFR 0B04280
gene id: 1071382:KAFR_0B04280
uniprot id: H2AQS4
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071382:KAFR 0A04210
gene id: 1071382:KAFR_0A04210
uniprot id: H2ANA6
names: Similarity
messages: Belongs to the peptidase C19 family.

1071382:KAFR 0F02540
gene id: 1071382:KAFR_0F02540
uniprot id: H2AWV1
names: Similarity
messages: Belongs to the UPP synthase family.

1071382:KAFR 0B04570
gene id: 1071382:KAFR_0B04570
uniprot id: H2AQV4
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

1071382:KAFR 0A04260
gene id: 1071382:KAFR_0A04260
uniprot id: H2ANB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

1071382:KAFR 0F03860
gene id: 1071382:KAFR_0F03860
uniprot id: H2AX82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

1071382:KAFR 0J02160
gene id: 1071382:KAFR_0J02160
uniprot id: H2B0Y0
names: Similarity
messages: Belongs to the LSM12 family.