1071381:TPHA 0J01560
gene id: 1071381:TPHA_0J01560
uniprot id: G8BYN5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

1071381:TPHA 0O01340
gene id: 1071381:TPHA_0O01340
uniprot id: G8C1S4
names: Similarity
messages: Belongs to the cullin family.

1071381:TPHA 0M00860
gene id: 1071381:TPHA_0M00860
uniprot id: G8C0E6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071381:TPHA 0N01700
gene id: 1071381:TPHA_0N01700
uniprot id: G8C1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0A04850
gene id: 1071381:TPHA_0A04850
uniprot id: G8BNT2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1071381:TPHA 0N00710
gene id: 1071381:TPHA_0N00710
uniprot id: G8C124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

1071381:TPHA 0J02810
gene id: 1071381:TPHA_0J02810
uniprot id: G8BZ10
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0N00640
gene id: 1071381:TPHA_0N00640
uniprot id: G8C117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0H01470
gene id: 1071381:TPHA_0H01470
uniprot id: G8BX49
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H00920
gene id: 1071381:TPHA_0H00920
uniprot id: G8BWZ6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1071381:TPHA 0G03440
gene id: 1071381:TPHA_0G03440
uniprot id: G8BWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

1071381:TPHA 0C03690
gene id: 1071381:TPHA_0C03690
uniprot id: G8BQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP2 family.
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0D02850
gene id: 1071381:TPHA_0D02850
uniprot id: G8BSV0
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071381:TPHA 0G03160
gene id: 1071381:TPHA_0G03160
uniprot id: G8BW78
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1071381:TPHA 0B04700
gene id: 1071381:TPHA_0B04700
uniprot id: G8BQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1071381:TPHA 0J02480
gene id: 1071381:TPHA_0J02480
uniprot id: G8BYX6
names: Similarity
messages: Belongs to the CBP3 family.

1071381:TPHA 0E03440
gene id: 1071381:TPHA_0E03440
uniprot id: G8BU56
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P01300
gene id: 1071381:TPHA_0P01300
uniprot id: G8C2B0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

1071381:TPHA 0H01010
gene id: 1071381:TPHA_0H01010
uniprot id: G8BX05
names: Similarity
messages: Belongs to the exportin family.

1071381:TPHA 0D02420
gene id: 1071381:TPHA_0D02420
uniprot id: G8BSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0C02600
gene id: 1071381:TPHA_0C02600
uniprot id: G8BRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B00520
gene id: 1071381:TPHA_0B00520
uniprot id: G8BQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

1071381:TPHA 0B01460
gene id: 1071381:TPHA_0B01460
uniprot id: G8BP88
names: Similarity
messages: Belongs to the actin family.

1071381:TPHA 0K01460
gene id: 1071381:TPHA_0K01460
uniprot id: G8BZF1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

1071381:TPHA 0J00780
gene id: 1071381:TPHA_0J00780
uniprot id: G8BYF9
names: Similarity
messages: Belongs to the eIF2D family.

1071381:TPHA 0A03350
gene id: 1071381:TPHA_0A03350
uniprot id: G8BND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

1071381:TPHA 0K01030
gene id: 1071381:TPHA_0K01030
uniprot id: G8BZA9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071381:TPHA 0E03330
gene id: 1071381:TPHA_0E03330
uniprot id: G8BU45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0P01200
gene id: 1071381:TPHA_0P01200
uniprot id: G8C2A0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071381:TPHA 0B03090
gene id: 1071381:TPHA_0B03090
uniprot id: G8BPQ0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0K01740
gene id: 1071381:TPHA_0K01740
uniprot id: G8BZH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1071381:TPHA 0E01780
gene id: 1071381:TPHA_0E01780
uniprot id: G8BTP3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1071381:TPHA 0B04650
gene id: 1071381:TPHA_0B04650
uniprot id: G8BQ53
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0P00440
gene id: 1071381:TPHA_0P00440
uniprot id: G8C224
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071381:TPHA 0I00670
gene id: 1071381:TPHA_0I00670
uniprot id: G8BXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0D00540
gene id: 1071381:TPHA_0D00540
uniprot id: G8BS77
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

1071381:TPHA 0M01790
gene id: 1071381:TPHA_0M01790
uniprot id: G8C0N9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

1071381:TPHA 0E02800
gene id: 1071381:TPHA_0E02800
uniprot id: G8BTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

1071381:TPHA 0H01420
gene id: 1071381:TPHA_0H01420
uniprot id: G8BX44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0J00950
gene id: 1071381:TPHA_0J00950
uniprot id: G8BYH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

1071381:TPHA 0A03060
gene id: 1071381:TPHA_0A03060
uniprot id: G8BNA6
names: Similarity
messages: Belongs to the biotin--protein ligase family.

1071381:TPHA 0F02520
gene id: 1071381:TPHA_0F02520
uniprot id: G8BUE7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1071381:TPHA 0D02300
gene id: 1071381:TPHA_0D02300
uniprot id: G8BSP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1071381:TPHA 0J00990
gene id: 1071381:TPHA_0J00990
uniprot id: G8BYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection
messages: Cytoplasm

1071381:TPHA 0C00990
gene id: 1071381:TPHA_0C00990
uniprot id: G8BR79
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1071381:TPHA 0D04400
gene id: 1071381:TPHA_0D04400
uniprot id: G8BRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

1071381:TPHA 0E02050
gene id: 1071381:TPHA_0E02050
uniprot id: G8BTR9
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071381:TPHA 0L02270
gene id: 1071381:TPHA_0L02270
uniprot id: G8C0A0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0D01870
gene id: 1071381:TPHA_0D01870
uniprot id: G8BSK5
names: Similarity
messages: Belongs to the ATPase delta chain family.

1071381:TPHA 0H01720
gene id: 1071381:TPHA_0H01720
uniprot id: G8BX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

1071381:TPHA 0N01650
gene id: 1071381:TPHA_0N01650
uniprot id: G8C1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1071381:TPHA 0I02110
gene id: 1071381:TPHA_0I02110
uniprot id: G8BXT7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

1071381:TPHA 0H02830
gene id: 1071381:TPHA_0H02830
uniprot id: G8BWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

1071381:TPHA 0G02080
gene id: 1071381:TPHA_0G02080
uniprot id: G8BVW6
names: Similarity
messages: Belongs to the SIP5 family.

1071381:TPHA 0D03290
gene id: 1071381:TPHA_0D03290
uniprot id: G8BSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1071381:TPHA 0E02810
gene id: 1071381:TPHA_0E02810
uniprot id: G8BTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1071381:TPHA 0A03830
gene id: 1071381:TPHA_0A03830
uniprot id: G8BNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1071381:TPHA 0K01110
gene id: 1071381:TPHA_0K01110
uniprot id: G8BZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1071381:TPHA 0D03030
gene id: 1071381:TPHA_0D03030
uniprot id: G8BSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0C02670
gene id: 1071381:TPHA_0C02670
uniprot id: G8BRP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

1071381:TPHA 0E02040
gene id: 1071381:TPHA_0E02040
uniprot id: G8BTR8
names: Similarity
messages: Belongs to the PIAS family.

1071381:TPHA 0J02500
gene id: 1071381:TPHA_0J02500
uniprot id: G8BYX8
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0E02980
gene id: 1071381:TPHA_0E02980
uniprot id: G8BU10
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1071381:TPHA 0E03980
gene id: 1071381:TPHA_0E03980
uniprot id: G8BUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0C03390
gene id: 1071381:TPHA_0C03390
uniprot id: G8BRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

1071381:TPHA 0B03810
gene id: 1071381:TPHA_0B03810
uniprot id: G8BPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

1071381:TPHA 0A01110
gene id: 1071381:TPHA_0A01110
uniprot id: G8BMR7
names: Similarity
messages: Belongs to the peptidase C14B family.

1071381:TPHA 0D00500
gene id: 1071381:TPHA_0D00500
uniprot id: G8BS73
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

1071381:TPHA 0P00550
gene id: 1071381:TPHA_0P00550
uniprot id: G8C235
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071381:TPHA 0A01780
gene id: 1071381:TPHA_0A01780
uniprot id: G8BMY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0C00660
gene id: 1071381:TPHA_0C00660
uniprot id: G8BR47
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

1071381:TPHA 0B03010
gene id: 1071381:TPHA_0B03010
uniprot id: G8BPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0N00250
gene id: 1071381:TPHA_0N00250
uniprot id: G8C0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

1071381:TPHA 0J02350
gene id: 1071381:TPHA_0J02350
uniprot id: G8BYW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

1071381:TPHA 0D01240
gene id: 1071381:TPHA_0D01240
uniprot id: G8BSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0F01670
gene id: 1071381:TPHA_0F01670
uniprot id: G8BV69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071381:TPHA 0B00500
gene id: 1071381:TPHA_0B00500
uniprot id: G8BQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

1071381:TPHA 0C02320
gene id: 1071381:TPHA_0C02320
uniprot id: G8BRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

1071381:TPHA 0A01330
gene id: 1071381:TPHA_0A01330
uniprot id: G8BMT8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1071381:TPHA 0C01350
gene id: 1071381:TPHA_0C01350
uniprot id: G8BRB5
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

1071381:TPHA 0M00240
gene id: 1071381:TPHA_0M00240
uniprot id: G8C0U1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071381:TPHA 0B02630
gene id: 1071381:TPHA_0B02630
uniprot id: G8BPK5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071381:TPHA 0K02280
gene id: 1071381:TPHA_0K02280
uniprot id: G8BZN0
names: Similarity
messages: Belongs to the FGGY kinase family.

1071381:TPHA 0C04900
gene id: 1071381:TPHA_0C04900
uniprot id: G8BQX6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C02450
gene id: 1071381:TPHA_0C02450
uniprot id: G8BRM2
names: Similarity
messages: Belongs to the peptidase M16 family.

1071381:TPHA 0K01520
gene id: 1071381:TPHA_0K01520
uniprot id: G8BZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

1071381:TPHA 0F03610
gene id: 1071381:TPHA_0F03610
uniprot id: G8BUQ5
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

1071381:TPHA 0I00440
gene id: 1071381:TPHA_0I00440
uniprot id: G8BXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071381:TPHA 0E00630
gene id: 1071381:TPHA_0E00630
uniprot id: G8BTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

1071381:TPHA 0B00940
gene id: 1071381:TPHA_0B00940
uniprot id: G8BQG9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D01920
gene id: 1071381:TPHA_0D01920
uniprot id: G8BSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0K00300
gene id: 1071381:TPHA_0K00300
uniprot id: G8BZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

1071381:TPHA 0H03030
gene id: 1071381:TPHA_0H03030
uniprot id: G8BWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0J00350
gene id: 1071381:TPHA_0J00350
uniprot id: G8BYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0E01840
gene id: 1071381:TPHA_0E01840
uniprot id: G8BTP9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1071381:TPHA 0C02540
gene id: 1071381:TPHA_0C02540
uniprot id: G8BRN1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0K00290
gene id: 1071381:TPHA_0K00290
uniprot id: G8BZ35
names: Similarity
messages: Belongs to the RAD52 family.

1071381:TPHA 0H01440
gene id: 1071381:TPHA_0H01440
uniprot id: G8BX46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0D02200
gene id: 1071381:TPHA_0D02200
uniprot id: G8BSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0B02920
gene id: 1071381:TPHA_0B02920
uniprot id: G8BPN3
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

1071381:TPHA 0N00830
gene id: 1071381:TPHA_0N00830
uniprot id: G8C136
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0K00520
gene id: 1071381:TPHA_0K00520
uniprot id: G8BZ58
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B01110
gene id: 1071381:TPHA_0B01110
uniprot id: G8BQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0B01290
gene id: 1071381:TPHA_0B01290
uniprot id: G8BP71
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071381:TPHA 0A03960
gene id: 1071381:TPHA_0A03960
uniprot id: G8BNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0M01900
gene id: 1071381:TPHA_0M01900
uniprot id: G8C0Q0
names: Similarity
messages: Belongs to the PAT1 family.

1071381:TPHA 0C03300
gene id: 1071381:TPHA_0C03300
uniprot id: G8BRV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

1071381:TPHA 0A02120
gene id: 1071381:TPHA_0A02120
uniprot id: G8BN16
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

1071381:TPHA 0D02120
gene id: 1071381:TPHA_0D02120
uniprot id: G8BSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

1071381:TPHA 0H01900
gene id: 1071381:TPHA_0H01900
uniprot id: G8BWE4
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1071381:TPHA 0J02630
gene id: 1071381:TPHA_0J02630
uniprot id: G8BYZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

1071381:TPHA 0M00870
gene id: 1071381:TPHA_0M00870
uniprot id: G8C0E7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1071381:TPHA 0N00420
gene id: 1071381:TPHA_0N00420
uniprot id: G8C0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

1071381:TPHA 0O01180
gene id: 1071381:TPHA_0O01180
uniprot id: G8C1Q9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0P01510
gene id: 1071381:TPHA_0P01510
uniprot id: G8C2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071381:TPHA 0B02930
gene id: 1071381:TPHA_0B02930
uniprot id: G8BPN4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0D03040
gene id: 1071381:TPHA_0D03040
uniprot id: G8BSW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

1071381:TPHA 0A02560
gene id: 1071381:TPHA_0A02560
uniprot id: G8BN61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0J01800
gene id: 1071381:TPHA_0J01800
uniprot id: G8BYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0B00740
gene id: 1071381:TPHA_0B00740
uniprot id: G8BQE9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071381:TPHA 0A01020
gene id: 1071381:TPHA_0A01020
uniprot id: G8BMQ9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071381:TPHA 0K00560
gene id: 1071381:TPHA_0K00560
uniprot id: G8BZ62
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1071381:TPHA 0C03870
gene id: 1071381:TPHA_0C03870
uniprot id: G8BQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

1071381:TPHA 0G00670
gene id: 1071381:TPHA_0G00670
uniprot id: G8BVH5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1071381:TPHA 0D04570
gene id: 1071381:TPHA_0D04570
uniprot id: G8BS16
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

1071381:TPHA 0G01980
gene id: 1071381:TPHA_0G01980
uniprot id: G8BVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

1071381:TPHA 0P00830
gene id: 1071381:TPHA_0P00830
uniprot id: G8C263
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071381:TPHA 0B03110
gene id: 1071381:TPHA_0B03110
uniprot id: G8BPQ2
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

1071381:TPHA 0B02650
gene id: 1071381:TPHA_0B02650
uniprot id: G8BPK7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1071381:TPHA 0D02310
gene id: 1071381:TPHA_0D02310
uniprot id: G8BSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

1071381:TPHA 0M01190
gene id: 1071381:TPHA_0M01190
uniprot id: G8C0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071381:TPHA 0G01170
gene id: 1071381:TPHA_0G01170
uniprot id: G8BVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

1071381:TPHA 0D03190
gene id: 1071381:TPHA_0D03190
uniprot id: G8BSY4
names: Similarity
messages: Belongs to the taffazin family.

1071381:TPHA 0C03540
gene id: 1071381:TPHA_0C03540
uniprot id: G8BQJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

1071381:TPHA 0I02440
gene id: 1071381:TPHA_0I02440
uniprot id: G8BXW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

1071381:TPHA 0O00290
gene id: 1071381:TPHA_0O00290
uniprot id: G8C1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

1071381:TPHA 0I01350
gene id: 1071381:TPHA_0I01350
uniprot id: G8BXL4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J03050
gene id: 1071381:TPHA_0J03050
uniprot id: G8BY74
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1071381:TPHA 0L01710
gene id: 1071381:TPHA_0L01710
uniprot id: G8C046
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

1071381:TPHA 0A02530
gene id: 1071381:TPHA_0A02530
uniprot id: G8BN58
names: Similarity
messages: Belongs to the syntaxin family.

1071381:TPHA 0F00570
gene id: 1071381:TPHA_0F00570
uniprot id: G8BUW2
names: Similarity
messages: Belongs to the R-transferase family.

1071381:TPHA 0J00500
gene id: 1071381:TPHA_0J00500
uniprot id: G8BYD1
names: Similarity
messages: Belongs to the lysophospholipase family.

1071381:TPHA 0A04110
gene id: 1071381:TPHA_0A04110
uniprot id: G8BNK8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

1071381:TPHA 0A02510
gene id: 1071381:TPHA_0A02510
uniprot id: G8BN56
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0P00490
gene id: 1071381:TPHA_0P00490
uniprot id: G8C229
names: Similarity
messages: Belongs to the PrpD family.

1071381:TPHA 0C03490
gene id: 1071381:TPHA_0C03490
uniprot id: G8BQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0E02310
gene id: 1071381:TPHA_0E02310
uniprot id: G8BTU5
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

1071381:TPHA 0D04100
gene id: 1071381:TPHA_0D04100
uniprot id: G8BT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1071381:TPHA 0O01730
gene id: 1071381:TPHA_0O01730
uniprot id: G8C1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0D02940
gene id: 1071381:TPHA_0D02940
uniprot id: G8BSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1071381:TPHA 0H01400
gene id: 1071381:TPHA_0H01400
uniprot id: G8BX42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0A05090
gene id: 1071381:TPHA_0A05090
uniprot id: G8BNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

1071381:TPHA 0C03650
gene id: 1071381:TPHA_0C03650
uniprot id: G8BQK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

1071381:TPHA 0B04000
gene id: 1071381:TPHA_0B04000
uniprot id: G8BPZ1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D02460
gene id: 1071381:TPHA_0D02460
uniprot id: G8BSR2
names: Similarity
messages: Belongs to the TAF11 family.

1071381:TPHA 0K02290
gene id: 1071381:TPHA_0K02290
uniprot id: G8BZN1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

1071381:TPHA 0J01000
gene id: 1071381:TPHA_0J01000
uniprot id: G8BYI0
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0I01170
gene id: 1071381:TPHA_0I01170
uniprot id: G8BXJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

1071381:TPHA 0O00890
gene id: 1071381:TPHA_0O00890
uniprot id: G8C1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0A04280
gene id: 1071381:TPHA_0A04280
uniprot id: G8BNM4
names: Similarity
messages: Belongs to the PP2C family.

1071381:TPHA 0A03030
gene id: 1071381:TPHA_0A03030
uniprot id: G8BNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

1071381:TPHA 0M02040
gene id: 1071381:TPHA_0M02040
uniprot id: G8C0R3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L01790
gene id: 1071381:TPHA_0L01790
uniprot id: G8C054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1071381:TPHA 0H03040
gene id: 1071381:TPHA_0H03040
uniprot id: G8BWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
messages: Nucleus

1071381:TPHA 0I03150
gene id: 1071381:TPHA_0I03150
uniprot id: G8BY38
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1071381:TPHA 0J02830
gene id: 1071381:TPHA_0J02830
uniprot id: G8BZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0G00900
gene id: 1071381:TPHA_0G00900
uniprot id: G8BVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

1071381:TPHA 0C04450
gene id: 1071381:TPHA_0C04450
uniprot id: G8BQT4
names: Function
names: Similarity
messages: Belongs to the RRT5 family.
messages: May be involved in the modulation of rDNA transcription.

1071381:TPHA 0M01150
gene id: 1071381:TPHA_0M01150
uniprot id: G8C0H5
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1071381:TPHA 0D02360
gene id: 1071381:TPHA_0D02360
uniprot id: G8BSQ2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1071381:TPHA 0L01460
gene id: 1071381:TPHA_0L01460
uniprot id: G8C023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0E00110
gene id: 1071381:TPHA_0E00110
uniprot id: G8BT80
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1071381:TPHA 0L02240
gene id: 1071381:TPHA_0L02240
uniprot id: G8C097
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D03980
gene id: 1071381:TPHA_0D03980
uniprot id: G8BT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F01700
gene id: 1071381:TPHA_0F01700
uniprot id: G8BV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0E02410
gene id: 1071381:TPHA_0E02410
uniprot id: G8BTV5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0G02620
gene id: 1071381:TPHA_0G02620
uniprot id: G8BW21
names: Similarity
messages: Belongs to the TPP enzyme family.

1071381:TPHA 0F02430
gene id: 1071381:TPHA_0F02430
uniprot id: G8BUD8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

1071381:TPHA 0G02530
gene id: 1071381:TPHA_0G02530
uniprot id: G8BW10
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

1071381:TPHA 0B01615
gene id: 1071381:TPHA_0B01615
uniprot id: G8BPA4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1071381:TPHA 0I02720
gene id: 1071381:TPHA_0I02720
uniprot id: G8BXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1071381:TPHA 0A02730
gene id: 1071381:TPHA_0A02730
uniprot id: G8BN77
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0O00950
gene id: 1071381:TPHA_0O00950
uniprot id: G8C1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0E03130
gene id: 1071381:TPHA_0E03130
uniprot id: G8BU25
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1071381:TPHA 0C02940
gene id: 1071381:TPHA_0C02940
uniprot id: G8BRS1
names: Similarity
messages: Belongs to the END3 family.

1071381:TPHA 0C04040
gene id: 1071381:TPHA_0C04040
uniprot id: G8BQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

1071381:TPHA 0B03430
gene id: 1071381:TPHA_0B03430
uniprot id: G8BPT2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0G01610
gene id: 1071381:TPHA_0G01610
uniprot id: G8BVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

1071381:TPHA 0N00620
gene id: 1071381:TPHA_0N00620
uniprot id: G8C115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

1071381:TPHA 0M01400
gene id: 1071381:TPHA_0M01400
uniprot id: G8C0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

1071381:TPHA 0D02800
gene id: 1071381:TPHA_0D02800
uniprot id: G8BSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

1071381:TPHA 0L00670
gene id: 1071381:TPHA_0L00670
uniprot id: G8BZU5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

1071381:TPHA 0G01680
gene id: 1071381:TPHA_0G01680
uniprot id: G8BVS6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1071381:TPHA 0B02190
gene id: 1071381:TPHA_0B02190
uniprot id: G8BPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0G00780
gene id: 1071381:TPHA_0G00780
uniprot id: G8BVI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0N01340
gene id: 1071381:TPHA_0N01340
uniprot id: G8C187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC42 family.
messages: Forms a polymeric layer at the periphery of the spindle pole body (SPB) central plaque which has an essential function during SPB duplication and may facilitate attachment of the SPB to the nuclear membrane.
messages: spindle pole body

1071381:TPHA 0E01970
gene id: 1071381:TPHA_0E01970
uniprot id: G8BTR1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0B03550
gene id: 1071381:TPHA_0B03550
uniprot id: G8BPU4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

1071381:TPHA 0J01190
gene id: 1071381:TPHA_0J01190
uniprot id: G8BYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

1071381:TPHA 0D00970
gene id: 1071381:TPHA_0D00970
uniprot id: G8BSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

1071381:TPHA 0O01130
gene id: 1071381:TPHA_0O01130
uniprot id: G8C1Q4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

1071381:TPHA 0N01780
gene id: 1071381:TPHA_0N01780
uniprot id: G8C1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

1071381:TPHA 0B02850
gene id: 1071381:TPHA_0B02850
uniprot id: G8BPM6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.

1071381:TPHA 0M00400
gene id: 1071381:TPHA_0M00400
uniprot id: G8C0V4
names: Similarity
messages: Belongs to the SF3A2 family.

1071381:TPHA 0E02910
gene id: 1071381:TPHA_0E02910
uniprot id: G8BU03
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071381:TPHA 0B04390
gene id: 1071381:TPHA_0B04390
uniprot id: G8BQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

1071381:TPHA 0E03920
gene id: 1071381:TPHA_0E03920
uniprot id: G8BUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

1071381:TPHA 0B01970
gene id: 1071381:TPHA_0B01970
uniprot id: G8BPD8
names: Similarity
messages: Belongs to the CDC73 family.

1071381:TPHA 0E00940
gene id: 1071381:TPHA_0E00940
uniprot id: G8BTG0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A02330
gene id: 1071381:TPHA_0A02330
uniprot id: G8BN37
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1071381:TPHA 0A04840
gene id: 1071381:TPHA_0A04840
uniprot id: G8BNT1
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1071381:TPHA 0E01830
gene id: 1071381:TPHA_0E01830
uniprot id: G8BTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0F00940
gene id: 1071381:TPHA_0F00940
uniprot id: G8BUZ8
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

1071381:TPHA 0K01190
gene id: 1071381:TPHA_0K01190
uniprot id: G8BZC5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0I01980
gene id: 1071381:TPHA_0I01980
uniprot id: G8BXS4
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

1071381:TPHA 0A05180
gene id: 1071381:TPHA_0A05180
uniprot id: G8BNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA11 family.
messages: Cytoplasm

1071381:TPHA 0F00270
gene id: 1071381:TPHA_0F00270
uniprot id: G8BUT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0I01300
gene id: 1071381:TPHA_0I01300
uniprot id: G8BXK9
names: Similarity
messages: Belongs to the actin family.

1071381:TPHA 0C03410
gene id: 1071381:TPHA_0C03410
uniprot id: G8BRW7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1071381:TPHA 0D03420
gene id: 1071381:TPHA_0D03420
uniprot id: G8BT06
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

1071381:TPHA 0L01120
gene id: 1071381:TPHA_0L01120
uniprot id: G8BZZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

1071381:TPHA 0L01730
gene id: 1071381:TPHA_0L01730
uniprot id: G8C048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

1071381:TPHA 0N01040
gene id: 1071381:TPHA_0N01040
uniprot id: G8C157
names: Similarity
messages: Belongs to the bystin family.

1071381:TPHA 0K00650
gene id: 1071381:TPHA_0K00650
uniprot id: G8BZ71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24 family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

1071381:TPHA 0G03700
gene id: 1071381:TPHA_0G03700
uniprot id: G8BWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071381:TPHA 0B02660
gene id: 1071381:TPHA_0B02660
uniprot id: G8BPK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

1071381:TPHA 0L00610
gene id: 1071381:TPHA_0L00610
uniprot id: G8BZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

1071381:TPHA 0C03020
gene id: 1071381:TPHA_0C03020
uniprot id: G8BRS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1071381:TPHA 0D01660
gene id: 1071381:TPHA_0D01660
uniprot id: G8BSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

1071381:TPHA 0I00150
gene id: 1071381:TPHA_0I00150
uniprot id: G8BX94
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071381:TPHA 0A00580
gene id: 1071381:TPHA_0A00580
uniprot id: G8BML5
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0G01620
gene id: 1071381:TPHA_0G01620
uniprot id: G8BVS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Required for methionine synthesis and maintenance of intact mitochondrial DNA. Involved in telomere maintenance.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

1071381:TPHA 0H02270
gene id: 1071381:TPHA_0H02270
uniprot id: G8BWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

1071381:TPHA 0J02800
gene id: 1071381:TPHA_0J02800
uniprot id: G8BZ09
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

1071381:TPHA 0D01500
gene id: 1071381:TPHA_0D01500
uniprot id: G8BSG9
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

1071381:TPHA 0L02210
gene id: 1071381:TPHA_0L02210
uniprot id: G8C094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

1071381:TPHA 0G00160
gene id: 1071381:TPHA_0G00160
uniprot id: G8BVC9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071381:TPHA 0E02020
gene id: 1071381:TPHA_0E02020
uniprot id: G8BTR6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071381:TPHA 0C04000
gene id: 1071381:TPHA_0C04000
uniprot id: G8BQN8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D02340
gene id: 1071381:TPHA_0D02340
uniprot id: G8BSQ0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0I02950
gene id: 1071381:TPHA_0I02950
uniprot id: G8BY18
names: Similarity
messages: Belongs to the yippee family.

1071381:TPHA 0C04840
gene id: 1071381:TPHA_0C04840
uniprot id: G8BQX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071381:TPHA 0D00480
gene id: 1071381:TPHA_0D00480
uniprot id: G8BS71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

1071381:TPHA 0B01480
gene id: 1071381:TPHA_0B01480
uniprot id: G8BP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

1071381:TPHA 0A04200
gene id: 1071381:TPHA_0A04200
uniprot id: G8BNL7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D04270
gene id: 1071381:TPHA_0D04270
uniprot id: G8BRY6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0H01110
gene id: 1071381:TPHA_0H01110
uniprot id: G8BX15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

1071381:TPHA 0B02900
gene id: 1071381:TPHA_0B02900
uniprot id: G8BPN1
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

1071381:TPHA 0D00810
gene id: 1071381:TPHA_0D00810
uniprot id: G8BSA3
names: Similarity
messages: Belongs to the RRP12 family.

1071381:TPHA 0N00450
gene id: 1071381:TPHA_0N00450
uniprot id: G8C0Z7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

1071381:TPHA 0G02470
gene id: 1071381:TPHA_0G02470
uniprot id: G8BW04
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1071381:TPHA 0G00810
gene id: 1071381:TPHA_0G00810
uniprot id: G8BVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

1071381:TPHA 0P01600
gene id: 1071381:TPHA_0P01600
uniprot id: G8C2E0
names: Similarity
messages: Belongs to the DCP1 family.

1071381:TPHA 0M01990
gene id: 1071381:TPHA_0M01990
uniprot id: G8C0Q9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1071381:TPHA 0I02410
gene id: 1071381:TPHA_0I02410
uniprot id: G8BXW6
names: Similarity
messages: Belongs to the polyprenol kinase family.

1071381:TPHA 0P00710
gene id: 1071381:TPHA_0P00710
uniprot id: G8C251
names: Similarity
messages: Belongs to the YOS1 family.

1071381:TPHA 0I00870
gene id: 1071381:TPHA_0I00870
uniprot id: G8BXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

1071381:TPHA 0O01320
gene id: 1071381:TPHA_0O01320
uniprot id: G8C1S2
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

1071381:TPHA 0E02290
gene id: 1071381:TPHA_0E02290
uniprot id: G8BTU3
names: Similarity
messages: Belongs to the peptidase S9B family.

1071381:TPHA 0A02980
gene id: 1071381:TPHA_0A02980
uniprot id: G8BNA0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1071381:TPHA 0A02500
gene id: 1071381:TPHA_0A02500
uniprot id: G8BN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0D00330
gene id: 1071381:TPHA_0D00330
uniprot id: G8BS56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

1071381:TPHA 0E01630
gene id: 1071381:TPHA_0E01630
uniprot id: G8BTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

1071381:TPHA 0I02170
gene id: 1071381:TPHA_0I02170
uniprot id: G8BXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: actin patch

1071381:TPHA 0A03220
gene id: 1071381:TPHA_0A03220
uniprot id: G8BNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

1071381:TPHA 0H02930
gene id: 1071381:TPHA_0H02930
uniprot id: G8BWP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071381:TPHA 0M01740
gene id: 1071381:TPHA_0M01740
uniprot id: G8C0N4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

1071381:TPHA 0O01230
gene id: 1071381:TPHA_0O01230
uniprot id: G8C1R4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

1071381:TPHA 0E00920
gene id: 1071381:TPHA_0E00920
uniprot id: G8BTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

1071381:TPHA 0E03310
gene id: 1071381:TPHA_0E03310
uniprot id: G8BU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

1071381:TPHA 0D01550
gene id: 1071381:TPHA_0D01550
uniprot id: G8BSH4
names: Similarity
messages: Belongs to the FYV10 family.

1071381:TPHA 0C01890
gene id: 1071381:TPHA_0C01890
uniprot id: G8BRG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1071381:TPHA 0F01390
gene id: 1071381:TPHA_0F01390
uniprot id: G8BV41
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E03880
gene id: 1071381:TPHA_0E03880
uniprot id: G8BU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE28 family.
messages: Involved in kinetochore-microtubule binding and the spindle assembly checkpoint.
messages: Nucleus membrane
messages: kinetochore
messages: spindle pole body

1071381:TPHA 0H02070
gene id: 1071381:TPHA_0H02070
uniprot id: G8BWG0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A01920
gene id: 1071381:TPHA_0A01920
uniprot id: G8BMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1071381:TPHA 0H01770
gene id: 1071381:TPHA_0H01770
uniprot id: G8BX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E01440
gene id: 1071381:TPHA_0E01440
uniprot id: G8BTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0F01040
gene id: 1071381:TPHA_0F01040
uniprot id: G8BV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071381:TPHA 0B04160
gene id: 1071381:TPHA_0B04160
uniprot id: G8BQ05
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1071381:TPHA 0K01480
gene id: 1071381:TPHA_0K01480
uniprot id: G8BZF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071381:TPHA 0I02070
gene id: 1071381:TPHA_0I02070
uniprot id: G8BXT3
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0C00140
gene id: 1071381:TPHA_0C00140
uniprot id: G8BQZ5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1071381:TPHA 0L02250
gene id: 1071381:TPHA_0L02250
uniprot id: G8C098
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

1071381:TPHA 0H01730
gene id: 1071381:TPHA_0H01730
uniprot id: G8BX75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071381:TPHA 0C00280
gene id: 1071381:TPHA_0C00280
uniprot id: G8BR09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1071381:TPHA 0A05570
gene id: 1071381:TPHA_0A05570
uniprot id: G8BP03
names: Similarity
messages: Belongs to the CWC22 family.

1071381:TPHA 0A01340
gene id: 1071381:TPHA_0A01340
uniprot id: G8BMT9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C03560
gene id: 1071381:TPHA_0C03560
uniprot id: G8BQJ6
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

1071381:TPHA 0A01400
gene id: 1071381:TPHA_0A01400
uniprot id: G8BMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

1071381:TPHA 0I01710
gene id: 1071381:TPHA_0I01710
uniprot id: G8BXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0N01660
gene id: 1071381:TPHA_0N01660
uniprot id: G8C1B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

1071381:TPHA 0B04640
gene id: 1071381:TPHA_0B04640
uniprot id: G8BQ52
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

1071381:TPHA 0D01390
gene id: 1071381:TPHA_0D01390
uniprot id: G8BSF9
names: Similarity
messages: Belongs to the NXF family.

1071381:TPHA 0H01610
gene id: 1071381:TPHA_0H01610
uniprot id: G8BX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A02290
gene id: 1071381:TPHA_0A02290
uniprot id: G8BN33
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1071381:TPHA 0B03710
gene id: 1071381:TPHA_0B03710
uniprot id: G8BPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0F02610
gene id: 1071381:TPHA_0F02610
uniprot id: G8BUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

1071381:TPHA 0E01040
gene id: 1071381:TPHA_0E01040
uniprot id: G8BTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

1071381:TPHA 0H01780
gene id: 1071381:TPHA_0H01780
uniprot id: G8BX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

1071381:TPHA 0A03600
gene id: 1071381:TPHA_0A03600
uniprot id: G8BNF8
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

1071381:TPHA 0H00240
gene id: 1071381:TPHA_0H00240
uniprot id: G8BWT1
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0D00410
gene id: 1071381:TPHA_0D00410
uniprot id: G8BS63
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071381:TPHA 0D03690
gene id: 1071381:TPHA_0D03690
uniprot id: G8BT33
names: Similarity
messages: Belongs to the glyoxalase I family.

1071381:TPHA 0H02220
gene id: 1071381:TPHA_0H02220
uniprot id: G8BWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

1071381:TPHA 0D04300
gene id: 1071381:TPHA_0D04300
uniprot id: G8BRY9
names: Similarity
messages: Belongs to the DDI1 family.

1071381:TPHA 0D03080
gene id: 1071381:TPHA_0D03080
uniprot id: G8BSX3
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0H01580
gene id: 1071381:TPHA_0H01580
uniprot id: G8BX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1071381:TPHA 0O00190
gene id: 1071381:TPHA_0O00190
uniprot id: G8C1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

1071381:TPHA 0E01190
gene id: 1071381:TPHA_0E01190
uniprot id: G8BTI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

1071381:TPHA 0O01460
gene id: 1071381:TPHA_0O01460
uniprot id: G8C1T5
names: Subcellular Location Annotation
messages: nuclear pore complex

1071381:TPHA 0N01710
gene id: 1071381:TPHA_0N01710
uniprot id: G8C1C4
names: Similarity
messages: Belongs to the small Tim family.

1071381:TPHA 0N01520
gene id: 1071381:TPHA_0N01520
uniprot id: G8C1A5
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0N01200
gene id: 1071381:TPHA_0N01200
uniprot id: G8C173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

1071381:TPHA 0B04120
gene id: 1071381:TPHA_0B04120
uniprot id: G8BQ01
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071381:TPHA 0E03120
gene id: 1071381:TPHA_0E03120
uniprot id: G8BU24
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J01850
gene id: 1071381:TPHA_0J01850
uniprot id: G8BYR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

1071381:TPHA 0B03720
gene id: 1071381:TPHA_0B03720
uniprot id: G8BPW3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1071381:TPHA 0D03580
gene id: 1071381:TPHA_0D03580
uniprot id: G8BT22
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E01230
gene id: 1071381:TPHA_0E01230
uniprot id: G8BTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0P01320
gene id: 1071381:TPHA_0P01320
uniprot id: G8C2B2
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

1071381:TPHA 0C01070
gene id: 1071381:TPHA_0C01070
uniprot id: G8BR87
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071381:TPHA 0E02350
gene id: 1071381:TPHA_0E02350
uniprot id: G8BTU9
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

1071381:TPHA 0C04820
gene id: 1071381:TPHA_0C04820
uniprot id: G8BQW9
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

1071381:TPHA 0D03240
gene id: 1071381:TPHA_0D03240
uniprot id: G8BSY9
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1071381:TPHA 0D02030
gene id: 1071381:TPHA_0D02030
uniprot id: G8BSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

1071381:TPHA 0P00450
gene id: 1071381:TPHA_0P00450
uniprot id: G8C225
names: Similarity
messages: Belongs to the peptidase M24B family.

1071381:TPHA 0O01990
gene id: 1071381:TPHA_0O01990
uniprot id: G8C1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

1071381:TPHA 0D02550
gene id: 1071381:TPHA_0D02550
uniprot id: G8BSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Nucleus

1071381:TPHA 0M00610
gene id: 1071381:TPHA_0M00610
uniprot id: G8C0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

1071381:TPHA 0H01300
gene id: 1071381:TPHA_0H01300
uniprot id: G8BX33
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0F02880
gene id: 1071381:TPHA_0F02880
uniprot id: G8BUI3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1071381:TPHA 0M00730
gene id: 1071381:TPHA_0M00730
uniprot id: G8C0D3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0D02080
gene id: 1071381:TPHA_0D02080
uniprot id: G8BSM5
names: Similarity
messages: Belongs to the NOP10 family.

1071381:TPHA 0G02070
gene id: 1071381:TPHA_0G02070
uniprot id: G8BVW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1071381:TPHA 0E02570
gene id: 1071381:TPHA_0E02570
uniprot id: G8BTX1
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

1071381:TPHA 0E01130
gene id: 1071381:TPHA_0E01130
uniprot id: G8BTH9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0H01430
gene id: 1071381:TPHA_0H01430
uniprot id: G8BX45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071381:TPHA 0I02810
gene id: 1071381:TPHA_0I02810
uniprot id: G8BY04
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1071381:TPHA 0C00880
gene id: 1071381:TPHA_0C00880
uniprot id: G8BR68
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1071381:TPHA 0P01490
gene id: 1071381:TPHA_0P01490
uniprot id: G8C2C9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

1071381:TPHA 0A00550
gene id: 1071381:TPHA_0A00550
uniprot id: G8BML2
names: Similarity
messages: Belongs to the MON2 family.

1071381:TPHA 0D00770
gene id: 1071381:TPHA_0D00770
uniprot id: G8BS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

1071381:TPHA 0B03820
gene id: 1071381:TPHA_0B03820
uniprot id: G8BPX3
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1071381:TPHA 0G02460
gene id: 1071381:TPHA_0G02460
uniprot id: G8BW03
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

1071381:TPHA 0L00910
gene id: 1071381:TPHA_0L00910
uniprot id: G8BZX0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071381:TPHA 0A05640
gene id: 1071381:TPHA_0A05640
uniprot id: G8BP10
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

1071381:TPHA 0I00790
gene id: 1071381:TPHA_0I00790
uniprot id: G8BXF7
names: Similarity
messages: Belongs to the phospholipase D family.

1071381:TPHA 0H00350
gene id: 1071381:TPHA_0H00350
uniprot id: G8BWU1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

1071381:TPHA 0F00420
gene id: 1071381:TPHA_0F00420
uniprot id: G8BUU7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071381:TPHA 0O01000
gene id: 1071381:TPHA_0O01000
uniprot id: G8C1P1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C03580
gene id: 1071381:TPHA_0C03580
uniprot id: G8BQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0B01620
gene id: 1071381:TPHA_0B01620
uniprot id: G8BPA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071381:TPHA 0A05380
gene id: 1071381:TPHA_0A05380
uniprot id: G8BNY4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0M00260
gene id: 1071381:TPHA_0M00260
uniprot id: G8C0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

1071381:TPHA 0L01010
gene id: 1071381:TPHA_0L01010
uniprot id: G8BZY0
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

1071381:TPHA 0C05000
gene id: 1071381:TPHA_0C05000
uniprot id: G8BQY6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C02720
gene id: 1071381:TPHA_0C02720
uniprot id: G8BRP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1071381:TPHA 0A04600
gene id: 1071381:TPHA_0A04600
uniprot id: G8BNQ5
names: Function
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

1071381:TPHA 0G00600
gene id: 1071381:TPHA_0G00600
uniprot id: G8BVG8
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

1071381:TPHA 0D03780
gene id: 1071381:TPHA_0D03780
uniprot id: G8BT40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

1071381:TPHA 0C04210
gene id: 1071381:TPHA_0C04210
uniprot id: G8BQQ9
names: Similarity
messages: Belongs to the PDCD5 family.

1071381:TPHA 0G02350
gene id: 1071381:TPHA_0G02350
uniprot id: G8BVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

1071381:TPHA 0E03970
gene id: 1071381:TPHA_0E03970
uniprot id: G8BUA8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1071381:TPHA 0M02070
gene id: 1071381:TPHA_0M02070
uniprot id: G8C0R6
names: Similarity
messages: Belongs to the TRM112 family.

1071381:TPHA 0F01750
gene id: 1071381:TPHA_0F01750
uniprot id: G8BV77
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071381:TPHA 0E02000
gene id: 1071381:TPHA_0E02000
uniprot id: G8BTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

1071381:TPHA 0B04710
gene id: 1071381:TPHA_0B04710
uniprot id: G8BQ59
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

1071381:TPHA 0A04550
gene id: 1071381:TPHA_0A04550
uniprot id: G8BNQ0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F03040
gene id: 1071381:TPHA_0F03040
uniprot id: G8BUJ9
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

1071381:TPHA 0B00790
gene id: 1071381:TPHA_0B00790
uniprot id: G8BQF4
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

1071381:TPHA 0C02440
gene id: 1071381:TPHA_0C02440
uniprot id: G8BRM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0D03350
gene id: 1071381:TPHA_0D03350
uniprot id: G8BT00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071381:TPHA 0B01160
gene id: 1071381:TPHA_0B01160
uniprot id: G8BP57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

1071381:TPHA 0D02620
gene id: 1071381:TPHA_0D02620
uniprot id: G8BSS8
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071381:TPHA 0D02380
gene id: 1071381:TPHA_0D02380
uniprot id: G8BSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0C00300
gene id: 1071381:TPHA_0C00300
uniprot id: G8BR11
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0M01390
gene id: 1071381:TPHA_0M01390
uniprot id: G8C0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

1071381:TPHA 0D02480
gene id: 1071381:TPHA_0D02480
uniprot id: G8BSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI19 family.
messages: Component of the phosphatidylinositol N-acetylglucosaminyltransferase (GPI-GlcNAc transferase) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

1071381:TPHA 0E01270
gene id: 1071381:TPHA_0E01270
uniprot id: G8BTJ4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0L01200
gene id: 1071381:TPHA_0L01200
uniprot id: G8BZZ9
names: Similarity
messages: Belongs to the RRM CWC2 family.

1071381:TPHA 0H02760
gene id: 1071381:TPHA_0H02760
uniprot id: G8BWM8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

1071381:TPHA 0K00980
gene id: 1071381:TPHA_0K00980
uniprot id: G8BZA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071381:TPHA 0K01500
gene id: 1071381:TPHA_0K01500
uniprot id: G8BZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

1071381:TPHA 0P01280
gene id: 1071381:TPHA_0P01280
uniprot id: G8C2A8
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

1071381:TPHA 0C01940
gene id: 1071381:TPHA_0C01940
uniprot id: G8BRH3
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

1071381:TPHA 0L00230
gene id: 1071381:TPHA_0L00230
uniprot id: G8BZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Nucleus

1071381:TPHA 0E00600
gene id: 1071381:TPHA_0E00600
uniprot id: G8BTC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071381:TPHA 0B04570
gene id: 1071381:TPHA_0B04570
uniprot id: G8BQ45
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J02030
gene id: 1071381:TPHA_0J02030
uniprot id: G8BYT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1071381:TPHA 0F01650
gene id: 1071381:TPHA_0F01650
uniprot id: G8BV67
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0J02790
gene id: 1071381:TPHA_0J02790
uniprot id: G8BZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

1071381:TPHA 0B02610
gene id: 1071381:TPHA_0B02610
uniprot id: G8BPK3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1071381:TPHA 0G01270
gene id: 1071381:TPHA_0G01270
uniprot id: G8BVN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

1071381:TPHA 0C01590
gene id: 1071381:TPHA_0C01590
uniprot id: G8BRD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071381:TPHA 0J01810
gene id: 1071381:TPHA_0J01810
uniprot id: G8BYR0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A02400
gene id: 1071381:TPHA_0A02400
uniprot id: G8BNE5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071381:TPHA 0G00390
gene id: 1071381:TPHA_0G00390
uniprot id: G8BVE7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P01560
gene id: 1071381:TPHA_0P01560
uniprot id: G8C2D6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071381:TPHA 0I00660
gene id: 1071381:TPHA_0I00660
uniprot id: G8BXE4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A02700
gene id: 1071381:TPHA_0A02700
uniprot id: G8BN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

1071381:TPHA 0G02873
gene id: 1071381:TPHA_0G02873
uniprot id: G8BW48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE2 family.
messages: Nucleus

1071381:TPHA 0E01200
gene id: 1071381:TPHA_0E01200
uniprot id: G8BTI7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0A04060
gene id: 1071381:TPHA_0A04060
uniprot id: G8BNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1071381:TPHA 0B03490
gene id: 1071381:TPHA_0B03490
uniprot id: G8BPT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0P01010
gene id: 1071381:TPHA_0P01010
uniprot id: G8C281
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0D02740
gene id: 1071381:TPHA_0D02740
uniprot id: G8BST9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1071381:TPHA 0K01890
gene id: 1071381:TPHA_0K01890
uniprot id: G8BZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0I00810
gene id: 1071381:TPHA_0I00810
uniprot id: G8BXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071381:TPHA 0I00500
gene id: 1071381:TPHA_0I00500
uniprot id: G8BXC8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1071381:TPHA 0J00480
gene id: 1071381:TPHA_0J00480
uniprot id: G8BYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

1071381:TPHA 0A01490
gene id: 1071381:TPHA_0A01490
uniprot id: G8BMV4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0D01250
gene id: 1071381:TPHA_0D01250
uniprot id: G8BSE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0J01750
gene id: 1071381:TPHA_0J01750
uniprot id: G8BYQ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0E03360
gene id: 1071381:TPHA_0E03360
uniprot id: G8BU48
names: Similarity
messages: Belongs to the LST4 family.

1071381:TPHA 0H02010
gene id: 1071381:TPHA_0H02010
uniprot id: G8BWF4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

1071381:TPHA 0F00400
gene id: 1071381:TPHA_0F00400
uniprot id: G8BUU5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071381:TPHA 0A04510
gene id: 1071381:TPHA_0A04510
uniprot id: G8BNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

1071381:TPHA 0C02190
gene id: 1071381:TPHA_0C02190
uniprot id: G8BRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

1071381:TPHA 0E03160
gene id: 1071381:TPHA_0E03160
uniprot id: G8BU28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

1071381:TPHA 0L00700
gene id: 1071381:TPHA_0L00700
uniprot id: G8BZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0G01030
gene id: 1071381:TPHA_0G01030
uniprot id: G8BVL1
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1071381:TPHA 0E01390
gene id: 1071381:TPHA_0E01390
uniprot id: G8BTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

1071381:TPHA 0F01600
gene id: 1071381:TPHA_0F01600
uniprot id: G8BV62
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1071381:TPHA 0P00230
gene id: 1071381:TPHA_0P00230
uniprot id: G8C203
names: Similarity
messages: Belongs to the TMCO4 family.

1071381:TPHA 0A05470
gene id: 1071381:TPHA_0A05470
uniprot id: G8BNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0D01670
gene id: 1071381:TPHA_0D01670
uniprot id: G8BSI6
names: Similarity
messages: Belongs to the RCAN family.

1071381:TPHA 0P01810
gene id: 1071381:TPHA_0P01810
uniprot id: G8C2G0
names: Similarity
messages: Belongs to the NARF family.

1071381:TPHA 0F01640
gene id: 1071381:TPHA_0F01640
uniprot id: G8BV66
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0G02300
gene id: 1071381:TPHA_0G02300
uniprot id: G8BVY8
names: Similarity
messages: Belongs to the PurH family.

1071381:TPHA 0I02960
gene id: 1071381:TPHA_0I02960
uniprot id: G8BY19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

1071381:TPHA 0I01750
gene id: 1071381:TPHA_0I01750
uniprot id: G8BXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0P01050
gene id: 1071381:TPHA_0P01050
uniprot id: G8C285
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

1071381:TPHA 0A03660
gene id: 1071381:TPHA_0A03660
uniprot id: G8BNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0J01340
gene id: 1071381:TPHA_0J01340
uniprot id: G8BYL4
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071381:TPHA 0N00790
gene id: 1071381:TPHA_0N00790
uniprot id: G8C132
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

1071381:TPHA 0F01120
gene id: 1071381:TPHA_0F01120
uniprot id: G8BV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1071381:TPHA 0N01910
gene id: 1071381:TPHA_0N01910
uniprot id: G8C1E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0E03320
gene id: 1071381:TPHA_0E03320
uniprot id: G8BU44
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1071381:TPHA 0B03380
gene id: 1071381:TPHA_0B03380
uniprot id: G8BPS8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1071381:TPHA 0A01580
gene id: 1071381:TPHA_0A01580
uniprot id: G8BMW3
names: Similarity
messages: Belongs to the peptidase A1 family.

1071381:TPHA 0I01220
gene id: 1071381:TPHA_0I01220
uniprot id: G8BXK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1071381:TPHA 0K00530
gene id: 1071381:TPHA_0K00530
uniprot id: G8BZ59
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1071381:TPHA 0F00320
gene id: 1071381:TPHA_0F00320
uniprot id: G8BUT7
names: Similarity
messages: Belongs to the peptidase M24B family.

1071381:TPHA 0G00480
gene id: 1071381:TPHA_0G00480
uniprot id: G8BVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

1071381:TPHA 0D01890
gene id: 1071381:TPHA_0D01890
uniprot id: G8BSK7
names: Similarity
messages: Belongs to the PIH1 family.

1071381:TPHA 0A00440
gene id: 1071381:TPHA_0A00440
uniprot id: G8BMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

1071381:TPHA 0G01770
gene id: 1071381:TPHA_0G01770
uniprot id: G8BVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B01800
gene id: 1071381:TPHA_0B01800
uniprot id: G8BPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0J02280
gene id: 1071381:TPHA_0J02280
uniprot id: G8BYV6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B04900
gene id: 1071381:TPHA_0B04900
uniprot id: G8BQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

1071381:TPHA 0N00780
gene id: 1071381:TPHA_0N00780
uniprot id: G8C131
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071381:TPHA 0A01420
gene id: 1071381:TPHA_0A01420
uniprot id: G8BMU7
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1071381:TPHA 0I02150
gene id: 1071381:TPHA_0I02150
uniprot id: G8BXU1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C00610
gene id: 1071381:TPHA_0C00610
uniprot id: G8BR42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

1071381:TPHA 0C04440
gene id: 1071381:TPHA_0C04440
uniprot id: G8BQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

1071381:TPHA 0F01940
gene id: 1071381:TPHA_0F01940
uniprot id: G8BV94
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071381:TPHA 0C00110
gene id: 1071381:TPHA_0C00110
uniprot id: G8BQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

1071381:TPHA 0C01820
gene id: 1071381:TPHA_0C01820
uniprot id: G8BRG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1071381:TPHA 0M00450
gene id: 1071381:TPHA_0M00450
uniprot id: G8C0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

1071381:TPHA 0H00270
gene id: 1071381:TPHA_0H00270
uniprot id: G8BWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0B04480
gene id: 1071381:TPHA_0B04480
uniprot id: G8BQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0E01470
gene id: 1071381:TPHA_0E01470
uniprot id: G8BTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1071381:TPHA 0A00720
gene id: 1071381:TPHA_0A00720
uniprot id: G8BMM9
names: Subunit
messages: Monomer.

1071381:TPHA 0A02240
gene id: 1071381:TPHA_0A02240
uniprot id: G8BN28
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1071381:TPHA 0B01750
gene id: 1071381:TPHA_0B01750
uniprot id: G8BPB7
names: Similarity
messages: Belongs to the helicase family.

1071381:TPHA 0H02590
gene id: 1071381:TPHA_0H02590
uniprot id: G8BWL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1071381:TPHA 0D00990
gene id: 1071381:TPHA_0D00990
uniprot id: G8BSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

1071381:TPHA 0C01120
gene id: 1071381:TPHA_0C01120
uniprot id: G8BR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071381:TPHA 0D03680
gene id: 1071381:TPHA_0D03680
uniprot id: G8BT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0I02450
gene id: 1071381:TPHA_0I02450
uniprot id: G8BXX0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E01520
gene id: 1071381:TPHA_0E01520
uniprot id: G8BTL8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1071381:TPHA 0F02480
gene id: 1071381:TPHA_0F02480
uniprot id: G8BUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0K00630
gene id: 1071381:TPHA_0K00630
uniprot id: G8BZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0L01220
gene id: 1071381:TPHA_0L01220
uniprot id: G8C001
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

1071381:TPHA 0C01700
gene id: 1071381:TPHA_0C01700
uniprot id: G8BRF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

1071381:TPHA 0I01920
gene id: 1071381:TPHA_0I01920
uniprot id: G8BXR8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1071381:TPHA 0P00850
gene id: 1071381:TPHA_0P00850
uniprot id: G8C265
names: Similarity
messages: Belongs to the cullin family.

1071381:TPHA 0I00380
gene id: 1071381:TPHA_0I00380
uniprot id: G8BXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0I01180
gene id: 1071381:TPHA_0I01180
uniprot id: G8BXJ6
names: Similarity
messages: Belongs to the peptidase M20A family.

1071381:TPHA 0J02735
gene id: 1071381:TPHA_0J02735
uniprot id: G8BTL8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1071381:TPHA 0E03380
gene id: 1071381:TPHA_0E03380
uniprot id: G8BU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

1071381:TPHA 0B00280
gene id: 1071381:TPHA_0B00280
uniprot id: G8BQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

1071381:TPHA 0A06010
gene id: 1071381:TPHA_0A06010
uniprot id: G8BP47
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071381:TPHA 0F01420
gene id: 1071381:TPHA_0F01420
uniprot id: G8BV44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1071381:TPHA 0A03000
gene id: 1071381:TPHA_0A03000
uniprot id: G8BNA1
names: Similarity
messages: Belongs to the dynein heavy chain family.

1071381:TPHA 0M01450
gene id: 1071381:TPHA_0M01450
uniprot id: G8C0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

1071381:TPHA 0K00900
gene id: 1071381:TPHA_0K00900
uniprot id: G8BZ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0E02740
gene id: 1071381:TPHA_0E02740
uniprot id: G8BTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071381:TPHA 0F01790
gene id: 1071381:TPHA_0F01790
uniprot id: G8BV81
names: Similarity
messages: Belongs to the cytochrome b5 family.

1071381:TPHA 0C03780
gene id: 1071381:TPHA_0C03780
uniprot id: G8BQL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

1071381:TPHA 0D03800
gene id: 1071381:TPHA_0D03800
uniprot id: G8BT42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

1071381:TPHA 0D01070
gene id: 1071381:TPHA_0D01070
uniprot id: G8BSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

1071381:TPHA 0G03070
gene id: 1071381:TPHA_0G03070
uniprot id: G8BW70
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

1071381:TPHA 0G02890
gene id: 1071381:TPHA_0G02890
uniprot id: G8BW52
names: Function
names: Similarity
messages: Belongs to the SPG4 family.
messages: Stationary phase-essential protein not required for growth on nonfermentable carbon sources.

1071381:TPHA 0E02620
gene id: 1071381:TPHA_0E02620
uniprot id: G8BTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1071381:TPHA 0H00710
gene id: 1071381:TPHA_0H00710
uniprot id: G8BWX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

1071381:TPHA 0C03980
gene id: 1071381:TPHA_0C03980
uniprot id: G8BQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1071381:TPHA 0J00520
gene id: 1071381:TPHA_0J00520
uniprot id: G8BYD3
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

1071381:TPHA 0N00680
gene id: 1071381:TPHA_0N00680
uniprot id: G8C121
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

1071381:TPHA 0M00690
gene id: 1071381:TPHA_0M00690
uniprot id: G8C0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0F03210
gene id: 1071381:TPHA_0F03210
uniprot id: G8BUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

1071381:TPHA 0H00510
gene id: 1071381:TPHA_0H00510
uniprot id: G8BWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

1071381:TPHA 0A01310
gene id: 1071381:TPHA_0A01310
uniprot id: G8BMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071381:TPHA 0B04230
gene id: 1071381:TPHA_0B04230
uniprot id: G8BQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

1071381:TPHA 0A02170
gene id: 1071381:TPHA_0A02170
uniprot id: G8BN21
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1071381:TPHA 0F01340
gene id: 1071381:TPHA_0F01340
uniprot id: G8BV37
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E01210
gene id: 1071381:TPHA_0E01210
uniprot id: G8BTI8
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

1071381:TPHA 0A00160
gene id: 1071381:TPHA_0A00160
uniprot id: G8BMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

1071381:TPHA 0B04580
gene id: 1071381:TPHA_0B04580
uniprot id: G8BQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

1071381:TPHA 0M00830
gene id: 1071381:TPHA_0M00830
uniprot id: G8C0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

1071381:TPHA 0H02750
gene id: 1071381:TPHA_0H02750
uniprot id: G8BWM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

1071381:TPHA 0G00650
gene id: 1071381:TPHA_0G00650
uniprot id: G8BVH3
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

1071381:TPHA 0G02760
gene id: 1071381:TPHA_0G02760
uniprot id: G8BW36
names: Similarity
messages: Belongs to the PurH family.

1071381:TPHA 0C01140
gene id: 1071381:TPHA_0C01140
uniprot id: G8BR94
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

1071381:TPHA 0H01600
gene id: 1071381:TPHA_0H01600
uniprot id: G8BX62
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0K01960
gene id: 1071381:TPHA_0K01960
uniprot id: G8BZK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1071381:TPHA 0E03300
gene id: 1071381:TPHA_0E03300
uniprot id: G8BU42
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0D01800
gene id: 1071381:TPHA_0D01800
uniprot id: G8BSJ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071381:TPHA 0H02210
gene id: 1071381:TPHA_0H02210
uniprot id: G8BWH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0C03290
gene id: 1071381:TPHA_0C03290
uniprot id: G8BRV5
names: Similarity
messages: Belongs to the SHQ1 family.

1071381:TPHA 0P00610
gene id: 1071381:TPHA_0P00610
uniprot id: G8C241
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0H01940
gene id: 1071381:TPHA_0H01940
uniprot id: G8BWE8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E01250
gene id: 1071381:TPHA_0E01250
uniprot id: G8BTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

1071381:TPHA 0F01330
gene id: 1071381:TPHA_0F01330
uniprot id: G8BV36
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

1071381:TPHA 0I03220
gene id: 1071381:TPHA_0I03220
uniprot id: G8BY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

1071381:TPHA 0A04970
gene id: 1071381:TPHA_0A04970
uniprot id: G8BNU4
names: Similarity
messages: Belongs to the exportin family.

1071381:TPHA 0H01270
gene id: 1071381:TPHA_0H01270
uniprot id: G8BX31
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.
messages: The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.
messages: The capsid protein forms a homotrimer, from which the VLPs are assembled. The protease is a homodimer, whose active site consists of two apposed aspartic acid residues.

1071381:TPHA 0A03020
gene id: 1071381:TPHA_0A03020
uniprot id: G8BNA2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F00970
gene id: 1071381:TPHA_0F00970
uniprot id: G8BV01
names: Similarity
messages: Belongs to the CWC22 family.

1071381:TPHA 0G03730
gene id: 1071381:TPHA_0G03730
uniprot id: G8BWD5
names: Similarity
messages: Belongs to the hexokinase family.

1071381:TPHA 0N01250
gene id: 1071381:TPHA_0N01250
uniprot id: G8C178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0M01360
gene id: 1071381:TPHA_0M01360
uniprot id: G8C0J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

1071381:TPHA 0A03100
gene id: 1071381:TPHA_0A03100
uniprot id: G8BNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0F00770
gene id: 1071381:TPHA_0F00770
uniprot id: G8BUY1
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

1071381:TPHA 0D00530
gene id: 1071381:TPHA_0D00530
uniprot id: G8BS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1071381:TPHA 0D00800
gene id: 1071381:TPHA_0D00800
uniprot id: G8BSA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1071381:TPHA 0I01330
gene id: 1071381:TPHA_0I01330
uniprot id: G8BXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071381:TPHA 0K01600
gene id: 1071381:TPHA_0K01600
uniprot id: G8BZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0C04050
gene id: 1071381:TPHA_0C04050
uniprot id: G8BQP3
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

1071381:TPHA 0C04800
gene id: 1071381:TPHA_0C04800
uniprot id: G8BQW7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1071381:TPHA 0J00160
gene id: 1071381:TPHA_0J00160
uniprot id: G8BY98
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G00530
gene id: 1071381:TPHA_0G00530
uniprot id: G8BVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

1071381:TPHA 0G03560
gene id: 1071381:TPHA_0G03560
uniprot id: G8BWB8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0I00390
gene id: 1071381:TPHA_0I00390
uniprot id: G8BXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1071381:TPHA 0P01020
gene id: 1071381:TPHA_0P01020
uniprot id: G8C282
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1071381:TPHA 0D04120
gene id: 1071381:TPHA_0D04120
uniprot id: G8BT74
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L01400
gene id: 1071381:TPHA_0L01400
uniprot id: G8C017
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0F03130
gene id: 1071381:TPHA_0F03130
uniprot id: G8BUK8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1071381:TPHA 0L01080
gene id: 1071381:TPHA_0L01080
uniprot id: G8BZY7
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0J01250
gene id: 1071381:TPHA_0J01250
uniprot id: G8BYK5
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1071381:TPHA 0F01030
gene id: 1071381:TPHA_0F01030
uniprot id: G8BV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071381:TPHA 0D04560
gene id: 1071381:TPHA_0D04560
uniprot id: G8BS15
names: Similarity
messages: Belongs to the epsin family.

1071381:TPHA 0O00420
gene id: 1071381:TPHA_0O00420
uniprot id: G8C1I5
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

1071381:TPHA 0E03020
gene id: 1071381:TPHA_0E03020
uniprot id: G8BU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.

1071381:TPHA 0J00270
gene id: 1071381:TPHA_0J00270
uniprot id: G8BYA9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

1071381:TPHA 0E00520
gene id: 1071381:TPHA_0E00520
uniprot id: G8BTB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

1071381:TPHA 0G00690
gene id: 1071381:TPHA_0G00690
uniprot id: G8BVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

1071381:TPHA 0D04210
gene id: 1071381:TPHA_0D04210
uniprot id: G8BRY0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B02960
gene id: 1071381:TPHA_0B02960
uniprot id: G8BPN7
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071381:TPHA 0F02450
gene id: 1071381:TPHA_0F02450
uniprot id: G8BUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

1071381:TPHA 0F02950
gene id: 1071381:TPHA_0F02950
uniprot id: G8BUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E04055
gene id: 1071381:TPHA_0E04055
uniprot id: G8BUB5
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J01270
gene id: 1071381:TPHA_0J01270
uniprot id: G8BYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

1071381:TPHA 0L00730
gene id: 1071381:TPHA_0L00730
uniprot id: G8BZV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

1071381:TPHA 0L01100
gene id: 1071381:TPHA_0L01100
uniprot id: G8BZY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0J01330
gene id: 1071381:TPHA_0J01330
uniprot id: G8BYL3
names: Similarity
messages: Belongs to the UPF0538 family.

1071381:TPHA 0E03200
gene id: 1071381:TPHA_0E03200
uniprot id: G8BU32
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00600
gene id: 1071381:TPHA_0L00600
uniprot id: G8BZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

1071381:TPHA 0P00480
gene id: 1071381:TPHA_0P00480
uniprot id: G8C228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

1071381:TPHA 0J02930
gene id: 1071381:TPHA_0J02930
uniprot id: G8BY63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

1071381:TPHA 0G03650
gene id: 1071381:TPHA_0G03650
uniprot id: G8BWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1071381:TPHA 0B03580
gene id: 1071381:TPHA_0B03580
uniprot id: G8BPU7
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

1071381:TPHA 0D00340
gene id: 1071381:TPHA_0D00340
uniprot id: G8BS57
names: Similarity
messages: Belongs to the TMCO4 family.

1071381:TPHA 0M00410
gene id: 1071381:TPHA_0M00410
uniprot id: G8C0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: kinetochore

1071381:TPHA 0J03070
gene id: 1071381:TPHA_0J03070
uniprot id: G8BY76
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071381:TPHA 0F00500
gene id: 1071381:TPHA_0F00500
uniprot id: G8BUV5
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0D04140
gene id: 1071381:TPHA_0D04140
uniprot id: G8BT76
names: Subcellular Location Annotation
messages: Nucleus membrane

1071381:TPHA 0M00390
gene id: 1071381:TPHA_0M00390
uniprot id: G8C0V3
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071381:TPHA 0A03890
gene id: 1071381:TPHA_0A03890
uniprot id: G8BNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

1071381:TPHA 0E03150
gene id: 1071381:TPHA_0E03150
uniprot id: G8BU27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0H03010
gene id: 1071381:TPHA_0H03010
uniprot id: G8BWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071381:TPHA 0G03620
gene id: 1071381:TPHA_0G03620
uniprot id: G8BWC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1071381:TPHA 0E01960
gene id: 1071381:TPHA_0E01960
uniprot id: G8BTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1071381:TPHA 0H02600
gene id: 1071381:TPHA_0H02600
uniprot id: G8BWL2
names: Function
names: Similarity
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.

1071381:TPHA 0D03140
gene id: 1071381:TPHA_0D03140
uniprot id: G8BSX9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J02980
gene id: 1071381:TPHA_0J02980
uniprot id: G8BY67
names: Similarity
messages: Belongs to the PIAS family.

1071381:TPHA 0E01550
gene id: 1071381:TPHA_0E01550
uniprot id: G8BTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071381:TPHA 0D02980
gene id: 1071381:TPHA_0D02980
uniprot id: G8BSW3
names: Similarity
messages: Belongs to the TEL2 family.

1071381:TPHA 0E01070
gene id: 1071381:TPHA_0E01070
uniprot id: G8BTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0G03600
gene id: 1071381:TPHA_0G03600
uniprot id: G8BWC2
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

1071381:TPHA 0A04270
gene id: 1071381:TPHA_0A04270
uniprot id: G8BNM3
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0J00630
gene id: 1071381:TPHA_0J00630
uniprot id: G8BYE4
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071381:TPHA 0A00350
gene id: 1071381:TPHA_0A00350
uniprot id: G8BMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071381:TPHA 0M00570
gene id: 1071381:TPHA_0M00570
uniprot id: G8C0B7
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1071381:TPHA 0N01060
gene id: 1071381:TPHA_0N01060
uniprot id: G8C159
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071381:TPHA 0I01460
gene id: 1071381:TPHA_0I01460
uniprot id: G8BXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

1071381:TPHA 0D00370
gene id: 1071381:TPHA_0D00370
uniprot id: G8BS60
names: Similarity
messages: Belongs to the oligoribonuclease family.

1071381:TPHA 0K01870
gene id: 1071381:TPHA_0K01870
uniprot id: G8BZJ1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C04030
gene id: 1071381:TPHA_0C04030
uniprot id: G8BQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1071381:TPHA 0J01960
gene id: 1071381:TPHA_0J01960
uniprot id: G8BYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

1071381:TPHA 0G00420
gene id: 1071381:TPHA_0G00420
uniprot id: G8BVF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

1071381:TPHA 0E01600
gene id: 1071381:TPHA_0E01600
uniprot id: G8BTM5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071381:TPHA 0J01440
gene id: 1071381:TPHA_0J01440
uniprot id: G8BYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

1071381:TPHA 0O01050
gene id: 1071381:TPHA_0O01050
uniprot id: G8C1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071381:TPHA 0H00580
gene id: 1071381:TPHA_0H00580
uniprot id: G8BWW4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A03440
gene id: 1071381:TPHA_0A03440
uniprot id: G8BNE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

1071381:TPHA 0A03110
gene id: 1071381:TPHA_0A03110
uniprot id: G8BNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0D00260
gene id: 1071381:TPHA_0D00260
uniprot id: G8BS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0D01610
gene id: 1071381:TPHA_0D01610
uniprot id: G8BSI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

1071381:TPHA 0B01350
gene id: 1071381:TPHA_0B01350
uniprot id: G8BP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F03280
gene id: 1071381:TPHA_0F03280
uniprot id: G8BUM3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

1071381:TPHA 0P01250
gene id: 1071381:TPHA_0P01250
uniprot id: G8C2A5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F02940
gene id: 1071381:TPHA_0F02940
uniprot id: G8BUI9
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

1071381:TPHA 0D00910
gene id: 1071381:TPHA_0D00910
uniprot id: G8BSB1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0F01610
gene id: 1071381:TPHA_0F01610
uniprot id: G8BV63
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

1071381:TPHA 0D01150
gene id: 1071381:TPHA_0D01150
uniprot id: G8BSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071381:TPHA 0G01160
gene id: 1071381:TPHA_0G01160
uniprot id: G8BVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071381:TPHA 0E00210
gene id: 1071381:TPHA_0E00210
uniprot id: G8BT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

1071381:TPHA 0K00510
gene id: 1071381:TPHA_0K00510
uniprot id: G8BZ57
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

1071381:TPHA 0K01880
gene id: 1071381:TPHA_0K01880
uniprot id: G8BZJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0G03770
gene id: 1071381:TPHA_0G03770
uniprot id: G8BWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0C01790
gene id: 1071381:TPHA_0C01790
uniprot id: G8BRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

1071381:TPHA 0C02260
gene id: 1071381:TPHA_0C02260
uniprot id: G8BRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0A05230
gene id: 1071381:TPHA_0A05230
uniprot id: G8BNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

1071381:TPHA 0K02060
gene id: 1071381:TPHA_0K02060
uniprot id: G8BZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0N00610
gene id: 1071381:TPHA_0N00610
uniprot id: G8C114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1071381:TPHA 0L00210
gene id: 1071381:TPHA_0L00210
uniprot id: G8BZQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1071381:TPHA 0N01750
gene id: 1071381:TPHA_0N01750
uniprot id: G8C1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0K01860
gene id: 1071381:TPHA_0K01860
uniprot id: G8BZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

1071381:TPHA 0I00800
gene id: 1071381:TPHA_0I00800
uniprot id: G8BXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

1071381:TPHA 0C04930
gene id: 1071381:TPHA_0C04930
uniprot id: G8BQX9
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0H00300
gene id: 1071381:TPHA_0H00300
uniprot id: G8BWT6
names: Similarity
messages: Belongs to the GCN1 family.

1071381:TPHA 0G00970
gene id: 1071381:TPHA_0G00970
uniprot id: G8BVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0D02640
gene id: 1071381:TPHA_0D02640
uniprot id: G8BST0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

1071381:TPHA 0H02200
gene id: 1071381:TPHA_0H02200
uniprot id: G8BWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B02500
gene id: 1071381:TPHA_0B02500
uniprot id: G8BPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

1071381:TPHA 0J00410
gene id: 1071381:TPHA_0J00410
uniprot id: G8BYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0H01860
gene id: 1071381:TPHA_0H01860
uniprot id: G8BX87
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

1071381:TPHA 0A01560
gene id: 1071381:TPHA_0A01560
uniprot id: G8BMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

1071381:TPHA 0A03820
gene id: 1071381:TPHA_0A03820
uniprot id: G8BNI0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

1071381:TPHA 0C01110
gene id: 1071381:TPHA_0C01110
uniprot id: G8BR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0A04320
gene id: 1071381:TPHA_0A04320
uniprot id: G8BNM8
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0G00710
gene id: 1071381:TPHA_0G00710
uniprot id: G8BVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1071381:TPHA 0F02410
gene id: 1071381:TPHA_0F02410
uniprot id: G8BUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

1071381:TPHA 0M01750
gene id: 1071381:TPHA_0M01750
uniprot id: G8C0N5
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071381:TPHA 0A03040
gene id: 1071381:TPHA_0A03040
uniprot id: G8BNA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

1071381:TPHA 0C00230
gene id: 1071381:TPHA_0C00230
uniprot id: G8BR04
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071381:TPHA 0A05700
gene id: 1071381:TPHA_0A05700
uniprot id: G8BP16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0E03050
gene id: 1071381:TPHA_0E03050
uniprot id: G8BU17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

1071381:TPHA 0G03450
gene id: 1071381:TPHA_0G03450
uniprot id: G8BWA7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C04100
gene id: 1071381:TPHA_0C04100
uniprot id: G8BQP8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1071381:TPHA 0H00360
gene id: 1071381:TPHA_0H00360
uniprot id: G8BWU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

1071381:TPHA 0K01810
gene id: 1071381:TPHA_0K01810
uniprot id: G8BZI5
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0K00740
gene id: 1071381:TPHA_0K00740
uniprot id: G8BZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1071381:TPHA 0C03950
gene id: 1071381:TPHA_0C03950
uniprot id: G8BQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

1071381:TPHA 0A01550
gene id: 1071381:TPHA_0A01550
uniprot id: G8BMW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0P01000
gene id: 1071381:TPHA_0P01000
uniprot id: G8C280
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

1071381:TPHA 0G02900
gene id: 1071381:TPHA_0G02900
uniprot id: G8BW53
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1071381:TPHA 0C03620
gene id: 1071381:TPHA_0C03620
uniprot id: G8BQK2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0K00480
gene id: 1071381:TPHA_0K00480
uniprot id: G8BZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

1071381:TPHA 0F00220
gene id: 1071381:TPHA_0F00220
uniprot id: G8BUS7
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

1071381:TPHA 0G03580
gene id: 1071381:TPHA_0G03580
uniprot id: G8BWC0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071381:TPHA 0B01270
gene id: 1071381:TPHA_0B01270
uniprot id: G8BP69
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0L01570
gene id: 1071381:TPHA_0L01570
uniprot id: G8C032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1071381:TPHA 0M00290
gene id: 1071381:TPHA_0M00290
uniprot id: G8C0U5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B00800
gene id: 1071381:TPHA_0B00800
uniprot id: G8BQF5
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0H01680
gene id: 1071381:TPHA_0H01680
uniprot id: G8BX70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC110 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.
messages: Nucleus
messages: spindle pole body

1071381:TPHA 0D00730
gene id: 1071381:TPHA_0D00730
uniprot id: G8BS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

1071381:TPHA 0J01830
gene id: 1071381:TPHA_0J01830
uniprot id: G8BYR2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1071381:TPHA 0B04370
gene id: 1071381:TPHA_0B04370
uniprot id: G8BQ25
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0H01840
gene id: 1071381:TPHA_0H01840
uniprot id: G8BX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

1071381:TPHA 0A02190
gene id: 1071381:TPHA_0A02190
uniprot id: G8BN23
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1071381:TPHA 0A04660
gene id: 1071381:TPHA_0A04660
uniprot id: G8BNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071381:TPHA 0F00980
gene id: 1071381:TPHA_0F00980
uniprot id: G8BV02
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0C02480
gene id: 1071381:TPHA_0C02480
uniprot id: G8BRM5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

1071381:TPHA 0G01070
gene id: 1071381:TPHA_0G01070
uniprot id: G8BVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

1071381:TPHA 0J00800
gene id: 1071381:TPHA_0J00800
uniprot id: G8BYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1071381:TPHA 0P00200
gene id: 1071381:TPHA_0P00200
uniprot id: G8C200
names: Similarity
messages: Belongs to the FYV7 family.

1071381:TPHA 0B03940
gene id: 1071381:TPHA_0B03940
uniprot id: G8BPY5
names: Similarity
messages: Belongs to the TPP enzyme family.

1071381:TPHA 0A02740
gene id: 1071381:TPHA_0A02740
uniprot id: G8BN78
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1071381:TPHA 0L00460
gene id: 1071381:TPHA_0L00460
uniprot id: G8BZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

1071381:TPHA 0M01820
gene id: 1071381:TPHA_0M01820
uniprot id: G8C0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A04230
gene id: 1071381:TPHA_0A04230
uniprot id: G8BNM0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1071381:TPHA 0J00340
gene id: 1071381:TPHA_0J00340
uniprot id: G8BYB5
names: Similarity
messages: Belongs to the SGT family.

1071381:TPHA 0F03290
gene id: 1071381:TPHA_0F03290
uniprot id: G8BUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

1071381:TPHA 0A05330
gene id: 1071381:TPHA_0A05330
uniprot id: G8BNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
messages: Homodimer.
messages: Preautophagosomal structure

1071381:TPHA 0H01230
gene id: 1071381:TPHA_0H01230
uniprot id: G8BX27
names: Similarity
messages: Belongs to the FMO family.

1071381:TPHA 0K01530
gene id: 1071381:TPHA_0K01530
uniprot id: G8BZF8
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

1071381:TPHA 0J01760
gene id: 1071381:TPHA_0J01760
uniprot id: G8BYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1071381:TPHA 0C04970
gene id: 1071381:TPHA_0C04970
uniprot id: G8BQY3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D04130
gene id: 1071381:TPHA_0D04130
uniprot id: G8BT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0B01570
gene id: 1071381:TPHA_0B01570
uniprot id: G8BP98
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0A00970
gene id: 1071381:TPHA_0A00970
uniprot id: G8BMQ4
names: Similarity
messages: Belongs to the PP2C family.

1071381:TPHA 0N01890
gene id: 1071381:TPHA_0N01890
uniprot id: G8C1E2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

1071381:TPHA 0J01950
gene id: 1071381:TPHA_0J01950
uniprot id: G8BYS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0A04690
gene id: 1071381:TPHA_0A04690
uniprot id: G8BNR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1071381:TPHA 0H00520
gene id: 1071381:TPHA_0H00520
uniprot id: G8BWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0O00450
gene id: 1071381:TPHA_0O00450
uniprot id: G8C1I8
names: Similarity
messages: Belongs to the NAD kinase family.

1071381:TPHA 0K00600
gene id: 1071381:TPHA_0K00600
uniprot id: G8BZ66
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0L01160
gene id: 1071381:TPHA_0L01160
uniprot id: G8BZZ5
names: Similarity
messages: Belongs to the HMBS family.

1071381:TPHA 0D00680
gene id: 1071381:TPHA_0D00680
uniprot id: G8BS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071381:TPHA 0A00810
gene id: 1071381:TPHA_0A00810
uniprot id: G8BMN8
names: Similarity
messages: Belongs to the SIN1 family.

1071381:TPHA 0I01340
gene id: 1071381:TPHA_0I01340
uniprot id: G8BXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

1071381:TPHA 0I02020
gene id: 1071381:TPHA_0I02020
uniprot id: G8BXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

1071381:TPHA 0A05480
gene id: 1071381:TPHA_0A05480
uniprot id: G8BNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071381:TPHA 0K00880
gene id: 1071381:TPHA_0K00880
uniprot id: G8BZ94
names: Function
names: Similarity
messages: Belongs to the RGI1 family.
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

1071381:TPHA 0M00900
gene id: 1071381:TPHA_0M00900
uniprot id: G8C0F0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0G00360
gene id: 1071381:TPHA_0G00360
uniprot id: G8BVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

1071381:TPHA 0A05350
gene id: 1071381:TPHA_0A05350
uniprot id: G8BNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1071381:TPHA 0C00320
gene id: 1071381:TPHA_0C00320
uniprot id: G8BR13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

1071381:TPHA 0C04580
gene id: 1071381:TPHA_0C04580
uniprot id: G8BQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1071381:TPHA 0N00960
gene id: 1071381:TPHA_0N00960
uniprot id: G8C149
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

1071381:TPHA 0G03300
gene id: 1071381:TPHA_0G03300
uniprot id: G8BW92
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

1071381:TPHA 0J00250
gene id: 1071381:TPHA_0J00250
uniprot id: G8BYA7
names: Similarity
messages: Belongs to the MYBBP1A family.

1071381:TPHA 0C04140
gene id: 1071381:TPHA_0C04140
uniprot id: G8BQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

1071381:TPHA 0C03570
gene id: 1071381:TPHA_0C03570
uniprot id: G8BQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

1071381:TPHA 0A02790
gene id: 1071381:TPHA_0A02790
uniprot id: G8BN82
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G01320
gene id: 1071381:TPHA_0G01320
uniprot id: G8BVP1
names: Similarity
messages: Belongs to the phosducin family.

1071381:TPHA 0L00650
gene id: 1071381:TPHA_0L00650
uniprot id: G8BZU3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A03490
gene id: 1071381:TPHA_0A03490
uniprot id: G8BNE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1071381:TPHA 0C02950
gene id: 1071381:TPHA_0C02950
uniprot id: G8BRS2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071381:TPHA 0O00490
gene id: 1071381:TPHA_0O00490
uniprot id: G8C1J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

1071381:TPHA 0I01730
gene id: 1071381:TPHA_0I01730
uniprot id: G8BXP9
names: Similarity
messages: Belongs to the MGR2 family.

1071381:TPHA 0N01140
gene id: 1071381:TPHA_0N01140
uniprot id: G8C167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

1071381:TPHA 0K00910
gene id: 1071381:TPHA_0K00910
uniprot id: G8BZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

1071381:TPHA 0G00150
gene id: 1071381:TPHA_0G00150
uniprot id: G8BVC7
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0L00720
gene id: 1071381:TPHA_0L00720
uniprot id: G8BZV0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B00670
gene id: 1071381:TPHA_0B00670
uniprot id: G8BQE2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1071381:TPHA 0F02060
gene id: 1071381:TPHA_0F02060
uniprot id: G8BVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0C00620
gene id: 1071381:TPHA_0C00620
uniprot id: G8BR43
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1071381:TPHA 0N01350
gene id: 1071381:TPHA_0N01350
uniprot id: G8C188
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1071381:TPHA 0F02590
gene id: 1071381:TPHA_0F02590
uniprot id: G8BUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0A04380
gene id: 1071381:TPHA_0A04380
uniprot id: G8BNN3
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0E03620
gene id: 1071381:TPHA_0E03620
uniprot id: G8BUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

1071381:TPHA 0N00730
gene id: 1071381:TPHA_0N00730
uniprot id: G8C126
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071381:TPHA 0F03010
gene id: 1071381:TPHA_0F03010
uniprot id: G8BUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071381:TPHA 0A02380
gene id: 1071381:TPHA_0A02380
uniprot id: G8BN42
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0B00430
gene id: 1071381:TPHA_0B00430
uniprot id: G8BQB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

1071381:TPHA 0I02390
gene id: 1071381:TPHA_0I02390
uniprot id: G8BXW4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071381:TPHA 0J03040
gene id: 1071381:TPHA_0J03040
uniprot id: G8BY73
names: Similarity
messages: Belongs to the peptidase M28 family.

1071381:TPHA 0B03680
gene id: 1071381:TPHA_0B03680
uniprot id: G8BPV9
names: Similarity
messages: Belongs to the UPF0357 family.

1071381:TPHA 0P01190
gene id: 1071381:TPHA_0P01190
uniprot id: G8C299
names: Similarity
messages: Belongs to the CNOT9 family.

1071381:TPHA 0G02520
gene id: 1071381:TPHA_0G02520
uniprot id: G8BW09
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0G01800
gene id: 1071381:TPHA_0G01800
uniprot id: G8BVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

1071381:TPHA 0M01550
gene id: 1071381:TPHA_0M01550
uniprot id: G8C0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0B01600
gene id: 1071381:TPHA_0B01600
uniprot id: G8BPA2
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

1071381:TPHA 0B03770
gene id: 1071381:TPHA_0B03770
uniprot id: G8BPW8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N00880
gene id: 1071381:TPHA_0N00880
uniprot id: G8C141
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1071381:TPHA 0D03900
gene id: 1071381:TPHA_0D03900
uniprot id: G8BT52
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D00210
gene id: 1071381:TPHA_0D00210
uniprot id: G8BS44
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

1071381:TPHA 0B02370
gene id: 1071381:TPHA_0B02370
uniprot id: G8BPH9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1071381:TPHA 0H02150
gene id: 1071381:TPHA_0H02150
uniprot id: G8BWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

1071381:TPHA 0E00380
gene id: 1071381:TPHA_0E00380
uniprot id: G8BTA6
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

1071381:TPHA 0E03690
gene id: 1071381:TPHA_0E03690
uniprot id: G8BU80
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

1071381:TPHA 0C04810
gene id: 1071381:TPHA_0C04810
uniprot id: G8BQW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

1071381:TPHA 0L00810
gene id: 1071381:TPHA_0L00810
uniprot id: G8BZW0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P01120
gene id: 1071381:TPHA_0P01120
uniprot id: G8C292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1071381:TPHA 0J02490
gene id: 1071381:TPHA_0J02490
uniprot id: G8BYX7
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J01540
gene id: 1071381:TPHA_0J01540
uniprot id: G8BYN3
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

1071381:TPHA 0B02790
gene id: 1071381:TPHA_0B02790
uniprot id: G8BPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

1071381:TPHA 0H01130
gene id: 1071381:TPHA_0H01130
uniprot id: G8BX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1071381:TPHA 0B04610
gene id: 1071381:TPHA_0B04610
uniprot id: G8BQ49
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

1071381:TPHA 0M01500
gene id: 1071381:TPHA_0M01500
uniprot id: G8C0L0
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0H00930
gene id: 1071381:TPHA_0H00930
uniprot id: G8BWZ7
names: Similarity
messages: Belongs to the TOG/XMAP215 family.

1071381:TPHA 0A02160
gene id: 1071381:TPHA_0A02160
uniprot id: G8BN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1071381:TPHA 0C01530
gene id: 1071381:TPHA_0C01530
uniprot id: G8BRD3
names: Similarity
messages: Belongs to the MAPRE family.

1071381:TPHA 0I00370
gene id: 1071381:TPHA_0I00370
uniprot id: G8BXB6
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

1071381:TPHA 0B04590
gene id: 1071381:TPHA_0B04590
uniprot id: G8BQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0A02150
gene id: 1071381:TPHA_0A02150
uniprot id: G8BN19
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L01070
gene id: 1071381:TPHA_0L01070
uniprot id: G8BZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

1071381:TPHA 0E02320
gene id: 1071381:TPHA_0E02320
uniprot id: G8BTU6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1071381:TPHA 0L01890
gene id: 1071381:TPHA_0L01890
uniprot id: G8C064
names: Similarity
messages: Belongs to the multicopper oxidase family.

1071381:TPHA 0O00180
gene id: 1071381:TPHA_0O00180
uniprot id: G8C1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

1071381:TPHA 0A01840
gene id: 1071381:TPHA_0A01840
uniprot id: G8BMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1071381:TPHA 0C04630
gene id: 1071381:TPHA_0C04630
uniprot id: G8BQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

1071381:TPHA 0I00690
gene id: 1071381:TPHA_0I00690
uniprot id: G8BXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

1071381:TPHA 0I02520
gene id: 1071381:TPHA_0I02520
uniprot id: G8BXX6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0K01400
gene id: 1071381:TPHA_0K01400
uniprot id: G8BZE5
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

1071381:TPHA 0C02350
gene id: 1071381:TPHA_0C02350
uniprot id: G8BRL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1071381:TPHA 0L01210
gene id: 1071381:TPHA_0L01210
uniprot id: G8C000
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0F01320
gene id: 1071381:TPHA_0F01320
uniprot id: G8BV35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0H02970
gene id: 1071381:TPHA_0H02970
uniprot id: G8BWP9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071381:TPHA 0B00200
gene id: 1071381:TPHA_0B00200
uniprot id: G8BQ95
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0M00280
gene id: 1071381:TPHA_0M00280
uniprot id: G8C0U4
names: Similarity
messages: Belongs to the pirin family.

1071381:TPHA 0C02080
gene id: 1071381:TPHA_0C02080
uniprot id: G8BRI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071381:TPHA 0E02300
gene id: 1071381:TPHA_0E02300
uniprot id: G8BTU4
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

1071381:TPHA 0B02060
gene id: 1071381:TPHA_0B02060
uniprot id: G8BPE7
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071381:TPHA 0F00200
gene id: 1071381:TPHA_0F00200
uniprot id: G8BUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

1071381:TPHA 0L01900
gene id: 1071381:TPHA_0L01900
uniprot id: G8C065
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

1071381:TPHA 0B03570
gene id: 1071381:TPHA_0B03570
uniprot id: G8BPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Golgi apparatus

1071381:TPHA 0N01180
gene id: 1071381:TPHA_0N01180
uniprot id: G8C171
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1071381:TPHA 0A01660
gene id: 1071381:TPHA_0A01660
uniprot id: G8BMX1
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1071381:TPHA 0N01260
gene id: 1071381:TPHA_0N01260
uniprot id: G8C179
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

1071381:TPHA 0A05770
gene id: 1071381:TPHA_0A05770
uniprot id: G8BP23
names: Similarity
messages: Belongs to the peptidase S10 family.

1071381:TPHA 0J02370
gene id: 1071381:TPHA_0J02370
uniprot id: G8BYW5
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0H00150
gene id: 1071381:TPHA_0H00150
uniprot id: G8BWS2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1071381:TPHA 0E03500
gene id: 1071381:TPHA_0E03500
uniprot id: G8BU62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SOP4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
messages: Membrane

1071381:TPHA 0L01240
gene id: 1071381:TPHA_0L01240
uniprot id: G8C003
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0B00350
gene id: 1071381:TPHA_0B00350
uniprot id: G8BQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

1071381:TPHA 0B02820
gene id: 1071381:TPHA_0B02820
uniprot id: G8BPM3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1071381:TPHA 0J01080
gene id: 1071381:TPHA_0J01080
uniprot id: G8BYI8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0O00270
gene id: 1071381:TPHA_0O00270
uniprot id: G8C1H1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1071381:TPHA 0G02830
gene id: 1071381:TPHA_0G02830
uniprot id: G8BW43
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1071381:TPHA 0B04090
gene id: 1071381:TPHA_0B04090
uniprot id: G8BPZ9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1071381:TPHA 0K01560
gene id: 1071381:TPHA_0K01560
uniprot id: G8BZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

1071381:TPHA 0J01380
gene id: 1071381:TPHA_0J01380
uniprot id: G8BYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0K00860
gene id: 1071381:TPHA_0K00860
uniprot id: G8BZ92
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

1071381:TPHA 0J01820
gene id: 1071381:TPHA_0J01820
uniprot id: G8BYR1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D02020
gene id: 1071381:TPHA_0D02020
uniprot id: G8BSL9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1071381:TPHA 0J01460
gene id: 1071381:TPHA_0J01460
uniprot id: G8BYM6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A00900
gene id: 1071381:TPHA_0A00900
uniprot id: G8BMP7
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

1071381:TPHA 0C01100
gene id: 1071381:TPHA_0C01100
uniprot id: G8BR90
names: Similarity
messages: Belongs to the RutC family.

1071381:TPHA 0F02090
gene id: 1071381:TPHA_0F02090
uniprot id: G8BVA9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0E00350
gene id: 1071381:TPHA_0E00350
uniprot id: G8BTA3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D03280
gene id: 1071381:TPHA_0D03280
uniprot id: G8BSZ3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B02350
gene id: 1071381:TPHA_0B02350
uniprot id: G8BPH7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H00160
gene id: 1071381:TPHA_0H00160
uniprot id: G8BWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

1071381:TPHA 0E01980
gene id: 1071381:TPHA_0E01980
uniprot id: G8BTR2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D02610
gene id: 1071381:TPHA_0D02610
uniprot id: G8BSS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1071381:TPHA 0P00570
gene id: 1071381:TPHA_0P00570
uniprot id: G8C237
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071381:TPHA 0P00110
gene id: 1071381:TPHA_0P00110
uniprot id: G8C1Z1
names: Subcellular Location Annotation
messages: Cell surface

1071381:TPHA 0A00640
gene id: 1071381:TPHA_0A00640
uniprot id: G8BMM1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A05620
gene id: 1071381:TPHA_0A05620
uniprot id: G8BP08
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00320
gene id: 1071381:TPHA_0L00320
uniprot id: G8BZR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071381:TPHA 0N01960
gene id: 1071381:TPHA_0N01960
uniprot id: G8C1E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1071381:TPHA 0A00650
gene id: 1071381:TPHA_0A00650
uniprot id: G8BMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus

1071381:TPHA 0C04540
gene id: 1071381:TPHA_0C04540
uniprot id: G8BQU3
names: Similarity
messages: Belongs to the peptidase C48 family.

1071381:TPHA 0C00430
gene id: 1071381:TPHA_0C00430
uniprot id: G8BR24
names: Similarity
messages: Belongs to the GroES chaperonin family.

1071381:TPHA 0C00630
gene id: 1071381:TPHA_0C00630
uniprot id: G8BR44
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071381:TPHA 0M01140
gene id: 1071381:TPHA_0M01140
uniprot id: G8C0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

1071381:TPHA 0G03210
gene id: 1071381:TPHA_0G03210
uniprot id: G8BW83
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0B00840
gene id: 1071381:TPHA_0B00840
uniprot id: G8BQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

1071381:TPHA 0A04140
gene id: 1071381:TPHA_0A04140
uniprot id: G8BNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0E00170
gene id: 1071381:TPHA_0E00170
uniprot id: G8BT86
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1071381:TPHA 0B04750
gene id: 1071381:TPHA_0B04750
uniprot id: G8BQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0A03140
gene id: 1071381:TPHA_0A03140
uniprot id: G8BNB3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1071381:TPHA 0I00980
gene id: 1071381:TPHA_0I00980
uniprot id: G8BXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

1071381:TPHA 0A03750
gene id: 1071381:TPHA_0A03750
uniprot id: G8BNH3
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

1071381:TPHA 0A05730
gene id: 1071381:TPHA_0A05730
uniprot id: G8BP19
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0K00380
gene id: 1071381:TPHA_0K00380
uniprot id: G8BZ44
names: Similarity
messages: Belongs to the UTP6 family.

1071381:TPHA 0I02620
gene id: 1071381:TPHA_0I02620
uniprot id: G8BXY5
names: Similarity
messages: Belongs to the VPS26 family.

1071381:TPHA 0D00740
gene id: 1071381:TPHA_0D00740
uniprot id: G8BS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

1071381:TPHA 0J02710
gene id: 1071381:TPHA_0J02710
uniprot id: G8BYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0F03650
gene id: 1071381:TPHA_0F03650
uniprot id: G8BUQ9
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0A05250
gene id: 1071381:TPHA_0A05250
uniprot id: G8BNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1071381:TPHA 0C01200
gene id: 1071381:TPHA_0C01200
uniprot id: G8BRA0
names: Similarity
messages: Belongs to the aspartokinase family.

1071381:TPHA 0G00580
gene id: 1071381:TPHA_0G00580
uniprot id: G8BVG6
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

1071381:TPHA 0E02770
gene id: 1071381:TPHA_0E02770
uniprot id: G8BTY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

1071381:TPHA 0E01410
gene id: 1071381:TPHA_0E01410
uniprot id: G8BTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0E01690
gene id: 1071381:TPHA_0E01690
uniprot id: G8BTN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

1071381:TPHA 0B00720
gene id: 1071381:TPHA_0B00720
uniprot id: G8BQE7
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

1071381:TPHA 0C01520
gene id: 1071381:TPHA_0C01520
uniprot id: G8BRD2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071381:TPHA 0I00290
gene id: 1071381:TPHA_0I00290
uniprot id: G8BXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

1071381:TPHA 0K01020
gene id: 1071381:TPHA_0K01020
uniprot id: G8BZA8
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

1071381:TPHA 0K01440
gene id: 1071381:TPHA_0K01440
uniprot id: G8BZE9
names: Similarity
messages: Belongs to the PRP18 family.

1071381:TPHA 0K02080
gene id: 1071381:TPHA_0K02080
uniprot id: G8BZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

1071381:TPHA 0C02690
gene id: 1071381:TPHA_0C02690
uniprot id: G8BRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

1071381:TPHA 0M01470
gene id: 1071381:TPHA_0M01470
uniprot id: G8C0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

1071381:TPHA 0A04700
gene id: 1071381:TPHA_0A04700
uniprot id: G8BNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0D00610
gene id: 1071381:TPHA_0D00610
uniprot id: G8BS84
names: Similarity
messages: Belongs to the peptidase C48 family.

1071381:TPHA 0B00560
gene id: 1071381:TPHA_0B00560
uniprot id: G8BQD1
names: Similarity
messages: Belongs to the TSR2 family.

1071381:TPHA 0F02140
gene id: 1071381:TPHA_0F02140
uniprot id: G8BVB4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G01020
gene id: 1071381:TPHA_0G01020
uniprot id: G8BVL0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0L02310
gene id: 1071381:TPHA_0L02310
uniprot id: G8C0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B00210
gene id: 1071381:TPHA_0B00210
uniprot id: G8BQ96
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0C02500
gene id: 1071381:TPHA_0C02500
uniprot id: G8BRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

1071381:TPHA 0F03140
gene id: 1071381:TPHA_0F03140
uniprot id: G8BUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

1071381:TPHA 0I03040
gene id: 1071381:TPHA_0I03040
uniprot id: G8BY27
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1071381:TPHA 0L02350
gene id: 1071381:TPHA_0L02350
uniprot id: G8C0A8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0N00940
gene id: 1071381:TPHA_0N00940
uniprot id: G8C147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

1071381:TPHA 0A02720
gene id: 1071381:TPHA_0A02720
uniprot id: G8BN76
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

1071381:TPHA 0I02630
gene id: 1071381:TPHA_0I02630
uniprot id: G8BXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B04550
gene id: 1071381:TPHA_0B04550
uniprot id: G8BQ43
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1071381:TPHA 0K00400
gene id: 1071381:TPHA_0K00400
uniprot id: G8BZ46
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1071381:TPHA 0I02220
gene id: 1071381:TPHA_0I02220
uniprot id: G8BXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

1071381:TPHA 0J00200
gene id: 1071381:TPHA_0J00200
uniprot id: G8BYA2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

1071381:TPHA 0A01070
gene id: 1071381:TPHA_0A01070
uniprot id: G8BMR4
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

1071381:TPHA 0D02230
gene id: 1071381:TPHA_0D02230
uniprot id: G8BSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

1071381:TPHA 0C02390
gene id: 1071381:TPHA_0C02390
uniprot id: G8BRL6
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

1071381:TPHA 0G01460
gene id: 1071381:TPHA_0G01460
uniprot id: G8BVQ5
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1071381:TPHA 0B03240
gene id: 1071381:TPHA_0B03240
uniprot id: G8BPR5
names: Similarity
messages: Belongs to the FGGY kinase family.

1071381:TPHA 0L00300
gene id: 1071381:TPHA_0L00300
uniprot id: G8BZQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

1071381:TPHA 0L02280
gene id: 1071381:TPHA_0L02280
uniprot id: G8C0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

1071381:TPHA 0G02980
gene id: 1071381:TPHA_0G02980
uniprot id: G8BW61
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

1071381:TPHA 0J01370
gene id: 1071381:TPHA_0J01370
uniprot id: G8BYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

1071381:TPHA 0H01870
gene id: 1071381:TPHA_0H01870
uniprot id: G8BX88
names: Similarity
messages: Belongs to the syntaxin family.

1071381:TPHA 0G02870
gene id: 1071381:TPHA_0G02870
uniprot id: G8BW47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0E02030
gene id: 1071381:TPHA_0E02030
uniprot id: G8BTR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0N01950
gene id: 1071381:TPHA_0N01950
uniprot id: G8C1E8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N01790
gene id: 1071381:TPHA_0N01790
uniprot id: G8C1D2
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1071381:TPHA 0O00880
gene id: 1071381:TPHA_0O00880
uniprot id: G8C1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

1071381:TPHA 0E03250
gene id: 1071381:TPHA_0E03250
uniprot id: G8BU37
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071381:TPHA 0E00980
gene id: 1071381:TPHA_0E00980
uniprot id: G8BTG4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1071381:TPHA 0M00510
gene id: 1071381:TPHA_0M00510
uniprot id: G8C0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

1071381:TPHA 0P01180
gene id: 1071381:TPHA_0P01180
uniprot id: G8C298
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071381:TPHA 0L00200
gene id: 1071381:TPHA_0L00200
uniprot id: G8BZP9
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1071381:TPHA 0B03900
gene id: 1071381:TPHA_0B03900
uniprot id: G8BPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0C00180
gene id: 1071381:TPHA_0C00180
uniprot id: G8BQZ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1071381:TPHA 0D04280
gene id: 1071381:TPHA_0D04280
uniprot id: G8BRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

1071381:TPHA 0A00490
gene id: 1071381:TPHA_0A00490
uniprot id: G8BMK6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1071381:TPHA 0N00820
gene id: 1071381:TPHA_0N00820
uniprot id: G8C135
names: Subcellular Location Annotation
messages: Membrane
messages: cell wall

1071381:TPHA 0O00480
gene id: 1071381:TPHA_0O00480
uniprot id: G8C1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

1071381:TPHA 0K01220
gene id: 1071381:TPHA_0K01220
uniprot id: G8BZC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

1071381:TPHA 0I02420
gene id: 1071381:TPHA_0I02420
uniprot id: G8BXW7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071381:TPHA 0F00210
gene id: 1071381:TPHA_0F00210
uniprot id: G8BUS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1071381:TPHA 0J00330
gene id: 1071381:TPHA_0J00330
uniprot id: G8BYB4
names: Similarity
messages: Belongs to the UPF0507 family.

1071381:TPHA 0D00380
gene id: 1071381:TPHA_0D00380
uniprot id: G8BS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

1071381:TPHA 0F03060
gene id: 1071381:TPHA_0F03060
uniprot id: G8BUK1
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1071381:TPHA 0M01070
gene id: 1071381:TPHA_0M01070
uniprot id: G8C0G7
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1071381:TPHA 0F01350
gene id: 1071381:TPHA_0F01350
uniprot id: G8BV38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

1071381:TPHA 0E00340
gene id: 1071381:TPHA_0E00340
uniprot id: G8BTA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

1071381:TPHA 0C03990
gene id: 1071381:TPHA_0C03990
uniprot id: G8BQN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1071381:TPHA 0I01840
gene id: 1071381:TPHA_0I01840
uniprot id: G8BXR0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071381:TPHA 0D03820
gene id: 1071381:TPHA_0D03820
uniprot id: G8BT44
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

1071381:TPHA 0J01130
gene id: 1071381:TPHA_0J01130
uniprot id: G8BYJ3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071381:TPHA 0D02920
gene id: 1071381:TPHA_0D02920
uniprot id: G8BSV7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1071381:TPHA 0I01310
gene id: 1071381:TPHA_0I01310
uniprot id: G8BXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

1071381:TPHA 0J02260
gene id: 1071381:TPHA_0J02260
uniprot id: G8BYV4
names: Similarity
messages: Belongs to the MAD1 family.

1071381:TPHA 0D04470
gene id: 1071381:TPHA_0D04470
uniprot id: G8BS06
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O00940
gene id: 1071381:TPHA_0O00940
uniprot id: G8C1N5
names: Similarity
messages: Belongs to the SWM2 family.

1071381:TPHA 0M01830
gene id: 1071381:TPHA_0M01830
uniprot id: G8C0P3
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0E02240
gene id: 1071381:TPHA_0E02240
uniprot id: G8BTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

1071381:TPHA 0P00840
gene id: 1071381:TPHA_0P00840
uniprot id: G8C264
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

1071381:TPHA 0B01870
gene id: 1071381:TPHA_0B01870
uniprot id: G8BPC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

1071381:TPHA 0J01040
gene id: 1071381:TPHA_0J01040
uniprot id: G8BYI4
names: Similarity
messages: Belongs to the AIM9 family.

1071381:TPHA 0E00270
gene id: 1071381:TPHA_0E00270
uniprot id: G8BT95
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1071381:TPHA 0A06090
gene id: 1071381:TPHA_0A06090
uniprot id: G8BP54
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0I03260
gene id: 1071381:TPHA_0I03260
uniprot id: G8BY49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0H01950
gene id: 1071381:TPHA_0H01950
uniprot id: G8BWE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1071381:TPHA 0G03090
gene id: 1071381:TPHA_0G03090
uniprot id: G8BW72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

1071381:TPHA 0A00700
gene id: 1071381:TPHA_0A00700
uniprot id: G8BMM7
names: Similarity
messages: Belongs to the VPS52 family.

1071381:TPHA 0K01210
gene id: 1071381:TPHA_0K01210
uniprot id: G8BZC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

1071381:TPHA 0O00160
gene id: 1071381:TPHA_0O00160
uniprot id: G8C1G0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N00560
gene id: 1071381:TPHA_0N00560
uniprot id: G8C109
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071381:TPHA 0P00770
gene id: 1071381:TPHA_0P00770
uniprot id: G8C257
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071381:TPHA 0E04070
gene id: 1071381:TPHA_0E04070
uniprot id: G8BUB6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0B00570
gene id: 1071381:TPHA_0B00570
uniprot id: G8BQD2
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

1071381:TPHA 0P00780
gene id: 1071381:TPHA_0P00780
uniprot id: G8C258
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0G02390
gene id: 1071381:TPHA_0G02390
uniprot id: G8BVZ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1071381:TPHA 0G02600
gene id: 1071381:TPHA_0G02600
uniprot id: G8BW19
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071381:TPHA 0A00740
gene id: 1071381:TPHA_0A00740
uniprot id: G8BMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

1071381:TPHA 0B04860
gene id: 1071381:TPHA_0B04860
uniprot id: G8BQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

1071381:TPHA 0E02510
gene id: 1071381:TPHA_0E02510
uniprot id: G8BTW5
names: Similarity
messages: Belongs to the SAPS family.

1071381:TPHA 0J03010
gene id: 1071381:TPHA_0J03010
uniprot id: G8BY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

1071381:TPHA 0K00730
gene id: 1071381:TPHA_0K00730
uniprot id: G8BZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

1071381:TPHA 0O00200
gene id: 1071381:TPHA_0O00200
uniprot id: G8C1G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

1071381:TPHA 0P01710
gene id: 1071381:TPHA_0P01710
uniprot id: G8C2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

1071381:TPHA 0L01050
gene id: 1071381:TPHA_0L01050
uniprot id: G8BZY4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1071381:TPHA 0K02070
gene id: 1071381:TPHA_0K02070
uniprot id: G8BZL2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D03130
gene id: 1071381:TPHA_0D03130
uniprot id: G8BSX8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1071381:TPHA 0G02100
gene id: 1071381:TPHA_0G02100
uniprot id: G8BVW8
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071381:TPHA 0J03150
gene id: 1071381:TPHA_0J03150
uniprot id: G8BY83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1071381:TPHA 0B02210
gene id: 1071381:TPHA_0B02210
uniprot id: G8BPG2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1071381:TPHA 0O01410
gene id: 1071381:TPHA_0O01410
uniprot id: G8C1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).

1071381:TPHA 0A03130
gene id: 1071381:TPHA_0A03130
uniprot id: G8BNB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1071381:TPHA 0A03860
gene id: 1071381:TPHA_0A03860
uniprot id: G8BNI4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0N00920
gene id: 1071381:TPHA_0N00920
uniprot id: G8C145
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

1071381:TPHA 0K01090
gene id: 1071381:TPHA_0K01090
uniprot id: G8BZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

1071381:TPHA 0A04220
gene id: 1071381:TPHA_0A04220
uniprot id: G8BNL9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01430
gene id: 1071381:TPHA_0C01430
uniprot id: G8BRC3
names: Similarity
messages: Belongs to the peptidase C48 family.

1071381:TPHA 0E00710
gene id: 1071381:TPHA_0E00710
uniprot id: G8BTD8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

1071381:TPHA 0E02920
gene id: 1071381:TPHA_0E02920
uniprot id: G8BU04
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A03560
gene id: 1071381:TPHA_0A03560
uniprot id: G8BNF4
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

1071381:TPHA 0E02530
gene id: 1071381:TPHA_0E02530
uniprot id: G8BTW7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1071381:TPHA 0J02900
gene id: 1071381:TPHA_0J02900
uniprot id: G8BY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0D03670
gene id: 1071381:TPHA_0D03670
uniprot id: G8BT31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0O00390
gene id: 1071381:TPHA_0O00390
uniprot id: G8C1I2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0H02680
gene id: 1071381:TPHA_0H02680
uniprot id: G8BWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B00260
gene id: 1071381:TPHA_0B00260
uniprot id: G8BQZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1071381:TPHA 0A02950
gene id: 1071381:TPHA_0A02950
uniprot id: G8BN97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0M00640
gene id: 1071381:TPHA_0M00640
uniprot id: G8C0C4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00440
gene id: 1071381:TPHA_0L00440
uniprot id: G8BZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071381:TPHA 0A05430
gene id: 1071381:TPHA_0A05430
uniprot id: G8BNY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

1071381:TPHA 0C04670
gene id: 1071381:TPHA_0C04670
uniprot id: G8BQV5
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071381:TPHA 0H01960
gene id: 1071381:TPHA_0H01960
uniprot id: G8BWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071381:TPHA 0A00450
gene id: 1071381:TPHA_0A00450
uniprot id: G8BMK2
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1071381:TPHA 0G03290
gene id: 1071381:TPHA_0G03290
uniprot id: G8BW91
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1071381:TPHA 0F00810
gene id: 1071381:TPHA_0F00810
uniprot id: G8BUY5
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

1071381:TPHA 0O01280
gene id: 1071381:TPHA_0O01280
uniprot id: G8C1R8
names: Similarity
messages: Belongs to the SH3YL1 family.

1071381:TPHA 0L01030
gene id: 1071381:TPHA_0L01030
uniprot id: G8BZY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0D01620
gene id: 1071381:TPHA_0D01620
uniprot id: G8BSI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1071381:TPHA 0E01120
gene id: 1071381:TPHA_0E01120
uniprot id: G8BTH8
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1071381:TPHA 0F02270
gene id: 1071381:TPHA_0F02270
uniprot id: G8BUC2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1071381:TPHA 0C03670
gene id: 1071381:TPHA_0C03670
uniprot id: G8BQK7
names: Similarity
messages: Belongs to the lipin family.

1071381:TPHA 0B02020
gene id: 1071381:TPHA_0B02020
uniprot id: G8BPE3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1071381:TPHA 0I01770
gene id: 1071381:TPHA_0I01770
uniprot id: G8BXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1071381:TPHA 0H01120
gene id: 1071381:TPHA_0H01120
uniprot id: G8BX16
names: Similarity
messages: Belongs to the TFIIB family.

1071381:TPHA 0G00920
gene id: 1071381:TPHA_0G00920
uniprot id: G8BVK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

1071381:TPHA 0M01660
gene id: 1071381:TPHA_0M01660
uniprot id: G8C0M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1071381:TPHA 0F02600
gene id: 1071381:TPHA_0F02600
uniprot id: G8BUF4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D01350
gene id: 1071381:TPHA_0D01350
uniprot id: G8BSF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

1071381:TPHA 0K01710
gene id: 1071381:TPHA_0K01710
uniprot id: G8BZH6
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

1071381:TPHA 0B03040
gene id: 1071381:TPHA_0B03040
uniprot id: G8BPP5
names: Function
names: Similarity
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

1071381:TPHA 0G03180
gene id: 1071381:TPHA_0G03180
uniprot id: G8BW80
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

1071381:TPHA 0K00470
gene id: 1071381:TPHA_0K00470
uniprot id: G8BZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0K01080
gene id: 1071381:TPHA_0K01080
uniprot id: G8BZB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1071381:TPHA 0K00240
gene id: 1071381:TPHA_0K00240
uniprot id: G8BZ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

1071381:TPHA 0O01570
gene id: 1071381:TPHA_0O01570
uniprot id: G8C1U6
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1071381:TPHA 0C01650
gene id: 1071381:TPHA_0C01650
uniprot id: G8BRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC and thereby sterically blocks ODC homodimerization.
messages: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

1071381:TPHA 0H00550
gene id: 1071381:TPHA_0H00550
uniprot id: G8BWW1
names: Similarity
messages: Belongs to the YIP1 family.

1071381:TPHA 0O00440
gene id: 1071381:TPHA_0O00440
uniprot id: G8C1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

1071381:TPHA 0B02030
gene id: 1071381:TPHA_0B02030
uniprot id: G8BPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

1071381:TPHA 0B04040
gene id: 1071381:TPHA_0B04040
uniprot id: G8BPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

1071381:TPHA 0B04620
gene id: 1071381:TPHA_0B04620
uniprot id: G8BQ50
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0G03420
gene id: 1071381:TPHA_0G03420
uniprot id: G8BWA4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0K01970
gene id: 1071381:TPHA_0K01970
uniprot id: G8BZK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1071381:TPHA 0A02570
gene id: 1071381:TPHA_0A02570
uniprot id: G8BN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071381:TPHA 0G02595
gene id: 1071381:TPHA_0G02595
uniprot id: G8BW18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1071381:TPHA 0A04400
gene id: 1071381:TPHA_0A04400
uniprot id: G8BVI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0G03520
gene id: 1071381:TPHA_0G03520
uniprot id: G8BWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

1071381:TPHA 0N00570
gene id: 1071381:TPHA_0N00570
uniprot id: G8C110
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

1071381:TPHA 0D01570
gene id: 1071381:TPHA_0D01570
uniprot id: G8BSH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

1071381:TPHA 0D02180
gene id: 1071381:TPHA_0D02180
uniprot id: G8BSN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071381:TPHA 0F02040
gene id: 1071381:TPHA_0F02040
uniprot id: G8BVA4
names: Similarity
messages: Belongs to the peptidase M14 family.

1071381:TPHA 0B02160
gene id: 1071381:TPHA_0B02160
uniprot id: G8BPF7
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0B04540
gene id: 1071381:TPHA_0B04540
uniprot id: G8BQ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

1071381:TPHA 0I02580
gene id: 1071381:TPHA_0I02580
uniprot id: G8BXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071381:TPHA 0L01430
gene id: 1071381:TPHA_0L01430
uniprot id: G8C020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

1071381:TPHA 0B01170
gene id: 1071381:TPHA_0B01170
uniprot id: G8BP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

1071381:TPHA 0M01040
gene id: 1071381:TPHA_0M01040
uniprot id: G8C0G3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0P01390
gene id: 1071381:TPHA_0P01390
uniprot id: G8C2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1071381:TPHA 0D04000
gene id: 1071381:TPHA_0D04000
uniprot id: G8BT63
names: Function
names: Similarity
messages: Belongs to the RRG8 family.
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

1071381:TPHA 0E01510
gene id: 1071381:TPHA_0E01510
uniprot id: G8BTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

1071381:TPHA 0A01165
gene id: 1071381:TPHA_0A01165
uniprot id: G8BMS3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

1071381:TPHA 0F02470
gene id: 1071381:TPHA_0F02470
uniprot id: G8BUE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0C02050
gene id: 1071381:TPHA_0C02050
uniprot id: G8BRI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0B03320
gene id: 1071381:TPHA_0B03320
uniprot id: G8BPS3
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1071381:TPHA 0P01430
gene id: 1071381:TPHA_0P01430
uniprot id: G8C2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

1071381:TPHA 0I01830
gene id: 1071381:TPHA_0I01830
uniprot id: G8BXQ9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0M00130
gene id: 1071381:TPHA_0M00130
uniprot id: G8C0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0F00730
gene id: 1071381:TPHA_0F00730
uniprot id: G8BUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

1071381:TPHA 0I02360
gene id: 1071381:TPHA_0I02360
uniprot id: G8BXW1
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

1071381:TPHA 0F02750
gene id: 1071381:TPHA_0F02750
uniprot id: G8BUG9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1071381:TPHA 0F00510
gene id: 1071381:TPHA_0F00510
uniprot id: G8BUV6
names: Similarity
messages: Belongs to the isochorismatase family.

1071381:TPHA 0C03090
gene id: 1071381:TPHA_0C03090
uniprot id: G8BRT6
names: Similarity
messages: Belongs to the SUN family.

1071381:TPHA 0E03770
gene id: 1071381:TPHA_0E03770
uniprot id: G8BU88
names: Similarity
messages: Belongs to the hexokinase family.

1071381:TPHA 0K02090
gene id: 1071381:TPHA_0K02090
uniprot id: G8BZL4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0D03340
gene id: 1071381:TPHA_0D03340
uniprot id: G8BSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1071381:TPHA 0K01260
gene id: 1071381:TPHA_0K01260
uniprot id: G8BZD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0D00710
gene id: 1071381:TPHA_0D00710
uniprot id: G8BS93
names: Similarity
messages: Belongs to the peptidase M67A family.

1071381:TPHA 0B00530
gene id: 1071381:TPHA_0B00530
uniprot id: G8BQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

1071381:TPHA 0C04380
gene id: 1071381:TPHA_0C04380
uniprot id: G8BQS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1071381:TPHA 0F01130
gene id: 1071381:TPHA_0F01130
uniprot id: G8BV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

1071381:TPHA 0C02400
gene id: 1071381:TPHA_0C02400
uniprot id: G8BRL7
names: Similarity
messages: Belongs to the phosducin family.

1071381:TPHA 0L00920
gene id: 1071381:TPHA_0L00920
uniprot id: G8BZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

1071381:TPHA 0D01590
gene id: 1071381:TPHA_0D01590
uniprot id: G8BSH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0F03120
gene id: 1071381:TPHA_0F03120
uniprot id: G8BUK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

1071381:TPHA 0J02860
gene id: 1071381:TPHA_0J02860
uniprot id: G8BZ15
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0G00230
gene id: 1071381:TPHA_0G00230
uniprot id: G8BVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071381:TPHA 0C03150
gene id: 1071381:TPHA_0C03150
uniprot id: G8BRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

1071381:TPHA 0P01340
gene id: 1071381:TPHA_0P01340
uniprot id: G8C2B4
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

1071381:TPHA 0K01140
gene id: 1071381:TPHA_0K01140
uniprot id: G8BZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071381:TPHA 0B00630
gene id: 1071381:TPHA_0B00630
uniprot id: G8BQD8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

1071381:TPHA 0B03530
gene id: 1071381:TPHA_0B03530
uniprot id: G8BPU2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J01660
gene id: 1071381:TPHA_0J01660
uniprot id: G8BYP5
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

1071381:TPHA 0E03400
gene id: 1071381:TPHA_0E03400
uniprot id: G8BU52
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

1071381:TPHA 0A02130
gene id: 1071381:TPHA_0A02130
uniprot id: G8BN17
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1071381:TPHA 0L00850
gene id: 1071381:TPHA_0L00850
uniprot id: G8BZW4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0D02930
gene id: 1071381:TPHA_0D02930
uniprot id: G8BSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0M01940
gene id: 1071381:TPHA_0M01940
uniprot id: G8C0Q4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0D03480
gene id: 1071381:TPHA_0D03480
uniprot id: G8BT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1071381:TPHA 0B03740
gene id: 1071381:TPHA_0B03740
uniprot id: G8BPW5
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071381:TPHA 0D00190
gene id: 1071381:TPHA_0D00190
uniprot id: G8BS42
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1071381:TPHA 0J03210
gene id: 1071381:TPHA_0J03210
uniprot id: G8BY89
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1071381:TPHA 0B01470
gene id: 1071381:TPHA_0B01470
uniprot id: G8BP89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

1071381:TPHA 0J00910
gene id: 1071381:TPHA_0J00910
uniprot id: G8BYH1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

1071381:TPHA 0B02120
gene id: 1071381:TPHA_0B02120
uniprot id: G8BPF3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

1071381:TPHA 0E03110
gene id: 1071381:TPHA_0E03110
uniprot id: G8BU23
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1071381:TPHA 0B03300
gene id: 1071381:TPHA_0B03300
uniprot id: G8BPS1
names: Similarity
messages: Belongs to the peptidase M24 family.

1071381:TPHA 0K01310
gene id: 1071381:TPHA_0K01310
uniprot id: G8BZD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1071381:TPHA 0G02210
gene id: 1071381:TPHA_0G02210
uniprot id: G8BVX9
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

1071381:TPHA 0P01690
gene id: 1071381:TPHA_0P01690
uniprot id: G8C2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0M01510
gene id: 1071381:TPHA_0M01510
uniprot id: G8C0L1
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071381:TPHA 0A04390
gene id: 1071381:TPHA_0A04390
uniprot id: G8BNN4
names: Similarity
messages: Belongs to the PPase family.

1071381:TPHA 0N00590
gene id: 1071381:TPHA_0N00590
uniprot id: G8C112
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

1071381:TPHA 0G00800
gene id: 1071381:TPHA_0G00800
uniprot id: G8BVI8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0A05790
gene id: 1071381:TPHA_0A05790
uniprot id: G8BP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

1071381:TPHA 0G01060
gene id: 1071381:TPHA_0G01060
uniprot id: G8BVL5
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

1071381:TPHA 0A01610
gene id: 1071381:TPHA_0A01610
uniprot id: G8BMW6
names: Similarity
messages: Belongs to the dopey family.

1071381:TPHA 0C01690
gene id: 1071381:TPHA_0C01690
uniprot id: G8BRE9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1071381:TPHA 0K00500
gene id: 1071381:TPHA_0K00500
uniprot id: G8BZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

1071381:TPHA 0C03470
gene id: 1071381:TPHA_0C03470
uniprot id: G8BRX3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1071381:TPHA 0B01890
gene id: 1071381:TPHA_0B01890
uniprot id: G8BPD0
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

1071381:TPHA 0C03730
gene id: 1071381:TPHA_0C03730
uniprot id: G8BQL3
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071381:TPHA 0L02030
gene id: 1071381:TPHA_0L02030
uniprot id: G8C077
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

1071381:TPHA 0I01550
gene id: 1071381:TPHA_0I01550
uniprot id: G8BXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

1071381:TPHA 0B00420
gene id: 1071381:TPHA_0B00420
uniprot id: G8BQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A00180
gene id: 1071381:TPHA_0A00180
uniprot id: G8BMH5
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1071381:TPHA 0A00430
gene id: 1071381:TPHA_0A00430
uniprot id: G8BMK0
names: Similarity
messages: Belongs to the KRI1 family.

1071381:TPHA 0D03890
gene id: 1071381:TPHA_0D03890
uniprot id: G8BT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

1071381:TPHA 0O00460
gene id: 1071381:TPHA_0O00460
uniprot id: G8C1I9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1071381:TPHA 0B00330
gene id: 1071381:TPHA_0B00330
uniprot id: G8BQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

1071381:TPHA 0A04800
gene id: 1071381:TPHA_0A04800
uniprot id: G8BNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071381:TPHA 0C01980
gene id: 1071381:TPHA_0C01980
uniprot id: G8BRH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1071381:TPHA 0C03430
gene id: 1071381:TPHA_0C03430
uniprot id: G8BRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

1071381:TPHA 0B00810
gene id: 1071381:TPHA_0B00810
uniprot id: G8BQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E00410
gene id: 1071381:TPHA_0E00410
uniprot id: G8BTA9
names: Similarity
messages: Belongs to the peptidase M20A family.

1071381:TPHA 0J00430
gene id: 1071381:TPHA_0J00430
uniprot id: G8BYC4
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1071381:TPHA 0F03330
gene id: 1071381:TPHA_0F03330
uniprot id: G8BUM8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

1071381:TPHA 0F02960
gene id: 1071381:TPHA_0F02960
uniprot id: G8BUJ1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J00770
gene id: 1071381:TPHA_0J00770
uniprot id: G8BYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Mitochondrion

1071381:TPHA 0N01500
gene id: 1071381:TPHA_0N01500
uniprot id: G8C1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1071381:TPHA 0F02570
gene id: 1071381:TPHA_0F02570
uniprot id: G8BUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0H02470
gene id: 1071381:TPHA_0H02470
uniprot id: G8BWJ9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D00150
gene id: 1071381:TPHA_0D00150
uniprot id: G8BS38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

1071381:TPHA 0F03360
gene id: 1071381:TPHA_0F03360
uniprot id: G8BUN1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1071381:TPHA 0N01900
gene id: 1071381:TPHA_0N01900
uniprot id: G8C1E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0B00290
gene id: 1071381:TPHA_0B00290
uniprot id: G8BQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071381:TPHA 0C00370
gene id: 1071381:TPHA_0C00370
uniprot id: G8BR18
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071381:TPHA 0A05630
gene id: 1071381:TPHA_0A05630
uniprot id: G8BP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071381:TPHA 0E00760
gene id: 1071381:TPHA_0E00760
uniprot id: G8BTE3
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0G02250
gene id: 1071381:TPHA_0G02250
uniprot id: G8BVY3
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

1071381:TPHA 0D04240
gene id: 1071381:TPHA_0D04240
uniprot id: G8BRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

1071381:TPHA 0I01780
gene id: 1071381:TPHA_0I01780
uniprot id: G8BXQ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1071381:TPHA 0F01880
gene id: 1071381:TPHA_0F01880
uniprot id: G8BV88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1071381:TPHA 0A01210
gene id: 1071381:TPHA_0A01210
uniprot id: G8BMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

1071381:TPHA 0I01940
gene id: 1071381:TPHA_0I01940
uniprot id: G8BXS0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1071381:TPHA 0J01430
gene id: 1071381:TPHA_0J01430
uniprot id: G8BYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0K01060
gene id: 1071381:TPHA_0K01060
uniprot id: G8BZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

1071381:TPHA 0C00350
gene id: 1071381:TPHA_0C00350
uniprot id: G8BR16
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071381:TPHA 0G01970
gene id: 1071381:TPHA_0G01970
uniprot id: G8BVV5
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

1071381:TPHA 0A04670
gene id: 1071381:TPHA_0A04670
uniprot id: G8BNR2
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0M02150
gene id: 1071381:TPHA_0M02150
uniprot id: G8C0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

1071381:TPHA 0C03770
gene id: 1071381:TPHA_0C03770
uniprot id: G8BQL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

1071381:TPHA 0G03490
gene id: 1071381:TPHA_0G03490
uniprot id: G8BWB1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1071381:TPHA 0J02940
gene id: 1071381:TPHA_0J02940
uniprot id: G8BY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

1071381:TPHA 0C02550
gene id: 1071381:TPHA_0C02550
uniprot id: G8BRN2
names: Similarity
messages: Belongs to the NDK family.

1071381:TPHA 0D03500
gene id: 1071381:TPHA_0D03500
uniprot id: G8BT14
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1071381:TPHA 0K01360
gene id: 1071381:TPHA_0K01360
uniprot id: G8BZE1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0K01450
gene id: 1071381:TPHA_0K01450
uniprot id: G8BZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

1071381:TPHA 0L00580
gene id: 1071381:TPHA_0L00580
uniprot id: G8BZT6
names: Similarity
messages: Belongs to the OPI10 family.

1071381:TPHA 0F01740
gene id: 1071381:TPHA_0F01740
uniprot id: G8BV76
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

1071381:TPHA 0E02380
gene id: 1071381:TPHA_0E02380
uniprot id: G8BTV2
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1071381:TPHA 0I00740
gene id: 1071381:TPHA_0I00740
uniprot id: G8BXF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0A01040
gene id: 1071381:TPHA_0A01040
uniprot id: G8BMR1
names: Similarity
messages: Belongs to the NOC2 family.

1071381:TPHA 0N00690
gene id: 1071381:TPHA_0N00690
uniprot id: G8C122
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G02400
gene id: 1071381:TPHA_0G02400
uniprot id: G8BVZ7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1071381:TPHA 0N00580
gene id: 1071381:TPHA_0N00580
uniprot id: G8C111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

1071381:TPHA 0H00540
gene id: 1071381:TPHA_0H00540
uniprot id: G8BWW0
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071381:TPHA 0E03210
gene id: 1071381:TPHA_0E03210
uniprot id: G8BU33
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071381:TPHA 0M00650
gene id: 1071381:TPHA_0M00650
uniprot id: G8C0C5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1071381:TPHA 0D02070
gene id: 1071381:TPHA_0D02070
uniprot id: G8BSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

1071381:TPHA 0H00990
gene id: 1071381:TPHA_0H00990
uniprot id: G8BX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

1071381:TPHA 0I01390
gene id: 1071381:TPHA_0I01390
uniprot id: G8BXL7
names: Similarity
messages: Belongs to the Tom22 family.

1071381:TPHA 0B03910
gene id: 1071381:TPHA_0B03910
uniprot id: G8BPY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1071381:TPHA 0F03570
gene id: 1071381:TPHA_0F03570
uniprot id: G8BUQ1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

1071381:TPHA 0C02660
gene id: 1071381:TPHA_0C02660
uniprot id: G8BRP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0N01080
gene id: 1071381:TPHA_0N01080
uniprot id: G8C161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0B01410
gene id: 1071381:TPHA_0B01410
uniprot id: G8BP83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

1071381:TPHA 0D00420
gene id: 1071381:TPHA_0D00420
uniprot id: G8BS64
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071381:TPHA 0H03090
gene id: 1071381:TPHA_0H03090
uniprot id: G8BWR1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0G02430
gene id: 1071381:TPHA_0G02430
uniprot id: G8BW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

1071381:TPHA 0I01090
gene id: 1071381:TPHA_0I01090
uniprot id: G8BXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

1071381:TPHA 0D02370
gene id: 1071381:TPHA_0D02370
uniprot id: G8BSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

1071381:TPHA 0L01380
gene id: 1071381:TPHA_0L01380
uniprot id: G8C015
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1071381:TPHA 0E00420
gene id: 1071381:TPHA_0E00420
uniprot id: G8BTB0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E01170
gene id: 1071381:TPHA_0E01170
uniprot id: G8BTI3
names: Similarity
messages: Belongs to the XPC family.

1071381:TPHA 0G00540
gene id: 1071381:TPHA_0G00540
uniprot id: G8BVG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

1071381:TPHA 0P00520
gene id: 1071381:TPHA_0P00520
uniprot id: G8C232
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

1071381:TPHA 0A04350
gene id: 1071381:TPHA_0A04350
uniprot id: G8BNN1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

1071381:TPHA 0N00160
gene id: 1071381:TPHA_0N00160
uniprot id: G8C0W9
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1071381:TPHA 0M01860
gene id: 1071381:TPHA_0M01860
uniprot id: G8C0P6
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1071381:TPHA 0F03630
gene id: 1071381:TPHA_0F03630
uniprot id: G8BUQ7
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0I00840
gene id: 1071381:TPHA_0I00840
uniprot id: G8BXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

1071381:TPHA 0C00150
gene id: 1071381:TPHA_0C00150
uniprot id: G8BQZ6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A04770
gene id: 1071381:TPHA_0A04770
uniprot id: G8BNS4
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

1071381:TPHA 0B01950
gene id: 1071381:TPHA_0B01950
uniprot id: G8BPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

1071381:TPHA 0C03040
gene id: 1071381:TPHA_0C03040
uniprot id: G8BRT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1071381:TPHA 0D00940
gene id: 1071381:TPHA_0D00940
uniprot id: G8BSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

1071381:TPHA 0L01310
gene id: 1071381:TPHA_0L01310
uniprot id: G8C008
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

1071381:TPHA 0B02070
gene id: 1071381:TPHA_0B02070
uniprot id: G8BPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

1071381:TPHA 0A02670
gene id: 1071381:TPHA_0A02670
uniprot id: G8BN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1071381:TPHA 0C04340
gene id: 1071381:TPHA_0C04340
uniprot id: G8BQS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

1071381:TPHA 0A05710
gene id: 1071381:TPHA_0A05710
uniprot id: G8BP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

1071381:TPHA 0N00240
gene id: 1071381:TPHA_0N00240
uniprot id: G8C0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0A05760
gene id: 1071381:TPHA_0A05760
uniprot id: G8BP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

1071381:TPHA 0F03560
gene id: 1071381:TPHA_0F03560
uniprot id: G8BUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071381:TPHA 0I03200
gene id: 1071381:TPHA_0I03200
uniprot id: G8BY43
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0A00220
gene id: 1071381:TPHA_0A00220
uniprot id: G8BMH9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

1071381:TPHA 0N01420
gene id: 1071381:TPHA_0N01420
uniprot id: G8C195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

1071381:TPHA 0A06020
gene id: 1071381:TPHA_0A06020
uniprot id: G8BP48
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

1071381:TPHA 0O00750
gene id: 1071381:TPHA_0O00750
uniprot id: G8C1L6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

1071381:TPHA 0D00830
gene id: 1071381:TPHA_0D00830
uniprot id: G8BSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

1071381:TPHA 0D01720
gene id: 1071381:TPHA_0D01720
uniprot id: G8BSJ1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1071381:TPHA 0A02210
gene id: 1071381:TPHA_0A02210
uniprot id: G8BN25
names: Similarity
messages: Belongs to the SH3YL1 family.

1071381:TPHA 0P00300
gene id: 1071381:TPHA_0P00300
uniprot id: G8C210
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0B04130
gene id: 1071381:TPHA_0B04130
uniprot id: G8BQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0G02000
gene id: 1071381:TPHA_0G02000
uniprot id: G8BVV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSW5 family.
messages: Involved in spore wall assembly.
messages: Membrane

1071381:TPHA 0C02820
gene id: 1071381:TPHA_0C02820
uniprot id: G8BRQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1071381:TPHA 0A02870
gene id: 1071381:TPHA_0A02870
uniprot id: G8BN90
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

1071381:TPHA 0A02450
gene id: 1071381:TPHA_0A02450
uniprot id: G8BN50
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C04940
gene id: 1071381:TPHA_0C04940
uniprot id: G8BQY0
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

1071381:TPHA 0D03620
gene id: 1071381:TPHA_0D03620
uniprot id: G8BT26
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

1071381:TPHA 0O00980
gene id: 1071381:TPHA_0O00980
uniprot id: G8C1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

1071381:TPHA 0G02490
gene id: 1071381:TPHA_0G02490
uniprot id: G8BW06
names: Similarity
messages: Belongs to the SSH4 family.

1071381:TPHA 0C02730
gene id: 1071381:TPHA_0C02730
uniprot id: G8BRQ0
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

1071381:TPHA 0J00420
gene id: 1071381:TPHA_0J00420
uniprot id: G8BYC3
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

1071381:TPHA 0D03560
gene id: 1071381:TPHA_0D03560
uniprot id: G8BT20
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P00910
gene id: 1071381:TPHA_0P00910
uniprot id: G8C271
names: Similarity
messages: Belongs to the UPP synthase family.

1071381:TPHA 0I01810
gene id: 1071381:TPHA_0I01810
uniprot id: G8BXQ7
names: Similarity
messages: Belongs to the SEN54 family.

1071381:TPHA 0P01820
gene id: 1071381:TPHA_0P01820
uniprot id: G8C2G1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

1071381:TPHA 0M00940
gene id: 1071381:TPHA_0M00940
uniprot id: G8C0F4
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

1071381:TPHA 0F02890
gene id: 1071381:TPHA_0F02890
uniprot id: G8BUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: nuclear pore complex

1071381:TPHA 0P01520
gene id: 1071381:TPHA_0P01520
uniprot id: G8C2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

1071381:TPHA 0E04080
gene id: 1071381:TPHA_0E04080
uniprot id: G8BUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

1071381:TPHA 0D02250
gene id: 1071381:TPHA_0D02250
uniprot id: G8BSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1071381:TPHA 0J02740
gene id: 1071381:TPHA_0J02740
uniprot id: G8BZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0D00840
gene id: 1071381:TPHA_0D00840
uniprot id: G8BSA6
names: Similarity
messages: Belongs to the NEMF family.

1071381:TPHA 0M00500
gene id: 1071381:TPHA_0M00500
uniprot id: G8C0B0
names: Similarity
messages: Belongs to the RENT3 family.

1071381:TPHA 0E00610
gene id: 1071381:TPHA_0E00610
uniprot id: G8BTC8
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

1071381:TPHA 0I03170
gene id: 1071381:TPHA_0I03170
uniprot id: G8BY40
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E00690
gene id: 1071381:TPHA_0E00690
uniprot id: G8BTD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1071381:TPHA 0C01860
gene id: 1071381:TPHA_0C01860
uniprot id: G8BRG6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0C02280
gene id: 1071381:TPHA_0C02280
uniprot id: G8BRK5
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

1071381:TPHA 0K00590
gene id: 1071381:TPHA_0K00590
uniprot id: G8BZ65
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1071381:TPHA 0B02720
gene id: 1071381:TPHA_0B02720
uniprot id: G8BPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1071381:TPHA 0C01500
gene id: 1071381:TPHA_0C01500
uniprot id: G8BRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 22 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0C03400
gene id: 1071381:TPHA_0C03400
uniprot id: G8BRW6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1071381:TPHA 0I02030
gene id: 1071381:TPHA_0I02030
uniprot id: G8BXS9
names: Similarity
messages: Belongs to the PGA52 family.

1071381:TPHA 0J02520
gene id: 1071381:TPHA_0J02520
uniprot id: G8BYY0
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

1071381:TPHA 0N01670
gene id: 1071381:TPHA_0N01670
uniprot id: G8C1C0
names: Similarity
messages: Belongs to the SURF6 family.

1071381:TPHA 0K00260
gene id: 1071381:TPHA_0K00260
uniprot id: G8BZ32
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1071381:TPHA 0K00660
gene id: 1071381:TPHA_0K00660
uniprot id: G8BZ72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1071381:TPHA 0I02000
gene id: 1071381:TPHA_0I02000
uniprot id: G8BXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0K00490
gene id: 1071381:TPHA_0K00490
uniprot id: G8BZ55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1071381:TPHA 0I01950
gene id: 1071381:TPHA_0I01950
uniprot id: G8BXS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1071381:TPHA 0A03460
gene id: 1071381:TPHA_0A03460
uniprot id: G8BNE4
names: Subcellular Location Annotation
messages: Mitochondrion

1071381:TPHA 0M02160
gene id: 1071381:TPHA_0M02160
uniprot id: G8C0S5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0I01050
gene id: 1071381:TPHA_0I01050
uniprot id: G8BXI3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071381:TPHA 0C04790
gene id: 1071381:TPHA_0C04790
uniprot id: G8BQW6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0I02100
gene id: 1071381:TPHA_0I02100
uniprot id: G8BXT6
names: Similarity
messages: Belongs to the SEC3 family.

1071381:TPHA 0N01150
gene id: 1071381:TPHA_0N01150
uniprot id: G8C168
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D01980
gene id: 1071381:TPHA_0D01980
uniprot id: G8BSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

1071381:TPHA 0D04090
gene id: 1071381:TPHA_0D04090
uniprot id: G8BT71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0G01410
gene id: 1071381:TPHA_0G01410
uniprot id: G8BVQ0
names: Similarity
messages: Belongs to the EFR3 family.

1071381:TPHA 0D02040
gene id: 1071381:TPHA_0D02040
uniprot id: G8BSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

1071381:TPHA 0O01680
gene id: 1071381:TPHA_0O01680
uniprot id: G8C1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

1071381:TPHA 0I03290
gene id: 1071381:TPHA_0I03290
uniprot id: G8BY52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

1071381:TPHA 0D00930
gene id: 1071381:TPHA_0D00930
uniprot id: G8BSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

1071381:TPHA 0I00950
gene id: 1071381:TPHA_0I00950
uniprot id: G8BXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

1071381:TPHA 0M01460
gene id: 1071381:TPHA_0M01460
uniprot id: G8C0K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

1071381:TPHA 0F00860
gene id: 1071381:TPHA_0F00860
uniprot id: G8BUZ0
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071381:TPHA 0D00230
gene id: 1071381:TPHA_0D00230
uniprot id: G8BS46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

1071381:TPHA 0A04990
gene id: 1071381:TPHA_0A04990
uniprot id: G8BNU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071381:TPHA 0J02460
gene id: 1071381:TPHA_0J02460
uniprot id: G8BYX4
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

1071381:TPHA 0B03440
gene id: 1071381:TPHA_0B03440
uniprot id: G8BPT3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1071381:TPHA 0F02050
gene id: 1071381:TPHA_0F02050
uniprot id: G8BVA5
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

1071381:TPHA 0B04030
gene id: 1071381:TPHA_0B04030
uniprot id: G8BPZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

1071381:TPHA 0N01580
gene id: 1071381:TPHA_0N01580
uniprot id: G8C1B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

1071381:TPHA 0D02710
gene id: 1071381:TPHA_0D02710
uniprot id: G8BST6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071381:TPHA 0O00360
gene id: 1071381:TPHA_0O00360
uniprot id: G8C1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

1071381:TPHA 0A01600
gene id: 1071381:TPHA_0A01600
uniprot id: G8BMW5
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

1071381:TPHA 0A04190
gene id: 1071381:TPHA_0A04190
uniprot id: G8BNL6
names: Similarity
messages: Belongs to the SCO1/2 family.

1071381:TPHA 0F02290
gene id: 1071381:TPHA_0F02290
uniprot id: G8BUC4
names: Similarity
messages: Belongs to the APC1 family.

1071381:TPHA 0H01200
gene id: 1071381:TPHA_0H01200
uniprot id: G8BX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1071381:TPHA 0O00250
gene id: 1071381:TPHA_0O00250
uniprot id: G8C1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0H00940
gene id: 1071381:TPHA_0H00940
uniprot id: G8BWZ8
names: Similarity
messages: Belongs to the thioredoxin family.

1071381:TPHA 0O01450
gene id: 1071381:TPHA_0O01450
uniprot id: G8C1T4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0D03020
gene id: 1071381:TPHA_0D03020
uniprot id: G8BSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0H02580
gene id: 1071381:TPHA_0H02580
uniprot id: G8BWL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071381:TPHA 0F01870
gene id: 1071381:TPHA_0F01870
uniprot id: G8BV87
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

1071381:TPHA 0B04660
gene id: 1071381:TPHA_0B04660
uniprot id: G8BQ54
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1071381:TPHA 0G01110
gene id: 1071381:TPHA_0G01110
uniprot id: G8BVM0
names: Similarity
messages: Belongs to the SUN family.

1071381:TPHA 0K00940
gene id: 1071381:TPHA_0K00940
uniprot id: G8BZA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

1071381:TPHA 0K01130
gene id: 1071381:TPHA_0K01130
uniprot id: G8BZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1071381:TPHA 0L02340
gene id: 1071381:TPHA_0L02340
uniprot id: G8C0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

1071381:TPHA 0A02000
gene id: 1071381:TPHA_0A02000
uniprot id: G8BN04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071381:TPHA 0M00750
gene id: 1071381:TPHA_0M00750
uniprot id: G8C0D5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0H03120
gene id: 1071381:TPHA_0H03120
uniprot id: G8BWR4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071381:TPHA 0C02470
gene id: 1071381:TPHA_0C02470
uniprot id: G8BRM4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1071381:TPHA 0A04820
gene id: 1071381:TPHA_0A04820
uniprot id: G8BNS9
names: Similarity
messages: Belongs to the IlvD/Edd family.

1071381:TPHA 0G02730
gene id: 1071381:TPHA_0G02730
uniprot id: G8BW32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

1071381:TPHA 0N00340
gene id: 1071381:TPHA_0N00340
uniprot id: G8C0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F01620
gene id: 1071381:TPHA_0F01620
uniprot id: G8BV64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

1071381:TPHA 0F01500
gene id: 1071381:TPHA_0F01500
uniprot id: G8BV52
names: Similarity
messages: Belongs to the MAD2 family.

1071381:TPHA 0B04690
gene id: 1071381:TPHA_0B04690
uniprot id: G8BQ57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1071381:TPHA 0A01450
gene id: 1071381:TPHA_0A01450
uniprot id: G8BMV0
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

1071381:TPHA 0A05360
gene id: 1071381:TPHA_0A05360
uniprot id: G8BNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0C02650
gene id: 1071381:TPHA_0C02650
uniprot id: G8BRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation.
messages: telomere

1071381:TPHA 0F01580
gene id: 1071381:TPHA_0F01580
uniprot id: G8BV60
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F02100
gene id: 1071381:TPHA_0F02100
uniprot id: G8BVB0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071381:TPHA 0C02340
gene id: 1071381:TPHA_0C02340
uniprot id: G8BRL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071381:TPHA 0B02840
gene id: 1071381:TPHA_0B02840
uniprot id: G8BPM5
names: Similarity
messages: Belongs to the NOC2 family.

1071381:TPHA 0E01930
gene id: 1071381:TPHA_0E01930
uniprot id: G8BTQ7
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0L01470
gene id: 1071381:TPHA_0L01470
uniprot id: G8C024
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0G01520
gene id: 1071381:TPHA_0G01520
uniprot id: G8BVR0
names: Similarity
messages: Belongs to the TMA16 family.

1071381:TPHA 0C02850
gene id: 1071381:TPHA_0C02850
uniprot id: G8BRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

1071381:TPHA 0C04010
gene id: 1071381:TPHA_0C04010
uniprot id: G8BQN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

1071381:TPHA 0E02950
gene id: 1071381:TPHA_0E02950
uniprot id: G8BU07
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

1071381:TPHA 0I03310
gene id: 1071381:TPHA_0I03310
uniprot id: G8BY54
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0F01000
gene id: 1071381:TPHA_0F01000
uniprot id: G8BV04
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

1071381:TPHA 0K00190
gene id: 1071381:TPHA_0K00190
uniprot id: G8BZ25
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1071381:TPHA 0E02990
gene id: 1071381:TPHA_0E02990
uniprot id: G8BU11
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071381:TPHA 0K01350
gene id: 1071381:TPHA_0K01350
uniprot id: G8BZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

1071381:TPHA 0H01490
gene id: 1071381:TPHA_0H01490
uniprot id: G8BX51
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

1071381:TPHA 0M01650
gene id: 1071381:TPHA_0M01650
uniprot id: G8C0M5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1071381:TPHA 0D03830
gene id: 1071381:TPHA_0D03830
uniprot id: G8BT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

1071381:TPHA 0B03310
gene id: 1071381:TPHA_0B03310
uniprot id: G8BPS2
names: Similarity
messages: Belongs to the 14-3-3 family.

1071381:TPHA 0E03480
gene id: 1071381:TPHA_0E03480
uniprot id: G8BU60
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0G01390
gene id: 1071381:TPHA_0G01390
uniprot id: G8BVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

1071381:TPHA 0D00220
gene id: 1071381:TPHA_0D00220
uniprot id: G8BS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071381:TPHA 0G02860
gene id: 1071381:TPHA_0G02860
uniprot id: G8BW46
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1071381:TPHA 0L01820
gene id: 1071381:TPHA_0L01820
uniprot id: G8C057
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0P00620
gene id: 1071381:TPHA_0P00620
uniprot id: G8C242
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1071381:TPHA 0G03360
gene id: 1071381:TPHA_0G03360
uniprot id: G8BW98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

1071381:TPHA 0J00710
gene id: 1071381:TPHA_0J00710
uniprot id: G8BYF2
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

1071381:TPHA 0F03460
gene id: 1071381:TPHA_0F03460
uniprot id: G8BUP0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0I02470
gene id: 1071381:TPHA_0I02470
uniprot id: G8BXX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1071381:TPHA 0F00690
gene id: 1071381:TPHA_0F00690
uniprot id: G8BUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1071381:TPHA 0J01550
gene id: 1071381:TPHA_0J01550
uniprot id: G8BYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

1071381:TPHA 0H01450
gene id: 1071381:TPHA_0H01450
uniprot id: G8BX47
names: Similarity
messages: Belongs to the PP2C family.

1071381:TPHA 0G00470
gene id: 1071381:TPHA_0G00470
uniprot id: G8BVF5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

1071381:TPHA 0D03920
gene id: 1071381:TPHA_0D03920
uniprot id: G8BT54
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1071381:TPHA 0C00120
gene id: 1071381:TPHA_0C00120
uniprot id: G8BQZ3
names: Similarity
messages: Belongs to the GST superfamily.

1071381:TPHA 0L01990
gene id: 1071381:TPHA_0L01990
uniprot id: G8C073
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071381:TPHA 0N01920
gene id: 1071381:TPHA_0N01920
uniprot id: G8C1E5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

1071381:TPHA 0H01030
gene id: 1071381:TPHA_0H01030
uniprot id: G8BX07
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

1071381:TPHA 0J01600
gene id: 1071381:TPHA_0J01600
uniprot id: G8BYN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

1071381:TPHA 0F00700
gene id: 1071381:TPHA_0F00700
uniprot id: G8BUX4
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0K01660
gene id: 1071381:TPHA_0K01660
uniprot id: G8BZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1071381:TPHA 0D01730
gene id: 1071381:TPHA_0D01730
uniprot id: G8BSJ2
names: Similarity
messages: Belongs to the glutaredoxin family.

1071381:TPHA 0K00780
gene id: 1071381:TPHA_0K00780
uniprot id: G8BZ84
names: Similarity
messages: Belongs to the WD repeat rae1 family.

1071381:TPHA 0B04300
gene id: 1071381:TPHA_0B04300
uniprot id: G8BQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0A05800
gene id: 1071381:TPHA_0A05800
uniprot id: G8BP26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

1071381:TPHA 0E01010
gene id: 1071381:TPHA_0E01010
uniprot id: G8BTG7
names: Similarity
messages: Belongs to the PP2C family.

1071381:TPHA 0J00470
gene id: 1071381:TPHA_0J00470
uniprot id: G8BYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

1071381:TPHA 0D03060
gene id: 1071381:TPHA_0D03060
uniprot id: G8BSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0H00340
gene id: 1071381:TPHA_0H00340
uniprot id: G8BWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B02560
gene id: 1071381:TPHA_0B02560
uniprot id: G8BPJ8
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

1071381:TPHA 0A02650
gene id: 1071381:TPHA_0A02650
uniprot id: G8BN69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

1071381:TPHA 0K00620
gene id: 1071381:TPHA_0K00620
uniprot id: G8BZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

1071381:TPHA 0H02960
gene id: 1071381:TPHA_0H02960
uniprot id: G8BWP8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071381:TPHA 0C00830
gene id: 1071381:TPHA_0C00830
uniprot id: G8BR63
names: Similarity
messages: Belongs to the cullin family.

1071381:TPHA 0G01670
gene id: 1071381:TPHA_0G01670
uniprot id: G8BVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071381:TPHA 0C01640
gene id: 1071381:TPHA_0C01640
uniprot id: G8BRE4
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0J01710
gene id: 1071381:TPHA_0J01710
uniprot id: G8BYQ0
names: Similarity
messages: Belongs to the SAS10 family.

1071381:TPHA 0J00850
gene id: 1071381:TPHA_0J00850
uniprot id: G8BYG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1071381:TPHA 0A05130
gene id: 1071381:TPHA_0A05130
uniprot id: G8BNW0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071381:TPHA 0C04510
gene id: 1071381:TPHA_0C04510
uniprot id: G8BQU0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

1071381:TPHA 0O00780
gene id: 1071381:TPHA_0O00780
uniprot id: G8C1L9
names: Similarity
messages: Belongs to the OMP decarboxylase family.

1071381:TPHA 0O01950
gene id: 1071381:TPHA_0O01950
uniprot id: G8C1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

1071381:TPHA 0L01780
gene id: 1071381:TPHA_0L01780
uniprot id: G8C053
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071381:TPHA 0N00500
gene id: 1071381:TPHA_0N00500
uniprot id: G8C102
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1071381:TPHA 0H00660
gene id: 1071381:TPHA_0H00660
uniprot id: G8BWX2
names: Similarity
messages: Belongs to the TCP11 family.

1071381:TPHA 0K00230
gene id: 1071381:TPHA_0K00230
uniprot id: G8BZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

1071381:TPHA 0D02260
gene id: 1071381:TPHA_0D02260
uniprot id: G8BSP3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0B00340
gene id: 1071381:TPHA_0B00340
uniprot id: G8BQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

1071381:TPHA 0H02890
gene id: 1071381:TPHA_0H02890
uniprot id: G8BWP1
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0E02820
gene id: 1071381:TPHA_0E02820
uniprot id: G8BTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

1071381:TPHA 0C03530
gene id: 1071381:TPHA_0C03530
uniprot id: G8BQJ3
names: Similarity
messages: Belongs to the frataxin family.

1071381:TPHA 0A02460
gene id: 1071381:TPHA_0A02460
uniprot id: G8BN51
names: Similarity
messages: Belongs to the CCZ1 family.

1071381:TPHA 0D04260
gene id: 1071381:TPHA_0D04260
uniprot id: G8BRY5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0H00810
gene id: 1071381:TPHA_0H00810
uniprot id: G8BWY6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1071381:TPHA 0B01250
gene id: 1071381:TPHA_0B01250
uniprot id: G8BP67
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0F00180
gene id: 1071381:TPHA_0F00180
uniprot id: G8BUS3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B02040
gene id: 1071381:TPHA_0B02040
uniprot id: G8BPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

1071381:TPHA 0B02340
gene id: 1071381:TPHA_0B02340
uniprot id: G8BPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

1071381:TPHA 0B03460
gene id: 1071381:TPHA_0B03460
uniprot id: G8BPT5
names: Similarity
messages: Belongs to the SPT2 family.

1071381:TPHA 0M01700
gene id: 1071381:TPHA_0M01700
uniprot id: G8C0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0C01290
gene id: 1071381:TPHA_0C01290
uniprot id: G8BRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0I00970
gene id: 1071381:TPHA_0I00970
uniprot id: G8BXH5
names: Similarity
messages: Belongs to the TRL1 family.

1071381:TPHA 0D04290
gene id: 1071381:TPHA_0D04290
uniprot id: G8BRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

1071381:TPHA 0F01310
gene id: 1071381:TPHA_0F01310
uniprot id: G8BV34
names: Similarity
messages: Belongs to the SUN family.

1071381:TPHA 0G02875
gene id: 1071381:TPHA_0G02875
uniprot id: G8BW49
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071381:TPHA 0A00800
gene id: 1071381:TPHA_0A00800
uniprot id: G8BMN7
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

1071381:TPHA 0A00230
gene id: 1071381:TPHA_0A00230
uniprot id: G8BMI0
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1071381:TPHA 0K00220
gene id: 1071381:TPHA_0K00220
uniprot id: G8BZ28
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G02410
gene id: 1071381:TPHA_0G02410
uniprot id: G8BVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE2 family.
messages: Nucleus

1071381:TPHA 0G00940
gene id: 1071381:TPHA_0G00940
uniprot id: G8BVK2
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071381:TPHA 0L00820
gene id: 1071381:TPHA_0L00820
uniprot id: G8BZW1
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0O01480
gene id: 1071381:TPHA_0O01480
uniprot id: G8C1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Membrane

1071381:TPHA 0F03590
gene id: 1071381:TPHA_0F03590
uniprot id: G8BUQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0J01240
gene id: 1071381:TPHA_0J01240
uniprot id: G8BYK4
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

1071381:TPHA 0A05240
gene id: 1071381:TPHA_0A05240
uniprot id: G8BNX1
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1071381:TPHA 0P01620
gene id: 1071381:TPHA_0P01620
uniprot id: G8C2E2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0I02300
gene id: 1071381:TPHA_0I02300
uniprot id: G8BXV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

1071381:TPHA 0A00470
gene id: 1071381:TPHA_0A00470
uniprot id: G8BMK4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

1071381:TPHA 0B02150
gene id: 1071381:TPHA_0B02150
uniprot id: G8BPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

1071381:TPHA 0C00130
gene id: 1071381:TPHA_0C00130
uniprot id: G8BQZ4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0E03350
gene id: 1071381:TPHA_0E03350
uniprot id: G8BU47
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A00210
gene id: 1071381:TPHA_0A00210
uniprot id: G8BMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A03300
gene id: 1071381:TPHA_0A03300
uniprot id: G8BNC9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071381:TPHA 0L00170
gene id: 1071381:TPHA_0L00170
uniprot id: G8BZP6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1071381:TPHA 0I00250
gene id: 1071381:TPHA_0I00250
uniprot id: G8BXA4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1071381:TPHA 0P01350
gene id: 1071381:TPHA_0P01350
uniprot id: G8C2B5
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071381:TPHA 0H02940
gene id: 1071381:TPHA_0H02940
uniprot id: G8BWP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

1071381:TPHA 0E01880
gene id: 1071381:TPHA_0E01880
uniprot id: G8BTQ3
names: Subcellular Location Annotation
messages: Golgi apparatus

1071381:TPHA 0G01140
gene id: 1071381:TPHA_0G01140
uniprot id: G8BVM3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

1071381:TPHA 0N01630
gene id: 1071381:TPHA_0N01630
uniprot id: G8C1B6
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E02160
gene id: 1071381:TPHA_0E02160
uniprot id: G8BTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

1071381:TPHA 0G01950
gene id: 1071381:TPHA_0G01950
uniprot id: G8BVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0G00680
gene id: 1071381:TPHA_0G00680
uniprot id: G8BVH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0N01050
gene id: 1071381:TPHA_0N01050
uniprot id: G8C158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0L01760
gene id: 1071381:TPHA_0L01760
uniprot id: G8C051
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1071381:TPHA 0D00860
gene id: 1071381:TPHA_0D00860
uniprot id: G8BSA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

1071381:TPHA 0D02130
gene id: 1071381:TPHA_0D02130
uniprot id: G8BSN0
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0F01680
gene id: 1071381:TPHA_0F01680
uniprot id: G8BV70
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1071381:TPHA 0L00130
gene id: 1071381:TPHA_0L00130
uniprot id: G8BZP4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N00510
gene id: 1071381:TPHA_0N00510
uniprot id: G8C103
names: Subcellular Location Annotation
messages: Mitochondrion

1071381:TPHA 0C02530
gene id: 1071381:TPHA_0C02530
uniprot id: G8BRN0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0B01520
gene id: 1071381:TPHA_0B01520
uniprot id: G8BP94
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

1071381:TPHA 0C00920
gene id: 1071381:TPHA_0C00920
uniprot id: G8BR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

1071381:TPHA 0H02500
gene id: 1071381:TPHA_0H02500
uniprot id: G8BWK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0O00680
gene id: 1071381:TPHA_0O00680
uniprot id: G8C1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

1071381:TPHA 0M01980
gene id: 1071381:TPHA_0M01980
uniprot id: G8C0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

1071381:TPHA 0A01290
gene id: 1071381:TPHA_0A01290
uniprot id: G8BMT5
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

1071381:TPHA 0K01180
gene id: 1071381:TPHA_0K01180
uniprot id: G8BZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

1071381:TPHA 0A04810
gene id: 1071381:TPHA_0A04810
uniprot id: G8BNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0J02420
gene id: 1071381:TPHA_0J02420
uniprot id: G8BYX0
names: Similarity
messages: Belongs to the TYW1 family.

1071381:TPHA 0I00110
gene id: 1071381:TPHA_0I00110
uniprot id: G8BX90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

1071381:TPHA 0E02090
gene id: 1071381:TPHA_0E02090
uniprot id: G8BTS3
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1071381:TPHA 0K00760
gene id: 1071381:TPHA_0K00760
uniprot id: G8BZ82
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0M01580
gene id: 1071381:TPHA_0M01580
uniprot id: G8C0L8
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

1071381:TPHA 0O00380
gene id: 1071381:TPHA_0O00380
uniprot id: G8C1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

1071381:TPHA 0N00950
gene id: 1071381:TPHA_0N00950
uniprot id: G8C148
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0I01380
gene id: 1071381:TPHA_0I01380
uniprot id: G8BXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

1071381:TPHA 0G02880
gene id: 1071381:TPHA_0G02880
uniprot id: G8BW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

1071381:TPHA 0A05410
gene id: 1071381:TPHA_0A05410
uniprot id: G8BNY7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1071381:TPHA 0K00790
gene id: 1071381:TPHA_0K00790
uniprot id: G8BZ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071381:TPHA 0J01520
gene id: 1071381:TPHA_0J01520
uniprot id: G8BYN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0F02790
gene id: 1071381:TPHA_0F02790
uniprot id: G8BUH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071381:TPHA 0B02580
gene id: 1071381:TPHA_0B02580
uniprot id: G8BPK0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0P01800
gene id: 1071381:TPHA_0P01800
uniprot id: G8C2F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

1071381:TPHA 0D04110
gene id: 1071381:TPHA_0D04110
uniprot id: G8BT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

1071381:TPHA 0G02360
gene id: 1071381:TPHA_0G02360
uniprot id: G8BVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071381:TPHA 0O00820
gene id: 1071381:TPHA_0O00820
uniprot id: G8C1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

1071381:TPHA 0H00410
gene id: 1071381:TPHA_0H00410
uniprot id: G8BWU7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

1071381:TPHA 0G00660
gene id: 1071381:TPHA_0G00660
uniprot id: G8BVH4
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

1071381:TPHA 0B01930
gene id: 1071381:TPHA_0B01930
uniprot id: G8BPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

1071381:TPHA 0I03070
gene id: 1071381:TPHA_0I03070
uniprot id: G8BY30
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1071381:TPHA 0B00580
gene id: 1071381:TPHA_0B00580
uniprot id: G8BQD3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1071381:TPHA 0C00480
gene id: 1071381:TPHA_0C00480
uniprot id: G8BR29
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071381:TPHA 0P00240
gene id: 1071381:TPHA_0P00240
uniprot id: G8C204
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071381:TPHA 0P00390
gene id: 1071381:TPHA_0P00390
uniprot id: G8C219
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

1071381:TPHA 0F02440
gene id: 1071381:TPHA_0F02440
uniprot id: G8BUD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0D02280
gene id: 1071381:TPHA_0D02280
uniprot id: G8BSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

1071381:TPHA 0B02440
gene id: 1071381:TPHA_0B02440
uniprot id: G8BPI6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071381:TPHA 0C03420
gene id: 1071381:TPHA_0C03420
uniprot id: G8BRW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

1071381:TPHA 0P00880
gene id: 1071381:TPHA_0P00880
uniprot id: G8C268
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0E02700
gene id: 1071381:TPHA_0E02700
uniprot id: G8BTY3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D03930
gene id: 1071381:TPHA_0D03930
uniprot id: G8BT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

1071381:TPHA 0D03220
gene id: 1071381:TPHA_0D03220
uniprot id: G8BSY7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

1071381:TPHA 0D03550
gene id: 1071381:TPHA_0D03550
uniprot id: G8BT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Cytoplasm
messages: nucleolus

1071381:TPHA 0B02530
gene id: 1071381:TPHA_0B02530
uniprot id: G8BPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0A00840
gene id: 1071381:TPHA_0A00840
uniprot id: G8BMP1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E01570
gene id: 1071381:TPHA_0E01570
uniprot id: G8BTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0B01490
gene id: 1071381:TPHA_0B01490
uniprot id: G8BP91
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0E03370
gene id: 1071381:TPHA_0E03370
uniprot id: G8BU49
names: Similarity
messages: Belongs to the PGA52 family.

1071381:TPHA 0F01360
gene id: 1071381:TPHA_0F01360
uniprot id: G8BV39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

1071381:TPHA 0A01060
gene id: 1071381:TPHA_0A01060
uniprot id: G8BMR3
names: Similarity
messages: Belongs to the beclin family.

1071381:TPHA 0A03390
gene id: 1071381:TPHA_0A03390
uniprot id: G8BND8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

1071381:TPHA 0I01800
gene id: 1071381:TPHA_0I01800
uniprot id: G8BXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

1071381:TPHA 0F00440
gene id: 1071381:TPHA_0F00440
uniprot id: G8BUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

1071381:TPHA 0H02230
gene id: 1071381:TPHA_0H02230
uniprot id: G8BWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

1071381:TPHA 0H02530
gene id: 1071381:TPHA_0H02530
uniprot id: G8BWK5
names: Similarity
messages: Belongs to the TOP6A family.

1071381:TPHA 0N00600
gene id: 1071381:TPHA_0N00600
uniprot id: G8C113
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

1071381:TPHA 0L01250
gene id: 1071381:TPHA_0L01250
uniprot id: G8C004
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1071381:TPHA 0P00900
gene id: 1071381:TPHA_0P00900
uniprot id: G8C270
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

1071381:TPHA 0N01430
gene id: 1071381:TPHA_0N01430
uniprot id: G8C196
names: Similarity
messages: Belongs to the actin family.

1071381:TPHA 0M00550
gene id: 1071381:TPHA_0M00550
uniprot id: G8C0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

1071381:TPHA 0F00470
gene id: 1071381:TPHA_0F00470
uniprot id: G8BUV2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A03200
gene id: 1071381:TPHA_0A03200
uniprot id: G8BNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

1071381:TPHA 0O00140
gene id: 1071381:TPHA_0O00140
uniprot id: G8C1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0A01870
gene id: 1071381:TPHA_0A01870
uniprot id: G8BMZ2
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

1071381:TPHA 0A03570
gene id: 1071381:TPHA_0A03570
uniprot id: G8BNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

1071381:TPHA 0A01130
gene id: 1071381:TPHA_0A01130
uniprot id: G8BMR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

1071381:TPHA 0H01930
gene id: 1071381:TPHA_0H01930
uniprot id: G8BWE7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1071381:TPHA 0J02610
gene id: 1071381:TPHA_0J02610
uniprot id: G8BYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

1071381:TPHA 0D01640
gene id: 1071381:TPHA_0D01640
uniprot id: G8BSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

1071381:TPHA 0E00830
gene id: 1071381:TPHA_0E00830
uniprot id: G8BTF0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0G02740
gene id: 1071381:TPHA_0G02740
uniprot id: G8BW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

1071381:TPHA 0M00270
gene id: 1071381:TPHA_0M00270
uniprot id: G8C0U3
names: Similarity
messages: Belongs to the SGT family.

1071381:TPHA 0D03380
gene id: 1071381:TPHA_0D03380
uniprot id: G8BT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

1071381:TPHA 0G00450
gene id: 1071381:TPHA_0G00450
uniprot id: G8BVF3
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0K00930
gene id: 1071381:TPHA_0K00930
uniprot id: G8BZ99
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1071381:TPHA 0H01330
gene id: 1071381:TPHA_0H01330
uniprot id: G8BX36
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0C04460
gene id: 1071381:TPHA_0C04460
uniprot id: G8BQT5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

1071381:TPHA 0O00220
gene id: 1071381:TPHA_0O00220
uniprot id: G8C1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

1071381:TPHA 0H02170
gene id: 1071381:TPHA_0H02170
uniprot id: G8BWH0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J01690
gene id: 1071381:TPHA_0J01690
uniprot id: G8BYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

1071381:TPHA 0D04500
gene id: 1071381:TPHA_0D04500
uniprot id: G8BS09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

1071381:TPHA 0H02950
gene id: 1071381:TPHA_0H02950
uniprot id: G8BWP7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

1071381:TPHA 0A05660
gene id: 1071381:TPHA_0A05660
uniprot id: G8BP12
names: Similarity
messages: Belongs to the ELP6 family.

1071381:TPHA 0K00850
gene id: 1071381:TPHA_0K00850
uniprot id: G8BZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

1071381:TPHA 0J02820
gene id: 1071381:TPHA_0J02820
uniprot id: G8BZ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.

1071381:TPHA 0M01850
gene id: 1071381:TPHA_0M01850
uniprot id: G8C0P5
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0G00980
gene id: 1071381:TPHA_0G00980
uniprot id: G8BVK6
names: Subcellular Location Annotation
messages: nuclear pore complex

1071381:TPHA 0D04040
gene id: 1071381:TPHA_0D04040
uniprot id: G8BT66
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0K01640
gene id: 1071381:TPHA_0K01640
uniprot id: G8BZG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1071381:TPHA 0J02850
gene id: 1071381:TPHA_0J02850
uniprot id: G8BZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

1071381:TPHA 0D01710
gene id: 1071381:TPHA_0D01710
uniprot id: G8BSJ0
names: Similarity
messages: Belongs to the RMD1/sif2 family.

1071381:TPHA 0G02960
gene id: 1071381:TPHA_0G02960
uniprot id: G8BW59
names: Similarity
messages: Belongs to the MUB1/samB family.

1071381:TPHA 0D04080
gene id: 1071381:TPHA_0D04080
uniprot id: G8BT70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

1071381:TPHA 0C01990
gene id: 1071381:TPHA_0C01990
uniprot id: G8BRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

1071381:TPHA 0A03760
gene id: 1071381:TPHA_0A03760
uniprot id: G8BNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

1071381:TPHA 0A00290
gene id: 1071381:TPHA_0A00290
uniprot id: G8BMI6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1071381:TPHA 0B04460
gene id: 1071381:TPHA_0B04460
uniprot id: G8BQ34
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071381:TPHA 0J01300
gene id: 1071381:TPHA_0J01300
uniprot id: G8BYL0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

1071381:TPHA 0M00710
gene id: 1071381:TPHA_0M00710
uniprot id: G8C0D1
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

1071381:TPHA 0K00580
gene id: 1071381:TPHA_0K00580
uniprot id: G8BZ64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0I03020
gene id: 1071381:TPHA_0I03020
uniprot id: G8BY25
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01210
gene id: 1071381:TPHA_0C01210
uniprot id: G8BRA1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071381:TPHA 0K01720
gene id: 1071381:TPHA_0K01720
uniprot id: G8BZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0D03490
gene id: 1071381:TPHA_0D03490
uniprot id: G8BT13
names: Similarity
messages: Belongs to the BolA/IbaG family.

1071381:TPHA 0K00570
gene id: 1071381:TPHA_0K00570
uniprot id: G8BZ63
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

1071381:TPHA 0F03230
gene id: 1071381:TPHA_0F03230
uniprot id: G8BUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

1071381:TPHA 0O01800
gene id: 1071381:TPHA_0O01800
uniprot id: G8C1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

1071381:TPHA 0D04700
gene id: 1071381:TPHA_0D04700
uniprot id: G8BS28
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0O01420
gene id: 1071381:TPHA_0O01420
uniprot id: G8C1T1
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1071381:TPHA 0M01620
gene id: 1071381:TPHA_0M01620
uniprot id: G8C0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

1071381:TPHA 0C00960
gene id: 1071381:TPHA_0C00960
uniprot id: G8BR76
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A04707
gene id: 1071381:TPHA_0A04707
uniprot id: G8BNR7
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1071381:TPHA 0E02960
gene id: 1071381:TPHA_0E02960
uniprot id: G8BU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

1071381:TPHA 0H02690
gene id: 1071381:TPHA_0H02690
uniprot id: G8BWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

1071381:TPHA 0C00190
gene id: 1071381:TPHA_0C00190
uniprot id: G8BR00
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

1071381:TPHA 0D04220
gene id: 1071381:TPHA_0D04220
uniprot id: G8BRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

1071381:TPHA 0F02720
gene id: 1071381:TPHA_0F02720
uniprot id: G8BUG6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1071381:TPHA 0A04520
gene id: 1071381:TPHA_0A04520
uniprot id: G8BNP7
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1071381:TPHA 0C03230
gene id: 1071381:TPHA_0C03230
uniprot id: G8BRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

1071381:TPHA 0A04980
gene id: 1071381:TPHA_0A04980
uniprot id: G8BNU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1071381:TPHA 0G00490
gene id: 1071381:TPHA_0G00490
uniprot id: G8BVF7
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C00290
gene id: 1071381:TPHA_0C00290
uniprot id: G8BR10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1071381:TPHA 0L01000
gene id: 1071381:TPHA_0L01000
uniprot id: G8BZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Membrane

1071381:TPHA 0F00120
gene id: 1071381:TPHA_0F00120
uniprot id: G8BUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

1071381:TPHA 0F00620
gene id: 1071381:TPHA_0F00620
uniprot id: G8BUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

1071381:TPHA 0E03570
gene id: 1071381:TPHA_0E03570
uniprot id: G8BU69
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A03770
gene id: 1071381:TPHA_0A03770
uniprot id: G8BNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

1071381:TPHA 0G01370
gene id: 1071381:TPHA_0G01370
uniprot id: G8BVP6
names: Subunit
messages: Homodimer.

1071381:TPHA 0I00590
gene id: 1071381:TPHA_0I00590
uniprot id: G8BXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

1071381:TPHA 0N01240
gene id: 1071381:TPHA_0N01240
uniprot id: G8C177
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

1071381:TPHA 0A04490
gene id: 1071381:TPHA_0A04490
uniprot id: G8BNP4
names: Similarity
messages: Belongs to the UPF0045 family.

1071381:TPHA 0J00280
gene id: 1071381:TPHA_0J00280
uniprot id: G8BYB0
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0B03160
gene id: 1071381:TPHA_0B03160
uniprot id: G8BPQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

1071381:TPHA 0F00330
gene id: 1071381:TPHA_0F00330
uniprot id: G8BUT8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0K00990
gene id: 1071381:TPHA_0K00990
uniprot id: G8BZA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071381:TPHA 0B03730
gene id: 1071381:TPHA_0B03730
uniprot id: G8BPW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1071381:TPHA 0I02490
gene id: 1071381:TPHA_0I02490
uniprot id: G8BXX4
names: Function
names: Similarity
messages: Belongs to the BLI1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.

1071381:TPHA 0A03370
gene id: 1071381:TPHA_0A03370
uniprot id: G8BND6
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

1071381:TPHA 0A04590
gene id: 1071381:TPHA_0A04590
uniprot id: G8BNQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.

1071381:TPHA 0B03170
gene id: 1071381:TPHA_0B03170
uniprot id: G8BPQ8
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

1071381:TPHA 0L01130
gene id: 1071381:TPHA_0L01130
uniprot id: G8BZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

1071381:TPHA 0B00600
gene id: 1071381:TPHA_0B00600
uniprot id: G8BQD5
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0D01990
gene id: 1071381:TPHA_0D01990
uniprot id: G8BSL6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

1071381:TPHA 0I01610
gene id: 1071381:TPHA_0I01610
uniprot id: G8BXN7
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

1071381:TPHA 0B03780
gene id: 1071381:TPHA_0B03780
uniprot id: G8BPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0H02160
gene id: 1071381:TPHA_0H02160
uniprot id: G8BWG9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0B01050
gene id: 1071381:TPHA_0B01050
uniprot id: G8BQI0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0F00170
gene id: 1071381:TPHA_0F00170
uniprot id: G8BUS2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A00620
gene id: 1071381:TPHA_0A00620
uniprot id: G8BML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0H01180
gene id: 1071381:TPHA_0H01180
uniprot id: G8BX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

1071381:TPHA 0D03210
gene id: 1071381:TPHA_0D03210
uniprot id: G8BSY6
names: Similarity
messages: Belongs to the RRP15 family.

1071381:TPHA 0H00330
gene id: 1071381:TPHA_0H00330
uniprot id: G8BWT9
names: Similarity
messages: Belongs to the MT-A70-like family.

1071381:TPHA 0L01590
gene id: 1071381:TPHA_0L01590
uniprot id: G8C034
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0C01840
gene id: 1071381:TPHA_0C01840
uniprot id: G8BRG4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1071381:TPHA 0P01400
gene id: 1071381:TPHA_0P01400
uniprot id: G8C2C0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0E01310
gene id: 1071381:TPHA_0E01310
uniprot id: G8BTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0A01800
gene id: 1071381:TPHA_0A01800
uniprot id: G8BMY5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1071381:TPHA 0H01970
gene id: 1071381:TPHA_0H01970
uniprot id: G8BWF1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1071381:TPHA 0C01850
gene id: 1071381:TPHA_0C01850
uniprot id: G8BRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

1071381:TPHA 0E00460
gene id: 1071381:TPHA_0E00460
uniprot id: G8BTB4
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

1071381:TPHA 0L00740
gene id: 1071381:TPHA_0L00740
uniprot id: G8BZV2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

1071381:TPHA 0L00960
gene id: 1071381:TPHA_0L00960
uniprot id: G8BZX5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0B03080
gene id: 1071381:TPHA_0B03080
uniprot id: G8BPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0C03100
gene id: 1071381:TPHA_0C03100
uniprot id: G8BRT7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D02560
gene id: 1071381:TPHA_0D02560
uniprot id: G8BSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1071381:TPHA 0E00770
gene id: 1071381:TPHA_0E00770
uniprot id: G8BTE4
names: Similarity
messages: Belongs to the WD repeat rae1 family.

1071381:TPHA 0F01540
gene id: 1071381:TPHA_0F01540
uniprot id: G8BV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071381:TPHA 0C04650
gene id: 1071381:TPHA_0C04650
uniprot id: G8BQV3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

1071381:TPHA 0E02200
gene id: 1071381:TPHA_0E02200
uniprot id: G8BTT4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0I02690
gene id: 1071381:TPHA_0I02690
uniprot id: G8BXZ2
names: Similarity
messages: Belongs to the SDHAF4 family.

1071381:TPHA 0N01110
gene id: 1071381:TPHA_0N01110
uniprot id: G8C164
names: Similarity
messages: Belongs to the ERT1/acuK family.

1071381:TPHA 0B04840
gene id: 1071381:TPHA_0B04840
uniprot id: G8BQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

1071381:TPHA 0B00250
gene id: 1071381:TPHA_0B00250
uniprot id: G8BQA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

1071381:TPHA 0C04310
gene id: 1071381:TPHA_0C04310
uniprot id: G8BQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

1071381:TPHA 0H00730
gene id: 1071381:TPHA_0H00730
uniprot id: G8BWX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1071381:TPHA 0G01840
gene id: 1071381:TPHA_0G01840
uniprot id: G8BVU2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

1071381:TPHA 0I00350
gene id: 1071381:TPHA_0I00350
uniprot id: G8BXB4
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1071381:TPHA 0A02880
gene id: 1071381:TPHA_0A02880
uniprot id: G8BN91
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1071381:TPHA 0N00990
gene id: 1071381:TPHA_0N00990
uniprot id: G8C152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

1071381:TPHA 0A02100
gene id: 1071381:TPHA_0A02100
uniprot id: G8BN14
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0F00960
gene id: 1071381:TPHA_0F00960
uniprot id: G8BV00
names: Subcellular Location Annotation
messages: nuclear pore complex

1071381:TPHA 0F01930
gene id: 1071381:TPHA_0F01930
uniprot id: G8BV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071381:TPHA 0M00790
gene id: 1071381:TPHA_0M00790
uniprot id: G8C0D9
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

1071381:TPHA 0A05670
gene id: 1071381:TPHA_0A05670
uniprot id: G8BP13
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0D02010
gene id: 1071381:TPHA_0D02010
uniprot id: G8BSL8
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

1071381:TPHA 0H02610
gene id: 1071381:TPHA_0H02610
uniprot id: G8BWL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

1071381:TPHA 0I00430
gene id: 1071381:TPHA_0I00430
uniprot id: G8BXC2
names: Similarity
messages: Belongs to the PPase family.

1071381:TPHA 0I01740
gene id: 1071381:TPHA_0I01740
uniprot id: G8BXQ0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1071381:TPHA 0J02510
gene id: 1071381:TPHA_0J02510
uniprot id: G8BYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

1071381:TPHA 0I02850
gene id: 1071381:TPHA_0I02850
uniprot id: G8BY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0B03100
gene id: 1071381:TPHA_0B03100
uniprot id: G8BPQ1
names: Similarity
messages: Belongs to the AIM23 family.

1071381:TPHA 0J02770
gene id: 1071381:TPHA_0J02770
uniprot id: G8BZ06
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1071381:TPHA 0B01200
gene id: 1071381:TPHA_0B01200
uniprot id: G8BP61
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

1071381:TPHA 0D01810
gene id: 1071381:TPHA_0D01810
uniprot id: G8BSJ9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

1071381:TPHA 0N00770
gene id: 1071381:TPHA_0N00770
uniprot id: G8C130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0E00500
gene id: 1071381:TPHA_0E00500
uniprot id: G8BTB8
names: Similarity
messages: Belongs to the peptidase C12 family.

1071381:TPHA 0J00230
gene id: 1071381:TPHA_0J00230
uniprot id: G8BYA5
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

1071381:TPHA 0N00970
gene id: 1071381:TPHA_0N00970
uniprot id: G8C150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

1071381:TPHA 0O00240
gene id: 1071381:TPHA_0O00240
uniprot id: G8C1G8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071381:TPHA 0B00540
gene id: 1071381:TPHA_0B00540
uniprot id: G8BQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

1071381:TPHA 0N01020
gene id: 1071381:TPHA_0N01020
uniprot id: G8C155
names: Similarity
messages: Belongs to the LTV1 family.

1071381:TPHA 0J00660
gene id: 1071381:TPHA_0J00660
uniprot id: G8BYE7
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1071381:TPHA 0E02930
gene id: 1071381:TPHA_0E02930
uniprot id: G8BU05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

1071381:TPHA 0J01700
gene id: 1071381:TPHA_0J01700
uniprot id: G8BYP9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0J01920
gene id: 1071381:TPHA_0J01920
uniprot id: G8BYS1
names: Function
names: Similarity
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

1071381:TPHA 0H01570
gene id: 1071381:TPHA_0H01570
uniprot id: G8BX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0B03120
gene id: 1071381:TPHA_0B03120
uniprot id: G8BPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

1071381:TPHA 0M01090
gene id: 1071381:TPHA_0M01090
uniprot id: G8C0G9
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0L00750
gene id: 1071381:TPHA_0L00750
uniprot id: G8BZV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1071381:TPHA 0M01950
gene id: 1071381:TPHA_0M01950
uniprot id: G8C0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

1071381:TPHA 0J02760
gene id: 1071381:TPHA_0J02760
uniprot id: G8BZ05
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

1071381:TPHA 0I01160
gene id: 1071381:TPHA_0I01160
uniprot id: G8BXJ4
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

1071381:TPHA 0N01280
gene id: 1071381:TPHA_0N01280
uniprot id: G8C181
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

1071381:TPHA 0C02890
gene id: 1071381:TPHA_0C02890
uniprot id: G8BRR6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1071381:TPHA 0J01120
gene id: 1071381:TPHA_0J01120
uniprot id: G8BYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

1071381:TPHA 0F01950
gene id: 1071381:TPHA_0F01950
uniprot id: G8BV95
names: Similarity
messages: Belongs to the CAP family.

1071381:TPHA 0F02360
gene id: 1071381:TPHA_0F02360
uniprot id: G8BUD1
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

1071381:TPHA 0E02630
gene id: 1071381:TPHA_0E02630
uniprot id: G8BTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071381:TPHA 0G00700
gene id: 1071381:TPHA_0G00700
uniprot id: G8BVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

1071381:TPHA 0O00150
gene id: 1071381:TPHA_0O00150
uniprot id: G8C1F9
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0E01610
gene id: 1071381:TPHA_0E01610
uniprot id: G8BTM6
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

1071381:TPHA 0E03450
gene id: 1071381:TPHA_0E03450
uniprot id: G8BU57
names: Subcellular Location Annotation
messages: Mitochondrion

1071381:TPHA 0G03000
gene id: 1071381:TPHA_0G03000
uniprot id: G8BW63
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1071381:TPHA 0A00320
gene id: 1071381:TPHA_0A00320
uniprot id: G8BMI9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N00750
gene id: 1071381:TPHA_0N00750
uniprot id: G8C128
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0L01180
gene id: 1071381:TPHA_0L01180
uniprot id: G8BZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071381:TPHA 0C01250
gene id: 1071381:TPHA_0C01250
uniprot id: G8BRA5
names: Similarity
messages: Belongs to the complex I LYR family.

1071381:TPHA 0I00230
gene id: 1071381:TPHA_0I00230
uniprot id: G8BXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

1071381:TPHA 0G00790
gene id: 1071381:TPHA_0G00790
uniprot id: G8BQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0O01630
gene id: 1071381:TPHA_0O01630
uniprot id: G8C1V2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071381:TPHA 0I01140
gene id: 1071381:TPHA_0I01140
uniprot id: G8BXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

1071381:TPHA 0C01010
gene id: 1071381:TPHA_0C01010
uniprot id: G8BR81
names: Similarity
messages: Belongs to the LCL2 family.

1071381:TPHA 0F03420
gene id: 1071381:TPHA_0F03420
uniprot id: G8BUN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

1071381:TPHA 0A01080
gene id: 1071381:TPHA_0A01080
uniprot id: G8BMR5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1071381:TPHA 0A02750
gene id: 1071381:TPHA_0A02750
uniprot id: G8BN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

1071381:TPHA 0B01810
gene id: 1071381:TPHA_0B01810
uniprot id: G8BPC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0C02310
gene id: 1071381:TPHA_0C02310
uniprot id: G8BRK8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

1071381:TPHA 0P01070
gene id: 1071381:TPHA_0P01070
uniprot id: G8C287
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

1071381:TPHA 0L01060
gene id: 1071381:TPHA_0L01060
uniprot id: G8BZY5
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0G00410
gene id: 1071381:TPHA_0G00410
uniprot id: G8BVE9
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

1071381:TPHA 0M00540
gene id: 1071381:TPHA_0M00540
uniprot id: G8C0B4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D01260
gene id: 1071381:TPHA_0D01260
uniprot id: G8BSE6
names: Similarity
messages: Belongs to the peptidase A1 family.

1071381:TPHA 0I02230
gene id: 1071381:TPHA_0I02230
uniprot id: G8BXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

1071381:TPHA 0I00310
gene id: 1071381:TPHA_0I00310
uniprot id: G8BXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

1071381:TPHA 0K01170
gene id: 1071381:TPHA_0K01170
uniprot id: G8BZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

1071381:TPHA 0C03750
gene id: 1071381:TPHA_0C03750
uniprot id: G8BQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071381:TPHA 0J03080
gene id: 1071381:TPHA_0J03080
uniprot id: G8BY77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

1071381:TPHA 0B01090
gene id: 1071381:TPHA_0B01090
uniprot id: G8BQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0F01510
gene id: 1071381:TPHA_0F01510
uniprot id: G8BV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0A00770
gene id: 1071381:TPHA_0A00770
uniprot id: G8BMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071381:TPHA 0I00120
gene id: 1071381:TPHA_0I00120
uniprot id: G8BX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

1071381:TPHA 0H02550
gene id: 1071381:TPHA_0H02550
uniprot id: G8BWK7
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

1071381:TPHA 0F03300
gene id: 1071381:TPHA_0F03300
uniprot id: G8BUM5
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

1071381:TPHA 0O01010
gene id: 1071381:TPHA_0O01010
uniprot id: G8C1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071381:TPHA 0A03930
gene id: 1071381:TPHA_0A03930
uniprot id: G8BNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

1071381:TPHA 0J03110
gene id: 1071381:TPHA_0J03110
uniprot id: G8BY80
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

1071381:TPHA 0A05910
gene id: 1071381:TPHA_0A05910
uniprot id: G8BP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

1071381:TPHA 0G02790
gene id: 1071381:TPHA_0G02790
uniprot id: G8BW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

1071381:TPHA 0N01090
gene id: 1071381:TPHA_0N01090
uniprot id: G8C162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0C03060
gene id: 1071381:TPHA_0C03060
uniprot id: G8BRT3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A03920
gene id: 1071381:TPHA_0A03920
uniprot id: G8BNJ0
names: Similarity
messages: Belongs to the peptidase M28 family.

1071381:TPHA 0G02440
gene id: 1071381:TPHA_0G02440
uniprot id: G8BW01
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1071381:TPHA 0N01000
gene id: 1071381:TPHA_0N01000
uniprot id: G8C153
names: Similarity
messages: Belongs to the NOP9 family.

1071381:TPHA 0N00180
gene id: 1071381:TPHA_0N00180
uniprot id: G8C0X1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071381:TPHA 0N00220
gene id: 1071381:TPHA_0N00220
uniprot id: G8C0X5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071381:TPHA 0J02680
gene id: 1071381:TPHA_0J02680
uniprot id: G8BYZ6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071381:TPHA 0I00860
gene id: 1071381:TPHA_0I00860
uniprot id: G8BXG4
names: Similarity
messages: Belongs to the ERT1/acuK family.

1071381:TPHA 0B04420
gene id: 1071381:TPHA_0B04420
uniprot id: G8BQ30
names: Similarity
messages: Belongs to the UFD1 family.

1071381:TPHA 0M01210
gene id: 1071381:TPHA_0M01210
uniprot id: G8C0I1
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

1071381:TPHA 0J00390
gene id: 1071381:TPHA_0J00390
uniprot id: G8BYC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071381:TPHA 0E02550
gene id: 1071381:TPHA_0E02550
uniprot id: G8BTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071381:TPHA 0B04600
gene id: 1071381:TPHA_0B04600
uniprot id: G8BQ48
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

1071381:TPHA 0C00720
gene id: 1071381:TPHA_0C00720
uniprot id: G8BR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

1071381:TPHA 0O01370
gene id: 1071381:TPHA_0O01370
uniprot id: G8C1S7
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

1071381:TPHA 0J02190
gene id: 1071381:TPHA_0J02190
uniprot id: G8BYU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

1071381:TPHA 0C04470
gene id: 1071381:TPHA_0C04470
uniprot id: G8BQT6
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

1071381:TPHA 0A00240
gene id: 1071381:TPHA_0A00240
uniprot id: G8BMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0G02820
gene id: 1071381:TPHA_0G02820
uniprot id: G8BW42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0O00210
gene id: 1071381:TPHA_0O00210
uniprot id: G8C1G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

1071381:TPHA 0E02110
gene id: 1071381:TPHA_0E02110
uniprot id: G8BTS5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1071381:TPHA 0H00180
gene id: 1071381:TPHA_0H00180
uniprot id: G8BWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

1071381:TPHA 0A04720
gene id: 1071381:TPHA_0A04720
uniprot id: G8BNR9
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

1071381:TPHA 0J02560
gene id: 1071381:TPHA_0J02560
uniprot id: G8BYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

1071381:TPHA 0L01420
gene id: 1071381:TPHA_0L01420
uniprot id: G8C019
names: Similarity
messages: Belongs to the TTC4 family.

1071381:TPHA 0M00740
gene id: 1071381:TPHA_0M00740
uniprot id: G8C0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

1071381:TPHA 0C00760
gene id: 1071381:TPHA_0C00760
uniprot id: G8BR56
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1071381:TPHA 0M01330
gene id: 1071381:TPHA_0M01330
uniprot id: G8C0J3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

1071381:TPHA 0A02800
gene id: 1071381:TPHA_0A02800
uniprot id: G8BN83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

1071381:TPHA 0D01380
gene id: 1071381:TPHA_0D01380
uniprot id: G8BSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

1071381:TPHA 0K00250
gene id: 1071381:TPHA_0K00250
uniprot id: G8BZ31
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

1071381:TPHA 0A04910
gene id: 1071381:TPHA_0A04910
uniprot id: G8BNT8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1071381:TPHA 0G03330
gene id: 1071381:TPHA_0G03330
uniprot id: G8BW95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

1071381:TPHA 0B01500
gene id: 1071381:TPHA_0B01500
uniprot id: G8BP92
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

1071381:TPHA 0F00130
gene id: 1071381:TPHA_0F00130
uniprot id: G8BUR8
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0I00240
gene id: 1071381:TPHA_0I00240
uniprot id: G8BXA3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

1071381:TPHA 0E00950
gene id: 1071381:TPHA_0E00950
uniprot id: G8BTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

1071381:TPHA 0J00980
gene id: 1071381:TPHA_0J00980
uniprot id: G8BYH8
names: Similarity
messages: Belongs to the SEC6 family.

1071381:TPHA 0H00320
gene id: 1071381:TPHA_0H00320
uniprot id: G8BWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1071381:TPHA 0I01130
gene id: 1071381:TPHA_0I01130
uniprot id: G8BXJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

1071381:TPHA 0L00940
gene id: 1071381:TPHA_0L00940
uniprot id: G8BZX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1071381:TPHA 0E01050
gene id: 1071381:TPHA_0E01050
uniprot id: G8BTH1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0J00750
gene id: 1071381:TPHA_0J00750
uniprot id: G8BYF6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

1071381:TPHA 0A03330
gene id: 1071381:TPHA_0A03330
uniprot id: G8BND2
names: Similarity
messages: Belongs to the PHF5 family.

1071381:TPHA 0E00660
gene id: 1071381:TPHA_0E00660
uniprot id: G8BTD3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071381:TPHA 0E00800
gene id: 1071381:TPHA_0E00800
uniprot id: G8BTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

1071381:TPHA 0D04430
gene id: 1071381:TPHA_0D04430
uniprot id: G8BS02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

1071381:TPHA 0A04340
gene id: 1071381:TPHA_0A04340
uniprot id: G8BNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

1071381:TPHA 0A02600
gene id: 1071381:TPHA_0A02600
uniprot id: G8BN64
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1071381:TPHA 0P00820
gene id: 1071381:TPHA_0P00820
uniprot id: G8C262
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0H03060
gene id: 1071381:TPHA_0H03060
uniprot id: G8BWQ8
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

1071381:TPHA 0N01070
gene id: 1071381:TPHA_0N01070
uniprot id: G8C160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

1071381:TPHA 0L02230
gene id: 1071381:TPHA_0L02230
uniprot id: G8C096
names: Similarity
messages: Belongs to the EFG1 family.

1071381:TPHA 0D02870
gene id: 1071381:TPHA_0D02870
uniprot id: G8BSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

1071381:TPHA 0I00600
gene id: 1071381:TPHA_0I00600
uniprot id: G8BXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

1071381:TPHA 0I01520
gene id: 1071381:TPHA_0I01520
uniprot id: G8BXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071381:TPHA 0B02980
gene id: 1071381:TPHA_0B02980
uniprot id: G8BPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0O00300
gene id: 1071381:TPHA_0O00300
uniprot id: G8C1H4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H02800
gene id: 1071381:TPHA_0H02800
uniprot id: G8BWN2
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071381:TPHA 0B01060
gene id: 1071381:TPHA_0B01060
uniprot id: G8BQI1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C02630
gene id: 1071381:TPHA_0C02630
uniprot id: G8BRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0F03070
gene id: 1071381:TPHA_0F03070
uniprot id: G8BUK2
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

1071381:TPHA 0B02590
gene id: 1071381:TPHA_0B02590
uniprot id: G8BPK1
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

1071381:TPHA 0D00760
gene id: 1071381:TPHA_0D00760
uniprot id: G8BS98
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071381:TPHA 0I02830
gene id: 1071381:TPHA_0I02830
uniprot id: G8BY06
names: Similarity
messages: Belongs to the phospholipid scramblase family.

1071381:TPHA 0E00850
gene id: 1071381:TPHA_0E00850
uniprot id: G8BTF2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

1071381:TPHA 0C04180
gene id: 1071381:TPHA_0C04180
uniprot id: G8BQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E02230
gene id: 1071381:TPHA_0E02230
uniprot id: G8BTT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

1071381:TPHA 0K00420
gene id: 1071381:TPHA_0K00420
uniprot id: G8BZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

1071381:TPHA 0G01310
gene id: 1071381:TPHA_0G01310
uniprot id: G8BVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

1071381:TPHA 0I02460
gene id: 1071381:TPHA_0I02460
uniprot id: G8BXX1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0H01190
gene id: 1071381:TPHA_0H01190
uniprot id: G8BX23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0I03030
gene id: 1071381:TPHA_0I03030
uniprot id: G8BY26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0F02800
gene id: 1071381:TPHA_0F02800
uniprot id: G8BUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B03370
gene id: 1071381:TPHA_0B03370
uniprot id: G8BPS7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

1071381:TPHA 0G01100
gene id: 1071381:TPHA_0G01100
uniprot id: G8BVL9
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

1071381:TPHA 0H01560
gene id: 1071381:TPHA_0H01560
uniprot id: G8BX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1071381:TPHA 0C00270
gene id: 1071381:TPHA_0C00270
uniprot id: G8BR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

1071381:TPHA 0B03020
gene id: 1071381:TPHA_0B03020
uniprot id: G8BPP3
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0G03690
gene id: 1071381:TPHA_0G03690
uniprot id: G8BWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

1071381:TPHA 0F00190
gene id: 1071381:TPHA_0F00190
uniprot id: G8BUS4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A01930
gene id: 1071381:TPHA_0A01930
uniprot id: G8BMZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

1071381:TPHA 0J01280
gene id: 1071381:TPHA_0J01280
uniprot id: G8BYK8
names: Similarity
messages: Belongs to the ETT1 family.

1071381:TPHA 0E02850
gene id: 1071381:TPHA_0E02850
uniprot id: G8BTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

1071381:TPHA 0J01070
gene id: 1071381:TPHA_0J01070
uniprot id: G8BYI7
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0C00330
gene id: 1071381:TPHA_0C00330
uniprot id: G8BR14
names: Similarity
messages: Belongs to the syntaxin family.

1071381:TPHA 0E01640
gene id: 1071381:TPHA_0E01640
uniprot id: G8BTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

1071381:TPHA 0L00290
gene id: 1071381:TPHA_0L00290
uniprot id: G8BZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E00820
gene id: 1071381:TPHA_0E00820
uniprot id: G8BTE9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0C01560
gene id: 1071381:TPHA_0C01560
uniprot id: G8BRD6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E00530
gene id: 1071381:TPHA_0E00530
uniprot id: G8BTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

1071381:TPHA 0C01920
gene id: 1071381:TPHA_0C01920
uniprot id: G8BRH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

1071381:TPHA 0F00590
gene id: 1071381:TPHA_0F00590
uniprot id: G8BUW4
names: Similarity
messages: Belongs to the Fmt family.

1071381:TPHA 0I02500
gene id: 1071381:TPHA_0I02500
uniprot id: G8BXX5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

1071381:TPHA 0B01580
gene id: 1071381:TPHA_0B01580
uniprot id: G8BP99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

1071381:TPHA 0J02920
gene id: 1071381:TPHA_0J02920
uniprot id: G8BY62
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

1071381:TPHA 0B00460
gene id: 1071381:TPHA_0B00460
uniprot id: G8BQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071381:TPHA 0J01050
gene id: 1071381:TPHA_0J01050
uniprot id: G8BYI5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1071381:TPHA 0G00750
gene id: 1071381:TPHA_0G00750
uniprot id: G8BVI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

1071381:TPHA 0B01400
gene id: 1071381:TPHA_0B01400
uniprot id: G8BP82
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1071381:TPHA 0L00590
gene id: 1071381:TPHA_0L00590
uniprot id: G8BZT7
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

1071381:TPHA 0A06060
gene id: 1071381:TPHA_0A06060
uniprot id: G8BP51
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

1071381:TPHA 0F02350
gene id: 1071381:TPHA_0F02350
uniprot id: G8BUD0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

1071381:TPHA 0P00650
gene id: 1071381:TPHA_0P00650
uniprot id: G8C245
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071381:TPHA 0A03070
gene id: 1071381:TPHA_0A03070
uniprot id: G8BNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1071381:TPHA 0D02580
gene id: 1071381:TPHA_0D02580
uniprot id: G8BSS4
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

1071381:TPHA 0H00910
gene id: 1071381:TPHA_0H00910
uniprot id: G8BWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTT106 family.
messages: Chromosome
messages: Nucleus

1071381:TPHA 0I02430
gene id: 1071381:TPHA_0I02430
uniprot id: G8BXW8
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

1071381:TPHA 0E01480
gene id: 1071381:TPHA_0E01480
uniprot id: G8BTL4
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1071381:TPHA 0A05120
gene id: 1071381:TPHA_0A05120
uniprot id: G8BNV9
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0O02010
gene id: 1071381:TPHA_0O02010
uniprot id: G8C1Y9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0O01470
gene id: 1071381:TPHA_0O01470
uniprot id: G8C1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

1071381:TPHA 0K00840
gene id: 1071381:TPHA_0K00840
uniprot id: G8BZ90
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1071381:TPHA 0N01550
gene id: 1071381:TPHA_0N01550
uniprot id: G8C1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

1071381:TPHA 0D02730
gene id: 1071381:TPHA_0D02730
uniprot id: G8BST8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071381:TPHA 0B03450
gene id: 1071381:TPHA_0B03450
uniprot id: G8BPT4
names: Similarity
messages: Belongs to the XPC family.

1071381:TPHA 0H02420
gene id: 1071381:TPHA_0H02420
uniprot id: G8BWJ4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0P00270
gene id: 1071381:TPHA_0P00270
uniprot id: G8C207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

1071381:TPHA 0M01600
gene id: 1071381:TPHA_0M01600
uniprot id: G8C0M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

1071381:TPHA 0G02090
gene id: 1071381:TPHA_0G02090
uniprot id: G8BVW7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1071381:TPHA 0D01490
gene id: 1071381:TPHA_0D01490
uniprot id: G8BSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

1071381:TPHA 0G00960
gene id: 1071381:TPHA_0G00960
uniprot id: G8BVK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0B02310
gene id: 1071381:TPHA_0B02310
uniprot id: G8BPH2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0D01340
gene id: 1071381:TPHA_0D01340
uniprot id: G8BSF4
names: Similarity
messages: Belongs to the APC5 family.

1071381:TPHA 0K01630
gene id: 1071381:TPHA_0K01630
uniprot id: G8BZG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

1071381:TPHA 0D04180
gene id: 1071381:TPHA_0D04180
uniprot id: G8BRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0D04520
gene id: 1071381:TPHA_0D04520
uniprot id: G8BS11
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0D04330
gene id: 1071381:TPHA_0D04330
uniprot id: G8BRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

1071381:TPHA 0J01790
gene id: 1071381:TPHA_0J01790
uniprot id: G8BYQ8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1071381:TPHA 0G01240
gene id: 1071381:TPHA_0G01240
uniprot id: G8BVN3
names: Similarity
messages: Belongs to the MBF1 family.

1071381:TPHA 0A01770
gene id: 1071381:TPHA_0A01770
uniprot id: G8BMY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1071381:TPHA 0C01000
gene id: 1071381:TPHA_0C01000
uniprot id: G8BR80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0C02770
gene id: 1071381:TPHA_0C02770
uniprot id: G8BRQ4
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0G00950
gene id: 1071381:TPHA_0G00950
uniprot id: G8BVK3
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

1071381:TPHA 0C00520
gene id: 1071381:TPHA_0C00520
uniprot id: G8BR33
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E00480
gene id: 1071381:TPHA_0E00480
uniprot id: G8BTB6
names: Similarity
messages: Belongs to the VPS25 family.

1071381:TPHA 0C02870
gene id: 1071381:TPHA_0C02870
uniprot id: G8BRR4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1071381:TPHA 0D04460
gene id: 1071381:TPHA_0D04460
uniprot id: G8BS05
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

1071381:TPHA 0D02290
gene id: 1071381:TPHA_0D02290
uniprot id: G8BSP6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

1071381:TPHA 0C01130
gene id: 1071381:TPHA_0C01130
uniprot id: G8BR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

1071381:TPHA 0F00550
gene id: 1071381:TPHA_0F00550
uniprot id: G8BUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

1071381:TPHA 0A05830
gene id: 1071381:TPHA_0A05830
uniprot id: G8BP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

1071381:TPHA 0L00620
gene id: 1071381:TPHA_0L00620
uniprot id: G8BZU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

1071381:TPHA 0D02790
gene id: 1071381:TPHA_0D02790
uniprot id: G8BSU4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

1071381:TPHA 0E01740
gene id: 1071381:TPHA_0E01740
uniprot id: G8BTN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

1071381:TPHA 0L02360
gene id: 1071381:TPHA_0L02360
uniprot id: G8C0A9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1071381:TPHA 0L01690
gene id: 1071381:TPHA_0L01690
uniprot id: G8C044
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

1071381:TPHA 0C02830
gene id: 1071381:TPHA_0C02830
uniprot id: G8BRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E03080
gene id: 1071381:TPHA_0E03080
uniprot id: G8BU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

1071381:TPHA 0B01940
gene id: 1071381:TPHA_0B01940
uniprot id: G8BPD5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F00540
gene id: 1071381:TPHA_0F00540
uniprot id: G8BUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

1071381:TPHA 0C03030
gene id: 1071381:TPHA_0C03030
uniprot id: G8BRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0K00680
gene id: 1071381:TPHA_0K00680
uniprot id: G8BZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Membrane
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

1071381:TPHA 0H01210
gene id: 1071381:TPHA_0H01210
uniprot id: G8BX25
names: Similarity
messages: Belongs to the enolase family.

1071381:TPHA 0O01610
gene id: 1071381:TPHA_0O01610
uniprot id: G8C1V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

1071381:TPHA 0J01940
gene id: 1071381:TPHA_0J01940
uniprot id: G8BYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

1071381:TPHA 0I02010
gene id: 1071381:TPHA_0I02010
uniprot id: G8BXS7
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0F03100
gene id: 1071381:TPHA_0F03100
uniprot id: G8BUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

1071381:TPHA 0E02790
gene id: 1071381:TPHA_0E02790
uniprot id: G8BTZ1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071381:TPHA 0D01330
gene id: 1071381:TPHA_0D01330
uniprot id: G8BSF3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071381:TPHA 0D00360
gene id: 1071381:TPHA_0D00360
uniprot id: G8BS59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0E03595
gene id: 1071381:TPHA_0E03595
uniprot id: G8BUB5
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0L02290
gene id: 1071381:TPHA_0L02290
uniprot id: G8C0A2
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0N01400
gene id: 1071381:TPHA_0N01400
uniprot id: G8C193
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J00310
gene id: 1071381:TPHA_0J00310
uniprot id: G8BYB2
names: Similarity
messages: Belongs to the NPR2 family.

1071381:TPHA 0P01360
gene id: 1071381:TPHA_0P01360
uniprot id: G8C2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1071381:TPHA 0I01630
gene id: 1071381:TPHA_0I01630
uniprot id: G8BXN9
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1071381:TPHA 0L01510
gene id: 1071381:TPHA_0L01510
uniprot id: G8C028
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

1071381:TPHA 0E02780
gene id: 1071381:TPHA_0E02780
uniprot id: G8BTZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

1071381:TPHA 0A00680
gene id: 1071381:TPHA_0A00680
uniprot id: G8BMM5
names: Similarity
messages: Belongs to the VPS72/YL1 family.

1071381:TPHA 0L01140
gene id: 1071381:TPHA_0L01140
uniprot id: G8BZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

1071381:TPHA 0C03720
gene id: 1071381:TPHA_0C03720
uniprot id: G8BQL2
names: Similarity
messages: Belongs to the ATG16 family.

1071381:TPHA 0I02730
gene id: 1071381:TPHA_0I02730
uniprot id: G8BXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

1071381:TPHA 0B00910
gene id: 1071381:TPHA_0B00910
uniprot id: G8BQG6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1071381:TPHA 0C04830
gene id: 1071381:TPHA_0C04830
uniprot id: G8BQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0F00750
gene id: 1071381:TPHA_0F00750
uniprot id: G8BUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0C03500
gene id: 1071381:TPHA_0C03500
uniprot id: G8BQJ0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O01650
gene id: 1071381:TPHA_0O01650
uniprot id: G8C1V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0D03010
gene id: 1071381:TPHA_0D03010
uniprot id: G8BSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

1071381:TPHA 0G00560
gene id: 1071381:TPHA_0G00560
uniprot id: G8BVG4
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0D02910
gene id: 1071381:TPHA_0D02910
uniprot id: G8BSV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1071381:TPHA 0J02910
gene id: 1071381:TPHA_0J02910
uniprot id: G8BY61
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071381:TPHA 0B01840
gene id: 1071381:TPHA_0B01840
uniprot id: G8BPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0H01650
gene id: 1071381:TPHA_0H01650
uniprot id: G8BX67
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00280
gene id: 1071381:TPHA_0L00280
uniprot id: G8BZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0A05810
gene id: 1071381:TPHA_0A05810
uniprot id: G8BP27
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

1071381:TPHA 0D02470
gene id: 1071381:TPHA_0D02470
uniprot id: G8BSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

1071381:TPHA 0D03000
gene id: 1071381:TPHA_0D03000
uniprot id: G8BSW5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E02450
gene id: 1071381:TPHA_0E02450
uniprot id: G8BTV9
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071381:TPHA 0H01690
gene id: 1071381:TPHA_0H01690
uniprot id: G8BX71
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

1071381:TPHA 0C00590
gene id: 1071381:TPHA_0C00590
uniprot id: G8BR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

1071381:TPHA 0H01760
gene id: 1071381:TPHA_0H01760
uniprot id: G8BX78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

1071381:TPHA 0I01500
gene id: 1071381:TPHA_0I01500
uniprot id: G8BXM8
names: Similarity
messages: Belongs to the peptidase S1C family.

1071381:TPHA 0B01070
gene id: 1071381:TPHA_0B01070
uniprot id: G8BQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3.
messages: Nucleus

1071381:TPHA 0I00210
gene id: 1071381:TPHA_0I00210
uniprot id: G8BXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0G00400
gene id: 1071381:TPHA_0G00400
uniprot id: G8BVE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1071381:TPHA 0O00760
gene id: 1071381:TPHA_0O00760
uniprot id: G8C1L7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

1071381:TPHA 0J01060
gene id: 1071381:TPHA_0J01060
uniprot id: G8BYI6
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

1071381:TPHA 0F00480
gene id: 1071381:TPHA_0F00480
uniprot id: G8BUV3
names: Similarity
messages: Belongs to the PITHD1 family.

1071381:TPHA 0P00540
gene id: 1071381:TPHA_0P00540
uniprot id: G8C234
names: Similarity
messages: Belongs to the UPF0045 family.

1071381:TPHA 0L01750
gene id: 1071381:TPHA_0L01750
uniprot id: G8C050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0H02340
gene id: 1071381:TPHA_0H02340
uniprot id: G8BWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1071381:TPHA 0E02400
gene id: 1071381:TPHA_0E02400
uniprot id: G8BTV4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1071381:TPHA 0A04930
gene id: 1071381:TPHA_0A04930
uniprot id: G8BNU0
names: Similarity
messages: Belongs to the ZPR1 family.

1071381:TPHA 0O00400
gene id: 1071381:TPHA_0O00400
uniprot id: G8C1I3
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

1071381:TPHA 0C02840
gene id: 1071381:TPHA_0C02840
uniprot id: G8BRR1
names: Similarity
messages: Belongs to the Rab GDI family.

1071381:TPHA 0C01930
gene id: 1071381:TPHA_0C01930
uniprot id: G8BRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

1071381:TPHA 0B04260
gene id: 1071381:TPHA_0B04260
uniprot id: G8BQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

1071381:TPHA 0F01860
gene id: 1071381:TPHA_0F01860
uniprot id: G8BV86
names: Similarity
messages: Belongs to the malate synthase family.

1071381:TPHA 0M00210
gene id: 1071381:TPHA_0M00210
uniprot id: G8C0T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

1071381:TPHA 0H00380
gene id: 1071381:TPHA_0H00380
uniprot id: G8BWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0G03270
gene id: 1071381:TPHA_0G03270
uniprot id: G8BW89
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1071381:TPHA 0O00610
gene id: 1071381:TPHA_0O00610
uniprot id: G8C1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

1071381:TPHA 0O01830
gene id: 1071381:TPHA_0O01830
uniprot id: G8C1X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

1071381:TPHA 0H01920
gene id: 1071381:TPHA_0H01920
uniprot id: G8BWE6
names: Similarity
messages: Belongs to the Tango6 family.

1071381:TPHA 0P01790
gene id: 1071381:TPHA_0P01790
uniprot id: G8C2F8
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

1071381:TPHA 0H02140
gene id: 1071381:TPHA_0H02140
uniprot id: G8BWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0B03660
gene id: 1071381:TPHA_0B03660
uniprot id: G8BPV7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1071381:TPHA 0K02310
gene id: 1071381:TPHA_0K02310
uniprot id: G8BZN3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L01530
gene id: 1071381:TPHA_0L01530
uniprot id: G8C030
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0A03400
gene id: 1071381:TPHA_0A03400
uniprot id: G8BND9
names: Similarity
messages: Belongs to the TFIIB family.

1071381:TPHA 0C04500
gene id: 1071381:TPHA_0C04500
uniprot id: G8BQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1071381:TPHA 0C00540
gene id: 1071381:TPHA_0C00540
uniprot id: G8BR35
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1071381:TPHA 0M00190
gene id: 1071381:TPHA_0M00190
uniprot id: G8C0T6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E02660
gene id: 1071381:TPHA_0E02660
uniprot id: G8BTY0
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1071381:TPHA 0G00280
gene id: 1071381:TPHA_0G00280
uniprot id: G8BVD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0F02260
gene id: 1071381:TPHA_0F02260
uniprot id: G8BUC1
names: Similarity
messages: Belongs to the FAH family.

1071381:TPHA 0P01100
gene id: 1071381:TPHA_0P01100
uniprot id: G8C290
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01220
gene id: 1071381:TPHA_0C01220
uniprot id: G8BRA2
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family.

1071381:TPHA 0C01440
gene id: 1071381:TPHA_0C01440
uniprot id: G8BRC4
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071381:TPHA 0J00300
gene id: 1071381:TPHA_0J00300
uniprot id: G8BYB1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0E02070
gene id: 1071381:TPHA_0E02070
uniprot id: G8BTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

1071381:TPHA 0I01530
gene id: 1071381:TPHA_0I01530
uniprot id: G8BXN1
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

1071381:TPHA 0N01540
gene id: 1071381:TPHA_0N01540
uniprot id: G8C1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0C02370
gene id: 1071381:TPHA_0C02370
uniprot id: G8BRL4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

1071381:TPHA 0I01100
gene id: 1071381:TPHA_0I01100
uniprot id: G8BXI8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0J00760
gene id: 1071381:TPHA_0J00760
uniprot id: G8BYF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
messages: Mitochondrion

1071381:TPHA 0M01290
gene id: 1071381:TPHA_0M01290
uniprot id: G8C0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0A04130
gene id: 1071381:TPHA_0A04130
uniprot id: G8BNL0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

1071381:TPHA 0C00170
gene id: 1071381:TPHA_0C00170
uniprot id: G8BQZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1071381:TPHA 0C03640
gene id: 1071381:TPHA_0C03640
uniprot id: G8BQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

1071381:TPHA 0O00410
gene id: 1071381:TPHA_0O00410
uniprot id: G8C1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071381:TPHA 0A01990
gene id: 1071381:TPHA_0A01990
uniprot id: G8BN03
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F02250
gene id: 1071381:TPHA_0F02250
uniprot id: G8BUC0
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

1071381:TPHA 0F01710
gene id: 1071381:TPHA_0F01710
uniprot id: G8BV73
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1071381:TPHA 0C02240
gene id: 1071381:TPHA_0C02240
uniprot id: G8BRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

1071381:TPHA 0L02000
gene id: 1071381:TPHA_0L02000
uniprot id: G8C074
names: Similarity
messages: Belongs to the sulfiredoxin family.

1071381:TPHA 0B01040
gene id: 1071381:TPHA_0B01040
uniprot id: G8BQH9
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1071381:TPHA 0N01300
gene id: 1071381:TPHA_0N01300
uniprot id: G8C183
names: Similarity
messages: Belongs to the NifU family.

1071381:TPHA 0E01660
gene id: 1071381:TPHA_0E01660
uniprot id: G8BTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0A01410
gene id: 1071381:TPHA_0A01410
uniprot id: G8BMU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

1071381:TPHA 0P00380
gene id: 1071381:TPHA_0P00380
uniprot id: G8C218
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0J00170
gene id: 1071381:TPHA_0J00170
uniprot id: G8BY99
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0G00620
gene id: 1071381:TPHA_0G00620
uniprot id: G8BVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071381:TPHA 0C03140
gene id: 1071381:TPHA_0C03140
uniprot id: G8BRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

1071381:TPHA 0P00700
gene id: 1071381:TPHA_0P00700
uniprot id: G8C250
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1071381:TPHA 0B02325
gene id: 1071381:TPHA_0B02325
uniprot id: G8BPH4
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

1071381:TPHA 0M01410
gene id: 1071381:TPHA_0M01410
uniprot id: G8C0K1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H01100
gene id: 1071381:TPHA_0H01100
uniprot id: G8BX14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0N00300
gene id: 1071381:TPHA_0N00300
uniprot id: G8C0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

1071381:TPHA 0J00600
gene id: 1071381:TPHA_0J00600
uniprot id: G8BYE1
names: Similarity
messages: Belongs to the GET4 family.

1071381:TPHA 0D03610
gene id: 1071381:TPHA_0D03610
uniprot id: G8BT25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1071381:TPHA 0A00330
gene id: 1071381:TPHA_0A00330
uniprot id: G8BMJ0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071381:TPHA 0C04570
gene id: 1071381:TPHA_0C04570
uniprot id: G8BQU5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1071381:TPHA 0P01270
gene id: 1071381:TPHA_0P01270
uniprot id: G8C2A7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

1071381:TPHA 0O01870
gene id: 1071381:TPHA_0O01870
uniprot id: G8C1X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

1071381:TPHA 0O01090
gene id: 1071381:TPHA_0O01090
uniprot id: G8C1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

1071381:TPHA 0M01440
gene id: 1071381:TPHA_0M01440
uniprot id: G8C0K4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1071381:TPHA 0A00820
gene id: 1071381:TPHA_0A00820
uniprot id: G8BMN9
names: Similarity
messages: Belongs to the BRX1 family.

1071381:TPHA 0E03390
gene id: 1071381:TPHA_0E03390
uniprot id: G8BU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0F03390
gene id: 1071381:TPHA_0F03390
uniprot id: G8BUN4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0F02460
gene id: 1071381:TPHA_0F02460
uniprot id: G8BUE1
names: Similarity
messages: Belongs to the lysophospholipase family.

1071381:TPHA 0B03400
gene id: 1071381:TPHA_0B03400
uniprot id: G8BPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071381:TPHA 0A03730
gene id: 1071381:TPHA_0A03730
uniprot id: G8BNH1
names: Similarity
messages: Belongs to the small Tim family.

1071381:TPHA 0B03670
gene id: 1071381:TPHA_0B03670
uniprot id: G8BPV8
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O00310
gene id: 1071381:TPHA_0O00310
uniprot id: G8C1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

1071381:TPHA 0H00450
gene id: 1071381:TPHA_0H00450
uniprot id: G8BWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

1071381:TPHA 0A00460
gene id: 1071381:TPHA_0A00460
uniprot id: G8BMK3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

1071381:TPHA 0K00160
gene id: 1071381:TPHA_0K00160
uniprot id: G8BZ22
names: Similarity
messages: Belongs to the VPS29 family.

1071381:TPHA 0A01760
gene id: 1071381:TPHA_0A01760
uniprot id: G8BMY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0D01370
gene id: 1071381:TPHA_0D01370
uniprot id: G8BSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG29 family.
messages: Preautophagosomal structure

1071381:TPHA 0M00970
gene id: 1071381:TPHA_0M00970
uniprot id: G8C0F6
names: Similarity
messages: Belongs to the VPS54 family.

1071381:TPHA 0H01220
gene id: 1071381:TPHA_0H01220
uniprot id: G8BX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

1071381:TPHA 0C02710
gene id: 1071381:TPHA_0C02710
uniprot id: G8BRP8
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

1071381:TPHA 0E03660
gene id: 1071381:TPHA_0E03660
uniprot id: G8BU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0A02110
gene id: 1071381:TPHA_0A02110
uniprot id: G8BN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

1071381:TPHA 0P00720
gene id: 1071381:TPHA_0P00720
uniprot id: G8C252
names: Similarity
messages: Belongs to the peptidase M24B family.

1071381:TPHA 0A03470
gene id: 1071381:TPHA_0A03470
uniprot id: G8BNE5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1071381:TPHA 0A02070
gene id: 1071381:TPHA_0A02070
uniprot id: G8BN11
names: Similarity
messages: Belongs to the MYG1 family.

1071381:TPHA 0F00670
gene id: 1071381:TPHA_0F00670
uniprot id: G8BUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

1071381:TPHA 0C00380
gene id: 1071381:TPHA_0C00380
uniprot id: G8BR19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

1071381:TPHA 0I01700
gene id: 1071381:TPHA_0I01700
uniprot id: G8BXP6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

1071381:TPHA 0P00600
gene id: 1071381:TPHA_0P00600
uniprot id: G8C240
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1071381:TPHA 0L02190
gene id: 1071381:TPHA_0L02190
uniprot id: G8C092
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1071381:TPHA 0H01170
gene id: 1071381:TPHA_0H01170
uniprot id: G8BX21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0E02260
gene id: 1071381:TPHA_0E02260
uniprot id: G8BTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

1071381:TPHA 0C03920
gene id: 1071381:TPHA_0C03920
uniprot id: G8BQN0
names: Similarity
messages: Belongs to the CWC16 family.

1071381:TPHA 0I00620
gene id: 1071381:TPHA_0I00620
uniprot id: G8BXE0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P01840
gene id: 1071381:TPHA_0P01840
uniprot id: G8C2G3
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1071381:TPHA 0C03160
gene id: 1071381:TPHA_0C03160
uniprot id: G8BRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

1071381:TPHA 0E02890
gene id: 1071381:TPHA_0E02890
uniprot id: G8BU01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPS2 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
messages: Membrane
messages: Nucleus membrane
messages: spindle pole body

1071381:TPHA 0A04710
gene id: 1071381:TPHA_0A04710
uniprot id: G8BNR8
names: Similarity
messages: Belongs to the MEMO1 family.

1071381:TPHA 0A03050
gene id: 1071381:TPHA_0A03050
uniprot id: G8BNA5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1071381:TPHA 0H01710
gene id: 1071381:TPHA_0H01710
uniprot id: G8BX73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

1071381:TPHA 0H02320
gene id: 1071381:TPHA_0H02320
uniprot id: G8BWI5
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

1071381:TPHA 0D02950
gene id: 1071381:TPHA_0D02950
uniprot id: G8BSW0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01460
gene id: 1071381:TPHA_0C01460
uniprot id: G8BRC6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B01300
gene id: 1071381:TPHA_0B01300
uniprot id: G8BP72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0E03140
gene id: 1071381:TPHA_0E03140
uniprot id: G8BU26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0E02340
gene id: 1071381:TPHA_0E02340
uniprot id: G8BTU8
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

1071381:TPHA 0C00710
gene id: 1071381:TPHA_0C00710
uniprot id: G8BR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

1071381:TPHA 0G02420
gene id: 1071381:TPHA_0G02420
uniprot id: G8BVZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071381:TPHA 0L01190
gene id: 1071381:TPHA_0L01190
uniprot id: G8BZZ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071381:TPHA 0H02790
gene id: 1071381:TPHA_0H02790
uniprot id: G8BWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

1071381:TPHA 0B04200
gene id: 1071381:TPHA_0B04200
uniprot id: G8BQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

1071381:TPHA 0N01470
gene id: 1071381:TPHA_0N01470
uniprot id: G8C1A0
names: Similarity
messages: Belongs to the CCS1 family.

1071381:TPHA 0G01230
gene id: 1071381:TPHA_0G01230
uniprot id: G8BVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

1071381:TPHA 0B02170
gene id: 1071381:TPHA_0B02170
uniprot id: G8BPF8
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

1071381:TPHA 0N01290
gene id: 1071381:TPHA_0N01290
uniprot id: G8C182
names: Similarity
messages: Belongs to the APC10 family.

1071381:TPHA 0G02510
gene id: 1071381:TPHA_0G02510
uniprot id: G8BW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0K01470
gene id: 1071381:TPHA_0K01470
uniprot id: G8BZF2
names: Similarity
messages: Belongs to the cullin family.

1071381:TPHA 0P00370
gene id: 1071381:TPHA_0P00370
uniprot id: G8C217
names: Similarity
messages: Belongs to the peptidase C48 family.

1071381:TPHA 0O01330
gene id: 1071381:TPHA_0O01330
uniprot id: G8C1S3
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

1071381:TPHA 0I01230
gene id: 1071381:TPHA_0I01230
uniprot id: G8BXK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Required for assembly of cytochrome c oxidase (complex IV).

1071381:TPHA 0D01220
gene id: 1071381:TPHA_0D01220
uniprot id: G8BSE2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1071381:TPHA 0A05520
gene id: 1071381:TPHA_0A05520
uniprot id: G8BNZ8
names: Similarity
messages: Belongs to the peptidase S10 family.

1071381:TPHA 0A04020
gene id: 1071381:TPHA_0A04020
uniprot id: G8BNK0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0D01780
gene id: 1071381:TPHA_0D01780
uniprot id: G8BSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0J03000
gene id: 1071381:TPHA_0J03000
uniprot id: G8BY69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

1071381:TPHA 0F03350
gene id: 1071381:TPHA_0F03350
uniprot id: G8BUN0
names: Similarity
messages: Belongs to the NAD kinase family.

1071381:TPHA 0A00300
gene id: 1071381:TPHA_0A00300
uniprot id: G8BMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

1071381:TPHA 0C03790
gene id: 1071381:TPHA_0C03790
uniprot id: G8BQL9
names: Subcellular Location Annotation
messages: nuclear pore complex

1071381:TPHA 0K02100
gene id: 1071381:TPHA_0K02100
uniprot id: G8BZL5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0J03100
gene id: 1071381:TPHA_0J03100
uniprot id: G8BY79
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

1071381:TPHA 0C04850
gene id: 1071381:TPHA_0C04850
uniprot id: G8BQX2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

1071381:TPHA 0O01500
gene id: 1071381:TPHA_0O01500
uniprot id: G8C1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0D01970
gene id: 1071381:TPHA_0D01970
uniprot id: G8BSL4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0A00270
gene id: 1071381:TPHA_0A00270
uniprot id: G8BMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

1071381:TPHA 0E03490
gene id: 1071381:TPHA_0E03490
uniprot id: G8BU61
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1071381:TPHA 0C01950
gene id: 1071381:TPHA_0C01950
uniprot id: G8BRH4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0F02980
gene id: 1071381:TPHA_0F02980
uniprot id: G8BUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

1071381:TPHA 0J02570
gene id: 1071381:TPHA_0J02570
uniprot id: G8BYY5
names: Similarity
messages: Belongs to the SELO family.

1071381:TPHA 0F02710
gene id: 1071381:TPHA_0F02710
uniprot id: G8BUG5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

1071381:TPHA 0G01250
gene id: 1071381:TPHA_0G01250
uniprot id: G8BVN4
names: Similarity
messages: Belongs to the RNase H family.

1071381:TPHA 0H00720
gene id: 1071381:TPHA_0H00720
uniprot id: G8BWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1071381:TPHA 0L00830
gene id: 1071381:TPHA_0L00830
uniprot id: G8BZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

1071381:TPHA 0D01160
gene id: 1071381:TPHA_0D01160
uniprot id: G8BSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0K02230
gene id: 1071381:TPHA_0K02230
uniprot id: G8BZM5
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

1071381:TPHA 0D02880
gene id: 1071381:TPHA_0D02880
uniprot id: G8BSV3
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0H00490
gene id: 1071381:TPHA_0H00490
uniprot id: G8BWV5
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0G03400
gene id: 1071381:TPHA_0G03400
uniprot id: G8BWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

1071381:TPHA 0H02430
gene id: 1071381:TPHA_0H02430
uniprot id: G8BWJ5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071381:TPHA 0M01130
gene id: 1071381:TPHA_0M01130
uniprot id: G8C0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

1071381:TPHA 0C04700
gene id: 1071381:TPHA_0C04700
uniprot id: G8BQV8
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0H00130
gene id: 1071381:TPHA_0H00130
uniprot id: G8BWS0
names: Similarity
messages: Belongs to the Rab GDI family.

1071381:TPHA 0C04710
gene id: 1071381:TPHA_0C04710
uniprot id: G8BQV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0F00950
gene id: 1071381:TPHA_0F00950
uniprot id: G8BZD6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1071381:TPHA 0J00570
gene id: 1071381:TPHA_0J00570
uniprot id: G8BYD8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1071381:TPHA 0D02160
gene id: 1071381:TPHA_0D02160
uniprot id: G8BSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

1071381:TPHA 0F00410
gene id: 1071381:TPHA_0F00410
uniprot id: G8BUU6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B03830
gene id: 1071381:TPHA_0B03830
uniprot id: G8BPX4
names: Similarity
messages: Belongs to the WrbA family.

1071381:TPHA 0I01790
gene id: 1071381:TPHA_0I01790
uniprot id: G8BXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

1071381:TPHA 0E01080
gene id: 1071381:TPHA_0E01080
uniprot id: G8BTH4
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

1071381:TPHA 0C03460
gene id: 1071381:TPHA_0C03460
uniprot id: G8BRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0P00120
gene id: 1071381:TPHA_0P00120
uniprot id: G8C1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0A00410
gene id: 1071381:TPHA_0A00410
uniprot id: G8BMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071381:TPHA 0F02990
gene id: 1071381:TPHA_0F02990
uniprot id: G8BUJ4
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071381:TPHA 0D00750
gene id: 1071381:TPHA_0D00750
uniprot id: G8BS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0L01840
gene id: 1071381:TPHA_0L01840
uniprot id: G8C059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

1071381:TPHA 0A02690
gene id: 1071381:TPHA_0A02690
uniprot id: G8BN73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

1071381:TPHA 0C01060
gene id: 1071381:TPHA_0C01060
uniprot id: G8BR86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the dehydroquinate synthase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

1071381:TPHA 0A02370
gene id: 1071381:TPHA_0A02370
uniprot id: G8BN41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

1071381:TPHA 0P00760
gene id: 1071381:TPHA_0P00760
uniprot id: G8C256
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

1071381:TPHA 0M00340
gene id: 1071381:TPHA_0M00340
uniprot id: G8C0U8
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

1071381:TPHA 0K01930
gene id: 1071381:TPHA_0K01930
uniprot id: G8BZJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

1071381:TPHA 0H02540
gene id: 1071381:TPHA_0H02540
uniprot id: G8BWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0K00370
gene id: 1071381:TPHA_0K00370
uniprot id: G8BZ43
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1071381:TPHA 0M02100
gene id: 1071381:TPHA_0M02100
uniprot id: G8C0R9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

1071381:TPHA 0N00540
gene id: 1071381:TPHA_0N00540
uniprot id: G8C106
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

1071381:TPHA 0B01130
gene id: 1071381:TPHA_0B01130
uniprot id: G8BQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

1071381:TPHA 0H02300
gene id: 1071381:TPHA_0H02300
uniprot id: G8BWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

1071381:TPHA 0A01360
gene id: 1071381:TPHA_0A01360
uniprot id: G8BMU1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01240
gene id: 1071381:TPHA_0C01240
uniprot id: G8BRA4
names: Similarity
messages: Belongs to the TPA1 family.

1071381:TPHA 0C04360
gene id: 1071381:TPHA_0C04360
uniprot id: G8BQS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1071381:TPHA 0B02490
gene id: 1071381:TPHA_0B02490
uniprot id: G8BPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0G02190
gene id: 1071381:TPHA_0G02190
uniprot id: G8BVX7
names: Similarity
messages: Belongs to the CCDC25 family.

1071381:TPHA 0A06070
gene id: 1071381:TPHA_0A06070
uniprot id: G8BP52
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071381:TPHA 0F02580
gene id: 1071381:TPHA_0F02580
uniprot id: G8BUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

1071381:TPHA 0N00370
gene id: 1071381:TPHA_0N00370
uniprot id: G8C0Z0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

1071381:TPHA 0D00630
gene id: 1071381:TPHA_0D00630
uniprot id: G8BS86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0B01010
gene id: 1071381:TPHA_0B01010
uniprot id: G8BQH6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

1071381:TPHA 0H03080
gene id: 1071381:TPHA_0H03080
uniprot id: G8BWR0
names: Similarity
messages: Belongs to the calreticulin family.

1071381:TPHA 0D02170
gene id: 1071381:TPHA_0D02170
uniprot id: G8BSN4
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

1071381:TPHA 0E01280
gene id: 1071381:TPHA_0E01280
uniprot id: G8BTJ5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0B00640
gene id: 1071381:TPHA_0B00640
uniprot id: G8BQD9
names: Similarity
messages: Belongs to the Mo25 family.

1071381:TPHA 0A02020
gene id: 1071381:TPHA_0A02020
uniprot id: G8BN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

1071381:TPHA 0C01800
gene id: 1071381:TPHA_0C01800
uniprot id: G8BRG0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1071381:TPHA 0B03700
gene id: 1071381:TPHA_0B03700
uniprot id: G8BPW1
names: Similarity
messages: Belongs to the DCC1 family.

1071381:TPHA 0K00320
gene id: 1071381:TPHA_0K00320
uniprot id: G8BZ38
names: Similarity
messages: Belongs to the guanylate kinase family.

1071381:TPHA 0M00880
gene id: 1071381:TPHA_0M00880
uniprot id: G8C0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071381:TPHA 0A01260
gene id: 1071381:TPHA_0A01260
uniprot id: G8BMT2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0D02600
gene id: 1071381:TPHA_0D02600
uniprot id: G8BSS6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1071381:TPHA 0M01200
gene id: 1071381:TPHA_0M01200
uniprot id: G8C0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0B03950
gene id: 1071381:TPHA_0B03950
uniprot id: G8BPY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0A05340
gene id: 1071381:TPHA_0A05340
uniprot id: G8BNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

1071381:TPHA 0F01290
gene id: 1071381:TPHA_0F01290
uniprot id: G8BV32
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0I00160
gene id: 1071381:TPHA_0I00160
uniprot id: G8BX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

1071381:TPHA 0D04050
gene id: 1071381:TPHA_0D04050
uniprot id: G8BT67
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0A02470
gene id: 1071381:TPHA_0A02470
uniprot id: G8BN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

1071381:TPHA 0K01750
gene id: 1071381:TPHA_0K01750
uniprot id: G8BZI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

1071381:TPHA 0L01150
gene id: 1071381:TPHA_0L01150
uniprot id: G8BZZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

1071381:TPHA 0K02180
gene id: 1071381:TPHA_0K02180
uniprot id: G8BZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0B01670
gene id: 1071381:TPHA_0B01670
uniprot id: G8BPA9
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

1071381:TPHA 0J01230
gene id: 1071381:TPHA_0J01230
uniprot id: G8BYK3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0A05270
gene id: 1071381:TPHA_0A05270
uniprot id: G8BNX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

1071381:TPHA 0E01300
gene id: 1071381:TPHA_0E01300
uniprot id: G8BTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

1071381:TPHA 0J01860
gene id: 1071381:TPHA_0J01860
uniprot id: G8BYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

1071381:TPHA 0C02800
gene id: 1071381:TPHA_0C02800
uniprot id: G8BRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

1071381:TPHA 0I01570
gene id: 1071381:TPHA_0I01570
uniprot id: G8BXN5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1071381:TPHA 0C03800
gene id: 1071381:TPHA_0C03800
uniprot id: G8BQM0
names: Similarity
messages: Belongs to the Luc7 family.

1071381:TPHA 0I02900
gene id: 1071381:TPHA_0I02900
uniprot id: G8BY13
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1071381:TPHA 0B00900
gene id: 1071381:TPHA_0B00900
uniprot id: G8BQG5
names: Similarity
messages: Belongs to the FBPase class 1 family.

1071381:TPHA 0C04445
gene id: 1071381:TPHA_0C04445
uniprot id: G8BQT3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071381:TPHA 0K00170
gene id: 1071381:TPHA_0K00170
uniprot id: G8BZ23
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

1071381:TPHA 0J00550
gene id: 1071381:TPHA_0J00550
uniprot id: G8BYD6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0F02160
gene id: 1071381:TPHA_0F02160
uniprot id: G8BVB6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

1071381:TPHA 0J01220
gene id: 1071381:TPHA_0J01220
uniprot id: G8BYK2
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1071381:TPHA 0P00690
gene id: 1071381:TPHA_0P00690
uniprot id: G8C249
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1071381:TPHA 0B04880
gene id: 1071381:TPHA_0B04880
uniprot id: G8BQ76
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.

1071381:TPHA 0G01940
gene id: 1071381:TPHA_0G01940
uniprot id: G8BVV2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

1071381:TPHA 0F01140
gene id: 1071381:TPHA_0F01140
uniprot id: G8BN65
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071381:TPHA 0C03320
gene id: 1071381:TPHA_0C03320
uniprot id: G8BRV8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1071381:TPHA 0B03640
gene id: 1071381:TPHA_0B03640
uniprot id: G8BPV4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

1071381:TPHA 0F00800
gene id: 1071381:TPHA_0F00800
uniprot id: G8BUY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0J00680
gene id: 1071381:TPHA_0J00680
uniprot id: G8BYE9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

1071381:TPHA 0F00520
gene id: 1071381:TPHA_0F00520
uniprot id: G8BUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

1071381:TPHA 0E01260
gene id: 1071381:TPHA_0E01260
uniprot id: G8BTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0J03030
gene id: 1071381:TPHA_0J03030
uniprot id: G8BY72
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

1071381:TPHA 0F02840
gene id: 1071381:TPHA_0F02840
uniprot id: G8BUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm

1071381:TPHA 0D03310
gene id: 1071381:TPHA_0D03310
uniprot id: G8BSZ6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E03260
gene id: 1071381:TPHA_0E03260
uniprot id: G8BU38
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

1071381:TPHA 0K00440
gene id: 1071381:TPHA_0K00440
uniprot id: G8BZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0L00570
gene id: 1071381:TPHA_0L00570
uniprot id: G8BZT5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1071381:TPHA 0A03550
gene id: 1071381:TPHA_0A03550
uniprot id: G8BNF3
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1071381:TPHA 0D00980
gene id: 1071381:TPHA_0D00980
uniprot id: G8BSB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0O01300
gene id: 1071381:TPHA_0O01300
uniprot id: G8C1S0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1071381:TPHA 0J02240
gene id: 1071381:TPHA_0J02240
uniprot id: G8BYV2
names: Similarity
messages: Belongs to the NAD kinase family.

1071381:TPHA 0B04190
gene id: 1071381:TPHA_0B04190
uniprot id: G8BQ08
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

1071381:TPHA 0G02580
gene id: 1071381:TPHA_0G02580
uniprot id: G8BW15
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1071381:TPHA 0J03200
gene id: 1071381:TPHA_0J03200
uniprot id: G8BY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0H01640
gene id: 1071381:TPHA_0H01640
uniprot id: G8BX66
names: Subcellular Location Annotation
messages: Golgi apparatus

1071381:TPHA 0H00880
gene id: 1071381:TPHA_0H00880
uniprot id: G8BWZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

1071381:TPHA 0E01370
gene id: 1071381:TPHA_0E01370
uniprot id: G8BTK4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1071381:TPHA 0D04530
gene id: 1071381:TPHA_0D04530
uniprot id: G8BS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: nuclear pore complex

1071381:TPHA 0C04560
gene id: 1071381:TPHA_0C04560
uniprot id: G8BQU4
names: Similarity
messages: Belongs to the MNN1/MNT family.

1071381:TPHA 0J02840
gene id: 1071381:TPHA_0J02840
uniprot id: G8BZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

1071381:TPHA 0G02380
gene id: 1071381:TPHA_0G02380
uniprot id: G8BVZ5
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

1071381:TPHA 0A03670
gene id: 1071381:TPHA_0A03670
uniprot id: G8BNG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1071381:TPHA 0A00530
gene id: 1071381:TPHA_0A00530
uniprot id: G8BML0
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

1071381:TPHA 0G02570
gene id: 1071381:TPHA_0G02570
uniprot id: G8BW14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071381:TPHA 0N00460
gene id: 1071381:TPHA_0N00460
uniprot id: G8C0Z8
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1071381:TPHA 0F01260
gene id: 1071381:TPHA_0F01260
uniprot id: G8BV29
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0E02840
gene id: 1071381:TPHA_0E02840
uniprot id: G8BTZ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0B02260
gene id: 1071381:TPHA_0B02260
uniprot id: G8BPG7
names: Similarity
messages: Belongs to the peptidase M16 family.

1071381:TPHA 0D01910
gene id: 1071381:TPHA_0D01910
uniprot id: G8BSK9
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

1071381:TPHA 0F03410
gene id: 1071381:TPHA_0F03410
uniprot id: G8BUN5
names: Similarity
messages: Belongs to the threonine aldolase family.

1071381:TPHA 0J00220
gene id: 1071381:TPHA_0J00220
uniprot id: G8BYA4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E04000
gene id: 1071381:TPHA_0E04000
uniprot id: G8BUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

1071381:TPHA 0B04140
gene id: 1071381:TPHA_0B04140
uniprot id: G8BQ03
names: Similarity
messages: Belongs to the SUI1 family.

1071381:TPHA 0A05580
gene id: 1071381:TPHA_0A05580
uniprot id: G8BP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071381:TPHA 0H00970
gene id: 1071381:TPHA_0H00970
uniprot id: G8BX01
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B02640
gene id: 1071381:TPHA_0B02640
uniprot id: G8BPK6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1071381:TPHA 0C01370
gene id: 1071381:TPHA_0C01370
uniprot id: G8BRB7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N01840
gene id: 1071381:TPHA_0N01840
uniprot id: G8C1D7
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

1071381:TPHA 0E01100
gene id: 1071381:TPHA_0E01100
uniprot id: G8BTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

1071381:TPHA 0C04240
gene id: 1071381:TPHA_0C04240
uniprot id: G8BQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1071381:TPHA 0L02300
gene id: 1071381:TPHA_0L02300
uniprot id: G8C0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

1071381:TPHA 0C00910
gene id: 1071381:TPHA_0C00910
uniprot id: G8BR71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

1071381:TPHA 0I00330
gene id: 1071381:TPHA_0I00330
uniprot id: G8BXB2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1071381:TPHA 0C02970
gene id: 1071381:TPHA_0C02970
uniprot id: G8BRS4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0B01590
gene id: 1071381:TPHA_0B01590
uniprot id: G8BPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0D00960
gene id: 1071381:TPHA_0D00960
uniprot id: G8BSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

1071381:TPHA 0G03350
gene id: 1071381:TPHA_0G03350
uniprot id: G8BW97
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1071381:TPHA 0O01590
gene id: 1071381:TPHA_0O01590
uniprot id: G8C1U8
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

1071381:TPHA 0I02710
gene id: 1071381:TPHA_0I02710
uniprot id: G8BXZ4
names: Similarity
messages: Belongs to the PAF1 family.

1071381:TPHA 0D04190
gene id: 1071381:TPHA_0D04190
uniprot id: G8BRX7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071381:TPHA 0P00660
gene id: 1071381:TPHA_0P00660
uniprot id: G8C246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Membrane

1071381:TPHA 0M01010
gene id: 1071381:TPHA_0M01010
uniprot id: G8C0G0
names: Similarity
messages: Belongs to the WrbA family.

1071381:TPHA 0F01910
gene id: 1071381:TPHA_0F01910
uniprot id: G8BV91
names: Similarity
messages: Belongs to the Tom22 family.

1071381:TPHA 0A03690
gene id: 1071381:TPHA_0A03690
uniprot id: G8BNG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

1071381:TPHA 0I02890
gene id: 1071381:TPHA_0I02890
uniprot id: G8BY12
names: Similarity
messages: Belongs to the PPP4R2 family.

1071381:TPHA 0A04410
gene id: 1071381:TPHA_0A04410
uniprot id: G8BQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0J02670
gene id: 1071381:TPHA_0J02670
uniprot id: G8BYZ5
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

1071381:TPHA 0K00200
gene id: 1071381:TPHA_0K00200
uniprot id: G8BZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.

1071381:TPHA 0E00430
gene id: 1071381:TPHA_0E00430
uniprot id: G8BTB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0H01660
gene id: 1071381:TPHA_0H01660
uniprot id: G8BX68
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1071381:TPHA 0D02190
gene id: 1071381:TPHA_0D02190
uniprot id: G8BSN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

1071381:TPHA 0I02940
gene id: 1071381:TPHA_0I02940
uniprot id: G8BY17
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

1071381:TPHA 0I02380
gene id: 1071381:TPHA_0I02380
uniprot id: G8BXW3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1071381:TPHA 0L02010
gene id: 1071381:TPHA_0L02010
uniprot id: G8C075
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0I01400
gene id: 1071381:TPHA_0I01400
uniprot id: G8BXL8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1071381:TPHA 0J02050
gene id: 1071381:TPHA_0J02050
uniprot id: G8BYT3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1071381:TPHA 0D02720
gene id: 1071381:TPHA_0D02720
uniprot id: G8BST7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

1071381:TPHA 0D01760
gene id: 1071381:TPHA_0D01760
uniprot id: G8BSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

1071381:TPHA 0C02590
gene id: 1071381:TPHA_0C02590
uniprot id: G8BRN6
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

1071381:TPHA 0A01230
gene id: 1071381:TPHA_0A01230
uniprot id: G8BMS9
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

1071381:TPHA 0L00410
gene id: 1071381:TPHA_0L00410
uniprot id: G8BZR9
names: Similarity
messages: Belongs to the MAK16 family.

1071381:TPHA 0B00890
gene id: 1071381:TPHA_0B00890
uniprot id: G8BQG4
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

1071381:TPHA 0N01530
gene id: 1071381:TPHA_0N01530
uniprot id: G8C1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

1071381:TPHA 0H02250
gene id: 1071381:TPHA_0H02250
uniprot id: G8BWH8
names: Similarity
messages: Belongs to the threonine synthase family.

1071381:TPHA 0H02080
gene id: 1071381:TPHA_0H02080
uniprot id: G8BWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP1 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression.
messages: spindle pole body

1071381:TPHA 0A02350
gene id: 1071381:TPHA_0A02350
uniprot id: G8BN39
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0H02100
gene id: 1071381:TPHA_0H02100
uniprot id: G8BWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

1071381:TPHA 0A01440
gene id: 1071381:TPHA_0A01440
uniprot id: G8BMU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1071381:TPHA 0H00690
gene id: 1071381:TPHA_0H00690
uniprot id: G8BWX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

1071381:TPHA 0E03810
gene id: 1071381:TPHA_0E03810
uniprot id: G8BU92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0J02530
gene id: 1071381:TPHA_0J02530
uniprot id: G8BYY1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

1071381:TPHA 0A01640
gene id: 1071381:TPHA_0A01640
uniprot id: G8BMW9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D02240
gene id: 1071381:TPHA_0D02240
uniprot id: G8BSP1
names: Similarity
messages: Belongs to the TCF25 family.

1071381:TPHA 0J01730
gene id: 1071381:TPHA_0J01730
uniprot id: G8BYQ2
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0I02840
gene id: 1071381:TPHA_0I02840
uniprot id: G8BY07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071381:TPHA 0A04160
gene id: 1071381:TPHA_0A04160
uniprot id: G8BNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1071381:TPHA 0H00390
gene id: 1071381:TPHA_0H00390
uniprot id: G8BWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

1071381:TPHA 0C04170
gene id: 1071381:TPHA_0C04170
uniprot id: G8BQQ5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1071381:TPHA 0B04470
gene id: 1071381:TPHA_0B04470
uniprot id: G8BQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0A03150
gene id: 1071381:TPHA_0A03150
uniprot id: G8BNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

1071381:TPHA 0M01530
gene id: 1071381:TPHA_0M01530
uniprot id: G8C0L3
names: Similarity
messages: Belongs to the FES1 family.

1071381:TPHA 0B03510
gene id: 1071381:TPHA_0B03510
uniprot id: G8BPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1071381:TPHA 0C01780
gene id: 1071381:TPHA_0C01780
uniprot id: G8BRF8
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0G03610
gene id: 1071381:TPHA_0G03610
uniprot id: G8BWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1071381:TPHA 0C02510
gene id: 1071381:TPHA_0C02510
uniprot id: G8BRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

1071381:TPHA 0G03190
gene id: 1071381:TPHA_0G03190
uniprot id: G8BW81
names: Similarity
messages: Belongs to the peptidase M18 family.

1071381:TPHA 0N01490
gene id: 1071381:TPHA_0N01490
uniprot id: G8C1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

1071381:TPHA 0C00840
gene id: 1071381:TPHA_0C00840
uniprot id: G8BR64
names: Similarity
messages: Belongs to the peptidase A1 family.

1071381:TPHA 0L01930
gene id: 1071381:TPHA_0L01930
uniprot id: G8C068
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AEP1 family.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.

1071381:TPHA 0J00490
gene id: 1071381:TPHA_0J00490
uniprot id: G8BYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

1071381:TPHA 0J00400
gene id: 1071381:TPHA_0J00400
uniprot id: G8BYC1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0F00920
gene id: 1071381:TPHA_0F00920
uniprot id: G8BUZ6
names: Similarity
messages: Belongs to the TACO1 family.

1071381:TPHA 0J00720
gene id: 1071381:TPHA_0J00720
uniprot id: G8BYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

1071381:TPHA 0G00840
gene id: 1071381:TPHA_0G00840
uniprot id: G8BVJ2
names: Similarity
messages: Belongs to the PPC synthetase family.

1071381:TPHA 0J02140
gene id: 1071381:TPHA_0J02140
uniprot id: G8BYU2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

1071381:TPHA 0I03060
gene id: 1071381:TPHA_0I03060
uniprot id: G8BY29
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

1071381:TPHA 0G03100
gene id: 1071381:TPHA_0G03100
uniprot id: G8BW73
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0A02430
gene id: 1071381:TPHA_0A02430
uniprot id: G8BN48
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

1071381:TPHA 0J01410
gene id: 1071381:TPHA_0J01410
uniprot id: G8BYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

1071381:TPHA 0A05930
gene id: 1071381:TPHA_0A05930
uniprot id: G8BP39
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A03290
gene id: 1071381:TPHA_0A03290
uniprot id: G8BNC8
names: Similarity
messages: Belongs to the IMPACT family.

1071381:TPHA 0O01790
gene id: 1071381:TPHA_0O01790
uniprot id: G8C1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0G02030
gene id: 1071381:TPHA_0G02030
uniprot id: G8BVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

1071381:TPHA 0D00240
gene id: 1071381:TPHA_0D00240
uniprot id: G8BS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0E00870
gene id: 1071381:TPHA_0E00870
uniprot id: G8BTF4
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0I01650
gene id: 1071381:TPHA_0I01650
uniprot id: G8BXP1
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071381:TPHA 0E03010
gene id: 1071381:TPHA_0E03010
uniprot id: G8BU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071381:TPHA 0A00190
gene id: 1071381:TPHA_0A00190
uniprot id: G8BMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

1071381:TPHA 0E00200
gene id: 1071381:TPHA_0E00200
uniprot id: G8BT89
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1071381:TPHA 0D00640
gene id: 1071381:TPHA_0D00640
uniprot id: G8BS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1071381:TPHA 0J01180
gene id: 1071381:TPHA_0J01180
uniprot id: G8BYJ8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

1071381:TPHA 0D00590
gene id: 1071381:TPHA_0D00590
uniprot id: G8BS82
names: Similarity
messages: Belongs to the BLM10 family.

1071381:TPHA 0P00340
gene id: 1071381:TPHA_0P00340
uniprot id: G8C214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

1071381:TPHA 0D03600
gene id: 1071381:TPHA_0D03600
uniprot id: G8BT24
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1071381:TPHA 0G01600
gene id: 1071381:TPHA_0G01600
uniprot id: G8BVR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

1071381:TPHA 0G03680
gene id: 1071381:TPHA_0G03680
uniprot id: G8BWD0
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

1071381:TPHA 0L00930
gene id: 1071381:TPHA_0L00930
uniprot id: G8BZX2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071381:TPHA 0D02630
gene id: 1071381:TPHA_0D02630
uniprot id: G8BSS9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C00870
gene id: 1071381:TPHA_0C00870
uniprot id: G8BR67
names: Similarity
messages: Belongs to the dopey family.

1071381:TPHA 0C00860
gene id: 1071381:TPHA_0C00860
uniprot id: G8BR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

1071381:TPHA 0C01580
gene id: 1071381:TPHA_0C01580
uniprot id: G8BRD8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

1071381:TPHA 0H01460
gene id: 1071381:TPHA_0H01460
uniprot id: G8BX48
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0M00630
gene id: 1071381:TPHA_0M00630
uniprot id: G8C0C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0B00590
gene id: 1071381:TPHA_0B00590
uniprot id: G8BQD4
names: Similarity
messages: Belongs to the WD repeat coronin family.

1071381:TPHA 0D03710
gene id: 1071381:TPHA_0D03710
uniprot id: G8BT35
names: Similarity
messages: Belongs to the uridine kinase family.

1071381:TPHA 0P00890
gene id: 1071381:TPHA_0P00890
uniprot id: G8C269
names: Similarity
messages: Belongs to the Rho GDI family.

1071381:TPHA 0C00100
gene id: 1071381:TPHA_0C00100
uniprot id: G8BQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

1071381:TPHA 0F02970
gene id: 1071381:TPHA_0F02970
uniprot id: G8BUJ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1071381:TPHA 0C04020
gene id: 1071381:TPHA_0C04020
uniprot id: G8BQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0J03220
gene id: 1071381:TPHA_0J03220
uniprot id: G8BY90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1071381:TPHA 0H00280
gene id: 1071381:TPHA_0H00280
uniprot id: G8BWT4
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0I00940
gene id: 1071381:TPHA_0I00940
uniprot id: G8BXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

1071381:TPHA 0A03810
gene id: 1071381:TPHA_0A03810
uniprot id: G8BNH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

1071381:TPHA 0N01210
gene id: 1071381:TPHA_0N01210
uniprot id: G8C174
names: Subcellular Location Annotation
messages: nuclear pore complex

1071381:TPHA 0D04350
gene id: 1071381:TPHA_0D04350
uniprot id: G8BRZ4
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0P00980
gene id: 1071381:TPHA_0P00980
uniprot id: G8C278
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0K01070
gene id: 1071381:TPHA_0K01070
uniprot id: G8BZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

1071381:TPHA 0G03460
gene id: 1071381:TPHA_0G03460
uniprot id: G8BWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0H02490
gene id: 1071381:TPHA_0H02490
uniprot id: G8BWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071381:TPHA 0B04210
gene id: 1071381:TPHA_0B04210
uniprot id: G8BQ10
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

1071381:TPHA 0B03050
gene id: 1071381:TPHA_0B03050
uniprot id: G8BPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

1071381:TPHA 0C02000
gene id: 1071381:TPHA_0C02000
uniprot id: G8BRH9
names: Similarity
messages: Belongs to the MGMT family.

1071381:TPHA 0E00450
gene id: 1071381:TPHA_0E00450
uniprot id: G8BTB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1071381:TPHA 0H02240
gene id: 1071381:TPHA_0H02240
uniprot id: G8BWH7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H02130
gene id: 1071381:TPHA_0H02130
uniprot id: G8BWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0O00370
gene id: 1071381:TPHA_0O00370
uniprot id: G8C1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071381:TPHA 0P01380
gene id: 1071381:TPHA_0P01380
uniprot id: G8C2B8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

1071381:TPHA 0G02280
gene id: 1071381:TPHA_0G02280
uniprot id: G8BVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

1071381:TPHA 0M00470
gene id: 1071381:TPHA_0M00470
uniprot id: G8C0W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

1071381:TPHA 0B02550
gene id: 1071381:TPHA_0B02550
uniprot id: G8BPJ7
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0H03100
gene id: 1071381:TPHA_0H03100
uniprot id: G8BWR2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0E03240
gene id: 1071381:TPHA_0E03240
uniprot id: G8BU36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0L02080
gene id: 1071381:TPHA_0L02080
uniprot id: G8C082
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

1071381:TPHA 0K00360
gene id: 1071381:TPHA_0K00360
uniprot id: G8BZ42
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O01100
gene id: 1071381:TPHA_0O01100
uniprot id: G8C1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

1071381:TPHA 0J02410
gene id: 1071381:TPHA_0J02410
uniprot id: G8BYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

1071381:TPHA 0P01370
gene id: 1071381:TPHA_0P01370
uniprot id: G8C2B7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

1071381:TPHA 0D02660
gene id: 1071381:TPHA_0D02660
uniprot id: G8BST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

1071381:TPHA 0A02550
gene id: 1071381:TPHA_0A02550
uniprot id: G8BN60
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1071381:TPHA 0H02110
gene id: 1071381:TPHA_0H02110
uniprot id: G8BWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS27 family.
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0G02680
gene id: 1071381:TPHA_0G02680
uniprot id: G8BW27
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071381:TPHA 0G00500
gene id: 1071381:TPHA_0G00500
uniprot id: G8BVF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0B01850
gene id: 1071381:TPHA_0B01850
uniprot id: G8BPC6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1071381:TPHA 0H01370
gene id: 1071381:TPHA_0H01370
uniprot id: G8BX39
names: Similarity
messages: Belongs to the RNase Z family.

1071381:TPHA 0D02060
gene id: 1071381:TPHA_0D02060
uniprot id: G8BSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0B04810
gene id: 1071381:TPHA_0B04810
uniprot id: G8BQ69
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0E00330
gene id: 1071381:TPHA_0E00330
uniprot id: G8BTA1
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

1071381:TPHA 0H00190
gene id: 1071381:TPHA_0H00190
uniprot id: G8BWS6
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

1071381:TPHA 0L01580
gene id: 1071381:TPHA_0L01580
uniprot id: G8C033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

1071381:TPHA 0B02470
gene id: 1071381:TPHA_0B02470
uniprot id: G8BPI9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0M00330
gene id: 1071381:TPHA_0M00330
uniprot id: G8C0U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

1071381:TPHA 0C00820
gene id: 1071381:TPHA_0C00820
uniprot id: G8BR62
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

1071381:TPHA 0D03360
gene id: 1071381:TPHA_0D03360
uniprot id: G8BT01
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1071381:TPHA 0K01610
gene id: 1071381:TPHA_0K01610
uniprot id: G8BZG6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1071381:TPHA 0G02780
gene id: 1071381:TPHA_0G02780
uniprot id: G8BW38
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

1071381:TPHA 0N00980
gene id: 1071381:TPHA_0N00980
uniprot id: G8C151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

1071381:TPHA 0J01780
gene id: 1071381:TPHA_0J01780
uniprot id: G8BYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

1071381:TPHA 0A00600
gene id: 1071381:TPHA_0A00600
uniprot id: G8BML7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

1071381:TPHA 0P01460
gene id: 1071381:TPHA_0P01460
uniprot id: G8C2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

1071381:TPHA 0G02240
gene id: 1071381:TPHA_0G02240
uniprot id: G8BVY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1071381:TPHA 0C02070
gene id: 1071381:TPHA_0C02070
uniprot id: G8BRI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

1071381:TPHA 0A00480
gene id: 1071381:TPHA_0A00480
uniprot id: G8BMK5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1071381:TPHA 0C00400
gene id: 1071381:TPHA_0C00400
uniprot id: G8BR21
names: Subcellular Location Annotation
messages: Vacuole

1071381:TPHA 0E00240
gene id: 1071381:TPHA_0E00240
uniprot id: G8BS20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

1071381:TPHA 0N00260
gene id: 1071381:TPHA_0N00260
uniprot id: G8C0X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1071381:TPHA 0B01680
gene id: 1071381:TPHA_0B01680
uniprot id: G8BPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

1071381:TPHA 0J02110
gene id: 1071381:TPHA_0J02110
uniprot id: G8BYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

1071381:TPHA 0H00200
gene id: 1071381:TPHA_0H00200
uniprot id: G8BWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

1071381:TPHA 0B01900
gene id: 1071381:TPHA_0B01900
uniprot id: G8BPD1
names: Similarity
messages: Belongs to the DOCK family.

1071381:TPHA 0A00880
gene id: 1071381:TPHA_0A00880
uniprot id: G8BMP5
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

1071381:TPHA 0A00140
gene id: 1071381:TPHA_0A00140
uniprot id: G8BMH1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1071381:TPHA 0C01810
gene id: 1071381:TPHA_0C01810
uniprot id: G8BRG1
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0N01410
gene id: 1071381:TPHA_0N01410
uniprot id: G8C194
names: Similarity
messages: Belongs to the EIS1 family.

1071381:TPHA 0F01410
gene id: 1071381:TPHA_0F01410
uniprot id: G8BV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0E03640
gene id: 1071381:TPHA_0E03640
uniprot id: G8BU75
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

1071381:TPHA 0P00410
gene id: 1071381:TPHA_0P00410
uniprot id: G8C221
names: Similarity
messages: Belongs to the patched family.

1071381:TPHA 0J02040
gene id: 1071381:TPHA_0J02040
uniprot id: G8BYT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

1071381:TPHA 0M00850
gene id: 1071381:TPHA_0M00850
uniprot id: G8C0E5
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1071381:TPHA 0E02580
gene id: 1071381:TPHA_0E02580
uniprot id: G8BTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

1071381:TPHA 0D02090
gene id: 1071381:TPHA_0D02090
uniprot id: G8BSM6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1071381:TPHA 0I03300
gene id: 1071381:TPHA_0I03300
uniprot id: G8BY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

1071381:TPHA 0C03660
gene id: 1071381:TPHA_0C03660
uniprot id: G8BQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F00310
gene id: 1071381:TPHA_0F00310
uniprot id: G8BUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0I01040
gene id: 1071381:TPHA_0I01040
uniprot id: G8BXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

1071381:TPHA 0A03900
gene id: 1071381:TPHA_0A03900
uniprot id: G8BNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0D01840
gene id: 1071381:TPHA_0D01840
uniprot id: G8BSK2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1071381:TPHA 0N00860
gene id: 1071381:TPHA_0N00860
uniprot id: G8C139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

1071381:TPHA 0F01490
gene id: 1071381:TPHA_0F01490
uniprot id: G8BV51
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

1071381:TPHA 0G03030
gene id: 1071381:TPHA_0G03030
uniprot id: G8BW66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrial mRNA stabilization factor.
messages: Mitochondrion inner membrane

1071381:TPHA 0G00440
gene id: 1071381:TPHA_0G00440
uniprot id: G8BVF2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0K00310
gene id: 1071381:TPHA_0K00310
uniprot id: G8BZ37
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

1071381:TPHA 0A00610
gene id: 1071381:TPHA_0A00610
uniprot id: G8BML8
names: Similarity
messages: Belongs to the AHA1 family.

1071381:TPHA 0L02130
gene id: 1071381:TPHA_0L02130
uniprot id: G8C086
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

1071381:TPHA 0D01560
gene id: 1071381:TPHA_0D01560
uniprot id: G8BSH5
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

1071381:TPHA 0I00880
gene id: 1071381:TPHA_0I00880
uniprot id: G8BXG6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

1071381:TPHA 0J00970
gene id: 1071381:TPHA_0J00970
uniprot id: G8BYH7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1071381:TPHA 0D01270
gene id: 1071381:TPHA_0D01270
uniprot id: G8BSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

1071381:TPHA 0B03410
gene id: 1071381:TPHA_0B03410
uniprot id: G8BPT0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0L02160
gene id: 1071381:TPHA_0L02160
uniprot id: G8C089
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

1071381:TPHA 0M01240
gene id: 1071381:TPHA_0M01240
uniprot id: G8C0I4
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

1071381:TPHA 0I01850
gene id: 1071381:TPHA_0I01850
uniprot id: G8BXR1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1071381:TPHA 0A02480
gene id: 1071381:TPHA_0A02480
uniprot id: G8BN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG14 family.
messages: Vacuole membrane

1071381:TPHA 0C00770
gene id: 1071381:TPHA_0C00770
uniprot id: G8BR57
names: Similarity
messages: Belongs to the SLX4 family.

1071381:TPHA 0I02370
gene id: 1071381:TPHA_0I02370
uniprot id: G8BXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

1071381:TPHA 0B00770
gene id: 1071381:TPHA_0B00770
uniprot id: G8BQF2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0B01910
gene id: 1071381:TPHA_0B01910
uniprot id: G8BPD2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0D04600
gene id: 1071381:TPHA_0D04600
uniprot id: G8BS20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

1071381:TPHA 0A03970
gene id: 1071381:TPHA_0A03970
uniprot id: G8BNJ5
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

1071381:TPHA 0K00920
gene id: 1071381:TPHA_0K00920
uniprot id: G8BZ98
names: Similarity
messages: Belongs to the RutC family.

1071381:TPHA 0H00600
gene id: 1071381:TPHA_0H00600
uniprot id: G8BWW6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

1071381:TPHA 0F02170
gene id: 1071381:TPHA_0F02170
uniprot id: G8BVB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.

1071381:TPHA 0O01970
gene id: 1071381:TPHA_0O01970
uniprot id: G8C1Y5
names: Similarity
messages: Belongs to the globin family.

1071381:TPHA 0O00280
gene id: 1071381:TPHA_0O00280
uniprot id: G8C1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

1071381:TPHA 0B03420
gene id: 1071381:TPHA_0B03420
uniprot id: G8BPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

1071381:TPHA 0O00930
gene id: 1071381:TPHA_0O00930
uniprot id: G8C1N4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G02610
gene id: 1071381:TPHA_0G02610
uniprot id: G8BW20
names: Similarity
messages: Belongs to the SIP5 family.

1071381:TPHA 0D01520
gene id: 1071381:TPHA_0D01520
uniprot id: G8BSH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

1071381:TPHA 0J01320
gene id: 1071381:TPHA_0J01320
uniprot id: G8BYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

1071381:TPHA 0E00290
gene id: 1071381:TPHA_0E00290
uniprot id: G8BT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0G03380
gene id: 1071381:TPHA_0G03380
uniprot id: G8BWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071381:TPHA 0K00950
gene id: 1071381:TPHA_0K00950
uniprot id: G8BZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071381:TPHA 0E02140
gene id: 1071381:TPHA_0E02140
uniprot id: G8BTS8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

1071381:TPHA 0P00530
gene id: 1071381:TPHA_0P00530
uniprot id: G8C233
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1071381:TPHA 0G00320
gene id: 1071381:TPHA_0G00320
uniprot id: G8BVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0K01270
gene id: 1071381:TPHA_0K01270
uniprot id: G8BZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071381:TPHA 0O01040
gene id: 1071381:TPHA_0O01040
uniprot id: G8C1P5
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

1071381:TPHA 0B04680
gene id: 1071381:TPHA_0B04680
uniprot id: G8BQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

1071381:TPHA 0A01480
gene id: 1071381:TPHA_0A01480
uniprot id: G8BMV3
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

1071381:TPHA 0H02700
gene id: 1071381:TPHA_0H02700
uniprot id: G8BWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1071381:TPHA 0I00460
gene id: 1071381:TPHA_0I00460
uniprot id: G8BXC4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D02430
gene id: 1071381:TPHA_0D02430
uniprot id: G8BSQ9
names: Similarity
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Homodimer.

1071381:TPHA 0G03040
gene id: 1071381:TPHA_0G03040
uniprot id: G8BW67
names: Similarity
messages: Belongs to the KTI12 family.

1071381:TPHA 0A05220
gene id: 1071381:TPHA_0A05220
uniprot id: G8BNW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1071381:TPHA 0H02990
gene id: 1071381:TPHA_0H02990
uniprot id: G8BWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

1071381:TPHA 0B00990
gene id: 1071381:TPHA_0B00990
uniprot id: G8BQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0G00880
gene id: 1071381:TPHA_0G00880
uniprot id: G8BVJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1071381:TPHA 0P01680
gene id: 1071381:TPHA_0P01680
uniprot id: G8C2E8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1071381:TPHA 0A02610
gene id: 1071381:TPHA_0A02610
uniprot id: G8BN65
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

1071381:TPHA 0C02360
gene id: 1071381:TPHA_0C02360
uniprot id: G8BRL3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

1071381:TPHA 0C02170
gene id: 1071381:TPHA_0C02170
uniprot id: G8BRJ5
names: Similarity
messages: Belongs to the AHA1 family.

1071381:TPHA 0C04610
gene id: 1071381:TPHA_0C04610
uniprot id: G8BQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

1071381:TPHA 0O00920
gene id: 1071381:TPHA_0O00920
uniprot id: G8C1N3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0G00330
gene id: 1071381:TPHA_0G00330
uniprot id: G8BVE3
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

1071381:TPHA 0H01290
gene id: 1071381:TPHA_0H01290
uniprot id: G8BX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: spindle pole

1071381:TPHA 0F00150
gene id: 1071381:TPHA_0F00150
uniprot id: G8BUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

1071381:TPHA 0H02570
gene id: 1071381:TPHA_0H02570
uniprot id: G8BWK9
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

1071381:TPHA 0D00250
gene id: 1071381:TPHA_0D00250
uniprot id: G8BS48
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

1071381:TPHA 0F02650
gene id: 1071381:TPHA_0F02650
uniprot id: G8BUF9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1071381:TPHA 0I03270
gene id: 1071381:TPHA_0I03270
uniprot id: G8BY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

1071381:TPHA 0F01660
gene id: 1071381:TPHA_0F01660
uniprot id: G8BV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0C03450
gene id: 1071381:TPHA_0C03450
uniprot id: G8BRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

1071381:TPHA 0E03040
gene id: 1071381:TPHA_0E03040
uniprot id: G8BU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

1071381:TPHA 0J02100
gene id: 1071381:TPHA_0J02100
uniprot id: G8BYT8
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

1071381:TPHA 0J02600
gene id: 1071381:TPHA_0J02600
uniprot id: G8BYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

1071381:TPHA 0I01910
gene id: 1071381:TPHA_0I01910
uniprot id: G8BXR7
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0I01820
gene id: 1071381:TPHA_0I01820
uniprot id: G8BXQ8
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

1071381:TPHA 0B01960
gene id: 1071381:TPHA_0B01960
uniprot id: G8BPD7
names: Similarity
messages: Belongs to the Mo25 family.

1071381:TPHA 0N01860
gene id: 1071381:TPHA_0N01860
uniprot id: G8C1D9
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

1071381:TPHA 0G01880
gene id: 1071381:TPHA_0G01880
uniprot id: G8BVU6
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

1071381:TPHA 0D01200
gene id: 1071381:TPHA_0D01200
uniprot id: G8BSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

1071381:TPHA 0A01750
gene id: 1071381:TPHA_0A01750
uniprot id: G8BMY0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B02700
gene id: 1071381:TPHA_0B02700
uniprot id: G8BPL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

1071381:TPHA 0B01530
gene id: 1071381:TPHA_0B01530
uniprot id: G8BP95
names: Similarity
messages: Belongs to the WD repeat mio family.

1071381:TPHA 0P00170
gene id: 1071381:TPHA_0P00170
uniprot id: G8C1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

1071381:TPHA 0E03700
gene id: 1071381:TPHA_0E03700
uniprot id: G8BU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

1071381:TPHA 0J03020
gene id: 1071381:TPHA_0J03020
uniprot id: G8BY71
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F03660
gene id: 1071381:TPHA_0F03660
uniprot id: G8BUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0N01640
gene id: 1071381:TPHA_0N01640
uniprot id: G8C1B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

1071381:TPHA 0E03410
gene id: 1071381:TPHA_0E03410
uniprot id: G8BU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0A00710
gene id: 1071381:TPHA_0A00710
uniprot id: G8BMM8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

1071381:TPHA 0O00590
gene id: 1071381:TPHA_0O00590
uniprot id: G8C1K1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0G00290
gene id: 1071381:TPHA_0G00290
uniprot id: G8BVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

1071381:TPHA 0I01960
gene id: 1071381:TPHA_0I01960
uniprot id: G8BXS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

1071381:TPHA 0A05780
gene id: 1071381:TPHA_0A05780
uniprot id: G8BP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1071381:TPHA 0M00230
gene id: 1071381:TPHA_0M00230
uniprot id: G8C0U0
names: Similarity
messages: Belongs to the peptidase S8 family.

1071381:TPHA 0B03500
gene id: 1071381:TPHA_0B03500
uniprot id: G8BPT9
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0I03010
gene id: 1071381:TPHA_0I03010
uniprot id: G8BY24
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

1071381:TPHA 0A05550
gene id: 1071381:TPHA_0A05550
uniprot id: G8BP01
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1071381:TPHA 0A05450
gene id: 1071381:TPHA_0A05450
uniprot id: G8BNZ1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0O00740
gene id: 1071381:TPHA_0O00740
uniprot id: G8C1L5
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

1071381:TPHA 0B04850
gene id: 1071381:TPHA_0B04850
uniprot id: G8BQ73
names: Similarity
messages: Belongs to the hexokinase family.

1071381:TPHA 0B01760
gene id: 1071381:TPHA_0B01760
uniprot id: G8BPB8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1071381:TPHA 0H00750
gene id: 1071381:TPHA_0H00750
uniprot id: G8BWY1
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0L00840
gene id: 1071381:TPHA_0L00840
uniprot id: G8BZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

1071381:TPHA 0K00690
gene id: 1071381:TPHA_0K00690
uniprot id: G8BZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
messages: telomere

1071381:TPHA 0K00960
gene id: 1071381:TPHA_0K00960
uniprot id: G8BZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

1071381:TPHA 0H02330
gene id: 1071381:TPHA_0H02330
uniprot id: G8BWI6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L01720
gene id: 1071381:TPHA_0L01720
uniprot id: G8C047
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C03830
gene id: 1071381:TPHA_0C03830
uniprot id: G8BQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

1071381:TPHA 0H02120
gene id: 1071381:TPHA_0H02120
uniprot id: G8BWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

1071381:TPHA 0D01680
gene id: 1071381:TPHA_0D01680
uniprot id: G8BSI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0H01260
gene id: 1071381:TPHA_0H01260
uniprot id: G8BX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

1071381:TPHA 0A01350
gene id: 1071381:TPHA_0A01350
uniprot id: G8BMU0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1071381:TPHA 0C00580
gene id: 1071381:TPHA_0C00580
uniprot id: G8BR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

1071381:TPHA 0G02720
gene id: 1071381:TPHA_0G02720
uniprot id: G8BW31
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071381:TPHA 0J01420
gene id: 1071381:TPHA_0J01420
uniprot id: G8BYM2
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

1071381:TPHA 0P00190
gene id: 1071381:TPHA_0P00190
uniprot id: G8C1Z9
names: Similarity
messages: Belongs to the multicopper oxidase family.

1071381:TPHA 0A05590
gene id: 1071381:TPHA_0A05590
uniprot id: G8BP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

1071381:TPHA 0G03480
gene id: 1071381:TPHA_0G03480
uniprot id: G8BWB0
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

1071381:TPHA 0M00480
gene id: 1071381:TPHA_0M00480
uniprot id: G8C0W2
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0N00700
gene id: 1071381:TPHA_0N00700
uniprot id: G8C123
names: Similarity
messages: Belongs to the DEAD box helicase family.

1071381:TPHA 0C04660
gene id: 1071381:TPHA_0C04660
uniprot id: G8BQV4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1071381:TPHA 0E03930
gene id: 1071381:TPHA_0E03930
uniprot id: G8BUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071381:TPHA 0D00950
gene id: 1071381:TPHA_0D00950
uniprot id: G8BSB5
names: Subcellular Location Annotation
messages: Nucleus membrane

1071381:TPHA 0E00260
gene id: 1071381:TPHA_0E00260
uniprot id: G8BT94
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1071381:TPHA 0D02570
gene id: 1071381:TPHA_0D02570
uniprot id: G8BSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

1071381:TPHA 0A01860
gene id: 1071381:TPHA_0A01860
uniprot id: G8BMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

1071381:TPHA 0I00360
gene id: 1071381:TPHA_0I00360
uniprot id: G8BXB5
names: Similarity
messages: Belongs to the PTH family.

1071381:TPHA 0O00730
gene id: 1071381:TPHA_0O00730
uniprot id: G8C1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

1071381:TPHA 0C02640
gene id: 1071381:TPHA_0C02640
uniprot id: G8BRP1
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

1071381:TPHA 0I02270
gene id: 1071381:TPHA_0I02270
uniprot id: G8BXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071381:TPHA 0C04530
gene id: 1071381:TPHA_0C04530
uniprot id: G8BQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

1071381:TPHA 0I01760
gene id: 1071381:TPHA_0I01760
uniprot id: G8BXQ2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E01000
gene id: 1071381:TPHA_0E01000
uniprot id: G8BTG6
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1071381:TPHA 0M01310
gene id: 1071381:TPHA_0M01310
uniprot id: G8C0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0B04050
gene id: 1071381:TPHA_0B04050
uniprot id: G8C1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

1071381:TPHA 0M01320
gene id: 1071381:TPHA_0M01320
uniprot id: G8C0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

1071381:TPHA 0C02880
gene id: 1071381:TPHA_0C02880
uniprot id: G8BRR5
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

1071381:TPHA 0G01720
gene id: 1071381:TPHA_0G01720
uniprot id: G8BVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

1071381:TPHA 0H03050
gene id: 1071381:TPHA_0H03050
uniprot id: G8BWQ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

1071381:TPHA 0D02350
gene id: 1071381:TPHA_0D02350
uniprot id: G8BSQ1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

1071381:TPHA 0A05200
gene id: 1071381:TPHA_0A05200
uniprot id: G8BNW7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1071381:TPHA 0O02000
gene id: 1071381:TPHA_0O02000
uniprot id: G8C1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1071381:TPHA 0B01190
gene id: 1071381:TPHA_0B01190
uniprot id: G8BP60
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0D01120
gene id: 1071381:TPHA_0D01120
uniprot id: G8BSD2
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O01120
gene id: 1071381:TPHA_0O01120
uniprot id: G8C1Q3
names: Similarity
messages: Belongs to the protein kinase superfamily.

1071381:TPHA 0B00820
gene id: 1071381:TPHA_0B00820
uniprot id: G8BQF7
names: Similarity
messages: Belongs to the RAD52 family.

1071381:TPHA 0C02180
gene id: 1071381:TPHA_0C02180
uniprot id: G8BRJ6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A05980
gene id: 1071381:TPHA_0A05980
uniprot id: G8BP44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

1071381:TPHA 0B02740
gene id: 1071381:TPHA_0B02740
uniprot id: G8BPL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

1071381:TPHA 0E03550
gene id: 1071381:TPHA_0E03550
uniprot id: G8BU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071381:TPHA 0C02010
gene id: 1071381:TPHA_0C02010
uniprot id: G8BRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0F03340
gene id: 1071381:TPHA_0F03340
uniprot id: G8BUM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1071381:TPHA 0A00950
gene id: 1071381:TPHA_0A00950
uniprot id: G8BMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

1071381:TPHA 0M00460
gene id: 1071381:TPHA_0M00460
uniprot id: G8C0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

1071381:TPHA 0B02420
gene id: 1071381:TPHA_0B02420
uniprot id: G8BPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

1071381:TPHA 0K00350
gene id: 1071381:TPHA_0K00350
uniprot id: G8BZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0A06080
gene id: 1071381:TPHA_0A06080
uniprot id: G8BP53
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H00980
gene id: 1071381:TPHA_0H00980
uniprot id: G8BX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

1071381:TPHA 0A01320
gene id: 1071381:TPHA_0A01320
uniprot id: G8BMT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

1071381:TPHA 0J00460
gene id: 1071381:TPHA_0J00460
uniprot id: G8BYC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

1071381:TPHA 0E01020
gene id: 1071381:TPHA_0E01020
uniprot id: G8BTG8
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071381:TPHA 0D04380
gene id: 1071381:TPHA_0D04380
uniprot id: G8BRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1071381:TPHA 0A01730
gene id: 1071381:TPHA_0A01730
uniprot id: G8BMX8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1071381:TPHA 0G02885
gene id: 1071381:TPHA_0G02885
uniprot id: G8BW51
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1071381:TPHA 0C04980
gene id: 1071381:TPHA_0C04980
uniprot id: G8BQY4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0O01510
gene id: 1071381:TPHA_0O01510
uniprot id: G8C1U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0M01770
gene id: 1071381:TPHA_0M01770
uniprot id: G8C0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

1071381:TPHA 0D03070
gene id: 1071381:TPHA_0D03070
uniprot id: G8BSX2
names: Similarity
messages: Belongs to the cyclin family.

1071381:TPHA 0A03850
gene id: 1071381:TPHA_0A03850
uniprot id: G8BNI3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0H00950
gene id: 1071381:TPHA_0H00950
uniprot id: G8BWZ9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1071381:TPHA 0E01990
gene id: 1071381:TPHA_0E01990
uniprot id: G8BTR3
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

1071381:TPHA 0O00120
gene id: 1071381:TPHA_0O00120
uniprot id: G8C1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YRA1 family.
messages: Involved in export of poly(A) mRNAs from the nucleus. Recruited to the coding sequences as well as poly-A sites of active genes.
messages: Nucleus

1071381:TPHA 0E00890
gene id: 1071381:TPHA_0E00890
uniprot id: G8BTF6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071381:TPHA 0C02060
gene id: 1071381:TPHA_0C02060
uniprot id: G8BRI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0A02620
gene id: 1071381:TPHA_0A02620
uniprot id: G8BN66
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1071381:TPHA 0G01430
gene id: 1071381:TPHA_0G01430
uniprot id: G8BVQ2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C03080
gene id: 1071381:TPHA_0C03080
uniprot id: G8BRT5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

1071381:TPHA 0G03260
gene id: 1071381:TPHA_0G03260
uniprot id: G8BW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

1071381:TPHA 0M01690
gene id: 1071381:TPHA_0M01690
uniprot id: G8C0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

1071381:TPHA 0K01430
gene id: 1071381:TPHA_0K01430
uniprot id: G8BZE8
names: Similarity
messages: Belongs to the cytidylyltransferase family.

1071381:TPHA 0A03840
gene id: 1071381:TPHA_0A03840
uniprot id: G8BNI2
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1071381:TPHA 0P00350
gene id: 1071381:TPHA_0P00350
uniprot id: G8C215
names: Similarity
messages: Belongs to the BLM10 family.

1071381:TPHA 0N00550
gene id: 1071381:TPHA_0N00550
uniprot id: G8C108
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071381:TPHA 0I01420
gene id: 1071381:TPHA_0I01420
uniprot id: G8BXM0
names: Similarity
messages: Belongs to the LSM12 family.

1071381:TPHA 0B04380
gene id: 1071381:TPHA_0B04380
uniprot id: G8BQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

1071381:TPHA 0B00480
gene id: 1071381:TPHA_0B00480
uniprot id: G8BQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

1071381:TPHA 0H00210
gene id: 1071381:TPHA_0H00210
uniprot id: G8BWS8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1071381:TPHA 0D01190
gene id: 1071381:TPHA_0D01190
uniprot id: G8BSD9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

1071381:TPHA 0C02410
gene id: 1071381:TPHA_0C02410
uniprot id: G8BRL8
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

1071381:TPHA 0C04270
gene id: 1071381:TPHA_0C04270
uniprot id: G8BQR5
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

1071381:TPHA 0E03340
gene id: 1071381:TPHA_0E03340
uniprot id: G8BU46
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1071381:TPHA 0A00920
gene id: 1071381:TPHA_0A00920
uniprot id: G8BMP9
names: Similarity
messages: Belongs to the actin family.

1071381:TPHA 0A03940
gene id: 1071381:TPHA_0A03940
uniprot id: G8BNJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus membrane

1071381:TPHA 0J01670
gene id: 1071381:TPHA_0J01670
uniprot id: G8BYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

1071381:TPHA 0D00180
gene id: 1071381:TPHA_0D00180
uniprot id: G8BS41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

1071381:TPHA 0G01190
gene id: 1071381:TPHA_0G01190
uniprot id: G8BVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1071381:TPHA 0J00320
gene id: 1071381:TPHA_0J00320
uniprot id: G8BYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0B03870
gene id: 1071381:TPHA_0B03870
uniprot id: G8BPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1071381:TPHA 0D00600
gene id: 1071381:TPHA_0D00600
uniprot id: G8BS83
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0G01900
gene id: 1071381:TPHA_0G01900
uniprot id: G8BVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

1071381:TPHA 0I01030
gene id: 1071381:TPHA_0I01030
uniprot id: G8BXI1
names: Similarity
messages: Belongs to the actin family.

1071381:TPHA 0B02400
gene id: 1071381:TPHA_0B02400
uniprot id: G8BPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

1071381:TPHA 0B01450
gene id: 1071381:TPHA_0B01450
uniprot id: G8BP87
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

1071381:TPHA 0A00760
gene id: 1071381:TPHA_0A00760
uniprot id: G8BMN3
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

1071381:TPHA 0G03430
gene id: 1071381:TPHA_0G03430
uniprot id: G8BWA5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0N01480
gene id: 1071381:TPHA_0N01480
uniprot id: G8C1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1071381:TPHA 0N00280
gene id: 1071381:TPHA_0N00280
uniprot id: G8C0Y1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0I02310
gene id: 1071381:TPHA_0I02310
uniprot id: G8BXV7
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071381:TPHA 0A04940
gene id: 1071381:TPHA_0A04940
uniprot id: G8BNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

1071381:TPHA 0I01880
gene id: 1071381:TPHA_0I01880
uniprot id: G8BXR4
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

1071381:TPHA 0B02800
gene id: 1071381:TPHA_0B02800
uniprot id: G8BPM1
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E01870
gene id: 1071381:TPHA_0E01870
uniprot id: G8BTQ2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0O00790
gene id: 1071381:TPHA_0O00790
uniprot id: G8C1M0
names: Similarity
messages: Belongs to the small Tim family.

1071381:TPHA 0D03230
gene id: 1071381:TPHA_0D03230
uniprot id: G8BSY8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

1071381:TPHA 0I01150
gene id: 1071381:TPHA_0I01150
uniprot id: G8BXJ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1071381:TPHA 0L02140
gene id: 1071381:TPHA_0L02140
uniprot id: G8C087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0K00800
gene id: 1071381:TPHA_0K00800
uniprot id: G8BZ86
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

1071381:TPHA 0N00470
gene id: 1071381:TPHA_0N00470
uniprot id: G8C0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071381:TPHA 0E02880
gene id: 1071381:TPHA_0E02880
uniprot id: G8BU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

1071381:TPHA 0B04730
gene id: 1071381:TPHA_0B04730
uniprot id: G8BQ61
names: Similarity
messages: Belongs to the multicopper oxidase family.

1071381:TPHA 0H00650
gene id: 1071381:TPHA_0H00650
uniprot id: G8BWX1
names: Similarity
messages: Belongs to the TrpF family.

1071381:TPHA 0L00770
gene id: 1071381:TPHA_0L00770
uniprot id: G8BZV5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

1071381:TPHA 0A02340
gene id: 1071381:TPHA_0A02340
uniprot id: G8BN38
names: Similarity
messages: Belongs to the PP2C family.

1071381:TPHA 0O01240
gene id: 1071381:TPHA_0O01240
uniprot id: G8C1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

1071381:TPHA 0E01340
gene id: 1071381:TPHA_0E01340
uniprot id: G8BTK1
names: Similarity
messages: Belongs to the ATPase delta chain family.

1071381:TPHA 0G03010
gene id: 1071381:TPHA_0G03010
uniprot id: G8BW64
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of TPHA0G03010 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

1071381:TPHA 0H00500
gene id: 1071381:TPHA_0H00500
uniprot id: G8BWV6
names: Similarity
messages: Belongs to the CWC26 family.

1071381:TPHA 0A01010
gene id: 1071381:TPHA_0A01010
uniprot id: G8BMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

1071381:TPHA 0F01400
gene id: 1071381:TPHA_0F01400
uniprot id: G8BV42
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

1071381:TPHA 0B03350
gene id: 1071381:TPHA_0B03350
uniprot id: G8BPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

1071381:TPHA 0H02510
gene id: 1071381:TPHA_0H02510
uniprot id: G8BWK3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E03860
gene id: 1071381:TPHA_0E03860
uniprot id: G8BU97
names: Similarity
messages: Belongs to the RPAP1 family.

1071381:TPHA 0C04740
gene id: 1071381:TPHA_0C04740
uniprot id: G8BQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

1071381:TPHA 0F00240
gene id: 1071381:TPHA_0F00240
uniprot id: G8BUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

1071381:TPHA 0B01510
gene id: 1071381:TPHA_0B01510
uniprot id: G8BP93
names: Similarity
messages: Belongs to the MIX23 family.

1071381:TPHA 0D01080
gene id: 1071381:TPHA_0D01080
uniprot id: G8BSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

1071381:TPHA 0H00740
gene id: 1071381:TPHA_0H00740
uniprot id: G8BWY0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1071381:TPHA 0E03520
gene id: 1071381:TPHA_0E03520
uniprot id: G8BU64
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0M01730
gene id: 1071381:TPHA_0M01730
uniprot id: G8C0N3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0K00390
gene id: 1071381:TPHA_0K00390
uniprot id: G8BZ45
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

1071381:TPHA 0C03820
gene id: 1071381:TPHA_0C03820
uniprot id: G8BQM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

1071381:TPHA 0M01030
gene id: 1071381:TPHA_0M01030
uniprot id: G8C0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1071381:TPHA 0F00850
gene id: 1071381:TPHA_0F00850
uniprot id: G8BUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071381:TPHA 0A03530
gene id: 1071381:TPHA_0A03530
uniprot id: G8BNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071381:TPHA 0B03990
gene id: 1071381:TPHA_0B03990
uniprot id: G8BPZ0
names: Similarity
messages: Belongs to the PET191 family.

1071381:TPHA 0M00810
gene id: 1071381:TPHA_0M00810
uniprot id: G8C0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

1071381:TPHA 0B01420
gene id: 1071381:TPHA_0B01420
uniprot id: G8BP84
names: Similarity
messages: Belongs to the TIP41 family.

1071381:TPHA 0J00930
gene id: 1071381:TPHA_0J00930
uniprot id: G8BYH3
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

1071381:TPHA 0F02200
gene id: 1071381:TPHA_0F02200
uniprot id: G8BVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IBD2 family.
messages: spindle pole

1071381:TPHA 0C05020
gene id: 1071381:TPHA_0C05020
uniprot id: G8BQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1071381:TPHA 0D01860
gene id: 1071381:TPHA_0D01860
uniprot id: G8BSK4
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.

1071381:TPHA 0I01490
gene id: 1071381:TPHA_0I01490
uniprot id: G8BXM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

1071381:TPHA 0E03940
gene id: 1071381:TPHA_0E03940
uniprot id: G8BUA5
names: Similarity
messages: Belongs to the MT-A70-like family.

1071381:TPHA 0E00360
gene id: 1071381:TPHA_0E00360
uniprot id: G8BTA4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0H03110
gene id: 1071381:TPHA_0H03110
uniprot id: G8BWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0C01400
gene id: 1071381:TPHA_0C01400
uniprot id: G8BRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

1071381:TPHA 0J03060
gene id: 1071381:TPHA_0J03060
uniprot id: G8BY75
names: Similarity
messages: Belongs to the AFG1 ATPase family.

1071381:TPHA 0F03600
gene id: 1071381:TPHA_0F03600
uniprot id: G8BUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

1071381:TPHA 0E02190
gene id: 1071381:TPHA_0E02190
uniprot id: G8BTT3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1071381:TPHA 0A03500
gene id: 1071381:TPHA_0A03500
uniprot id: G8BNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

1071381:TPHA 0C02920
gene id: 1071381:TPHA_0C02920
uniprot id: G8BRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0D00310
gene id: 1071381:TPHA_0D00310
uniprot id: G8BS54
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1071381:TPHA 0F02420
gene id: 1071381:TPHA_0F02420
uniprot id: G8BUD7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D00920
gene id: 1071381:TPHA_0D00920
uniprot id: G8BSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

1071381:TPHA 0G00850
gene id: 1071381:TPHA_0G00850
uniprot id: G8BVJ3
names: Similarity
messages: Belongs to the peptidase C19 family.

1071381:TPHA 0G00260
gene id: 1071381:TPHA_0G00260
uniprot id: G8BVD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0F03250
gene id: 1071381:TPHA_0F03250
uniprot id: G8BUM0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

1071381:TPHA 0J03090
gene id: 1071381:TPHA_0J03090
uniprot id: G8BY78
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0E02120
gene id: 1071381:TPHA_0E02120
uniprot id: G8BTS6
names: Similarity
messages: Belongs to the IUNH family.

1071381:TPHA 0D00300
gene id: 1071381:TPHA_0D00300
uniprot id: G8BS53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071381:TPHA 0B04510
gene id: 1071381:TPHA_0B04510
uniprot id: G8BQ39
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D02540
gene id: 1071381:TPHA_0D02540
uniprot id: G8BSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

1071381:TPHA 0D02890
gene id: 1071381:TPHA_0D02890
uniprot id: G8BSV4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1071381:TPHA 0O00800
gene id: 1071381:TPHA_0O00800
uniprot id: G8C1M1
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A00380
gene id: 1071381:TPHA_0A00380
uniprot id: G8BMJ5
names: Similarity
messages: Belongs to the WD repeat RTC1 family.

1071381:TPHA 0H01820
gene id: 1071381:TPHA_0H01820
uniprot id: G8BX83
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

1071381:TPHA 0P01220
gene id: 1071381:TPHA_0P01220
uniprot id: G8C2A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

1071381:TPHA 0L01110
gene id: 1071381:TPHA_0L01110
uniprot id: G8BZZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0O00710
gene id: 1071381:TPHA_0O00710
uniprot id: G8C1L2
names: Similarity
messages: Belongs to the WD repeat LST8 family.

1071381:TPHA 0B03880
gene id: 1071381:TPHA_0B03880
uniprot id: G8BPX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

1071381:TPHA 0D03640
gene id: 1071381:TPHA_0D03640
uniprot id: G8BT28
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition.

1071381:TPHA 0D00520
gene id: 1071381:TPHA_0D00520
uniprot id: G8BS75
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1071381:TPHA 0F01900
gene id: 1071381:TPHA_0F01900
uniprot id: G8BV90
names: Similarity
messages: Belongs to the MIP18 family.

1071381:TPHA 0J01140
gene id: 1071381:TPHA_0J01140
uniprot id: G8BYJ4
names: Similarity
messages: Belongs to the COG4 family.

1071381:TPHA 0H02840
gene id: 1071381:TPHA_0H02840
uniprot id: G8BWN6
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1071381:TPHA 0B02280
gene id: 1071381:TPHA_0B02280
uniprot id: G8BPG9
names: Similarity
messages: Belongs to the VAC14 family.

1071381:TPHA 0D02770
gene id: 1071381:TPHA_0D02770
uniprot id: G8BSU2
names: Similarity
messages: Belongs to the dpy-30 family.

1071381:TPHA 0A05400
gene id: 1071381:TPHA_0A05400
uniprot id: G8BNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

1071381:TPHA 0A00360
gene id: 1071381:TPHA_0A00360
uniprot id: G8BMJ3
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

1071381:TPHA 0C01020
gene id: 1071381:TPHA_0C01020
uniprot id: G8BR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

1071381:TPHA 0L00890
gene id: 1071381:TPHA_0L00890
uniprot id: G8BZW8
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A04740
gene id: 1071381:TPHA_0A04740
uniprot id: G8BNS1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1071381:TPHA 0E01720
gene id: 1071381:TPHA_0E01720
uniprot id: G8BTN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1071381:TPHA 0H02850
gene id: 1071381:TPHA_0H02850
uniprot id: G8BWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

1071381:TPHA 0I01120
gene id: 1071381:TPHA_0I01120
uniprot id: G8BXJ0
names: Similarity
messages: Belongs to the peptidase M28 family.

1071381:TPHA 0J01360
gene id: 1071381:TPHA_0J01360
uniprot id: G8BYL6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1071381:TPHA 0E03710
gene id: 1071381:TPHA_0E03710
uniprot id: G8BU82
names: Similarity
messages: Belongs to the RRP7 family.

1071381:TPHA 0C02140
gene id: 1071381:TPHA_0C02140
uniprot id: G8BRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

1071381:TPHA 0D01880
gene id: 1071381:TPHA_0D01880
uniprot id: G8BSK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

1071381:TPHA 0E03420
gene id: 1071381:TPHA_0E03420
uniprot id: G8BU54
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

1071381:TPHA 0A02960
gene id: 1071381:TPHA_0A02960
uniprot id: G8BN98
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0A00130
gene id: 1071381:TPHA_0A00130
uniprot id: G8BMH0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0F02910
gene id: 1071381:TPHA_0F02910
uniprot id: G8BUI6
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

1071381:TPHA 0G02840
gene id: 1071381:TPHA_0G02840
uniprot id: G8BW44
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

1071381:TPHA 0D01530
gene id: 1071381:TPHA_0D01530
uniprot id: G8BSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

1071381:TPHA 0J02340
gene id: 1071381:TPHA_0J02340
uniprot id: G8BYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

1071381:TPHA 0F02810
gene id: 1071381:TPHA_0F02810
uniprot id: G8BUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

1071381:TPHA 0K01590
gene id: 1071381:TPHA_0K01590
uniprot id: G8BZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

1071381:TPHA 0E02430
gene id: 1071381:TPHA_0E02430
uniprot id: G8BTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0O01910
gene id: 1071381:TPHA_0O01910
uniprot id: G8C1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

1071381:TPHA 0D03960
gene id: 1071381:TPHA_0D03960
uniprot id: G8BT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

1071381:TPHA 0G01280
gene id: 1071381:TPHA_0G01280
uniprot id: G8BVN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

1071381:TPHA 0K02140
gene id: 1071381:TPHA_0K02140
uniprot id: G8BZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

1071381:TPHA 0A03870
gene id: 1071381:TPHA_0A03870
uniprot id: G8BNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0E03840
gene id: 1071381:TPHA_0E03840
uniprot id: G8BU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0F02390
gene id: 1071381:TPHA_0F02390
uniprot id: G8BUD4
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0B04440
gene id: 1071381:TPHA_0B04440
uniprot id: G8BQ32
names: Similarity
messages: Belongs to the IST1 family.

1071381:TPHA 0F00760
gene id: 1071381:TPHA_0F00760
uniprot id: G8BUY0
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D03150
gene id: 1071381:TPHA_0D03150
uniprot id: G8BSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

1071381:TPHA 0D04480
gene id: 1071381:TPHA_0D04480
uniprot id: G8BS07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0A04890
gene id: 1071381:TPHA_0A04890
uniprot id: G8BNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

1071381:TPHA 0D03970
gene id: 1071381:TPHA_0D03970
uniprot id: G8BT59
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1071381:TPHA 0F01090
gene id: 1071381:TPHA_0F01090
uniprot id: G8BV12
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0G02970
gene id: 1071381:TPHA_0G02970
uniprot id: G8BW60
names: Similarity
messages: Belongs to the p23/wos2 family.

1071381:TPHA 0B01640
gene id: 1071381:TPHA_0B01640
uniprot id: G8BPA7
names: Similarity
messages: Belongs to the hexokinase family.

1071381:TPHA 0B04150
gene id: 1071381:TPHA_0B04150
uniprot id: G8BQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

1071381:TPHA 0P00180
gene id: 1071381:TPHA_0P00180
uniprot id: G8C1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0D01090
gene id: 1071381:TPHA_0D01090
uniprot id: G8BSC9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

1071381:TPHA 0G03060
gene id: 1071381:TPHA_0G03060
uniprot id: G8BW69
names: Similarity
messages: Belongs to the PdxS/SNZ family.

1071381:TPHA 0I03000
gene id: 1071381:TPHA_0I03000
uniprot id: G8BY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

1071381:TPHA 0P00500
gene id: 1071381:TPHA_0P00500
uniprot id: G8C230
names: Similarity
messages: Belongs to the citrate synthase family.

1071381:TPHA 0N00110
gene id: 1071381:TPHA_0N00110
uniprot id: G8C0W5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0C01340
gene id: 1071381:TPHA_0C01340
uniprot id: G8BRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0J02730
gene id: 1071381:TPHA_0J02730
uniprot id: G8BZ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

1071381:TPHA 0E00150
gene id: 1071381:TPHA_0E00150
uniprot id: G8BT84
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1071381:TPHA 0M01910
gene id: 1071381:TPHA_0M01910
uniprot id: G8C0Q1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

1071381:TPHA 0F02120
gene id: 1071381:TPHA_0F02120
uniprot id: G8BVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1071381:TPHA 0P00510
gene id: 1071381:TPHA_0P00510
uniprot id: G8C231
names: Similarity
messages: Belongs to the LOC1 family.

1071381:TPHA 0D03985
gene id: 1071381:TPHA_0D03985
uniprot id: G8BT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1071381:TPHA 0J02720
gene id: 1071381:TPHA_0J02720
uniprot id: G8BZ00
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

1071381:TPHA 0H02040
gene id: 1071381:TPHA_0H02040
uniprot id: G8BWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

1071381:TPHA 0J02360
gene id: 1071381:TPHA_0J02360
uniprot id: G8BYW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

1071381:TPHA 0E01800
gene id: 1071381:TPHA_0E01800
uniprot id: G8BTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

1071381:TPHA 0G03470
gene id: 1071381:TPHA_0G03470
uniprot id: G8BWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0B04290
gene id: 1071381:TPHA_0B04290
uniprot id: G8BQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

1071381:TPHA 0A04730
gene id: 1071381:TPHA_0A04730
uniprot id: G8BNS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

1071381:TPHA 0F02280
gene id: 1071381:TPHA_0F02280
uniprot id: G8BUC3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

1071381:TPHA 0I02040
gene id: 1071381:TPHA_0I02040
uniprot id: G8BXT0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0E02480
gene id: 1071381:TPHA_0E02480
uniprot id: G8BTW2
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

1071381:TPHA 0M01230
gene id: 1071381:TPHA_0M01230
uniprot id: G8C0I3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0B01920
gene id: 1071381:TPHA_0B01920
uniprot id: G8BPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

1071381:TPHA 0G01760
gene id: 1071381:TPHA_0G01760
uniprot id: G8BVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

1071381:TPHA 0P00460
gene id: 1071381:TPHA_0P00460
uniprot id: G8C226
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0D01230
gene id: 1071381:TPHA_0D01230
uniprot id: G8BSE3
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

1071381:TPHA 0D04650
gene id: 1071381:TPHA_0D04650
uniprot id: G8BS24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1071381:TPHA 0B04450
gene id: 1071381:TPHA_0B04450
uniprot id: G8BQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

1071381:TPHA 0F02380
gene id: 1071381:TPHA_0F02380
uniprot id: G8BUD3
names: Similarity
messages: Belongs to the importin alpha family.

1071381:TPHA 0A04240
gene id: 1071381:TPHA_0A04240
uniprot id: G8BNM1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1071381:TPHA 0C02230
gene id: 1071381:TPHA_0C02230
uniprot id: G8BRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0I03050
gene id: 1071381:TPHA_0I03050
uniprot id: G8BY28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1071381:TPHA 0A03180
gene id: 1071381:TPHA_0A03180
uniprot id: G8BNB6
names: Similarity
messages: Belongs to the PPP phosphatase family.

1071381:TPHA 0B03650
gene id: 1071381:TPHA_0B03650
uniprot id: G8BPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

1071381:TPHA 0B00450
gene id: 1071381:TPHA_0B00450
uniprot id: G8BQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

1071381:TPHA 0J00590
gene id: 1071381:TPHA_0J00590
uniprot id: G8BYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

1071381:TPHA 0N00740
gene id: 1071381:TPHA_0N00740
uniprot id: G8C127
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071381:TPHA 0A05960
gene id: 1071381:TPHA_0A05960
uniprot id: G8BP42
names: Similarity
messages: Belongs to the SAPS family.

1071381:TPHA 0D00350
gene id: 1071381:TPHA_0D00350
uniprot id: G8BS58
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

1071381:TPHA 0G03130
gene id: 1071381:TPHA_0G03130
uniprot id: G8BW76
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

1071381:TPHA 0C04320
gene id: 1071381:TPHA_0C04320
uniprot id: G8BQS0
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

1071381:TPHA 0D03200
gene id: 1071381:TPHA_0D03200
uniprot id: G8BSY5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

1071381:TPHA 0K02010
gene id: 1071381:TPHA_0K02010
uniprot id: G8BZK6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

1071381:TPHA 0B03230
gene id: 1071381:TPHA_0B03230
uniprot id: G8BPR4
names: Similarity
messages: Belongs to the SUN family.

1071381:TPHA 0E03800
gene id: 1071381:TPHA_0E03800
uniprot id: G8BU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

1071381:TPHA 0D03850
gene id: 1071381:TPHA_0D03850
uniprot id: G8BT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

1071381:TPHA 0B02430
gene id: 1071381:TPHA_0B02430
uniprot id: G8BPI5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0D01510
gene id: 1071381:TPHA_0D01510
uniprot id: G8BSH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

1071381:TPHA 0F03510
gene id: 1071381:TPHA_0F03510
uniprot id: G8BUP5
names: Similarity
messages: Belongs to the thymidylate kinase family.

1071381:TPHA 0B01100
gene id: 1071381:TPHA_0B01100
uniprot id: G8BQI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

1071381:TPHA 0G02750
gene id: 1071381:TPHA_0G02750
uniprot id: G8BW35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1071381:TPHA 0J01910
gene id: 1071381:TPHA_0J01910
uniprot id: G8BYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

1071381:TPHA 0M01760
gene id: 1071381:TPHA_0M01760
uniprot id: G8C0N6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0E00960
gene id: 1071381:TPHA_0E00960
uniprot id: G8BTG2
names: Similarity
messages: Belongs to the RICTOR family.

1071381:TPHA 0J02060
gene id: 1071381:TPHA_0J02060
uniprot id: G8BYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

1071381:TPHA 0N01360
gene id: 1071381:TPHA_0N01360
uniprot id: G8C189
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1071381:TPHA 0K01620
gene id: 1071381:TPHA_0K01620
uniprot id: G8BZG7
names: Similarity
messages: Belongs to the HscB family.

1071381:TPHA 0F00460
gene id: 1071381:TPHA_0F00460
uniprot id: G8BUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0O01900
gene id: 1071381:TPHA_0O01900
uniprot id: G8C1X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1071381:TPHA 0L00180
gene id: 1071381:TPHA_0L00180
uniprot id: G8BZP7
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

1071381:TPHA 0A01830
gene id: 1071381:TPHA_0A01830
uniprot id: G8BMY8
names: Function
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

1071381:TPHA 0G03220
gene id: 1071381:TPHA_0G03220
uniprot id: G8BW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

1071381:TPHA 0M00720
gene id: 1071381:TPHA_0M00720
uniprot id: G8C0D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1071381:TPHA 0G03320
gene id: 1071381:TPHA_0G03320
uniprot id: G8BW94
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0I00280
gene id: 1071381:TPHA_0I00280
uniprot id: G8BXA7
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

1071381:TPHA 0C01730
gene id: 1071381:TPHA_0C01730
uniprot id: G8BRF3
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

1071381:TPHA 0I00900
gene id: 1071381:TPHA_0I00900
uniprot id: G8BXG8
names: Similarity
messages: Belongs to the SAPS family.

1071381:TPHA 0E02470
gene id: 1071381:TPHA_0E02470
uniprot id: G8BTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0B02620
gene id: 1071381:TPHA_0B02620
uniprot id: G8BPK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1071381:TPHA 0N00630
gene id: 1071381:TPHA_0N00630
uniprot id: G8C116
names: Similarity
messages: Belongs to the HGH1 family.

1071381:TPHA 0L01830
gene id: 1071381:TPHA_0L01830
uniprot id: G8C058
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

1071381:TPHA 0I03280
gene id: 1071381:TPHA_0I03280
uniprot id: G8BY51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

1071381:TPHA 0M00760
gene id: 1071381:TPHA_0M00760
uniprot id: G8C0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

1071381:TPHA 0N00490
gene id: 1071381:TPHA_0N00490
uniprot id: G8C101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

1071381:TPHA 0J01570
gene id: 1071381:TPHA_0J01570
uniprot id: G8BYN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

1071381:TPHA 0I01480
gene id: 1071381:TPHA_0I01480
uniprot id: G8BXM6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

1071381:TPHA 0C01180
gene id: 1071381:TPHA_0C01180
uniprot id: G8BR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F03620
gene id: 1071381:TPHA_0F03620
uniprot id: G8BUQ6
names: Similarity
messages: Belongs to the MOG1 family.

1071381:TPHA 0E00840
gene id: 1071381:TPHA_0E00840
uniprot id: G8BTF1
names: Similarity
messages: Belongs to the AAR2 family.

1071381:TPHA 0B00510
gene id: 1071381:TPHA_0B00510
uniprot id: G8BQC6
names: Similarity
messages: Belongs to the type-1 OGG1 family.

1071381:TPHA 0D02330
gene id: 1071381:TPHA_0D02330
uniprot id: G8BSP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

1071381:TPHA 0I00650
gene id: 1071381:TPHA_0I00650
uniprot id: G8BXE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

1071381:TPHA 0A01630
gene id: 1071381:TPHA_0A01630
uniprot id: G8BMW8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

1071381:TPHA 0H02720
gene id: 1071381:TPHA_0H02720
uniprot id: G8BWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071381:TPHA 0N00310
gene id: 1071381:TPHA_0N00310
uniprot id: G8C0Y4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1071381:TPHA 0A01890
gene id: 1071381:TPHA_0A01890
uniprot id: G8BMZ4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1071381:TPHA 0L01480
gene id: 1071381:TPHA_0L01480
uniprot id: G8C025
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

1071381:TPHA 0D01470
gene id: 1071381:TPHA_0D01470
uniprot id: G8BSG6
names: Similarity
messages: Belongs to the AAA ATPase family.

1071381:TPHA 0H02650
gene id: 1071381:TPHA_0H02650
uniprot id: G8BWL7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

1071381:TPHA 0A04480
gene id: 1071381:TPHA_0A04480
uniprot id: G8BNP3
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

1071381:TPHA 0I01450
gene id: 1071381:TPHA_0I01450
uniprot id: G8BXM3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A05970
gene id: 1071381:TPHA_0A05970
uniprot id: G8BP43
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

1071381:TPHA 0I01870
gene id: 1071381:TPHA_0I01870
uniprot id: G8BXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

1071381:TPHA 0A04470
gene id: 1071381:TPHA_0A04470
uniprot id: G8BNP2
names: Similarity
messages: Belongs to the UPP synthase family.

1071381:TPHA 0E03220
gene id: 1071381:TPHA_0E03220
uniprot id: G8BU34
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1071381:TPHA 0O00260
gene id: 1071381:TPHA_0O00260
uniprot id: G8C1H0
names: Similarity
messages: Belongs to the WrbA family.

1071381:TPHA 0P01500
gene id: 1071381:TPHA_0P01500
uniprot id: G8C2D0
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00560
gene id: 1071381:TPHA_0L00560
uniprot id: G8BZT4
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0G00910
gene id: 1071381:TPHA_0G00910
uniprot id: G8BVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0C00200
gene id: 1071381:TPHA_0C00200
uniprot id: G8BR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

1071381:TPHA 0B01310
gene id: 1071381:TPHA_0B01310
uniprot id: G8BP73
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1071381:TPHA 0F03670
gene id: 1071381:TPHA_0F03670
uniprot id: G8BUR1
names: Similarity
messages: Belongs to the oxoprolinase family.

1071381:TPHA 0N00170
gene id: 1071381:TPHA_0N00170
uniprot id: G8C0X0
names: Similarity
messages: Belongs to the calreticulin family.

1071381:TPHA 0G01000
gene id: 1071381:TPHA_0G01000
uniprot id: G8BVK8
names: Similarity
messages: Belongs to the SAP30 family.

1071381:TPHA 0O01550
gene id: 1071381:TPHA_0O01550
uniprot id: G8C1U4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

1071381:TPHA 0A05050
gene id: 1071381:TPHA_0A05050
uniprot id: G8BNV2
names: Subcellular Location Annotation
messages: Peroxisome membrane

1071381:TPHA 0P00930
gene id: 1071381:TPHA_0P00930
uniprot id: G8C273
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

1071381:TPHA 0A03520
gene id: 1071381:TPHA_0A03520
uniprot id: G8BNF0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

1071381:TPHA 0G00890
gene id: 1071381:TPHA_0G00890
uniprot id: G8BVJ7
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

1071381:TPHA 0A05070
gene id: 1071381:TPHA_0A05070
uniprot id: G8BNV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1071381:TPHA 0N01930
gene id: 1071381:TPHA_0N01930
uniprot id: G8C1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1071381:TPHA 0P00580
gene id: 1071381:TPHA_0P00580
uniprot id: G8C238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

1071381:TPHA 0J01680
gene id: 1071381:TPHA_0J01680
uniprot id: G8BYP7
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D03760
gene id: 1071381:TPHA_0D03760
uniprot id: G8BT38
names: Similarity
messages: Belongs to the peptidase S8 family.

1071381:TPHA 0I00640
gene id: 1071381:TPHA_0I00640
uniprot id: G8BXE2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

1071381:TPHA 0I00130
gene id: 1071381:TPHA_0I00130
uniprot id: G8BX92
names: Subcellular Location Annotation
messages: nucleolus

1071381:TPHA 0B00490
gene id: 1071381:TPHA_0B00490
uniprot id: G8BQC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

1071381:TPHA 0P00990
gene id: 1071381:TPHA_0P00990
uniprot id: G8C279
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

1071381:TPHA 0C03480
gene id: 1071381:TPHA_0C03480
uniprot id: G8BVI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

1071381:TPHA 0M00620
gene id: 1071381:TPHA_0M00620
uniprot id: G8C0C2
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D00690
gene id: 1071381:TPHA_0D00690
uniprot id: G8BS91
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C01570
gene id: 1071381:TPHA_0C01570
uniprot id: G8BRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

1071381:TPHA 0D02450
gene id: 1071381:TPHA_0D02450
uniprot id: G8BSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0I01440
gene id: 1071381:TPHA_0I01440
uniprot id: G8BXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

1071381:TPHA 0D04510
gene id: 1071381:TPHA_0D04510
uniprot id: G8BS10
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

1071381:TPHA 0C02930
gene id: 1071381:TPHA_0C02930
uniprot id: G8BRS0
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

1071381:TPHA 0C04420
gene id: 1071381:TPHA_0C04420
uniprot id: G8BQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
messages: Nucleus

1071381:TPHA 0N00720
gene id: 1071381:TPHA_0N00720
uniprot id: G8C125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

1071381:TPHA 0C02620
gene id: 1071381:TPHA_0C02620
uniprot id: G8BRN9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0L00950
gene id: 1071381:TPHA_0L00950
uniprot id: G8BZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

1071381:TPHA 0C02900
gene id: 1071381:TPHA_0C02900
uniprot id: G8BRR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

1071381:TPHA 0A04430
gene id: 1071381:TPHA_0A04430
uniprot id: G8BNN8
names: Similarity
messages: Belongs to the TCP11 family.

1071381:TPHA 0K01840
gene id: 1071381:TPHA_0K01840
uniprot id: G8BZI8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1071381:TPHA 0G01810
gene id: 1071381:TPHA_0G01810
uniprot id: G8BVT9
names: Similarity
messages: Belongs to the peptidase S9B family.

1071381:TPHA 0D02100
gene id: 1071381:TPHA_0D02100
uniprot id: G8BSM7
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

1071381:TPHA 0K00430
gene id: 1071381:TPHA_0K00430
uniprot id: G8BZ49
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

1071381:TPHA 0K01250
gene id: 1071381:TPHA_0K01250
uniprot id: G8BZD1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

1071381:TPHA 0I01010
gene id: 1071381:TPHA_0I01010
uniprot id: G8BXH9
names: Similarity
messages: Belongs to the IML2 family.

1071381:TPHA 0E03610
gene id: 1071381:TPHA_0E03610
uniprot id: G8BUB6
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0I00400
gene id: 1071381:TPHA_0I00400
uniprot id: G8BXB9
names: Similarity
messages: Belongs to the sorting nexin family.

1071381:TPHA 0C02200
gene id: 1071381:TPHA_0C02200
uniprot id: G8BRJ8
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

1071381:TPHA 0I03230
gene id: 1071381:TPHA_0I03230
uniprot id: G8BY46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

1071381:TPHA 0B03840
gene id: 1071381:TPHA_0B03840
uniprot id: G8BPX5
names: Similarity
messages: Belongs to the citrate synthase family.

1071381:TPHA 0I02680
gene id: 1071381:TPHA_0I02680
uniprot id: G8BXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

1071381:TPHA 0L01740
gene id: 1071381:TPHA_0L01740
uniprot id: G8C049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0O01770
gene id: 1071381:TPHA_0O01770
uniprot id: G8C1W6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1071381:TPHA 0F02850
gene id: 1071381:TPHA_0F02850
uniprot id: G8BUI0
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

1071381:TPHA 0K00670
gene id: 1071381:TPHA_0K00670
uniprot id: G8BZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

1071381:TPHA 0P01150
gene id: 1071381:TPHA_0P01150
uniprot id: G8C295
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D01420
gene id: 1071381:TPHA_0D01420
uniprot id: G8BSG2
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

1071381:TPHA 0N01030
gene id: 1071381:TPHA_0N01030
uniprot id: G8C156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0B02130
gene id: 1071381:TPHA_0B02130
uniprot id: G8BPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

1071381:TPHA 0B04280
gene id: 1071381:TPHA_0B04280
uniprot id: G8BQ16
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.

1071381:TPHA 0G03780
gene id: 1071381:TPHA_0G03780
uniprot id: G8BWD9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

1071381:TPHA 0A01390
gene id: 1071381:TPHA_0A01390
uniprot id: G8BMU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

1071381:TPHA 0O00990
gene id: 1071381:TPHA_0O00990
uniprot id: G8C1P0
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

1071381:TPHA 0G01700
gene id: 1071381:TPHA_0G01700
uniprot id: G8BVS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1071381:TPHA 0P00470
gene id: 1071381:TPHA_0P00470
uniprot id: G8C227
names: Similarity
messages: Belongs to the peptidase M67A family.

1071381:TPHA 0G03150
gene id: 1071381:TPHA_0G03150
uniprot id: G8BW77
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A00940
gene id: 1071381:TPHA_0A00940
uniprot id: G8BMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

1071381:TPHA 0D01280
gene id: 1071381:TPHA_0D01280
uniprot id: G8BSE8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

1071381:TPHA 0N01610
gene id: 1071381:TPHA_0N01610
uniprot id: G8C1B4
names: Similarity
messages: Belongs to the SEN15 family.

1071381:TPHA 0M01420
gene id: 1071381:TPHA_0M01420
uniprot id: G8C0K2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

1071381:TPHA 0K02160
gene id: 1071381:TPHA_0K02160
uniprot id: G8BZL9
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0P01480
gene id: 1071381:TPHA_0P01480
uniprot id: G8C2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0O01360
gene id: 1071381:TPHA_0O01360
uniprot id: G8C1S6
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

1071381:TPHA 0J02540
gene id: 1071381:TPHA_0J02540
uniprot id: G8BYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

1071381:TPHA 0H01750
gene id: 1071381:TPHA_0H01750
uniprot id: G8BX77
names: Similarity
messages: Belongs to the peptidase M18 family.

1071381:TPHA 0A04880
gene id: 1071381:TPHA_0A04880
uniprot id: G8BNT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

1071381:TPHA 0P00630
gene id: 1071381:TPHA_0P00630
uniprot id: G8C243
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A02050
gene id: 1071381:TPHA_0A02050
uniprot id: G8BN09
names: Similarity
messages: Belongs to the COG3 family.

1071381:TPHA 0G02700
gene id: 1071381:TPHA_0G02700
uniprot id: G8BW29
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0L01490
gene id: 1071381:TPHA_0L01490
uniprot id: G8C026
names: Similarity
messages: Belongs to the PGA52 family.

1071381:TPHA 0B00970
gene id: 1071381:TPHA_0B00970
uniprot id: G8BQH2
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

1071381:TPHA 0L01500
gene id: 1071381:TPHA_0L01500
uniprot id: G8C027
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E03530
gene id: 1071381:TPHA_0E03530
uniprot id: G8BU65
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

1071381:TPHA 0E02390
gene id: 1071381:TPHA_0E02390
uniprot id: G8BTV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

1071381:TPHA 0M01930
gene id: 1071381:TPHA_0M01930
uniprot id: G8C0Q3
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

1071381:TPHA 0A04750
gene id: 1071381:TPHA_0A04750
uniprot id: G8BNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1071381:TPHA 0A01030
gene id: 1071381:TPHA_0A01030
uniprot id: G8BMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

1071381:TPHA 0B02520
gene id: 1071381:TPHA_0B02520
uniprot id: G8BPJ4
names: Similarity
messages: Belongs to the lariat debranching enzyme family.

1071381:TPHA 0G02920
gene id: 1071381:TPHA_0G02920
uniprot id: G8BW55
names: Similarity
messages: Belongs to the RRN3 family.

1071381:TPHA 0E03560
gene id: 1071381:TPHA_0E03560
uniprot id: G8BU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

1071381:TPHA 0J02170
gene id: 1071381:TPHA_0J02170
uniprot id: G8BYU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1071381:TPHA 0C04150
gene id: 1071381:TPHA_0C04150
uniprot id: G8BQQ3
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0D03910
gene id: 1071381:TPHA_0D03910
uniprot id: G8BT53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

1071381:TPHA 0F00390
gene id: 1071381:TPHA_0F00390
uniprot id: G8BUU4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

1071381:TPHA 0H02660
gene id: 1071381:TPHA_0H02660
uniprot id: G8BWL8
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0A00570
gene id: 1071381:TPHA_0A00570
uniprot id: G8BML4
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

1071381:TPHA 0I00180
gene id: 1071381:TPHA_0I00180
uniprot id: G8BX97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

1071381:TPHA 0G01870
gene id: 1071381:TPHA_0G01870
uniprot id: G8BVU5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

1071381:TPHA 0F00880
gene id: 1071381:TPHA_0F00880
uniprot id: G8BUZ2
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

1071381:TPHA 0C01720
gene id: 1071381:TPHA_0C01720
uniprot id: G8BRF2
names: Similarity
messages: Belongs to the SKP1 family.

1071381:TPHA 0B02200
gene id: 1071381:TPHA_0B02200
uniprot id: G8BPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

1071381:TPHA 0F01080
gene id: 1071381:TPHA_0F01080
uniprot id: G8BV11
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

1071381:TPHA 0G02060
gene id: 1071381:TPHA_0G02060
uniprot id: G8BVW4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1071381:TPHA 0A04680
gene id: 1071381:TPHA_0A04680
uniprot id: G8BNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

1071381:TPHA 0G01550
gene id: 1071381:TPHA_0G01550
uniprot id: G8BVR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1071381:TPHA 0H00770
gene id: 1071381:TPHA_0H00770
uniprot id: G8BWY3
names: Similarity
messages: Belongs to the OSBP family.

1071381:TPHA 0M00600
gene id: 1071381:TPHA_0M00600
uniprot id: G8C0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

1071381:TPHA 0L00880
gene id: 1071381:TPHA_0L00880
uniprot id: G8BZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

1071381:TPHA 0J00840
gene id: 1071381:TPHA_0J00840
uniprot id: G8BYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1071381:TPHA 0A05000
gene id: 1071381:TPHA_0A05000
uniprot id: G8BNU7
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

1071381:TPHA 0A02320
gene id: 1071381:TPHA_0A02320
uniprot id: G8BN36
names: Similarity
messages: Belongs to the RNR ribonuclease family.

1071381:TPHA 0A05600
gene id: 1071381:TPHA_0A05600
uniprot id: G8BP06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

1071381:TPHA 0I03320
gene id: 1071381:TPHA_0I03320
uniprot id: G8BY56
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0N01160
gene id: 1071381:TPHA_0N01160
uniprot id: G8C169
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSA1 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

1071381:TPHA 0P01770
gene id: 1071381:TPHA_0P01770
uniprot id: G8C2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

1071381:TPHA 0D02510
gene id: 1071381:TPHA_0D02510
uniprot id: G8BSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

1071381:TPHA 0M01380
gene id: 1071381:TPHA_0M01380
uniprot id: G8C0J8
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

1071381:TPHA 0E04090
gene id: 1071381:TPHA_0E04090
uniprot id: G8BUB8
names: Subcellular Location Annotation
messages: Cytoplasm

1071381:TPHA 0A01530
gene id: 1071381:TPHA_0A01530
uniprot id: G8BMV8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1071381:TPHA 0G02630
gene id: 1071381:TPHA_0G02630
uniprot id: G8BW22
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0N01800
gene id: 1071381:TPHA_0N01800
uniprot id: G8C1D3
names: Subcellular Location Annotation
messages: Nucleus

1071381:TPHA 0C04600
gene id: 1071381:TPHA_0C04600
uniprot id: G8BQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

1071381:TPHA 0D02700
gene id: 1071381:TPHA_0D02700
uniprot id: G8BST5
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0A04703
gene id: 1071381:TPHA_0A04703
uniprot id: G8BNR6
names: Subcellular Location Annotation
messages: Membrane

1071381:TPHA 0E01090
gene id: 1071381:TPHA_0E01090
uniprot id: G8BTH5
names: Similarity
messages: Belongs to the OSBP family.

1071381:TPHA 0G02950
gene id: 1071381:TPHA_0G02950
uniprot id: G8BW58
names: Similarity
messages: Belongs to the UPP synthase family.

1071381:TPHA 0B02450
gene id: 1071381:TPHA_0B02450
uniprot id: G8BPI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

1071381:TPHA 0B02050
gene id: 1071381:TPHA_0B02050
uniprot id: G8BPE6
names: Similarity
messages: Belongs to the SRR1 family.