106582:LOC101483142
gene id: 106582:LOC101483142
uniprot id: A0A3P9C3L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

106582:LOC101471957
gene id: 106582:LOC101471957
uniprot id: A0A3P9D7I3
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

106582:psma3
gene id: 106582:psma3
uniprot id: A0A3P9CLS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:lin28b
gene id: 106582:lin28b
uniprot id: A0A3P9CR76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

106582:LOC101469091
gene id: 106582:LOC101469091
uniprot id: A0A3P9D5N7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

106582:LOC101467048
gene id: 106582:LOC101467048
uniprot id: A0A3P9AWF1
names: Similarity
messages: Belongs to the intermediate filament family.

106582:lasp1
gene id: 106582:lasp1
uniprot id: A0A3P9D7Y1
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

106582:ppp4r3a
gene id: 106582:ppp4r3a
uniprot id: A0A3P9CR34
names: Similarity
messages: Belongs to the SMEK family.

106582:cacnb2
gene id: 106582:cacnb2
uniprot id: A0A3P9AU67
uniprot id: A0A3P9AUA2
names: Function
names: Similarity
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

106582:fam167a
gene id: 106582:fam167a
uniprot id: A0A3P9CH27
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

106582:ltbp3
gene id: 106582:ltbp3
uniprot id: A0A3P9CJ58
uniprot id: A0A3P9CKK4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:uckl1
gene id: 106582:uckl1
uniprot id: A0A3P9DB49
uniprot id: A0A3P9DBU2
uniprot id: A0A3P9DBV4
names: Similarity
messages: Belongs to the uridine kinase family.

106582:LOC101473551
gene id: 106582:LOC101473551
uniprot id: A0A3P9DQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

106582:pgm2l1
gene id: 106582:pgm2l1
uniprot id: A0A3P9AWN6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

106582:LOC101474681
gene id: 106582:LOC101474681
uniprot id: A0A3P9CCK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:nt5c3a
gene id: 106582:nt5c3a
uniprot id: A0A3P9BT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

106582:LOC101469078
gene id: 106582:LOC101469078
uniprot id: A0A3P9B5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC43A transporter (TC 2.A.1.44) family.
messages: Membrane

106582:LOC101480091
gene id: 106582:LOC101480091
uniprot id: A0A3P9D203
names: Similarity
messages: Belongs to the ubiquitin family.

106582:LOC101475990
gene id: 106582:LOC101475990
uniprot id: A0A3P9AYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

106582:prkacb
gene id: 106582:prkacb
uniprot id: A0A3P9DJD7
uniprot id: A0A3P9DJY8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

106582:mrps10
gene id: 106582:mrps10
uniprot id: A0A3P9CPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

106582:LOC101483499
gene id: 106582:LOC101483499
uniprot id: A0A3P9C7M7
names: Similarity
messages: Belongs to the nucleoplasmin family.

106582:LOC101485380
gene id: 106582:LOC101485380
uniprot id: A0A3P9C476
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:pdik1l
gene id: 106582:pdik1l
uniprot id: A0A3P9CLI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:cd74
gene id: 106582:cd74
uniprot id: A0A3P9C507
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:thumpd3
gene id: 106582:thumpd3
uniprot id: A0A3P9BWR8
names: Similarity
messages: Belongs to the methyltransferase superfamily.

106582:LOC101469798
gene id: 106582:LOC101469798
uniprot id: A0A3P9C343
names: Subcellular Location Annotation
messages: cytosol

106582:amacr
gene id: 106582:amacr
uniprot id: A0A3P9ARU3
names: Similarity
messages: Belongs to the CoA-transferase III family.

106582:LOC101473108
gene id: 106582:LOC101473108
uniprot id: A0A3P9CB35
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101465653
gene id: 106582:LOC101465653
uniprot id: A0A3P9DQF3
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

106582:tdo2
gene id: 106582:tdo2
uniprot id: A0A3P9AVR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:u2af2
gene id: 106582:u2af2
uniprot id: A0A3P9CJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

106582:LOC101466186
gene id: 106582:LOC101466186
uniprot id: A0A3P9BC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

106582:map4k3
gene id: 106582:map4k3
uniprot id: A0A3P9DQX9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

106582:slc17a6
gene id: 106582:slc17a6
uniprot id: A0A3P9AZ39
names: Subcellular Location Annotation
messages: Membrane

106582:smarcd1
gene id: 106582:smarcd1
uniprot id: A0A3P9B6Q0
names: Similarity
messages: Belongs to the SMARCD family.

106582:LOC101477849
gene id: 106582:LOC101477849
uniprot id: A0A3P9DAF8
names: Subcellular Location Annotation
messages: Nucleus

106582:spsb3
gene id: 106582:spsb3
uniprot id: A0A3P9BR14
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

106582:LOC101478757
gene id: 106582:LOC101478757
uniprot id: A0A3P9CB73
names: Subcellular Location Annotation
messages: Nucleus

106582:ebp
gene id: 106582:ebp
uniprot id: A0A3P9DPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101487029
gene id: 106582:LOC101487029
uniprot id: A0A3P9BPA9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

106582:LOC101465588
gene id: 106582:LOC101465588
uniprot id: A0A3P9AXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

106582:nudt12
gene id: 106582:nudt12
uniprot id: A0A3P9CX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

106582:LOC101485425
gene id: 106582:LOC101485425
uniprot id: A0A3P9CAT0
names: Subcellular Location Annotation
messages: Membrane

106582:pacs2
gene id: 106582:pacs2
uniprot id: A0A3P9BVV4
names: Similarity
messages: Belongs to the PACS family.

106582:wasf1
gene id: 106582:wasf1
uniprot id: A0A3P9CLT2
uniprot id: A0A3P9CNA7
uniprot id: A0A3P9CNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

106582:LOC101483363
gene id: 106582:LOC101483363
uniprot id: A0A3P9D1T9
names: Similarity
messages: Belongs to the thioredoxin family.

106582:LOC101466476
gene id: 106582:LOC101466476
uniprot id: A0A3P9BJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:psmb3
gene id: 106582:psmb3
uniprot id: A0A3P9C375
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

106582:cbl
gene id: 106582:cbl
uniprot id: A0A3P9CEW1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

106582:zranb2
gene id: 106582:zranb2
uniprot id: A0A3P9CPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

106582:LOC101482449
gene id: 106582:LOC101482449
uniprot id: A0A3P9D0Z0
names: Similarity
messages: Belongs to the FBPase class 1 family.

106582:tnk2
gene id: 106582:tnk2
uniprot id: A0A3P9BMW7
uniprot id: A0A3P9BN09
uniprot id: A0A3P9BN36
uniprot id: A0A3P9BNS6
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

106582:LOC101469848
gene id: 106582:LOC101469848
uniprot id: A0A3P9C634
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473655
gene id: 106582:LOC101473655
uniprot id: A0A3P9BES3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

106582:wdpcp
gene id: 106582:wdpcp
uniprot id: A0A3P9DPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

106582:b3gat2
gene id: 106582:b3gat2
uniprot id: A0A3P9CQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:sncb
gene id: 106582:sncb
uniprot id: A0A3P9BQP9
names: Similarity
messages: Belongs to the synuclein family.

106582:exoc7
gene id: 106582:exoc7
uniprot id: A0A3P9BRP9
uniprot id: A0A3P9BRQ2
uniprot id: A0A3P9BRY0
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

106582:dgkq
gene id: 106582:dgkq
uniprot id: A0A3P9B5E0
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

106582:fam20a
gene id: 106582:fam20a
uniprot id: A0A3P9BQZ5
names: Similarity
messages: Belongs to the FAM20 family.

106582:rab4a
gene id: 106582:rab4a
uniprot id: A0A3P9BXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

106582:lg4h11orf88
gene id: 106582:lg4h11orf88
uniprot id: A0A3P9B0P6
names: Similarity
messages: Belongs to the HOATZ family.

106582:LOC101469049
gene id: 106582:LOC101469049
uniprot id: A0A3P9DLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

106582:LOC101468360
gene id: 106582:LOC101468360
uniprot id: A0A3P9AYF4
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

106582:LOC101466550
gene id: 106582:LOC101466550
uniprot id: A0A3P9B0P0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:LOC101479120
gene id: 106582:LOC101479120
uniprot id: A0A3P9CT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

106582:nrn1
gene id: 106582:nrn1
uniprot id: A0A3P9CZA2
names: Similarity
messages: Belongs to the neuritin family.

106582:LOC101479845
gene id: 106582:LOC101479845
uniprot id: A0A3P9BUT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:kif11
gene id: 106582:kif11
uniprot id: A0A3P9B1I3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:nid1
gene id: 106582:nid1
uniprot id: A0A3P9BUG9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

106582:dcp2
gene id: 106582:dcp2
uniprot id: A0A3P9BR84
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

106582:LOC101482175
gene id: 106582:LOC101482175
uniprot id: A0A3P9BKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

106582:hbs1l
gene id: 106582:hbs1l
uniprot id: A0A3P9CFG1
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Interacts with the SKI complex.

106582:LOC101487154
gene id: 106582:LOC101487154
uniprot id: A0A3P9BLQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101480509
gene id: 106582:LOC101480509
uniprot id: A0A3P9C590
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

106582:LOC101469934
gene id: 106582:LOC101469934
uniprot id: A0A3P9AZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:synm
gene id: 106582:synm
uniprot id: A0A3P9D2V7
names: Similarity
messages: Belongs to the intermediate filament family.

106582:ildr2
gene id: 106582:ildr2
uniprot id: A0A3P9D4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

106582:atp11b
gene id: 106582:atp11b
uniprot id: A0A3P9CFV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

106582:plppr1
gene id: 106582:plppr1
uniprot id: A0A3P9CIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

106582:LOC101483128
gene id: 106582:LOC101483128
uniprot id: A0A3P9DC24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:mrpl30
gene id: 106582:mrpl30
uniprot id: A0A3P9D4H8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

106582:LOC101484448
gene id: 106582:LOC101484448
uniprot id: A0A3P9C9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:LOC101465948
gene id: 106582:LOC101465948
uniprot id: A0A3P9D8A9
names: Subcellular Location Annotation
messages: Membrane

106582:rpa3
gene id: 106582:rpa3
uniprot id: A0A3P9CNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

106582:LOC101486103
gene id: 106582:LOC101486103
uniprot id: A0A3P9B4P4
names: Similarity
messages: Belongs to the stathmin family.

106582:il15ra
gene id: 106582:il15ra
uniprot id: A0A3P9CDP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:vamp1
gene id: 106582:vamp1
uniprot id: A0A3P9CP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

106582:LOC101477919
gene id: 106582:LOC101477919
uniprot id: A0A3P9BFY9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101467141
gene id: 106582:LOC101467141
uniprot id: A0A3P9BLL0
names: Subcellular Location Annotation
messages: Membrane

106582:hdhd3
gene id: 106582:hdhd3
uniprot id: A0A3P9CGD6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

106582:lypla2
gene id: 106582:lypla2
uniprot id: A0A3P9DL35
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

106582:LOC101475224
gene id: 106582:LOC101475224
uniprot id: A0A3P9B7L7
uniprot id: A0A3P9B7V8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

106582:LOC101480936
gene id: 106582:LOC101480936
uniprot id: A0A3P9DMB2
names: Similarity
messages: Belongs to the PPDPF family.

106582:LOC101467784
gene id: 106582:LOC101467784
uniprot id: A0A3P9C5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

106582:gngt2
gene id: 106582:gngt2
uniprot id: A0A3P9BC59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101487601
gene id: 106582:LOC101487601
uniprot id: A0A3P9CIT3
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

106582:gkap1
gene id: 106582:gkap1
uniprot id: A0A3P9B850
names: Similarity
messages: Belongs to the GKAP1 family.

106582:LOC101473383
gene id: 106582:LOC101473383
uniprot id: A0A3P9C0R1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101483193
gene id: 106582:LOC101483193
uniprot id: A0A3P9BJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

106582:LOC101478831
gene id: 106582:LOC101478831
uniprot id: A0A3P9BD52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

106582:ncaph2
gene id: 106582:ncaph2
uniprot id: A0A3P9CR54
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

106582:LOC101476159
gene id: 106582:LOC101476159
uniprot id: A0A3P9BC54
names: Similarity
messages: Belongs to the Rab GDI family.

106582:bmp2
gene id: 106582:bmp2
uniprot id: A0A3P9BXG5
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101483471
gene id: 106582:LOC101483471
uniprot id: A0A3P9BMR9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:thyn1
gene id: 106582:thyn1
uniprot id: A0A3P9B9R4
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

106582:alas1
gene id: 106582:alas1
uniprot id: A0A3P9C6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

106582:slc18a1
gene id: 106582:slc18a1
uniprot id: A0A3P9AST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

106582:lg12h12orf49
gene id: 106582:lg12h12orf49
uniprot id: A0A3P9CBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

106582:shkbp1
gene id: 106582:shkbp1
uniprot id: A0A3P9DFP1
names: Similarity
messages: Belongs to the KCTD3 family.

106582:sidt2
gene id: 106582:sidt2
uniprot id: A0A3P9BDC3
uniprot id: A0A3P9BDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

106582:adam10
gene id: 106582:adam10
uniprot id: A0A3P9C924
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:bcl2
gene id: 106582:bcl2
uniprot id: A0A3P9DIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

106582:LOC101465565
gene id: 106582:LOC101465565
uniprot id: A0A3P9DSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:bri3
gene id: 106582:bri3
uniprot id: A0A3P9C5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

106582:LOC101467933
gene id: 106582:LOC101467933
uniprot id: A0A3P9BBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

106582:LOC101465831
gene id: 106582:LOC101465831
uniprot id: A0A3P9DM05
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101468089
gene id: 106582:LOC101468089
uniprot id: A0A3P9D899
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:nfyb
gene id: 106582:nfyb
uniprot id: A0A3P9BJZ0
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

106582:mesd
gene id: 106582:mesd
uniprot id: A0A3P9CLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

106582:rps21
gene id: 106582:rps21
uniprot id: A0A3P9DNU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

106582:LOC101483825
gene id: 106582:LOC101483825
uniprot id: A0A3P9C9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

106582:mvb12a
gene id: 106582:mvb12a
uniprot id: A0A3P9B5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

106582:otop1
gene id: 106582:otop1
uniprot id: A0A3P9DP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

106582:mrpl2
gene id: 106582:mrpl2
uniprot id: A0A3P9BVP0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

106582:LOC101475071
gene id: 106582:LOC101475071
uniprot id: A0A3P9BZJ4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106582:LOC101467328
gene id: 106582:LOC101467328
uniprot id: A0A3P9BVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

106582:nphs1
gene id: 106582:nphs1
uniprot id: A0A3P9C5Z7
uniprot id: A0A3P9C6D9
names: Subcellular Location Annotation
messages: Membrane

106582:snf8
gene id: 106582:snf8
uniprot id: A0A3P9BM36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

106582:zic3
gene id: 106582:zic3
uniprot id: A0A3P9BEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:cwc25
gene id: 106582:cwc25
uniprot id: A0A3P9C3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

106582:rpl13
gene id: 106582:rpl13
uniprot id: A0A3P9CA04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

106582:LOC101478248
gene id: 106582:LOC101478248
uniprot id: A0A3P9CPT4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101471734
gene id: 106582:LOC101471734
uniprot id: A0A3P9ATQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

106582:mns1
gene id: 106582:mns1
uniprot id: A0A3P9C7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

106582:APK84 gp13
gene id: 106582:APK84_gp13
uniprot id: A0A0K2CJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:popdc3
gene id: 106582:popdc3
uniprot id: A0A3P9DH82
names: Similarity
messages: Belongs to the popeye family.

106582:sfr1
gene id: 106582:sfr1
uniprot id: A0A3P9DQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

106582:map3k10
gene id: 106582:map3k10
uniprot id: A0A3P9CJM7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

106582:cul2
gene id: 106582:cul2
uniprot id: A0A3P9CLK4
names: Similarity
messages: Belongs to the cullin family.

106582:grpel1
gene id: 106582:grpel1
uniprot id: A0A3P9BPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

106582:LOC101465930
gene id: 106582:LOC101465930
uniprot id: A0A3P9D123
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:rhbdd3
gene id: 106582:rhbdd3
uniprot id: A0A3P9CN79
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486266
gene id: 106582:LOC101486266
uniprot id: A0A3P9B8D6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

106582:LOC101472972
gene id: 106582:LOC101472972
uniprot id: A0A3P9BVR7
uniprot id: A0A3P9BVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:mtif3
gene id: 106582:mtif3
uniprot id: A0A3P9B763
names: Similarity
messages: Belongs to the IF-3 family.

106582:LOC101464078
gene id: 106582:LOC101464078
uniprot id: A0A3P9AUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:mark3
gene id: 106582:mark3
uniprot id: A0A3P9AXW9
uniprot id: A0A3P9AY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

106582:masp1
gene id: 106582:masp1
uniprot id: A0A3P9AZ70
uniprot id: A0A3P9AZL5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:actl6a
gene id: 106582:actl6a
uniprot id: A0A3P9AYP1
names: Similarity
messages: Belongs to the actin family.

106582:LOC101468340
gene id: 106582:LOC101468340
uniprot id: A0A3P9CHQ4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

106582:LOC101476697
gene id: 106582:LOC101476697
uniprot id: A0A3P9CV87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

106582:tctn1
gene id: 106582:tctn1
uniprot id: A0A3P9CND9
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

106582:LOC101472582
gene id: 106582:LOC101472582
uniprot id: A0A3P9BPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:ppp2r5c
gene id: 106582:ppp2r5c
uniprot id: A0A3P9B8Y5
uniprot id: A0A3P9B8Y9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

106582:rcl1
gene id: 106582:rcl1
uniprot id: A0A3P9CL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

106582:ublcp1
gene id: 106582:ublcp1
uniprot id: A0A3P9ASS6
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

106582:cltrn
gene id: 106582:cltrn
uniprot id: A0A3P9CZG9
names: Subcellular Location Annotation
messages: Membrane

106582:runx3
gene id: 106582:runx3
uniprot id: A0A3P9BEQ4
uniprot id: A0A3P9BER3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101471467
gene id: 106582:LOC101471467
uniprot id: A0A3P9DEC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101487714
gene id: 106582:LOC101487714
uniprot id: A0A3P9CBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

106582:rgmb
gene id: 106582:rgmb
uniprot id: A0A3P9CL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

106582:clcn3
gene id: 106582:clcn3
uniprot id: A0A3P9D040
uniprot id: A0A3P9D097
uniprot id: A0A3P9D1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

106582:grina
gene id: 106582:grina
uniprot id: A0A3P9B7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

106582:thoc7
gene id: 106582:thoc7
uniprot id: A0A3P9C161
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

106582:gadd45b
gene id: 106582:gadd45b
uniprot id: A0A3P9B2H8
names: Similarity
messages: Belongs to the GADD45 family.

106582:ptgr2
gene id: 106582:ptgr2
uniprot id: A0A3P9CBJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

106582:cep76
gene id: 106582:cep76
uniprot id: A0A3P9DHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

106582:LOC101486623
gene id: 106582:LOC101486623
uniprot id: A0A3P9B1I8
names: Similarity
messages: Belongs to the NUPR family.

106582:klc1
gene id: 106582:klc1
uniprot id: A0A3P9AXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

106582:sdk1
gene id: 106582:sdk1
uniprot id: A0A3P9C1Q0
names: Subcellular Location Annotation
messages: Membrane

106582:armc8
gene id: 106582:armc8
uniprot id: A0A3P9D343
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:ttc26
gene id: 106582:ttc26
uniprot id: A0A3P9AST7
names: Similarity
messages: Belongs to the IFT56 family.

106582:LOC101476299
gene id: 106582:LOC101476299
uniprot id: A0A3P9AS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

106582:LOC101475396
gene id: 106582:LOC101475396
uniprot id: A0A3P9CH04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

106582:tm7sf2
gene id: 106582:tm7sf2
uniprot id: A0A3P9C7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

106582:LOC101472505
gene id: 106582:LOC101472505
uniprot id: A0A3P9AXX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:itgav
gene id: 106582:itgav
uniprot id: A0A3P9CYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

106582:tars
gene id: 106582:tars
uniprot id: A0A3P9C4P4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

106582:LOC101470497
gene id: 106582:LOC101470497
uniprot id: A0A3P9CDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

106582:brd1
gene id: 106582:brd1
uniprot id: A0A3P9CFK7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101481522
gene id: 106582:LOC101481522
uniprot id: A0A3P9BBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

106582:swi5
gene id: 106582:swi5
uniprot id: A0A3P9CMI1
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

106582:LOC101469839
gene id: 106582:LOC101469839
uniprot id: A0A3P9BE50
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

106582:LOC101478055
gene id: 106582:LOC101478055
uniprot id: A0A3P9CQ33
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:isoc2
gene id: 106582:isoc2
uniprot id: A0A3P9CIN7
names: Similarity
messages: Belongs to the isochorismatase family.

106582:LOC101467947
gene id: 106582:LOC101467947
uniprot id: A0A3P9DEL8
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

106582:lrit1
gene id: 106582:lrit1
uniprot id: A0A3P9AVA0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101478560
gene id: 106582:LOC101478560
uniprot id: A0A3P9CPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

106582:LOC101464562
gene id: 106582:LOC101464562
uniprot id: A0A3P9C4V7
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:slc35f3
gene id: 106582:slc35f3
uniprot id: A0A3P9BCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

106582:usp30
gene id: 106582:usp30
uniprot id: A0A3P9CEC2
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:LOC101480031
gene id: 106582:LOC101480031
uniprot id: A0A3P9CNK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

106582:LOC101474501
gene id: 106582:LOC101474501
uniprot id: A0A3P9D7E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:prdm12
gene id: 106582:prdm12
uniprot id: A0A3P9ARX4
names: Subcellular Location Annotation
messages: Nucleus

106582:abcg5
gene id: 106582:abcg5
uniprot id: A0A3P9DR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

106582:eef1b2
gene id: 106582:eef1b2
uniprot id: A0A3P9B4Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

106582:LOC101473908
gene id: 106582:LOC101473908
uniprot id: A0A3P9DC84
uniprot id: A0A3P9DCR6
uniprot id: A0A3P9DDB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

106582:LOC101487043
gene id: 106582:LOC101487043
uniprot id: A0A3P9DMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:tmprss6
gene id: 106582:tmprss6
uniprot id: A0A3P9BDP9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: extracellular space

106582:ipo8
gene id: 106582:ipo8
uniprot id: A0A3P9BM45
names: Subcellular Location Annotation
messages: Cytoplasm

106582:leap2
gene id: 106582:leap2
uniprot id: A0A3P9CYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

106582:tomt
gene id: 106582:tomt
uniprot id: A0A3P9BIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

106582:nt5dc2
gene id: 106582:nt5dc2
uniprot id: A0A3P9DLY8
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

106582:LOC101485719
gene id: 106582:LOC101485719
uniprot id: A0A3P9CUV2
names: Similarity
messages: Belongs to the 3-beta-HSD family.

106582:LOC101484727
gene id: 106582:LOC101484727
uniprot id: A0A3P9CI22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101474834
gene id: 106582:LOC101474834
uniprot id: A0A3P9B0G2
names: Similarity
messages: Belongs to the guanylate kinase family.

106582:psd2
gene id: 106582:psd2
uniprot id: A0A3P9BDL0
names: Subcellular Location Annotation
messages: ruffle membrane

106582:erbb2
gene id: 106582:erbb2
uniprot id: A0A3P9CAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

106582:LOC101487706
gene id: 106582:LOC101487706
uniprot id: A0A3P9B891
names: Subcellular Location Annotation
messages: Nucleus

106582:prpf38b
gene id: 106582:prpf38b
uniprot id: A0A3P9DIE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

106582:LOC101477898
gene id: 106582:LOC101477898
uniprot id: A0A3P9CB00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:lig3
gene id: 106582:lig3
uniprot id: A0A3P9BZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

106582:LOC101478889
gene id: 106582:LOC101478889
uniprot id: A0A3P9BKW0
names: Similarity
messages: Belongs to the yippee family.

106582:LOC101468410
gene id: 106582:LOC101468410
uniprot id: A0A3P9DA98
names: Similarity
messages: Belongs to the actin family.

106582:LOC101472880
gene id: 106582:LOC101472880
uniprot id: A0A2Z5VHA9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rps12
gene id: 106582:rps12
uniprot id: A0A3P9CIH7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

106582:LOC101487452
gene id: 106582:LOC101487452
uniprot id: Q78C19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

106582:LOC101486053
gene id: 106582:LOC101486053
uniprot id: A0A3P9CEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

106582:LOC101486730
gene id: 106582:LOC101486730
uniprot id: A0A3P9AUD0
names: Subcellular Location Annotation
messages: Membrane

106582:fam91a1
gene id: 106582:fam91a1
uniprot id: A0A3P9B9J8
names: Similarity
messages: Belongs to the FAM91 family.

106582:LOC101475017
gene id: 106582:LOC101475017
uniprot id: A0A3P9AZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

106582:LOC101480756
gene id: 106582:LOC101480756
uniprot id: A0A3P9BRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

106582:siva1
gene id: 106582:siva1
uniprot id: A0A3P9DP34
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus
messages: Phosphorylated by ABL2/ARG in response to oxidative stress.

106582:LOC101482297
gene id: 106582:LOC101482297
uniprot id: A0A3P9D9V7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

106582:LOC101482769
gene id: 106582:LOC101482769
uniprot id: A0A3P9AW17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

106582:dnmt1
gene id: 106582:dnmt1
uniprot id: A0A3P9CTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

106582:rpl30
gene id: 106582:rpl30
uniprot id: A0A3P9B341
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

106582:LOC101464395
gene id: 106582:LOC101464395
uniprot id: A0A3P9B006
names: Similarity
messages: Belongs to the pleiotrophin family.

106582:LOC101466861
gene id: 106582:LOC101466861
uniprot id: A0A3P9B2Z5
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

106582:ankrd13b
gene id: 106582:ankrd13b
uniprot id: A0A3P9BF96
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

106582:sybu
gene id: 106582:sybu
uniprot id: A0A3P9BZG4
uniprot id: A0A3P9BZU3
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101465610
gene id: 106582:LOC101465610
uniprot id: A0A3P9C9J0
names: Similarity
messages: Belongs to the arrestin family.

106582:serp1
gene id: 106582:serp1
uniprot id: A0A3P9AYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

106582:LOC101466433
gene id: 106582:LOC101466433
uniprot id: A0A3P9CJX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101468454
gene id: 106582:LOC101468454
uniprot id: A0A3P9CK51
names: Similarity
messages: Belongs to the copine family.

106582:hmga2
gene id: 106582:hmga2
uniprot id: A0A3P9CDC0
names: Similarity
messages: Belongs to the HMGA family.

106582:kcnk12
gene id: 106582:kcnk12
uniprot id: A0A3P9BFQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:wnt2
gene id: 106582:wnt2
uniprot id: A0A3P9C7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101466639
gene id: 106582:LOC101466639
uniprot id: A0A3P9B6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

106582:susd5
gene id: 106582:susd5
uniprot id: A0A3P9BBG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pax9
gene id: 106582:pax9
uniprot id: A0A3P9CCF0
names: Subcellular Location Annotation
messages: Nucleus

106582:hoxc5
gene id: 106582:hoxc5
uniprot id: A0A3P9DPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:mknk2
gene id: 106582:mknk2
uniprot id: A0A3P9CTM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101469656
gene id: 106582:LOC101469656
uniprot id: A0A3P9B9R1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:syvn1
gene id: 106582:syvn1
uniprot id: A0A3P9BBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101479735
gene id: 106582:LOC101479735
uniprot id: A0A3P9D7K7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101482122
gene id: 106582:LOC101482122
uniprot id: A0A3P9BIE0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

106582:optn
gene id: 106582:optn
uniprot id: A0A3P9CET9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

106582:cdpf1
gene id: 106582:cdpf1
uniprot id: A0A3P9C1R6
names: Similarity
messages: Belongs to the CDPF1 family.

106582:hat1
gene id: 106582:hat1
uniprot id: A0A3P9BB26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

106582:krtcap2
gene id: 106582:krtcap2
uniprot id: A0A3P9CE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

106582:cfl1
gene id: 106582:cfl1
uniprot id: A0A3P9BAI9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

106582:mpc2
gene id: 106582:mpc2
uniprot id: A0A3P9D604
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

106582:med9
gene id: 106582:med9
uniprot id: A0A3P9C448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:acot13
gene id: 106582:acot13
uniprot id: A0A3P9B5B6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

106582:LOC101482757
gene id: 106582:LOC101482757
uniprot id: A0A3P9AX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101467699
gene id: 106582:LOC101467699
uniprot id: A0A3P9D838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101485256
gene id: 106582:LOC101485256
uniprot id: A0A3P9B9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

106582:LOC101477603
gene id: 106582:LOC101477603
uniprot id: A0A3P9DCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:lancl1
gene id: 106582:lancl1
uniprot id: A0A3P9CCG4
names: Similarity
messages: Belongs to the LanC-like protein family.

106582:tmem218
gene id: 106582:tmem218
uniprot id: A0A3P9DCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

106582:anapc16
gene id: 106582:anapc16
uniprot id: A0A3P9AUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

106582:LOC101479864
gene id: 106582:LOC101479864
uniprot id: A0A3P9BDY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101464910
gene id: 106582:LOC101464910
uniprot id: A0A3P9DN45
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:zdhhc17
gene id: 106582:zdhhc17
uniprot id: A0A3P9BPA2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101479196
gene id: 106582:LOC101479196
uniprot id: A0A3P9DIR9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:nsun3
gene id: 106582:nsun3
uniprot id: A0A3P9AZV0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

106582:LOC101472076
gene id: 106582:LOC101472076
uniprot id: A0A3P9BDR6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:ric3
gene id: 106582:ric3
uniprot id: A0A3P9C331
names: Similarity
messages: Belongs to the ric-3 family.

106582:slc2a8
gene id: 106582:slc2a8
uniprot id: A0A3P9CY36
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:LOC101476741
gene id: 106582:LOC101476741
uniprot id: A0A3P9CV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

106582:LOC101486632
gene id: 106582:LOC101486632
uniprot id: A0A3P9C865
names: Similarity
messages: Belongs to the LRRFIP family.

106582:LOC101464062
gene id: 106582:LOC101464062
uniprot id: A0A3P9CRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

106582:strn4
gene id: 106582:strn4
uniprot id: A0A3P9CHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

106582:recql
gene id: 106582:recql
uniprot id: A0A3P9CGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

106582:hs3st5
gene id: 106582:hs3st5
uniprot id: A0A3P9CFP9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:snd1
gene id: 106582:snd1
uniprot id: A0A3P9BC27
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

106582:sh2b2
gene id: 106582:sh2b2
uniprot id: A0A3P9CJ94
names: Similarity
messages: Belongs to the SH2B adapter family.

106582:LOC101478833
gene id: 106582:LOC101478833
uniprot id: A0A3P9CJW7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482182
gene id: 106582:LOC101482182
uniprot id: A0A3P9C053
names: Similarity
messages: Belongs to the TENT family.

106582:LOC101486267
gene id: 106582:LOC101486267
uniprot id: A0A3P9BNY9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101481569
gene id: 106582:LOC101481569
uniprot id: A0A3P9CMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

106582:LOC101478921
gene id: 106582:LOC101478921
uniprot id: A0A3P9C832
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

106582:LOC101487739
gene id: 106582:LOC101487739
uniprot id: A0A3P9BC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

106582:LOC101465000
gene id: 106582:LOC101465000
uniprot id: A0A3P9AZU1
names: Similarity
messages: Belongs to the WD repeat EBI family.

106582:pnn
gene id: 106582:pnn
uniprot id: A0A3P9BKI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

106582:LOC101470932
gene id: 106582:LOC101470932
uniprot id: A0A3P9BPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

106582:mppe1
gene id: 106582:mppe1
uniprot id: A0A3P9DE36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

106582:etf1
gene id: 106582:etf1
uniprot id: A0A3P9AS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

106582:cpne3
gene id: 106582:cpne3
uniprot id: A0A3P9CKB9
uniprot id: A0A3P9CKX8
names: Similarity
messages: Belongs to the copine family.

106582:LOC101472403
gene id: 106582:LOC101472403
uniprot id: A0A3P9CJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

106582:vsx1
gene id: 106582:vsx1
uniprot id: A0A3P9B5N7
names: Subcellular Location Annotation
messages: Nucleus

106582:gucy1a2
gene id: 106582:gucy1a2
uniprot id: A0A3P9C9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

106582:LOC101486301
gene id: 106582:LOC101486301
uniprot id: A0A3P9CBG8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:slc37a3
gene id: 106582:slc37a3
uniprot id: A0A3P9C1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

106582:pou4f1
gene id: 106582:pou4f1
uniprot id: A0A3P9B845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:LOC101464081
gene id: 106582:LOC101464081
uniprot id: A0A3P9C107
uniprot id: A0A3P9C227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101475175
gene id: 106582:LOC101475175
uniprot id: A0A3P9D9D7
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

106582:LOC101465953
gene id: 106582:LOC101465953
uniprot id: A0A3P9B4D6
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

106582:ube2f
gene id: 106582:ube2f
uniprot id: A0A3P9ATF7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:dmrta1
gene id: 106582:dmrta1
uniprot id: A0A3P9ATW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

106582:g6pc2
gene id: 106582:g6pc2
uniprot id: A0A3P9BE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

106582:LOC101484151
gene id: 106582:LOC101484151
uniprot id: A0A3P9BEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

106582:rbp4
gene id: 106582:rbp4
uniprot id: A0A3P9CDV3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

106582:LOC101467093
gene id: 106582:LOC101467093
uniprot id: A0A3P9BD99
names: Similarity
messages: Belongs to the perilipin family.

106582:ucn
gene id: 106582:ucn
uniprot id: A0A3P9BEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

106582:tpd52l1
gene id: 106582:tpd52l1
uniprot id: A0A3P9C711
uniprot id: A0A3P9C731
names: Similarity
messages: Belongs to the TPD52 family.

106582:LOC101468243
gene id: 106582:LOC101468243
uniprot id: A0A3P9C140
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:LOC101485682
gene id: 106582:LOC101485682
uniprot id: A0A3P9B4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

106582:gpx7
gene id: 106582:gpx7
uniprot id: A0A3P9CKZ7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

106582:eps8l2
gene id: 106582:eps8l2
uniprot id: A0A3P9AU19
names: Similarity
messages: Belongs to the EPS8 family.

106582:LOC101479706
gene id: 106582:LOC101479706
uniprot id: A0A3P9DN16
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

106582:acsf2
gene id: 106582:acsf2
uniprot id: A0A3P9BNC2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

106582:LOC101485085
gene id: 106582:LOC101485085
uniprot id: A0A3P9B5I6
names: Subcellular Location Annotation
messages: Nucleus

106582:blcap
gene id: 106582:blcap
uniprot id: A0A3P9CJF0
names: Similarity
messages: Belongs to the BLCAP family.

106582:LOC101466658
gene id: 106582:LOC101466658
uniprot id: A0A3P9BR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

106582:LOC101475478
gene id: 106582:LOC101475478
uniprot id: A0A3P9BGI7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

106582:prkx
gene id: 106582:prkx
uniprot id: A0A3P9D0X9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101480502
gene id: 106582:LOC101480502
uniprot id: A0A3P9D866
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

106582:mrpl15
gene id: 106582:mrpl15
uniprot id: A0A3P9CRG5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

106582:mical2
gene id: 106582:mical2
uniprot id: A0A3P9CAU4
uniprot id: A0A3P9CBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

106582:taz
gene id: 106582:taz
uniprot id: A0A3P9DP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

106582:LOC101475687
gene id: 106582:LOC101475687
uniprot id: A0A3P9CEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

106582:LOC101475128
gene id: 106582:LOC101475128
uniprot id: A0A3P9CLM3
names: Similarity
messages: Belongs to the copine family.

106582:kcnj5
gene id: 106582:kcnj5
uniprot id: A0A3P9C6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:pold3
gene id: 106582:pold3
uniprot id: A0A3P9DD85
names: Subcellular Location Annotation
messages: Nucleus

106582:mrpl14
gene id: 106582:mrpl14
uniprot id: A0A3P9BR05
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

106582:prtg
gene id: 106582:prtg
uniprot id: A0A3P9C7L9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480559
gene id: 106582:LOC101480559
uniprot id: A0A3P9BJQ8
names: Similarity
messages: Belongs to the EVA1 family.

106582:LOC101468679
gene id: 106582:LOC101468679
uniprot id: A0A3P9D8J0
names: Similarity
messages: Belongs to the TIP41 family.

106582:gins3
gene id: 106582:gins3
uniprot id: A0A3P9CGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

106582:rnf34
gene id: 106582:rnf34
uniprot id: A0A3P9BSY7
uniprot id: A0A3P9BTX0
names: Subcellular Location Annotation
messages: Cell membrane

106582:LOC101477002
gene id: 106582:LOC101477002
uniprot id: A0A3P9CYX0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:eif3l
gene id: 106582:eif3l
uniprot id: A0A3P9BX13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

106582:LOC101486458
gene id: 106582:LOC101486458
uniprot id: A0A3P9CIA1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484714
gene id: 106582:LOC101484714
uniprot id: A0A3P9BKX5
names: Similarity
messages: Belongs to the CAND family.

106582:LOC101481107
gene id: 106582:LOC101481107
uniprot id: A0A3P9CQJ1
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

106582:LOC101484024
gene id: 106582:LOC101484024
uniprot id: A0A3P9DB98
names: Similarity
messages: Belongs to the TASOR family.

106582:LOC101484207
gene id: 106582:LOC101484207
uniprot id: A0A3P9D3B1
uniprot id: A0A3P9D4E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101466237
gene id: 106582:LOC101466237
uniprot id: A0A3P9AXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

106582:LOC101473957
gene id: 106582:LOC101473957
uniprot id: A0A3P9DI89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

106582:LOC101467412
gene id: 106582:LOC101467412
uniprot id: A0A3P9CB27
names: Similarity
messages: Belongs to the RAMP family.

106582:neurl2
gene id: 106582:neurl2
uniprot id: A0A3P9BL97
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101485451
gene id: 106582:LOC101485451
uniprot id: A0A3P9DRH4
names: Similarity
messages: Belongs to the DDIT4 family.

106582:ndufs2
gene id: 106582:ndufs2
uniprot id: A0A3P9BLM5
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

106582:gcm2
gene id: 106582:gcm2
uniprot id: A0A3P9CX69
names: Subcellular Location Annotation
messages: Nucleus

106582:mitfb
gene id: 106582:mitfb
uniprot id: A0A3P9DK28
uniprot id: A0A3P9DL36
uniprot id: A9UJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

106582:cdv3
gene id: 106582:cdv3
uniprot id: A0A3P9CRY1
names: Similarity
messages: Belongs to the CDV3 family.

106582:inka2
gene id: 106582:inka2
uniprot id: A0A3P9BBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

106582:srxn1
gene id: 106582:srxn1
uniprot id: A0A3P9DKW0
names: Similarity
messages: Belongs to the sulfiredoxin family.

106582:LOC101472521
gene id: 106582:LOC101472521
uniprot id: A0A3P9DQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:barx2
gene id: 106582:barx2
uniprot id: A0A3P9C5X3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101476551
gene id: 106582:LOC101476551
uniprot id: A0A3P9DQ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101472263
gene id: 106582:LOC101472263
uniprot id: A0A3P9C7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

106582:suz12
gene id: 106582:suz12
uniprot id: A0A3P9DBH0
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

106582:rps24
gene id: 106582:rps24
uniprot id: A0A3P9DQK1
uniprot id: A0A3P9DSD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

106582:tmem115
gene id: 106582:tmem115
uniprot id: A0A3P9D381
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101482288
gene id: 106582:LOC101482288
uniprot id: A0A3P9C944
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101481773
gene id: 106582:LOC101481773
uniprot id: A0A3P9CR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:LOC101478334
gene id: 106582:LOC101478334
uniprot id: A0A3P9BSF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:retsat
gene id: 106582:retsat
uniprot id: A0A3P9D824
names: Similarity
messages: Belongs to the Rab GDI family.

106582:LOC101478410
gene id: 106582:LOC101478410
uniprot id: A0A3P9DDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

106582:lg9h3orf58
gene id: 106582:lg9h3orf58
uniprot id: A0A3P9D483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

106582:LOC101475684
gene id: 106582:LOC101475684
uniprot id: A0A3P9CEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

106582:LOC101481294
gene id: 106582:LOC101481294
uniprot id: A0A3P9BZT2
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

106582:ltn1
gene id: 106582:ltn1
uniprot id: A0A3P9CUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

106582:LOC101486721
gene id: 106582:LOC101486721
uniprot id: A0A3P9B2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

106582:klhl15
gene id: 106582:klhl15
uniprot id: A0A3P9CZG0
uniprot id: A0A3P9CZK8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101477140
gene id: 106582:LOC101477140
uniprot id: A0A3P9DFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:parp16
gene id: 106582:parp16
uniprot id: A0A3P9B7J1
names: Similarity
messages: Belongs to the ARTD/PARP family.

106582:ddb2
gene id: 106582:ddb2
uniprot id: A0A3P9AS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

106582:odc1
gene id: 106582:odc1
uniprot id: A0A3P9BTA3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

106582:LOC101473820
gene id: 106582:LOC101473820
uniprot id: A0A3P9D8U6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:LOC101476844
gene id: 106582:LOC101476844
uniprot id: A0A3P9BNM1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

106582:utp15
gene id: 106582:utp15
uniprot id: A0A3P9BVR0
names: Subcellular Location Annotation
messages: nucleolus

106582:prr5l
gene id: 106582:prr5l
uniprot id: A0A3P9D881
names: Similarity
messages: Belongs to the PROTOR family.

106582:LOC101474012
gene id: 106582:LOC101474012
uniprot id: A0A3P9BX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

106582:trappc4
gene id: 106582:trappc4
uniprot id: A0A3P9C4B5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

106582:ptpre
gene id: 106582:ptpre
uniprot id: A0A3P9AYW9
uniprot id: A0A3P9AYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

106582:map2k1
gene id: 106582:map2k1
uniprot id: A0A3P9D8E2
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101482269
gene id: 106582:LOC101482269
uniprot id: A0A3P9C1Z8
names: Subcellular Location Annotation
messages: Nucleus

106582:barx1
gene id: 106582:barx1
uniprot id: A0A3P9BFZ1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101476127
gene id: 106582:LOC101476127
uniprot id: A0A3P9ATV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101486464
gene id: 106582:LOC101486464
uniprot id: A0A3P9CHJ3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

106582:LOC101465522
gene id: 106582:LOC101465522
uniprot id: A0A3P9DNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

106582:LOC101480042
gene id: 106582:LOC101480042
uniprot id: A0A3P9C401
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101480422
gene id: 106582:LOC101480422
uniprot id: A0A3P9BF10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

106582:LOC101482418
gene id: 106582:LOC101482418
uniprot id: A0A3P9D0N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

106582:rrad
gene id: 106582:rrad
uniprot id: A0A3P9AZR8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

106582:LOC101479206
gene id: 106582:LOC101479206
uniprot id: A0A3P9C866
names: Similarity
messages: Belongs to the GDNFR family.

106582:LOC101477682
gene id: 106582:LOC101477682
uniprot id: A0A3P9C2J3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

106582:kpna4
gene id: 106582:kpna4
uniprot id: A0A3P9ARD8
names: Similarity
messages: Belongs to the importin alpha family.

106582:LOC101479044
gene id: 106582:LOC101479044
uniprot id: A0A3P9CC94
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

106582:capzb
gene id: 106582:capzb
uniprot id: A0A3P9BY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

106582:LOC101481514
gene id: 106582:LOC101481514
uniprot id: A0A3P9D8L7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101484390
gene id: 106582:LOC101484390
uniprot id: A0A3P9AS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

106582:LOC101485583
gene id: 106582:LOC101485583
uniprot id: A0A3P9ATD3
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

106582:LOC101470927
gene id: 106582:LOC101470927
uniprot id: A0A3P9CUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

106582:LOC101483445
gene id: 106582:LOC101483445
uniprot id: A0A3P9DNL9
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

106582:rasgrp2
gene id: 106582:rasgrp2
uniprot id: A0A3P9BMD3
names: Similarity
messages: Belongs to the RASGRP family.

106582:LOC101468689
gene id: 106582:LOC101468689
uniprot id: A0A3P9BTV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

106582:chst10
gene id: 106582:chst10
uniprot id: A0A3P9BJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:eme2
gene id: 106582:eme2
uniprot id: A0A3P9C0E4
names: Similarity
messages: Belongs to the EME1/MMS4 family.

106582:oxa1l
gene id: 106582:oxa1l
uniprot id: A0A3P9D2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

106582:LOC101483548
gene id: 106582:LOC101483548
uniprot id: A0A3P9B4X8
names: Similarity
messages: Belongs to the ependymin family.

106582:LOC101472921
gene id: 106582:LOC101472921
uniprot id: A0A3P9BJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:kynu
gene id: 106582:kynu
uniprot id: A0A3P9CFM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101464056
gene id: 106582:LOC101464056
uniprot id: A0A3P9DA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

106582:chd3
gene id: 106582:chd3
uniprot id: A0A3P9D1R1
uniprot id: A0A3P9D344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

106582:hoxb3
gene id: 106582:hoxb3
uniprot id: A0A3P9BLQ3
names: Subcellular Location Annotation
messages: Nucleus

106582:acer3
gene id: 106582:acer3
uniprot id: A0A3P9DAP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101472854
gene id: 106582:LOC101472854
uniprot id: A0A3P9C6C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:LOC101467726
gene id: 106582:LOC101467726
uniprot id: A0A3P9C7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

106582:LOC101477894
gene id: 106582:LOC101477894
uniprot id: A0A3P9DJD5
uniprot id: A0A3P9DJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

106582:LOC101478880
gene id: 106582:LOC101478880
uniprot id: A0A3P9CT47
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:APK84 gp05
gene id: 106582:APK84_gp05
uniprot id: A0A0K2CIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101485676
gene id: 106582:LOC101485676
uniprot id: A0A3P9CGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

106582:tmem8b
gene id: 106582:tmem8b
uniprot id: A0A3P9C562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

106582:LOC101481929
gene id: 106582:LOC101481929
uniprot id: A0A3P9D0T0
names: Similarity
messages: Belongs to the thioredoxin family.

106582:zfyve28
gene id: 106582:zfyve28
uniprot id: A0A3P9BL20
uniprot id: A0A3P9BLW3
names: Similarity
messages: Belongs to the lst-2 family.

106582:LOC101464814
gene id: 106582:LOC101464814
uniprot id: A0A3P9DMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

106582:LOC101467683
gene id: 106582:LOC101467683
uniprot id: A0A3P9CFI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:six1
gene id: 106582:six1
uniprot id: A0A3P9BJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

106582:syngr1
gene id: 106582:syngr1
uniprot id: A0A3P9BDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:LOC101480329
gene id: 106582:LOC101480329
uniprot id: A0A3P9C4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

106582:LOC101468349
gene id: 106582:LOC101468349
uniprot id: A0A3P9BUY5
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

106582:LOC101484775
gene id: 106582:LOC101484775
uniprot id: A0A3P9DGH1
names: Subcellular Location Annotation
messages: Membrane

106582:ppp2ca
gene id: 106582:ppp2ca
uniprot id: A0A3P9BPD8
names: Similarity
messages: Belongs to the PPP phosphatase family.

106582:LOC101486336
gene id: 106582:LOC101486336
uniprot id: A0A3P9AUP8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101466626
gene id: 106582:LOC101466626
uniprot id: A0A3P9C4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:rab5if
gene id: 106582:rab5if
uniprot id: A0A3P9DMN4
names: Subcellular Location Annotation
messages: Membrane

106582:adora2b
gene id: 106582:adora2b
uniprot id: A0A3P9BHZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101463593
gene id: 106582:LOC101463593
uniprot id: A0A3P9BQV3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

106582:aldh1a2
gene id: 106582:aldh1a2
uniprot id: A0A3P9C7V4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:casc3
gene id: 106582:casc3
uniprot id: A0A3P9B4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

106582:acly
gene id: 106582:acly
uniprot id: A0A3P9D8X0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

106582:setd2
gene id: 106582:setd2
uniprot id: A0A3P9CBQ2
uniprot id: A0A3P9CBQ3
names: Subcellular Location Annotation
messages: Nucleus

106582:trap1
gene id: 106582:trap1
uniprot id: A0A3P9B6Y9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

106582:LOC101469258
gene id: 106582:LOC101469258
uniprot id: A0A3P9CK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

106582:LOC101482565
gene id: 106582:LOC101482565
uniprot id: A0A3P9C1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

106582:tshz2
gene id: 106582:tshz2
uniprot id: A0A3P9DA31
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

106582:smpd1
gene id: 106582:smpd1
uniprot id: A0A3P9CUM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

106582:LOC101471699
gene id: 106582:LOC101471699
uniprot id: A0A3P9BQ38
names: Similarity
messages: Belongs to the CBP3 family.

106582:nfib
gene id: 106582:nfib
uniprot id: A0A3P9AZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

106582:LOC101466593
gene id: 106582:LOC101466593
uniprot id: A0A3P9DIQ4
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101465864
gene id: 106582:LOC101465864
uniprot id: A0A3P9DD66
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:LOC101479565
gene id: 106582:LOC101479565
uniprot id: A0A3P9BF00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101480244
gene id: 106582:LOC101480244
uniprot id: A0A3P9DPV1
names: Subcellular Location Annotation
messages: Nucleus

106582:dock4
gene id: 106582:dock4
uniprot id: A0A3P9C0C4
names: Similarity
messages: Belongs to the DOCK family.

106582:LOC101468446
gene id: 106582:LOC101468446
uniprot id: A0A3P9AVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

106582:tnfaip1
gene id: 106582:tnfaip1
uniprot id: A0A3P9CVN3
names: Similarity
messages: Belongs to the BACURD family.

106582:lmbr1l
gene id: 106582:lmbr1l
uniprot id: A0A3P9DPS3
names: Similarity
messages: Belongs to the LIMR family.

106582:LOC101477753
gene id: 106582:LOC101477753
uniprot id: A0A3P9CYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

106582:LOC101464621
gene id: 106582:LOC101464621
uniprot id: A0A3P9C6Y0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

106582:LOC101473229
gene id: 106582:LOC101473229
uniprot id: A0A3P9DRT5
names: Subcellular Location Annotation
messages: Nucleus

106582:tmem39a
gene id: 106582:tmem39a
uniprot id: A0A3P9BD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

106582:luc7l
gene id: 106582:luc7l
uniprot id: A0A3P9BY11
names: Similarity
messages: Belongs to the Luc7 family.

106582:polr2g
gene id: 106582:polr2g
uniprot id: A0A3P9B4F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

106582:LOC101486599
gene id: 106582:LOC101486599
uniprot id: A0A3P9CIR2
uniprot id: A0A3P9CJ57
names: Similarity
messages: Belongs to the epsin family.

106582:LOC101470867
gene id: 106582:LOC101470867
uniprot id: A0A3P9DJ49
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

106582:LOC101467303
gene id: 106582:LOC101467303
uniprot id: A0A3P9DB32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101471662
gene id: 106582:LOC101471662
uniprot id: A0A3P9BUL5
uniprot id: A0A3P9BVD0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101474770
gene id: 106582:LOC101474770
uniprot id: A0A3P9D962
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

106582:mtnr1a
gene id: 106582:mtnr1a
uniprot id: A0A3P9BIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

106582:cnih3
gene id: 106582:cnih3
uniprot id: A0A3P9CDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

106582:rrm2b
gene id: 106582:rrm2b
uniprot id: A0A3P9B3G7
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

106582:LOC101480149
gene id: 106582:LOC101480149
uniprot id: A0A3P9DIN9
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

106582:drd2
gene id: 106582:drd2
uniprot id: A0A3P9CG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101476374
gene id: 106582:LOC101476374
uniprot id: A0A3P9B6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

106582:cck
gene id: 106582:cck
uniprot id: A0A3P9B1D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

106582:adgra3
gene id: 106582:adgra3
uniprot id: A0A3P9AWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

106582:LOC101472041
gene id: 106582:LOC101472041
uniprot id: A0A3P9CCX6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

106582:LOC101472306
gene id: 106582:LOC101472306
uniprot id: A0A3P9DK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:bckdk
gene id: 106582:bckdk
uniprot id: A0A3P9BVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

106582:crbn
gene id: 106582:crbn
uniprot id: A0A3P9BQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

106582:orc4
gene id: 106582:orc4
uniprot id: A0A3P9CFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

106582:LOC101479166
gene id: 106582:LOC101479166
uniprot id: A0A3P9BNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

106582:LOC101473018
gene id: 106582:LOC101473018
uniprot id: A0A3P9CG59
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101466415
gene id: 106582:LOC101466415
uniprot id: A0A3P9DKN2
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476128
gene id: 106582:LOC101476128
uniprot id: A0A3P9BTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101473746
gene id: 106582:LOC101473746
uniprot id: A0A3P9BFC6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

106582:sh3yl1
gene id: 106582:sh3yl1
uniprot id: A0A3P9C4M3
names: Similarity
messages: Belongs to the SH3YL1 family.

106582:ppm1a
gene id: 106582:ppm1a
uniprot id: A0A3P9BIZ4
uniprot id: A0A3P9BJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

106582:LOC101481215
gene id: 106582:LOC101481215
uniprot id: A0A3P9CDL4
names: Subcellular Location Annotation
messages: Nucleus

106582:adra2a
gene id: 106582:adra2a
uniprot id: A0A3P9B1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:slc25a42
gene id: 106582:slc25a42
uniprot id: A0A3P9BVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:rhpn2
gene id: 106582:rhpn2
uniprot id: A0A3P9B795
names: Similarity
messages: Belongs to the RHPN family.

106582:plxna2
gene id: 106582:plxna2
uniprot id: A0A3P9DMY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101479849
gene id: 106582:LOC101479849
uniprot id: A0A3P9B7I4
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

106582:cmc1
gene id: 106582:cmc1
uniprot id: A0A3P9BEB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

106582:pclaf
gene id: 106582:pclaf
uniprot id: A0A3P9AZM8
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

106582:pdss2
gene id: 106582:pdss2
uniprot id: A0A3P9BNU7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

106582:LOC101477305
gene id: 106582:LOC101477305
uniprot id: A0A3P9BEY9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

106582:smad7
gene id: 106582:smad7
uniprot id: A0A3P9CVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:kcnk1
gene id: 106582:kcnk1
uniprot id: A0A3P9BCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

106582:ube2m
gene id: 106582:ube2m
uniprot id: A0A3P9B748
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:rps16
gene id: 106582:rps16
uniprot id: A0A3P9AXW0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

106582:edn1
gene id: 106582:edn1
uniprot id: A0A3P9DK84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

106582:etfrf1
gene id: 106582:etfrf1
uniprot id: A0A3P9CQN8
names: Similarity
messages: Belongs to the complex I LYR family.

106582:atp6v1c1
gene id: 106582:atp6v1c1
uniprot id: A0A3P9DI29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

106582:srpx2
gene id: 106582:srpx2
uniprot id: A0A3P9BIA6
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

106582:LOC101477779
gene id: 106582:LOC101477779
uniprot id: A0A3P9BLR4
names: Similarity
messages: Belongs to the FAM20 family.

106582:timm8a
gene id: 106582:timm8a
uniprot id: A0A3P9BNQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

106582:hacd2
gene id: 106582:hacd2
uniprot id: A0A3P9CT30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:cnot11
gene id: 106582:cnot11
uniprot id: A0A3P9CY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101473785
gene id: 106582:LOC101473785
uniprot id: A0A3P9DN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

106582:eif3i
gene id: 106582:eif3i
uniprot id: A0A3P9AST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

106582:LOC101466573
gene id: 106582:LOC101466573
uniprot id: A0A3P9C264
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:plxnd1
gene id: 106582:plxnd1
uniprot id: A0A3P9ARX3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:tinagl1
gene id: 106582:tinagl1
uniprot id: A0A3P9BAT5
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:dr1
gene id: 106582:dr1
uniprot id: A0A3P9BU30
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

106582:LOC101480703
gene id: 106582:LOC101480703
uniprot id: A0A3P9B9R0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:snrpd1
gene id: 106582:snrpd1
uniprot id: A0A3P9B857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

106582:LOC101486701
gene id: 106582:LOC101486701
uniprot id: A0A3P9CEL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

106582:ddx49
gene id: 106582:ddx49
uniprot id: A0A3P9CJ25
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:LOC101467006
gene id: 106582:LOC101467006
uniprot id: A0A3P9CX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

106582:LOC101466239
gene id: 106582:LOC101466239
uniprot id: A0A3P9B4F2
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

106582:LOC101481606
gene id: 106582:LOC101481606
uniprot id: A0A3P9BC73
names: Similarity
messages: Belongs to the SOGA family.

106582:LOC101478021
gene id: 106582:LOC101478021
uniprot id: A0A3P9C1J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:ensa
gene id: 106582:ensa
uniprot id: A0A3P9BVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

106582:LOC101480970
gene id: 106582:LOC101480970
uniprot id: A0A3P9DSA7
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

106582:trit1
gene id: 106582:trit1
uniprot id: A0A3P9BZC0
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

106582:stxbp2
gene id: 106582:stxbp2
uniprot id: A0A3P9C965
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

106582:LOC101467692
gene id: 106582:LOC101467692
uniprot id: A0A3P9DS17
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101473416
gene id: 106582:LOC101473416
uniprot id: A0A3P9C0V2
names: Similarity
messages: Belongs to the BTG family.

106582:bysl
gene id: 106582:bysl
uniprot id: A0A3P9BYG4
names: Similarity
messages: Belongs to the bystin family.

106582:LOC101473672
gene id: 106582:LOC101473672
uniprot id: A0A3P9DLU7
names: Similarity
messages: Belongs to the FAM110 family.

106582:LOC101465019
gene id: 106582:LOC101465019
uniprot id: A0A3P9CB13
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101482942
gene id: 106582:LOC101482942
uniprot id: A0A3P9CBY8
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

106582:rictor
gene id: 106582:rictor
uniprot id: A0A3P9BUC6
names: Similarity
messages: Belongs to the RICTOR family.

106582:slc29a3
gene id: 106582:slc29a3
uniprot id: A0A3P9BMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

106582:LOC101485691
gene id: 106582:LOC101485691
uniprot id: A0A3P9D9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:kdm7a
gene id: 106582:kdm7a
uniprot id: A0A3P9B1P0
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

106582:tmod1
gene id: 106582:tmod1
uniprot id: A0A3P9AZW2
names: Subcellular Location Annotation
messages: cytoskeleton

106582:hoxc11
gene id: 106582:hoxc11
uniprot id: A0A3P9DPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:LOC101466776
gene id: 106582:LOC101466776
uniprot id: A0A3P9BFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:cenpm
gene id: 106582:cenpm
uniprot id: A0A3P9DBA1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101469550
gene id: 106582:LOC101469550
uniprot id: A0A3P9D980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

106582:LOC101474550
gene id: 106582:LOC101474550
uniprot id: A0A3P9CBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

106582:txnl4a
gene id: 106582:txnl4a
uniprot id: A0A3P9C0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

106582:stat3
gene id: 106582:stat3
uniprot id: A0A3P9D8M6
uniprot id: A0A3P9D8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101480587
gene id: 106582:LOC101480587
uniprot id: A0A3P9ATV6
names: Subcellular Location Annotation
messages: Membrane

106582:cnot8
gene id: 106582:cnot8
uniprot id: A0A3P9C1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

106582:acaa1
gene id: 106582:acaa1
uniprot id: A0A3P9C7W3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106582:eef1akmt2
gene id: 106582:eef1akmt2
uniprot id: A0A3P9DRU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

106582:calcr
gene id: 106582:calcr
uniprot id: A0A3P9BM27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

106582:edil3
gene id: 106582:edil3
uniprot id: A0A3P9CAX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rpl35a
gene id: 106582:rpl35a
uniprot id: A0A3P9AYB6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

106582:psmc1
gene id: 106582:psmc1
uniprot id: A0A3P9BDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

106582:lmbr1
gene id: 106582:lmbr1
uniprot id: A0A3P9ARM3
names: Similarity
messages: Belongs to the LIMR family.

106582:fam214a
gene id: 106582:fam214a
uniprot id: A0A3P9BK87
names: Similarity
messages: Belongs to the FAM214 family.

106582:hspa4l
gene id: 106582:hspa4l
uniprot id: A0A3P9BLM3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:LOC101468319
gene id: 106582:LOC101468319
uniprot id: A0A3P9BVX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:adgrg6
gene id: 106582:adgrg6
uniprot id: A0A3P9C9R3
uniprot id: A0A3P9C9S5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:nol10
gene id: 106582:nol10
uniprot id: A0A3P9BSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

106582:LOC101482407
gene id: 106582:LOC101482407
uniprot id: A0A3P9C0D6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101474152
gene id: 106582:LOC101474152
uniprot id: A0A3P9CSB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC101481440
gene id: 106582:LOC101481440
uniprot id: A0A3P9AZQ9
uniprot id: A0A3P9AZS6
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

106582:sap30l
gene id: 106582:sap30l
uniprot id: A0A3P9C138
names: Similarity
messages: Belongs to the SAP30 family.

106582:hsf2
gene id: 106582:hsf2
uniprot id: A0A3P9CBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

106582:ei24
gene id: 106582:ei24
uniprot id: A0A3P9D9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

106582:irx3
gene id: 106582:irx3
uniprot id: A0A3P9BGC3
uniprot id: A0A3P9BGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

106582:cdk10
gene id: 106582:cdk10
uniprot id: A0A3P9CDU5
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:tma16
gene id: 106582:tma16
uniprot id: A0A3P9BNG9
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

106582:pgls
gene id: 106582:pgls
uniprot id: A0A3P9C920
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

106582:mmd
gene id: 106582:mmd
uniprot id: A0A3P9ASU8
uniprot id: A0A3P9ASW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:LOC101477134
gene id: 106582:LOC101477134
uniprot id: A0A3P9CE84
names: Similarity
messages: Belongs to the S-100 family.

106582:tmem161a
gene id: 106582:tmem161a
uniprot id: A0A3P9BW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

106582:hps5
gene id: 106582:hps5
uniprot id: A0A3P9AVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

106582:LOC101482965
gene id: 106582:LOC101482965
uniprot id: A0A3P9BGM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101480034
gene id: 106582:LOC101480034
uniprot id: A0A3P9BAP5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:LOC101463613
gene id: 106582:LOC101463613
uniprot id: A0A3P9BV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

106582:zic1
gene id: 106582:zic1
uniprot id: A0A3P9CNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:hint1
gene id: 106582:hint1
uniprot id: A0A3P9DR59
names: Similarity
messages: Belongs to the HINT family.

106582:nrm
gene id: 106582:nrm
uniprot id: A0A3P9DM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

106582:slc26a11
gene id: 106582:slc26a11
uniprot id: A0A3P9BL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

106582:pus7
gene id: 106582:pus7
uniprot id: A0A3P9BQQ5
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

106582:arg2
gene id: 106582:arg2
uniprot id: A0A3P9BYY7
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

106582:cass4
gene id: 106582:cass4
uniprot id: A0A3P9BF89
uniprot id: A0A3P9BF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

106582:tmem184c
gene id: 106582:tmem184c
uniprot id: A0A3P9BQA9
names: Subcellular Location Annotation
messages: Membrane

106582:st6galnac3
gene id: 106582:st6galnac3
uniprot id: A0A3P9DD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:LOC101486541
gene id: 106582:LOC101486541
uniprot id: A0A3P9CDY5
names: Similarity
messages: Belongs to the pellino family.

106582:dync1i1
gene id: 106582:dync1i1
uniprot id: A0A3P9BNJ3
uniprot id: A0A3P9BNM3
names: Similarity
messages: Belongs to the dynein intermediate chain family.

106582:hdgfl2
gene id: 106582:hdgfl2
uniprot id: A0A3P9BPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

106582:LOC101464334
gene id: 106582:LOC101464334
uniprot id: A0A3P9CX90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

106582:LOC101469142
gene id: 106582:LOC101469142
uniprot id: A0A3P9DIA8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101472255
gene id: 106582:LOC101472255
uniprot id: A0A3P9CVY2
uniprot id: A0A3P9CX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

106582:dusp5
gene id: 106582:dusp5
uniprot id: A0A3P9B2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

106582:LOC101476492
gene id: 106582:LOC101476492
uniprot id: A0A3P9B0G0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

106582:pno1
gene id: 106582:pno1
uniprot id: A0A3P9DRA8
names: Similarity
messages: Belongs to the PNO1 family.

106582:lg12h9orf78
gene id: 106582:lg12h9orf78
uniprot id: A0A3P9C313
names: Similarity
messages: Belongs to the TLS1 family.

106582:LOC101485761
gene id: 106582:LOC101485761
uniprot id: A0A3P9CDG1
names: Subcellular Location Annotation
messages: Membrane

106582:crhbp
gene id: 106582:crhbp
uniprot id: A0A3P9BGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

106582:LOC101485397
gene id: 106582:LOC101485397
uniprot id: A0A3P9C463
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

106582:xk
gene id: 106582:xk
uniprot id: A0A3P9D5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

106582:LOC101469992
gene id: 106582:LOC101469992
uniprot id: A0A3P9C7Z2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:frk
gene id: 106582:frk
uniprot id: A0A3P9CGK3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:mif
gene id: 106582:mif
uniprot id: A0A3P9B017
names: Similarity
messages: Belongs to the MIF family.

106582:LOC101487155
gene id: 106582:LOC101487155
uniprot id: Q78BQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

106582:LOC101468104
gene id: 106582:LOC101468104
uniprot id: A0A3P9C5V0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

106582:LOC101482115
gene id: 106582:LOC101482115
uniprot id: A0A3P9CCS7
names: Similarity
messages: Belongs to the serpin family.

106582:lmnb2
gene id: 106582:lmnb2
uniprot id: A0A3P9CQD7
names: Similarity
messages: Belongs to the intermediate filament family.

106582:fgf11
gene id: 106582:fgf11
uniprot id: A0A3P9BAJ3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101483392
gene id: 106582:LOC101483392
uniprot id: A0A3P9C897
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

106582:LOC101487903
gene id: 106582:LOC101487903
uniprot id: A0A3P9C5W8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

106582:LOC101474504
gene id: 106582:LOC101474504
uniprot id: A0A3P9BGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

106582:LOC101464288
gene id: 106582:LOC101464288
uniprot id: A0A3P9DL69
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:LOC101479026
gene id: 106582:LOC101479026
uniprot id: A0A3P9ARR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:med24
gene id: 106582:med24
uniprot id: A0A3P9BTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

106582:cdkal1
gene id: 106582:cdkal1
uniprot id: A0A3P9DHQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

106582:polr2i
gene id: 106582:polr2i
uniprot id: A0A3P9C672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

106582:traf2
gene id: 106582:traf2
uniprot id: A0A3P9CT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

106582:lin9
gene id: 106582:lin9
uniprot id: A0A3P9CK07
names: Similarity
messages: Belongs to the lin-9 family.

106582:hdac4
gene id: 106582:hdac4
uniprot id: A0A3P9CJB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

106582:susd6
gene id: 106582:susd6
uniprot id: A0A3P9B3Z0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:nubp2
gene id: 106582:nubp2
uniprot id: A0A3P9C0H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

106582:LOC101474186
gene id: 106582:LOC101474186
uniprot id: A0A3P9DE58
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

106582:APK84 gp07
gene id: 106582:APK84_gp07
uniprot id: A0A0K2CJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

106582:LOC101476981
gene id: 106582:LOC101476981
uniprot id: A0A3P9B2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cytoplasm
messages: Nucleus

106582:LOC101471273
gene id: 106582:LOC101471273
uniprot id: A0A3P9D9D1
names: Similarity
messages: Belongs to the dapper family.

106582:pfas
gene id: 106582:pfas
uniprot id: A0A3P9CVQ5
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

106582:myf6
gene id: 106582:myf6
uniprot id: A0A3P9AYJ5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

106582:ap1b1
gene id: 106582:ap1b1
uniprot id: A0A3P9CNE8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

106582:LOC101482688
gene id: 106582:LOC101482688
uniprot id: A0A3P9CCS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

106582:rfc4
gene id: 106582:rfc4
uniprot id: A0A3P9BZ61
names: Similarity
messages: Belongs to the activator 1 small subunits family.

106582:sumf2
gene id: 106582:sumf2
uniprot id: A0A3P9DG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

106582:piwil2
gene id: 106582:piwil2
uniprot id: A0A3P9CTJ9
names: Similarity
messages: Belongs to the argonaute family.

106582:sgms2
gene id: 106582:sgms2
uniprot id: A0A3P9CVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

106582:slc24a5
gene id: 106582:slc24a5
uniprot id: A0A3P9C1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

106582:LOC101466474
gene id: 106582:LOC101466474
uniprot id: A0A3P9BIT0
uniprot id: A0A3P9BJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

106582:pebp4
gene id: 106582:pebp4
uniprot id: A0A3P9C3U3
uniprot id: A0A3P9C4K9
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

106582:LOC101485353
gene id: 106582:LOC101485353
uniprot id: A0A3P9CJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

106582:prickle2
gene id: 106582:prickle2
uniprot id: A0A3P9C0V8
uniprot id: A0A3P9C0Y7
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

106582:cnot10
gene id: 106582:cnot10
uniprot id: A0A3P9DGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

106582:LOC101486021
gene id: 106582:LOC101486021
uniprot id: A0A3P9BQI3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

106582:polr2k
gene id: 106582:polr2k
uniprot id: A0A3P9B348
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

106582:ilf3
gene id: 106582:ilf3
uniprot id: A0A3P9AZJ6
uniprot id: A0A3P9AZP5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:ncdn
gene id: 106582:ncdn
uniprot id: A0A3P9DLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

106582:mthfd1
gene id: 106582:mthfd1
uniprot id: A0A3P9DN63
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

106582:pde3b
gene id: 106582:pde3b
uniprot id: A0A3P9ARN7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:tdp1
gene id: 106582:tdp1
uniprot id: A0A3P9B9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

106582:e2f7
gene id: 106582:e2f7
uniprot id: A0A3P9BNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

106582:rab3c
gene id: 106582:rab3c
uniprot id: A0A3P9BD29
uniprot id: A0A3P9BD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

106582:LOC101468173
gene id: 106582:LOC101468173
uniprot id: A0A3P9AYR0
names: Subcellular Location Annotation
messages: Membrane

106582:sgcb
gene id: 106582:sgcb
uniprot id: A0A3P9CXZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

106582:copz1
gene id: 106582:copz1
uniprot id: A0A3P9DQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

106582:lipg
gene id: 106582:lipg
uniprot id: A0A3P9C3B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101471760
gene id: 106582:LOC101471760
uniprot id: A0A3P9B5E9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

106582:vipr1
gene id: 106582:vipr1
uniprot id: A0A3P9CW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

106582:LOC101463980
gene id: 106582:LOC101463980
uniprot id: A0A3P9B9H9
names: Subcellular Location Annotation
messages: Membrane

106582:pltp
gene id: 106582:pltp
uniprot id: A0A3P9BP38
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

106582:irak1bp1
gene id: 106582:irak1bp1
uniprot id: A0A3P9BUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

106582:slc26a2
gene id: 106582:slc26a2
uniprot id: A0A3P9B6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

106582:lrrn3
gene id: 106582:lrrn3
uniprot id: A0A3P9C0N7
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101466396
gene id: 106582:LOC101466396
uniprot id: A0A3P9B8I5
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101467340
gene id: 106582:LOC101467340
uniprot id: A0A3P9BJ41
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:adamts1
gene id: 106582:adamts1
uniprot id: A0A3P9BBH0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:LOC101466519
gene id: 106582:LOC101466519
uniprot id: A0A3P9DT90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rpl18
gene id: 106582:rpl18
uniprot id: A0A3P9CH95
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

106582:ap1g1
gene id: 106582:ap1g1
uniprot id: A0A3P9C9F7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

106582:LOC101475444
gene id: 106582:LOC101475444
uniprot id: A0A3P9D4D8
names: Similarity
messages: Belongs to the globin family.

106582:b3gnt2
gene id: 106582:b3gnt2
uniprot id: A0A3P9DPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101468598
gene id: 106582:LOC101468598
uniprot id: A0A3P9BJQ1
uniprot id: A0A3P9BJQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:mogs
gene id: 106582:mogs
uniprot id: A0A3P9CW16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

106582:LOC101471904
gene id: 106582:LOC101471904
uniprot id: A0A3P9B920
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484155
gene id: 106582:LOC101484155
uniprot id: A0A3P9BPE7
uniprot id: A0A3P9BPI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

106582:ndufs5
gene id: 106582:ndufs5
uniprot id: A0A3P9DJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

106582:abraxas1
gene id: 106582:abraxas1
uniprot id: A0A3P9DAT4
names: Subcellular Location Annotation
messages: Nucleus

106582:stac
gene id: 106582:stac
uniprot id: A0A3P9BA25
names: Subcellular Location Annotation
messages: sarcolemma

106582:LOC101468926
gene id: 106582:LOC101468926
uniprot id: A0A3P9BM50
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478044
gene id: 106582:LOC101478044
uniprot id: A0A3P9CYK2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

106582:LOC101481074
gene id: 106582:LOC101481074
uniprot id: A0A3P9DBF2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

106582:LOC101476328
gene id: 106582:LOC101476328
uniprot id: A0A3P9BSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

106582:LOC101479208
gene id: 106582:LOC101479208
uniprot id: A0A3P9CNM0
names: Similarity
messages: Belongs to the TGF-beta family.

106582:snx21
gene id: 106582:snx21
uniprot id: A0A3P9DNB5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

106582:LOC101464908
gene id: 106582:LOC101464908
uniprot id: A0A3P9C5L3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

106582:LOC101473896
gene id: 106582:LOC101473896
uniprot id: A0A3P9BMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

106582:crygs
gene id: 106582:crygs
uniprot id: A0A3P9D321
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101477871
gene id: 106582:LOC101477871
uniprot id: A0A3P9DA84
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

106582:LOC101475383
gene id: 106582:LOC101475383
uniprot id: A0A3P9CDC2
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

106582:LOC101478374
gene id: 106582:LOC101478374
uniprot id: A0A3P9CTF9
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:l1cam
gene id: 106582:l1cam
uniprot id: A0A3P9DPV4
uniprot id: A0A3P9DQD7
uniprot id: A0A3P9DQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

106582:lg3h11orf68
gene id: 106582:lg3h11orf68
uniprot id: A0A3P9BN33
names: Similarity
messages: Belongs to the UPF0696 family.

106582:zdhhc13
gene id: 106582:zdhhc13
uniprot id: A0A3P9CB62
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101469715
gene id: 106582:LOC101469715
uniprot id: A0A3P9C6V1
uniprot id: A0A3P9C798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

106582:dbnl
gene id: 106582:dbnl
uniprot id: A0A3P9BYS1
uniprot id: A0A3P9BYU6
uniprot id: A0A3P9BZ01
uniprot id: A0A3P9BZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

106582:LOC101487217
gene id: 106582:LOC101487217
uniprot id: A0A3P9DEL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:eef1akmt1
gene id: 106582:eef1akmt1
uniprot id: A0A3P9CUA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

106582:LOC101481213
gene id: 106582:LOC101481213
uniprot id: A0A3P9BU81
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

106582:LOC101481666
gene id: 106582:LOC101481666
uniprot id: A0A3P9CY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

106582:foxn3
gene id: 106582:foxn3
uniprot id: A0A3P9BEC5
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473206
gene id: 106582:LOC101473206
uniprot id: A0A3P9CWU8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

106582:pdcd5
gene id: 106582:pdcd5
uniprot id: A0A3P9C4D8
names: Similarity
messages: Belongs to the PDCD5 family.

106582:LOC101471677
gene id: 106582:LOC101471677
uniprot id: A0A3P9BV55
names: Similarity
messages: Belongs to the glutamine synthetase family.

106582:LOC101482593
gene id: 106582:LOC101482593
uniprot id: A0A3P9BEF1
names: Similarity
messages: Belongs to the ARTD/PARP family.

106582:rps23
gene id: 106582:rps23
uniprot id: A0A3P9CGU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

106582:LOC101474409
gene id: 106582:LOC101474409
uniprot id: A0A3P9BN96
names: Similarity
messages: Belongs to the TPRG1 family.

106582:LOC101481904
gene id: 106582:LOC101481904
uniprot id: A0A7D3U2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:atp23
gene id: 106582:atp23
uniprot id: A0A3P9CR93
names: Similarity
messages: Belongs to the peptidase M76 family.

106582:trmt44
gene id: 106582:trmt44
uniprot id: A0A3P9D3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

106582:LOC101481696
gene id: 106582:LOC101481696
uniprot id: A0A3P9BQQ7
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

106582:ptx3
gene id: 106582:ptx3
uniprot id: A0A3P9BXU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ppara
gene id: 106582:ppara
uniprot id: A0A3P9C2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:LOC101479647
gene id: 106582:LOC101479647
uniprot id: A0A3P9CDQ9
names: Similarity
messages: Belongs to the Niban family.

106582:LOC101468166
gene id: 106582:LOC101468166
uniprot id: A0A3P9BVM0
names: Similarity
messages: Belongs to the NAC-beta family.

106582:LOC101469244
gene id: 106582:LOC101469244
uniprot id: A0A3P9CJS3
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101484273
gene id: 106582:LOC101484273
uniprot id: A0A3P9ATR5
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

106582:LOC101481923
gene id: 106582:LOC101481923
uniprot id: A0A3P9BVT1
names: Similarity
messages: Belongs to the BACURD family.

106582:clcc1
gene id: 106582:clcc1
uniprot id: A0A3P9AXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane
messages: Nucleus membrane

106582:gps1
gene id: 106582:gps1
uniprot id: A0A3P9AWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101471901
gene id: 106582:LOC101471901
uniprot id: A0A3P9BSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

106582:ndrg3
gene id: 106582:ndrg3
uniprot id: A0A3P9BTE8
names: Similarity
messages: Belongs to the NDRG family.

106582:LOC101471479
gene id: 106582:LOC101471479
uniprot id: A0A3P9DQA5
names: Similarity
messages: Belongs to the FAM161 family.

106582:polr2c
gene id: 106582:polr2c
uniprot id: A0A3P9CEZ8
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

106582:LOC101480857
gene id: 106582:LOC101480857
uniprot id: A0A3P9BPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

106582:bmpr2
gene id: 106582:bmpr2
uniprot id: A0A3P9ASF6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

106582:LOC101464262
gene id: 106582:LOC101464262
uniprot id: A0A3P9CHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

106582:LOC101483708
gene id: 106582:LOC101483708
uniprot id: A0A3P9DL40
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480423
gene id: 106582:LOC101480423
uniprot id: A0A3P9B0N4
names: Similarity
messages: Belongs to the importin alpha family.

106582:LOC101465244
gene id: 106582:LOC101465244
uniprot id: A0A3P9BEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:LOC101474658
gene id: 106582:LOC101474658
uniprot id: A0A3P9DGS0
names: Similarity
messages: Belongs to the dysbindin family.

106582:LOC101464516
gene id: 106582:LOC101464516
uniprot id: A0A3P9B6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

106582:lsm12
gene id: 106582:lsm12
uniprot id: A0A3P9BC96
names: Similarity
messages: Belongs to the LSM12 family.

106582:tmem258
gene id: 106582:tmem258
uniprot id: A0A3P9ATD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

106582:LOC101487363
gene id: 106582:LOC101487363
uniprot id: A0A3P9DQP7
uniprot id: A0A3P9DR67
uniprot id: A0A3P9DR99
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

106582:LOC101477497
gene id: 106582:LOC101477497
uniprot id: A0A3P9CP93
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101482321
gene id: 106582:LOC101482321
uniprot id: A0A3P9B3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

106582:LOC101470341
gene id: 106582:LOC101470341
uniprot id: A0A3P9DA07
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

106582:LOC101467742
gene id: 106582:LOC101467742
uniprot id: A0A3P9DHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:klhl40
gene id: 106582:klhl40
uniprot id: A0A3P9CWX9
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

106582:LOC101464740
gene id: 106582:LOC101464740
uniprot id: A0A3P9BUM6
uniprot id: A0A3P9BV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

106582:fkbp6
gene id: 106582:fkbp6
uniprot id: A0A3P9C4T8
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

106582:acap2
gene id: 106582:acap2
uniprot id: A0A3P9CNF1
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

106582:LOC101476037
gene id: 106582:LOC101476037
uniprot id: A0A3P9C7Q1
names: Similarity
messages: Belongs to the CD36 family.

106582:LOC101464393
gene id: 106582:LOC101464393
uniprot id: A0A3P9ARU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

106582:LOC101466944
gene id: 106582:LOC101466944
uniprot id: A0A3P9DCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

106582:LOC101475430
gene id: 106582:LOC101475430
uniprot id: A0A3P9CBL4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472576
gene id: 106582:LOC101472576
uniprot id: A0A3P9CCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:LOC101475205
gene id: 106582:LOC101475205
uniprot id: A0A3P9CDP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

106582:cfap300
gene id: 106582:cfap300
uniprot id: A0A3P9BAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

106582:acad9
gene id: 106582:acad9
uniprot id: A0A3P9BHY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106582:map3k13
gene id: 106582:map3k13
uniprot id: A0A3P9BQY2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

106582:LOC101477736
gene id: 106582:LOC101477736
uniprot id: A0A3P9BWY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:slc35a1
gene id: 106582:slc35a1
uniprot id: A0A3P9AZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

106582:LOC101470330
gene id: 106582:LOC101470330
uniprot id: A0A3P9B0Y0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

106582:LOC101486963
gene id: 106582:LOC101486963
uniprot id: A0A3P9BMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:nagk
gene id: 106582:nagk
uniprot id: A0A3P9B6D6
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

106582:LOC101483903
gene id: 106582:LOC101483903
uniprot id: A0A3P9CL04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

106582:LOC101470598
gene id: 106582:LOC101470598
uniprot id: A0A3P9B5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

106582:LOC101468594
gene id: 106582:LOC101468594
uniprot id: A0A3P9B7M0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

106582:pkn1
gene id: 106582:pkn1
uniprot id: A0A3P9ARF0
uniprot id: A0A3P9ARF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

106582:pxmp4
gene id: 106582:pxmp4
uniprot id: A0A3P9B9B6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

106582:pknox2
gene id: 106582:pknox2
uniprot id: A0A3P9DBB8
uniprot id: A0A3P9DCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

106582:cers1
gene id: 106582:cers1
uniprot id: A0A3P9B2X3
names: Subcellular Location Annotation
messages: Membrane

106582:atrn
gene id: 106582:atrn
uniprot id: A0A3P9B368
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pter
gene id: 106582:pter
uniprot id: A0A3P9DFK8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:bsg
gene id: 106582:bsg
uniprot id: A0A3P9BUT7
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane
messages: Membrane

106582:gtpbp1
gene id: 106582:gtpbp1
uniprot id: A0A3P9C2T6
uniprot id: A0A3P9C2U6
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

106582:LOC101477125
gene id: 106582:LOC101477125
uniprot id: A0A3P9CB28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:dvl2
gene id: 106582:dvl2
uniprot id: A0A3P9D481
names: Similarity
messages: Belongs to the DSH family.

106582:LOC101469272
gene id: 106582:LOC101469272
uniprot id: A0A3P9CTH7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:pacs1
gene id: 106582:pacs1
uniprot id: A0A3P9D1A1
names: Similarity
messages: Belongs to the PACS family.

106582:agap2
gene id: 106582:agap2
uniprot id: A0A3P9DLQ9
uniprot id: A0A3P9DMN6
uniprot id: A0A3P9DMN9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

106582:polr2m
gene id: 106582:polr2m
uniprot id: A0A3P9C8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

106582:LOC101477928
gene id: 106582:LOC101477928
uniprot id: A0A3P9B3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

106582:LOC101485391
gene id: 106582:LOC101485391
uniprot id: A0A3P9AYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

106582:ssh1
gene id: 106582:ssh1
uniprot id: A0A3P9CDS1
uniprot id: A0A3P9CEH2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

106582:dpt
gene id: 106582:dpt
uniprot id: A0A3P9BMV1
names: Similarity
messages: Belongs to the dermatopontin family.

106582:LOC101481563
gene id: 106582:LOC101481563
uniprot id: A0A3P9AVW9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:LOC101467661
gene id: 106582:LOC101467661
uniprot id: A0A3P9BRP7
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

106582:LOC101466107
gene id: 106582:LOC101466107
uniprot id: A0A3P9B957
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

106582:sec24c
gene id: 106582:sec24c
uniprot id: A0A3P9B2W0
uniprot id: A0A3P9B2Y1
uniprot id: A0A3P9B3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

106582:LOC101477820
gene id: 106582:LOC101477820
uniprot id: A0A3P9DLP7
uniprot id: A0A3P9DM97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101472185
gene id: 106582:LOC101472185
uniprot id: A0A3P9AWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

106582:vma21
gene id: 106582:vma21
uniprot id: A0A3P9BUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

106582:LOC101485288
gene id: 106582:LOC101485288
uniprot id: A0A3P9DDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:med20
gene id: 106582:med20
uniprot id: A0A3P9BXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:med13
gene id: 106582:med13
uniprot id: A0A3P9D9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:LOC101486428
gene id: 106582:LOC101486428
uniprot id: A0A3P9C923
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

106582:fgf6
gene id: 106582:fgf6
uniprot id: A0A3P9CI87
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101487346
gene id: 106582:LOC101487346
uniprot id: A0A3P9CDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Nucleus
messages: kinetochore

106582:LOC101464253
gene id: 106582:LOC101464253
uniprot id: A0A3P9AR69
uniprot id: A0A3P9AR82
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

106582:slc15a4
gene id: 106582:slc15a4
uniprot id: A0A3P9BP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

106582:LOC101471788
gene id: 106582:LOC101471788
uniprot id: A0A3P9CKT6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:nxph2
gene id: 106582:nxph2
uniprot id: A0A3P9C4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

106582:LOC101475212
gene id: 106582:LOC101475212
uniprot id: A0A3P9AVA5
names: Similarity
messages: Belongs to the MAGUK family.

106582:vps4b
gene id: 106582:vps4b
uniprot id: A0A3P9DHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

106582:cnih1
gene id: 106582:cnih1
uniprot id: A0A3P9BV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

106582:LOC101468642
gene id: 106582:LOC101468642
uniprot id: A0A3P9C4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

106582:fbxo25
gene id: 106582:fbxo25
uniprot id: A0A3P9CL49
uniprot id: A0A3P9CLT5
names: Subcellular Location Annotation
messages: Nucleus

106582:gucy1a1
gene id: 106582:gucy1a1
uniprot id: A0A3P9D7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

106582:sla
gene id: 106582:sla
uniprot id: A0A3P9BFC5
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101464129
gene id: 106582:LOC101464129
uniprot id: A0A3P9BLL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

106582:LOC101466538
gene id: 106582:LOC101466538
uniprot id: A0A3P9DQF8
uniprot id: A0A3P9DRT9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

106582:LOC101479131
gene id: 106582:LOC101479131
uniprot id: A0A3P9DMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

106582:LOC101472334
gene id: 106582:LOC101472334
uniprot id: A0A3P9D0X7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

106582:sh2b3
gene id: 106582:sh2b3
uniprot id: A0A3P9BN23
names: Similarity
messages: Belongs to the SH2B adapter family.

106582:LOC101463885
gene id: 106582:LOC101463885
uniprot id: A0A3P9BNX0
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

106582:tcf25
gene id: 106582:tcf25
uniprot id: A0A3P9C3B2
names: Similarity
messages: Belongs to the TCF25 family.

106582:rpl32
gene id: 106582:rpl32
uniprot id: A0A3P9DC40
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

106582:ndufa2
gene id: 106582:ndufa2
uniprot id: A0A3P9DH22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

106582:pip4p2
gene id: 106582:pip4p2
uniprot id: A0A3P9B6E2
uniprot id: A0A3P9B6F2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

106582:creb3l4
gene id: 106582:creb3l4
uniprot id: A0A3P9CKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:kti12
gene id: 106582:kti12
uniprot id: A0A3P9D722
names: Similarity
messages: Belongs to the KTI12 family.

106582:LOC101469523
gene id: 106582:LOC101469523
uniprot id: A0A3P9BLU5
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

106582:LOC101463657
gene id: 106582:LOC101463657
uniprot id: A0A3P9BAX3
names: Similarity
messages: Belongs to the CDR2 family.

106582:LOC101464735
gene id: 106582:LOC101464735
uniprot id: A0A3P9BXN7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:zfp36l1
gene id: 106582:zfp36l1
uniprot id: A0A3P9CC15
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

106582:LOC101481005
gene id: 106582:LOC101481005
uniprot id: A0A3P9CHR4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

106582:aldh5a1
gene id: 106582:aldh5a1
uniprot id: A0A3P9CKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

106582:ing5
gene id: 106582:ing5
uniprot id: A0A3P9CWL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

106582:LOC101474805
gene id: 106582:LOC101474805
uniprot id: A0A3P9AWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

106582:ctnna1
gene id: 106582:ctnna1
uniprot id: A0A3P9BQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

106582:pias4
gene id: 106582:pias4
uniprot id: A0A3P9BG43
names: Similarity
messages: Belongs to the PIAS family.

106582:LOC101466399
gene id: 106582:LOC101466399
uniprot id: A0A3P9C7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:pfdn6
gene id: 106582:pfdn6
uniprot id: A0A3P9BEJ7
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

106582:LOC101474257
gene id: 106582:LOC101474257
uniprot id: A0A3P9C696
names: Subcellular Location Annotation
messages: ruffle membrane

106582:LOC101465714
gene id: 106582:LOC101465714
uniprot id: A0A3P9C2G2
names: Similarity
messages: Belongs to the NifU family.

106582:atic
gene id: 106582:atic
uniprot id: A0A3P9BCM6
names: Similarity
messages: Belongs to the PurH family.

106582:LOC101484664
gene id: 106582:LOC101484664
uniprot id: A0A3P9BS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

106582:LOC101478763
gene id: 106582:LOC101478763
uniprot id: A0A3P9CDT7
uniprot id: A0A3P9CE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

106582:tspan31
gene id: 106582:tspan31
uniprot id: A0A3P9DLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101471902
gene id: 106582:LOC101471902
uniprot id: A0A3P9BW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

106582:LOC101479192
gene id: 106582:LOC101479192
uniprot id: A0A3P9CH43
names: Similarity
messages: Belongs to the LCA5 family.

106582:LOC101473872
gene id: 106582:LOC101473872
uniprot id: A0A3P9B6X9
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

106582:LOC101468784
gene id: 106582:LOC101468784
uniprot id: A0A3P9CTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:slit1
gene id: 106582:slit1
uniprot id: A0A3P9ARP0
uniprot id: A0A3P9ARZ9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101479751
gene id: 106582:LOC101479751
uniprot id: A0A3P9CMR8
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

106582:LOC101473431
gene id: 106582:LOC101473431
uniprot id: A0A3P9CXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

106582:creg2
gene id: 106582:creg2
uniprot id: A0A3P9D6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

106582:LOC101482041
gene id: 106582:LOC101482041
uniprot id: A0A3P9DMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

106582:LOC101487116
gene id: 106582:LOC101487116
uniprot id: A0A3P9CGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101472205
gene id: 106582:LOC101472205
uniprot id: A0A3P9BEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

106582:zdhhc7
gene id: 106582:zdhhc7
uniprot id: A0A3P9BSG9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:kyat3
gene id: 106582:kyat3
uniprot id: A0A3P9BSL3
names: Subunit
messages: Homodimer.

106582:ankrd13d
gene id: 106582:ankrd13d
uniprot id: A0A3P9B3T9
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

106582:tasp1
gene id: 106582:tasp1
uniprot id: A0A3P9BRD5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

106582:LOC101483007
gene id: 106582:LOC101483007
uniprot id: A0A3P9DR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:nadk
gene id: 106582:nadk
uniprot id: A0A3P9D3F9
names: Similarity
messages: Belongs to the NAD kinase family.

106582:gfm2
gene id: 106582:gfm2
uniprot id: A0A3P9B7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

106582:zfyve27
gene id: 106582:zfyve27
uniprot id: A0A3P9BH10
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

106582:LOC101475904
gene id: 106582:LOC101475904
uniprot id: A0A3P9B0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

106582:LOC101464077
gene id: 106582:LOC101464077
uniprot id: A0A3P9B8I1
names: Similarity
messages: Belongs to the peptidase C14A family.

106582:gng2
gene id: 106582:gng2
uniprot id: A0A3P9C2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:zmpste24
gene id: 106582:zmpste24
uniprot id: A0A3P9B9A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

106582:ssbp2
gene id: 106582:ssbp2
uniprot id: A0A3P9CC38
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101467453
gene id: 106582:LOC101467453
uniprot id: A0A3P9BLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:dlk1
gene id: 106582:dlk1
uniprot id: A0A3P9B8T9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101479531
gene id: 106582:LOC101479531
uniprot id: A0A3P9CDD9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:vps28
gene id: 106582:vps28
uniprot id: A0A3P9B7A0
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

106582:LOC101476810
gene id: 106582:LOC101476810
uniprot id: A0A3P9CUR4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:LOC101475585
gene id: 106582:LOC101475585
uniprot id: A0A3P9AQZ7
names: Similarity
messages: Belongs to the DNase II family.

106582:LOC101465984
gene id: 106582:LOC101465984
uniprot id: A0A3P9DD30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

106582:LOC101477921
gene id: 106582:LOC101477921
uniprot id: A0A3P9CX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

106582:LOC101468589
gene id: 106582:LOC101468589
uniprot id: A0A3P9B0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

106582:LOC101476081
gene id: 106582:LOC101476081
uniprot id: A0A3P9B6S0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:adcy6
gene id: 106582:adcy6
uniprot id: A0A3P9DL47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

106582:abracl
gene id: 106582:abracl
uniprot id: A0A3P9B6V0
names: Similarity
messages: Belongs to the costars family.

106582:LOC101479010
gene id: 106582:LOC101479010
uniprot id: A0A3P9B5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:p2rx2
gene id: 106582:p2rx2
uniprot id: A0A3P9CI86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

106582:LOC101469691
gene id: 106582:LOC101469691
uniprot id: A0A3P9CCL8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:ptprn2
gene id: 106582:ptprn2
uniprot id: A0A3P9AT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

106582:maml3
gene id: 106582:maml3
uniprot id: A0A3P9BZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

106582:LOC101474157
gene id: 106582:LOC101474157
uniprot id: A0A3P9D2T1
names: Similarity
messages: Belongs to the cornifelin family.

106582:LOC101482157
gene id: 106582:LOC101482157
uniprot id: A0A3P9C456
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472976
gene id: 106582:LOC101472976
uniprot id: A0A3P9BMS5
names: Subcellular Location Annotation
messages: Nucleus

106582:ccdc86
gene id: 106582:ccdc86
uniprot id: A0A3P9CXN0
names: Subcellular Location Annotation
messages: Nucleus

106582:lcmt1
gene id: 106582:lcmt1
uniprot id: A0A3P9BJ73
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

106582:LOC101479080
gene id: 106582:LOC101479080
uniprot id: A0A3P9DNN9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101464165
gene id: 106582:LOC101464165
uniprot id: A0A3P9AXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101484359
gene id: 106582:LOC101484359
uniprot id: A0A3P9ASF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

106582:ftcd
gene id: 106582:ftcd
uniprot id: A0A3P9C7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

106582:LOC101474911
gene id: 106582:LOC101474911
uniprot id: A0A3P9BG08
names: Subcellular Location Annotation
messages: Membrane

106582:rad50
gene id: 106582:rad50
uniprot id: A0A3P9B013
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

106582:LOC101468688
gene id: 106582:LOC101468688
uniprot id: A0A3P9C5K1
names: Similarity
messages: Belongs to the peptidase M10A family.

106582:LOC101478719
gene id: 106582:LOC101478719
uniprot id: A0A3P9BF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

106582:carm1
gene id: 106582:carm1
uniprot id: A0A3P9AS37
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484138
gene id: 106582:LOC101484138
uniprot id: A0A3P9CVZ0
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

106582:LOC101476967
gene id: 106582:LOC101476967
uniprot id: A0A3P9DE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:polg2
gene id: 106582:polg2
uniprot id: A0A3P9AVP3
names: Subcellular Location Annotation
messages: Mitochondrion

106582:LOC101482061
gene id: 106582:LOC101482061
uniprot id: A0A3P9BDU0
uniprot id: A0A3P9BE39
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

106582:mocs2
gene id: 106582:mocs2
uniprot id: A0A3P9D9D0
uniprot id: A0A3P9DAZ0
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).
messages: cytosol

106582:slc2a4
gene id: 106582:slc2a4
uniprot id: A0A3P9D3A5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:prkd3
gene id: 106582:prkd3
uniprot id: A0A3P9C5S3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

106582:LOC101477702
gene id: 106582:LOC101477702
uniprot id: A0A3P9DGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:nr4a2
gene id: 106582:nr4a2
uniprot id: A0A3P9BLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101483958
gene id: 106582:LOC101483958
uniprot id: A0A3P9C0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

106582:wdr46
gene id: 106582:wdr46
uniprot id: A0A3P9AQV4
names: Subcellular Location Annotation
messages: nucleolus

106582:cebpa
gene id: 106582:cebpa
uniprot id: A0A3P9AXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

106582:ddx20
gene id: 106582:ddx20
uniprot id: A0A3P9DNC7
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:LOC101473618
gene id: 106582:LOC101473618
uniprot id: A0A3P9BEA2
names: Subcellular Location Annotation
messages: Nucleus

106582:mrrf
gene id: 106582:mrrf
uniprot id: A0A3P9CPB9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

106582:pgr
gene id: 106582:pgr
uniprot id: A0A3P9DDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:slc25a29
gene id: 106582:slc25a29
uniprot id: A0A3P9B864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101480156
gene id: 106582:LOC101480156
uniprot id: A0A3P9BT50
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

106582:LOC101475676
gene id: 106582:LOC101475676
uniprot id: A0A3P9DQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101472990
gene id: 106582:LOC101472990
uniprot id: A0A3P9BE35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

106582:LOC101468176
gene id: 106582:LOC101468176
uniprot id: A0A3P9DSD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:LOC101464213
gene id: 106582:LOC101464213
uniprot id: A0A3P9CFU3
uniprot id: A0A3P9CG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

106582:tspan12
gene id: 106582:tspan12
uniprot id: A0A3P9CQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101476914
gene id: 106582:LOC101476914
uniprot id: A0A3P9BS76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

106582:LOC101487638
gene id: 106582:LOC101487638
uniprot id: A0A3P9BQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:LOC101484884
gene id: 106582:LOC101484884
uniprot id: A0A3P9B7A6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.

106582:hmgn3
gene id: 106582:hmgn3
uniprot id: A0A3P9BVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

106582:pdcd4
gene id: 106582:pdcd4
uniprot id: A0A3P9B1U8
names: Similarity
messages: Belongs to the PDCD4 family.

106582:LOC101464222
gene id: 106582:LOC101464222
uniprot id: A0A3P9CTS9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

106582:faxc
gene id: 106582:faxc
uniprot id: A0A3P9C183
names: Similarity
messages: Belongs to the FAX family.

106582:APK84 gp01
gene id: 106582:APK84_gp01
uniprot id: A0A0K2CIW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

106582:bves
gene id: 106582:bves
uniprot id: A0A3P9DGF1
names: Similarity
messages: Belongs to the popeye family.

106582:LOC101464789
gene id: 106582:LOC101464789
uniprot id: A0A3P9DC91
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:tardbp
gene id: 106582:tardbp
uniprot id: A0A3P9C771
names: Subcellular Location Annotation
messages: Nucleus

106582:scn3b
gene id: 106582:scn3b
uniprot id: A0A3P9CG21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

106582:sod1
gene id: 106582:sod1
uniprot id: A0A3P9DDW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

106582:mrpl11
gene id: 106582:mrpl11
uniprot id: A0A3P9BBA8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

106582:tubgcp6
gene id: 106582:tubgcp6
uniprot id: A0A3P9BQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

106582:sema3a
gene id: 106582:sema3a
uniprot id: A0A3P9CXE3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:nup210
gene id: 106582:nup210
uniprot id: A0A3P9DIR2
uniprot id: A0A3P9DKF2
names: Similarity
messages: Belongs to the NUP210 family.

106582:LOC101481750
gene id: 106582:LOC101481750
uniprot id: A0A3P9B3W3
uniprot id: A0A3P9B3X9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

106582:pde11a
gene id: 106582:pde11a
uniprot id: A0A3P9B7P9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:imp3
gene id: 106582:imp3
uniprot id: A0A3P9BBE6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

106582:LOC101477113
gene id: 106582:LOC101477113
uniprot id: A0A3P9BAZ2
uniprot id: A0A3P9BB82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:csrnp3
gene id: 106582:csrnp3
uniprot id: A0A3P9BF74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

106582:LOC101467473
gene id: 106582:LOC101467473
uniprot id: A0A3P9CML9
names: Similarity
messages: Belongs to the ATG8 family.

106582:rarg
gene id: 106582:rarg
uniprot id: A0A3P9DNS4
uniprot id: A0A3P9DQL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

106582:yars2
gene id: 106582:yars2
uniprot id: A0A3P9BU67
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:mapk6
gene id: 106582:mapk6
uniprot id: A0A3P9BHF9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

106582:galr2
gene id: 106582:galr2
uniprot id: A0A3P9BT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:LOC101482978
gene id: 106582:LOC101482978
uniprot id: A0A3P9C0L7
names: Similarity
messages: Belongs to the TAFA family.

106582:LOC101480459
gene id: 106582:LOC101480459
uniprot id: A0A3P9CIT1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101466283
gene id: 106582:LOC101466283
uniprot id: A0A3P9BVS0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101481335
gene id: 106582:LOC101481335
uniprot id: A0A3P9DKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:LOC101482107
gene id: 106582:LOC101482107
uniprot id: A0A3P9BEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101475240
gene id: 106582:LOC101475240
uniprot id: A0A3P9CM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

106582:wdr45
gene id: 106582:wdr45
uniprot id: A0A3P9C056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure

106582:tac1
gene id: 106582:tac1
uniprot id: A0A3P9CP51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

106582:dhh
gene id: 106582:dhh
uniprot id: A0A3P9DQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

106582:wisp1
gene id: 106582:wisp1
uniprot id: A0A3P9BFE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:mfsd3
gene id: 106582:mfsd3
uniprot id: A0A3P9BVY9
names: Subcellular Location Annotation
messages: Membrane

106582:elavl3
gene id: 106582:elavl3
uniprot id: A0A3P9CT52
names: Similarity
messages: Belongs to the RRM elav family.

106582:napg
gene id: 106582:napg
uniprot id: A0A3P9DE41
names: Similarity
messages: Belongs to the SNAP family.

106582:LOC101467861
gene id: 106582:LOC101467861
uniprot id: A0A3P9BBU0
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

106582:uros
gene id: 106582:uros
uniprot id: A0A3P9AX17
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

106582:smoc1
gene id: 106582:smoc1
uniprot id: A0A3P9BZV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:mrpl18
gene id: 106582:mrpl18
uniprot id: A0A3P9C6C5
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

106582:rpl17
gene id: 106582:rpl17
uniprot id: A0A3P9DA45
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

106582:LOC101469686
gene id: 106582:LOC101469686
uniprot id: A0A3P9C2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

106582:ap1m1
gene id: 106582:ap1m1
uniprot id: A0A3P9DEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

106582:LOC101476567
gene id: 106582:LOC101476567
uniprot id: A0A3P9B8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

106582:rnmt
gene id: 106582:rnmt
uniprot id: A0A3P9C2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

106582:LOC101471562
gene id: 106582:LOC101471562
uniprot id: A0A3P9DSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

106582:spdl1
gene id: 106582:spdl1
uniprot id: A0A3P9CP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

106582:LOC101482885
gene id: 106582:LOC101482885
uniprot id: A0A3P9B023
names: Subcellular Location Annotation
messages: Membrane

106582:inpp5a
gene id: 106582:inpp5a
uniprot id: A0A3P9CPV5
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

106582:LOC101466242
gene id: 106582:LOC101466242
uniprot id: A0A3P9BWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

106582:pop5
gene id: 106582:pop5
uniprot id: A0A3P9AQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

106582:ficd
gene id: 106582:ficd
uniprot id: A0A3P9CDV4
names: Similarity
messages: Belongs to the fic family.

106582:bicd1
gene id: 106582:bicd1
uniprot id: A0A3P9CJD5
uniprot id: A0A3P9CJW2
names: Similarity
messages: Belongs to the BicD family.

106582:APK84 gp09
gene id: 106582:APK84_gp09
uniprot id: A0A0K2CJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

106582:tmem150a
gene id: 106582:tmem150a
uniprot id: A0A3P9CT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

106582:cept1
gene id: 106582:cept1
uniprot id: A0A3P9CMA3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

106582:LOC101474470
gene id: 106582:LOC101474470
uniprot id: A0A3P9BBB7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:gfra1
gene id: 106582:gfra1
uniprot id: A0A3P9DQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

106582:LOC101464693
gene id: 106582:LOC101464693
uniprot id: A0A3P9ATA9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

106582:LOC101464464
gene id: 106582:LOC101464464
uniprot id: A0A3P9CIF3
names: Similarity
messages: Belongs to the peptidase C14A family.

106582:LOC101476161
gene id: 106582:LOC101476161
uniprot id: A0A3P9C888
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:tmem43
gene id: 106582:tmem43
uniprot id: A0A3P9C155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

106582:lamp5
gene id: 106582:lamp5
uniprot id: A0A3P9BXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

106582:nhsl1
gene id: 106582:nhsl1
uniprot id: A0A3P9CKX4
uniprot id: A0A3P9CLI9
names: Similarity
messages: Belongs to the NHS family.

106582:LOC101470618
gene id: 106582:LOC101470618
uniprot id: A0A3P9BJ88
uniprot id: A0A3P9BJA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

106582:nelfe
gene id: 106582:nelfe
uniprot id: A0A3P9DKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

106582:LOC101481630
gene id: 106582:LOC101481630
uniprot id: A0A3P9DN33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

106582:LOC101479813
gene id: 106582:LOC101479813
uniprot id: A0A3P9DQM6
uniprot id: A0A3P9DR47
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

106582:tmem136
gene id: 106582:tmem136
uniprot id: A0A3P9CFR6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486923
gene id: 106582:LOC101486923
uniprot id: A0A3P9BHE4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:cep19
gene id: 106582:cep19
uniprot id: A0A3P9CWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

106582:tctn3
gene id: 106582:tctn3
uniprot id: A0A3P9C8A0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

106582:LOC101487581
gene id: 106582:LOC101487581
uniprot id: A0A3P9BVW3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

106582:LOC101470535
gene id: 106582:LOC101470535
uniprot id: A0A3P9DB04
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.

106582:rnf7
gene id: 106582:rnf7
uniprot id: A0A3P9BLZ3
names: Similarity
messages: Belongs to the RING-box family.

106582:uba2
gene id: 106582:uba2
uniprot id: A0A3P9BTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

106582:rngtt
gene id: 106582:rngtt
uniprot id: A0A3P9AZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

106582:LOC101463845
gene id: 106582:LOC101463845
uniprot id: A0A3P9CZ29
names: Similarity
messages: Belongs to the peptidase M67C family.

106582:slc35c1
gene id: 106582:slc35c1
uniprot id: A0A3P9CAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

106582:snrpd3
gene id: 106582:snrpd3
uniprot id: A0A3P9CMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

106582:LOC101474726
gene id: 106582:LOC101474726
uniprot id: A0A3P9BRU9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

106582:LOC101464193
gene id: 106582:LOC101464193
uniprot id: A0A3P9B8P2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101467542
gene id: 106582:LOC101467542
uniprot id: A0A3P9DD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:ppp2cb
gene id: 106582:ppp2cb
uniprot id: A0A3P9AXM0
names: Similarity
messages: Belongs to the PPP phosphatase family.

106582:LOC101473927
gene id: 106582:LOC101473927
uniprot id: A0A3P9CXF3
names: Similarity
messages: Belongs to the CKAP2 family.

106582:trmt11
gene id: 106582:trmt11
uniprot id: A0A3P9AXT2
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

106582:LOC101468538
gene id: 106582:LOC101468538
uniprot id: A0A3P9DGC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101478303
gene id: 106582:LOC101478303
uniprot id: A0A3P9BJV9
names: Similarity
messages: Belongs to the ZC3H12 family.

106582:stoml1
gene id: 106582:stoml1
uniprot id: A0A3P9D7E0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

106582:LOC101468677
gene id: 106582:LOC101468677
uniprot id: A0A3P9CRH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

106582:slc25a51
gene id: 106582:slc25a51
uniprot id: A0A3P9C761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101482895
gene id: 106582:LOC101482895
uniprot id: A0A3P9B485
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:slc25a53
gene id: 106582:slc25a53
uniprot id: A0A3P9BZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101484380
gene id: 106582:LOC101484380
uniprot id: A0A3P9D9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

106582:mb
gene id: 106582:mb
uniprot id: A0A3P9DC87
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

106582:pnmt
gene id: 106582:pnmt
uniprot id: A0A3P9CG54
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

106582:exosc3
gene id: 106582:exosc3
uniprot id: A0A3P9BHK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

106582:mboat7
gene id: 106582:mboat7
uniprot id: A0A3P9CJ11
names: Subcellular Location Annotation
messages: Membrane

106582:arsg
gene id: 106582:arsg
uniprot id: A0A3P9BQR6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

106582:LOC101464589
gene id: 106582:LOC101464589
uniprot id: A0A3P9DKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

106582:st6galnac5
gene id: 106582:st6galnac5
uniprot id: A0A3P9DDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:LOC101465716
gene id: 106582:LOC101465716
uniprot id: A0A3P9BSY8
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

106582:pld4
gene id: 106582:pld4
uniprot id: A0A3P9DP41
names: Similarity
messages: Belongs to the phospholipase D family.

106582:LOC101486419
gene id: 106582:LOC101486419
uniprot id: A0A3P9BFR4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:LOC101471398
gene id: 106582:LOC101471398
uniprot id: A0A3P9C9X0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101479529
gene id: 106582:LOC101479529
uniprot id: A0A3P9C1A8
uniprot id: A0A3P9C1C1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101485649
gene id: 106582:LOC101485649
uniprot id: A0A3P9DHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

106582:eef2
gene id: 106582:eef2
uniprot id: A0A3P9DJB7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

106582:LOC101477176
gene id: 106582:LOC101477176
uniprot id: A0A3P9CRV2
uniprot id: A0A3P9CTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

106582:LOC101487146
gene id: 106582:LOC101487146
uniprot id: A0A3P9BRF6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

106582:LOC101477635
gene id: 106582:LOC101477635
uniprot id: A0A3P9CRA2
names: Subcellular Location Annotation
messages: Nucleus

106582:camk4
gene id: 106582:camk4
uniprot id: A0A3P9B2V4
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:mindy2
gene id: 106582:mindy2
uniprot id: A0A3P9C823
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

106582:cnot9
gene id: 106582:cnot9
uniprot id: A0A3P9CA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

106582:LOC101477448
gene id: 106582:LOC101477448
uniprot id: A0A3P9BBT0
uniprot id: A0A3P9BC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

106582:ssr2
gene id: 106582:ssr2
uniprot id: A0A3P9CP83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

106582:LOC101483025
gene id: 106582:LOC101483025
uniprot id: A0A3P9CWZ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101472751
gene id: 106582:LOC101472751
uniprot id: A0A3P9DG05
names: Similarity
messages: Belongs to the serpin family.

106582:bok
gene id: 106582:bok
uniprot id: A0A3P9BSD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

106582:glod4
gene id: 106582:glod4
uniprot id: A0A3P9BKH8
names: Similarity
messages: Belongs to the glyoxalase I family.

106582:LOC101480522
gene id: 106582:LOC101480522
uniprot id: A0A3P9BNF9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

106582:LOC101474609
gene id: 106582:LOC101474609
uniprot id: A0A3P9DAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

106582:LOC101477929
gene id: 106582:LOC101477929
uniprot id: A0A3P9CF87
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:cfap97
gene id: 106582:cfap97
uniprot id: A0A3P9D801
names: Similarity
messages: Belongs to the CFAP97 family.

106582:cdc37l1
gene id: 106582:cdc37l1
uniprot id: A0A3P9CMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

106582:ism1
gene id: 106582:ism1
uniprot id: A0A3P9BQJ1
names: Similarity
messages: Belongs to the isthmin family.

106582:pdgfra
gene id: 106582:pdgfra
uniprot id: A0A3P9CYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101480162
gene id: 106582:LOC101480162
uniprot id: A0A3P9CHJ6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:postn
gene id: 106582:postn
uniprot id: A0A3P9DDH4
uniprot id: A0A3P9DF11
names: Subcellular Location Annotation
messages: extracellular matrix

106582:ptprg
gene id: 106582:ptprg
uniprot id: A0A3P9CFN4
uniprot id: A0A3P9CGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

106582:LOC101471033
gene id: 106582:LOC101471033
uniprot id: A0A3P9CJI3
names: Similarity
messages: Belongs to the SH3BGR family.

106582:LOC101482156
gene id: 106582:LOC101482156
uniprot id: A0A3P9C535
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

106582:LOC101468523
gene id: 106582:LOC101468523
uniprot id: A0A3P9C149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:nadk2
gene id: 106582:nadk2
uniprot id: A0A3P9BXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

106582:slc29a4
gene id: 106582:slc29a4
uniprot id: A0A3P9BJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

106582:lhfpl6
gene id: 106582:lhfpl6
uniprot id: A0A3P9DCG5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101475717
gene id: 106582:LOC101475717
uniprot id: A0A3P9CMT8
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

106582:pex16
gene id: 106582:pex16
uniprot id: A0A3P9CJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

106582:LOC101477914
gene id: 106582:LOC101477914
uniprot id: A0A3P9BQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Chromosome

106582:nprl3
gene id: 106582:nprl3
uniprot id: A0A3P9D4T7
uniprot id: A0A3P9D521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

106582:LOC101477589
gene id: 106582:LOC101477589
uniprot id: A0A3P9AYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

106582:LOC101481375
gene id: 106582:LOC101481375
uniprot id: A0A3P9BL91
names: Similarity
messages: Belongs to the PP2C family.

106582:dazap2
gene id: 106582:dazap2
uniprot id: A0A3P9DME6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

106582:trmt61a
gene id: 106582:trmt61a
uniprot id: A0A3P9AXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

106582:LOC101477280
gene id: 106582:LOC101477280
uniprot id: A0A3P9DAI9
names: Similarity
messages: Belongs to the WD repeat coronin family.

106582:reep5
gene id: 106582:reep5
uniprot id: A0A3P9BY25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

106582:mrpl40
gene id: 106582:mrpl40
uniprot id: A0A3P9BT95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

106582:LOC101474026
gene id: 106582:LOC101474026
uniprot id: A0A3P9B3P1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

106582:LOC101466371
gene id: 106582:LOC101466371
uniprot id: A0A3P9CC09
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

106582:cnih4
gene id: 106582:cnih4
uniprot id: A0A3P9DG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

106582:LOC101464265
gene id: 106582:LOC101464265
uniprot id: A0A3P9DMC0
names: Similarity
messages: Belongs to the actin family.

106582:vax2
gene id: 106582:vax2
uniprot id: A0A3P9D177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

106582:LOC101475580
gene id: 106582:LOC101475580
uniprot id: A0A3P9D141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101487550
gene id: 106582:LOC101487550
uniprot id: A0A3P9BYR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:ssx2ip
gene id: 106582:ssx2ip
uniprot id: A0A3P9DEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

106582:LOC101466428
gene id: 106582:LOC101466428
uniprot id: A0A3P9BBG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ranbp10
gene id: 106582:ranbp10
uniprot id: A0A3P9BVF6
names: Similarity
messages: Belongs to the RANBP9/10 family.

106582:LOC101478722
gene id: 106582:LOC101478722
uniprot id: A0A3P9CJR5
names: Similarity
messages: Belongs to the requiem/DPF family.

106582:mtx3
gene id: 106582:mtx3
uniprot id: A0A3P9CKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:hm13
gene id: 106582:hm13
uniprot id: A0A3P9DNX4
uniprot id: A0A3P9DP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

106582:LOC101480896
gene id: 106582:LOC101480896
uniprot id: A0A3P9BF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

106582:dnaaf2
gene id: 106582:dnaaf2
uniprot id: A0A3P9BF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

106582:LOC101478436
gene id: 106582:LOC101478436
uniprot id: A0A3P9CZC1
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

106582:sec13
gene id: 106582:sec13
uniprot id: A0A3P9BK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

106582:LOC101469458
gene id: 106582:LOC101469458
uniprot id: A0A3P9BUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:ahcy
gene id: 106582:ahcy
uniprot id: A0A3P9CJS8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

106582:LOC101469767
gene id: 106582:LOC101469767
uniprot id: A0A3P9CA31
names: Subcellular Location Annotation
messages: Nucleus

106582:elk3
gene id: 106582:elk3
uniprot id: A0A3P9BG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101488089
gene id: 106582:LOC101488089
uniprot id: A0A3P9DPM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pik3ip1
gene id: 106582:pik3ip1
uniprot id: A0A3P9CM31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101468280
gene id: 106582:LOC101468280
uniprot id: A0A3P9DKY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

106582:msx1
gene id: 106582:msx1
uniprot id: A0A3P9DPM1
names: Subcellular Location Annotation
messages: Nucleus

106582:eif3b
gene id: 106582:eif3b
uniprot id: A0A3P9C0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

106582:tmco1
gene id: 106582:tmco1
uniprot id: A0A3P9BWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:atp6v0e1
gene id: 106582:atp6v0e1
uniprot id: A0A3P9BPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

106582:eif6
gene id: 106582:eif6
uniprot id: A0A3P9BQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

106582:psma1
gene id: 106582:psma1
uniprot id: A0A3P9C310
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:LOC101469930
gene id: 106582:LOC101469930
uniprot id: A0A3P9D4Z6
names: Similarity
messages: Belongs to the IUNH family.

106582:rnaseh1
gene id: 106582:rnaseh1
uniprot id: A0A3P9C5K0
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

106582:LOC101464004
gene id: 106582:LOC101464004
uniprot id: A0A3P9B1T8
uniprot id: A0A3P9B1Z6
uniprot id: A0A3P9B224
uniprot id: A0A3P9B2H5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

106582:LOC101470180
gene id: 106582:LOC101470180
uniprot id: A0A3P9ASQ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:clp1
gene id: 106582:clp1
uniprot id: A0A3P9B177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

106582:mms22l
gene id: 106582:mms22l
uniprot id: A0A3P9C192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

106582:cplx4
gene id: 106582:cplx4
uniprot id: A0A3P9CWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

106582:grb2
gene id: 106582:grb2
uniprot id: A0A3P9B754
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

106582:ugcg
gene id: 106582:ugcg
uniprot id: A0A3P9DB24
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

106582:ebag9
gene id: 106582:ebag9
uniprot id: A0A3P9BZV8
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

106582:LOC101486274
gene id: 106582:LOC101486274
uniprot id: A0A3P9CMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

106582:aoc1
gene id: 106582:aoc1
uniprot id: A0A3P9CEE4
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

106582:rax
gene id: 106582:rax
uniprot id: A0A3P9CWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

106582:LOC101473239
gene id: 106582:LOC101473239
uniprot id: A0A3P9BX08
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

106582:clrn3
gene id: 106582:clrn3
uniprot id: A0A3P9AYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

106582:hspa13
gene id: 106582:hspa13
uniprot id: A0A3P9C815
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

106582:smc3
gene id: 106582:smc3
uniprot id: A0A3P9B2B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

106582:LOC101473404
gene id: 106582:LOC101473404
uniprot id: A0A3P9CS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

106582:LOC101484912
gene id: 106582:LOC101484912
uniprot id: A0A3P9BC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

106582:LOC101478017
gene id: 106582:LOC101478017
uniprot id: A0A3P9CBA9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

106582:LOC101466766
gene id: 106582:LOC101466766
uniprot id: A0A3P9C388
uniprot id: A0A3P9C3K4
uniprot id: A0A3P9C3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

106582:LOC101486046
gene id: 106582:LOC101486046
uniprot id: A0A3P9BXD9
names: Similarity
messages: Belongs to the dapper family.

106582:LOC101475415
gene id: 106582:LOC101475415
uniprot id: A0A3P9C0H9
names: Similarity
messages: Belongs to the FAM83 family.

106582:LOC101476815
gene id: 106582:LOC101476815
uniprot id: A0A3P9BF62
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101467153
gene id: 106582:LOC101467153
uniprot id: A0A3P9BGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101466923
gene id: 106582:LOC101466923
uniprot id: A0A3P9BJC1
names: Subcellular Location Annotation
messages: Nucleus

106582:fam131a
gene id: 106582:fam131a
uniprot id: A0A3P9B4C2
names: Similarity
messages: Belongs to the FAM131 family.

106582:mapk4
gene id: 106582:mapk4
uniprot id: A0A3P9BCE2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

106582:LOC101464180
gene id: 106582:LOC101464180
uniprot id: A0A3P9C505
uniprot id: A0A3P9C5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

106582:lhx8
gene id: 106582:lhx8
uniprot id: A0A3P9BER9
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482683
gene id: 106582:LOC101482683
uniprot id: A0A3P9BJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:vwc2
gene id: 106582:vwc2
uniprot id: A0A3P9C0F1
names: Subcellular Location Annotation
messages: Synapse

106582:rftn2
gene id: 106582:rftn2
uniprot id: A0A3P9D2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

106582:pqlc3
gene id: 106582:pqlc3
uniprot id: A0A3P9BQ09
names: Subcellular Location Annotation
messages: Membrane

106582:capn3
gene id: 106582:capn3
uniprot id: A0A3P9C0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

106582:parg
gene id: 106582:parg
uniprot id: A0A3P9DS32
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

106582:rnf2
gene id: 106582:rnf2
uniprot id: A0A3P9CFG7
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

106582:asic1
gene id: 106582:asic1
uniprot id: A0A3P9B6L9
uniprot id: A0A3P9B6P0
uniprot id: A0A3P9B6V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101482159
gene id: 106582:LOC101482159
uniprot id: A0A3P9CHI1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:tp53inp2
gene id: 106582:tp53inp2
uniprot id: A0A3P9DN21
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

106582:LOC101470786
gene id: 106582:LOC101470786
uniprot id: A0A3P9BW36
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101475673
gene id: 106582:LOC101475673
uniprot id: A0A3P9C8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

106582:polr3a
gene id: 106582:polr3a
uniprot id: A0A3P9AT44
uniprot id: A0A3P9ATS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

106582:arglu1
gene id: 106582:arglu1
uniprot id: A0A3P9C5G8
names: Similarity
messages: Belongs to the UPF0430 family.

106582:gab2
gene id: 106582:gab2
uniprot id: A0A3P9DDR3
names: Similarity
messages: Belongs to the GAB family.

106582:LOC101477071
gene id: 106582:LOC101477071
uniprot id: A0A3P9BFG4
uniprot id: A0A3P9BFK4
names: Similarity
messages: Belongs to the NDRG family.

106582:dnajb12
gene id: 106582:dnajb12
uniprot id: A0A3P9AV51
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479682
gene id: 106582:LOC101479682
uniprot id: A0A3P9BN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

106582:ndc1
gene id: 106582:ndc1
uniprot id: A0A3P9DEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

106582:bet1l
gene id: 106582:bet1l
uniprot id: A0A3P9D6G0
names: Subcellular Location Annotation
messages: Membrane

106582:snx33
gene id: 106582:snx33
uniprot id: A0A3P9BWV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

106582:kdm1a
gene id: 106582:kdm1a
uniprot id: A0A3P9B3X1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

106582:LOC101481892
gene id: 106582:LOC101481892
uniprot id: A0A3P9BEI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

106582:cd55
gene id: 106582:cd55
uniprot id: A0A3P9AXG4
uniprot id: A0A3P9AXH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101465598
gene id: 106582:LOC101465598
uniprot id: A0A3P9C3Z3
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101469939
gene id: 106582:LOC101469939
uniprot id: A0A3P9B9N0
names: Similarity
messages: Belongs to the MAGUK family.

106582:abraxas2
gene id: 106582:abraxas2
uniprot id: A0A3P9DRH3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101479976
gene id: 106582:LOC101479976
uniprot id: A0A3P9B2C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101486085
gene id: 106582:LOC101486085
uniprot id: A0A3P9BYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

106582:pkp4
gene id: 106582:pkp4
uniprot id: A0A3P9BQ90
names: Similarity
messages: Belongs to the beta-catenin family.

106582:lhcgr
gene id: 106582:lhcgr
uniprot id: A0A3P9BEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

106582:baz1b
gene id: 106582:baz1b
uniprot id: A0A3P9BLD4
names: Subcellular Location Annotation
messages: Nucleus

106582:chst14
gene id: 106582:chst14
uniprot id: A0A3P9CXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:bola3
gene id: 106582:bola3
uniprot id: A0A3P9CB83
names: Similarity
messages: Belongs to the BolA/IbaG family.

106582:LOC101480204
gene id: 106582:LOC101480204
uniprot id: A0A3P9CXE7
names: Subcellular Location Annotation
messages: Membrane

106582:bicc1
gene id: 106582:bicc1
uniprot id: A0A3P9DPW7
names: Similarity
messages: Belongs to the BicC family.

106582:raf1
gene id: 106582:raf1
uniprot id: A0A3P9DJX3
uniprot id: A0A3P9DKF7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

106582:LOC101478297
gene id: 106582:LOC101478297
uniprot id: A0A3P9B378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

106582:b3galnt2
gene id: 106582:b3galnt2
uniprot id: A0A3P9BTA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:tmem47
gene id: 106582:tmem47
uniprot id: A0A3P9B2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

106582:mtmr10
gene id: 106582:mtmr10
uniprot id: A0A3P9C9Q9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

106582:copg2
gene id: 106582:copg2
uniprot id: A0A3P9BG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

106582:agap3
gene id: 106582:agap3
uniprot id: A0A3P9DGE0
names: Similarity
messages: Belongs to the centaurin gamma-like family.

106582:pc
gene id: 106582:pc
uniprot id: A0A3P9B0W7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

106582:acer2
gene id: 106582:acer2
uniprot id: A0A3P9D7L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:psmd7
gene id: 106582:psmd7
uniprot id: A0A3P9CVA1
names: Similarity
messages: Belongs to the peptidase M67A family.

106582:paip2b
gene id: 106582:paip2b
uniprot id: A0A3P9B5Y4
uniprot id: A0A3P9B604
names: Similarity
messages: Belongs to the PAIP2 family.

106582:LOC101468970
gene id: 106582:LOC101468970
uniprot id: A0A3P9BKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

106582:alg13
gene id: 106582:alg13
uniprot id: A0A3P9BA76
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

106582:LOC101477082
gene id: 106582:LOC101477082
uniprot id: A0A3P9CCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

106582:ahcyl2
gene id: 106582:ahcyl2
uniprot id: A0A3P9C151
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

106582:LOC101487629
gene id: 106582:LOC101487629
uniprot id: A0A3P9C2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

106582:LOC101480675
gene id: 106582:LOC101480675
uniprot id: A0A3P9ARD4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

106582:LOC101476083
gene id: 106582:LOC101476083
uniprot id: A0A3P9CIS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101487119
gene id: 106582:LOC101487119
uniprot id: A0A3P9BMY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

106582:LOC101482875
gene id: 106582:LOC101482875
uniprot id: A0A3P9C9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

106582:cacng5
gene id: 106582:cacng5
uniprot id: A0A3P9AXN0
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

106582:tspan33
gene id: 106582:tspan33
uniprot id: A0A3P9BHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101469529
gene id: 106582:LOC101469529
uniprot id: A0A3P9CKB7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:mtm1
gene id: 106582:mtm1
uniprot id: A0A3P9C482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

106582:LOC101482995
gene id: 106582:LOC101482995
uniprot id: A0A3P9BP16
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:b3galt1
gene id: 106582:b3galt1
uniprot id: A0A3P9BFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:dnm1
gene id: 106582:dnm1
uniprot id: A0A3P9CU22
uniprot id: A0A3P9CV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

106582:rpl35
gene id: 106582:rpl35
uniprot id: A0A3P9CPM9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

106582:sv2c
gene id: 106582:sv2c
uniprot id: A0A3P9CDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

106582:ampd1
gene id: 106582:ampd1
uniprot id: A0A3P9D456
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106582:LOC101470930
gene id: 106582:LOC101470930
uniprot id: A0A3P9BDX3
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101475920
gene id: 106582:LOC101475920
uniprot id: A0A3P9CSV9
names: Subcellular Location Annotation
messages: Nucleus

106582:ctu1
gene id: 106582:ctu1
uniprot id: A0A3P9CT51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

106582:tekt4
gene id: 106582:tekt4
uniprot id: A0A3P9BGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

106582:rps15a
gene id: 106582:rps15a
uniprot id: A0A3P9BSP9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

106582:bet1
gene id: 106582:bet1
uniprot id: A0A3P9BMG9
names: Subcellular Location Annotation
messages: Membrane

106582:sf3b3
gene id: 106582:sf3b3
uniprot id: A0A3P9BWZ9
names: Subcellular Location Annotation
messages: Nucleus

106582:ppil4
gene id: 106582:ppil4
uniprot id: A0A3P9CEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:LOC101466805
gene id: 106582:LOC101466805
uniprot id: A0A3P9B699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

106582:slc7a5
gene id: 106582:slc7a5
uniprot id: A0A3P9BU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

106582:LOC101482074
gene id: 106582:LOC101482074
uniprot id: A0A3P9BN76
uniprot id: A0A3P9BP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

106582:LOC101465314
gene id: 106582:LOC101465314
uniprot id: A0A3P9CHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

106582:tsg101
gene id: 106582:tsg101
uniprot id: A0A3P9CN59
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

106582:LOC101468276
gene id: 106582:LOC101468276
uniprot id: A0A3P9C776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

106582:ap2s1
gene id: 106582:ap2s1
uniprot id: A0A3P9CHR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

106582:ccnc
gene id: 106582:ccnc
uniprot id: A0A3P9CCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

106582:trappc3
gene id: 106582:trappc3
uniprot id: A0A3P9BVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

106582:LOC101486189
gene id: 106582:LOC101486189
uniprot id: A0A3P9D807
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:fkrp
gene id: 106582:fkrp
uniprot id: A0A3P9CHH4
names: Similarity
messages: Belongs to the LicD transferase family.

106582:LOC101481989
gene id: 106582:LOC101481989
uniprot id: A0A3P9AWK4
uniprot id: A0A3P9AWK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

106582:trappc2l
gene id: 106582:trappc2l
uniprot id: A0A3P9AYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

106582:LOC101469335
gene id: 106582:LOC101469335
uniprot id: A0A3P9BQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

106582:dag1
gene id: 106582:dag1
uniprot id: A0A3P9BNF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

106582:cflar
gene id: 106582:cflar
uniprot id: A0A3P9BR91
names: Similarity
messages: Belongs to the peptidase C14A family.

106582:LOC101482742
gene id: 106582:LOC101482742
uniprot id: A0A3P9B0L5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

106582:LOC101482878
gene id: 106582:LOC101482878
uniprot id: A0A3P9DLT6
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

106582:smarcd3
gene id: 106582:smarcd3
uniprot id: A0A3P9CQJ7
uniprot id: A0A3P9CRG6
names: Similarity
messages: Belongs to the SMARCD family.

106582:kcnc4
gene id: 106582:kcnc4
uniprot id: A0A3P9BFP9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC106674830
gene id: 106582:LOC106674830
uniprot id: A0A3P9CZW0
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:tmem14a
gene id: 106582:tmem14a
uniprot id: A0A3P9B7G8
names: Similarity
messages: Belongs to the TMEM14 family.

106582:LOC101469231
gene id: 106582:LOC101469231
uniprot id: A0A3P9B0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101473981
gene id: 106582:LOC101473981
uniprot id: A0A3P9BH40
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

106582:LOC101469033
gene id: 106582:LOC101469033
uniprot id: A0A3P9CEE6
names: Similarity
messages: Belongs to the canopy family.

106582:LOC101471639
gene id: 106582:LOC101471639
uniprot id: A0A3P9DKG1
names: Similarity
messages: Belongs to the synapsin family.

106582:slc7a7
gene id: 106582:slc7a7
uniprot id: A0A3P9D1G9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469758
gene id: 106582:LOC101469758
uniprot id: A0A3P9C960
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:tmem86a
gene id: 106582:tmem86a
uniprot id: A0A3P9CMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

106582:eif5a
gene id: 106582:eif5a
uniprot id: A0A3P9D3J2
uniprot id: A0A3P9D3J9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

106582:LOC101469831
gene id: 106582:LOC101469831
uniprot id: A0A3P9CPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

106582:LOC101468046
gene id: 106582:LOC101468046
uniprot id: A0A3P9CJK7
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

106582:LOC101480678
gene id: 106582:LOC101480678
uniprot id: A0A3P9D295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

106582:lyve1
gene id: 106582:lyve1
uniprot id: A0A3P9CBX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rdh12
gene id: 106582:rdh12
uniprot id: A0A3P9BY28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:s1pr1
gene id: 106582:s1pr1
uniprot id: A0A3P9CQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:gins4
gene id: 106582:gins4
uniprot id: A0A3P9BYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

106582:LOC101475804
gene id: 106582:LOC101475804
uniprot id: A0A3P9CPN7
names: Similarity
messages: Belongs to the peptidase S9A family.

106582:cdk5
gene id: 106582:cdk5
uniprot id: A0A3P9DGI7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:psma5
gene id: 106582:psma5
uniprot id: A0A3P9ARV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:LOC101471174
gene id: 106582:LOC101471174
uniprot id: A0A3P9CGI2
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

106582:LOC101487275
gene id: 106582:LOC101487275
uniprot id: A0A3P9DQJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101464818
gene id: 106582:LOC101464818
uniprot id: A0A3P9CLQ1
names: Similarity
messages: Belongs to the alkaline phosphatase family.

106582:lg12h12orf43
gene id: 106582:lg12h12orf43
uniprot id: A0A3P9ARK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

106582:LOC101487772
gene id: 106582:LOC101487772
uniprot id: A0A3P9BHY6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106582:agk
gene id: 106582:agk
uniprot id: A0A3P9CJ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

106582:slc30a7
gene id: 106582:slc30a7
uniprot id: A0A3P9CPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

106582:ezr
gene id: 106582:ezr
uniprot id: A0A3P9AUR5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:mtmr9
gene id: 106582:mtmr9
uniprot id: A0A3P9CGZ4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

106582:sike1
gene id: 106582:sike1
uniprot id: A0A3P9D3X1
names: Similarity
messages: Belongs to the SIKE family.

106582:ccnb3
gene id: 106582:ccnb3
uniprot id: A0A3P9CYX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:tshz1
gene id: 106582:tshz1
uniprot id: A0A3P9BIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

106582:bmpr1a
gene id: 106582:bmpr1a
uniprot id: A0A3P9B7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:derl2
gene id: 106582:derl2
uniprot id: A0A3P9BRM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:vldlr
gene id: 106582:vldlr
uniprot id: A0A3P9CAU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

106582:yes1
gene id: 106582:yes1
uniprot id: A0A3P9AWJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:gpm6a
gene id: 106582:gpm6a
uniprot id: A0A3P9AVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

106582:ccny
gene id: 106582:ccny
uniprot id: A0A3P9CKN9
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

106582:LOC101465485
gene id: 106582:LOC101465485
uniprot id: A0A3P9DHT0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

106582:LOC101468757
gene id: 106582:LOC101468757
uniprot id: A0A3P9C3D4
uniprot id: A0A3P9C3K2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

106582:phf2
gene id: 106582:phf2
uniprot id: A0A3P9BFQ7
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

106582:twsg1
gene id: 106582:twsg1
uniprot id: A0A3P9DD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

106582:LOC101479331
gene id: 106582:LOC101479331
uniprot id: A0A3P9CPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101469665
gene id: 106582:LOC101469665
uniprot id: A0A3P9C5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

106582:LOC101464251
gene id: 106582:LOC101464251
uniprot id: A0A3P9BWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

106582:ppp4r3b
gene id: 106582:ppp4r3b
uniprot id: A0A3P9DR03
names: Similarity
messages: Belongs to the SMEK family.

106582:LOC101484099
gene id: 106582:LOC101484099
uniprot id: A0A3P9BH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

106582:LOC101467075
gene id: 106582:LOC101467075
uniprot id: A0A3P9C4E7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:agpat5
gene id: 106582:agpat5
uniprot id: A0A3P9B7A3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:LOC101487609
gene id: 106582:LOC101487609
uniprot id: A0A3P9CG89
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

106582:LOC101467832
gene id: 106582:LOC101467832
uniprot id: A0A3P9B1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

106582:nagpa
gene id: 106582:nagpa
uniprot id: A0A3P9BQC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101472907
gene id: 106582:LOC101472907
uniprot id: A0A3P9CM92
names: Similarity
messages: Belongs to the OSBP family.

106582:cdc45
gene id: 106582:cdc45
uniprot id: A0A3P9BSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

106582:dynlrb1
gene id: 106582:dynlrb1
uniprot id: A0A3P9BRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

106582:LOC101475982
gene id: 106582:LOC101475982
uniprot id: A0A3P9CEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

106582:gnpnat1
gene id: 106582:gnpnat1
uniprot id: A0A3P9BRM0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

106582:dpagt1
gene id: 106582:dpagt1
uniprot id: A0A3P9CJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:nr1h3
gene id: 106582:nr1h3
uniprot id: A0A3P9C8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:sf3a1
gene id: 106582:sf3a1
uniprot id: A0A3P9BSB3
names: Subcellular Location Annotation
messages: Nucleus

106582:pbx3
gene id: 106582:pbx3
uniprot id: A0A3P9BQU7
uniprot id: A0A3P9BRQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

106582:vsx2
gene id: 106582:vsx2
uniprot id: A0A3P9BQH1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101486340
gene id: 106582:LOC101486340
uniprot id: A0A3P9DQ18
names: Similarity
messages: Belongs to the NGF-beta family.

106582:LOC101483705
gene id: 106582:LOC101483705
uniprot id: A0A3P9C3W0
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101473111
gene id: 106582:LOC101473111
uniprot id: A0A3P9B1G0
names: Subcellular Location Annotation
messages: Nucleus

106582:cuedc2
gene id: 106582:cuedc2
uniprot id: A0A3P9DS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

106582:tmem165
gene id: 106582:tmem165
uniprot id: A0A3P9CXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

106582:LOC101476645
gene id: 106582:LOC101476645
uniprot id: A0A3P9D9V6
uniprot id: A0A3P9DBJ1
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

106582:LOC101473121
gene id: 106582:LOC101473121
uniprot id: A0A3P9DS51
uniprot id: A0A3P9DSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

106582:hyou1
gene id: 106582:hyou1
uniprot id: A0A3P9DAH1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:ggps1
gene id: 106582:ggps1
uniprot id: A0A3P9BTA4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

106582:LOC101467549
gene id: 106582:LOC101467549
uniprot id: A0A3P9DPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

106582:ogt
gene id: 106582:ogt
uniprot id: A0A3P9BWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

106582:LOC101479232
gene id: 106582:LOC101479232
uniprot id: A0A3P9C1Z4
names: Similarity
messages: Belongs to the arrestin family.

106582:LOC101481208
gene id: 106582:LOC101481208
uniprot id: A0A3P9DI12
uniprot id: A0A3P9DIN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

106582:LOC101483027
gene id: 106582:LOC101483027
uniprot id: A0A3P9AT13
uniprot id: A0A3P9AT25
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101463742
gene id: 106582:LOC101463742
uniprot id: A0A3P9CS26
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

106582:coq4
gene id: 106582:coq4
uniprot id: A0A3P9CTE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

106582:LOC101485159
gene id: 106582:LOC101485159
uniprot id: A0A3P9B192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

106582:LOC101477732
gene id: 106582:LOC101477732
uniprot id: A0A3P9DNB2
uniprot id: A0A3P9DP77
names: Similarity
messages: Belongs to the DNase I family.

106582:rps5
gene id: 106582:rps5
uniprot id: A0A3P9DM42
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

106582:LOC101472305
gene id: 106582:LOC101472305
uniprot id: A0A3P9BAS4
names: Similarity
messages: Belongs to the peptidase S1B family.

106582:LOC101470709
gene id: 106582:LOC101470709
uniprot id: A0A3P9D6D0
names: Subcellular Location Annotation
messages: Membrane

106582:eif4e
gene id: 106582:eif4e
uniprot id: A0A3P9BIF0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

106582:ncstn
gene id: 106582:ncstn
uniprot id: A0A3P9DDI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

106582:LOC101487842
gene id: 106582:LOC101487842
uniprot id: A0A3P9D276
names: Similarity
messages: Belongs to the intermediate filament family.

106582:pmpca
gene id: 106582:pmpca
uniprot id: A0A3P9C8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix
messages: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

106582:lhx5
gene id: 106582:lhx5
uniprot id: A0A3P9BHK8
names: Subcellular Location Annotation
messages: Nucleus

106582:washc1
gene id: 106582:washc1
uniprot id: A0A3P9CY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

106582:LOC101482322
gene id: 106582:LOC101482322
uniprot id: A0A3P9BCP4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469070
gene id: 106582:LOC101469070
uniprot id: A0A3P9AUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101477424
gene id: 106582:LOC101477424
uniprot id: A0A3P9CAN5
names: Similarity
messages: Belongs to the cytochrome b5 family.

106582:LOC101486827
gene id: 106582:LOC101486827
uniprot id: A0A3P9BSX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:uchl5
gene id: 106582:uchl5
uniprot id: A0A3P9CGK5
names: Similarity
messages: Belongs to the peptidase C12 family.

106582:tex261
gene id: 106582:tex261
uniprot id: A0A3P9D160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

106582:gpbp1l1
gene id: 106582:gpbp1l1
uniprot id: A0A3P9BU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

106582:rhbdf1
gene id: 106582:rhbdf1
uniprot id: A0A3P9D4V1
uniprot id: A0A3P9D542
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

106582:nip7
gene id: 106582:nip7
uniprot id: A0A3P9BSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

106582:sdhaf4
gene id: 106582:sdhaf4
uniprot id: A0A3P9CQH9
names: Similarity
messages: Belongs to the SDHAF4 family.

106582:LOC101465725
gene id: 106582:LOC101465725
uniprot id: A0A3P9D297
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

106582:hsdl2
gene id: 106582:hsdl2
uniprot id: A0A3P9DAD6
names: Subcellular Location Annotation
messages: Peroxisome

106582:LOC101479377
gene id: 106582:LOC101479377
uniprot id: A0A3P9CEN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:il6st
gene id: 106582:il6st
uniprot id: A0A3P9BQ10
uniprot id: A0A3P9BQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

106582:LOC101478036
gene id: 106582:LOC101478036
uniprot id: A0A3P9D3L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

106582:ccdc85b
gene id: 106582:ccdc85b
uniprot id: A0A3P9BAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

106582:LOC101475800
gene id: 106582:LOC101475800
uniprot id: A0A3P9BGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

106582:pcmtd1
gene id: 106582:pcmtd1
uniprot id: A0A3P9DFR5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106582:pxdn
gene id: 106582:pxdn
uniprot id: A0A3P9B625
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101471959
gene id: 106582:LOC101471959
uniprot id: A0A3P9DEH1
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101466041
gene id: 106582:LOC101466041
uniprot id: A0A3P9DQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:hdac8
gene id: 106582:hdac8
uniprot id: A0A3P9CXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

106582:LOC101480714
gene id: 106582:LOC101480714
uniprot id: A0A3P9CI17
uniprot id: A0A3P9CI29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101472374
gene id: 106582:LOC101472374
uniprot id: A0A3P9B9C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:mcm2
gene id: 106582:mcm2
uniprot id: A0A3P9CJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

106582:mapkap1
gene id: 106582:mapkap1
uniprot id: A0A3P9BZJ7
names: Similarity
messages: Belongs to the SIN1 family.

106582:arl6ip5
gene id: 106582:arl6ip5
uniprot id: A0A3P9DLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

106582:chga
gene id: 106582:chga
uniprot id: A0A3P9C578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

106582:tfap2a
gene id: 106582:tfap2a
uniprot id: A0A3P9CLE4
uniprot id: A0A3P9CM87
uniprot id: A0A3P9CMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

106582:med8
gene id: 106582:med8
uniprot id: A0A3P9BVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

106582:pdhb
gene id: 106582:pdhb
uniprot id: A0A3P9CLC4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

106582:LOC101468024
gene id: 106582:LOC101468024
uniprot id: A0A3P9CA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

106582:LOC101470625
gene id: 106582:LOC101470625
uniprot id: A0A3P9CVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

106582:LOC101484325
gene id: 106582:LOC101484325
uniprot id: A0A3P9B2A0
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

106582:LOC101475321
gene id: 106582:LOC101475321
uniprot id: A0A3P9CPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101471322
gene id: 106582:LOC101471322
uniprot id: A0A3P9BRT5
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:kcng1
gene id: 106582:kcng1
uniprot id: A0A3P9DA53
names: Subcellular Location Annotation
messages: Membrane

106582:atg5
gene id: 106582:atg5
uniprot id: A0A3P9BT81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

106582:lipc
gene id: 106582:lipc
uniprot id: A0A3P9C8I2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Secreted

106582:LOC101480309
gene id: 106582:LOC101480309
uniprot id: A0A3P9DDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101478071
gene id: 106582:LOC101478071
uniprot id: A0A3P9BNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

106582:riox1
gene id: 106582:riox1
uniprot id: A0A3P9AX70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

106582:LOC101470312
gene id: 106582:LOC101470312
uniprot id: A0A3P9CW23
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

106582:LOC101477846
gene id: 106582:LOC101477846
uniprot id: A0A3P9D7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

106582:nr2f1
gene id: 106582:nr2f1
uniprot id: A0A3P9C8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:cldn19
gene id: 106582:cldn19
uniprot id: A0A3P9BIQ6
uniprot id: A0A3P9BIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101467519
gene id: 106582:LOC101467519
uniprot id: A0A3P9CLS1
uniprot id: A0A3P9CNB2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

106582:mmp15
gene id: 106582:mmp15
uniprot id: A0A3P9AR22
names: Similarity
messages: Belongs to the peptidase M10A family.

106582:med6
gene id: 106582:med6
uniprot id: A0A3P9BXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:mapk8
gene id: 106582:mapk8
uniprot id: A0A3P9BGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

106582:ndufv2
gene id: 106582:ndufv2
uniprot id: A0A3P9DDR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

106582:LOC101483538
gene id: 106582:LOC101483538
uniprot id: A0A3P9C7U7
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

106582:LOC101466613
gene id: 106582:LOC101466613
uniprot id: A0A3P9CUN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101480662
gene id: 106582:LOC101480662
uniprot id: A0A3P9B3M7
uniprot id: A0A3P9B3M9
uniprot id: A0A3P9B3N9
uniprot id: A0A3P9B402
names: Similarity
messages: Belongs to the dysbindin family.

106582:LOC101469202
gene id: 106582:LOC101469202
uniprot id: A0A3P9ASD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:med21
gene id: 106582:med21
uniprot id: A0A3P9CDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:nox5
gene id: 106582:nox5
uniprot id: A0A3P9B0W3
names: Subcellular Location Annotation
messages: Membrane

106582:ogn
gene id: 106582:ogn
uniprot id: A0A3P9CKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

106582:LOC101471595
gene id: 106582:LOC101471595
uniprot id: A0A3P9DA17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

106582:LOC101465806
gene id: 106582:LOC101465806
uniprot id: A0A3P9BLW5
names: Subcellular Location Annotation
messages: Nucleus

106582:tfcp2
gene id: 106582:tfcp2
uniprot id: A0A3P9DL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

106582:sqle
gene id: 106582:sqle
uniprot id: A0A3P9C2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

106582:LOC101470254
gene id: 106582:LOC101470254
uniprot id: A0A3P9BIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

106582:LOC101480089
gene id: 106582:LOC101480089
uniprot id: A0A3P9CYK7
names: Similarity
messages: Belongs to the TGF-beta family.

106582:kcnv1
gene id: 106582:kcnv1
uniprot id: A0A3P9CKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

106582:LOC101475422
gene id: 106582:LOC101475422
uniprot id: A0A3P9C2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

106582:LOC101469582
gene id: 106582:LOC101469582
uniprot id: A0A3P9DNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

106582:LOC101471767
gene id: 106582:LOC101471767
uniprot id: A0A3P9CJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

106582:LOC101479383
gene id: 106582:LOC101479383
uniprot id: A0A3P9DGL3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101467603
gene id: 106582:LOC101467603
uniprot id: A0A3P9D8Y0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101484228
gene id: 106582:LOC101484228
uniprot id: A0A3P9BWF6
uniprot id: A0A3P9BWG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101486288
gene id: 106582:LOC101486288
uniprot id: A0A3P9BCH6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101471460
gene id: 106582:LOC101471460
uniprot id: A0A3P9CFL6
names: Similarity
messages: Belongs to the RBR family.

106582:LOC101486037
gene id: 106582:LOC101486037
uniprot id: A0A3P9D8I1
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

106582:LOC101476800
gene id: 106582:LOC101476800
uniprot id: A0A3P9AX73
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

106582:LOC101485403
gene id: 106582:LOC101485403
uniprot id: A0A3P9C8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:bcap31
gene id: 106582:bcap31
uniprot id: A0A3P9DNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

106582:LOC101481771
gene id: 106582:LOC101481771
uniprot id: A0A3P9B1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101468561
gene id: 106582:LOC101468561
uniprot id: A0A3P9BX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

106582:polr3k
gene id: 106582:polr3k
uniprot id: A0A3P9D7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

106582:gphn
gene id: 106582:gphn
uniprot id: A0A3P9AWR4
uniprot id: A0A3P9AXF2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

106582:phlda2
gene id: 106582:phlda2
uniprot id: A0A3P9CMG9
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101477768
gene id: 106582:LOC101477768
uniprot id: A0A3P9DIR8
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

106582:LOC101487010
gene id: 106582:LOC101487010
uniprot id: A0A3P9BXZ7
names: Similarity
messages: Belongs to the beta-catenin family.

106582:LOC101475434
gene id: 106582:LOC101475434
uniprot id: A0A3P9CYD8
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:ctgf
gene id: 106582:ctgf
uniprot id: A0A3P9C583
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:nol11
gene id: 106582:nol11
uniprot id: A0A3P9AXX0
names: Subcellular Location Annotation
messages: nucleolus

106582:LOC101483744
gene id: 106582:LOC101483744
uniprot id: A0A3P9CMT2
names: Subcellular Location Annotation
messages: perinuclear region

106582:pde10a
gene id: 106582:pde10a
uniprot id: A0A3P9BMQ7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:LOC101486261
gene id: 106582:LOC101486261
uniprot id: A0A3P9AR03
names: Similarity
messages: Belongs to the SEC6 family.

106582:sh3pxd2b
gene id: 106582:sh3pxd2b
uniprot id: A0A3P9BMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

106582:pax6
gene id: 106582:pax6
uniprot id: A0A3P9C0Y4
uniprot id: A0A3P9C1X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:immp1l
gene id: 106582:immp1l
uniprot id: A0A3P9C1P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

106582:LOC101483887
gene id: 106582:LOC101483887
uniprot id: A0A3P9BLP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:prrx1
gene id: 106582:prrx1
uniprot id: A0A3P9CP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

106582:rnps1
gene id: 106582:rnps1
uniprot id: A0A3P9C4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

106582:aph1a
gene id: 106582:aph1a
uniprot id: A0A3P9CDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

106582:usp15
gene id: 106582:usp15
uniprot id: A0A3P9CEK4
uniprot id: A0A3P9CF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101475176
gene id: 106582:LOC101475176
uniprot id: A0A3P9CRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

106582:LOC101484027
gene id: 106582:LOC101484027
uniprot id: A0A3P9AT82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

106582:LOC105941456
gene id: 106582:LOC105941456
uniprot id: A0A3P9CV42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:lonp1
gene id: 106582:lonp1
uniprot id: A0A3P9CNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

106582:LOC101482208
gene id: 106582:LOC101482208
uniprot id: A0A3P9CP92
uniprot id: A0A3P9CP99
names: Subcellular Location Annotation
messages: Membrane

106582:acadm
gene id: 106582:acadm
uniprot id: A0A3P9DDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

106582:LOC101467414
gene id: 106582:LOC101467414
uniprot id: A0A3P9B958
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

106582:gdf15
gene id: 106582:gdf15
uniprot id: A0A3P9B574
names: Similarity
messages: Belongs to the TGF-beta family.

106582:top3b
gene id: 106582:top3b
uniprot id: A0A3P9B6V4
uniprot id: A0A3P9B6V9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

106582:dnajb14
gene id: 106582:dnajb14
uniprot id: A0A3P9CWM7
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476421
gene id: 106582:LOC101476421
uniprot id: A0A3P9DNC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

106582:pomt2
gene id: 106582:pomt2
uniprot id: A0A3P9BQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

106582:sardh
gene id: 106582:sardh
uniprot id: A0A3P9CKY8
names: Similarity
messages: Belongs to the GcvT family.

106582:LOC101469034
gene id: 106582:LOC101469034
uniprot id: A0A3P9C0E6
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

106582:LOC101480153
gene id: 106582:LOC101480153
uniprot id: A0A3P9BN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:prkaa1
gene id: 106582:prkaa1
uniprot id: A0A3P9B4M7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

106582:mrps24
gene id: 106582:mrps24
uniprot id: A0A3P9C2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

106582:APK84 gp10
gene id: 106582:APK84_gp10
uniprot id: A0A0K2CIR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

106582:emp2
gene id: 106582:emp2
uniprot id: A0A3P9BL22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

106582:metap1
gene id: 106582:metap1
uniprot id: A0A3P9BI88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

106582:LOC101465777
gene id: 106582:LOC101465777
uniprot id: A0A3P9DHC7
uniprot id: A0A3P9DI28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

106582:ddx3x
gene id: 106582:ddx3x
uniprot id: A0A3P9D0R3
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:LOC101481864
gene id: 106582:LOC101481864
uniprot id: A0A3P9D847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101472064
gene id: 106582:LOC101472064
uniprot id: A0A3P9ASF9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:LOC101476878
gene id: 106582:LOC101476878
uniprot id: A0A3P9CLD3
names: Similarity
messages: Belongs to the perilipin family.

106582:LOC101482464
gene id: 106582:LOC101482464
uniprot id: A0A3P9CMJ3
uniprot id: A0A3P9CN90
uniprot id: A0A3P9CP32
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

106582:kiaa0391
gene id: 106582:kiaa0391
uniprot id: A0A3P9BLQ2
names: Similarity
messages: Belongs to the PPR family. P subfamily.

106582:LOC101466351
gene id: 106582:LOC101466351
uniprot id: A0A3P9DR45
names: Subcellular Location Annotation
messages: Nucleus

106582:ints13
gene id: 106582:ints13
uniprot id: A0A3P9BNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

106582:znf592
gene id: 106582:znf592
uniprot id: A0A3P9D5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

106582:sept3
gene id: 106582:sept3
uniprot id: A0A3P9DCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

106582:asah1
gene id: 106582:asah1
uniprot id: A0A3P9BJD2
names: Similarity
messages: Belongs to the acid ceramidase family.

106582:slc16a9
gene id: 106582:slc16a9
uniprot id: A0A3P9DPX2
names: Subcellular Location Annotation
messages: Membrane

106582:eme1
gene id: 106582:eme1
uniprot id: A0A3P9B388
names: Similarity
messages: Belongs to the EME1/MMS4 family.

106582:LOC101469516
gene id: 106582:LOC101469516
uniprot id: A0A3P9C1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101471485
gene id: 106582:LOC101471485
uniprot id: A0A3P9BIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

106582:scrn2
gene id: 106582:scrn2
uniprot id: A0A3P9C333
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

106582:kcns2
gene id: 106582:kcns2
uniprot id: A0A3P9DHZ5
names: Subcellular Location Annotation
messages: Membrane

106582:dctpp1
gene id: 106582:dctpp1
uniprot id: A0A3P9BMX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

106582:max
gene id: 106582:max
uniprot id: A0A3P9B2I4
names: Similarity
messages: Belongs to the MAX family.

106582:panx1
gene id: 106582:panx1
uniprot id: A0A3P9BTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

106582:LOC105941361
gene id: 106582:LOC105941361
uniprot id: A0A3P9C626
names: Similarity
messages: Belongs to the FXYD family.

106582:stoml2
gene id: 106582:stoml2
uniprot id: A0A3P9CH76
names: Similarity
messages: Belongs to the band 7/mec-2 family.

106582:lclat1
gene id: 106582:lclat1
uniprot id: A0A3P9AY69
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:slc6a11
gene id: 106582:slc6a11
uniprot id: A0A3P9C7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:psmb1
gene id: 106582:psmb1
uniprot id: A0A3P9BY57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

106582:pck1
gene id: 106582:pck1
uniprot id: A0A3P9CJE9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

106582:nr3c2
gene id: 106582:nr3c2
uniprot id: A0A3P9BPZ2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101483856
gene id: 106582:LOC101483856
uniprot id: A0A3P9B0H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

106582:LOC101473974
gene id: 106582:LOC101473974
uniprot id: A0A3P9DJ23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC101481337
gene id: 106582:LOC101481337
uniprot id: A0A3P9D050
names: Similarity
messages: Belongs to the actin family.

106582:dhrs3
gene id: 106582:dhrs3
uniprot id: A0A3P9AUG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:wisp3
gene id: 106582:wisp3
uniprot id: A0A3P9CFR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101480716
gene id: 106582:LOC101480716
uniprot id: A0A3P9BY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:s1pr2
gene id: 106582:s1pr2
uniprot id: A0A3P9CTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:snrpc
gene id: 106582:snrpc
uniprot id: A0A3P9AYN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

106582:snx17
gene id: 106582:snx17
uniprot id: A0A3P9CGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

106582:LOC101467346
gene id: 106582:LOC101467346
uniprot id: A0A3P9BRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

106582:LOC101465674
gene id: 106582:LOC101465674
uniprot id: A0A3P9BRK8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:lctl
gene id: 106582:lctl
uniprot id: A0A3P9D777
uniprot id: A0A3P9D781
uniprot id: A0A3P9D7U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

106582:tctex1d2
gene id: 106582:tctex1d2
uniprot id: A0A3P9CM79
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

106582:LOC101476824
gene id: 106582:LOC101476824
uniprot id: A0A3P9AXR0
names: Similarity
messages: Belongs to the SUI1 family.

106582:LOC101475234
gene id: 106582:LOC101475234
uniprot id: A0A3P9BAN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101475199
gene id: 106582:LOC101475199
uniprot id: A0A3P9CI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:actb
gene id: 106582:actb
uniprot id: A0A3P9BIS7
names: Similarity
messages: Belongs to the actin family.

106582:prkcd
gene id: 106582:prkcd
uniprot id: A0A3P9BR25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

106582:rtraf
gene id: 106582:rtraf
uniprot id: A0A3P9AWP3
names: Similarity
messages: Belongs to the RTRAF family.

106582:LOC101464108
gene id: 106582:LOC101464108
uniprot id: A0A3P9D0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:sdha
gene id: 106582:sdha
uniprot id: A0A3P9BGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

106582:LOC101487540
gene id: 106582:LOC101487540
uniprot id: A0A3P9D6X4
names: Subcellular Location Annotation
messages: Secreted

106582:LOC101469313
gene id: 106582:LOC101469313
uniprot id: A0A3P9DHE8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

106582:plxna3
gene id: 106582:plxna3
uniprot id: A0A3P9DNL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101469023
gene id: 106582:LOC101469023
uniprot id: A0A3P9AQU1
names: Subcellular Location Annotation
messages: Secreted

106582:neurod2
gene id: 106582:neurod2
uniprot id: A0A3P9D7H3
names: Subcellular Location Annotation
messages: Nucleus

106582:rptor
gene id: 106582:rptor
uniprot id: A0A3P9C1I1
uniprot id: A0A3P9C276
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

106582:prpf31
gene id: 106582:prpf31
uniprot id: A0A3P9CIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

106582:LOC101478854
gene id: 106582:LOC101478854
uniprot id: A0A3P9DFP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

106582:LOC101487832
gene id: 106582:LOC101487832
uniprot id: A0A3P9BDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101484212
gene id: 106582:LOC101484212
uniprot id: A0A3P9BE90
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

106582:LOC101478210
gene id: 106582:LOC101478210
uniprot id: A0A3P9AXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

106582:pla2g12a
gene id: 106582:pla2g12a
uniprot id: A0A3P9CV49
names: Subcellular Location Annotation
messages: Secreted

106582:LOC101482753
gene id: 106582:LOC101482753
uniprot id: A0A3P9BIV1
names: Similarity
messages: Belongs to the peptidase S1C family.

106582:LOC101469518
gene id: 106582:LOC101469518
uniprot id: A0A3P9CEW8
names: Similarity
messages: Belongs to the SEC6 family.

106582:LOC101471309
gene id: 106582:LOC101471309
uniprot id: A0A3P9BI07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

106582:mccc2
gene id: 106582:mccc2
uniprot id: A0A3P9C4K8
names: Similarity
messages: Belongs to the AccD/PCCB family.

106582:LOC101472083
gene id: 106582:LOC101472083
uniprot id: A0A3P9BSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

106582:LOC101481544
gene id: 106582:LOC101481544
uniprot id: A0A3P9BKT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

106582:LOC101477034
gene id: 106582:LOC101477034
uniprot id: A0A3P9BUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

106582:LOC101469368
gene id: 106582:LOC101469368
uniprot id: A0A3P9CLQ2
names: Subcellular Location Annotation
messages: Nucleus
messages: extracellular exosome

106582:selp
gene id: 106582:selp
uniprot id: A0A3P9BJB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:fgb
gene id: 106582:fgb
uniprot id: A0A3P9DSU1
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

106582:sh3rf3
gene id: 106582:sh3rf3
uniprot id: A0A3P9BVH9
names: Similarity
messages: Belongs to the SH3RF family.

106582:LOC101483987
gene id: 106582:LOC101483987
uniprot id: A0A3P9C8Y4
uniprot id: A0A3P9C9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

106582:kdelc1
gene id: 106582:kdelc1
uniprot id: A0A3P9B004
names: Similarity
messages: Belongs to the KDELC family.

106582:klc2
gene id: 106582:klc2
uniprot id: A0A3P9CZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

106582:pnkd
gene id: 106582:pnkd
uniprot id: A0A3P9C437
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

106582:atg4d
gene id: 106582:atg4d
uniprot id: A0A3P9DCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

106582:LOC101475077
gene id: 106582:LOC101475077
uniprot id: A0A3P9AQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

106582:igfbp2
gene id: 106582:igfbp2
uniprot id: A0A3P9CBC3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:ddit3
gene id: 106582:ddit3
uniprot id: A0A3P9BHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

106582:LOC101487023
gene id: 106582:LOC101487023
uniprot id: A0A3P9C0E1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

106582:nuf2
gene id: 106582:nuf2
uniprot id: A0A3P9BIH0
names: Similarity
messages: Belongs to the NUF2 family.

106582:LOC101475856
gene id: 106582:LOC101475856
uniprot id: A0A3P9CUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

106582:LOC101473766
gene id: 106582:LOC101473766
uniprot id: A0A3P9CTE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

106582:ddx41
gene id: 106582:ddx41
uniprot id: A0A3P9BUH8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

106582:dusp1
gene id: 106582:dusp1
uniprot id: A0A3P9BU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

106582:LOC101486310
gene id: 106582:LOC101486310
uniprot id: A0A3P9BZF9
uniprot id: A0A3P9BZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

106582:LOC101476035
gene id: 106582:LOC101476035
uniprot id: A0A3P9D577
names: Similarity
messages: Belongs to the globin family.

106582:rnf8
gene id: 106582:rnf8
uniprot id: A0A3P9AVA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

106582:proc
gene id: 106582:proc
uniprot id: A0A3P9CYS0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:LOC101480515
gene id: 106582:LOC101480515
uniprot id: A0A3P9CFX6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

106582:cxxc4
gene id: 106582:cxxc4
uniprot id: A0A3P9CWV6
names: Subcellular Location Annotation
messages: Cytoplasm

106582:miox
gene id: 106582:miox
uniprot id: A0A3P9CYG5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

106582:LOC101465658
gene id: 106582:LOC101465658
uniprot id: A0A3P9CLN7
uniprot id: A0A3P9CMK4
names: Subcellular Location Annotation
messages: lamellipodium

106582:LOC101484981
gene id: 106582:LOC101484981
uniprot id: A0A3P9DQQ1
names: Similarity
messages: Belongs to the peptidase S1C family.

106582:gpr6
gene id: 106582:gpr6
uniprot id: A0A3P9CLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101479420
gene id: 106582:LOC101479420
uniprot id: A0A3P9AYC6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:bcam
gene id: 106582:bcam
uniprot id: A0A3P9B4P6
uniprot id: A0A3P9B4P8
uniprot id: A0A3P9B4Q4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101473814
gene id: 106582:LOC101473814
uniprot id: A0A3P9DSJ2
names: Subcellular Location Annotation
messages: Secreted

106582:fam219b
gene id: 106582:fam219b
uniprot id: A0A3P9BBG7
names: Similarity
messages: Belongs to the FAM219 family.

106582:engase
gene id: 106582:engase
uniprot id: A0A3P9DA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

106582:LOC101488084
gene id: 106582:LOC101488084
uniprot id: A0A3P9B277
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

106582:rab32
gene id: 106582:rab32
uniprot id: A0A3P9CMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

106582:LOC101471941
gene id: 106582:LOC101471941
uniprot id: A0A3P9BCQ8
names: Subcellular Location Annotation
messages: Membrane

106582:atp5pf
gene id: 106582:atp5pf
uniprot id: A0A3P9BBS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion inner membrane

106582:etfb
gene id: 106582:etfb
uniprot id: A0A3P9BKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

106582:LOC101474847
gene id: 106582:LOC101474847
uniprot id: A0A3P9CUD8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

106582:vopp1
gene id: 106582:vopp1
uniprot id: A0A3P9CF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

106582:foxf1
gene id: 106582:foxf1
uniprot id: A0A3P9C2Y6
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101476785
gene id: 106582:LOC101476785
uniprot id: A0A3P9AZH3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:prkaa2
gene id: 106582:prkaa2
uniprot id: A0A3P9CWR9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

106582:sap18
gene id: 106582:sap18
uniprot id: A0A3P9AX66
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

106582:LOC101485414
gene id: 106582:LOC101485414
uniprot id: A0A3P9BDU2
names: Subcellular Location Annotation
messages: Nucleus

106582:tmc6
gene id: 106582:tmc6
uniprot id: A0A3P9BL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

106582:ncln
gene id: 106582:ncln
uniprot id: A0A3P9B332
names: Similarity
messages: Belongs to the nicastrin family.

106582:LOC101476895
gene id: 106582:LOC101476895
uniprot id: A0A3P9D4K3
names: Similarity
messages: Belongs to the globin family.

106582:cnfn
gene id: 106582:cnfn
uniprot id: A0A3P9B0H5
names: Similarity
messages: Belongs to the cornifelin family.

106582:LOC101477972
gene id: 106582:LOC101477972
uniprot id: A0A3P9CGA4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101469369
gene id: 106582:LOC101469369
uniprot id: A0A3P9AUM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rrp15
gene id: 106582:rrp15
uniprot id: A0A3P9DG49
names: Similarity
messages: Belongs to the RRP15 family.

106582:unc50
gene id: 106582:unc50
uniprot id: A0A3P9CN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

106582:LOC101480137
gene id: 106582:LOC101480137
uniprot id: A0A3P9CG63
names: Similarity
messages: Belongs to the BZW family.

106582:LOC101472812
gene id: 106582:LOC101472812
uniprot id: A0A3P9CEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

106582:LOC101474641
gene id: 106582:LOC101474641
uniprot id: A0A3P9AVY4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106582:pelo
gene id: 106582:pelo
uniprot id: A0A3P9C9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

106582:LOC101482207
gene id: 106582:LOC101482207
uniprot id: A0A3P9CNE6
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

106582:LOC101483618
gene id: 106582:LOC101483618
uniprot id: A0A3P9CQE5
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

106582:hs6st3
gene id: 106582:hs6st3
uniprot id: A0A3P9B3J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

106582:LOC101474456
gene id: 106582:LOC101474456
uniprot id: A0A3P9BX28
uniprot id: A0A3P9BXR5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101468004
gene id: 106582:LOC101468004
uniprot id: A0A3P9CUN5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC106676640
gene id: 106582:LOC106676640
uniprot id: A0A3P9DFM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:fam126a
gene id: 106582:fam126a
uniprot id: A0A3P9BGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

106582:LOC101469646
gene id: 106582:LOC101469646
uniprot id: A0A3P9ARY0
names: Subcellular Location Annotation
messages: Nucleus

106582:mlf1
gene id: 106582:mlf1
uniprot id: A0A3P9CGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

106582:LOC101464840
gene id: 106582:LOC101464840
uniprot id: A0A3P9DD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:LOC101464997
gene id: 106582:LOC101464997
uniprot id: A0A3P9B6L5
uniprot id: A0A3P9B6X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

106582:mfsd11
gene id: 106582:mfsd11
uniprot id: A0A3P9AWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

106582:LOC101467750
gene id: 106582:LOC101467750
uniprot id: A0A3P9C2U0
names: Similarity
messages: Belongs to the TAPR1 family.

106582:tbx2
gene id: 106582:tbx2
uniprot id: A0A3P9AWG3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC101475594
gene id: 106582:LOC101475594
uniprot id: A0A3P9B020
uniprot id: A0A3P9B044
uniprot id: A0A3P9B091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

106582:dlx6
gene id: 106582:dlx6
uniprot id: A0A3P9BPV6
names: Subcellular Location Annotation
messages: Nucleus

106582:idnk
gene id: 106582:idnk
uniprot id: A0A3P9B842
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

106582:creg1
gene id: 106582:creg1
uniprot id: A0A3P9C1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

106582:tnfsf11
gene id: 106582:tnfsf11
uniprot id: A0A3P9D1N1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:LOC101478399
gene id: 106582:LOC101478399
uniprot id: A0A3P9D832
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:fbxo46
gene id: 106582:fbxo46
uniprot id: A0A3P9BAK4
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

106582:LOC101471942
gene id: 106582:LOC101471942
uniprot id: A0A3P9B437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

106582:cav1
gene id: 106582:cav1
uniprot id: A0A3P9C6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

106582:LOC101479924
gene id: 106582:LOC101479924
uniprot id: A0A3P9DB09
names: Similarity
messages: Belongs to the DNase II family.

106582:LOC101486104
gene id: 106582:LOC101486104
uniprot id: A0A3P9ATA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

106582:wnt9a
gene id: 106582:wnt9a
uniprot id: A0A3P9DH29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC106676067
gene id: 106582:LOC106676067
uniprot id: A0A3P9BJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101468590
gene id: 106582:LOC101468590
uniprot id: A0A3P9B1W6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

106582:LOC101478708
gene id: 106582:LOC101478708
uniprot id: A0A3P9D8X8
names: Similarity
messages: Belongs to the angiomotin family.

106582:foxa2
gene id: 106582:foxa2
uniprot id: A0A3P9BCL9
names: Subcellular Location Annotation
messages: Nucleus

106582:cpped1
gene id: 106582:cpped1
uniprot id: A0A3P9BI39
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

106582:taf7l
gene id: 106582:taf7l
uniprot id: A0A3P9BGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

106582:LOC101466725
gene id: 106582:LOC101466725
uniprot id: A0A3P9CM02
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

106582:adamts15
gene id: 106582:adamts15
uniprot id: A0A3P9CVH6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:LOC101479726
gene id: 106582:LOC101479726
uniprot id: A0A3P9D620
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101476977
gene id: 106582:LOC101476977
uniprot id: A0A3P9ATB3
uniprot id: A0A3P9ATD6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

106582:LOC101471836
gene id: 106582:LOC101471836
uniprot id: A0A3P9BDZ3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

106582:LOC101480548
gene id: 106582:LOC101480548
uniprot id: A0A3P9BMW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

106582:LOC101476106
gene id: 106582:LOC101476106
uniprot id: A0A3P9D2R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

106582:LOC101469301
gene id: 106582:LOC101469301
uniprot id: A0A3P9CYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

106582:LOC101471392
gene id: 106582:LOC101471392
uniprot id: A0A3P9DFG7
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

106582:ccnt2
gene id: 106582:ccnt2
uniprot id: A0A3P9AVR5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

106582:LOC101471047
gene id: 106582:LOC101471047
uniprot id: A0A3P9D455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

106582:tet2
gene id: 106582:tet2
uniprot id: A0A3P9CVQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

106582:LOC101478427
gene id: 106582:LOC101478427
uniprot id: A0A3P9BMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome

106582:hprt1
gene id: 106582:hprt1
uniprot id: A0A3P9BE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

106582:eif4a2
gene id: 106582:eif4a2
uniprot id: A0A3P9BGT8
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

106582:LOC101470177
gene id: 106582:LOC101470177
uniprot id: A0A3P9CGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

106582:palld
gene id: 106582:palld
uniprot id: A0A3P9CZX0
names: Subcellular Location Annotation
messages: Membrane

106582:lrp12
gene id: 106582:lrp12
uniprot id: A0A3P9C234
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101468068
gene id: 106582:LOC101468068
uniprot id: A0A3P9BUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:arl2bp
gene id: 106582:arl2bp
uniprot id: A0A3P9DJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

106582:LOC101481975
gene id: 106582:LOC101481975
uniprot id: A0A3P9CHT2
names: Subcellular Location Annotation
messages: Membrane

106582:acmsd
gene id: 106582:acmsd
uniprot id: A0A3P9AVT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

106582:LOC101485664
gene id: 106582:LOC101485664
uniprot id: A0A3P9BL00
names: Subcellular Location Annotation
messages: Membrane

106582:cfap299
gene id: 106582:cfap299
uniprot id: A0A3P9CY47
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

106582:LOC101483716
gene id: 106582:LOC101483716
uniprot id: A0A3P9BYM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101486797
gene id: 106582:LOC101486797
uniprot id: A0A3P9CTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

106582:rps28
gene id: 106582:rps28
uniprot id: A0A3P9B5H5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

106582:b4gat1
gene id: 106582:b4gat1
uniprot id: A0A3P9D015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:slc35f6
gene id: 106582:slc35f6
uniprot id: A0A3P9AUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

106582:LOC101488045
gene id: 106582:LOC101488045
uniprot id: A0A3P9DLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

106582:nr2f6
gene id: 106582:nr2f6
uniprot id: A0A3P9CT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:LOC101469208
gene id: 106582:LOC101469208
uniprot id: A0A3P9CAN0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

106582:LOC101471312
gene id: 106582:LOC101471312
uniprot id: A0A3P9BV82
names: Similarity
messages: Belongs to the DeSI family.

106582:maf1
gene id: 106582:maf1
uniprot id: A0A3P9AUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

106582:LOC101465425
gene id: 106582:LOC101465425
uniprot id: A0A3P9BU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

106582:vps33b
gene id: 106582:vps33b
uniprot id: A0A3P9CG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

106582:LOC101474571
gene id: 106582:LOC101474571
uniprot id: A0A3P9C1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

106582:vti1a
gene id: 106582:vti1a
uniprot id: A0A3P9CGC8
uniprot id: A0A3P9CGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

106582:LOC101476832
gene id: 106582:LOC101476832
uniprot id: A0A3P9C913
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101478147
gene id: 106582:LOC101478147
uniprot id: A0A3P9BUB5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:comp
gene id: 106582:comp
uniprot id: A0A3P9CKS0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101472780
gene id: 106582:LOC101472780
uniprot id: A0A3P9CUY5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

106582:LOC101476378
gene id: 106582:LOC101476378
uniprot id: A0A3P9B087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:exoc3
gene id: 106582:exoc3
uniprot id: A0A3P9CFV3
names: Similarity
messages: Belongs to the SEC6 family.

106582:ap1s1
gene id: 106582:ap1s1
uniprot id: A0A3P9BRW3
uniprot id: A0A3P9BRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

106582:smoc2
gene id: 106582:smoc2
uniprot id: A0A3P9BX27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101476568
gene id: 106582:LOC101476568
uniprot id: A0A3P9D036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:tmem167a
gene id: 106582:tmem167a
uniprot id: A0A3P9CC79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

106582:LOC101482614
gene id: 106582:LOC101482614
uniprot id: A0A3P9CPL9
names: Similarity
messages: Belongs to the intermediate filament family.

106582:LOC101480916
gene id: 106582:LOC101480916
uniprot id: A0A3P9AYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

106582:rtf2
gene id: 106582:rtf2
uniprot id: A0A3P9B9L0
names: Similarity
messages: Belongs to the rtf2 family.

106582:egr3
gene id: 106582:egr3
uniprot id: A0A3P9C3R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

106582:LOC101483484
gene id: 106582:LOC101483484
uniprot id: A0A3P9AQW6
names: Subcellular Location Annotation
messages: Nucleus

106582:dpy19l4
gene id: 106582:dpy19l4
uniprot id: A0A3P9DL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

106582:LOC101473794
gene id: 106582:LOC101473794
uniprot id: A0A3P9BGY1
names: Similarity
messages: Belongs to the asteroid family.

106582:LOC101465952
gene id: 106582:LOC101465952
uniprot id: A0A3P9CJJ4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:LOC101481777
gene id: 106582:LOC101481777
uniprot id: A0A3P9BTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

106582:plppr3
gene id: 106582:plppr3
uniprot id: A0A3P9D115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:LOC101467557
gene id: 106582:LOC101467557
uniprot id: A0A3P9CLT8
names: Similarity
messages: Belongs to the mTERF family.

106582:LOC101476107
gene id: 106582:LOC101476107
uniprot id: A0A3P9DKM6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101472782
gene id: 106582:LOC101472782
uniprot id: A0A3P9BT97
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480520
gene id: 106582:LOC101480520
uniprot id: A0A3P9ARI0
names: Similarity
messages: Belongs to the UPF0687 family.

106582:gpd2
gene id: 106582:gpd2
uniprot id: A0A3P9CEV4
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

106582:LOC101474042
gene id: 106582:LOC101474042
uniprot id: A0A3P9AVA3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106582:vti1b
gene id: 106582:vti1b
uniprot id: A0A3P9BXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

106582:LOC101469849
gene id: 106582:LOC101469849
uniprot id: A0A3P9ASU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

106582:LOC101467847
gene id: 106582:LOC101467847
uniprot id: A0A3P9C9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

106582:elac2
gene id: 106582:elac2
uniprot id: A0A3P9ASG3
names: Similarity
messages: Belongs to the RNase Z family.

106582:LOC101474512
gene id: 106582:LOC101474512
uniprot id: A0A3P9CW73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

106582:LOC101479635
gene id: 106582:LOC101479635
uniprot id: A0A3P9DCL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

106582:mrps17
gene id: 106582:mrps17
uniprot id: A0A3P9DGN4
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

106582:LOC101464068
gene id: 106582:LOC101464068
uniprot id: A0A3P9CEH7
names: Subcellular Location Annotation
messages: Nucleus

106582:use1
gene id: 106582:use1
uniprot id: A0A3P9B3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101478638
gene id: 106582:LOC101478638
uniprot id: A0A3P9C7H3
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101471822
gene id: 106582:LOC101471822
uniprot id: A0A3P9CIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

106582:ddx6
gene id: 106582:ddx6
uniprot id: A0A3P9DDY0
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:LOC101468316
gene id: 106582:LOC101468316
uniprot id: A0A3P9C8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

106582:LOC101486048
gene id: 106582:LOC101486048
uniprot id: A0A3P9BXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101473712
gene id: 106582:LOC101473712
uniprot id: A0A3P9DAI2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

106582:aldh2
gene id: 106582:aldh2
uniprot id: A0A3P9DH85
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:lsm6
gene id: 106582:lsm6
uniprot id: A0A3P9BQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

106582:smarca4
gene id: 106582:smarca4
uniprot id: A0A3P9B5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

106582:LOC101482964
gene id: 106582:LOC101482964
uniprot id: A0A3P9AVS3
names: Similarity
messages: Belongs to the TMEM178 family.

106582:mmachc
gene id: 106582:mmachc
uniprot id: A0A3P9CVE5
names: Similarity
messages: Belongs to the MMACHC family.

106582:LOC101466313
gene id: 106582:LOC101466313
uniprot id: A0A3P9DJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:dock1
gene id: 106582:dock1
uniprot id: A0A3P9AXU3
uniprot id: A0A3P9AXV1
names: Similarity
messages: Belongs to the DOCK family.

106582:tspo
gene id: 106582:tspo
uniprot id: A0A3P9C7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

106582:thap1
gene id: 106582:thap1
uniprot id: A0A3P9AUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

106582:katna1
gene id: 106582:katna1
uniprot id: A0A3P9CF79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

106582:tmem45b
gene id: 106582:tmem45b
uniprot id: A0A3P9CR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

106582:LOC101468476
gene id: 106582:LOC101468476
uniprot id: A0A3P9C8F5
names: Similarity
messages: Belongs to the DPH3 family.

106582:LOC101471591
gene id: 106582:LOC101471591
uniprot id: A0A3P9CCU7
names: Subcellular Location Annotation
messages: Secreted

106582:evpl
gene id: 106582:evpl
uniprot id: A0A3P9AVG6
names: Subcellular Location Annotation
messages: cytoskeleton

106582:ggnbp2
gene id: 106582:ggnbp2
uniprot id: A0A3P9DC28
names: Function
messages: May be involved in spermatogenesis.

106582:cd164
gene id: 106582:cd164
uniprot id: A0A3P9CP70
uniprot id: A0A3P9CP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

106582:gpr34
gene id: 106582:gpr34
uniprot id: A0A3P9CZK3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101476045
gene id: 106582:LOC101476045
uniprot id: A0A3P9BFU0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478732
gene id: 106582:LOC101478732
uniprot id: A0A3P9B5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:LOC101472414
gene id: 106582:LOC101472414
uniprot id: A0A3P9BY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101488106
gene id: 106582:LOC101488106
uniprot id: A0A3P9CK66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

106582:LOC101467308
gene id: 106582:LOC101467308
uniprot id: A0A3P9DPZ3
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

106582:LOC101467056
gene id: 106582:LOC101467056
uniprot id: A0A3P9BWK0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

106582:trmt13
gene id: 106582:trmt13
uniprot id: A0A3P9D148
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

106582:vps51
gene id: 106582:vps51
uniprot id: A0A3P9C795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

106582:LOC101487313
gene id: 106582:LOC101487313
uniprot id: A0A3P9BPB9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101471541
gene id: 106582:LOC101471541
uniprot id: A0A3P9BHZ4
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

106582:LOC101465617
gene id: 106582:LOC101465617
uniprot id: A0A3P9CFQ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101475912
gene id: 106582:LOC101475912
uniprot id: A0A3P9BXF7
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

106582:LOC101469146
gene id: 106582:LOC101469146
uniprot id: A0A3P9BKR6
uniprot id: A0A3P9BKV7
uniprot id: A0A3P9BL27
names: Similarity
messages: Belongs to the DOCK family.

106582:LOC101472746
gene id: 106582:LOC101472746
uniprot id: A0A3P9CHW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101483818
gene id: 106582:LOC101483818
uniprot id: A0A3P9CS02
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106582:nmbr
gene id: 106582:nmbr
uniprot id: A0A3P9C8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101484813
gene id: 106582:LOC101484813
uniprot id: A0A3P9BVY7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101480721
gene id: 106582:LOC101480721
uniprot id: A0A3P9B179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

106582:nudt6
gene id: 106582:nudt6
uniprot id: A0A3P9B215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

106582:LOC101483302
gene id: 106582:LOC101483302
uniprot id: A0A3P9C236
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

106582:plk2
gene id: 106582:plk2
uniprot id: A0A3P9BCV2
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

106582:LOC101465896
gene id: 106582:LOC101465896
uniprot id: A0A3P9C3G4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:chac2
gene id: 106582:chac2
uniprot id: A0A3P9AYQ4
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

106582:LOC101468745
gene id: 106582:LOC101468745
uniprot id: A0A3P9C152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

106582:LOC101471560
gene id: 106582:LOC101471560
uniprot id: A0A3P9CEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

106582:shbg
gene id: 106582:shbg
uniprot id: A0A3P9D333
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC106675409
gene id: 106582:LOC106675409
uniprot id: A0A3P9CXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:nkd2
gene id: 106582:nkd2
uniprot id: A0A3P9CBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

106582:LOC101482051
gene id: 106582:LOC101482051
uniprot id: A0A3P9C9N6
names: Similarity
messages: Belongs to the glutaminase family.

106582:arhgef38
gene id: 106582:arhgef38
uniprot id: A0A3P9CVM7
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack

106582:xpc
gene id: 106582:xpc
uniprot id: A0A3P9D184
names: Similarity
messages: Belongs to the XPC family.

106582:sarm1
gene id: 106582:sarm1
uniprot id: A0A3P9CCI8
names: Similarity
messages: Belongs to the SARM1 family.

106582:LOC101482084
gene id: 106582:LOC101482084
uniprot id: A0A3P9DP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101466232
gene id: 106582:LOC101466232
uniprot id: A0A3P9CW51
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101473859
gene id: 106582:LOC101473859
uniprot id: A0A3P9D499
names: Similarity
messages: Belongs to the cornifelin family.

106582:mrps21
gene id: 106582:mrps21
uniprot id: A0A3P9DL53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

106582:il17ra
gene id: 106582:il17ra
uniprot id: A0A3P9CTF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:slc12a4
gene id: 106582:slc12a4
uniprot id: A0A3P9BHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

106582:lg7h16orf70
gene id: 106582:lg7h16orf70
uniprot id: A0A3P9CIJ5
names: Similarity
messages: Belongs to the PHAF1 family.

106582:kpna6
gene id: 106582:kpna6
uniprot id: A0A3P9ATE0
names: Similarity
messages: Belongs to the importin alpha family.

106582:akirin2
gene id: 106582:akirin2
uniprot id: A0A3P9AYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

106582:emx2
gene id: 106582:emx2
uniprot id: A0A3P9BZZ7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101480084
gene id: 106582:LOC101480084
uniprot id: A0A3P9DLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

106582:rer1
gene id: 106582:rer1
uniprot id: A0A3P9CY60
uniprot id: A0A3P9CYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

106582:aldh4a1
gene id: 106582:aldh4a1
uniprot id: A0A3P9BN85
uniprot id: A0A3P9BNA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:LOC101466637
gene id: 106582:LOC101466637
uniprot id: A0A3P9B4N6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

106582:LOC101480351
gene id: 106582:LOC101480351
uniprot id: A0A3P9CLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:sdhc
gene id: 106582:sdhc
uniprot id: A0A3P9DCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

106582:ppil1
gene id: 106582:ppil1
uniprot id: A0A3P9C693
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:rps2
gene id: 106582:rps2
uniprot id: A0A3P9AT48
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

106582:LOC101472413
gene id: 106582:LOC101472413
uniprot id: A0A3P9CM01
names: Similarity
messages: Belongs to the copine family.

106582:arrdc3
gene id: 106582:arrdc3
uniprot id: A0A3P9C7U3
names: Similarity
messages: Belongs to the arrestin family.

106582:LOC101482824
gene id: 106582:LOC101482824
uniprot id: A0A3P9BVT8
names: Subcellular Location Annotation
messages: Membrane

106582:ccnd1
gene id: 106582:ccnd1
uniprot id: A0A3P9CL13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

106582:LOC101475262
gene id: 106582:LOC101475262
uniprot id: A0A3P9CEC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

106582:thbs2
gene id: 106582:thbs2
uniprot id: A0A3P9BD25
uniprot id: A0A3P9BDE9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ppp1r9a
gene id: 106582:ppp1r9a
uniprot id: A0A3P9BMS1
names: Subcellular Location Annotation
messages: cytoskeleton

106582:LOC101484216
gene id: 106582:LOC101484216
uniprot id: A0A3P9B327
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:pde8a
gene id: 106582:pde8a
uniprot id: A0A3P9BG13
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:ddx27
gene id: 106582:ddx27
uniprot id: A0A3P9BP19
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:cdk5r1
gene id: 106582:cdk5r1
uniprot id: A0A3P9BJX1
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

106582:susd2
gene id: 106582:susd2
uniprot id: A0A3P9CRC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:nim1k
gene id: 106582:nim1k
uniprot id: A0A3P9BH31
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:prickle3
gene id: 106582:prickle3
uniprot id: A0A3P9DLU1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

106582:anapc5
gene id: 106582:anapc5
uniprot id: A0A3P9BAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

106582:LOC101471636
gene id: 106582:LOC101471636
uniprot id: A0A3P9CP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

106582:LOC101483022
gene id: 106582:LOC101483022
uniprot id: A0A3P9AWE8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

106582:myog
gene id: 106582:myog
uniprot id: A0A3P9ATE4
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

106582:LOC101469924
gene id: 106582:LOC101469924
uniprot id: A0A3P9CN48
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:golga5
gene id: 106582:golga5
uniprot id: A0A3P9BXP6
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

106582:pomk
gene id: 106582:pomk
uniprot id: A0A3P9BQH4
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

106582:LOC101473880
gene id: 106582:LOC101473880
uniprot id: A0A3P9BCT4
names: Subcellular Location Annotation
messages: Nucleus

106582:ggcx
gene id: 106582:ggcx
uniprot id: A0A3P9CR05
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Membrane

106582:LOC101487015
gene id: 106582:LOC101487015
uniprot id: A0A3P9C523
names: Subcellular Location Annotation
messages: Nucleus

106582:prkar1b
gene id: 106582:prkar1b
uniprot id: A0A3P9B6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

106582:en2
gene id: 106582:en2
uniprot id: A0A3P9D5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

106582:LOC101473580
gene id: 106582:LOC101473580
uniprot id: A0A3P9CD10
names: Similarity
messages: Belongs to the FAX family.

106582:LOC101478784
gene id: 106582:LOC101478784
uniprot id: A0A3P9B500
names: Similarity
messages: Belongs to the threonine aldolase family.

106582:csnk2a2
gene id: 106582:csnk2a2
uniprot id: A0A3P9BTQ2
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:kcnj8
gene id: 106582:kcnj8
uniprot id: A0A3P9D328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:lsm8
gene id: 106582:lsm8
uniprot id: A0A3P9CTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

106582:tada1
gene id: 106582:tada1
uniprot id: A0A3P9BQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

106582:LOC101474759
gene id: 106582:LOC101474759
uniprot id: A0A3P9BH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

106582:nkiras2
gene id: 106582:nkiras2
uniprot id: A0A3P9D8T2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

106582:LOC101479319
gene id: 106582:LOC101479319
uniprot id: A0A3P9B3F5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

106582:gnrh1
gene id: 106582:gnrh1
uniprot id: A0A3P9BJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted

106582:LOC101467268
gene id: 106582:LOC101467268
uniprot id: A0A3P9CIX5
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

106582:ppip5k1
gene id: 106582:ppip5k1
uniprot id: A0A3P9CGK6
uniprot id: A0A3P9CGQ2
uniprot id: A0A3P9CGT0
uniprot id: A0A3P9CHF1
uniprot id: A0A3P9CHI3
uniprot id: A0A3P9CIA6
uniprot id: A0A3P9CIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

106582:LOC101487312
gene id: 106582:LOC101487312
uniprot id: A0A3P9CI08
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

106582:LOC101464472
gene id: 106582:LOC101464472
uniprot id: A0A3P9CMS4
uniprot id: A0A3P9CNL9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

106582:manba
gene id: 106582:manba
uniprot id: A0A3P9C1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

106582:ncapg
gene id: 106582:ncapg
uniprot id: A0A3P9DBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

106582:wdfy1
gene id: 106582:wdfy1
uniprot id: A0A3P9B3B9
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

106582:LOC101473510
gene id: 106582:LOC101473510
uniprot id: A0A3P9CD94
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

106582:LOC101474040
gene id: 106582:LOC101474040
uniprot id: A0A3P9BHB2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101464585
gene id: 106582:LOC101464585
uniprot id: A0A3P9AZD7
names: Similarity
messages: Belongs to the complex I LYR family.

106582:fam135a
gene id: 106582:fam135a
uniprot id: A0A3P9BC44
names: Similarity
messages: Belongs to the FAM135 family.

106582:LOC101465858
gene id: 106582:LOC101465858
uniprot id: A0A3P9B8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

106582:mul1
gene id: 106582:mul1
uniprot id: A0A3P9D9S0
names: Subcellular Location Annotation
messages: Membrane

106582:ppp2r3c
gene id: 106582:ppp2r3c
uniprot id: A0A3P9BLT9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101473264
gene id: 106582:LOC101473264
uniprot id: A0A3P9B8Z7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101471374
gene id: 106582:LOC101471374
uniprot id: A0A3P9B5U0
names: Subcellular Location Annotation
messages: Nucleus

106582:rpl8
gene id: 106582:rpl8
uniprot id: A0A3P9D2G0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

106582:fam19a2
gene id: 106582:fam19a2
uniprot id: A0A3P9CQP3
names: Similarity
messages: Belongs to the TAFA family.

106582:LOC101466548
gene id: 106582:LOC101466548
uniprot id: A0A3P9BRJ7
names: Similarity
messages: Belongs to the DIP2 family.

106582:LOC101480437
gene id: 106582:LOC101480437
uniprot id: A0A3P9BVJ0
names: Similarity
messages: Belongs to the centrin family.

106582:ndufaf4
gene id: 106582:ndufaf4
uniprot id: A0A3P9CGP9
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

106582:mfsd10
gene id: 106582:mfsd10
uniprot id: A0A3P9C758
names: Subcellular Location Annotation
messages: Membrane

106582:elp4
gene id: 106582:elp4
uniprot id: A0A3P9C144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101482523
gene id: 106582:LOC101482523
uniprot id: A0A3P9C0B7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

106582:atxn1l
gene id: 106582:atxn1l
uniprot id: A0A3P9C9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

106582:LOC101478097
gene id: 106582:LOC101478097
uniprot id: A0A3P9DLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

106582:tmem234
gene id: 106582:tmem234
uniprot id: A0A3P9B7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

106582:thop1
gene id: 106582:thop1
uniprot id: A0A3P9B828
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

106582:LOC101467265
gene id: 106582:LOC101467265
uniprot id: A0A3P9ARS4
names: Similarity
messages: Belongs to the OSBP family.

106582:elp1
gene id: 106582:elp1
uniprot id: A0A3P9BHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

106582:gtf2a2
gene id: 106582:gtf2a2
uniprot id: A0A3P9B3N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

106582:vars2
gene id: 106582:vars2
uniprot id: A0A3P9CMQ6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:LOC101485028
gene id: 106582:LOC101485028
uniprot id: A0A3P9DHA4
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

106582:uhrf1
gene id: 106582:uhrf1
uniprot id: A0A3P9CL62
names: Subcellular Location Annotation
messages: Nucleus

106582:sparc
gene id: 106582:sparc
uniprot id: A0A3P9B787
names: Similarity
messages: Belongs to the SPARC family.

106582:syndig1l
gene id: 106582:syndig1l
uniprot id: A0A3P9BQI4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:gdpgp1
gene id: 106582:gdpgp1
uniprot id: A0A3P9CN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

106582:timp4
gene id: 106582:timp4
uniprot id: A0A3P9C8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

106582:tbpl1
gene id: 106582:tbpl1
uniprot id: A0A3P9CFR8
names: Similarity
messages: Belongs to the TBP family.

106582:LOC101465907
gene id: 106582:LOC101465907
uniprot id: A0A3P9CL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101469080
gene id: 106582:LOC101469080
uniprot id: A0A3P9CXV4
names: Subcellular Location Annotation
messages: Membrane

106582:fam120a
gene id: 106582:fam120a
uniprot id: A0A3P9BFF1
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

106582:enoph1
gene id: 106582:enoph1
uniprot id: A0A3P9BJ30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

106582:LOC101487158
gene id: 106582:LOC101487158
uniprot id: A0A3P9CUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

106582:LOC101478951
gene id: 106582:LOC101478951
uniprot id: A0A3P9BKS7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:trappc5
gene id: 106582:trappc5
uniprot id: A0A3P9ARN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

106582:LOC101469289
gene id: 106582:LOC101469289
uniprot id: A0A3P9DQU3
names: Subcellular Location Annotation
messages: Nucleus

106582:ddx4
gene id: 106582:ddx4
uniprot id: A0A3P9CU78
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:ftsj1
gene id: 106582:ftsj1
uniprot id: A0A3P9D6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

106582:LOC101482487
gene id: 106582:LOC101482487
uniprot id: A0A3P9B250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

106582:kcng4
gene id: 106582:kcng4
uniprot id: A0A3P9CJT8
names: Subcellular Location Annotation
messages: Membrane

106582:slc37a2
gene id: 106582:slc37a2
uniprot id: A0A3P9BTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

106582:meox1
gene id: 106582:meox1
uniprot id: A0A3P9BIU8
names: Subcellular Location Annotation
messages: Nucleus

106582:tram2
gene id: 106582:tram2
uniprot id: A0A3P9CR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

106582:larp7
gene id: 106582:larp7
uniprot id: A0A3P9AYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

106582:ano5
gene id: 106582:ano5
uniprot id: A0A3P9AY50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:lrrc8a
gene id: 106582:lrrc8a
uniprot id: A0A3P9B134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

106582:LOC101484592
gene id: 106582:LOC101484592
uniprot id: A0A3P9DFM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

106582:tmem170a
gene id: 106582:tmem170a
uniprot id: A0A3P9D851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

106582:hoxa5
gene id: 106582:hoxa5
uniprot id: A0A3P9BU75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:LOC101468603
gene id: 106582:LOC101468603
uniprot id: A0A3P9C9P5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

106582:il10
gene id: 106582:il10
uniprot id: A0A3P9AUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

106582:gucy1b1
gene id: 106582:gucy1b1
uniprot id: A0A3P9D7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

106582:adora2a
gene id: 106582:adora2a
uniprot id: A0A3P9AYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

106582:LOC101482601
gene id: 106582:LOC101482601
uniprot id: A0A3P9BE17
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

106582:LOC101481991
gene id: 106582:LOC101481991
uniprot id: A0A3P9CC74
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101473596
gene id: 106582:LOC101473596
uniprot id: A0A3P9AZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

106582:LOC101480448
gene id: 106582:LOC101480448
uniprot id: A0A3P9BEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

106582:LOC101471148
gene id: 106582:LOC101471148
uniprot id: A0A3P9AXL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:tmem9b
gene id: 106582:tmem9b
uniprot id: A0A3P9CD65
names: Similarity
messages: Belongs to the TMEM9 family.

106582:LOC101481404
gene id: 106582:LOC101481404
uniprot id: A0A3P9C2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

106582:LOC101484067
gene id: 106582:LOC101484067
uniprot id: A0A3P9B6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

106582:LOC101466985
gene id: 106582:LOC101466985
uniprot id: A0A3P9DS99
names: Similarity
messages: Belongs to the dickkopf family.

106582:LOC101463772
gene id: 106582:LOC101463772
uniprot id: A0A3P9CHM0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

106582:LOC101487969
gene id: 106582:LOC101487969
uniprot id: A0A3P9BKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

106582:LOC101487021
gene id: 106582:LOC101487021
uniprot id: A0A3P9BSZ8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101472257
gene id: 106582:LOC101472257
uniprot id: A0A3P9BKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

106582:ppp3r1
gene id: 106582:ppp3r1
uniprot id: A0A3P9DQD4
uniprot id: A0A3P9DQX0
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

106582:LOC101464044
gene id: 106582:LOC101464044
uniprot id: A0A3P9CZB1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

106582:polr2f
gene id: 106582:polr2f
uniprot id: A0A3P9BC33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

106582:sod2
gene id: 106582:sod2
uniprot id: A0A3P9CPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

106582:LOC101464836
gene id: 106582:LOC101464836
uniprot id: A0A3P9DJ50
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101488125
gene id: 106582:LOC101488125
uniprot id: A0A3P9DCF2
names: Subcellular Location Annotation
messages: Membrane

106582:vdac1
gene id: 106582:vdac1
uniprot id: A0A3P9BNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

106582:abl1
gene id: 106582:abl1
uniprot id: A0A3P9CRZ9
uniprot id: A0A3P9CS06
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:LOC101477257
gene id: 106582:LOC101477257
uniprot id: A0A3P9CS39
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

106582:LOC101467586
gene id: 106582:LOC101467586
uniprot id: A0A3P9D8G2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

106582:dnajc16
gene id: 106582:dnajc16
uniprot id: A0A3P9D207
names: Subcellular Location Annotation
messages: Membrane

106582:rtcb
gene id: 106582:rtcb
uniprot id: A0A3P9CU93
uniprot id: A0A3P9CU97
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

106582:LOC101478944
gene id: 106582:LOC101478944
uniprot id: A0A3P9CF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

106582:vps72
gene id: 106582:vps72
uniprot id: A0A3P9DM14
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

106582:spr
gene id: 106582:spr
uniprot id: A0A3P9DAC8
names: Similarity
messages: Belongs to the sepiapterin reductase family.

106582:LOC101464175
gene id: 106582:LOC101464175
uniprot id: A0A3P9CH49
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:abcg8
gene id: 106582:abcg8
uniprot id: A0A3P9DR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

106582:LOC101477745
gene id: 106582:LOC101477745
uniprot id: A0A3P9DQV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

106582:mnx1
gene id: 106582:mnx1
uniprot id: A0A3P9AS54
names: Subcellular Location Annotation
messages: Nucleus

106582:fam3a
gene id: 106582:fam3a
uniprot id: A0A3P9DP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

106582:ano8
gene id: 106582:ano8
uniprot id: A0A3P9CSZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101477800
gene id: 106582:LOC101477800
uniprot id: A0A3P9B3W0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

106582:LOC101474940
gene id: 106582:LOC101474940
uniprot id: A0A3P9BN98
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

106582:LOC101467495
gene id: 106582:LOC101467495
uniprot id: A0A3P9B4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

106582:smc4
gene id: 106582:smc4
uniprot id: A0A3P9ARV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

106582:cblb
gene id: 106582:cblb
uniprot id: A0A3P9DBJ4
uniprot id: A0A3P9DBK2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

106582:LOC101474240
gene id: 106582:LOC101474240
uniprot id: A0A3P9BM00
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:hoxc13
gene id: 106582:hoxc13
uniprot id: A0A3P9DQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:anxa10
gene id: 106582:anxa10
uniprot id: A0A3P9BLY5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

106582:LOC101475445
gene id: 106582:LOC101475445
uniprot id: A0A3P9D7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

106582:vasn
gene id: 106582:vasn
uniprot id: A0A3P9B823
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:rpn1
gene id: 106582:rpn1
uniprot id: A0A3P9BXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

106582:trdn
gene id: 106582:trdn
uniprot id: A0A3P9C6S6
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

106582:mief1
gene id: 106582:mief1
uniprot id: A0A3P9BGR7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

106582:dlx2
gene id: 106582:dlx2
uniprot id: A0A3P9BAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

106582:med19
gene id: 106582:med19
uniprot id: A0A3P9B1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:sema5b
gene id: 106582:sema5b
uniprot id: A0A3P9CST5
uniprot id: A0A3P9CSX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101479903
gene id: 106582:LOC101479903
uniprot id: A0A3P9AX62
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

106582:LOC101464929
gene id: 106582:LOC101464929
uniprot id: A0A3P9CL69
names: Similarity
messages: Belongs to the GDNFR family.

106582:LOC101481172
gene id: 106582:LOC101481172
uniprot id: A0A3P9DDW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ca8
gene id: 106582:ca8
uniprot id: A0A3P9BWL6
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

106582:LOC101470299
gene id: 106582:LOC101470299
uniprot id: A0A3P9DNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

106582:hint3
gene id: 106582:hint3
uniprot id: A0A3P9AXW1
names: Similarity
messages: Belongs to the HINT family.

106582:cenpk
gene id: 106582:cenpk
uniprot id: A0A3P9BNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

106582:LOC101478172
gene id: 106582:LOC101478172
uniprot id: A0A3P9ASF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

106582:LOC101474223
gene id: 106582:LOC101474223
uniprot id: A0A3P9BBK0
names: Subcellular Location Annotation
messages: Nucleus

106582:dbx1
gene id: 106582:dbx1
uniprot id: A0A3P9CB08
names: Subcellular Location Annotation
messages: Nucleus

106582:aqp9
gene id: 106582:aqp9
uniprot id: A0A3P9C8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:LOC101481487
gene id: 106582:LOC101481487
uniprot id: A0A3P9CRM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:smim7
gene id: 106582:smim7
uniprot id: A0A3P9CKK7
names: Similarity
messages: Belongs to the SMIM7 family.

106582:LOC101470284
gene id: 106582:LOC101470284
uniprot id: A0A3P9DLM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

106582:stard3
gene id: 106582:stard3
uniprot id: A0A3P9D8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

106582:cmc4
gene id: 106582:cmc4
uniprot id: A0A3P9CTS7
names: Similarity
messages: Belongs to the CMC4 family.

106582:LOC101478059
gene id: 106582:LOC101478059
uniprot id: A0A3P9AYE1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

106582:phox2b
gene id: 106582:phox2b
uniprot id: A0A3P9B141
names: Subcellular Location Annotation
messages: Nucleus

106582:tmem192
gene id: 106582:tmem192
uniprot id: A0A3P9BMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

106582:LOC101471241
gene id: 106582:LOC101471241
uniprot id: A0A3P9C2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

106582:LOC101475964
gene id: 106582:LOC101475964
uniprot id: A0A3P9DNP9
names: Similarity
messages: Belongs to the TAFA family.

106582:nfkb2
gene id: 106582:nfkb2
uniprot id: A0A3P9B6G3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:islr2
gene id: 106582:islr2
uniprot id: A0A3P9D6P5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101487814
gene id: 106582:LOC101487814
uniprot id: A0A3P9DR38
names: Similarity
messages: Belongs to the phospholipase D family.

106582:LOC101473407
gene id: 106582:LOC101473407
uniprot id: A0A3P9DKU9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:bnip3
gene id: 106582:bnip3
uniprot id: A0A3P9DRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

106582:myoc
gene id: 106582:myoc
uniprot id: A0A3P9CV73
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

106582:gys1
gene id: 106582:gys1
uniprot id: A0A3P9BWZ0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

106582:zfp36l2
gene id: 106582:zfp36l2
uniprot id: A0A3P9CQB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

106582:c1d
gene id: 106582:c1d
uniprot id: A0A3P9DQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

106582:mmp9
gene id: 106582:mmp9
uniprot id: A0A3P9BF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

106582:LOC101473671
gene id: 106582:LOC101473671
uniprot id: A0A3P9DK45
names: Similarity
messages: Belongs to the TGF-beta family.

106582:ndp
gene id: 106582:ndp
uniprot id: A0A3P9D0H9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:rhbdl3
gene id: 106582:rhbdl3
uniprot id: A0A3P9DBI0
uniprot id: A0A3P9DD33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

106582:trmt112
gene id: 106582:trmt112
uniprot id: A0A3P9B990
names: Similarity
messages: Belongs to the TRM112 family.

106582:clstn1
gene id: 106582:clstn1
uniprot id: A0A3P9C6G9
uniprot id: A0A3P9C720
uniprot id: A0A3P9C740
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101466659
gene id: 106582:LOC101466659
uniprot id: A0A3P9AYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

106582:LOC101477464
gene id: 106582:LOC101477464
uniprot id: A0A3P9D5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

106582:LOC101482621
gene id: 106582:LOC101482621
uniprot id: A0A3P9D0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

106582:LOC101481681
gene id: 106582:LOC101481681
uniprot id: A0A3P9BXA7
names: Subcellular Location Annotation
messages: Nucleus

106582:frg1
gene id: 106582:frg1
uniprot id: A0A3P9BJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

106582:LOC101465027
gene id: 106582:LOC101465027
uniprot id: A0A3P9CHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101471831
gene id: 106582:LOC101471831
uniprot id: A0A3P9BGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

106582:kcnk13
gene id: 106582:kcnk13
uniprot id: A0A3P9BEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:LOC101485050
gene id: 106582:LOC101485050
uniprot id: A0A3P9BD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

106582:LOC101476478
gene id: 106582:LOC101476478
uniprot id: A0A3P9BX78
names: Similarity
messages: Belongs to the EVA1 family.

106582:LOC101471686
gene id: 106582:LOC101471686
uniprot id: A0A3P9DDH0
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

106582:LOC101485924
gene id: 106582:LOC101485924
uniprot id: A0A3P9DQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:xpot
gene id: 106582:xpot
uniprot id: A0A3P9CSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

106582:LOC101468811
gene id: 106582:LOC101468811
uniprot id: A0A3P9D8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

106582:dnaaf4
gene id: 106582:dnaaf4
uniprot id: A0A3P9D7V5
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

106582:stx12
gene id: 106582:stx12
uniprot id: A0A3P9CNR0
names: Similarity
messages: Belongs to the syntaxin family.

106582:ost4
gene id: 106582:ost4
uniprot id: A0A3P9BUN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:lyrm4
gene id: 106582:lyrm4
uniprot id: A0A3P9CXS0
names: Similarity
messages: Belongs to the complex I LYR family.

106582:LOC101484165
gene id: 106582:LOC101484165
uniprot id: A0A3P9BTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

106582:LOC101479627
gene id: 106582:LOC101479627
uniprot id: A0A3P9CY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

106582:gsr
gene id: 106582:gsr
uniprot id: A0A3P9BQ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

106582:aig1
gene id: 106582:aig1
uniprot id: A0A3P9C537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

106582:LOC101484958
gene id: 106582:LOC101484958
uniprot id: A0A3P9C208
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

106582:LOC101470609
gene id: 106582:LOC101470609
uniprot id: A0A3P9AUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:crygn
gene id: 106582:crygn
uniprot id: A0A3P9CZ68
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101486503
gene id: 106582:LOC101486503
uniprot id: A0A3P9DBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

106582:mrpl41
gene id: 106582:mrpl41
uniprot id: A0A3P9B5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

106582:ndufa8
gene id: 106582:ndufa8
uniprot id: A0A3P9CNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

106582:LOC101481807
gene id: 106582:LOC101481807
uniprot id: A0A3P9DKU6
uniprot id: A0A3P9DKW3
uniprot id: A0A3P9DKY0
uniprot id: A0A3P9DLD3
uniprot id: A0A3P9DLE8
names: Subcellular Location Annotation
messages: cytoskeleton

106582:btaf1
gene id: 106582:btaf1
uniprot id: A0A3P9C1K5
names: Subcellular Location Annotation
messages: Nucleus

106582:prkcq
gene id: 106582:prkcq
uniprot id: A0A3P9AS63
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

106582:urod
gene id: 106582:urod
uniprot id: A0A3P9CB65
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

106582:sbds
gene id: 106582:sbds
uniprot id: A0A3P9DF13
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

106582:LOC101482700
gene id: 106582:LOC101482700
uniprot id: A0A3P9B3V9
names: Similarity
messages: Belongs to the splicing factor SR family.

106582:ap3s1
gene id: 106582:ap3s1
uniprot id: A0A3P9BPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

106582:LOC101485767
gene id: 106582:LOC101485767
uniprot id: A0A3P9CA58
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101468487
gene id: 106582:LOC101468487
uniprot id: A0A3P9B651
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

106582:LOC101484659
gene id: 106582:LOC101484659
uniprot id: A0A3P9DJH6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

106582:LOC101483923
gene id: 106582:LOC101483923
uniprot id: A0A3P9DP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

106582:ubiad1
gene id: 106582:ubiad1
uniprot id: A0A3P9D3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

106582:LOC101475623
gene id: 106582:LOC101475623
uniprot id: A0A3P9DM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

106582:sgsm3
gene id: 106582:sgsm3
uniprot id: A0A3P9C2X9
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

106582:psmd6
gene id: 106582:psmd6
uniprot id: A0A3P9C195
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

106582:LOC101474669
gene id: 106582:LOC101474669
uniprot id: A0A3P9CW13
names: Similarity
messages: Belongs to the PDCD4 family.

106582:gatc
gene id: 106582:gatc
uniprot id: A0A3P9CHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

106582:wnt10b
gene id: 106582:wnt10b
uniprot id: A0A3P9DQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:cercam
gene id: 106582:cercam
uniprot id: A0A3P9CLL3
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

106582:tubgcp5
gene id: 106582:tubgcp5
uniprot id: A0A3P9D0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

106582:sema4c
gene id: 106582:sema4c
uniprot id: A0A3P9AUI1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ada
gene id: 106582:ada
uniprot id: A0A3P9D9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

106582:phf10
gene id: 106582:phf10
uniprot id: A0A3P9BY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

106582:unc5a
gene id: 106582:unc5a
uniprot id: A0A3P9BTG7
uniprot id: A0A3P9BTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

106582:nr3c1
gene id: 106582:nr3c1
uniprot id: A0A3P9B1D6
uniprot id: A0A3P9B1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

106582:kcnk3
gene id: 106582:kcnk3
uniprot id: A0A3P9AUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:LOC101479335
gene id: 106582:LOC101479335
uniprot id: A0A3P9CTA8
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

106582:LOC101468133
gene id: 106582:LOC101468133
uniprot id: A0A3P9CI73
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478846
gene id: 106582:LOC101478846
uniprot id: A0A3P9BWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101465854
gene id: 106582:LOC101465854
uniprot id: A0A3P9B4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

106582:rtn1
gene id: 106582:rtn1
uniprot id: A0A3P9BJY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101468172
gene id: 106582:LOC101468172
uniprot id: A0A3P9BB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

106582:ltv1
gene id: 106582:ltv1
uniprot id: A0A3P9BAI3
names: Similarity
messages: Belongs to the LTV1 family.

106582:pgk1
gene id: 106582:pgk1
uniprot id: A0A3P9BSJ1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

106582:ears2
gene id: 106582:ears2
uniprot id: A0A3P9C942
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

106582:chst2
gene id: 106582:chst2
uniprot id: A0A3P9D5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:anxa3
gene id: 106582:anxa3
uniprot id: A0A3P9CYS5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

106582:axin1
gene id: 106582:axin1
uniprot id: A0A3P9D7W5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

106582:LOC101466547
gene id: 106582:LOC101466547
uniprot id: A0A3P9DDL2
names: Subcellular Location Annotation
messages: Membrane

106582:zdhhc9
gene id: 106582:zdhhc9
uniprot id: A0A3P9BJ51
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101475127
gene id: 106582:LOC101475127
uniprot id: A0A3P9BTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

106582:ptpn14
gene id: 106582:ptpn14
uniprot id: A0A3P9CL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

106582:lmln
gene id: 106582:lmln
uniprot id: A0A3P9CZ67
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

106582:gapdh
gene id: 106582:gapdh
uniprot id: A0A3P9CN65
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

106582:LOC101464672
gene id: 106582:LOC101464672
uniprot id: A0A3P9CHE2
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101482088
gene id: 106582:LOC101482088
uniprot id: A0A3P9BYP2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101474879
gene id: 106582:LOC101474879
uniprot id: A0A3P9BKV8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

106582:calhm1
gene id: 106582:calhm1
uniprot id: A0A3P9BQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

106582:slc6a1
gene id: 106582:slc6a1
uniprot id: A0A3P9C8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101475107
gene id: 106582:LOC101475107
uniprot id: A0A3P9CU54
names: Similarity
messages: Belongs to the peptidase A1 family.

106582:LOC101465915
gene id: 106582:LOC101465915
uniprot id: A0A3P9BD65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

106582:tmem38a
gene id: 106582:tmem38a
uniprot id: A0A3P9CKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

106582:eloa
gene id: 106582:eloa
uniprot id: A0A3P9DKL7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101480709
gene id: 106582:LOC101480709
uniprot id: A0A3P9DMQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101481297
gene id: 106582:LOC101481297
uniprot id: A0A3P9DB32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:abat
gene id: 106582:abat
uniprot id: A0A3P9AX69
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

106582:LOC101488036
gene id: 106582:LOC101488036
uniprot id: A0A3P9DRZ7
names: Subcellular Location Annotation
messages: Nucleus

106582:casd1
gene id: 106582:casd1
uniprot id: A0A3P9BM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

106582:tecpr1
gene id: 106582:tecpr1
uniprot id: A0A3P9BN30
names: Similarity
messages: Belongs to the TECPR1 family.

106582:uxs1
gene id: 106582:uxs1
uniprot id: A0A3P9D5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

106582:LOC101480594
gene id: 106582:LOC101480594
uniprot id: A0A3P9BF04
uniprot id: A0A3P9BFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

106582:ptch1
gene id: 106582:ptch1
uniprot id: A0A3P9BF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

106582:cct7
gene id: 106582:cct7
uniprot id: A0A3P9B5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

106582:nkx3-2
gene id: 106582:nkx3-2
uniprot id: A0A3P9BQP6
names: Subcellular Location Annotation
messages: Nucleus

106582:eif2b2
gene id: 106582:eif2b2
uniprot id: A0A3P9CI38
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

106582:LOC101468244
gene id: 106582:LOC101468244
uniprot id: A0A3P9CQC9
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

106582:LOC101487394
gene id: 106582:LOC101487394
uniprot id: A0A3P9DMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:vps36
gene id: 106582:vps36
uniprot id: A0A3P9CV76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

106582:LOC101486254
gene id: 106582:LOC101486254
uniprot id: A0A3P9CH23
names: Similarity
messages: Belongs to the phospholipase D family.

106582:LOC101487486
gene id: 106582:LOC101487486
uniprot id: A0A3P9CLY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101482271
gene id: 106582:LOC101482271
uniprot id: A0A3P9BVK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101465548
gene id: 106582:LOC101465548
uniprot id: A0A3P9DPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

106582:wdr12
gene id: 106582:wdr12
uniprot id: A0A3P9ATI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

106582:ska3
gene id: 106582:ska3
uniprot id: A0A3P9CV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

106582:mrps25
gene id: 106582:mrps25
uniprot id: A0A3P9ARD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

106582:kif4a
gene id: 106582:kif4a
uniprot id: A0A3P9C5S8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:LOC101465291
gene id: 106582:LOC101465291
uniprot id: A0A3P9CBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

106582:camsap3
gene id: 106582:camsap3
uniprot id: A0A3P9CRK5
uniprot id: A0A3P9CRM2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

106582:cxadr
gene id: 106582:cxadr
uniprot id: A0A3P9D9H9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101473393
gene id: 106582:LOC101473393
uniprot id: A0A3P9CUT4
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

106582:aimp2
gene id: 106582:aimp2
uniprot id: A0A3P9C676
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

106582:efs
gene id: 106582:efs
uniprot id: A0A3P9D0I0
names: Similarity
messages: Belongs to the CAS family.

106582:LOC101464622
gene id: 106582:LOC101464622
uniprot id: A0A3P9B8C6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

106582:LOC101479612
gene id: 106582:LOC101479612
uniprot id: A0A3P9D8H6
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101482689
gene id: 106582:LOC101482689
uniprot id: F8TJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

106582:snph
gene id: 106582:snph
uniprot id: A0A3P9D4E9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480478
gene id: 106582:LOC101480478
uniprot id: A0A3P9CD37
uniprot id: A0A3P9CDE2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

106582:jun
gene id: 106582:jun
uniprot id: A0A3P9BQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

106582:trpm7
gene id: 106582:trpm7
uniprot id: A0A3P9BM41
uniprot id: A0A3P9BM77
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

106582:LOC101482974
gene id: 106582:LOC101482974
uniprot id: A0A3P9BK30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

106582:LOC101469966
gene id: 106582:LOC101469966
uniprot id: A0A3P9BB22
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101485880
gene id: 106582:LOC101485880
uniprot id: A0A3P9DKC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101476181
gene id: 106582:LOC101476181
uniprot id: A0A3P9BZR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

106582:ap3s2
gene id: 106582:ap3s2
uniprot id: A0A3P9BBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

106582:chpf2
gene id: 106582:chpf2
uniprot id: A0A3P9CS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

106582:LOC101464368
gene id: 106582:LOC101464368
uniprot id: A0A3P9CCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

106582:naa25
gene id: 106582:naa25
uniprot id: A0A3P9BMN6
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

106582:sap130
gene id: 106582:sap130
uniprot id: A0A3P9BPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

106582:nsfl1c
gene id: 106582:nsfl1c
uniprot id: A0A3P9D5U8
names: Subcellular Location Annotation
messages: Golgi stack

106582:nipal2
gene id: 106582:nipal2
uniprot id: A0A3P9DI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

106582:LOC101478333
gene id: 106582:LOC101478333
uniprot id: A0A3P9AYA0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:LOC101484715
gene id: 106582:LOC101484715
uniprot id: A0A3P9BG24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC105941156
gene id: 106582:LOC105941156
uniprot id: A0A3P9BJN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:psmc5
gene id: 106582:psmc5
uniprot id: A0A3P9CCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

106582:unc119b
gene id: 106582:unc119b
uniprot id: A0A3P9ARR6
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

106582:cfl2
gene id: 106582:cfl2
uniprot id: A0A3P9CKU8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

106582:sfrp5
gene id: 106582:sfrp5
uniprot id: A0A3P9DRX8
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101480473
gene id: 106582:LOC101480473
uniprot id: A0A3P9BWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101484045
gene id: 106582:LOC101484045
uniprot id: A0A3P9DS23
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

106582:fgf14
gene id: 106582:fgf14
uniprot id: A0A3P9D2X2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:cdc42bpb
gene id: 106582:cdc42bpb
uniprot id: A0A3P9CD27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

106582:leo1
gene id: 106582:leo1
uniprot id: A0A3P9BHG5
names: Similarity
messages: Belongs to the LEO1 family.

106582:prpf19
gene id: 106582:prpf19
uniprot id: A0A3P9C6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

106582:sept10
gene id: 106582:sept10
uniprot id: A0A3P9BVD2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

106582:LOC101487546
gene id: 106582:LOC101487546
uniprot id: A0A3P9BDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101470037
gene id: 106582:LOC101470037
uniprot id: A0A3P9C9X3
names: Subcellular Location Annotation
messages: Membrane

106582:kif13a
gene id: 106582:kif13a
uniprot id: A0A3P9CAF4
uniprot id: A0A3P9CAV3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:LOC101464285
gene id: 106582:LOC101464285
uniprot id: A0A3P9CKQ5
uniprot id: A0A3P9CKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

106582:me1
gene id: 106582:me1
uniprot id: A0A3P9C0G7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

106582:dolk
gene id: 106582:dolk
uniprot id: A0A3P9B0Z3
names: Similarity
messages: Belongs to the polyprenol kinase family.

106582:gata4
gene id: 106582:gata4
uniprot id: A0A3P9CIV0
names: Subcellular Location Annotation
messages: Nucleus

106582:e2f3
gene id: 106582:e2f3
uniprot id: A0A3P9DJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

106582:snta1
gene id: 106582:snta1
uniprot id: A0A3P9BAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

106582:LOC101475922
gene id: 106582:LOC101475922
uniprot id: A0A3P9B776
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

106582:hvcn1
gene id: 106582:hvcn1
uniprot id: A0A3P9CMJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

106582:khdrbs2
gene id: 106582:khdrbs2
uniprot id: A0A3P9BB76
names: Similarity
messages: Belongs to the KHDRBS family.

106582:slc1a1
gene id: 106582:slc1a1
uniprot id: A0A3P9C4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

106582:LOC101464554
gene id: 106582:LOC101464554
uniprot id: A0A3P9CJ97
names: Similarity
messages: Belongs to the BRINP family.

106582:LOC101467407
gene id: 106582:LOC101467407
uniprot id: A0A3P9CR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

106582:ipo11
gene id: 106582:ipo11
uniprot id: A0A3P9BFS3
names: Subcellular Location Annotation
messages: Cytoplasm

106582:scara5
gene id: 106582:scara5
uniprot id: A0A3P9BB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

106582:cript
gene id: 106582:cript
uniprot id: A0A3P9B033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

106582:LOC101473241
gene id: 106582:LOC101473241
uniprot id: A0A3P9AUI2
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

106582:tamm41
gene id: 106582:tamm41
uniprot id: A0A3P9C904
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

106582:LOC101481441
gene id: 106582:LOC101481441
uniprot id: A0A3P9B9D7
uniprot id: A0A3P9B9L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101485094
gene id: 106582:LOC101485094
uniprot id: A0A3P9BHY2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

106582:pou6f1
gene id: 106582:pou6f1
uniprot id: A0A3P9DMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:b9d1
gene id: 106582:b9d1
uniprot id: A0A3P9BM24
names: Subcellular Location Annotation
messages: cilium basal body

106582:LOC101469506
gene id: 106582:LOC101469506
uniprot id: A0A3P9BCU0
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:ndnf
gene id: 106582:ndnf
uniprot id: A0A3P9CZ79
names: Subcellular Location Annotation
messages: Secreted

106582:LOC101485669
gene id: 106582:LOC101485669
uniprot id: A0A3P9AU28
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

106582:LOC101487216
gene id: 106582:LOC101487216
uniprot id: A0A3P9CGT9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

106582:cdk5rap3
gene id: 106582:cdk5rap3
uniprot id: A0A3P9BLD0
names: Similarity
messages: Belongs to the CDK5RAP3 family.

106582:LOC101480417
gene id: 106582:LOC101480417
uniprot id: A0A3P9DMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

106582:slc8a3
gene id: 106582:slc8a3
uniprot id: A0A3P9BW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

106582:gosr2
gene id: 106582:gosr2
uniprot id: A0A3P9D873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

106582:doc2b
gene id: 106582:doc2b
uniprot id: A0A3P9BYZ2
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101475325
gene id: 106582:LOC101475325
uniprot id: A0A3P9B5F4
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:etv6
gene id: 106582:etv6
uniprot id: A0A3P9CPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101486276
gene id: 106582:LOC101486276
uniprot id: A0A3P9C0U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

106582:fstl5
gene id: 106582:fstl5
uniprot id: A0A3P9AZ17
names: Subcellular Location Annotation
messages: Membrane

106582:calcrl
gene id: 106582:calcrl
uniprot id: A0A3P9CCJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

106582:aqr
gene id: 106582:aqr
uniprot id: A0A3P9AZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

106582:LOC101467164
gene id: 106582:LOC101467164
uniprot id: A0A3P9AY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

106582:manbal
gene id: 106582:manbal
uniprot id: A0A3P9B5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

106582:LOC101474823
gene id: 106582:LOC101474823
uniprot id: A0A3P9CJD8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:cryba4
gene id: 106582:cryba4
uniprot id: A0A3P9C1M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

106582:LOC101478711
gene id: 106582:LOC101478711
uniprot id: A0A3P9CDU8
names: Similarity
messages: Belongs to the glutamine synthetase family.

106582:LOC101470232
gene id: 106582:LOC101470232
uniprot id: A0A3P9BJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

106582:emc6
gene id: 106582:emc6
uniprot id: A0A3P9ASL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101473491
gene id: 106582:LOC101473491
uniprot id: A0A3P9CRJ6
names: Similarity
messages: Belongs to the FHIP family.

106582:dpm1
gene id: 106582:dpm1
uniprot id: A0A3P9D4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

106582:gja5
gene id: 106582:gja5
uniprot id: A0A3P9AXD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101471362
gene id: 106582:LOC101471362
uniprot id: A0A3P9CWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:adamts18
gene id: 106582:adamts18
uniprot id: A0A3P9B5W3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:rragc
gene id: 106582:rragc
uniprot id: A0A3P9BMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

106582:LOC101476219
gene id: 106582:LOC101476219
uniprot id: A0A3P9C6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:gnpat
gene id: 106582:gnpat
uniprot id: A0A3P9BCE6
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

106582:cenpj
gene id: 106582:cenpj
uniprot id: A0A3P9CV43
names: Similarity
messages: Belongs to the TCP10 family.

106582:lg10h11orf54
gene id: 106582:lg10h11orf54
uniprot id: A0A3P9C8C6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

106582:LOC101471386
gene id: 106582:LOC101471386
uniprot id: A0A3P9CVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

106582:chmp2a
gene id: 106582:chmp2a
uniprot id: A0A3P9BM94
names: Similarity
messages: Belongs to the SNF7 family.

106582:rhbdd1
gene id: 106582:rhbdd1
uniprot id: A0A3P9DDI8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476861
gene id: 106582:LOC101476861
uniprot id: A0A3P9CK29
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

106582:LOC101466690
gene id: 106582:LOC101466690
uniprot id: A0A3P9BEF2
names: Similarity
messages: Belongs to the uridine kinase family.

106582:nol12
gene id: 106582:nol12
uniprot id: A0A3P9BAI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

106582:magi2
gene id: 106582:magi2
uniprot id: A0A3P9B110
names: Subcellular Location Annotation
messages: Membrane

106582:atg4b
gene id: 106582:atg4b
uniprot id: A0A3P9BRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

106582:ndufa10
gene id: 106582:ndufa10
uniprot id: A0A3P9CPY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

106582:LOC101466778
gene id: 106582:LOC101466778
uniprot id: A0A3P9CI41
names: Similarity
messages: Belongs to the TGF-beta family.

106582:fam57a
gene id: 106582:fam57a
uniprot id: A0A3P9B736
names: Subcellular Location Annotation
messages: Membrane

106582:acadl
gene id: 106582:acadl
uniprot id: A0A3P9CC95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

106582:LOC101485524
gene id: 106582:LOC101485524
uniprot id: A0A3P9C377
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101467736
gene id: 106582:LOC101467736
uniprot id: A0A3P9BT38
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:LOC101466508
gene id: 106582:LOC101466508
uniprot id: A0A3P9D1F2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:kitlg
gene id: 106582:kitlg
uniprot id: A0A3P9C5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

106582:LOC101470280
gene id: 106582:LOC101470280
uniprot id: A0A3P9BPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

106582:LOC101482955
gene id: 106582:LOC101482955
uniprot id: A0A3P9DHH1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

106582:appl2
gene id: 106582:appl2
uniprot id: A0A3P9BQD3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

106582:LOC101486686
gene id: 106582:LOC101486686
uniprot id: A0A3P9D7I4
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

106582:cse1l
gene id: 106582:cse1l
uniprot id: A0A3P9BWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

106582:pusl1
gene id: 106582:pusl1
uniprot id: A0A3P9DPV8
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

106582:mrpl34
gene id: 106582:mrpl34
uniprot id: A0A3P9B660
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

106582:LOC101468113
gene id: 106582:LOC101468113
uniprot id: A0A3P9CGM8
uniprot id: A0A3P9CGP5
uniprot id: A0A3P9CHL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

106582:ubald1
gene id: 106582:ubald1
uniprot id: A0A3P9BIK0
names: Similarity
messages: Belongs to the UBALD family.

106582:cmtm8
gene id: 106582:cmtm8
uniprot id: A0A3P9AZ11
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101468020
gene id: 106582:LOC101468020
uniprot id: A0A3P9BRH7
uniprot id: A0A3P9BRJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:supt4h1
gene id: 106582:supt4h1
uniprot id: A0A3P9DCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

106582:LOC101468785
gene id: 106582:LOC101468785
uniprot id: A0A3P9CFB4
uniprot id: A0A3P9CG27
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:LOC101466601
gene id: 106582:LOC101466601
uniprot id: A0A3P9CLS6
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

106582:fggy
gene id: 106582:fggy
uniprot id: A0A3P9BQD5
names: Similarity
messages: Belongs to the FGGY kinase family.

106582:LOC101474893
gene id: 106582:LOC101474893
uniprot id: A0A3P9B9J2
names: Subcellular Location Annotation
messages: Nucleus

106582:creld2
gene id: 106582:creld2
uniprot id: A0A3P9CFF1
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:plk1
gene id: 106582:plk1
uniprot id: A0A3P9C789
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

106582:nosip
gene id: 106582:nosip
uniprot id: A0A3P9AX89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

106582:alpl
gene id: 106582:alpl
uniprot id: A0A3P9AV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

106582:ndufa12
gene id: 106582:ndufa12
uniprot id: A0A3P9ATZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

106582:LOC101486912
gene id: 106582:LOC101486912
uniprot id: A0A3P9ARW4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:rpl28
gene id: 106582:rpl28
uniprot id: A0A3P9AZ48
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

106582:srd5a1
gene id: 106582:srd5a1
uniprot id: A0A3P9AR50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

106582:LOC101476932
gene id: 106582:LOC101476932
uniprot id: A0A3P9CI63
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

106582:kcnj3
gene id: 106582:kcnj3
uniprot id: A0A3P9BLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

106582:tmem98
gene id: 106582:tmem98
uniprot id: A0A3P9D852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

106582:unc119
gene id: 106582:unc119
uniprot id: A0A3P9CCV1
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

106582:LOC101484905
gene id: 106582:LOC101484905
uniprot id: A0A3P9CLZ5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

106582:LOC101477475
gene id: 106582:LOC101477475
uniprot id: A0A3P9CXR2
names: Similarity
messages: Belongs to the RimK family.

106582:LOC101484935
gene id: 106582:LOC101484935
uniprot id: A0A3P9DC67
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

106582:tmem161b
gene id: 106582:tmem161b
uniprot id: A0A3P9CBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

106582:LOC101485776
gene id: 106582:LOC101485776
uniprot id: A0A3P9C281
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:LOC101485312
gene id: 106582:LOC101485312
uniprot id: A0A3P9CKF0
names: Similarity
messages: Belongs to the peptidase C2 family.

106582:LOC101477485
gene id: 106582:LOC101477485
uniprot id: A0A3P9BEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

106582:gabrd
gene id: 106582:gabrd
uniprot id: A0A3P9D289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101473183
gene id: 106582:LOC101473183
uniprot id: A0A3P9BUJ7
names: Similarity
messages: Belongs to the GORASP family.

106582:cldn20
gene id: 106582:cldn20
uniprot id: A0A3P9BC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:eif3g
gene id: 106582:eif3g
uniprot id: A0A3P9CU16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

106582:LOC101467951
gene id: 106582:LOC101467951
uniprot id: A0A3P9CHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

106582:txlnb
gene id: 106582:txlnb
uniprot id: A0A3P9C938
names: Similarity
messages: Belongs to the taxilin family.

106582:LOC101477977
gene id: 106582:LOC101477977
uniprot id: A0A3P9CE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

106582:mdk
gene id: 106582:mdk
uniprot id: A0A3P9B0E8
names: Similarity
messages: Belongs to the pleiotrophin family.

106582:LOC101473352
gene id: 106582:LOC101473352
uniprot id: A0A3P9CFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

106582:mcm7
gene id: 106582:mcm7
uniprot id: A0A3P9BR22
uniprot id: A0A3P9BRX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

106582:gpat4
gene id: 106582:gpat4
uniprot id: A0A3P9BZ81
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:LOC101476170
gene id: 106582:LOC101476170
uniprot id: A0A3P9BRI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101467405
gene id: 106582:LOC101467405
uniprot id: A0A3P9DMN1
names: Subcellular Location Annotation
messages: Membrane

106582:papolg
gene id: 106582:papolg
uniprot id: A0A3P9CQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

106582:mfsd9
gene id: 106582:mfsd9
uniprot id: A0A3P9D4X5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101465094
gene id: 106582:LOC101465094
uniprot id: A0A3P9DDV3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101464050
gene id: 106582:LOC101464050
uniprot id: A0A3P9C3Y8
names: Subcellular Location Annotation
messages: Nucleus

106582:ift20
gene id: 106582:ift20
uniprot id: A0A3P9CVF0
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

106582:ciapin1
gene id: 106582:ciapin1
uniprot id: A0A3P9CE05
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

106582:nectin1
gene id: 106582:nectin1
uniprot id: A0A3P9DDW0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101467207
gene id: 106582:LOC101467207
uniprot id: A0A3P9B160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

106582:igf1r
gene id: 106582:igf1r
uniprot id: A0A3P9D2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:midn
gene id: 106582:midn
uniprot id: A0A3P9BUE8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478403
gene id: 106582:LOC101478403
uniprot id: A0A3P9ASW9
uniprot id: A0A3P9AT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:lrrfip2
gene id: 106582:lrrfip2
uniprot id: A0A3P9BX62
uniprot id: A0A3P9BY66
names: Similarity
messages: Belongs to the LRRFIP family.

106582:gad2
gene id: 106582:gad2
uniprot id: A0A3P9CTA7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

106582:LOC101485332
gene id: 106582:LOC101485332
uniprot id: A0A3P9BZ11
names: Subcellular Location Annotation
messages: cytoskeleton

106582:smpd2
gene id: 106582:smpd2
uniprot id: A0A3P9B1M5
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

106582:LOC101481048
gene id: 106582:LOC101481048
uniprot id: A0A3P9CSF6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:usp3
gene id: 106582:usp3
uniprot id: A0A3P9D778
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:tm2d2
gene id: 106582:tm2d2
uniprot id: A0A3P9B3E4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479275
gene id: 106582:LOC101479275
uniprot id: A0A3P9D2V5
names: Similarity
messages: Belongs to the cornifelin family.

106582:kcnk2
gene id: 106582:kcnk2
uniprot id: A0A3P9CJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:LOC101471779
gene id: 106582:LOC101471779
uniprot id: A0A3P9B6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

106582:LOC101465776
gene id: 106582:LOC101465776
uniprot id: A0A3P9C689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:aip
gene id: 106582:aip
uniprot id: A0A3P9DC26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

106582:pdrg1
gene id: 106582:pdrg1
uniprot id: A0A3P9BF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

106582:mgmt
gene id: 106582:mgmt
uniprot id: A0A3P9DR30
names: Similarity
messages: Belongs to the MGMT family.

106582:LOC101483423
gene id: 106582:LOC101483423
uniprot id: A0A3P9CBV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

106582:LOC101481778
gene id: 106582:LOC101481778
uniprot id: A0A3P9BFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101479114
gene id: 106582:LOC101479114
uniprot id: A0A3P9CJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

106582:slc25a16
gene id: 106582:slc25a16
uniprot id: A0A3P9DRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101469064
gene id: 106582:LOC101469064
uniprot id: A0A3P9DNN6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

106582:zranb1
gene id: 106582:zranb1
uniprot id: A0A3P9AWK6
names: Similarity
messages: Belongs to the peptidase C64 family.

106582:LOC101474509
gene id: 106582:LOC101474509
uniprot id: A0A3P9C765
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

106582:LOC101468139
gene id: 106582:LOC101468139
uniprot id: A0A3P9DPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

106582:acad8
gene id: 106582:acad8
uniprot id: A0A3P9B9U5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106582:APK84 gp11
gene id: 106582:APK84_gp11
uniprot id: A0A0K2CIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101469149
gene id: 106582:LOC101469149
uniprot id: A0A3P9DNN1
uniprot id: A0A3P9DP93
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

106582:prps2
gene id: 106582:prps2
uniprot id: A0A3P9D2K1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

106582:LOC101483136
gene id: 106582:LOC101483136
uniprot id: A0A3P9CHM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:grk6
gene id: 106582:grk6
uniprot id: A0A3P9C1N0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

106582:brms1l
gene id: 106582:brms1l
uniprot id: A0A3P9BL78
names: Subcellular Location Annotation
messages: Nucleus

106582:zbed4
gene id: 106582:zbed4
uniprot id: A0A3P9CED9
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101475650
gene id: 106582:LOC101475650
uniprot id: A0A3P9CWG4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101473294
gene id: 106582:LOC101473294
uniprot id: A0A3P9BME5
names: Similarity
messages: Belongs to the syntaxin family.

106582:rnf40
gene id: 106582:rnf40
uniprot id: A0A3P9BYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

106582:LOC101472733
gene id: 106582:LOC101472733
uniprot id: A0A3P9CR84
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

106582:alkal2
gene id: 106582:alkal2
uniprot id: A0A3P9CKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

106582:aldh8a1
gene id: 106582:aldh8a1
uniprot id: A0A3P9CF60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:rps6
gene id: 106582:rps6
uniprot id: A0A3P9D7M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

106582:LOC101472097
gene id: 106582:LOC101472097
uniprot id: A0A3P9BTT8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

106582:LOC101470307
gene id: 106582:LOC101470307
uniprot id: A0A3P9BPE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin E subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:LOC101474915
gene id: 106582:LOC101474915
uniprot id: A0A3P9BUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101473446
gene id: 106582:LOC101473446
uniprot id: A0A3P9BHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101474574
gene id: 106582:LOC101474574
uniprot id: A0A3P9B7F6
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:snap25
gene id: 106582:snap25
uniprot id: A0A3P9B0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

106582:col4a3bp
gene id: 106582:col4a3bp
uniprot id: A0A3P9CD96
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

106582:LOC101483411
gene id: 106582:LOC101483411
uniprot id: A0A3P9B7H9
names: Similarity
messages: Belongs to the AAA ATPase family.

106582:LOC101478057
gene id: 106582:LOC101478057
uniprot id: A0A3P9AUJ8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

106582:ccm2
gene id: 106582:ccm2
uniprot id: A0A3P9CH28
uniprot id: A0A3P9CHH1
names: Similarity
messages: Belongs to the CCM2 family.

106582:myo1d
gene id: 106582:myo1d
uniprot id: A0A3P9BKW6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:LOC101469154
gene id: 106582:LOC101469154
uniprot id: A0A3P9DPT4
names: Similarity
messages: Belongs to the intermediate filament family.

106582:mrpl17
gene id: 106582:mrpl17
uniprot id: A0A3P9B3U3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

106582:slc31a2
gene id: 106582:slc31a2
uniprot id: A0A3P9CD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

106582:LOC101467499
gene id: 106582:LOC101467499
uniprot id: A0A3P9C750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

106582:LOC101468584
gene id: 106582:LOC101468584
uniprot id: A0A3P9DQH1
names: Similarity
messages: Belongs to the pyridoxine kinase family.

106582:LOC101481996
gene id: 106582:LOC101481996
uniprot id: A0A3P9DF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

106582:tbx15
gene id: 106582:tbx15
uniprot id: A0A3P9CTY2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:cldn15
gene id: 106582:cldn15
uniprot id: A0A3P9D2B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:timm10
gene id: 106582:timm10
uniprot id: A0A3P9BXC3
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

106582:fabp7
gene id: 106582:fabp7
uniprot id: A0A3P9BF94
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:LOC101478577
gene id: 106582:LOC101478577
uniprot id: A0A3P9CVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

106582:LOC101486314
gene id: 106582:LOC101486314
uniprot id: A0A3P9B538
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:itgb8
gene id: 106582:itgb8
uniprot id: A0A3P9BJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

106582:tpm4
gene id: 106582:tpm4
uniprot id: A0A3P9BQT7
uniprot id: A0A3P9BQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

106582:camkk1
gene id: 106582:camkk1
uniprot id: A0A3P9DAR0
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:dcbld2
gene id: 106582:dcbld2
uniprot id: A0A3P9D432
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:sgms1
gene id: 106582:sgms1
uniprot id: A0A3P9DRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

106582:snrnp27
gene id: 106582:snrnp27
uniprot id: A0A3P9AWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

106582:LOC101470839
gene id: 106582:LOC101470839
uniprot id: A0A3P9CGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

106582:tmem244
gene id: 106582:tmem244
uniprot id: A0A3P9C566
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479464
gene id: 106582:LOC101479464
uniprot id: A0A3P9BTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:sdf4
gene id: 106582:sdf4
uniprot id: A0A3P9D9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

106582:sec22a
gene id: 106582:sec22a
uniprot id: A0A3P9CSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

106582:fus
gene id: 106582:fus
uniprot id: A0A3P9AXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

106582:rbp7
gene id: 106582:rbp7
uniprot id: A0A3P9C6N7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:usp45
gene id: 106582:usp45
uniprot id: A0A3P9C114
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:neu3
gene id: 106582:neu3
uniprot id: A0A3P9CLH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

106582:cpeb3
gene id: 106582:cpeb3
uniprot id: A0A3P9C1U3
names: Similarity
messages: Belongs to the RRM CPEB family.

106582:LOC101481852
gene id: 106582:LOC101481852
uniprot id: A0A3P9BKS4
names: Subcellular Location Annotation
messages: Nucleus

106582:ppp1r1a
gene id: 106582:ppp1r1a
uniprot id: A0A3P9BEU5
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

106582:supt3h
gene id: 106582:supt3h
uniprot id: A0A3P9DPA9
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101487167
gene id: 106582:LOC101487167
uniprot id: A0A3P9CUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:klhl36
gene id: 106582:klhl36
uniprot id: A0A3P9AR67
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

106582:tmem199
gene id: 106582:tmem199
uniprot id: A0A3P9B6P3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101487660
gene id: 106582:LOC101487660
uniprot id: A0A3P9BWD3
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

106582:LOC101478411
gene id: 106582:LOC101478411
uniprot id: A0A3P9D8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

106582:LOC101467983
gene id: 106582:LOC101467983
uniprot id: A0A3P9CKP9
uniprot id: A0A3P9CLD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

106582:arl14
gene id: 106582:arl14
uniprot id: A0A3P9ARY7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:LOC101477083
gene id: 106582:LOC101477083
uniprot id: A0A3P9B090
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484787
gene id: 106582:LOC101484787
uniprot id: A0A3P9D662
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:LOC101473729
gene id: 106582:LOC101473729
uniprot id: A0A3P9C6H9
uniprot id: A0A3P9C7L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101467637
gene id: 106582:LOC101467637
uniprot id: A0A3P9C0G0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:LOC101478215
gene id: 106582:LOC101478215
uniprot id: A0A3P9D6F0
names: Subcellular Location Annotation
messages: Membrane

106582:tmem184a
gene id: 106582:tmem184a
uniprot id: A0A3P9D810
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101477407
gene id: 106582:LOC101477407
uniprot id: A0A3P9BP98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101467513
gene id: 106582:LOC101467513
uniprot id: A0A3P9BZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

106582:sms
gene id: 106582:sms
uniprot id: A0A3P9CR12
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

106582:igf1
gene id: 106582:igf1
uniprot id: A0A3P9AVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

106582:cluap1
gene id: 106582:cluap1
uniprot id: A0A3P9CM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

106582:alx1
gene id: 106582:alx1
uniprot id: A0A3P9C503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

106582:LOC101478600
gene id: 106582:LOC101478600
uniprot id: A0A3P9D8R2
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

106582:LOC101487838
gene id: 106582:LOC101487838
uniprot id: A0A3P9D655
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

106582:clptm1l
gene id: 106582:clptm1l
uniprot id: A0A3P9DNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

106582:fam168a
gene id: 106582:fam168a
uniprot id: A0A3P9C9A7
names: Similarity
messages: Belongs to the FAM168 family.

106582:pdia6
gene id: 106582:pdia6
uniprot id: A0A3P9CQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

106582:LOC101482258
gene id: 106582:LOC101482258
uniprot id: A0A3P9CLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:LOC101472365
gene id: 106582:LOC101472365
uniprot id: A0A3P9B995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

106582:ddb1
gene id: 106582:ddb1
uniprot id: A0A3P9C8N8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101471718
gene id: 106582:LOC101471718
uniprot id: A0A3P9CQM1
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

106582:LOC101482727
gene id: 106582:LOC101482727
uniprot id: A0A3P9BGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

106582:tmem33
gene id: 106582:tmem33
uniprot id: A0A3P9B0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

106582:amd1
gene id: 106582:amd1
uniprot id: A0A3P9CEY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

106582:LOC101486256
gene id: 106582:LOC101486256
uniprot id: A0A3P9ATJ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101470882
gene id: 106582:LOC101470882
uniprot id: A0A3P9CXV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101482751
gene id: 106582:LOC101482751
uniprot id: A0A3P9C9M8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

106582:psap
gene id: 106582:psap
uniprot id: A0A3P9BME6
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

106582:edc4
gene id: 106582:edc4
uniprot id: A0A3P9BUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

106582:LOC101478770
gene id: 106582:LOC101478770
uniprot id: A0A3P9CTC1
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

106582:LOC101475228
gene id: 106582:LOC101475228
uniprot id: A0A3P9BN70
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

106582:slc25a32
gene id: 106582:slc25a32
uniprot id: A0A3P9C212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:pde6d
gene id: 106582:pde6d
uniprot id: A0A3P9CPJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

106582:pllp
gene id: 106582:pllp
uniprot id: A0A3P9CGG6
names: Subcellular Location Annotation
messages: Membrane

106582:slc35b3
gene id: 106582:slc35b3
uniprot id: A0A3P9CLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

106582:LOC101480050
gene id: 106582:LOC101480050
uniprot id: A0A3P9B5J4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101475004
gene id: 106582:LOC101475004
uniprot id: A0A3P9AZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

106582:bambi
gene id: 106582:bambi
uniprot id: A0A3P9CIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

106582:LOC101484164
gene id: 106582:LOC101484164
uniprot id: A0A3P9BZM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

106582:slc25a34
gene id: 106582:slc25a34
uniprot id: A0A3P9C079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:dhdds
gene id: 106582:dhdds
uniprot id: A0A3P9BL94
names: Similarity
messages: Belongs to the UPP synthase family.

106582:vill
gene id: 106582:vill
uniprot id: A0A3P9CVK6
uniprot id: A0A3P9CWP9
names: Similarity
messages: Belongs to the villin/gelsolin family.

106582:trpc1
gene id: 106582:trpc1
uniprot id: A0A3P9D4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

106582:LOC101463843
gene id: 106582:LOC101463843
uniprot id: A0A3P9BUH4
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101468145
gene id: 106582:LOC101468145
uniprot id: A0A2Z5VHB0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101477005
gene id: 106582:LOC101477005
uniprot id: A0A3P9B0M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:LOC101486855
gene id: 106582:LOC101486855
uniprot id: A0A3P9DE94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

106582:LOC101479175
gene id: 106582:LOC101479175
uniprot id: A0A3P9DBN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101472102
gene id: 106582:LOC101472102
uniprot id: A0A3P9BRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

106582:LOC101471971
gene id: 106582:LOC101471971
uniprot id: A0A3P9BVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

106582:phyhipl
gene id: 106582:phyhipl
uniprot id: A0A3P9DRQ0
names: Similarity
messages: Belongs to the PHYHIP family.

106582:runx2
gene id: 106582:runx2
uniprot id: A0A3P9BVI4
uniprot id: A0A3P9BVL0
names: Subcellular Location Annotation
messages: Nucleus

106582:tmem186
gene id: 106582:tmem186
uniprot id: A0A3P9B4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

106582:amh
gene id: 106582:amh
uniprot id: A0A3P9BEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

106582:LOC101475816
gene id: 106582:LOC101475816
uniprot id: A0A3P9CM34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

106582:LOC101481643
gene id: 106582:LOC101481643
uniprot id: A0A3P9CA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

106582:LOC101469306
gene id: 106582:LOC101469306
uniprot id: A0A3P9DGB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

106582:sesn1
gene id: 106582:sesn1
uniprot id: A0A3P9CP86
uniprot id: A0A3P9CQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

106582:LOC101487122
gene id: 106582:LOC101487122
uniprot id: A0A3P9B844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

106582:LOC101466104
gene id: 106582:LOC101466104
uniprot id: A0A3P9DPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

106582:prkab1
gene id: 106582:prkab1
uniprot id: A0A3P9CG66
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

106582:LOC101469733
gene id: 106582:LOC101469733
uniprot id: A0A3P9BWS5
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:LOC101481678
gene id: 106582:LOC101481678
uniprot id: A0A3P9DGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

106582:LOC101476722
gene id: 106582:LOC101476722
uniprot id: A0A3P9DAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:LOC101464593
gene id: 106582:LOC101464593
uniprot id: A0A3P9BN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101478236
gene id: 106582:LOC101478236
uniprot id: A0A3P9B1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:ntmt1
gene id: 106582:ntmt1
uniprot id: A0A3P9AU29
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

106582:sema6b
gene id: 106582:sema6b
uniprot id: A0A3P9BD79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101475282
gene id: 106582:LOC101475282
uniprot id: A0A3P9ARS8
uniprot id: A0A3P9ARV0
names: Similarity
messages: Belongs to the TOM1 family.

106582:LOC101475151
gene id: 106582:LOC101475151
uniprot id: A0A3P9D560
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

106582:rpain
gene id: 106582:rpain
uniprot id: A0A3P9CS61
names: Subcellular Location Annotation
messages: Nucleus

106582:cep170b
gene id: 106582:cep170b
uniprot id: A0A3P9DPL2
names: Similarity
messages: Belongs to the CEP170 family.

106582:tmed2
gene id: 106582:tmed2
uniprot id: A0A3P9BLE6
uniprot id: A0A3P9BLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

106582:lsm1
gene id: 106582:lsm1
uniprot id: A0A3P9BVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

106582:pif1
gene id: 106582:pif1
uniprot id: A0A3P9B6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

106582:LOC101472794
gene id: 106582:LOC101472794
uniprot id: A0A3P9DL68
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:smim15
gene id: 106582:smim15
uniprot id: A0A3P9BDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

106582:csnk1e
gene id: 106582:csnk1e
uniprot id: A0A3P9BCK6
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:adra1d
gene id: 106582:adra1d
uniprot id: A0A3P9DC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

106582:LOC101463858
gene id: 106582:LOC101463858
uniprot id: A0A3P9CB71
names: Similarity
messages: Belongs to the GADD45 family.

106582:nsmce2
gene id: 106582:nsmce2
uniprot id: A0A3P9BCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

106582:tmem147
gene id: 106582:tmem147
uniprot id: A0A3P9BG87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:lg16h2orf40
gene id: 106582:lg16h2orf40
uniprot id: A0A3P9D5P6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

106582:tut4
gene id: 106582:tut4
uniprot id: A0A3P9CL03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

106582:LOC101486059
gene id: 106582:LOC101486059
uniprot id: A0A3P9B5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:LOC101467323
gene id: 106582:LOC101467323
uniprot id: A0A3P9ATT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:LOC106676834
gene id: 106582:LOC106676834
uniprot id: A0A3P9BVL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:LOC101472004
gene id: 106582:LOC101472004
uniprot id: A0A3P9AY46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

106582:atxn10
gene id: 106582:atxn10
uniprot id: A0A3P9C2B0
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

106582:efna5
gene id: 106582:efna5
uniprot id: A0A3P9BHE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101483772
gene id: 106582:LOC101483772
uniprot id: A0A3P9BDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

106582:taf13
gene id: 106582:taf13
uniprot id: A0A3P9D6B6
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472155
gene id: 106582:LOC101472155
uniprot id: A0A3P9D1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

106582:LOC101464862
gene id: 106582:LOC101464862
uniprot id: A0A3P9BGR6
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

106582:LOC101465414
gene id: 106582:LOC101465414
uniprot id: A0A3P9C324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

106582:LOC101466273
gene id: 106582:LOC101466273
uniprot id: A0A3P9C2S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

106582:LOC101471712
gene id: 106582:LOC101471712
uniprot id: A0A3P9B4U0
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:pfn2
gene id: 106582:pfn2
uniprot id: A0A3P9CP41
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

106582:LOC101476272
gene id: 106582:LOC101476272
uniprot id: A0A3P9B1Q0
names: Subcellular Location Annotation
messages: Nucleus

106582:atg13
gene id: 106582:atg13
uniprot id: A0A3P9CMW3
uniprot id: A0A3P9CN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

106582:LOC101474024
gene id: 106582:LOC101474024
uniprot id: A0A3P9C1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101466784
gene id: 106582:LOC101466784
uniprot id: A0A3P9DFA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:kars
gene id: 106582:kars
uniprot id: A0A3P9CAN6
uniprot id: A0A3P9CBA5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

106582:LOC101481167
gene id: 106582:LOC101481167
uniprot id: A0A3P9B1N5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:phactr3
gene id: 106582:phactr3
uniprot id: A0A3P9BL15
uniprot id: A0A3P9BL16
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

106582:LOC101466308
gene id: 106582:LOC101466308
uniprot id: A0A3P9C544
names: Similarity
messages: Belongs to the CNKSR family.

106582:pparg
gene id: 106582:pparg
uniprot id: A0A3P9C894
uniprot id: A0A3P9C899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:camk1d
gene id: 106582:camk1d
uniprot id: A0A3P9CDM1
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:dusp6
gene id: 106582:dusp6
uniprot id: A0A3P9C638
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

106582:tp53inp1
gene id: 106582:tp53inp1
uniprot id: A0A3P9BPG7
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

106582:tmem269
gene id: 106582:tmem269
uniprot id: A0A3P9D6A8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

106582:LOC101477689
gene id: 106582:LOC101477689
uniprot id: A0A3P9CSQ8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486388
gene id: 106582:LOC101486388
uniprot id: A0A3P9D4T8
names: Subcellular Location Annotation
messages: Nucleus

106582:fam118b
gene id: 106582:fam118b
uniprot id: A0A3P9C6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

106582:LOC101478841
gene id: 106582:LOC101478841
uniprot id: A0A3P9CSB7
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

106582:LOC101488040
gene id: 106582:LOC101488040
uniprot id: A0A3P9BI44
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106582:LOC101470449
gene id: 106582:LOC101470449
uniprot id: A0A3P9BX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101484769
gene id: 106582:LOC101484769
uniprot id: A0A3P9BUD1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

106582:LOC101486461
gene id: 106582:LOC101486461
uniprot id: A0A3P9B432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

106582:LOC101468387
gene id: 106582:LOC101468387
uniprot id: A0A3P9BWL8
uniprot id: A0A3P9BWN9
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

106582:rps18
gene id: 106582:rps18
uniprot id: A0A3P9DPF0
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

106582:LOC101474579
gene id: 106582:LOC101474579
uniprot id: A0A3P9D5Y9
names: Similarity
messages: Belongs to the globin family.

106582:nop16
gene id: 106582:nop16
uniprot id: A0A3P9C1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

106582:LOC101472126
gene id: 106582:LOC101472126
uniprot id: A0A3P9C0M9
names: Similarity
messages: Belongs to the cornifelin family.

106582:LOC101483318
gene id: 106582:LOC101483318
uniprot id: A0A3P9BG49
names: Similarity
messages: Belongs to the SNF7 family.

106582:LOC101472146
gene id: 106582:LOC101472146
uniprot id: A0A3P9DF23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

106582:LOC101469554
gene id: 106582:LOC101469554
uniprot id: A0A3P9D561
uniprot id: A0A3P9D5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

106582:LOC101465436
gene id: 106582:LOC101465436
uniprot id: A0A3P9AX87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

106582:extl3
gene id: 106582:extl3
uniprot id: A0A3P9AYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

106582:LOC101465110
gene id: 106582:LOC101465110
uniprot id: A0A3P9BXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

106582:ube2g2
gene id: 106582:ube2g2
uniprot id: A0A3P9BCW6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:pih1d2
gene id: 106582:pih1d2
uniprot id: A0A3P9BI23
names: Similarity
messages: Belongs to the PIH1 family.

106582:LOC101481224
gene id: 106582:LOC101481224
uniprot id: A0A3P9DAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

106582:LOC101471880
gene id: 106582:LOC101471880
uniprot id: A0A3P9B2K6
names: Similarity
messages: Belongs to the myozenin family.

106582:sox21
gene id: 106582:sox21
uniprot id: A0A3P9B1Y5
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101475878
gene id: 106582:LOC101475878
uniprot id: A0A3P9CP47
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101481391
gene id: 106582:LOC101481391
uniprot id: A0A3P9CI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101463803
gene id: 106582:LOC101463803
uniprot id: A0A3P9DAX1
uniprot id: A0A3P9DBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

106582:sult4a1
gene id: 106582:sult4a1
uniprot id: A0A3P9BKM1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:adgrb3
gene id: 106582:adgrb3
uniprot id: A0A3P9BBJ7
names: Subcellular Location Annotation
messages: Membrane

106582:lyrm1
gene id: 106582:lyrm1
uniprot id: A0A3P9BXV1
names: Similarity
messages: Belongs to the complex I LYR family.

106582:tm9sf2
gene id: 106582:tm9sf2
uniprot id: A0A3P9BES4
uniprot id: A0A3P9BES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

106582:LOC101468558
gene id: 106582:LOC101468558
uniprot id: A0A3P9B2W9
names: Similarity
messages: Belongs to the NGF-beta family.

106582:LOC101466937
gene id: 106582:LOC101466937
uniprot id: A0A3P9BCN2
names: Subcellular Location Annotation
messages: Nucleus

106582:ogdhl
gene id: 106582:ogdhl
uniprot id: A0A3P9DQP5
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

106582:plaa
gene id: 106582:plaa
uniprot id: A0A3P9AZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

106582:LOC101485131
gene id: 106582:LOC101485131
uniprot id: A0A3P9BF28
names: Similarity
messages: Belongs to the isthmin family.

106582:LOC101485509
gene id: 106582:LOC101485509
uniprot id: A0A3P9DCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Secreted

106582:LOC101465784
gene id: 106582:LOC101465784
uniprot id: A0A3P9CW05
names: Similarity
messages: Belongs to the HMBS family.

106582:dmgdh
gene id: 106582:dmgdh
uniprot id: A0A3P9BDY8
uniprot id: A0A3P9BE02
names: Similarity
messages: Belongs to the GcvT family.

106582:glra2
gene id: 106582:glra2
uniprot id: A0A3P9AZK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

106582:LOC101468916
gene id: 106582:LOC101468916
uniprot id: A0A3P9CD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

106582:ufd1
gene id: 106582:ufd1
uniprot id: A0A3P9BT10
names: Similarity
messages: Belongs to the UFD1 family.

106582:LOC101463784
gene id: 106582:LOC101463784
uniprot id: A0A3P9CE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:gng5
gene id: 106582:gng5
uniprot id: A0A3P9AS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:emp1
gene id: 106582:emp1
uniprot id: A0A3P9B9M4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:bgn
gene id: 106582:bgn
uniprot id: A0A3P9DPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

106582:fam76b
gene id: 106582:fam76b
uniprot id: A0A3P9CG37
names: Similarity
messages: Belongs to the FAM76 family.

106582:LOC101477899
gene id: 106582:LOC101477899
uniprot id: A0A3P9AV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:LOC101481080
gene id: 106582:LOC101481080
uniprot id: A0A3P9C559
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

106582:cnot6l
gene id: 106582:cnot6l
uniprot id: A0A3P9CZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

106582:hmx2
gene id: 106582:hmx2
uniprot id: A0A3P9DRG2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484364
gene id: 106582:LOC101484364
uniprot id: A0A3P9CII6
names: Subcellular Location Annotation
messages: Membrane

106582:epha10
gene id: 106582:epha10
uniprot id: A0A3P9DKI1
names: Subcellular Location Annotation
messages: Cell membrane

106582:LOC101478731
gene id: 106582:LOC101478731
uniprot id: A0A3P9BY86
names: Similarity
messages: Belongs to the pellino family.

106582:LOC101466039
gene id: 106582:LOC101466039
uniprot id: A0A3P9BL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

106582:LOC101474604
gene id: 106582:LOC101474604
uniprot id: A0A3P9BKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

106582:ncapd2
gene id: 106582:ncapd2
uniprot id: A0A3P9CN87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

106582:allc
gene id: 106582:allc
uniprot id: A0A3P9CBE1
names: Similarity
messages: Belongs to the allantoicase family.

106582:LOC101464071
gene id: 106582:LOC101464071
uniprot id: A0A3P9C8M8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101474761
gene id: 106582:LOC101474761
uniprot id: A0A3P9B721
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

106582:emc3
gene id: 106582:emc3
uniprot id: A0A3P9BTU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

106582:LOC101487689
gene id: 106582:LOC101487689
uniprot id: A0A3P9BKP7
names: Similarity
messages: Belongs to the cytidylyltransferase family.

106582:kdelr3
gene id: 106582:kdelr3
uniprot id: A0A3P9BB13
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:gatm
gene id: 106582:gatm
uniprot id: A0A3P9BG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

106582:uncx
gene id: 106582:uncx
uniprot id: A0A3P9D6A2
names: Subcellular Location Annotation
messages: Nucleus

106582:acsf3
gene id: 106582:acsf3
uniprot id: A0A3P9AYH2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

106582:usp16
gene id: 106582:usp16
uniprot id: A0A3P9DDG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Homotetramer.
messages: Nucleus
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

106582:LOC101472537
gene id: 106582:LOC101472537
uniprot id: A0A3P9DDD5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

106582:LOC101476664
gene id: 106582:LOC101476664
uniprot id: A0A3P9BQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

106582:LOC101481410
gene id: 106582:LOC101481410
uniprot id: A0A3P9B515
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

106582:LOC101479017
gene id: 106582:LOC101479017
uniprot id: A0A3P9BMY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

106582:LOC101477840
gene id: 106582:LOC101477840
uniprot id: A0A3P9C9S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:LOC101473782
gene id: 106582:LOC101473782
uniprot id: A0A3P9DLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

106582:LOC101479826
gene id: 106582:LOC101479826
uniprot id: A0A3P9BKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

106582:rab27b
gene id: 106582:rab27b
uniprot id: A0A3P9C9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

106582:LOC101477426
gene id: 106582:LOC101477426
uniprot id: A0A3P9B159
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

106582:nipal3
gene id: 106582:nipal3
uniprot id: A0A3P9B7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

106582:LOC101481403
gene id: 106582:LOC101481403
uniprot id: A0A3P9BQN7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

106582:LOC101471893
gene id: 106582:LOC101471893
uniprot id: A0A3P9D6W7
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101480242
gene id: 106582:LOC101480242
uniprot id: A0A3P9CRD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

106582:pla2g4a
gene id: 106582:pla2g4a
uniprot id: A0A3P9CR94
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

106582:vipas39
gene id: 106582:vipas39
uniprot id: A0A3P9CD19
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Vesicle

106582:LOC101466397
gene id: 106582:LOC101466397
uniprot id: A0A3P9CGM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

106582:wfikkn1
gene id: 106582:wfikkn1
uniprot id: A0A3P9BQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

106582:LOC101481924
gene id: 106582:LOC101481924
uniprot id: A0A3P9AT92
uniprot id: A0A3P9AU62
names: Similarity
messages: Belongs to the TEX28 family.

106582:LOC101472714
gene id: 106582:LOC101472714
uniprot id: A0A3P9BS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

106582:LOC101482514
gene id: 106582:LOC101482514
uniprot id: A0A3P9CXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

106582:LOC101477010
gene id: 106582:LOC101477010
uniprot id: A0A3P9DEU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

106582:LOC101483073
gene id: 106582:LOC101483073
uniprot id: A0A3P9BTU7
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

106582:hnrnpk
gene id: 106582:hnrnpk
uniprot id: A0A3P9B7S3
uniprot id: A0A3P9B7U2
names: Subcellular Location Annotation
messages: nucleoplasm

106582:LOC101484680
gene id: 106582:LOC101484680
uniprot id: A0A3P9DEP7
uniprot id: A0A3P9DG90
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

106582:sned1
gene id: 106582:sned1
uniprot id: A0A3P9BQ95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101486201
gene id: 106582:LOC101486201
uniprot id: A0A3P9DM60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

106582:LOC101463569
gene id: 106582:LOC101463569
uniprot id: A0A3P9AXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101480595
gene id: 106582:LOC101480595
uniprot id: A0A3P9DFC7
names: Subcellular Location Annotation
messages: Cytoplasm

106582:ugt8
gene id: 106582:ugt8
uniprot id: A0A3P9DAE7
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

106582:epn2
gene id: 106582:epn2
uniprot id: A0A3P9BN11
names: Similarity
messages: Belongs to the epsin family.

106582:LOC101464389
gene id: 106582:LOC101464389
uniprot id: A0A3P9DLZ0
names: Similarity
messages: Belongs to the BicD family.

106582:LOC101485158
gene id: 106582:LOC101485158
uniprot id: A0A3P9D0B2
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

106582:LOC101471298
gene id: 106582:LOC101471298
uniprot id: A0A3P9AS10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

106582:trdmt1
gene id: 106582:trdmt1
uniprot id: A0A3P9CHZ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

106582:LOC101469325
gene id: 106582:LOC101469325
uniprot id: A0A3P9CRZ0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

106582:nfix
gene id: 106582:nfix
uniprot id: A0A3P9D8G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

106582:LOC101478476
gene id: 106582:LOC101478476
uniprot id: A0A3P9CB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101464514
gene id: 106582:LOC101464514
uniprot id: A0A3P9DE19
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480130
gene id: 106582:LOC101480130
uniprot id: A0A3P9BU16
uniprot id: A0A3P9BUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Membrane

106582:rnf146
gene id: 106582:rnf146
uniprot id: A0A3P9C645
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

106582:sh3bgrl
gene id: 106582:sh3bgrl
uniprot id: A0A3P9BGC5
names: Similarity
messages: Belongs to the SH3BGR family.

106582:kif22
gene id: 106582:kif22
uniprot id: A0A3P9C8F2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:mlst8
gene id: 106582:mlst8
uniprot id: A0A3P9BKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

106582:hhat
gene id: 106582:hhat
uniprot id: A0A3P9DQE8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469037
gene id: 106582:LOC101469037
uniprot id: A0A3P9BQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

106582:cdk7
gene id: 106582:cdk7
uniprot id: A0A3P9CKS8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

106582:LOC101467443
gene id: 106582:LOC101467443
uniprot id: A0A3P9B317
uniprot id: A0A3P9B3G3
names: Similarity
messages: Belongs to the syntaxin family.

106582:LOC101485530
gene id: 106582:LOC101485530
uniprot id: A0A3P9CFH3
names: Similarity
messages: Belongs to the ependymin family.

106582:LOC101482058
gene id: 106582:LOC101482058
uniprot id: A0A3P9BLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:LOC101474998
gene id: 106582:LOC101474998
uniprot id: A0A3P9CIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:LOC101473650
gene id: 106582:LOC101473650
uniprot id: A0A3P9C2J6
uniprot id: A0A3P9C3I0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

106582:LOC101472506
gene id: 106582:LOC101472506
uniprot id: A0A3P9CDL9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

106582:LOC101479942
gene id: 106582:LOC101479942
uniprot id: A0A3P9DJ65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101484014
gene id: 106582:LOC101484014
uniprot id: A0A3P9BPD3
uniprot id: A0A3P9BPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

106582:LOC101466963
gene id: 106582:LOC101466963
uniprot id: A0A3P9CIV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:nodal
gene id: 106582:nodal
uniprot id: A0A3P9AU06
names: Similarity
messages: Belongs to the TGF-beta family.

106582:chst12
gene id: 106582:chst12
uniprot id: A0A3P9C1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101486638
gene id: 106582:LOC101486638
uniprot id: A0A3P9AS34
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:otud7b
gene id: 106582:otud7b
uniprot id: A0A3P9CJA6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101476840
gene id: 106582:LOC101476840
uniprot id: A0A3P9BCH8
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

106582:ufm1
gene id: 106582:ufm1
uniprot id: A0A3P9DE05
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

106582:tfap2b
gene id: 106582:tfap2b
uniprot id: A0A3P9B8N9
uniprot id: A0A3P9B8S5
names: Similarity
messages: Belongs to the AP-2 family.

106582:mrpl23
gene id: 106582:mrpl23
uniprot id: A0A3P9CMP6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

106582:LOC101482707
gene id: 106582:LOC101482707
uniprot id: A0A3P9BHG6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

106582:cdk2ap2
gene id: 106582:cdk2ap2
uniprot id: A0A3P9DC50
names: Similarity
messages: Belongs to the CDK2AP family.

106582:pitx1
gene id: 106582:pitx1
uniprot id: A0A3P9BQS9
uniprot id: A0A3P9BQU0
uniprot id: A0A3P9BRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

106582:LOC101468031
gene id: 106582:LOC101468031
uniprot id: A0A3P9B4M8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

106582:ldlrad4
gene id: 106582:ldlrad4
uniprot id: A0A3P9DHR6
uniprot id: A0A3P9DHV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101471749
gene id: 106582:LOC101471749
uniprot id: A0A3P9CRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

106582:arsa
gene id: 106582:arsa
uniprot id: A0A3P9CWT0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

106582:LOC101477326
gene id: 106582:LOC101477326
uniprot id: A0A3P9C113
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

106582:slc25a21
gene id: 106582:slc25a21
uniprot id: A0A3P9CCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:sucla2
gene id: 106582:sucla2
uniprot id: A0A3P9CY88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

106582:polr2h
gene id: 106582:polr2h
uniprot id: A0A3P9CM21
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

106582:tcf7l2
gene id: 106582:tcf7l2
uniprot id: A0A3P9CGV1
uniprot id: A0A3P9CGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

106582:LOC101480911
gene id: 106582:LOC101480911
uniprot id: A0A3P9C3H3
names: Similarity
messages: Belongs to the FAM53 family.

106582:LOC101473522
gene id: 106582:LOC101473522
uniprot id: A0A3P9BYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

106582:apex1
gene id: 106582:apex1
uniprot id: A0A3P9C9Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

106582:LOC101471537
gene id: 106582:LOC101471537
uniprot id: A0A3P9D2T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

106582:ttyh2
gene id: 106582:ttyh2
uniprot id: A0A3P9B9I0
uniprot id: A0A3P9B9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

106582:LOC101468680
gene id: 106582:LOC101468680
uniprot id: A0A3P9BWY5
names: Similarity
messages: Belongs to the CRK family.

106582:LOC101467176
gene id: 106582:LOC101467176
uniprot id: A0A3P9CZZ4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

106582:nol6
gene id: 106582:nol6
uniprot id: A0A3P9C9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

106582:dhtkd1
gene id: 106582:dhtkd1
uniprot id: A0A3P9BGV7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

106582:LOC101467994
gene id: 106582:LOC101467994
uniprot id: A0A3P9AY87
names: Similarity
messages: Belongs to the synaptotagmin family.

106582:LOC101463638
gene id: 106582:LOC101463638
uniprot id: A0A3P9B9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

106582:LOC101464051
gene id: 106582:LOC101464051
uniprot id: A0A3P9B3D7
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101471220
gene id: 106582:LOC101471220
uniprot id: A0A3P9B521
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:itk
gene id: 106582:itk
uniprot id: A0A3P9BLA7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:dkk2
gene id: 106582:dkk2
uniprot id: A0A3P9CWY0
names: Similarity
messages: Belongs to the dickkopf family.

106582:LOC101473544
gene id: 106582:LOC101473544
uniprot id: A0A3P9BSZ6
names: Similarity
messages: Belongs to the intermediate filament family.

106582:LOC101481568
gene id: 106582:LOC101481568
uniprot id: A0A3P9BMX0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

106582:megf9
gene id: 106582:megf9
uniprot id: A0A3P9B626
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:irf7
gene id: 106582:irf7
uniprot id: A0A3P9CMH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC101466461
gene id: 106582:LOC101466461
uniprot id: A0A3P9D9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

106582:LOC101481649
gene id: 106582:LOC101481649
uniprot id: A0A3P9BR29
names: Similarity
messages: Belongs to the TTC39 family.

106582:LOC101471123
gene id: 106582:LOC101471123
uniprot id: A0A3P9AYU0
uniprot id: A0A3P9AYV9
uniprot id: A0A3P9AZK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

106582:LOC101464263
gene id: 106582:LOC101464263
uniprot id: A0A3P9ASS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

106582:LOC101482399
gene id: 106582:LOC101482399
uniprot id: A0A3P9C1Y9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486922
gene id: 106582:LOC101486922
uniprot id: A0A3P9C0W8
names: Similarity
messages: Belongs to the RNase T2 family.

106582:tdrd3
gene id: 106582:tdrd3
uniprot id: A0A3P9B7J9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

106582:LOC101483611
gene id: 106582:LOC101483611
uniprot id: A0A3P9CHZ0
names: Subcellular Location Annotation
messages: Membrane

106582:hyi
gene id: 106582:hyi
uniprot id: A0A3P9B396
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

106582:trnt1
gene id: 106582:trnt1
uniprot id: A0A3P9BRB0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

106582:LOC101484618
gene id: 106582:LOC101484618
uniprot id: A0A3P9ATQ5
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

106582:slc16a7
gene id: 106582:slc16a7
uniprot id: A0A3P9CPU2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

106582:tubg1
gene id: 106582:tubg1
uniprot id: A0A3P9D8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

106582:LOC101466608
gene id: 106582:LOC101466608
uniprot id: A0A3P9BBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

106582:agtrap
gene id: 106582:agtrap
uniprot id: A0A3P9AT42
names: Subcellular Location Annotation
messages: Membrane

106582:plcg1
gene id: 106582:plcg1
uniprot id: A0A3P9DLD6
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

106582:LOC101468551
gene id: 106582:LOC101468551
uniprot id: A0A3P9DFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

106582:b3gat3
gene id: 106582:b3gat3
uniprot id: A0A3P9B3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:polb
gene id: 106582:polb
uniprot id: A0A3P9BTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

106582:LOC101471463
gene id: 106582:LOC101471463
uniprot id: A0A3P9D959
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

106582:cntfr
gene id: 106582:cntfr
uniprot id: A0A3P9CIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Membrane

106582:LOC101486306
gene id: 106582:LOC101486306
uniprot id: A0A3P9BXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

106582:fdft1
gene id: 106582:fdft1
uniprot id: A0A3P9CIV9
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

106582:LOC101474518
gene id: 106582:LOC101474518
uniprot id: A0A3P9B095
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

106582:tbccd1
gene id: 106582:tbccd1
uniprot id: A0A3P9D1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

106582:LOC101475192
gene id: 106582:LOC101475192
uniprot id: A0A3P9CBZ6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:cmc2
gene id: 106582:cmc2
uniprot id: A0A3P9C287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

106582:myd88
gene id: 106582:myd88
uniprot id: A0A3P9CVB2
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

106582:LOC101486042
gene id: 106582:LOC101486042
uniprot id: A0A3P9DNL6
names: Subcellular Location Annotation
messages: Membrane

106582:bpgm
gene id: 106582:bpgm
uniprot id: A0A3P9BJQ0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

106582:arf1
gene id: 106582:arf1
uniprot id: A0A3P9DH75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

106582:LOC101472737
gene id: 106582:LOC101472737
uniprot id: A0A3P9B5L4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101467476
gene id: 106582:LOC101467476
uniprot id: A0A3P9CXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:lamp3
gene id: 106582:lamp3
uniprot id: A0A3P9CF74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

106582:slc7a11
gene id: 106582:slc7a11
uniprot id: A0A3P9CLX8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479671
gene id: 106582:LOC101479671
uniprot id: A0A3P9BZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

106582:LOC101467339
gene id: 106582:LOC101467339
uniprot id: A0A3P9C9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

106582:LOC101472204
gene id: 106582:LOC101472204
uniprot id: A0A3P9DCY7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101464986
gene id: 106582:LOC101464986
uniprot id: A0A3P9D292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

106582:mfn1
gene id: 106582:mfn1
uniprot id: A0A3P9AYT5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

106582:lg22h1orf43
gene id: 106582:lg22h1orf43
uniprot id: A0A3P9DLC6
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

106582:LOC101469257
gene id: 106582:LOC101469257
uniprot id: A0A3P9CL16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

106582:LOC101470463
gene id: 106582:LOC101470463
uniprot id: A0A3P9CKZ1
names: Similarity
messages: Belongs to the HEBP family.

106582:LOC101471215
gene id: 106582:LOC101471215
uniprot id: A0A3P9C496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:vps18
gene id: 106582:vps18
uniprot id: A0A3P9C6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

106582:LOC101486928
gene id: 106582:LOC101486928
uniprot id: A0A3P9BUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

106582:LOC101471711
gene id: 106582:LOC101471711
uniprot id: A0A3P9BVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101477540
gene id: 106582:LOC101477540
uniprot id: A0A3P9CS96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

106582:cyfip2
gene id: 106582:cyfip2
uniprot id: A0A3P9BL06
names: Similarity
messages: Belongs to the CYFIP family.

106582:polr2a
gene id: 106582:polr2a
uniprot id: A0A3P9D2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

106582:eny2
gene id: 106582:eny2
uniprot id: A0A3P9BZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

106582:gk5
gene id: 106582:gk5
uniprot id: A0A3P9BAB8
names: Similarity
messages: Belongs to the FGGY kinase family.

106582:LOC101472966
gene id: 106582:LOC101472966
uniprot id: A0A3P9BVU0
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101480226
gene id: 106582:LOC101480226
uniprot id: A0A3P9CQI7
names: Similarity
messages: Belongs to the PP2C family.

106582:rmnd1
gene id: 106582:rmnd1
uniprot id: A0A3P9C6C8
names: Similarity
messages: Belongs to the RMD1/sif2 family.

106582:LOC101466647
gene id: 106582:LOC101466647
uniprot id: A0A3P9DPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

106582:LOC101480906
gene id: 106582:LOC101480906
uniprot id: A0A3P9BCU4
uniprot id: A0A3P9BCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

106582:st7
gene id: 106582:st7
uniprot id: A0A3P9C796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

106582:rbm22
gene id: 106582:rbm22
uniprot id: A0A3P9C4V2
names: Similarity
messages: Belongs to the SLT11 family.

106582:LOC101486126
gene id: 106582:LOC101486126
uniprot id: A0A3P9D7Y5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

106582:med30
gene id: 106582:med30
uniprot id: A0A3P9DLW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

106582:LOC101469126
gene id: 106582:LOC101469126
uniprot id: A0A3P9D2L5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101465268
gene id: 106582:LOC101465268
uniprot id: A0A3P9C6M9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

106582:sepsecs
gene id: 106582:sepsecs
uniprot id: A0A3P9AXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

106582:ace
gene id: 106582:ace
uniprot id: A0A3P9BTC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

106582:LOC101478671
gene id: 106582:LOC101478671
uniprot id: A0A3P9DHX8
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

106582:LOC101470540
gene id: 106582:LOC101470540
uniprot id: A0A3P9BS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

106582:chmp7
gene id: 106582:chmp7
uniprot id: A0A3P9BKL7
names: Similarity
messages: Belongs to the SNF7 family.

106582:LOC101474556
gene id: 106582:LOC101474556
uniprot id: A0A3P9BGT5
names: Similarity
messages: Belongs to the WD repeat EBI family.

106582:meis2
gene id: 106582:meis2
uniprot id: A0A3P9B088
uniprot id: A0A3P9B0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

106582:LOC101486168
gene id: 106582:LOC101486168
uniprot id: A0A3P9BU35
names: Similarity
messages: Belongs to the SNF7 family.

106582:ano3
gene id: 106582:ano3
uniprot id: A0A3P9AZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

106582:LOC101466729
gene id: 106582:LOC101466729
uniprot id: A0A3P9CWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

106582:LOC101475894
gene id: 106582:LOC101475894
uniprot id: A0A3P9AYT7
names: Similarity
messages: Belongs to the BZW family.

106582:pcmt1
gene id: 106582:pcmt1
uniprot id: A0A3P9B9F9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106582:LOC101478744
gene id: 106582:LOC101478744
uniprot id: A0A3P9ASS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:pola2
gene id: 106582:pola2
uniprot id: A0A3P9B644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

106582:nsg1
gene id: 106582:nsg1
uniprot id: A0A3P9DP67
names: Similarity
messages: Belongs to the NSG family.

106582:LOC101474197
gene id: 106582:LOC101474197
uniprot id: A0A3P9DMF3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

106582:cwc15
gene id: 106582:cwc15
uniprot id: A0A3P9CGB9
names: Similarity
messages: Belongs to the CWC15 family.

106582:s100z
gene id: 106582:s100z
uniprot id: A0A3P9BGF8
names: Similarity
messages: Belongs to the S-100 family.

106582:LOC101471103
gene id: 106582:LOC101471103
uniprot id: A0A3P9BKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

106582:mars
gene id: 106582:mars
uniprot id: A0A3P9BHS6
uniprot id: A0A3P9BI63
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:LOC101463621
gene id: 106582:LOC101463621
uniprot id: A0A3P9CK38
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

106582:gnmt
gene id: 106582:gnmt
uniprot id: A0A3P9BGV1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

106582:LOC101478888
gene id: 106582:LOC101478888
uniprot id: A0A3P9AV90
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

106582:wnt9b
gene id: 106582:wnt9b
uniprot id: A0A3P9D6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101478185
gene id: 106582:LOC101478185
uniprot id: A0A3P9B688
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

106582:LOC101479607
gene id: 106582:LOC101479607
uniprot id: A0A3P9CNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

106582:taldo1
gene id: 106582:taldo1
uniprot id: A0A3P9C7X3
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

106582:LOC106674910
gene id: 106582:LOC106674910
uniprot id: A0A3P9AX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101476482
gene id: 106582:LOC101476482
uniprot id: A0A3P9AXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101464440
gene id: 106582:LOC101464440
uniprot id: A0A3P9AY99
names: Subcellular Location Annotation
messages: Membrane

106582:rnf20
gene id: 106582:rnf20
uniprot id: A0A3P9C6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

106582:fgf2
gene id: 106582:fgf2
uniprot id: A0A3P9B1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

106582:mrpl20
gene id: 106582:mrpl20
uniprot id: A0A3P9BZ74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

106582:dimt1
gene id: 106582:dimt1
uniprot id: A0A3P9CL52
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

106582:LOC101467446
gene id: 106582:LOC101467446
uniprot id: A0A3P9DAR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

106582:mlf2
gene id: 106582:mlf2
uniprot id: A0A3P9CN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

106582:cacybp
gene id: 106582:cacybp
uniprot id: A0A3P9DIW7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

106582:LOC101471348
gene id: 106582:LOC101471348
uniprot id: A0A3P9B3U1
names: Similarity
messages: Belongs to the TAFA family.

106582:fam192a
gene id: 106582:fam192a
uniprot id: A0A3P9BWI4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101466307
gene id: 106582:LOC101466307
uniprot id: A0A3P9BRV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101480405
gene id: 106582:LOC101480405
uniprot id: A0A3P9DA99
names: Similarity
messages: Belongs to the NATD1 family.

106582:LOC101466873
gene id: 106582:LOC101466873
uniprot id: A0A3P9BUM8
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

106582:mapre1
gene id: 106582:mapre1
uniprot id: A0A3P9DNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

106582:LOC101468693
gene id: 106582:LOC101468693
uniprot id: A0A3P9CXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

106582:LOC101478927
gene id: 106582:LOC101478927
uniprot id: A0A3P9DP63
uniprot id: A0A3P9DPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

106582:LOC101485013
gene id: 106582:LOC101485013
uniprot id: A0A3P9B9W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:LOC101466654
gene id: 106582:LOC101466654
uniprot id: A0A3P9CPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

106582:cnr1
gene id: 106582:cnr1
uniprot id: A0A3P9AYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

106582:ppil3
gene id: 106582:ppil3
uniprot id: A0A3P9CAB8
uniprot id: A0A3P9CAC3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106582:dram1
gene id: 106582:dram1
uniprot id: A0A3P9B4B0
names: Subcellular Location Annotation
messages: Membrane

106582:btg3
gene id: 106582:btg3
uniprot id: A0A3P9D9I5
names: Similarity
messages: Belongs to the BTG family.

106582:ints9
gene id: 106582:ints9
uniprot id: A0A3P9B4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

106582:LOC101480039
gene id: 106582:LOC101480039
uniprot id: A0A3P9AS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

106582:LOC101484757
gene id: 106582:LOC101484757
uniprot id: A0A3P9DKU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

106582:LOC101472424
gene id: 106582:LOC101472424
uniprot id: A0A3P9BD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

106582:LOC101469679
gene id: 106582:LOC101469679
uniprot id: A0A3P9C1Y6
names: Similarity
messages: Belongs to the Rho GDI family.

106582:LOC101483255
gene id: 106582:LOC101483255
uniprot id: A0A3P9DB76
names: Subcellular Location Annotation
messages: Membrane

106582:gng10
gene id: 106582:gng10
uniprot id: A0A3P9ARC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101487686
gene id: 106582:LOC101487686
uniprot id: A0A3P9AUN5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106582:LOC101482948
gene id: 106582:LOC101482948
uniprot id: A0A3P9ATJ1
names: Similarity
messages: Belongs to the KHDRBS family.

106582:slc33a1
gene id: 106582:slc33a1
uniprot id: A0A3P9C371
names: Subcellular Location Annotation
messages: Membrane

106582:capn7
gene id: 106582:capn7
uniprot id: A0A3P9BS77
names: Similarity
messages: Belongs to the peptidase C2 family.

106582:LOC101487226
gene id: 106582:LOC101487226
uniprot id: A0A3P9BSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

106582:abhd16a
gene id: 106582:abhd16a
uniprot id: A0A3P9CR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

106582:kpna3
gene id: 106582:kpna3
uniprot id: A0A3P9D5M9
names: Similarity
messages: Belongs to the importin alpha family.

106582:ddo
gene id: 106582:ddo
uniprot id: A0A3P9C4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

106582:dhodh
gene id: 106582:dhodh
uniprot id: A0A3P9AXS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

106582:arhgap26
gene id: 106582:arhgap26
uniprot id: A0A3P9B1L5
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

106582:LOC101476203
gene id: 106582:LOC101476203
uniprot id: A0A3P9DL70
names: Similarity
messages: Belongs to the intermediate filament family.

106582:LOC101468957
gene id: 106582:LOC101468957
uniprot id: A0A3P9C4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

106582:rbm47
gene id: 106582:rbm47
uniprot id: A0A3P9DBG1
uniprot id: A0A3P9DC41
uniprot id: A0A3P9DC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

106582:anapc15
gene id: 106582:anapc15
uniprot id: A0A3P9BJR0
names: Similarity
messages: Belongs to the APC15 family.

106582:LOC101482066
gene id: 106582:LOC101482066
uniprot id: A0A3P9C361
names: Subcellular Location Annotation
messages: extracellular matrix

106582:coro1c
gene id: 106582:coro1c
uniprot id: A0A3P9CDR2
names: Similarity
messages: Belongs to the WD repeat coronin family.

106582:chrnb1
gene id: 106582:chrnb1
uniprot id: A0A3P9BB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:sppl3
gene id: 106582:sppl3
uniprot id: A0A3P9CQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

106582:pou4f3
gene id: 106582:pou4f3
uniprot id: A0A3P9B0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:fam199x
gene id: 106582:fam199x
uniprot id: A0A3P9BBJ8
names: Similarity
messages: Belongs to the FAM199 family.

106582:p4ha1
gene id: 106582:p4ha1
uniprot id: A0A3P9DR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

106582:gtf2f1
gene id: 106582:gtf2f1
uniprot id: A0A3P9C2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

106582:LOC101471340
gene id: 106582:LOC101471340
uniprot id: A0A3P9DJX5
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

106582:metap2
gene id: 106582:metap2
uniprot id: A0A3P9BFS1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

106582:LOC101468100
gene id: 106582:LOC101468100
uniprot id: A0A3P9DA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:LOC101470007
gene id: 106582:LOC101470007
uniprot id: A0A3P9CRI5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

106582:LOC101468714
gene id: 106582:LOC101468714
uniprot id: A0A3P9CN37
names: Similarity
messages: Belongs to the PPP phosphatase family.

106582:LOC101470003
gene id: 106582:LOC101470003
uniprot id: A0A3P9BTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

106582:etfa
gene id: 106582:etfa
uniprot id: A0A3P9D7G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

106582:tsr2
gene id: 106582:tsr2
uniprot id: A0A3P9DNN2
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

106582:LOC101481087
gene id: 106582:LOC101481087
uniprot id: A0A3P9AU66
names: Similarity
messages: Belongs to the PPase family.

106582:nhsl2
gene id: 106582:nhsl2
uniprot id: A0A3P9CWT2
uniprot id: A0A3P9CXR8
names: Similarity
messages: Belongs to the NHS family.

106582:LOC101477855
gene id: 106582:LOC101477855
uniprot id: A0A3P9DQS6
uniprot id: A0A3P9DQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101471369
gene id: 106582:LOC101471369
uniprot id: A0A3P9CN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

106582:hacd1
gene id: 106582:hacd1
uniprot id: A0A3P9AVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:lrrc4b
gene id: 106582:lrrc4b
uniprot id: A0A3P9D9X4
names: Subcellular Location Annotation
messages: Membrane

106582:stra6
gene id: 106582:stra6
uniprot id: A0A3P9D808
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101470766
gene id: 106582:LOC101470766
uniprot id: A0A3P9CFZ0
names: Similarity
messages: Belongs to the CARF family.

106582:gsk3b
gene id: 106582:gsk3b
uniprot id: A0A3P9AVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

106582:LOC101464700
gene id: 106582:LOC101464700
uniprot id: A0A3P9B693
names: Subcellular Location Annotation
messages: Nucleus

106582:chrdl2
gene id: 106582:chrdl2
uniprot id: A0A3P9CKN2
names: Subcellular Location Annotation
messages: Secreted

106582:ing2
gene id: 106582:ing2
uniprot id: A0A3P9BQ32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

106582:nudc
gene id: 106582:nudc
uniprot id: A0A3P9CJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

106582:arhgef12
gene id: 106582:arhgef12
uniprot id: A0A3P9CFP3
uniprot id: A0A3P9CFY4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

106582:gabpa
gene id: 106582:gabpa
uniprot id: A0A3P9D774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101466738
gene id: 106582:LOC101466738
uniprot id: A0A3P9B8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

106582:arpc5
gene id: 106582:arpc5
uniprot id: A0A3P9CR81
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

106582:mon1a
gene id: 106582:mon1a
uniprot id: A0A3P9BVL3
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

106582:med16
gene id: 106582:med16
uniprot id: A0A3P9D091
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:galnt13
gene id: 106582:galnt13
uniprot id: A0A3P9BLT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

106582:naa30
gene id: 106582:naa30
uniprot id: A0A3P9BYD0
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

106582:LOC105941385
gene id: 106582:LOC105941385
uniprot id: A0A3P9BFK0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:pex3
gene id: 106582:pex3
uniprot id: A0A3P9C4G0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

106582:LOC101467950
gene id: 106582:LOC101467950
uniprot id: A0A3P9C105
names: Subcellular Location Annotation
messages: Membrane

106582:ppm1e
gene id: 106582:ppm1e
uniprot id: A0A3P9BT20
names: Similarity
messages: Belongs to the PP2C family.

106582:slc4a11
gene id: 106582:slc4a11
uniprot id: A0A3P9B2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

106582:xpo6
gene id: 106582:xpo6
uniprot id: A0A3P9BW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101471812
gene id: 106582:LOC101471812
uniprot id: A0A3P9C2X7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:LOC101482285
gene id: 106582:LOC101482285
uniprot id: A0A3P9CDB5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101467283
gene id: 106582:LOC101467283
uniprot id: A0A3P9BWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

106582:LOC101463771
gene id: 106582:LOC101463771
uniprot id: A0A3P9B8J1
names: Similarity
messages: Belongs to the peptidase C14A family.

106582:LOC101465362
gene id: 106582:LOC101465362
uniprot id: A0A3P9CEG5
names: Similarity
messages: Belongs to the acylphosphatase family.

106582:abr
gene id: 106582:abr
uniprot id: A0A3P9C887
uniprot id: A0A3P9C8B6
uniprot id: A0A3P9C8V7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

106582:pik3cd
gene id: 106582:pik3cd
uniprot id: A0A3P9C6Q7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

106582:tcp11
gene id: 106582:tcp11
uniprot id: A0A3P9AYQ1
names: Similarity
messages: Belongs to the TCP11 family.

106582:LOC101476434
gene id: 106582:LOC101476434
uniprot id: A0A3P9CY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

106582:LOC101467334
gene id: 106582:LOC101467334
uniprot id: A0A3P9B0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

106582:LOC101464299
gene id: 106582:LOC101464299
uniprot id: A0A3P9D003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

106582:LOC101463618
gene id: 106582:LOC101463618
uniprot id: A0A3P9CKW7
names: Subcellular Location Annotation
messages: Membrane

106582:dtx3
gene id: 106582:dtx3
uniprot id: A0A3P9AR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

106582:LOC101478677
gene id: 106582:LOC101478677
uniprot id: A0A3P9DR00
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:htr1d
gene id: 106582:htr1d
uniprot id: A0A3P9B921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:prkch
gene id: 106582:prkch
uniprot id: A0A3P9BIK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

106582:LOC101476588
gene id: 106582:LOC101476588
uniprot id: A0A3P9AZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

106582:prkar1a
gene id: 106582:prkar1a
uniprot id: A0A3P9BQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

106582:LOC101464765
gene id: 106582:LOC101464765
uniprot id: A0A3P9DMI9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

106582:LOC101476212
gene id: 106582:LOC101476212
uniprot id: A0A3P9BCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

106582:LOC101468918
gene id: 106582:LOC101468918
uniprot id: A0A3P9B3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:antxr2
gene id: 106582:antxr2
uniprot id: A0A3P9CYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

106582:prrc1
gene id: 106582:prrc1
uniprot id: A0A3P9C0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

106582:hao2
gene id: 106582:hao2
uniprot id: A0A3P9CV23
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

106582:neto2
gene id: 106582:neto2
uniprot id: A0A3P9B711
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC105941027
gene id: 106582:LOC105941027
uniprot id: A0A3P9B3Q9
names: Subcellular Location Annotation
messages: Secreted

106582:cant1
gene id: 106582:cant1
uniprot id: A0A3P9C5W2
uniprot id: A0A3P9C6B8
names: Similarity
messages: Belongs to the apyrase family.

106582:slc35b2
gene id: 106582:slc35b2
uniprot id: A0A3P9AVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

106582:LOC101466081
gene id: 106582:LOC101466081
uniprot id: A0A3P9BIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

106582:LOC101475249
gene id: 106582:LOC101475249
uniprot id: A0A3P9D5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:itm2b
gene id: 106582:itm2b
uniprot id: A0A3P9CZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

106582:LOC101472906
gene id: 106582:LOC101472906
uniprot id: A0A3P9CXE6
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

106582:LOC101481166
gene id: 106582:LOC101481166
uniprot id: A0A3P9DPA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

106582:cnrip1
gene id: 106582:cnrip1
uniprot id: A0A3P9DPI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

106582:LOC101482762
gene id: 106582:LOC101482762
uniprot id: A0A3P9B6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

106582:LOC101472203
gene id: 106582:LOC101472203
uniprot id: A0A3P9BX19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

106582:LOC101487925
gene id: 106582:LOC101487925
uniprot id: A0A3P9DMC0
names: Similarity
messages: Belongs to the actin family.

106582:nt5dc3
gene id: 106582:nt5dc3
uniprot id: A0A3P9BDR0
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

106582:LOC101477374
gene id: 106582:LOC101477374
uniprot id: A0A3P9ATB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

106582:LOC101478013
gene id: 106582:LOC101478013
uniprot id: A0A3P9CPT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101465460
gene id: 106582:LOC101465460
uniprot id: A0A3P9AWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:ing1
gene id: 106582:ing1
uniprot id: A0A3P9D5R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

106582:ahcyl1
gene id: 106582:ahcyl1
uniprot id: A0A3P9BFY2
uniprot id: A0A3P9BGE7
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

106582:mpp5
gene id: 106582:mpp5
uniprot id: A0A3P9AX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

106582:nkx6-1
gene id: 106582:nkx6-1
uniprot id: A0A3P9DAU4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484828
gene id: 106582:LOC101484828
uniprot id: A0A3P9C905
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:letmd1
gene id: 106582:letmd1
uniprot id: A0A3P9DMT2
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479670
gene id: 106582:LOC101479670
uniprot id: A0A3P9CAV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

106582:LOC101476199
gene id: 106582:LOC101476199
uniprot id: A0A3P9CK49
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101468559
gene id: 106582:LOC101468559
uniprot id: A0A3P9BUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:LOC101484667
gene id: 106582:LOC101484667
uniprot id: A0A3P9B0C4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486723
gene id: 106582:LOC101486723
uniprot id: A0A3P9BU72
uniprot id: A0A3P9BUV9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

106582:washc5
gene id: 106582:washc5
uniprot id: A0A3P9BCT8
names: Similarity
messages: Belongs to the strumpellin family.

106582:gatad1
gene id: 106582:gatad1
uniprot id: A0A3P9B6L3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101465170
gene id: 106582:LOC101465170
uniprot id: A0A3P9ATC2
uniprot id: A0A3P9AU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

106582:tmem38b
gene id: 106582:tmem38b
uniprot id: A0A3P9CVE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

106582:LOC101485486
gene id: 106582:LOC101485486
uniprot id: A0A3P9CHA6
uniprot id: A0A3P9CHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

106582:paxbp1
gene id: 106582:paxbp1
uniprot id: A0A3P9CUA5
names: Similarity
messages: Belongs to the GCF family.

106582:fam234a
gene id: 106582:fam234a
uniprot id: A0A3P9BXP9
names: Similarity
messages: Belongs to the FAM234 family.

106582:gtpbp8
gene id: 106582:gtpbp8
uniprot id: A0A3P9C5B3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

106582:LOC101467997
gene id: 106582:LOC101467997
uniprot id: A0A3P9BKR4
names: Subcellular Location Annotation
messages: Membrane

106582:snx25
gene id: 106582:snx25
uniprot id: A0A3P9B9R3
names: Similarity
messages: Belongs to the sorting nexin family.

106582:fuca1
gene id: 106582:fuca1
uniprot id: A0A3P9BX52
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

106582:LOC101471797
gene id: 106582:LOC101471797
uniprot id: A0A3P9AZA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106582:hspa14
gene id: 106582:hspa14
uniprot id: A0A3P9CTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

106582:fgf16
gene id: 106582:fgf16
uniprot id: A0A3P9BZS3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101475601
gene id: 106582:LOC101475601
uniprot id: A0A3P9CK27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

106582:LOC101463945
gene id: 106582:LOC101463945
uniprot id: A0A3P9D9D3
names: Similarity
messages: Belongs to the IL-17 family.

106582:mdm4
gene id: 106582:mdm4
uniprot id: A0A3P9ARV6
uniprot id: A0A3P9AS22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

106582:atp6v1d
gene id: 106582:atp6v1d
uniprot id: A0A3P9AWU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

106582:LOC101480431
gene id: 106582:LOC101480431
uniprot id: A0A3P9C8K7
names: Similarity
messages: Belongs to the phospholipase D family.

106582:cap2
gene id: 106582:cap2
uniprot id: A0A3P9B770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

106582:LOC101467156
gene id: 106582:LOC101467156
uniprot id: A0A3P9C048
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

106582:LOC101466162
gene id: 106582:LOC101466162
uniprot id: A0A3P9D9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

106582:LOC101473935
gene id: 106582:LOC101473935
uniprot id: A0A3P9DPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101487884
gene id: 106582:LOC101487884
uniprot id: A0A3P9C589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

106582:parvg
gene id: 106582:parvg
uniprot id: A0A3P9BQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

106582:nudt1
gene id: 106582:nudt1
uniprot id: A0A3P9D6Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

106582:LOC101475875
gene id: 106582:LOC101475875
uniprot id: A0A3P9AR51
names: Similarity
messages: Belongs to the DNase II family.

106582:LOC101487211
gene id: 106582:LOC101487211
uniprot id: A0A3P9AQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

106582:LOC101471991
gene id: 106582:LOC101471991
uniprot id: A0A3P9BPA7
names: Similarity
messages: Belongs to the intermediate filament family.

106582:dusp16
gene id: 106582:dusp16
uniprot id: A0A3P9CQV7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

106582:LOC101472416
gene id: 106582:LOC101472416
uniprot id: A0A3P9DI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

106582:asic2
gene id: 106582:asic2
uniprot id: A0A3P9D870
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:ccdc130
gene id: 106582:ccdc130
uniprot id: A0A3P9CB60
names: Similarity
messages: Belongs to the CWC16 family.

106582:LOC101469671
gene id: 106582:LOC101469671
uniprot id: A0A3P9C6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

106582:LOC101480739
gene id: 106582:LOC101480739
uniprot id: A0A3P9DH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

106582:LOC101484033
gene id: 106582:LOC101484033
uniprot id: A0A3P9B1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

106582:LOC101474205
gene id: 106582:LOC101474205
uniprot id: A0A3P9CF76
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101468946
gene id: 106582:LOC101468946
uniprot id: A0A3P9B7M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

106582:lg12h9orf3
gene id: 106582:lg12h9orf3
uniprot id: A0A3P9BEP5
names: Similarity
messages: Belongs to the peptidase M1 family.

106582:fam13b
gene id: 106582:fam13b
uniprot id: A0A3P9AUI5
names: Similarity
messages: Belongs to the FAM13 family.

106582:LOC101486200
gene id: 106582:LOC101486200
uniprot id: A0A3P9CK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101479761
gene id: 106582:LOC101479761
uniprot id: A0A3P9C329
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

106582:LOC101464387
gene id: 106582:LOC101464387
uniprot id: A0A3P9AWC5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

106582:LOC101477516
gene id: 106582:LOC101477516
uniprot id: A0A3P9B3E7
names: Subcellular Location Annotation
messages: Nucleus

106582:notch1
gene id: 106582:notch1
uniprot id: A0A3P9AZ26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

106582:fam167b
gene id: 106582:fam167b
uniprot id: A0A3P9BER7
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

106582:mef2a
gene id: 106582:mef2a
uniprot id: A0A3P9D1S8
uniprot id: A0A3P9D1U9
uniprot id: A0A3P9D2X8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101464117
gene id: 106582:LOC101464117
uniprot id: A0A3P9CKG5
uniprot id: A0A3P9CKI9
uniprot id: A0A3P9CKK0
uniprot id: A0A3P9CL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

106582:gmfb
gene id: 106582:gmfb
uniprot id: A0A3P9BV54
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

106582:rybp
gene id: 106582:rybp
uniprot id: A0A3P9BNT5
names: Subcellular Location Annotation
messages: Nucleus

106582:pfdn1
gene id: 106582:pfdn1
uniprot id: A0A3P9DGW9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

106582:nat10
gene id: 106582:nat10
uniprot id: A0A3P9B9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

106582:LOC101467057
gene id: 106582:LOC101467057
uniprot id: A0A3P9C703
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

106582:rb1
gene id: 106582:rb1
uniprot id: A0A3P9CGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

106582:rab14
gene id: 106582:rab14
uniprot id: A0A3P9CS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

106582:fam53b
gene id: 106582:fam53b
uniprot id: A0A3P9AWY7
names: Similarity
messages: Belongs to the FAM53 family.

106582:LOC101475704
gene id: 106582:LOC101475704
uniprot id: A0A3P9C6M7
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

106582:LOC101467378
gene id: 106582:LOC101467378
uniprot id: A0A3P9D183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

106582:LOC101470213
gene id: 106582:LOC101470213
uniprot id: A0A3P9CD71
uniprot id: A0A3P9CD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

106582:LOC101481779
gene id: 106582:LOC101481779
uniprot id: A0A3P9BDV0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

106582:pcolce2
gene id: 106582:pcolce2
uniprot id: A0A3P9D4H7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:fbln5
gene id: 106582:fbln5
uniprot id: A0A3P9BXU3
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101474395
gene id: 106582:LOC101474395
uniprot id: A0A3P9CET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

106582:LOC101474553
gene id: 106582:LOC101474553
uniprot id: A0A3P9BXJ7
uniprot id: A0A3P9BYA4
names: Similarity
messages: Belongs to the CDI family.

106582:LOC101486407
gene id: 106582:LOC101486407
uniprot id: A0A3P9DQE5
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

106582:tm2d3
gene id: 106582:tm2d3
uniprot id: A0A3P9BCA8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469954
gene id: 106582:LOC101469954
uniprot id: A0A3P9BUK5
names: Similarity
messages: Belongs to the PACS family.

106582:LOC101486905
gene id: 106582:LOC101486905
uniprot id: A0A3P9CAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101484519
gene id: 106582:LOC101484519
uniprot id: A0A3P9CWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

106582:suclg2
gene id: 106582:suclg2
uniprot id: A0A3P9C021
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

106582:kansl2
gene id: 106582:kansl2
uniprot id: A0A3P9DB08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

106582:gdf5
gene id: 106582:gdf5
uniprot id: A0A3P9BPZ0
names: Similarity
messages: Belongs to the TGF-beta family.

106582:dyrk2
gene id: 106582:dyrk2
uniprot id: A0A3P9CVB4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

106582:ppp2r5b
gene id: 106582:ppp2r5b
uniprot id: A0A3P9B2X2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

106582:LOC101474466
gene id: 106582:LOC101474466
uniprot id: A0A3P9BX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:marcks
gene id: 106582:marcks
uniprot id: A0A3P9CFM9
names: Similarity
messages: Belongs to the MARCKS family.

106582:basp1
gene id: 106582:basp1
uniprot id: A0A3P9ARW6
names: Similarity
messages: Belongs to the BASP1 family.

106582:LOC101481950
gene id: 106582:LOC101481950
uniprot id: A0A3P9D861
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

106582:serf2
gene id: 106582:serf2
uniprot id: A0A3P9BP65
names: Similarity
messages: Belongs to the SERF family.

106582:tapt1
gene id: 106582:tapt1
uniprot id: A0A3P9BLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

106582:LOC101474875
gene id: 106582:LOC101474875
uniprot id: A0A3P9CTB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

106582:LOC101470030
gene id: 106582:LOC101470030
uniprot id: A0A3P9DCY4
uniprot id: A0A3P9DDG4
uniprot id: A0A3P9DDV4
uniprot id: A0A3P9DEH4
names: Similarity
messages: Belongs to the apolipoprotein L family.

106582:LOC101470970
gene id: 106582:LOC101470970
uniprot id: A0A3P9DMW4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

106582:actc1
gene id: 106582:actc1
uniprot id: A0A3P9AZH7
names: Similarity
messages: Belongs to the actin family.

106582:LOC101479701
gene id: 106582:LOC101479701
uniprot id: A0A3P9ARN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

106582:LOC101485069
gene id: 106582:LOC101485069
uniprot id: A0A3P9D668
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:LOC101472018
gene id: 106582:LOC101472018
uniprot id: A0A3P9BAE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:hspb7
gene id: 106582:hspb7
uniprot id: A0A3P9D2N9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106582:LOC101481198
gene id: 106582:LOC101481198
uniprot id: A0A3P9BM71
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

106582:psmb2
gene id: 106582:psmb2
uniprot id: A0A3P9DLG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

106582:hdx
gene id: 106582:hdx
uniprot id: A0A3P9BHF7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482861
gene id: 106582:LOC101482861
uniprot id: A0A3P9ATM5
names: Similarity
messages: Belongs to the arrestin family.

106582:LOC101473472
gene id: 106582:LOC101473472
uniprot id: A0A3P9BQW0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
messages: extracellular space

106582:LOC101470072
gene id: 106582:LOC101470072
uniprot id: A0A3P9CUI6
names: Similarity
messages: Belongs to the type II (or gamma) interferon family.

106582:pan2
gene id: 106582:pan2
uniprot id: A0A3P9DMQ7
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

106582:cdx4
gene id: 106582:cdx4
uniprot id: A0A3P9BBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

106582:mfap1
gene id: 106582:mfap1
uniprot id: A0A3P9CGD8
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

106582:slc35e4
gene id: 106582:slc35e4
uniprot id: A0A3P9CQE3
names: Subcellular Location Annotation
messages: Membrane

106582:ggt7
gene id: 106582:ggt7
uniprot id: A0A3P9DN83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

106582:tpd52l2
gene id: 106582:tpd52l2
uniprot id: A0A3P9DP28
names: Similarity
messages: Belongs to the TPD52 family.

106582:LOC101476595
gene id: 106582:LOC101476595
uniprot id: A0A3P9BLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

106582:atp6v0a1
gene id: 106582:atp6v0a1
uniprot id: A0A3P9D7W4
uniprot id: A0A3P9D8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

106582:LOC101474073
gene id: 106582:LOC101474073
uniprot id: A0A3P9C990
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC101482735
gene id: 106582:LOC101482735
uniprot id: A0A3P9AS23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

106582:gba
gene id: 106582:gba
uniprot id: A0A3P9CH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

106582:tbx20
gene id: 106582:tbx20
uniprot id: A0A3P9CD58
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:thumpd2
gene id: 106582:thumpd2
uniprot id: A0A3P9DRC3
names: Similarity
messages: Belongs to the methyltransferase superfamily.

106582:LOC101466166
gene id: 106582:LOC101466166
uniprot id: A0A3P9BRQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

106582:endog
gene id: 106582:endog
uniprot id: A0A3P9D017
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

106582:LOC101474680
gene id: 106582:LOC101474680
uniprot id: A0A3P9CR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

106582:gbx1
gene id: 106582:gbx1
uniprot id: A0A3P9DFP4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101487922
gene id: 106582:LOC101487922
uniprot id: A0A3P9DGA2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:LOC101483941
gene id: 106582:LOC101483941
uniprot id: A0A3P9D0Z3
names: Subcellular Location Annotation
messages: Nucleus

106582:syt14
gene id: 106582:syt14
uniprot id: A0A3P9BGV9
names: Similarity
messages: Belongs to the synaptotagmin family.

106582:glo1
gene id: 106582:glo1
uniprot id: A0A3P9B8Z5
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

106582:LOC101475133
gene id: 106582:LOC101475133
uniprot id: A0A3P9C5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

106582:LOC101471318
gene id: 106582:LOC101471318
uniprot id: A0A3P9D3D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:mrpl52
gene id: 106582:mrpl52
uniprot id: A0A3P9D0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

106582:LOC101466501
gene id: 106582:LOC101466501
uniprot id: A0A3P9CI47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101478974
gene id: 106582:LOC101478974
uniprot id: A0A3P9D032
names: Subcellular Location Annotation
messages: Nucleus

106582:spc25
gene id: 106582:spc25
uniprot id: A0A3P9BDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

106582:LOC101472406
gene id: 106582:LOC101472406
uniprot id: A0A3P9D477
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101468274
gene id: 106582:LOC101468274
uniprot id: A0A3P9C111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

106582:mars2
gene id: 106582:mars2
uniprot id: A0A3P9BMU5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:npy
gene id: 106582:npy
uniprot id: A0A3P9BQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

106582:LOC101473310
gene id: 106582:LOC101473310
uniprot id: A0A3P9B6N4
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

106582:pfdn4
gene id: 106582:pfdn4
uniprot id: A0A3P9DB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

106582:ppp5c
gene id: 106582:ppp5c
uniprot id: A0A3P9DDZ7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

106582:LOC101469157
gene id: 106582:LOC101469157
uniprot id: A0A3P9B9U7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101467337
gene id: 106582:LOC101467337
uniprot id: A0A3P9AX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:usp49
gene id: 106582:usp49
uniprot id: A0A3P9BYC8
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:mrps18b
gene id: 106582:mrps18b
uniprot id: A0A3P9CNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

106582:med18
gene id: 106582:med18
uniprot id: A0A3P9B5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:scnm1
gene id: 106582:scnm1
uniprot id: A0A3P9BVI9
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

106582:pigh
gene id: 106582:pigh
uniprot id: A0A3P9C576
names: Similarity
messages: Belongs to the PIGH family.

106582:LOC101477431
gene id: 106582:LOC101477431
uniprot id: A0A3P9BQA1
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106582:gins1
gene id: 106582:gins1
uniprot id: A0A3P9B601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

106582:lg17h1orf52
gene id: 106582:lg17h1orf52
uniprot id: A0A3P9BGT2
names: Similarity
messages: Belongs to the UPF0690 family.

106582:LOC105941172
gene id: 106582:LOC105941172
uniprot id: A0A3P9BRT6
names: Similarity
messages: Belongs to the p23/wos2 family.

106582:lhx3
gene id: 106582:lhx3
uniprot id: A0A3P9CV12
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478548
gene id: 106582:LOC101478548
uniprot id: A0A3P9BFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

106582:LOC101468235
gene id: 106582:LOC101468235
uniprot id: A0A3P9C4G2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101481185
gene id: 106582:LOC101481185
uniprot id: A0A3P9CRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101467797
gene id: 106582:LOC101467797
uniprot id: A0A3P9BM83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

106582:ipmk
gene id: 106582:ipmk
uniprot id: A0A3P9B2P6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

106582:LOC101468971
gene id: 106582:LOC101468971
uniprot id: A0A3P9BWW1
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476960
gene id: 106582:LOC101476960
uniprot id: A0A3P9BP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:hoga1
gene id: 106582:hoga1
uniprot id: A0A3P9CAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

106582:slc35d1
gene id: 106582:slc35d1
uniprot id: A0A3P9CX66
names: Subcellular Location Annotation
messages: Membrane

106582:ptpn11
gene id: 106582:ptpn11
uniprot id: A0A3P9BLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

106582:LOC101474159
gene id: 106582:LOC101474159
uniprot id: A0A3P9ATQ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:LOC101482598
gene id: 106582:LOC101482598
uniprot id: A0A3P9B475
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469419
gene id: 106582:LOC101469419
uniprot id: A0A3P9BUJ3
uniprot id: A0A3P9BUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101482952
gene id: 106582:LOC101482952
uniprot id: A0A3P9C1M1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

106582:cacul1
gene id: 106582:cacul1
uniprot id: A0A3P9BZ13
names: Similarity
messages: Belongs to the cullin family.

106582:gje1
gene id: 106582:gje1
uniprot id: A0A3P9C9I7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101485665
gene id: 106582:LOC101485665
uniprot id: A0A3P9B6J4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:amotl2
gene id: 106582:amotl2
uniprot id: A0A3P9BPV1
names: Similarity
messages: Belongs to the angiomotin family.

106582:ndufa13
gene id: 106582:ndufa13
uniprot id: A0A3P9DIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

106582:rogdi
gene id: 106582:rogdi
uniprot id: A0A3P9D7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

106582:LOC101478994
gene id: 106582:LOC101478994
uniprot id: A0A3P9AY15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:pros1
gene id: 106582:pros1
uniprot id: A0A3P9B1F7
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101487673
gene id: 106582:LOC101487673
uniprot id: A0A3P9C365
names: Similarity
messages: Belongs to the PIAS family.

106582:LOC101486852
gene id: 106582:LOC101486852
uniprot id: A0A3P9DPL3
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101475395
gene id: 106582:LOC101475395
uniprot id: A0A3P9C424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

106582:LOC101487230
gene id: 106582:LOC101487230
uniprot id: A0A3P9CHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

106582:tbcb
gene id: 106582:tbcb
uniprot id: A0A3P9CJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCB family.
messages: Cytoplasm

106582:LOC101478664
gene id: 106582:LOC101478664
uniprot id: A0A3P9C730
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

106582:LOC101471372
gene id: 106582:LOC101471372
uniprot id: A0A3P9CAR4
names: Similarity
messages: Belongs to the NXPE family.

106582:kif27
gene id: 106582:kif27
uniprot id: A0A3P9B880
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:LOC101481918
gene id: 106582:LOC101481918
uniprot id: A0A3P9C6S7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

106582:usp5
gene id: 106582:usp5
uniprot id: A0A3P9CPD5
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:atf1
gene id: 106582:atf1
uniprot id: A0A3P9BJJ1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472879
gene id: 106582:LOC101472879
uniprot id: A0A3P9BQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

106582:LOC101478350
gene id: 106582:LOC101478350
uniprot id: A0A3P9BQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

106582:slc6a9
gene id: 106582:slc6a9
uniprot id: A0A3P9CA83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

106582:ccdc25
gene id: 106582:ccdc25
uniprot id: A0A3P9BB72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

106582:ppie
gene id: 106582:ppie
uniprot id: A0A3P9BDS0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

106582:LOC101474425
gene id: 106582:LOC101474425
uniprot id: A0A3P9DFC8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101482120
gene id: 106582:LOC101482120
uniprot id: A0A3P9CPV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

106582:mis18a
gene id: 106582:mis18a
uniprot id: A0A3P9DDW8
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

106582:tsfm
gene id: 106582:tsfm
uniprot id: A0A3P9BLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

106582:spsb4
gene id: 106582:spsb4
uniprot id: A0A3P9B8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

106582:LOC101473203
gene id: 106582:LOC101473203
uniprot id: A0A3P9DLN5
names: Similarity
messages: Belongs to the PPP4R2 family.

106582:LOC101480585
gene id: 106582:LOC101480585
uniprot id: A0A3P9C6A8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:nmb
gene id: 106582:nmb
uniprot id: A0A3P9BPU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

106582:ints2
gene id: 106582:ints2
uniprot id: A0A3P9D9S7
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

106582:LOC101483765
gene id: 106582:LOC101483765
uniprot id: A0A3P9BWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

106582:LOC101465041
gene id: 106582:LOC101465041
uniprot id: A0A3P9BDN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

106582:ovca2
gene id: 106582:ovca2
uniprot id: A0A3P9DG84
names: Similarity
messages: Belongs to the LovG family.

106582:LOC101485847
gene id: 106582:LOC101485847
uniprot id: A0A3P9DD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

106582:eva1a
gene id: 106582:eva1a
uniprot id: A0A3P9CQE4
uniprot id: A0A3P9CR42
names: Similarity
messages: Belongs to the EVA1 family.

106582:LOC101476248
gene id: 106582:LOC101476248
uniprot id: A0A3P9DDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

106582:lg15h12orf57
gene id: 106582:lg15h12orf57
uniprot id: A0A3P9AZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

106582:cers6
gene id: 106582:cers6
uniprot id: A0A3P9BE72
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

106582:LOC101479964
gene id: 106582:LOC101479964
uniprot id: A0A3P9BQL6
names: Subcellular Location Annotation
messages: Nucleus

106582:orc1
gene id: 106582:orc1
uniprot id: A0A3P9CP98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

106582:tmem206
gene id: 106582:tmem206
uniprot id: A0A3P9C120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

106582:LOC101486160
gene id: 106582:LOC101486160
uniprot id: A0A3P9BUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:ccser1
gene id: 106582:ccser1
uniprot id: A0A3P9B9R6
names: Similarity
messages: Belongs to the CCSER family.

106582:ddit4
gene id: 106582:ddit4
uniprot id: A0A3P9AUD5
names: Similarity
messages: Belongs to the DDIT4 family.

106582:cdca8
gene id: 106582:cdca8
uniprot id: A0A3P9DLQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

106582:LOC101469740
gene id: 106582:LOC101469740
uniprot id: A0A3P9CU76
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:atg101
gene id: 106582:atg101
uniprot id: A0A3P9D9L1
names: Similarity
messages: Belongs to the ATG101 family.

106582:mrpl47
gene id: 106582:mrpl47
uniprot id: A0A3P9AYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

106582:LOC101471468
gene id: 106582:LOC101471468
uniprot id: A0A3P9B5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:ust
gene id: 106582:ust
uniprot id: A0A3P9CNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

106582:gabarap
gene id: 106582:gabarap
uniprot id: A0A3P9D4M7
names: Similarity
messages: Belongs to the ATG8 family.

106582:LOC101465379
gene id: 106582:LOC101465379
uniprot id: A0A3P9DEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:LOC101465259
gene id: 106582:LOC101465259
uniprot id: A0A3P9DET6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

106582:flcn
gene id: 106582:flcn
uniprot id: A0A3P9CHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

106582:LOC101468573
gene id: 106582:LOC101468573
uniprot id: A0A3P9D5T0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

106582:eif3h
gene id: 106582:eif3h
uniprot id: A0A3P9BD67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

106582:LOC101485544
gene id: 106582:LOC101485544
uniprot id: A0A3P9CCQ1
names: Similarity
messages: Belongs to the SMARCD family.

106582:nkx2-5
gene id: 106582:nkx2-5
uniprot id: A0A3P9BPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

106582:nsun2
gene id: 106582:nsun2
uniprot id: A0A3P9AQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

106582:bud23
gene id: 106582:bud23
uniprot id: A0A3P9CIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101465039
gene id: 106582:LOC101465039
uniprot id: A0A3P9C4A1
names: Similarity
messages: Belongs to the BTG family.

106582:tmem167b
gene id: 106582:tmem167b
uniprot id: A0A3P9DPL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:evx2
gene id: 106582:evx2
uniprot id: A0A3P9B8M3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101463685
gene id: 106582:LOC101463685
uniprot id: A0A3P9B9C3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

106582:LOC101472882
gene id: 106582:LOC101472882
uniprot id: A0A3P9BE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

106582:mtg2
gene id: 106582:mtg2
uniprot id: A0A3P9DKT4
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

106582:LOC101484002
gene id: 106582:LOC101484002
uniprot id: A0A3P9BPF4
uniprot id: A0A3P9BQA4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

106582:LOC101486390
gene id: 106582:LOC101486390
uniprot id: A0A3P9BLH3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106582:atg9a
gene id: 106582:atg9a
uniprot id: A0A3P9AW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

106582:fez1
gene id: 106582:fez1
uniprot id: A0A3P9DAS5
names: Similarity
messages: Belongs to the zygin family.

106582:apip
gene id: 106582:apip
uniprot id: A0A3P9CAC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

106582:tmem18
gene id: 106582:tmem18
uniprot id: A0A3P9CKH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

106582:LOC101476773
gene id: 106582:LOC101476773
uniprot id: A0A3P9AU76
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

106582:pi4k2a
gene id: 106582:pi4k2a
uniprot id: A0A3P9BH74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

106582:LOC101477863
gene id: 106582:LOC101477863
uniprot id: A0A3P9DC15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

106582:LOC101479763
gene id: 106582:LOC101479763
uniprot id: A0A3P9BPR6
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101486097
gene id: 106582:LOC101486097
uniprot id: A0A3P9D564
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101466386
gene id: 106582:LOC101466386
uniprot id: A0A3P9BYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

106582:LOC101472310
gene id: 106582:LOC101472310
uniprot id: A0A3P9DFG8
names: Subcellular Location Annotation
messages: Membrane

106582:dclre1b
gene id: 106582:dclre1b
uniprot id: A0A3P9BEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

106582:tp53i11
gene id: 106582:tp53i11
uniprot id: A0A3P9BAN4
names: Subcellular Location Annotation
messages: Membrane

106582:rnf157
gene id: 106582:rnf157
uniprot id: A0A3P9B6E4
uniprot id: A0A3P9B6H8
uniprot id: A0A3P9B6N3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

106582:LOC101466310
gene id: 106582:LOC101466310
uniprot id: A0A3P9C6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

106582:mpdu1
gene id: 106582:mpdu1
uniprot id: A0A3P9BSK3
names: Subcellular Location Annotation
messages: Membrane

106582:spon1
gene id: 106582:spon1
uniprot id: A0A3P9C2W8
names: Subcellular Location Annotation
messages: extracellular matrix

106582:cacfd1
gene id: 106582:cacfd1
uniprot id: A0A3P9B444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

106582:LOC101473495
gene id: 106582:LOC101473495
uniprot id: A0A3P9DLA3
uniprot id: A0A3P9DLP0
names: Subcellular Location Annotation
messages: Nucleus

106582:lg10h11orf87
gene id: 106582:lg10h11orf87
uniprot id: A0A3P9BUC8
names: Subcellular Location Annotation
messages: Membrane

106582:fermt2
gene id: 106582:fermt2
uniprot id: A0A3P9AYQ7
uniprot id: A0A3P9AYQ8
uniprot id: A0A3P9AYT1
names: Similarity
messages: Belongs to the kindlin family.

106582:LOC101483194
gene id: 106582:LOC101483194
uniprot id: A0A3P9D6D1
uniprot id: A0A3P9D7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

106582:LOC101486184
gene id: 106582:LOC101486184
uniprot id: A0A3P9D8R0
uniprot id: A0A3P9D8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:med25
gene id: 106582:med25
uniprot id: A0A3P9D8X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

106582:gbe1
gene id: 106582:gbe1
uniprot id: A0A3P9DBY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

106582:LOC101476084
gene id: 106582:LOC101476084
uniprot id: A0A3P9DGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

106582:LOC101478942
gene id: 106582:LOC101478942
uniprot id: A0A3P9B3I4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101485759
gene id: 106582:LOC101485759
uniprot id: A0A3P9BGX9
uniprot id: A0A3P9BH18
uniprot id: A0A3P9BHK7
uniprot id: A0A3P9BHN6
uniprot id: A0A3P9BHS2
names: Similarity
messages: Belongs to the BRAG family.

106582:LOC101466249
gene id: 106582:LOC101466249
uniprot id: A0A3P9CSQ1
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101479734
gene id: 106582:LOC101479734
uniprot id: A0A3P9D8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

106582:nadsyn1
gene id: 106582:nadsyn1
uniprot id: A0A3P9B0K6
uniprot id: A0A3P9B0M2
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

106582:LOC101475274
gene id: 106582:LOC101475274
uniprot id: A0A3P9CXD5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:LOC101466126
gene id: 106582:LOC101466126
uniprot id: A0A3P9C945
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:surf6
gene id: 106582:surf6
uniprot id: A0A3P9B2Y0
names: Similarity
messages: Belongs to the SURF6 family.

106582:ube2g1
gene id: 106582:ube2g1
uniprot id: A0A3P9DAN5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101486595
gene id: 106582:LOC101486595
uniprot id: A0A3P9B2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

106582:dpf2
gene id: 106582:dpf2
uniprot id: A0A3P9B6E7
names: Similarity
messages: Belongs to the requiem/DPF family.

106582:p3h1
gene id: 106582:p3h1
uniprot id: A0A3P9BIR4
names: Similarity
messages: Belongs to the leprecan family.

106582:xylt1
gene id: 106582:xylt1
uniprot id: A0A3P9BRU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

106582:hus1
gene id: 106582:hus1
uniprot id: A0A3P9CXW6
names: Similarity
messages: Belongs to the HUS1 family.

106582:LOC101483674
gene id: 106582:LOC101483674
uniprot id: A0A3P9DQL3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

106582:LOC101483021
gene id: 106582:LOC101483021
uniprot id: A0A3P9B2J2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

106582:lg7h5orf30
gene id: 106582:lg7h5orf30
uniprot id: A0A3P9BXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

106582:cul9
gene id: 106582:cul9
uniprot id: A0A3P9AZU9
uniprot id: A0A3P9AZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

106582:cct4
gene id: 106582:cct4
uniprot id: A0A3P9BA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

106582:rpl36
gene id: 106582:rpl36
uniprot id: A0A3P9CQD8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

106582:LOC101478284
gene id: 106582:LOC101478284
uniprot id: A0A3P9BWR3
uniprot id: A0A3P9BX18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106582:LOC101478748
gene id: 106582:LOC101478748
uniprot id: A0A3P9BBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

106582:tmem88b
gene id: 106582:tmem88b
uniprot id: A0A3P9BY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

106582:LOC101477468
gene id: 106582:LOC101477468
uniprot id: A0A3P9AXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

106582:echdc2
gene id: 106582:echdc2
uniprot id: A0A3P9CV71
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

106582:LOC101475506
gene id: 106582:LOC101475506
uniprot id: A0A3P9BX05
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

106582:LOC101478226
gene id: 106582:LOC101478226
uniprot id: A0A3P9B1V0
names: Subcellular Location Annotation
messages: extracellular space

106582:ids
gene id: 106582:ids
uniprot id: A0A3P9BBD6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

106582:osgep
gene id: 106582:osgep
uniprot id: A0A3P9C9B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

106582:tubgcp2
gene id: 106582:tubgcp2
uniprot id: A0A3P9BNQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

106582:anxa1
gene id: 106582:anxa1
uniprot id: A0A3P9BW76
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: cilium

106582:LOC101483023
gene id: 106582:LOC101483023
uniprot id: A0A3P9BD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:cops2
gene id: 106582:cops2
uniprot id: A0A3P9C1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101465072
gene id: 106582:LOC101465072
uniprot id: A0A3P9CZA6
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101486333
gene id: 106582:LOC101486333
uniprot id: A0A3P9DEM4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:gba2
gene id: 106582:gba2
uniprot id: A0A3P9D0K0
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

106582:LOC101484486
gene id: 106582:LOC101484486
uniprot id: A0A3P9BV08
names: Similarity
messages: Belongs to the FAM83 family.

106582:LOC101472597
gene id: 106582:LOC101472597
uniprot id: A0A3P9BE65
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101465102
gene id: 106582:LOC101465102
uniprot id: A0A3P9C3B0
uniprot id: A0A3P9C3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

106582:vkorc1l1
gene id: 106582:vkorc1l1
uniprot id: A0A3P9DCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:sufu
gene id: 106582:sufu
uniprot id: A0A3P9B289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

106582:slco2b1
gene id: 106582:slco2b1
uniprot id: A0A3P9DGY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

106582:LOC101479270
gene id: 106582:LOC101479270
uniprot id: A0A3P9CRH6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:acvr1
gene id: 106582:acvr1
uniprot id: A0A3P9BNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:coq8a
gene id: 106582:coq8a
uniprot id: A0A3P9C3W4
uniprot id: A0A3P9C3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

106582:rbpms2
gene id: 106582:rbpms2
uniprot id: A0A3P9C7M8
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101473861
gene id: 106582:LOC101473861
uniprot id: A0A3P9B3J5
names: Similarity
messages: Belongs to the peptidase S28 family.

106582:mtfr2
gene id: 106582:mtfr2
uniprot id: A0A3P9CFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

106582:tfb2m
gene id: 106582:tfb2m
uniprot id: A0A3P9BW84
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

106582:cog2
gene id: 106582:cog2
uniprot id: A0A3P9DQV5
names: Similarity
messages: Belongs to the COG2 family.

106582:arl6ip4
gene id: 106582:arl6ip4
uniprot id: A0A3P9ATB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

106582:mterf1
gene id: 106582:mterf1
uniprot id: A0A3P9DNA4
names: Similarity
messages: Belongs to the mTERF family.

106582:LOC101469976
gene id: 106582:LOC101469976
uniprot id: A0A3P9CDQ8
names: Similarity
messages: Belongs to the stathmin family.

106582:nme6
gene id: 106582:nme6
uniprot id: A0A3P9CGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

106582:ddit4l
gene id: 106582:ddit4l
uniprot id: A0A3P9B0D1
names: Similarity
messages: Belongs to the DDIT4 family.

106582:rack1
gene id: 106582:rack1
uniprot id: A0A3P9C369
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

106582:acot8
gene id: 106582:acot8
uniprot id: A0A3P9BLY7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

106582:LOC101478464
gene id: 106582:LOC101478464
uniprot id: A0A3P9CMX7
names: Similarity
messages: Belongs to the GORASP family.

106582:cc2d1a
gene id: 106582:cc2d1a
uniprot id: A0A3P9BJM8
names: Similarity
messages: Belongs to the CC2D1 family.

106582:LOC101471582
gene id: 106582:LOC101471582
uniprot id: A0A3P9DA86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

106582:LOC101481788
gene id: 106582:LOC101481788
uniprot id: A0A3P9BQU4
names: Subcellular Location Annotation
messages: Nucleus

106582:eif2a
gene id: 106582:eif2a
uniprot id: A0A3P9AXB8
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

106582:LOC101473508
gene id: 106582:LOC101473508
uniprot id: A0A3P9ATP1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

106582:LOC101484899
gene id: 106582:LOC101484899
uniprot id: A0A3P9DGX6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

106582:LOC101466338
gene id: 106582:LOC101466338
uniprot id: A0A3P9BCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:hnrnpul1
gene id: 106582:hnrnpul1
uniprot id: A0A3P9DDA8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101474440
gene id: 106582:LOC101474440
uniprot id: A0A3P9BE05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

106582:pigc
gene id: 106582:pigc
uniprot id: A0A3P9CVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

106582:LOC101481248
gene id: 106582:LOC101481248
uniprot id: A0A3P9CCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

106582:mmaa
gene id: 106582:mmaa
uniprot id: A0A3P9BRJ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

106582:LOC101483346
gene id: 106582:LOC101483346
uniprot id: A0A3P9BU71
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

106582:blk
gene id: 106582:blk
uniprot id: A0A3P9CH91
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:sephs1
gene id: 106582:sephs1
uniprot id: A0A3P9CUK9
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

106582:slc25a14
gene id: 106582:slc25a14
uniprot id: A0A3P9C1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101475843
gene id: 106582:LOC101475843
uniprot id: A0A3P9C072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:ss18
gene id: 106582:ss18
uniprot id: A0A3P9DHS5
uniprot id: A0A3P9DIC6
uniprot id: A0A3P9DIG6
names: Similarity
messages: Belongs to the SS18 family.

106582:LOC101475243
gene id: 106582:LOC101475243
uniprot id: A0A3P9B205
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

106582:LOC101467613
gene id: 106582:LOC101467613
uniprot id: A0A3P9C5C3
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

106582:nr1h4
gene id: 106582:nr1h4
uniprot id: A0A3P9CTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:LOC101480282
gene id: 106582:LOC101480282
uniprot id: A0A3P9DMJ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:btf3
gene id: 106582:btf3
uniprot id: A0A3P9B821
names: Similarity
messages: Belongs to the NAC-beta family.

106582:orc5
gene id: 106582:orc5
uniprot id: A0A3P9B2V9
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101485731
gene id: 106582:LOC101485731
uniprot id: A0A3P9DSD9
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

106582:LOC101474113
gene id: 106582:LOC101474113
uniprot id: A0A3P9DRU0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:tube1
gene id: 106582:tube1
uniprot id: A0A3P9CFT6
names: Similarity
messages: Belongs to the tubulin family.

106582:LOC101469131
gene id: 106582:LOC101469131
uniprot id: A0A3P9BUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:castor1
gene id: 106582:castor1
uniprot id: A0A3P9CBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

106582:LOC101479778
gene id: 106582:LOC101479778
uniprot id: A0A3P9BZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:kcnd3
gene id: 106582:kcnd3
uniprot id: A0A3P9DND2
uniprot id: A0A3P9DPW2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

106582:spc24
gene id: 106582:spc24
uniprot id: A0A3P9B5M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

106582:LOC101469754
gene id: 106582:LOC101469754
uniprot id: A0A3P9BJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101480893
gene id: 106582:LOC101480893
uniprot id: A0A3P9BD61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

106582:sirt4
gene id: 106582:sirt4
uniprot id: A0A3P9C7N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

106582:pip4p1
gene id: 106582:pip4p1
uniprot id: A0A3P9DDA0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

106582:rab27a
gene id: 106582:rab27a
uniprot id: A0A3P9C5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

106582:apaf1
gene id: 106582:apaf1
uniprot id: A0A3P9BAD0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

106582:LOC101476058
gene id: 106582:LOC101476058
uniprot id: A0A3P9D6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

106582:slc25a45
gene id: 106582:slc25a45
uniprot id: A0A3P9D2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:exoc2
gene id: 106582:exoc2
uniprot id: A0A3P9CK94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

106582:ccnf
gene id: 106582:ccnf
uniprot id: A0A3P9B8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: centriole
messages: perinuclear region

106582:LOC101478412
gene id: 106582:LOC101478412
uniprot id: A0A3P9D989
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

106582:dohh
gene id: 106582:dohh
uniprot id: A0A3P9CNZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

106582:nsun4
gene id: 106582:nsun4
uniprot id: A0A3P9B6R3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

106582:mcm5
gene id: 106582:mcm5
uniprot id: A0A3P9B657
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

106582:LOC101487532
gene id: 106582:LOC101487532
uniprot id: A0A3P9C2R0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

106582:LOC101486492
gene id: 106582:LOC101486492
uniprot id: A0A3P9DM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

106582:LOC101479064
gene id: 106582:LOC101479064
uniprot id: A0A3P9D6W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

106582:ucma
gene id: 106582:ucma
uniprot id: A0A3P9CE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

106582:LOC101486412
gene id: 106582:LOC101486412
uniprot id: A0A3P9B7G3
names: Subcellular Location Annotation
messages: Membrane

106582:csrnp2
gene id: 106582:csrnp2
uniprot id: A0A3P9DM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

106582:LOC101479404
gene id: 106582:LOC101479404
uniprot id: A0A3P9CTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

106582:LOC101471528
gene id: 106582:LOC101471528
uniprot id: A0A3P9C2F6
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101477803
gene id: 106582:LOC101477803
uniprot id: A0A3P9B010
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101484677
gene id: 106582:LOC101484677
uniprot id: A0A3P9D820
names: Similarity
messages: Belongs to the myozenin family.

106582:LOC101487688
gene id: 106582:LOC101487688
uniprot id: A0A3P9CDQ3
uniprot id: A0A3P9CEF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

106582:LOC101486173
gene id: 106582:LOC101486173
uniprot id: A0A3P9DFJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101473738
gene id: 106582:LOC101473738
uniprot id: A0A3P9CPB0
names: Similarity
messages: Belongs to the peptidase M10A family.

106582:p2ry4
gene id: 106582:p2ry4
uniprot id: A0A3P9BDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101484997
gene id: 106582:LOC101484997
uniprot id: A0A3P9BDW7
names: Similarity
messages: Belongs to the dpy-30 family.

106582:acads
gene id: 106582:acads
uniprot id: A0A3P9C163
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106582:fut8
gene id: 106582:fut8
uniprot id: A0A3P9AWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

106582:LOC101476821
gene id: 106582:LOC101476821
uniprot id: A0A3P9BFN5
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101471453
gene id: 106582:LOC101471453
uniprot id: A0A3P9AWM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:gng4
gene id: 106582:gng4
uniprot id: A0A3P9BTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101472984
gene id: 106582:LOC101472984
uniprot id: A0A3P9CC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

106582:gdnf
gene id: 106582:gdnf
uniprot id: A0A3P9CRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Homodimer; disulfide-linked.
messages: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
messages: Secreted

106582:pitx2
gene id: 106582:pitx2
uniprot id: A0A3P9AVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

106582:homer1
gene id: 106582:homer1
uniprot id: A0A3P9BDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

106582:LOC101477525
gene id: 106582:LOC101477525
uniprot id: A0A3P9CL08
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

106582:LOC101463809
gene id: 106582:LOC101463809
uniprot id: A0A3P9BB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

106582:LOC101487398
gene id: 106582:LOC101487398
uniprot id: A0A3P9CQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101468938
gene id: 106582:LOC101468938
uniprot id: A0A3P9C4R1
names: Subcellular Location Annotation
messages: Nucleus

106582:nat9
gene id: 106582:nat9
uniprot id: A0A3P9B7H4
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

106582:mrps30
gene id: 106582:mrps30
uniprot id: A0A3P9C824
names: Subcellular Location Annotation
messages: Mitochondrion

106582:tnip2
gene id: 106582:tnip2
uniprot id: A0A3P9BXQ9
names: Subcellular Location Annotation
messages: Cytoplasm

106582:krr1
gene id: 106582:krr1
uniprot id: A0A3P9BM95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

106582:cav2
gene id: 106582:cav2
uniprot id: A0A3P9C6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

106582:LOC101480891
gene id: 106582:LOC101480891
uniprot id: A0A3P9CX40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:tnfaip6
gene id: 106582:tnfaip6
uniprot id: A0A3P9D0H5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101483147
gene id: 106582:LOC101483147
uniprot id: A0A3P9BP18
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:mrpl46
gene id: 106582:mrpl46
uniprot id: A0A3P9B9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

106582:LOC101487602
gene id: 106582:LOC101487602
uniprot id: A0A3P9BPH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

106582:ddx55
gene id: 106582:ddx55
uniprot id: A0A3P9BLC6
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:LOC101479031
gene id: 106582:LOC101479031
uniprot id: A0A3P9CLM5
uniprot id: A0A3P9CMC3
names: Similarity
messages: Belongs to the TMEM14 family.

106582:LOC101471281
gene id: 106582:LOC101471281
uniprot id: A0A3P9CT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

106582:gstk1
gene id: 106582:gstk1
uniprot id: A0A3P9CMS6
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

106582:LOC101483916
gene id: 106582:LOC101483916
uniprot id: A0A3P9DGQ1
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101468798
gene id: 106582:LOC101468798
uniprot id: A0A3P9C2V1
names: Similarity
messages: Belongs to the pyridoxine kinase family.

106582:LOC101472915
gene id: 106582:LOC101472915
uniprot id: A0A3P9D925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

106582:LOC101483709
gene id: 106582:LOC101483709
uniprot id: A0A3P9BM84
names: Similarity
messages: Belongs to the FAM83 family.

106582:e2f4
gene id: 106582:e2f4
uniprot id: A0A3P9CJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

106582:rpl31
gene id: 106582:rpl31
uniprot id: A0A3P9BIX0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

106582:slc25a47
gene id: 106582:slc25a47
uniprot id: A0A3P9C2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:plrg1
gene id: 106582:plrg1
uniprot id: A0A3P9BH87
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

106582:LOC101474541
gene id: 106582:LOC101474541
uniprot id: A0A3P9C2E8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

106582:cldn1
gene id: 106582:cldn1
uniprot id: A0A3P9DF63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101472272
gene id: 106582:LOC101472272
uniprot id: A0A3P9BH96
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

106582:aplp1
gene id: 106582:aplp1
uniprot id: A0A3P9C4X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101466363
gene id: 106582:LOC101466363
uniprot id: A0A3P9C699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:rpf1
gene id: 106582:rpf1
uniprot id: A0A3P9AR99
names: Subcellular Location Annotation
messages: nucleolus

106582:cep70
gene id: 106582:cep70
uniprot id: A0A3P9D2A9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

106582:rad9a
gene id: 106582:rad9a
uniprot id: A0A3P9B2Q8
names: Similarity
messages: Belongs to the rad9 family.

106582:LOC101469883
gene id: 106582:LOC101469883
uniprot id: A0A3P9CN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

106582:LOC101482596
gene id: 106582:LOC101482596
uniprot id: A0A3P9CIM9
uniprot id: A0A3P9CIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

106582:st8sia5
gene id: 106582:st8sia5
uniprot id: A0A3P9AYQ6
uniprot id: A0A3P9AYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:pih1d1
gene id: 106582:pih1d1
uniprot id: A0A3P9D8M7
names: Similarity
messages: Belongs to the PIH1 family.

106582:eif2s1
gene id: 106582:eif2s1
uniprot id: A0A3P9AVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

106582:cpne2
gene id: 106582:cpne2
uniprot id: A0A3P9BWD5
names: Similarity
messages: Belongs to the copine family.

106582:LOC101481614
gene id: 106582:LOC101481614
uniprot id: A0A3P9BJX0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

106582:usp48
gene id: 106582:usp48
uniprot id: A0A3P9BC43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

106582:mrgbp
gene id: 106582:mrgbp
uniprot id: A0A3P9DNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

106582:LOC101466826
gene id: 106582:LOC101466826
uniprot id: A0A3P9AXC7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101466641
gene id: 106582:LOC101466641
uniprot id: A0A3P9C6C2
names: Similarity
messages: Belongs to the peptidase M14 family.

106582:LOC101476317
gene id: 106582:LOC101476317
uniprot id: A0A3P9CDK9
names: Similarity
messages: Belongs to the SNF7 family.

106582:LOC101475299
gene id: 106582:LOC101475299
uniprot id: A0A3P9D623
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101468418
gene id: 106582:LOC101468418
uniprot id: A0A3P9DNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:cct3
gene id: 106582:cct3
uniprot id: A0A3P9C1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

106582:clgn
gene id: 106582:clgn
uniprot id: A0A3P9BZM5
names: Similarity
messages: Belongs to the calreticulin family.

106582:pcna
gene id: 106582:pcna
uniprot id: A0A3P9BRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

106582:themis2
gene id: 106582:themis2
uniprot id: A0A3P9BG78
names: Similarity
messages: Belongs to the themis family.

106582:pithd1
gene id: 106582:pithd1
uniprot id: A0A3P9DL38
names: Similarity
messages: Belongs to the PITHD1 family.

106582:cbfb
gene id: 106582:cbfb
uniprot id: A0A3P9CHT8
uniprot id: A0A3P9CI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

106582:cth
gene id: 106582:cth
uniprot id: A0A3P9CQ73
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

106582:LOC101474807
gene id: 106582:LOC101474807
uniprot id: A0A3P9CS57
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

106582:LOC101473285
gene id: 106582:LOC101473285
uniprot id: A0A3P9CBC0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:scarb1
gene id: 106582:scarb1
uniprot id: A0A3P9C271
uniprot id: A0A3P9C2K9
uniprot id: A0A3P9C2P2
names: Similarity
messages: Belongs to the CD36 family.

106582:wnt6
gene id: 106582:wnt6
uniprot id: A0A3P9AXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:eef1d
gene id: 106582:eef1d
uniprot id: A0A3P9CKR0
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

106582:LOC101477936
gene id: 106582:LOC101477936
uniprot id: A0A3P9DG98
uniprot id: A0A3P9DH08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

106582:aptx
gene id: 106582:aptx
uniprot id: A0A3P9D7N2
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

106582:LOC101475202
gene id: 106582:LOC101475202
uniprot id: A0A3P9BCW7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

106582:rspo1
gene id: 106582:rspo1
uniprot id: A0A3P9BMH7
names: Similarity
messages: Belongs to the R-spondin family.

106582:atp5f1d
gene id: 106582:atp5f1d
uniprot id: A0A3P9BUH7
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

106582:LOC101478647
gene id: 106582:LOC101478647
uniprot id: A0A3P9CRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

106582:LOC101481184
gene id: 106582:LOC101481184
uniprot id: A0A3P9BKB6
names: Similarity
messages: Belongs to the cullin family.

106582:LOC101487173
gene id: 106582:LOC101487173
uniprot id: A0A3P9C6S3
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

106582:LOC101486339
gene id: 106582:LOC101486339
uniprot id: A0A3P9C8U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101468165
gene id: 106582:LOC101468165
uniprot id: A0A3P9BJQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pla2g1b
gene id: 106582:pla2g1b
uniprot id: A0A3P9AS43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

106582:ccnj
gene id: 106582:ccnj
uniprot id: A0A3P9C255
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:LOC101486932
gene id: 106582:LOC101486932
uniprot id: A0A3P9CY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101464628
gene id: 106582:LOC101464628
uniprot id: A0A3P9CMM7
names: Subcellular Location Annotation
messages: Cytoplasm

106582:ercc1
gene id: 106582:ercc1
uniprot id: A0A3P9BSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

106582:ext2
gene id: 106582:ext2
uniprot id: A0A3P9AT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

106582:LOC101484346
gene id: 106582:LOC101484346
uniprot id: A0A3P9BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

106582:LOC101465619
gene id: 106582:LOC101465619
uniprot id: A0A3P9CQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

106582:LOC101483963
gene id: 106582:LOC101483963
uniprot id: A0A3P9CSF2
names: Similarity
messages: Belongs to the HEBP family.

106582:LOC101485405
gene id: 106582:LOC101485405
uniprot id: A0A3P9B404
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

106582:LOC101467984
gene id: 106582:LOC101467984
uniprot id: A0A3P9CDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

106582:LOC101482453
gene id: 106582:LOC101482453
uniprot id: A0A3P9C527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

106582:cdca5
gene id: 106582:cdca5
uniprot id: A0A3P9DM17
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

106582:foxp2
gene id: 106582:foxp2
uniprot id: V6F981
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101466674
gene id: 106582:LOC101466674
uniprot id: A0A3P9C4R0
names: Similarity
messages: Belongs to the syntaxin family.

106582:LOC101480450
gene id: 106582:LOC101480450
uniprot id: A0A3P9BT80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:slco2a1
gene id: 106582:slco2a1
uniprot id: A0A3P9BQV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101465152
gene id: 106582:LOC101465152
uniprot id: A0A3P9DJS6
names: Similarity
messages: Belongs to the BicD family.

106582:LOC101476566
gene id: 106582:LOC101476566
uniprot id: A0A3P9BNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

106582:LOC101469711
gene id: 106582:LOC101469711
uniprot id: A0A3P9AZD1
names: Subcellular Location Annotation
messages: Membrane

106582:eya4
gene id: 106582:eya4
uniprot id: A0A3P9CHC6
uniprot id: A0A3P9CHD6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

106582:LOC101486629
gene id: 106582:LOC101486629
uniprot id: A0A3P9DQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:mal2
gene id: 106582:mal2
uniprot id: A0A3P9DJ75
names: Subcellular Location Annotation
messages: Membrane

106582:osbpl11
gene id: 106582:osbpl11
uniprot id: A0A3P9CDR3
names: Similarity
messages: Belongs to the OSBP family.

106582:LOC101471337
gene id: 106582:LOC101471337
uniprot id: A0A3P9BAB4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101469576
gene id: 106582:LOC101469576
uniprot id: A0A3P9B2C5
names: Subcellular Location Annotation
messages: Z line

106582:LOC101472526
gene id: 106582:LOC101472526
uniprot id: A0A3P9B0L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

106582:LOC101477318
gene id: 106582:LOC101477318
uniprot id: A0A3P9AR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

106582:LOC101478924
gene id: 106582:LOC101478924
uniprot id: A0A3P9BMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

106582:LOC101481889
gene id: 106582:LOC101481889
uniprot id: A0A3P9CGC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101478978
gene id: 106582:LOC101478978
uniprot id: A0A3P9BB97
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

106582:ubr1
gene id: 106582:ubr1
uniprot id: A0A3P9BMV4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

106582:LOC101486642
gene id: 106582:LOC101486642
uniprot id: A0A3P9AWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

106582:opa3
gene id: 106582:opa3
uniprot id: A0A3P9DCT0
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

106582:LOC101467895
gene id: 106582:LOC101467895
uniprot id: A0A3P9AVK4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

106582:LOC101483700
gene id: 106582:LOC101483700
uniprot id: A0A3P9C8D1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473305
gene id: 106582:LOC101473305
uniprot id: A0A3P9DEK9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101471447
gene id: 106582:LOC101471447
uniprot id: A0A3P9BP74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

106582:LOC101480024
gene id: 106582:LOC101480024
uniprot id: A0A3P9BES5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

106582:LOC101472311
gene id: 106582:LOC101472311
uniprot id: A0A3P9DJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101471274
gene id: 106582:LOC101471274
uniprot id: A0A3P9D5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101482096
gene id: 106582:LOC101482096
uniprot id: A0A3P9B0X8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:pkig
gene id: 106582:pkig
uniprot id: A0A3P9D9Y7
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

106582:srp72
gene id: 106582:srp72
uniprot id: A0A3P9B384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

106582:LOC101470531
gene id: 106582:LOC101470531
uniprot id: A0A3P9ARD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:LOC101465901
gene id: 106582:LOC101465901
uniprot id: A0A3P9BA24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:st6gal2
gene id: 106582:st6gal2
uniprot id: A0A3P9D676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:brpf1
gene id: 106582:brpf1
uniprot id: A0A3P9DKA0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101485067
gene id: 106582:LOC101485067
uniprot id: A0A3P9DAU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: axon
messages: dendrite

106582:LOC101483562
gene id: 106582:LOC101483562
uniprot id: A0A3P9DUA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

106582:syf2
gene id: 106582:syf2
uniprot id: A0A3P9BEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

106582:LOC101475680
gene id: 106582:LOC101475680
uniprot id: A0A3P9BGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

106582:LOC101473231
gene id: 106582:LOC101473231
uniprot id: A0A3P9DSB6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

106582:naa38
gene id: 106582:naa38
uniprot id: A0A3P9D326
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

106582:trove2
gene id: 106582:trove2
uniprot id: A0A3P9BMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

106582:pfkfb2
gene id: 106582:pfkfb2
uniprot id: A0A3P9AWM2
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

106582:LOC101468636
gene id: 106582:LOC101468636
uniprot id: A0A3P9BYU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:epb41l5
gene id: 106582:epb41l5
uniprot id: A0A3P9AWK5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

106582:stac3
gene id: 106582:stac3
uniprot id: A0A3P9D069
names: Subcellular Location Annotation
messages: sarcolemma

106582:usp11
gene id: 106582:usp11
uniprot id: A0A3P9DMP9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101474439
gene id: 106582:LOC101474439
uniprot id: A0A3P9AT65
uniprot id: A0A3P9AU08
names: Similarity
messages: Belongs to the ubinuclein family.

106582:LOC101480409
gene id: 106582:LOC101480409
uniprot id: A0A3P9C831
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

106582:LOC101465878
gene id: 106582:LOC101465878
uniprot id: A0A3P9CN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

106582:LOC101481745
gene id: 106582:LOC101481745
uniprot id: A0A3P9BS89
names: Similarity
messages: Belongs to the pellino family.

106582:cops7a
gene id: 106582:cops7a
uniprot id: A0A3P9CR83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

106582:psmd2
gene id: 106582:psmd2
uniprot id: A0A3P9B3T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

106582:LOC101484745
gene id: 106582:LOC101484745
uniprot id: A0A3P9BRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

106582:plxna1
gene id: 106582:plxna1
uniprot id: A0A3P9DMT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101466194
gene id: 106582:LOC101466194
uniprot id: A0A3P9BAA8
uniprot id: A0A3P9BAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

106582:vps41
gene id: 106582:vps41
uniprot id: A0A3P9CQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

106582:slc19a1
gene id: 106582:slc19a1
uniprot id: A0A3P9D1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

106582:psmd12
gene id: 106582:psmd12
uniprot id: A0A3P9AYJ9
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

106582:yipf5
gene id: 106582:yipf5
uniprot id: A0A3P9B119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

106582:utp3
gene id: 106582:utp3
uniprot id: A0A3P9CAW1
names: Similarity
messages: Belongs to the SAS10 family.

106582:LOC101463905
gene id: 106582:LOC101463905
uniprot id: A0A3P9AUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

106582:cog7
gene id: 106582:cog7
uniprot id: A0A3P9C171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:p2ry8
gene id: 106582:p2ry8
uniprot id: A0A3P9D3J0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:sgce
gene id: 106582:sgce
uniprot id: A0A3P9BMG8
uniprot id: A0A3P9BNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: dendrite
messages: sarcolemma

106582:LOC101472417
gene id: 106582:LOC101472417
uniprot id: A0A3P9BSJ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

106582:tmem256
gene id: 106582:tmem256
uniprot id: A0A3P9BAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

106582:LOC101486854
gene id: 106582:LOC101486854
uniprot id: A0A3P9C9Q7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

106582:LOC101486881
gene id: 106582:LOC101486881
uniprot id: A0A3P9D6H9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

106582:LOC101482784
gene id: 106582:LOC101482784
uniprot id: A0A3P9CMD0
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

106582:nt5c3b
gene id: 106582:nt5c3b
uniprot id: A0A3P9D7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

106582:LOC101488005
gene id: 106582:LOC101488005
uniprot id: A0A3P9BQ75
uniprot id: A0A3P9BQ89
uniprot id: A0A3P9BR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

106582:atp5s
gene id: 106582:atp5s
uniprot id: A0A3P9C1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

106582:usp7
gene id: 106582:usp7
uniprot id: A0A3P9BKF6
names: Similarity
messages: Belongs to the peptidase C19 family.

106582:LOC101472718
gene id: 106582:LOC101472718
uniprot id: A0A3P9BAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

106582:LOC101465124
gene id: 106582:LOC101465124
uniprot id: A0A3P9C5A4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

106582:LOC101472547
gene id: 106582:LOC101472547
uniprot id: A0A3P9D6Z2
names: Similarity
messages: Belongs to the asteroid family.

106582:gbf1
gene id: 106582:gbf1
uniprot id: A0A3P9B4W1
names: Subcellular Location Annotation
messages: Golgi apparatus

106582:LOC101475864
gene id: 106582:LOC101475864
uniprot id: A0A3P9D973
names: Similarity
messages: Belongs to the FAM83 family.

106582:stag3
gene id: 106582:stag3
uniprot id: A0A3P9BRB7
uniprot id: A0A3P9BRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

106582:numb
gene id: 106582:numb
uniprot id: A0A3P9BY94
uniprot id: A0A3P9BYP5
uniprot id: A0A3P9BZA9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

106582:oaf
gene id: 106582:oaf
uniprot id: A0A3P9CG49
names: Similarity
messages: Belongs to the OAF family.

106582:abt1
gene id: 106582:abt1
uniprot id: A0A3P9DNV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

106582:LOC101487819
gene id: 106582:LOC101487819
uniprot id: A0A3P9CCD8
names: Subcellular Location Annotation
messages: Nucleus

106582:tmem214
gene id: 106582:tmem214
uniprot id: A0A3P9BAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101474234
gene id: 106582:LOC101474234
uniprot id: A0A3P9BPV8
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

106582:LOC101472077
gene id: 106582:LOC101472077
uniprot id: A0A3P9BPZ4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482562
gene id: 106582:LOC101482562
uniprot id: A0A3P9AS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

106582:LOC101467438
gene id: 106582:LOC101467438
uniprot id: A0A3P9BUX3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

106582:sox1
gene id: 106582:sox1
uniprot id: A0A3P9BM29
names: Subcellular Location Annotation
messages: Nucleus

106582:gtf2ird1
gene id: 106582:gtf2ird1
uniprot id: A0A3P9C001
uniprot id: A0A3P9C016
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101477957
gene id: 106582:LOC101477957
uniprot id: A0A3P9BFJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

106582:fgf7
gene id: 106582:fgf7
uniprot id: A0A3P9C1K9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:selenok
gene id: 106582:selenok
uniprot id: A0A3P9D0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

106582:LOC101484919
gene id: 106582:LOC101484919
uniprot id: A0A3P9C9N1
names: Similarity
messages: Belongs to the paralemmin family.

106582:prkd2
gene id: 106582:prkd2
uniprot id: A0A3P9CHD5
uniprot id: A0A3P9CIK2
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

106582:LOC101486557
gene id: 106582:LOC101486557
uniprot id: A0A3P9AQV3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

106582:sugp1
gene id: 106582:sugp1
uniprot id: A0A3P9DIJ8
names: Subcellular Location Annotation
messages: Nucleus

106582:fam160b1
gene id: 106582:fam160b1
uniprot id: A0A3P9BV65
names: Similarity
messages: Belongs to the FHIP family.

106582:LOC101463585
gene id: 106582:LOC101463585
uniprot id: A0A3P9CC85
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

106582:ndufb3
gene id: 106582:ndufb3
uniprot id: A0A3P9BYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

106582:LOC101473527
gene id: 106582:LOC101473527
uniprot id: A0A3P9D9P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

106582:pln
gene id: 106582:pln
uniprot id: A0A3P9BNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

106582:plk3
gene id: 106582:plk3
uniprot id: A0A3P9DIX5
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

106582:LOC101467062
gene id: 106582:LOC101467062
uniprot id: A0A3P9D250
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:slc52a3
gene id: 106582:slc52a3
uniprot id: A0A3P9DMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

106582:LOC101485300
gene id: 106582:LOC101485300
uniprot id: A0A3P9AZD9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:eif1ax
gene id: 106582:eif1ax
uniprot id: A0A3P9D0D5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

106582:LOC101470227
gene id: 106582:LOC101470227
uniprot id: A0A3P9CGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

106582:arl5b
gene id: 106582:arl5b
uniprot id: A0A3P9ATX0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:ppp1cc
gene id: 106582:ppp1cc
uniprot id: A0A3P9B0W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

106582:LOC101486899
gene id: 106582:LOC101486899
uniprot id: A0A3P9BA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

106582:ube2r2
gene id: 106582:ube2r2
uniprot id: A0A3P9DMI8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:gipc2
gene id: 106582:gipc2
uniprot id: A0A3P9DEP1
names: Similarity
messages: Belongs to the GIPC family.

106582:utp11
gene id: 106582:utp11
uniprot id: A0A3P9BME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

106582:LOC101473980
gene id: 106582:LOC101473980
uniprot id: A0A3P9AT39
names: Subcellular Location Annotation
messages: Cytoplasm

106582:lbx1
gene id: 106582:lbx1
uniprot id: A0A3P9BP93
names: Subcellular Location Annotation
messages: Nucleus

106582:hddc2
gene id: 106582:hddc2
uniprot id: A0A3P9C6N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

106582:usp20
gene id: 106582:usp20
uniprot id: A0A3P9B377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

106582:LOC101473447
gene id: 106582:LOC101473447
uniprot id: A0A3P9AVQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101484845
gene id: 106582:LOC101484845
uniprot id: A0A3P9D8U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

106582:rars
gene id: 106582:rars
uniprot id: A0A3P9C1F2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:trrap
gene id: 106582:trrap
uniprot id: A0A3P9BMG5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

106582:APK84 gp04
gene id: 106582:APK84_gp04
uniprot id: A0A0K2CJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

106582:papss1
gene id: 106582:papss1
uniprot id: A0A3P9CW63
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

106582:LOC101476200
gene id: 106582:LOC101476200
uniprot id: A0A3P9AZ33
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

106582:LOC101473691
gene id: 106582:LOC101473691
uniprot id: A0A3P9DC08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pou6f2
gene id: 106582:pou6f2
uniprot id: A0A3P9CRM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

106582:hnf4a
gene id: 106582:hnf4a
uniprot id: A0A3P9DAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:tmx2
gene id: 106582:tmx2
uniprot id: A0A3P9B1K3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

106582:slc12a8
gene id: 106582:slc12a8
uniprot id: A0A3P9BV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

106582:mrps15
gene id: 106582:mrps15
uniprot id: A0A3P9BHG3
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

106582:mcrip1
gene id: 106582:mcrip1
uniprot id: A0A3P9BNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

106582:LOC101468857
gene id: 106582:LOC101468857
uniprot id: A0A3P9AYT2
names: Similarity
messages: Belongs to the FAM131 family.

106582:lhx9
gene id: 106582:lhx9
uniprot id: A0A3P9CTH8
names: Subcellular Location Annotation
messages: Nucleus

106582:eno1
gene id: 106582:eno1
uniprot id: A0A3P9C602
uniprot id: A0A3P9C6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

106582:LOC101484092
gene id: 106582:LOC101484092
uniprot id: A0A3P9C4P3
names: Subcellular Location Annotation
messages: Membrane

106582:gle1
gene id: 106582:gle1
uniprot id: A0A3P9CZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

106582:ednra
gene id: 106582:ednra
uniprot id: A0A3P9BQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

106582:npffr2
gene id: 106582:npffr2
uniprot id: A0A3P9CZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

106582:LOC101479430
gene id: 106582:LOC101479430
uniprot id: A0A3P9CIZ1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101474937
gene id: 106582:LOC101474937
uniprot id: A0A3P9CV16
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:hpgd
gene id: 106582:hpgd
uniprot id: A0A3P9C889
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:elavl2
gene id: 106582:elavl2
uniprot id: A0A3P9AT85
names: Similarity
messages: Belongs to the RRM elav family.

106582:LOC101486321
gene id: 106582:LOC101486321
uniprot id: A0A3P9DN64
names: Similarity
messages: Belongs to the PPDPF family.

106582:LOC101466575
gene id: 106582:LOC101466575
uniprot id: A0A3P9CC93
uniprot id: A0A3P9CC96
uniprot id: A0A3P9CCB2
names: Subcellular Location Annotation
messages: Cytoplasm

106582:selenoo
gene id: 106582:selenoo
uniprot id: A0A3P9CKU1
names: Similarity
messages: Belongs to the SELO family.

106582:LOC101483408
gene id: 106582:LOC101483408
uniprot id: A0A3P9BZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:glyctk
gene id: 106582:glyctk
uniprot id: A0A3P9CB78
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

106582:LOC101483240
gene id: 106582:LOC101483240
uniprot id: A0A3P9BPN1
names: Subcellular Location Annotation
messages: Membrane

106582:homer3
gene id: 106582:homer3
uniprot id: A0A3P9CIZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

106582:LOC101476777
gene id: 106582:LOC101476777
uniprot id: A0A3P9AZQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

106582:ldb2
gene id: 106582:ldb2
uniprot id: A0A3P9AZ46
names: Similarity
messages: Belongs to the LDB family.

106582:LOC101477206
gene id: 106582:LOC101477206
uniprot id: A0A3P9C9Z6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:atf7
gene id: 106582:atf7
uniprot id: A0A3P9AX52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

106582:LOC101480766
gene id: 106582:LOC101480766
uniprot id: A0A3P9D792
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

106582:LOC101486794
gene id: 106582:LOC101486794
uniprot id: A0A3P9DQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

106582:LOC101476427
gene id: 106582:LOC101476427
uniprot id: A0A3P9DR33
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

106582:LOC101475100
gene id: 106582:LOC101475100
uniprot id: A0A3P9AWG9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:LOC101485540
gene id: 106582:LOC101485540
uniprot id: A0A3P9CB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

106582:LOC101487438
gene id: 106582:LOC101487438
uniprot id: A0A3P9B9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101478993
gene id: 106582:LOC101478993
uniprot id: A0A3P9CGJ5
names: Subcellular Location Annotation
messages: Nucleus

106582:tspan18
gene id: 106582:tspan18
uniprot id: A0A3P9BAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:tfap2d
gene id: 106582:tfap2d
uniprot id: A0A3P9B8F2
names: Similarity
messages: Belongs to the AP-2 family.

106582:mvd
gene id: 106582:mvd
uniprot id: A0A3P9C3P9
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

106582:sdhaf3
gene id: 106582:sdhaf3
uniprot id: A0A3P9CPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

106582:LOC101473149
gene id: 106582:LOC101473149
uniprot id: A0A3P9BQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

106582:LOC101474374
gene id: 106582:LOC101474374
uniprot id: A0A3P9CQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

106582:LOC101463828
gene id: 106582:LOC101463828
uniprot id: A0A3P9D680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

106582:LOC101470793
gene id: 106582:LOC101470793
uniprot id: A0A3P9BEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

106582:LOC101481659
gene id: 106582:LOC101481659
uniprot id: A0A3P9BKJ4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101482025
gene id: 106582:LOC101482025
uniprot id: A0A3P9CIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

106582:arl9
gene id: 106582:arl9
uniprot id: A0A3P9B3R4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:alg12
gene id: 106582:alg12
uniprot id: A0A3P9CED2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:gpd1
gene id: 106582:gpd1
uniprot id: A0A3P9B6B5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

106582:qtrt1
gene id: 106582:qtrt1
uniprot id: A0A3P9C840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

106582:smim19
gene id: 106582:smim19
uniprot id: A0A3P9BBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

106582:sec63
gene id: 106582:sec63
uniprot id: A0A3P9CEE1
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101475561
gene id: 106582:LOC101475561
uniprot id: A0A3P9D000
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:ndufb2
gene id: 106582:ndufb2
uniprot id: A0A3P9B1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

106582:fam149b1
gene id: 106582:fam149b1
uniprot id: A0A3P9DQR1
names: Similarity
messages: Belongs to the FAM149 family.

106582:setdb1
gene id: 106582:setdb1
uniprot id: A0A3P9CH22
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

106582:mrpl35
gene id: 106582:mrpl35
uniprot id: A0A3P9BL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

106582:lhx2
gene id: 106582:lhx2
uniprot id: A0A3P9CMT3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101487276
gene id: 106582:LOC101487276
uniprot id: A0A3P9CSJ0
uniprot id: A0A3P9CSJ5
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

106582:calhm6
gene id: 106582:calhm6
uniprot id: A0A3P9DHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

106582:LOC101487145
gene id: 106582:LOC101487145
uniprot id: A0A3P9B9C8
names: Subcellular Location Annotation
messages: Nucleus

106582:ndufb5
gene id: 106582:ndufb5
uniprot id: A0A3P9AYN2
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

106582:LOC101482873
gene id: 106582:LOC101482873
uniprot id: A0A3P9DP88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

106582:LOC101487422
gene id: 106582:LOC101487422
uniprot id: A0A3P9BQ97
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

106582:aars
gene id: 106582:aars
uniprot id: A0A3P9BW78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

106582:ilkap
gene id: 106582:ilkap
uniprot id: A0A3P9DF80
names: Similarity
messages: Belongs to the PP2C family.

106582:LOC101483211
gene id: 106582:LOC101483211
uniprot id: A0A3P9DFB9
names: Similarity
messages: Belongs to the NAD kinase family.

106582:LOC101471523
gene id: 106582:LOC101471523
uniprot id: A0A3P9BQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

106582:LOC101469868
gene id: 106582:LOC101469868
uniprot id: A0A3P9DCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:mettl11b
gene id: 106582:mettl11b
uniprot id: A0A3P9CN97
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

106582:LOC101482502
gene id: 106582:LOC101482502
uniprot id: A0A3P9BHJ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

106582:LOC101466221
gene id: 106582:LOC101466221
uniprot id: A0A3P9B2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:acvr1c
gene id: 106582:acvr1c
uniprot id: A0A3P9BNS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:LOC101475553
gene id: 106582:LOC101475553
uniprot id: A0A3P9CSW4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

106582:LOC101480235
gene id: 106582:LOC101480235
uniprot id: A0A3P9CEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

106582:hoxb8
gene id: 106582:hoxb8
uniprot id: A0A3P9D999
names: Subcellular Location Annotation
messages: Nucleus

106582:carnmt1
gene id: 106582:carnmt1
uniprot id: A0A3P9BVU2
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

106582:polr3d
gene id: 106582:polr3d
uniprot id: A0A3P9BZA8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101477139
gene id: 106582:LOC101477139
uniprot id: A0A3P9CH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

106582:LOC101474030
gene id: 106582:LOC101474030
uniprot id: A0A3P9ARY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

106582:atp2a3
gene id: 106582:atp2a3
uniprot id: A0A3P9D9H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

106582:LOC101472120
gene id: 106582:LOC101472120
uniprot id: A0A3P9AYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

106582:nampt
gene id: 106582:nampt
uniprot id: A0A3P9BWC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

106582:LOC101478668
gene id: 106582:LOC101478668
uniprot id: A0A3P9CW79
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC106676202
gene id: 106582:LOC106676202
uniprot id: A0A3P9BYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

106582:LOC101469344
gene id: 106582:LOC101469344
uniprot id: A0A3P9C6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:prrt1
gene id: 106582:prrt1
uniprot id: A0A3P9DLU0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:emc10
gene id: 106582:emc10
uniprot id: A0A3P9D8Y8
uniprot id: A0A3P9DAK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

106582:LOC101469391
gene id: 106582:LOC101469391
uniprot id: A0A3P9BKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:slc7a6os
gene id: 106582:slc7a6os
uniprot id: A0A3P9B5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

106582:dmap1
gene id: 106582:dmap1
uniprot id: A0A3P9B0A3
names: Subcellular Location Annotation
messages: Nucleus

106582:gla
gene id: 106582:gla
uniprot id: A0A3P9BP55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

106582:LOC101485854
gene id: 106582:LOC101485854
uniprot id: A0A3P9C9T1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101465250
gene id: 106582:LOC101465250
uniprot id: A0A3P9CLI2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:serinc4
gene id: 106582:serinc4
uniprot id: A0A3P9CFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

106582:nudt7
gene id: 106582:nudt7
uniprot id: A0A3P9CV41
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

106582:LOC101471142
gene id: 106582:LOC101471142
uniprot id: A0A3P9CDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:rps6ka3
gene id: 106582:rps6ka3
uniprot id: A0A3P9CZ84
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

106582:dlx5
gene id: 106582:dlx5
uniprot id: A0A3P9BQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

106582:ano10
gene id: 106582:ano10
uniprot id: A0A3P9DI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

106582:bsx
gene id: 106582:bsx
uniprot id: A0A3P9DC77
names: Subcellular Location Annotation
messages: Nucleus

106582:sfxn2
gene id: 106582:sfxn2
uniprot id: A0A3P9B5I2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

106582:LOC101474444
gene id: 106582:LOC101474444
uniprot id: A0A3P9CFZ1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101485383
gene id: 106582:LOC101485383
uniprot id: A0A3P9CMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101468684
gene id: 106582:LOC101468684
uniprot id: A0A3P9AZ61
names: Similarity
messages: Belongs to the TMEM178 family.

106582:LOC101464038
gene id: 106582:LOC101464038
uniprot id: A0A3P9C5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

106582:LOC101472156
gene id: 106582:LOC101472156
uniprot id: A0A3P9CUS3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

106582:iapp
gene id: 106582:iapp
uniprot id: A0A3P9CQE2
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

106582:gata6
gene id: 106582:gata6
uniprot id: A0A3P9DF17
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472165
gene id: 106582:LOC101472165
uniprot id: A0A3P9D5F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

106582:dkk3
gene id: 106582:dkk3
uniprot id: A0A3P9CBK2
names: Similarity
messages: Belongs to the dickkopf family.

106582:LOC101483143
gene id: 106582:LOC101483143
uniprot id: A0A3P9BY39
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

106582:LOC101470041
gene id: 106582:LOC101470041
uniprot id: A0A3P9DPE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

106582:LOC101478651
gene id: 106582:LOC101478651
uniprot id: A0A3P9DK80
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

106582:psme3
gene id: 106582:psme3
uniprot id: A0A3P9BII7
names: Similarity
messages: Belongs to the PA28 family.

106582:dll4
gene id: 106582:dll4
uniprot id: A0A3P9C631
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

106582:LOC101473612
gene id: 106582:LOC101473612
uniprot id: A0A3P9CRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

106582:LOC101482768
gene id: 106582:LOC101482768
uniprot id: A0A3P9CJA4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

106582:cdh11
gene id: 106582:cdh11
uniprot id: A0A3P9DR68
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:cenpx
gene id: 106582:cenpx
uniprot id: A0A3P9C5J7
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

106582:LOC101477634
gene id: 106582:LOC101477634
uniprot id: A0A3P9B3A7
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

106582:LOC101466093
gene id: 106582:LOC101466093
uniprot id: A0A3P9DIY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

106582:LOC101469308
gene id: 106582:LOC101469308
uniprot id: A0A3P9BJH0
names: Similarity
messages: Belongs to the serpin family.

106582:kpnb1
gene id: 106582:kpnb1
uniprot id: A0A3P9B7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

106582:LOC101471161
gene id: 106582:LOC101471161
uniprot id: A0A3P9DMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

106582:inpp5d
gene id: 106582:inpp5d
uniprot id: A0A3P9BNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

106582:dbr1
gene id: 106582:dbr1
uniprot id: A0A3P9D3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

106582:LOC101469881
gene id: 106582:LOC101469881
uniprot id: A0A3P9CE14
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:afmid
gene id: 106582:afmid
uniprot id: A0A3P9BLK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

106582:LOC101474141
gene id: 106582:LOC101474141
uniprot id: A0A3P9DG10
names: Similarity
messages: Belongs to the FMO family.

106582:mrpl3
gene id: 106582:mrpl3
uniprot id: A0A3P9BGA9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

106582:LOC101481490
gene id: 106582:LOC101481490
uniprot id: A0A3P9BVU1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:hgfac
gene id: 106582:hgfac
uniprot id: A0A3P9ARA8
uniprot id: A0A3P9ARB7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:wisp2
gene id: 106582:wisp2
uniprot id: A0A3P9DBL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101473737
gene id: 106582:LOC101473737
uniprot id: A0A3P9AVB8
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

106582:LOC101464687
gene id: 106582:LOC101464687
uniprot id: A0A3P9D354
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101469496
gene id: 106582:LOC101469496
uniprot id: A0A3P9CB12
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101485319
gene id: 106582:LOC101485319
uniprot id: A0A3P9DIM3
names: Subcellular Location Annotation
messages: Membrane

106582:vps11
gene id: 106582:vps11
uniprot id: A0A3P9DBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

106582:LOC101475153
gene id: 106582:LOC101475153
uniprot id: A0A3P9D591
names: Similarity
messages: Belongs to the globin family.

106582:pnpla4
gene id: 106582:pnpla4
uniprot id: A0A3P9CTW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:chpt1
gene id: 106582:chpt1
uniprot id: A0A3P9B486
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

106582:hoxc4
gene id: 106582:hoxc4
uniprot id: A0A3P9DQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:LOC106676068
gene id: 106582:LOC106676068
uniprot id: A0A3P9CJC1
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:LOC101464894
gene id: 106582:LOC101464894
uniprot id: A0A3P9DQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

106582:LOC101468101
gene id: 106582:LOC101468101
uniprot id: A0A3P9B1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

106582:LOC101484041
gene id: 106582:LOC101484041
uniprot id: A0A3P9DFA5
names: Similarity
messages: Belongs to the WD repeat coronin family.

106582:LOC101473015
gene id: 106582:LOC101473015
uniprot id: A0A3P9DKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

106582:LOC101474991
gene id: 106582:LOC101474991
uniprot id: A0A3P9BZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101468730
gene id: 106582:LOC101468730
uniprot id: A0A3P9B4I7
names: Similarity
messages: Belongs to the heme oxygenase family.

106582:ndst1
gene id: 106582:ndst1
uniprot id: A0A3P9C5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

106582:LOC101477913
gene id: 106582:LOC101477913
uniprot id: A0A3P9DKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

106582:wls
gene id: 106582:wls
uniprot id: A0A3P9B6Z8
uniprot id: A0A3P9B738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

106582:gar1
gene id: 106582:gar1
uniprot id: A0A3P9AV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

106582:LOC101481641
gene id: 106582:LOC101481641
uniprot id: A0A3P9DQN1
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

106582:cmtm7
gene id: 106582:cmtm7
uniprot id: A0A3P9CL60
names: Subcellular Location Annotation
messages: Membrane

106582:gpc2
gene id: 106582:gpc2
uniprot id: A0A3P9BRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

106582:LOC101477372
gene id: 106582:LOC101477372
uniprot id: A0A3P9C8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

106582:npm3
gene id: 106582:npm3
uniprot id: A0A3P9B257
names: Similarity
messages: Belongs to the nucleoplasmin family.

106582:cstf3
gene id: 106582:cstf3
uniprot id: A0A3P9C1I7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101474679
gene id: 106582:LOC101474679
uniprot id: A0A3P9D4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101481992
gene id: 106582:LOC101481992
uniprot id: A0A3P9C4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

106582:myo10
gene id: 106582:myo10
uniprot id: A0A3P9ART4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:rnft1
gene id: 106582:rnft1
uniprot id: A0A3P9DB18
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101466857
gene id: 106582:LOC101466857
uniprot id: A0A3P9C2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

106582:rpl34
gene id: 106582:rpl34
uniprot id: A0A3P9AY11
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

106582:nos1
gene id: 106582:nos1
uniprot id: A0A3P9CX80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

106582:LOC101470480
gene id: 106582:LOC101470480
uniprot id: A0A3P9ARK7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101463955
gene id: 106582:LOC101463955
uniprot id: A0A3P9C5Z4
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

106582:ssr3
gene id: 106582:ssr3
uniprot id: A0A3P9BXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

106582:LOC101476542
gene id: 106582:LOC101476542
uniprot id: A0A3P9CXM1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101472552
gene id: 106582:LOC101472552
uniprot id: A0A3P9BNI4
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

106582:LOC101478455
gene id: 106582:LOC101478455
uniprot id: A0A3P9CQC6
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

106582:LOC101470907
gene id: 106582:LOC101470907
uniprot id: A0A3P9B662
names: Similarity
messages: Belongs to the CRK family.

106582:dhcr7
gene id: 106582:dhcr7
uniprot id: A0A3P9AQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

106582:zc3h12d
gene id: 106582:zc3h12d
uniprot id: A0A3P9CFT5
names: Similarity
messages: Belongs to the ZC3H12 family.

106582:lpar1
gene id: 106582:lpar1
uniprot id: A0A3P9CIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

106582:elovl7
gene id: 106582:elovl7
uniprot id: A0A3P9BDI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101464737
gene id: 106582:LOC101464737
uniprot id: A0A3P9AXZ7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101488099
gene id: 106582:LOC101488099
uniprot id: A0A3P9AV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:LOC101484472
gene id: 106582:LOC101484472
uniprot id: A0A3P9CU25
names: Subcellular Location Annotation
messages: Membrane

106582:dse
gene id: 106582:dse
uniprot id: A0A3P9CFX1
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

106582:nup50
gene id: 106582:nup50
uniprot id: A0A3P9CTG5
names: Subcellular Location Annotation
messages: nuclear pore complex

106582:lg3h4orf48
gene id: 106582:lg3h4orf48
uniprot id: A0A3P9D0N8
names: Subcellular Location Annotation
messages: Secreted

106582:zcchc8
gene id: 106582:zcchc8
uniprot id: A0A3P9AV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

106582:LOC101479776
gene id: 106582:LOC101479776
uniprot id: A0A3P9CK17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

106582:mttp
gene id: 106582:mttp
uniprot id: A0A3P9D894
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:fam136a
gene id: 106582:fam136a
uniprot id: A0A3P9CPF4
names: Similarity
messages: Belongs to the FAM136 family.

106582:LOC101468626
gene id: 106582:LOC101468626
uniprot id: A0A3P9CMK8
names: Similarity
messages: Belongs to the SLBP family.

106582:LOC101471824
gene id: 106582:LOC101471824
uniprot id: A0A3P9BEY6
names: Subcellular Location Annotation
messages: Nucleus

106582:pcnx1
gene id: 106582:pcnx1
uniprot id: A0A3P9BX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

106582:LOC101485095
gene id: 106582:LOC101485095
uniprot id: A0A3P9B4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101477205
gene id: 106582:LOC101477205
uniprot id: A0A3P9BYS4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

106582:ildr1
gene id: 106582:ildr1
uniprot id: A0A3P9D4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

106582:LOC101463598
gene id: 106582:LOC101463598
uniprot id: A0A3P9D3K5
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

106582:stk32c
gene id: 106582:stk32c
uniprot id: A0A3P9CPX9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101486086
gene id: 106582:LOC101486086
uniprot id: A0A3P9C918
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:wdr83os
gene id: 106582:wdr83os
uniprot id: A0A3P9CBB1
names: Similarity
messages: Belongs to the Asterix family.

106582:eed
gene id: 106582:eed
uniprot id: A0A3P9CEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

106582:uvssa
gene id: 106582:uvssa
uniprot id: A0A3P9CN75
names: Similarity
messages: Belongs to the UVSSA family.

106582:LOC101470828
gene id: 106582:LOC101470828
uniprot id: A0A3P9BJU5
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

106582:clvs2
gene id: 106582:clvs2
uniprot id: A0A3P9BES9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

106582:LOC101465325
gene id: 106582:LOC101465325
uniprot id: A0A3P9CJG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

106582:LOC101471787
gene id: 106582:LOC101471787
uniprot id: A0A3P9B9J1
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:snx6
gene id: 106582:snx6
uniprot id: A0A3P9CMG8
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

106582:osbpl9
gene id: 106582:osbpl9
uniprot id: A0A3P9B6L4
uniprot id: A0A3P9B6U0
names: Similarity
messages: Belongs to the OSBP family.

106582:slc35b4
gene id: 106582:slc35b4
uniprot id: A0A3P9BHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

106582:zdhhc24
gene id: 106582:zdhhc24
uniprot id: A0A3P9B609
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101477758
gene id: 106582:LOC101477758
uniprot id: A0A3P9DCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

106582:rps6ka5
gene id: 106582:rps6ka5
uniprot id: A0A3P9CDH0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

106582:parvb
gene id: 106582:parvb
uniprot id: A0A3P9BQB9
uniprot id: A0A3P9BR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

106582:LOC101484368
gene id: 106582:LOC101484368
uniprot id: A0A3P9CYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:ndor1
gene id: 106582:ndor1
uniprot id: A0A3P9ATZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

106582:LOC101470393
gene id: 106582:LOC101470393
uniprot id: A0A3P9C3I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

106582:LOC101477172
gene id: 106582:LOC101477172
uniprot id: A0A3P9BHI8
names: Similarity
messages: Belongs to the ZC3H12 family.

106582:LOC101468438
gene id: 106582:LOC101468438
uniprot id: A0A3P9C062
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101473685
gene id: 106582:LOC101473685
uniprot id: A0A3P9AWK0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

106582:LOC101480328
gene id: 106582:LOC101480328
uniprot id: A0A3P9BC42
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:afap1l1
gene id: 106582:afap1l1
uniprot id: A0A3P9BM10
uniprot id: A0A3P9BM19
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

106582:uroc1
gene id: 106582:uroc1
uniprot id: A0A3P9BS28
names: Similarity
messages: Belongs to the urocanase family.

106582:LOC101485275
gene id: 106582:LOC101485275
uniprot id: A0A3P9C8F0
names: Subcellular Location Annotation
messages: Membrane

106582:tmem107
gene id: 106582:tmem107
uniprot id: A0A3P9CE98
names: Subcellular Location Annotation
messages: Membrane

106582:tmem106b
gene id: 106582:tmem106b
uniprot id: A0A3P9CEF0
names: Similarity
messages: Belongs to the TMEM106 family.

106582:haus1
gene id: 106582:haus1
uniprot id: A0A3P9DDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

106582:LOC101476456
gene id: 106582:LOC101476456
uniprot id: A0A3P9C7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:LOC101480582
gene id: 106582:LOC101480582
uniprot id: A0A3P9D9S2
uniprot id: A0A3P9D9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

106582:LOC101486588
gene id: 106582:LOC101486588
uniprot id: F8TJW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

106582:LOC101482920
gene id: 106582:LOC101482920
uniprot id: A0A3P9B2B1
names: Similarity
messages: Belongs to the centrin family.

106582:ppt2
gene id: 106582:ppt2
uniprot id: A0A3P9DMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

106582:ccdc167
gene id: 106582:ccdc167
uniprot id: A0A3P9CN68
names: Subcellular Location Annotation
messages: Membrane

106582:mst1
gene id: 106582:mst1
uniprot id: A0A3P9CDB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:LOC101474597
gene id: 106582:LOC101474597
uniprot id: A0A3P9C8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

106582:coro2b
gene id: 106582:coro2b
uniprot id: A0A3P9C5W5
uniprot id: A0A3P9C6H2
names: Similarity
messages: Belongs to the WD repeat coronin family.

106582:pfdn5
gene id: 106582:pfdn5
uniprot id: A0A3P9BK63
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

106582:oxct1
gene id: 106582:oxct1
uniprot id: A0A3P9BGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

106582:LOC101476562
gene id: 106582:LOC101476562
uniprot id: A0A3P9B187
names: Similarity
messages: Belongs to the NSG family.

106582:capn9
gene id: 106582:capn9
uniprot id: A0A3P9BAN0
names: Similarity
messages: Belongs to the peptidase C2 family.

106582:homer2
gene id: 106582:homer2
uniprot id: A0A3P9BFL0
uniprot id: A0A3P9BFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Postsynaptic density
messages: Synapse

106582:LOC101477664
gene id: 106582:LOC101477664
uniprot id: A0A3P9CT02
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

106582:LOC101466772
gene id: 106582:LOC101466772
uniprot id: A0A3P9DID7
uniprot id: A0A3P9DJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

106582:LOC101472869
gene id: 106582:LOC101472869
uniprot id: A0A3P9BSE5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106582:LOC101470019
gene id: 106582:LOC101470019
uniprot id: A0A3P9CWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

106582:taf2
gene id: 106582:taf2
uniprot id: A0A3P9DG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

106582:rplp1
gene id: 106582:rplp1
uniprot id: A0A3P9DNI5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

106582:LOC101487089
gene id: 106582:LOC101487089
uniprot id: A0A3P9B5Y8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:ncoa3
gene id: 106582:ncoa3
uniprot id: A0A3P9DKA6
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

106582:enpp4
gene id: 106582:enpp4
uniprot id: A0A3P9B3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

106582:LOC101466282
gene id: 106582:LOC101466282
uniprot id: A0A3P9BIE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:cacng1
gene id: 106582:cacng1
uniprot id: A0A3P9AXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

106582:LOC101475003
gene id: 106582:LOC101475003
uniprot id: A0A3P9AT89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

106582:LOC101487800
gene id: 106582:LOC101487800
uniprot id: A0A3P9CM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:ndufb7
gene id: 106582:ndufb7
uniprot id: A0A3P9B7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

106582:slain1
gene id: 106582:slain1
uniprot id: A0A3P9D4B6
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

106582:kcnq2
gene id: 106582:kcnq2
uniprot id: A0A3P9BNT4
uniprot id: A0A3P9BNW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101464381
gene id: 106582:LOC101464381
uniprot id: A0A3P9D8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:LOC101488064
gene id: 106582:LOC101488064
uniprot id: A0A3P9C2V2
names: Subcellular Location Annotation
messages: Nucleus

106582:acox3
gene id: 106582:acox3
uniprot id: A0A3P9BRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

106582:LOC101471140
gene id: 106582:LOC101471140
uniprot id: A0A3P9B3T6
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

106582:LOC101467714
gene id: 106582:LOC101467714
uniprot id: A0A3P9AYE4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:efhc2
gene id: 106582:efhc2
uniprot id: A0A3P9CZR8
names: Subcellular Location Annotation
messages: cilium axoneme

106582:ing3
gene id: 106582:ing3
uniprot id: A0A3P9CQV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

106582:LOC101487257
gene id: 106582:LOC101487257
uniprot id: A0A3P9BD48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:isca1
gene id: 106582:isca1
uniprot id: A0A3P9C4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

106582:LOC101486224
gene id: 106582:LOC101486224
uniprot id: A0A3P9DE28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

106582:LOC101477642
gene id: 106582:LOC101477642
uniprot id: A0A3P9DHR3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:epha4
gene id: 106582:epha4
uniprot id: A0A3P9B893
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

106582:LOC101482949
gene id: 106582:LOC101482949
uniprot id: A0A3P9C4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:pcbd2
gene id: 106582:pcbd2
uniprot id: A0A3P9BQQ9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106582:LOC101478451
gene id: 106582:LOC101478451
uniprot id: A0A3P9BZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

106582:sec31a
gene id: 106582:sec31a
uniprot id: A0A3P9BIU1
uniprot id: A0A3P9BIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

106582:snx5
gene id: 106582:snx5
uniprot id: A0A3P9BPI6
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

106582:LOC101466447
gene id: 106582:LOC101466447
uniprot id: A0A3P9CVC5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

106582:msl3
gene id: 106582:msl3
uniprot id: A0A3P9B8Y2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101464615
gene id: 106582:LOC101464615
uniprot id: A0A3P9D3B7
names: Similarity
messages: Belongs to the OSBP family.

106582:LOC101483159
gene id: 106582:LOC101483159
uniprot id: A0A3P9DLB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

106582:rabggtb
gene id: 106582:rabggtb
uniprot id: A0A3P9DEL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

106582:tspan6
gene id: 106582:tspan6
uniprot id: A0A3P9BIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:dgke
gene id: 106582:dgke
uniprot id: A0A3P9C050
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

106582:LOC101475882
gene id: 106582:LOC101475882
uniprot id: A0A3P9D1M7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

106582:LOC101484891
gene id: 106582:LOC101484891
uniprot id: A0A3P9C2W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:evc
gene id: 106582:evc
uniprot id: A0A3P9DP91
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

106582:LOC101478135
gene id: 106582:LOC101478135
uniprot id: A0A3P9BXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

106582:rps19bp1
gene id: 106582:rps19bp1
uniprot id: A0A3P9BDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

106582:fnta
gene id: 106582:fnta
uniprot id: A0A3P9BD23
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

106582:tada2a
gene id: 106582:tada2a
uniprot id: A0A3P9BLS0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482997
gene id: 106582:LOC101482997
uniprot id: A0A3P9CUZ3
uniprot id: A0A3P9CWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

106582:LOC101480447
gene id: 106582:LOC101480447
uniprot id: A0A3P9BNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:taf8
gene id: 106582:taf8
uniprot id: A0A3P9DA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

106582:glmp
gene id: 106582:glmp
uniprot id: A0A3P9C1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

106582:LOC101474979
gene id: 106582:LOC101474979
uniprot id: A0A3P9BIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

106582:LOC101472107
gene id: 106582:LOC101472107
uniprot id: A0A3P9D1Q1
names: Similarity
messages: Belongs to the GroES chaperonin family.

106582:efnb1
gene id: 106582:efnb1
uniprot id: A0A3P9BIN1
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:sppl2b
gene id: 106582:sppl2b
uniprot id: A0A3P9DDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

106582:LOC101466449
gene id: 106582:LOC101466449
uniprot id: A0A3P9B8F0
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

106582:LOC101487244
gene id: 106582:LOC101487244
uniprot id: A0A3P9C3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

106582:eipr1
gene id: 106582:eipr1
uniprot id: A0A3P9B6U1
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

106582:sh3bgrl2
gene id: 106582:sh3bgrl2
uniprot id: A0A3P9CHU7
names: Similarity
messages: Belongs to the SH3BGR family.

106582:LOC101481171
gene id: 106582:LOC101481171
uniprot id: A0A3P9DMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

106582:LOC101475651
gene id: 106582:LOC101475651
uniprot id: A0A3P9DRV4
names: Similarity
messages: Belongs to the peptidase C64 family.

106582:fgd1
gene id: 106582:fgd1
uniprot id: A0A3P9DNQ1
uniprot id: A0A3P9DNY2
names: Subcellular Location Annotation
messages: cytoskeleton

106582:nkx6-2
gene id: 106582:nkx6-2
uniprot id: A0A3P9CP04
names: Subcellular Location Annotation
messages: Nucleus

106582:zdhhc16
gene id: 106582:zdhhc16
uniprot id: A0A3P9B2H0
uniprot id: A0A3P9B2X1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:lg15h19orf24
gene id: 106582:lg15h19orf24
uniprot id: A0A3P9B2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

106582:LOC101805558
gene id: 106582:LOC101805558
uniprot id: A0A3P9DBA4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:yif1a
gene id: 106582:yif1a
uniprot id: A0A3P9BAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

106582:med10
gene id: 106582:med10
uniprot id: A0A3P9AR12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:LOC101483831
gene id: 106582:LOC101483831
uniprot id: A0A3P9DE33
names: Similarity
messages: Belongs to the peptidase M10A family.

106582:nubpl
gene id: 106582:nubpl
uniprot id: A0A3P9AV00
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

106582:APK84 gp08
gene id: 106582:APK84_gp08
uniprot id: A0A0K2CJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

106582:stam2
gene id: 106582:stam2
uniprot id: A0A3P9CTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

106582:LOC101478796
gene id: 106582:LOC101478796
uniprot id: A0A3P9BYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

106582:LOC101473818
gene id: 106582:LOC101473818
uniprot id: A0A3P9CC28
names: Similarity
messages: Belongs to the UPF0046 family.

106582:ezh1
gene id: 106582:ezh1
uniprot id: A0A3P9D8F4
names: Subcellular Location Annotation
messages: Nucleus

106582:lactb2
gene id: 106582:lactb2
uniprot id: A0A3P9B6Z0
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

106582:LOC101481473
gene id: 106582:LOC101481473
uniprot id: A0A3P9C0Q5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

106582:sar1b
gene id: 106582:sar1b
uniprot id: A0A3P9BPR0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

106582:LOC101484886
gene id: 106582:LOC101484886
uniprot id: A0A3P9ASL4
names: Subcellular Location Annotation
messages: Nucleus

106582:ighmbp2
gene id: 106582:ighmbp2
uniprot id: A0A3P9ATK0
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

106582:LOC101480126
gene id: 106582:LOC101480126
uniprot id: A0A3P9BNB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101481191
gene id: 106582:LOC101481191
uniprot id: A0A3P9DC34
uniprot id: A0A3P9DD68
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

106582:fmr1
gene id: 106582:fmr1
uniprot id: A0A3P9BBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

106582:LOC101465512
gene id: 106582:LOC101465512
uniprot id: A0A3P9CDM9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

106582:ppm1k
gene id: 106582:ppm1k
uniprot id: A0A3P9CV25
names: Similarity
messages: Belongs to the PP2C family.

106582:slc30a9
gene id: 106582:slc30a9
uniprot id: A0A3P9BQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

106582:LOC101465360
gene id: 106582:LOC101465360
uniprot id: A0A3P9AWX4
names: Similarity
messages: Belongs to the TMEM121 family.

106582:nrf1
gene id: 106582:nrf1
uniprot id: A0A3P9BHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

106582:rbks
gene id: 106582:rbks
uniprot id: A0A3P9BSM0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

106582:rpl37
gene id: 106582:rpl37
uniprot id: A0A3P9AY75
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

106582:ccdc47
gene id: 106582:ccdc47
uniprot id: A0A3P9D8J6
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

106582:clrn1
gene id: 106582:clrn1
uniprot id: A0A3P9AZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

106582:LOC101479139
gene id: 106582:LOC101479139
uniprot id: A0A3P9AU90
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

106582:pou3f1
gene id: 106582:pou3f1
uniprot id: A0A3P9BMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

106582:LOC101477094
gene id: 106582:LOC101477094
uniprot id: A0A3P9CV92
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:brinp1
gene id: 106582:brinp1
uniprot id: A0A3P9CW40
names: Similarity
messages: Belongs to the BRINP family.

106582:LOC101479683
gene id: 106582:LOC101479683
uniprot id: A0A3P9CHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:wnt11
gene id: 106582:wnt11
uniprot id: A0A3P9D8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

106582:LOC101476188
gene id: 106582:LOC101476188
uniprot id: A0A3P9BML7
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101475091
gene id: 106582:LOC101475091
uniprot id: A0A3P9AXK7
names: Similarity
messages: Belongs to the MARCKS family.

106582:cisd2
gene id: 106582:cisd2
uniprot id: A0A3P9DBX6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

106582:ube2i
gene id: 106582:ube2i
uniprot id: A0A3P9BZ25
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101465438
gene id: 106582:LOC101465438
uniprot id: A0A3P9D679
names: Subcellular Location Annotation
messages: Nucleus

106582:cdc123
gene id: 106582:cdc123
uniprot id: A0A3P9CDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

106582:LOC101475339
gene id: 106582:LOC101475339
uniprot id: A0A3P9BIW8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

106582:LOC101476753
gene id: 106582:LOC101476753
uniprot id: A0A3P9BSE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101463575
gene id: 106582:LOC101463575
uniprot id: A0A3P9DAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

106582:LOC101487687
gene id: 106582:LOC101487687
uniprot id: A0A3P9CBL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101480072
gene id: 106582:LOC101480072
uniprot id: A0A3P9CMV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:mcm10
gene id: 106582:mcm10
uniprot id: A0A3P9CDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

106582:mus81
gene id: 106582:mus81
uniprot id: A0A3P9CW08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

106582:LOC101485833
gene id: 106582:LOC101485833
uniprot id: A0A3P9BP94
names: Subcellular Location Annotation
messages: Mitochondrion

106582:slc2a2
gene id: 106582:slc2a2
uniprot id: A0A3P9C9L1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:LOC101476370
gene id: 106582:LOC101476370
uniprot id: A0A3P9DG00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

106582:LOC101483965
gene id: 106582:LOC101483965
uniprot id: A0A3P9BIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101478637
gene id: 106582:LOC101478637
uniprot id: A0A3P9B8A8
names: Similarity
messages: Belongs to the pyruvate kinase family.

106582:gna12
gene id: 106582:gna12
uniprot id: A0A3P9C141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

106582:vegfa
gene id: 106582:vegfa
uniprot id: A0A3P9CCA2
uniprot id: A0A3P9CCA7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

106582:bcap29
gene id: 106582:bcap29
uniprot id: A0A3P9CCJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

106582:LOC101479424
gene id: 106582:LOC101479424
uniprot id: A0A3P9DHZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106582:yod1
gene id: 106582:yod1
uniprot id: A0A3P9AX33
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

106582:pmpcb
gene id: 106582:pmpcb
uniprot id: A0A3P9BK38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

106582:LOC101475152
gene id: 106582:LOC101475152
uniprot id: A0A3P9CBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:tnfsf12
gene id: 106582:tnfsf12
uniprot id: A0A3P9D2W3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:sox8
gene id: 106582:sox8
uniprot id: A0A3P9C550
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101485743
gene id: 106582:LOC101485743
uniprot id: A0A3P9B165
names: Subcellular Location Annotation
messages: Nucleus

106582:pex13
gene id: 106582:pex13
uniprot id: A0A3P9CQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

106582:tbcc
gene id: 106582:tbcc
uniprot id: A0A3P9B8H8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

106582:ndufa1
gene id: 106582:ndufa1
uniprot id: A0A3P9BKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

106582:LOC101483592
gene id: 106582:LOC101483592
uniprot id: A0A3P9BE68
names: Similarity
messages: Belongs to the DeSI family.

106582:LOC101474918
gene id: 106582:LOC101474918
uniprot id: A0A3P9BX85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

106582:med31
gene id: 106582:med31
uniprot id: A0A3P9DGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

106582:paqr3
gene id: 106582:paqr3
uniprot id: A0A3P9CZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

106582:ssr4
gene id: 106582:ssr4
uniprot id: A0A3P9DPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

106582:sar1a
gene id: 106582:sar1a
uniprot id: A0A3P9ATZ9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

106582:lrrn1
gene id: 106582:lrrn1
uniprot id: A0A3P9BQM8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101487635
gene id: 106582:LOC101487635
uniprot id: A0A3P9CN85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

106582:LOC101472722
gene id: 106582:LOC101472722
uniprot id: A0A3P9BD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

106582:rpl5
gene id: 106582:rpl5
uniprot id: A0A3P9BTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

106582:dcps
gene id: 106582:dcps
uniprot id: A0A3P9BBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

106582:LOC101473002
gene id: 106582:LOC101473002
uniprot id: A0A3P9DN34
names: Subcellular Location Annotation
messages: Membrane

106582:ubac1
gene id: 106582:ubac1
uniprot id: A0A3P9C9P7
names: Subcellular Location Annotation
messages: Cytoplasm

106582:cog1
gene id: 106582:cog1
uniprot id: A0A3P9D8B7
names: Similarity
messages: Belongs to the COG1 family.

106582:LOC101476649
gene id: 106582:LOC101476649
uniprot id: A0A3P9BLJ9
names: Similarity
messages: Belongs to the TOM1 family.

106582:nme5
gene id: 106582:nme5
uniprot id: A0A3P9C455
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

106582:chst1
gene id: 106582:chst1
uniprot id: A0A3P9CA45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:LOC101473433
gene id: 106582:LOC101473433
uniprot id: A0A3P9BAM2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

106582:tbc1d24
gene id: 106582:tbc1d24
uniprot id: A0A3P9C0K5
names: Subcellular Location Annotation
messages: Membrane

106582:cnn1
gene id: 106582:cnn1
uniprot id: A0A3P9AXS5
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

106582:LOC101468472
gene id: 106582:LOC101468472
uniprot id: A0A3P9DMX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

106582:mpv17
gene id: 106582:mpv17
uniprot id: A0A3P9BEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

106582:LOC101474513
gene id: 106582:LOC101474513
uniprot id: A0A3P9CJD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

106582:LOC101478571
gene id: 106582:LOC101478571
uniprot id: A0A3P9C0Q8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101469008
gene id: 106582:LOC101469008
uniprot id: A0A3P9CGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

106582:csk
gene id: 106582:csk
uniprot id: A0A3P9BBZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:LOC101478426
gene id: 106582:LOC101478426
uniprot id: A0A3P9BUA1
names: Cofactor
messages: Binds 2 iron ions per subunit.

106582:park7
gene id: 106582:park7
uniprot id: A0A3P9C9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

106582:LOC101477057
gene id: 106582:LOC101477057
uniprot id: A0A3P9CL06
uniprot id: A0A3P9CMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

106582:eftud2
gene id: 106582:eftud2
uniprot id: A0A3P9D7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

106582:LOC101484979
gene id: 106582:LOC101484979
uniprot id: A0A3P9AVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

106582:LOC101487767
gene id: 106582:LOC101487767
uniprot id: A0A3P9AT63
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

106582:LOC101478716
gene id: 106582:LOC101478716
uniprot id: A0A3P9B564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

106582:LOC101474602
gene id: 106582:LOC101474602
uniprot id: A0A3P9C8V0
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:oprl1
gene id: 106582:oprl1
uniprot id: A0A3P9DNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

106582:cdc26
gene id: 106582:cdc26
uniprot id: A0A3P9DAJ4
names: Similarity
messages: Belongs to the CDC26 family.

106582:LOC101485614
gene id: 106582:LOC101485614
uniprot id: A0A3P9B8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101469628
gene id: 106582:LOC101469628
uniprot id: A0A3P9B0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:LOC101475329
gene id: 106582:LOC101475329
uniprot id: A0A3P9CFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

106582:hepacam2
gene id: 106582:hepacam2
uniprot id: A0A3P9BLH8
names: Subcellular Location Annotation
messages: Membrane

106582:eif5
gene id: 106582:eif5
uniprot id: A0A3P9AYD0
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

106582:avl9
gene id: 106582:avl9
uniprot id: A0A3P9CV00
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

106582:dpm3
gene id: 106582:dpm3
uniprot id: A0A3P9DL98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

106582:nov
gene id: 106582:nov
uniprot id: A0A3P9DIM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:tecr
gene id: 106582:tecr
uniprot id: A0A3P9B7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101476376
gene id: 106582:LOC101476376
uniprot id: A0A3P9CJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:ptk7
gene id: 106582:ptk7
uniprot id: A0A3P9BV41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:pin4
gene id: 106582:pin4
uniprot id: A0A3P9BQ21
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

106582:LOC101486556
gene id: 106582:LOC101486556
uniprot id: A0A3P9CI97
uniprot id: A0A3P9CIR9
uniprot id: A0A3P9CIX1
uniprot id: A0A3P9CJ46
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:LOC101471269
gene id: 106582:LOC101471269
uniprot id: A0A3P9AZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

106582:sptlc2
gene id: 106582:sptlc2
uniprot id: A0A3P9BF16
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

106582:faah2
gene id: 106582:faah2
uniprot id: A0A3P9D0G9
names: Similarity
messages: Belongs to the amidase family.

106582:LOC101472534
gene id: 106582:LOC101472534
uniprot id: A0A3P9DM32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

106582:mad1l1
gene id: 106582:mad1l1
uniprot id: A0A3P9C7G9
names: Similarity
messages: Belongs to the MAD1 family.

106582:LOC101487004
gene id: 106582:LOC101487004
uniprot id: A0A3P9CMR2
names: Similarity
messages: Belongs to the MS4A family.

106582:LOC101483528
gene id: 106582:LOC101483528
uniprot id: A0A3P9DEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

106582:slc2a11
gene id: 106582:slc2a11
uniprot id: A0A3P9CGD4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:LOC101469781
gene id: 106582:LOC101469781
uniprot id: A0A3P9BZW4
names: Similarity
messages: Belongs to the SH3RF family.

106582:tcta
gene id: 106582:tcta
uniprot id: A0A3P9CCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

106582:cxcr5
gene id: 106582:cxcr5
uniprot id: A0A3P9DDY4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101469209
gene id: 106582:LOC101469209
uniprot id: A0A3P9CU43
names: Subcellular Location Annotation
messages: ruffle membrane

106582:LOC101479798
gene id: 106582:LOC101479798
uniprot id: A0A3P9CAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

106582:LOC101484908
gene id: 106582:LOC101484908
uniprot id: A0A3P9BYU0
names: Subcellular Location Annotation
messages: Cytoplasm

106582:glrx
gene id: 106582:glrx
uniprot id: A0A3P9DPD5
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

106582:LOC101474199
gene id: 106582:LOC101474199
uniprot id: A0A3P9DMB0
names: Similarity
messages: Belongs to the S-100 family.

106582:LOC101476363
gene id: 106582:LOC101476363
uniprot id: A0A3P9C4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

106582:ankrd13a
gene id: 106582:ankrd13a
uniprot id: A0A3P9CHH8
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

106582:dennd5a
gene id: 106582:dennd5a
uniprot id: A0A3P9CCW9
uniprot id: A0A3P9CDE8
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:gnptab
gene id: 106582:gnptab
uniprot id: A0A3P9B4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

106582:pdha1
gene id: 106582:pdha1
uniprot id: A0A3P9CZA4
uniprot id: A0A3P9D0J3
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

106582:LOC101468121
gene id: 106582:LOC101468121
uniprot id: A0A3P9BJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:paf1
gene id: 106582:paf1
uniprot id: A0A3P9BIH6
names: Similarity
messages: Belongs to the PAF1 family.

106582:atp5pb
gene id: 106582:atp5pb
uniprot id: A0A3P9BHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

106582:LOC101483360
gene id: 106582:LOC101483360
uniprot id: A0A3P9B414
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

106582:arl1
gene id: 106582:arl1
uniprot id: A0A3P9CQA9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:LOC101488128
gene id: 106582:LOC101488128
uniprot id: A0A3P9B8D0
uniprot id: A0A3P9B8H5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:bbs2
gene id: 106582:bbs2
uniprot id: A0A3P9CH75
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

106582:LOC101483451
gene id: 106582:LOC101483451
uniprot id: A0A3P9BRG5
names: Similarity
messages: Belongs to the FAH family.

106582:sgo1
gene id: 106582:sgo1
uniprot id: A0A3P9BAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

106582:rpl24
gene id: 106582:rpl24
uniprot id: A0A3P9D523
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

106582:mak16
gene id: 106582:mak16
uniprot id: A0A3P9AXQ9
names: Similarity
messages: Belongs to the MAK16 family.

106582:twf1
gene id: 106582:twf1
uniprot id: A0A3P9BNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

106582:cpsf2
gene id: 106582:cpsf2
uniprot id: A0A3P9AXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

106582:LOC101467915
gene id: 106582:LOC101467915
uniprot id: A0A3P9C975
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

106582:LOC101473126
gene id: 106582:LOC101473126
uniprot id: A0A3P9C7A7
uniprot id: A0A3P9C8A8
names: Subcellular Location Annotation
messages: Membrane

106582:chek1
gene id: 106582:chek1
uniprot id: A0A3P9CTV1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

106582:gpr1
gene id: 106582:gpr1
uniprot id: A0A3P9B705
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:nusap1
gene id: 106582:nusap1
uniprot id: A0A3P9BX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

106582:emc8
gene id: 106582:emc8
uniprot id: A0A3P9C2R4
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

106582:LOC101484786
gene id: 106582:LOC101484786
uniprot id: A0A3P9CSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

106582:rpl7l1
gene id: 106582:rpl7l1
uniprot id: A0A3P9CED6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

106582:LOC101484821
gene id: 106582:LOC101484821
uniprot id: A0A3P9AYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101477307
gene id: 106582:LOC101477307
uniprot id: A0A3P9BSM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101481558
gene id: 106582:LOC101481558
uniprot id: A0A3P9ATS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:mgat5
gene id: 106582:mgat5
uniprot id: A0A3P9B3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

106582:LOC101474561
gene id: 106582:LOC101474561
uniprot id: A0A3P9CB98
names: Similarity
messages: Belongs to the SKI family.

106582:LOC101482544
gene id: 106582:LOC101482544
uniprot id: A0A3P9BL95
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

106582:tekt1
gene id: 106582:tekt1
uniprot id: A0A3P9B549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

106582:cav3
gene id: 106582:cav3
uniprot id: A0A3P9BVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

106582:LOC101486012
gene id: 106582:LOC101486012
uniprot id: A0A3P9BK45
names: Similarity
messages: Belongs to the peptidase C2 family.

106582:lg12h9orf64
gene id: 106582:lg12h9orf64
uniprot id: A0A3P9B7X2
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

106582:LOC101478146
gene id: 106582:LOC101478146
uniprot id: A0A3P9C4S0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

106582:hebp1
gene id: 106582:hebp1
uniprot id: A0A3P9B9V9
names: Similarity
messages: Belongs to the HEBP family.

106582:LOC101486939
gene id: 106582:LOC101486939
uniprot id: A0A3P9BSL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

106582:mrto4
gene id: 106582:mrto4
uniprot id: A0A3P9C9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

106582:LOC101475683
gene id: 106582:LOC101475683
uniprot id: A0A3P9CJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

106582:LOC105940915
gene id: 106582:LOC105940915
uniprot id: A0A3P9DS60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:rps11
gene id: 106582:rps11
uniprot id: A0A3P9D7E8
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

106582:hspb1
gene id: 106582:hspb1
uniprot id: A0A3P9DAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

106582:LOC101464867
gene id: 106582:LOC101464867
uniprot id: A0A3P9BBF6
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

106582:LOC101477931
gene id: 106582:LOC101477931
uniprot id: A0A3P9CVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

106582:mtx2
gene id: 106582:mtx2
uniprot id: A0A3P9DQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:LOC101476133
gene id: 106582:LOC101476133
uniprot id: A0A3P9BAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

106582:LOC101465608
gene id: 106582:LOC101465608
uniprot id: A0A3P9AV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

106582:LOC101465527
gene id: 106582:LOC101465527
uniprot id: A0A3P9DJT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101485212
gene id: 106582:LOC101485212
uniprot id: A0A3P9BGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

106582:tmem88
gene id: 106582:tmem88
uniprot id: A0A3P9B813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

106582:dynlt1
gene id: 106582:dynlt1
uniprot id: A0A3P9CPY5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

106582:chfr
gene id: 106582:chfr
uniprot id: A0A3P9CTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

106582:pdk4
gene id: 106582:pdk4
uniprot id: A0A3P9BNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

106582:LOC101468195
gene id: 106582:LOC101468195
uniprot id: A0A3P9CRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane
messages: Plasma membrane anion exchange protein of wide distribution.

106582:LOC101468965
gene id: 106582:LOC101468965
uniprot id: A0A3P9C7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

106582:LOC101471320
gene id: 106582:LOC101471320
uniprot id: A0A3P9C487
names: Similarity
messages: Belongs to the peptidase M14 family.

106582:eif3m
gene id: 106582:eif3m
uniprot id: A0A3P9C166
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

106582:ptgir
gene id: 106582:ptgir
uniprot id: A0A3P9CHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:serpind1
gene id: 106582:serpind1
uniprot id: A0A3P9BVH2
names: Similarity
messages: Belongs to the serpin family.

106582:LOC101481134
gene id: 106582:LOC101481134
uniprot id: A0A3P9C4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

106582:rhot2
gene id: 106582:rhot2
uniprot id: A0A3P9BZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

106582:LOC101477126
gene id: 106582:LOC101477126
uniprot id: A0A3P9BJ03
names: Similarity
messages: Belongs to the globin family.

106582:trub2
gene id: 106582:trub2
uniprot id: A0A3P9CHK5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

106582:emc9
gene id: 106582:emc9
uniprot id: A0A3P9CWS1
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

106582:LOC101487224
gene id: 106582:LOC101487224
uniprot id: A0A3P9CA91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

106582:slc6a15
gene id: 106582:slc6a15
uniprot id: A0A3P9C4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:atg12
gene id: 106582:atg12
uniprot id: A0A3P9CJG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

106582:aacs
gene id: 106582:aacs
uniprot id: A0A3P9C5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

106582:mkx
gene id: 106582:mkx
uniprot id: A0A3P9CLR2
names: Subcellular Location Annotation
messages: Nucleus

106582:pdc
gene id: 106582:pdc
uniprot id: A0A3P9CSW3
names: Similarity
messages: Belongs to the phosducin family.

106582:fa2h
gene id: 106582:fa2h
uniprot id: A0A3P9BTN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:lzic
gene id: 106582:lzic
uniprot id: A0A3P9C6K9
names: Similarity
messages: Belongs to the CTNNBIP1 family.

106582:LOC101470358
gene id: 106582:LOC101470358
uniprot id: A0A3P9CCJ1
uniprot id: A0A3P9CCJ5
names: Similarity
messages: Belongs to the zygin family.

106582:LOC101487597
gene id: 106582:LOC101487597
uniprot id: A0A3P9C2K8
names: Similarity
messages: Belongs to the PPP phosphatase family.

106582:kcnab2
gene id: 106582:kcnab2
uniprot id: A0A3P9C986
uniprot id: A0A3P9C9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

106582:ftsj3
gene id: 106582:ftsj3
uniprot id: A0A3P9AXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

106582:LOC101478712
gene id: 106582:LOC101478712
uniprot id: A0A3P9AT11
uniprot id: A0A3P9AT67
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

106582:lg5h6orf89
gene id: 106582:lg5h6orf89
uniprot id: A0A3P9CKW1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101474926
gene id: 106582:LOC101474926
uniprot id: A0A3P9C8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

106582:LOC101472171
gene id: 106582:LOC101472171
uniprot id: A0A3P9AVU3
names: Subcellular Location Annotation
messages: Nucleus

106582:adssl1
gene id: 106582:adssl1
uniprot id: A0A3P9DPK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

106582:LOC101469195
gene id: 106582:LOC101469195
uniprot id: A0A3P9BTG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

106582:LOC101468064
gene id: 106582:LOC101468064
uniprot id: A0A3P9B270
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:ca14
gene id: 106582:ca14
uniprot id: A0A3P9CH94
uniprot id: A0A3P9CHA4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

106582:slc35c2
gene id: 106582:slc35c2
uniprot id: A0A3P9D643
names: Subcellular Location Annotation
messages: Membrane

106582:lbr
gene id: 106582:lbr
uniprot id: A0A3P9CFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

106582:LOC101480018
gene id: 106582:LOC101480018
uniprot id: A0A3P9B2B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

106582:supt20h
gene id: 106582:supt20h
uniprot id: A0A3P9DER5
names: Similarity
messages: Belongs to the SPT20 family.

106582:LOC101482602
gene id: 106582:LOC101482602
uniprot id: A0A3P9BMN4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:LOC105940423
gene id: 106582:LOC105940423
uniprot id: A0A3P9BX39
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

106582:dxo
gene id: 106582:dxo
uniprot id: A0A3P9B4I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

106582:LOC101485798
gene id: 106582:LOC101485798
uniprot id: A0A3P9DEK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

106582:LOC101483609
gene id: 106582:LOC101483609
uniprot id: A0A3P9AUA9
uniprot id: A0A3P9AUC2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101470971
gene id: 106582:LOC101470971
uniprot id: A0A3P9DPD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101467517
gene id: 106582:LOC101467517
uniprot id: A0A3P9B6X0
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

106582:LOC101479283
gene id: 106582:LOC101479283
uniprot id: A0A3P9C556
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101465958
gene id: 106582:LOC101465958
uniprot id: A0A3P9DS97
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

106582:LOC101476292
gene id: 106582:LOC101476292
uniprot id: A0A3P9BCD5
names: Similarity
messages: Belongs to the calponin family.

106582:jagn1
gene id: 106582:jagn1
uniprot id: A0A3P9CNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:vta1
gene id: 106582:vta1
uniprot id: A0A3P9CA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

106582:LOC101484650
gene id: 106582:LOC101484650
uniprot id: A0A3P9DBZ9
uniprot id: A0A3P9DD21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

106582:LOC101482153
gene id: 106582:LOC101482153
uniprot id: A0A3P9BLF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101479803
gene id: 106582:LOC101479803
uniprot id: A0A3P9CX45
uniprot id: A0A3P9CXV9
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

106582:LOC101469013
gene id: 106582:LOC101469013
uniprot id: A0A3P9B4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

106582:fgf3
gene id: 106582:fgf3
uniprot id: A0A3P9CL02
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101470595
gene id: 106582:LOC101470595
uniprot id: A0A3P9CE58
names: Similarity
messages: Belongs to the TMEM178 family.

106582:LOC101476876
gene id: 106582:LOC101476876
uniprot id: A0A3P9CYI0
names: Similarity
messages: Belongs to the actin family.

106582:nploc4
gene id: 106582:nploc4
uniprot id: A0A3P9BSY4
names: Similarity
messages: Belongs to the NPL4 family.

106582:grem2
gene id: 106582:grem2
uniprot id: A0A3P9DRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

106582:LOC101472079
gene id: 106582:LOC101472079
uniprot id: A0A3P9AWK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

106582:kctd10
gene id: 106582:kctd10
uniprot id: A0A3P9CHP3
names: Similarity
messages: Belongs to the BACURD family.

106582:slc25a28
gene id: 106582:slc25a28
uniprot id: A0A3P9DSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:dnase2
gene id: 106582:dnase2
uniprot id: A0A3P9CGX3
names: Similarity
messages: Belongs to the DNase II family.

106582:yrdc
gene id: 106582:yrdc
uniprot id: A0A3P9BGX1
names: Similarity
messages: Belongs to the SUA5 family.

106582:hcrtr2
gene id: 106582:hcrtr2
uniprot id: A0A3P9B8P4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101479993
gene id: 106582:LOC101479993
uniprot id: A0A3P9DNA2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

106582:ap3b1
gene id: 106582:ap3b1
uniprot id: A0A3P9BEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

106582:LOC101486157
gene id: 106582:LOC101486157
uniprot id: A0A3P9C498
uniprot id: A0A3P9C5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

106582:LOC101471750
gene id: 106582:LOC101471750
uniprot id: A0A3P9DMK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101480382
gene id: 106582:LOC101480382
uniprot id: A0A3P9D1K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

106582:klhl22
gene id: 106582:klhl22
uniprot id: A0A3P9BH84
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

106582:LOC101478980
gene id: 106582:LOC101478980
uniprot id: A0A3P9D8E6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

106582:pou2f1
gene id: 106582:pou2f1
uniprot id: A0A3P9D4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

106582:tubgcp4
gene id: 106582:tubgcp4
uniprot id: A0A3P9CG09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

106582:LOC101471900
gene id: 106582:LOC101471900
uniprot id: A0A3P9CFE8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

106582:def8
gene id: 106582:def8
uniprot id: A0A3P9C384
names: Similarity
messages: Belongs to the DEF8 family.

106582:slitrk6
gene id: 106582:slitrk6
uniprot id: A0A3P9B892
names: Similarity
messages: Belongs to the SLITRK family.

106582:LOC101481538
gene id: 106582:LOC101481538
uniprot id: A0A3P9DNQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101464601
gene id: 106582:LOC101464601
uniprot id: A0A3P9D167
names: Subcellular Location Annotation
messages: Nucleus

106582:chd9
gene id: 106582:chd9
uniprot id: A0A3P9BFQ5
uniprot id: A0A3P9BFY3
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

106582:banf1
gene id: 106582:banf1
uniprot id: A0A3P9C5S6
names: Subcellular Location Annotation
messages: Nucleus

106582:samd4b
gene id: 106582:samd4b
uniprot id: A0A3P9BI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

106582:LOC101486457
gene id: 106582:LOC101486457
uniprot id: A0A3P9C352
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

106582:LOC101479095
gene id: 106582:LOC101479095
uniprot id: A0A3P9CEQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101470533
gene id: 106582:LOC101470533
uniprot id: A0A3P9DIW1
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101481427
gene id: 106582:LOC101481427
uniprot id: A0A3P9BHR9
uniprot id: A0A3P9BHW8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476262
gene id: 106582:LOC101476262
uniprot id: A0A3P9DQK4
names: Subcellular Location Annotation
messages: Nucleus

106582:samd8
gene id: 106582:samd8
uniprot id: A0A3P9CHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

106582:LOC101473740
gene id: 106582:LOC101473740
uniprot id: A0A3P9BVV2
names: Subcellular Location Annotation
messages: Nucleus

106582:hoxd10
gene id: 106582:hoxd10
uniprot id: A0A3P9B879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:LOC101473098
gene id: 106582:LOC101473098
uniprot id: A0A3P9BHJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:foxk1
gene id: 106582:foxk1
uniprot id: A0A3P9C2G8
names: Subcellular Location Annotation
messages: Nucleus

106582:nck1
gene id: 106582:nck1
uniprot id: A0A3P9CPG0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

106582:LOC101474827
gene id: 106582:LOC101474827
uniprot id: A0A3P9CCN8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

106582:vangl2
gene id: 106582:vangl2
uniprot id: A0A3P9DE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

106582:grk3
gene id: 106582:grk3
uniprot id: A0A3P9C1Q8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

106582:LOC101469024
gene id: 106582:LOC101469024
uniprot id: A0A3P9BWW9
names: Similarity
messages: Belongs to the alpha-actinin family.

106582:tvp23b
gene id: 106582:tvp23b
uniprot id: A0A3P9BRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

106582:LOC101474337
gene id: 106582:LOC101474337
uniprot id: A0A3P9BNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

106582:kpna2
gene id: 106582:kpna2
uniprot id: A0A3P9AWT1
names: Similarity
messages: Belongs to the importin alpha family.

106582:LOC101471550
gene id: 106582:LOC101471550
uniprot id: A0A3P9DLU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

106582:LOC101477216
gene id: 106582:LOC101477216
uniprot id: A0A3P9B8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:LOC101469147
gene id: 106582:LOC101469147
uniprot id: A0A3P9AX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

106582:LOC101475481
gene id: 106582:LOC101475481
uniprot id: A0A3P9C3M8
names: Subunit
messages: Monomer.

106582:csnk1g1
gene id: 106582:csnk1g1
uniprot id: A0A3P9C7Z5
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

106582:LOC101483804
gene id: 106582:LOC101483804
uniprot id: A0A3P9AZV8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

106582:aes
gene id: 106582:aes
uniprot id: A0A3P9BPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

106582:LOC101483517
gene id: 106582:LOC101483517
uniprot id: A0A3P9ASB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

106582:LOC101476513
gene id: 106582:LOC101476513
uniprot id: A0A3P9AY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

106582:rabggta
gene id: 106582:rabggta
uniprot id: A0A3P9CY03
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

106582:LOC101477411
gene id: 106582:LOC101477411
uniprot id: A0A3P9BH93
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106582:LOC101487833
gene id: 106582:LOC101487833
uniprot id: A0A3P9CJJ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101469110
gene id: 106582:LOC101469110
uniprot id: A0A3P9DQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

106582:LOC101478402
gene id: 106582:LOC101478402
uniprot id: A0A3P9BG99
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:tmc8
gene id: 106582:tmc8
uniprot id: A0A3P9BLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

106582:adgra2
gene id: 106582:adgra2
uniprot id: A0A3P9C0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

106582:LOC101481141
gene id: 106582:LOC101481141
uniprot id: A0A3P9CIU3
names: Subcellular Location Annotation
messages: Secreted

106582:LOC101468062
gene id: 106582:LOC101468062
uniprot id: A0A3P9BX96
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

106582:rpf2
gene id: 106582:rpf2
uniprot id: A0A3P9CEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

106582:LOC101468325
gene id: 106582:LOC101468325
uniprot id: A0A3P9CKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

106582:LOC101485526
gene id: 106582:LOC101485526
uniprot id: A0A3P9BD63
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101470293
gene id: 106582:LOC101470293
uniprot id: A0A3P9BI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

106582:jpt1
gene id: 106582:jpt1
uniprot id: A0A3P9C4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

106582:srd5a3
gene id: 106582:srd5a3
uniprot id: A0A3P9CXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

106582:LOC101478311
gene id: 106582:LOC101478311
uniprot id: A0A3P9D3N6
names: Similarity
messages: Belongs to the SZRD1 family.

106582:LOC106674721
gene id: 106582:LOC106674721
uniprot id: A0A3P9AX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101476539
gene id: 106582:LOC101476539
uniprot id: A0A3P9D7U5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

106582:LOC101485952
gene id: 106582:LOC101485952
uniprot id: A0A3P9C8X0
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

106582:LOC101475575
gene id: 106582:LOC101475575
uniprot id: A0A3P9BTI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

106582:LOC101471328
gene id: 106582:LOC101471328
uniprot id: A0A3P9DIB3
names: Similarity
messages: Belongs to the PP2C family.

106582:LOC101464675
gene id: 106582:LOC101464675
uniprot id: A0A3P9AX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

106582:neurod1
gene id: 106582:neurod1
uniprot id: A0A3P9D3J4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:pcnx4
gene id: 106582:pcnx4
uniprot id: A0A3P9BJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

106582:LOC101485140
gene id: 106582:LOC101485140
uniprot id: A0A3P9D8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

106582:coq9
gene id: 106582:coq9
uniprot id: A0A3P9CDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

106582:atp2b2
gene id: 106582:atp2b2
uniprot id: A0A3P9C7Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:eif4ebp2
gene id: 106582:eif4ebp2
uniprot id: A0A3P9DRY6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

106582:hsd17b3
gene id: 106582:hsd17b3
uniprot id: A0A3P9BFT1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:atp2b1
gene id: 106582:atp2b1
uniprot id: A0A3P9BFJ6
uniprot id: A0A3P9BFL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:eif2s2
gene id: 106582:eif2s2
uniprot id: A0A3P9D020
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

106582:fam72a
gene id: 106582:fam72a
uniprot id: A0A3P9AT61
names: Similarity
messages: Belongs to the FAM72 family.

106582:dvl3
gene id: 106582:dvl3
uniprot id: A0A3P9B149
names: Similarity
messages: Belongs to the DSH family.

106582:LOC101476618
gene id: 106582:LOC101476618
uniprot id: A0A3P9C8S8
uniprot id: A0A3P9C8Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

106582:khdrbs3
gene id: 106582:khdrbs3
uniprot id: A0A3P9AXN9
names: Similarity
messages: Belongs to the KHDRBS family.

106582:sgk1
gene id: 106582:sgk1
uniprot id: A0A3P9CEX0
uniprot id: A0A3P9CEZ6
uniprot id: A0A3P9CFA9
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:dusp26
gene id: 106582:dusp26
uniprot id: A0A3P9BT30
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

106582:LOC101471457
gene id: 106582:LOC101471457
uniprot id: A0A3P9CAB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101484387
gene id: 106582:LOC101484387
uniprot id: A0A3P9DKM2
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

106582:fbxo32
gene id: 106582:fbxo32
uniprot id: A0A3P9BCU2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473971
gene id: 106582:LOC101473971
uniprot id: A0A3P9B4W4
uniprot id: A0A3P9B4X2
names: Subcellular Location Annotation
messages: cytoskeleton

106582:LOC101471956
gene id: 106582:LOC101471956
uniprot id: A0A3P9ATP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

106582:LOC101469828
gene id: 106582:LOC101469828
uniprot id: A0A3P9CNW1
names: Subcellular Location Annotation
messages: Membrane

106582:foxi2
gene id: 106582:foxi2
uniprot id: A0A3P9AYM7
names: Subcellular Location Annotation
messages: Nucleus

106582:ndufb9
gene id: 106582:ndufb9
uniprot id: A0A3P9DQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

106582:dnal4
gene id: 106582:dnal4
uniprot id: A0A3P9BFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

106582:ppp1r12a
gene id: 106582:ppp1r12a
uniprot id: A0A3P9AXB2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

106582:LOC101481802
gene id: 106582:LOC101481802
uniprot id: A0A3P9BW81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:xrcc3
gene id: 106582:xrcc3
uniprot id: A0A3P9CCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

106582:steap3
gene id: 106582:steap3
uniprot id: A0A3P9B4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

106582:erap2
gene id: 106582:erap2
uniprot id: A0A3P9CLX1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101465875
gene id: 106582:LOC101465875
uniprot id: A0A3P9DB12
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

106582:samm50
gene id: 106582:samm50
uniprot id: A0A3P9C0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

106582:LOC101470563
gene id: 106582:LOC101470563
uniprot id: A0A3P9CZ26
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:rpl23
gene id: 106582:rpl23
uniprot id: A0A3P9AU55
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

106582:erc2
gene id: 106582:erc2
uniprot id: A0A3P9C302
uniprot id: A0A3P9C3F7
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101464835
gene id: 106582:LOC101464835
uniprot id: A0A3P9CBZ9
names: Similarity
messages: Belongs to the dickkopf family.

106582:LOC101479411
gene id: 106582:LOC101479411
uniprot id: A0A3P9CMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

106582:cpeb1
gene id: 106582:cpeb1
uniprot id: A0A3P9C875
names: Similarity
messages: Belongs to the RRM CPEB family.

106582:tprg1l
gene id: 106582:tprg1l
uniprot id: A0A3P9CZI9
names: Similarity
messages: Belongs to the TPRG1 family.

106582:rorb
gene id: 106582:rorb
uniprot id: A0A3P9BVS8
uniprot id: A0A3P9BVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:sfxn4
gene id: 106582:sfxn4
uniprot id: A0A3P9C0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

106582:slc9a3r2
gene id: 106582:slc9a3r2
uniprot id: A0A3P9BIP0
names: Subcellular Location Annotation
messages: Endomembrane system

106582:phkb
gene id: 106582:phkb
uniprot id: A0A3P9B6A7
uniprot id: A0A3P9B6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

106582:ppfibp1
gene id: 106582:ppfibp1
uniprot id: A0A3P9CSR3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

106582:LOC101472973
gene id: 106582:LOC101472973
uniprot id: A0A3P9CRL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

106582:pcsk7
gene id: 106582:pcsk7
uniprot id: A0A3P9BCH7
names: Similarity
messages: Belongs to the peptidase S8 family.

106582:mcts1
gene id: 106582:mcts1
uniprot id: A0A3P9BK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

106582:LOC101474919
gene id: 106582:LOC101474919
uniprot id: A0A3P9C3Q2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101482971
gene id: 106582:LOC101482971
uniprot id: A0A3P9DB87
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:sgta
gene id: 106582:sgta
uniprot id: A0A3P9B1W1
names: Similarity
messages: Belongs to the SGT family.

106582:LOC101467985
gene id: 106582:LOC101467985
uniprot id: A0A3P9DMU2
names: Similarity
messages: Belongs to the S-100 family.

106582:LOC101465489
gene id: 106582:LOC101465489
uniprot id: A0A3P9AX61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101477201
gene id: 106582:LOC101477201
uniprot id: A0A3P9CT08
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101464684
gene id: 106582:LOC101464684
uniprot id: A0A3P9DMX2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:LOC101487896
gene id: 106582:LOC101487896
uniprot id: A0A3P9BQ71
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

106582:rln3
gene id: 106582:rln3
uniprot id: A0A3P9BJ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

106582:gtf2f2
gene id: 106582:gtf2f2
uniprot id: A0A3P9B8Y1
uniprot id: A0A3P9B922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

106582:fgf12
gene id: 106582:fgf12
uniprot id: A0A3P9DG60
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101469585
gene id: 106582:LOC101469585
uniprot id: A0A3P9DDI1
names: Subcellular Location Annotation
messages: Nucleus

106582:irf2
gene id: 106582:irf2
uniprot id: A0A3P9B8G1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:ppp2r2d
gene id: 106582:ppp2r2d
uniprot id: A0A3P9DS09
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

106582:LOC101472831
gene id: 106582:LOC101472831
uniprot id: A0A3P9C893
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

106582:LOC101487895
gene id: 106582:LOC101487895
uniprot id: A0A3P9BFU7
names: Similarity
messages: Belongs to the KHDC4 family.

106582:gnb1
gene id: 106582:gnb1
uniprot id: A0A3P9D294
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

106582:LOC101480967
gene id: 106582:LOC101480967
uniprot id: A0A3P9D6N9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101471998
gene id: 106582:LOC101471998
uniprot id: A0A3P9C707
names: Subcellular Location Annotation
messages: Membrane

106582:tmcc2
gene id: 106582:tmcc2
uniprot id: A0A3P9BXK2
names: Similarity
messages: Belongs to the TEX28 family.

106582:tbp
gene id: 106582:tbp
uniprot id: A0A3P9BY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

106582:lgi3
gene id: 106582:lgi3
uniprot id: A0A3P9BJP1
names: Subcellular Location Annotation
messages: Secreted

106582:trnau1ap
gene id: 106582:trnau1ap
uniprot id: A0A3P9CMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

106582:pkd2
gene id: 106582:pkd2
uniprot id: A0A3P9CUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

106582:grk1
gene id: 106582:grk1
uniprot id: A0A3P9B132
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

106582:rpn2
gene id: 106582:rpn2
uniprot id: A0A3P9BLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

106582:ireb2
gene id: 106582:ireb2
uniprot id: A0A3P9BXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

106582:LOC101477985
gene id: 106582:LOC101477985
uniprot id: A0A3P9BNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

106582:nr1i2
gene id: 106582:nr1i2
uniprot id: A0A3P9AWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:nit1
gene id: 106582:nit1
uniprot id: A0A3P9D1B5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

106582:LOC101470002
gene id: 106582:LOC101470002
uniprot id: A0A3P9B399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106582:LOC101473415
gene id: 106582:LOC101473415
uniprot id: A0A3P9B5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

106582:LOC101485255
gene id: 106582:LOC101485255
uniprot id: A0A3P9AXA7
names: Similarity
messages: Belongs to the SNF7 family.

106582:gabrg2
gene id: 106582:gabrg2
uniprot id: A0A3P9BN72
uniprot id: A0A3P9BN92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101472435
gene id: 106582:LOC101472435
uniprot id: A0A3P9D3Y9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

106582:LOC101486362
gene id: 106582:LOC101486362
uniprot id: A0A3P9DHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

106582:LOC101465246
gene id: 106582:LOC101465246
uniprot id: A0A3P9AX21
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

106582:LOC101467415
gene id: 106582:LOC101467415
uniprot id: A0A3P9AYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:LOC101487206
gene id: 106582:LOC101487206
uniprot id: A0A3P9B1Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

106582:LOC101472848
gene id: 106582:LOC101472848
uniprot id: A0A3P9BEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

106582:ctsd
gene id: 106582:ctsd
uniprot id: A0A3P9CI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

106582:LOC101465583
gene id: 106582:LOC101465583
uniprot id: A0A3P9DB32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:rarb
gene id: 106582:rarb
uniprot id: A0A3P9CLG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

106582:plpp4
gene id: 106582:plpp4
uniprot id: A0A3P9BWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:pex7
gene id: 106582:pex7
uniprot id: A0A3P9C8Y9
uniprot id: A0A3P9C935
uniprot id: A0A3P9C948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

106582:LOC101474701
gene id: 106582:LOC101474701
uniprot id: A0A3P9CVR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101485959
gene id: 106582:LOC101485959
uniprot id: A0A3P9B3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

106582:fscn2
gene id: 106582:fscn2
uniprot id: A0A3P9BQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

106582:LOC101472367
gene id: 106582:LOC101472367
uniprot id: A0A3P9CKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:tmem116
gene id: 106582:tmem116
uniprot id: A0A3P9CLG0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101467281
gene id: 106582:LOC101467281
uniprot id: A0A3P9B6B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:elmo3
gene id: 106582:elmo3
uniprot id: A0A3P9CIH2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

106582:plcb3
gene id: 106582:plcb3
uniprot id: A0A3P9B1T5
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

106582:LOC101467059
gene id: 106582:LOC101467059
uniprot id: A0A3P9BFC7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

106582:LOC101487137
gene id: 106582:LOC101487137
uniprot id: A0A3P9DPW3
names: Similarity
messages: Belongs to the CAMK2N family.

106582:cpsf6
gene id: 106582:cpsf6
uniprot id: A0A3P9BKY9
uniprot id: A0A3P9BL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

106582:cops4
gene id: 106582:cops4
uniprot id: A0A3P9BIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

106582:LOC101487440
gene id: 106582:LOC101487440
uniprot id: A0A3P9D0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

106582:uba52
gene id: 106582:uba52
uniprot id: A0A3P9CIY7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

106582:LOC101468867
gene id: 106582:LOC101468867
uniprot id: A0A3P9BL66
uniprot id: A0A3P9BL71
names: Similarity
messages: Belongs to the PROTOR family.

106582:LOC101473573
gene id: 106582:LOC101473573
uniprot id: A0A3P9CRS4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101478845
gene id: 106582:LOC101478845
uniprot id: A0A3P9CLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:LOC101485599
gene id: 106582:LOC101485599
uniprot id: A0A3P9BT13
names: Similarity
messages: Belongs to the gonadal family.

106582:cog4
gene id: 106582:cog4
uniprot id: A0A3P9C530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

106582:LOC101482586
gene id: 106582:LOC101482586
uniprot id: A0A3P9DM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101481239
gene id: 106582:LOC101481239
uniprot id: A0A3P9C3A2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101465377
gene id: 106582:LOC101465377
uniprot id: A0A3P9D389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

106582:LOC101473061
gene id: 106582:LOC101473061
uniprot id: A0A3P9CJ69
uniprot id: A0A3P9CKL7
names: Similarity
messages: Belongs to the ARTD/PARP family.

106582:LOC101469859
gene id: 106582:LOC101469859
uniprot id: A0A3P9DFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

106582:LOC101470774
gene id: 106582:LOC101470774
uniprot id: A0A3P9DM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

106582:capza2
gene id: 106582:capza2
uniprot id: A0A3P9C6K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

106582:LOC101471344
gene id: 106582:LOC101471344
uniprot id: A0A3P9B6T0
uniprot id: A0A3P9B6W9
names: Similarity
messages: Belongs to the GADD45 family.
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

106582:LOC101484176
gene id: 106582:LOC101484176
uniprot id: A0A3P9B9A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

106582:LOC101466267
gene id: 106582:LOC101466267
uniprot id: A0A3P9BPR3
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

106582:naa60
gene id: 106582:naa60
uniprot id: A0A3P9D895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

106582:taf11
gene id: 106582:taf11
uniprot id: A0A3P9DLI2
names: Similarity
messages: Belongs to the TAF11 family.

106582:LOC101475497
gene id: 106582:LOC101475497
uniprot id: A0A3P9DHJ0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101485940
gene id: 106582:LOC101485940
uniprot id: A0A3P9BYV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

106582:negr1
gene id: 106582:negr1
uniprot id: A0A3P9CQA0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101477883
gene id: 106582:LOC101477883
uniprot id: A0A3P9AQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

106582:mettl26
gene id: 106582:mettl26
uniprot id: A0A3P9BQB0
names: Similarity
messages: Belongs to the UPF0585 family.

106582:LOC101471102
gene id: 106582:LOC101471102
uniprot id: A0A3P9C9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

106582:specc1l
gene id: 106582:specc1l
uniprot id: A0A3P9AYS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

106582:LOC101483656
gene id: 106582:LOC101483656
uniprot id: A0A3P9DKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:tsen15
gene id: 106582:tsen15
uniprot id: A0A3P9BFB7
names: Similarity
messages: Belongs to the SEN15 family.

106582:phc1
gene id: 106582:phc1
uniprot id: A0A3P9CMQ2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484850
gene id: 106582:LOC101484850
uniprot id: A0A3P9CPU4
names: Similarity
messages: Belongs to the Niban family.

106582:LOC101463970
gene id: 106582:LOC101463970
uniprot id: A0A3P9ATK6
names: Similarity
messages: Belongs to the peptidase M16 family.

106582:stxbp1
gene id: 106582:stxbp1
uniprot id: A0A3P9CCV5
uniprot id: A0A3P9CCZ7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

106582:LOC101469026
gene id: 106582:LOC101469026
uniprot id: A0A3P9AVM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

106582:slc6a20
gene id: 106582:slc6a20
uniprot id: A0A3P9DHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101477432
gene id: 106582:LOC101477432
uniprot id: A0A3P9DCW2
names: Subcellular Location Annotation
messages: Nucleus

106582:ehd2
gene id: 106582:ehd2
uniprot id: A0A3P9DE71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

106582:nae1
gene id: 106582:nae1
uniprot id: A0A3P9AZQ1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

106582:LOC101486655
gene id: 106582:LOC101486655
uniprot id: A0A3P9BBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

106582:mmp23b
gene id: 106582:mmp23b
uniprot id: A0A3P9D3L4
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101471474
gene id: 106582:LOC101471474
uniprot id: A0A3P9D9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

106582:LOC101467833
gene id: 106582:LOC101467833
uniprot id: A0A3P9DHD7
uniprot id: A0A3P9DIC7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:dhrs1
gene id: 106582:dhrs1
uniprot id: A0A3P9C2U8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101469388
gene id: 106582:LOC101469388
uniprot id: A0A3P9B9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

106582:dlg5
gene id: 106582:dlg5
uniprot id: A0A3P9DRX4
uniprot id: A0A3P9DS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm

106582:gng3
gene id: 106582:gng3
uniprot id: A0A3P9C6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

106582:LOC101473296
gene id: 106582:LOC101473296
uniprot id: A0A3P9DCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:tatdn2
gene id: 106582:tatdn2
uniprot id: A0A3P9BRM6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

106582:tprkb
gene id: 106582:tprkb
uniprot id: A0A3P9CG06
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

106582:LOC101478235
gene id: 106582:LOC101478235
uniprot id: A0A3P9B2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:znf326
gene id: 106582:znf326
uniprot id: A0A3P9B8J5
names: Similarity
messages: Belongs to the AKAP95 family.

106582:rbm8a
gene id: 106582:rbm8a
uniprot id: A0A3P9CIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

106582:LOC101483369
gene id: 106582:LOC101483369
uniprot id: A0A3P9DSD8
names: Similarity
messages: Belongs to the PPase family.

106582:zdhhc8
gene id: 106582:zdhhc8
uniprot id: A0A3P9CSL1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:LOC101474743
gene id: 106582:LOC101474743
uniprot id: A0A3P9BBK9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101475379
gene id: 106582:LOC101475379
uniprot id: A0A3P9CEJ6
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

106582:guf1
gene id: 106582:guf1
uniprot id: A0A3P9BCX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

106582:LOC101477989
gene id: 106582:LOC101477989
uniprot id: A0A3P9C332
uniprot id: A0A3P9C373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

106582:ctnna2
gene id: 106582:ctnna2
uniprot id: A0A3P9DC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction
messages: axon
messages: cytoskeleton

106582:LOC101463964
gene id: 106582:LOC101463964
uniprot id: A0A3P9AR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

106582:LOC101482275
gene id: 106582:LOC101482275
uniprot id: A0A3P9C9B2
names: Subcellular Location Annotation
messages: Membrane

106582:aqp4
gene id: 106582:aqp4
uniprot id: A0A3P9DHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

106582:maco1
gene id: 106582:maco1
uniprot id: A0A3P9BFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

106582:LOC101472119
gene id: 106582:LOC101472119
uniprot id: A0A3P9BVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

106582:nfic
gene id: 106582:nfic
uniprot id: A0A3P9CPL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

106582:msrb3
gene id: 106582:msrb3
uniprot id: A0A3P9CUG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

106582:LOC101467151
gene id: 106582:LOC101467151
uniprot id: A0A3P9AUT7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

106582:LOC101468050
gene id: 106582:LOC101468050
uniprot id: A0A3P9BGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:LOC101464923
gene id: 106582:LOC101464923
uniprot id: A0A3P9B5Z2
names: Subcellular Location Annotation
messages: Membrane

106582:tmem97
gene id: 106582:tmem97
uniprot id: A0A3P9AYB9
names: Subcellular Location Annotation
messages: Membrane

106582:sgpl1
gene id: 106582:sgpl1
uniprot id: A0A3P9BZN0
names: Similarity
messages: Belongs to the group II decarboxylase family.

106582:senp8
gene id: 106582:senp8
uniprot id: A0A3P9C6T7
names: Similarity
messages: Belongs to the peptidase C48 family.

106582:med29
gene id: 106582:med29
uniprot id: A0A3P9CGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

106582:LOC101485823
gene id: 106582:LOC101485823
uniprot id: A0A3P9DTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101467201
gene id: 106582:LOC101467201
uniprot id: A0A3P9CTT2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:trarg1
gene id: 106582:trarg1
uniprot id: A0A3P9CCF1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:LOC101486609
gene id: 106582:LOC101486609
uniprot id: A0A3P9BAZ5
uniprot id: A0A3P9BB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101486679
gene id: 106582:LOC101486679
uniprot id: A0A3P9D4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:gtf2h3
gene id: 106582:gtf2h3
uniprot id: A0A3P9AVR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

106582:LOC101463651
gene id: 106582:LOC101463651
uniprot id: A0A3P9BMU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

106582:tk1
gene id: 106582:tk1
uniprot id: A0A3P9BLG5
names: Similarity
messages: Belongs to the thymidine kinase family.

106582:sod3
gene id: 106582:sod3
uniprot id: A0A3P9D7I9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

106582:LOC101473175
gene id: 106582:LOC101473175
uniprot id: A0A3P9BQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

106582:LOC101485344
gene id: 106582:LOC101485344
uniprot id: A0A3P9BV81
names: Similarity
messages: Belongs to the Bcl-2 family.

106582:LOC101469259
gene id: 106582:LOC101469259
uniprot id: A0A3P9B336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:spns2
gene id: 106582:spns2
uniprot id: A0A3P9D9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

106582:tmlhe
gene id: 106582:tmlhe
uniprot id: A0A3P9C7Y0
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

106582:ubp1
gene id: 106582:ubp1
uniprot id: A0A3P9BBZ1
uniprot id: A0A3P9BC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

106582:slc6a2
gene id: 106582:slc6a2
uniprot id: A0A3P9BH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:LOC101467042
gene id: 106582:LOC101467042
uniprot id: A0A3P9AWY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:hspa9
gene id: 106582:hspa9
uniprot id: A0A3P9B6P7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:LOC101480216
gene id: 106582:LOC101480216
uniprot id: A0A3P9C5T3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

106582:LOC101482738
gene id: 106582:LOC101482738
uniprot id: A0A3P9DPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

106582:LOC101484072
gene id: 106582:LOC101484072
uniprot id: A0A3P9DNM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101478860
gene id: 106582:LOC101478860
uniprot id: A0A3P9BZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

106582:egr1
gene id: 106582:egr1
uniprot id: A0A3P9C2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

106582:kiz
gene id: 106582:kiz
uniprot id: A0A3P9BD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

106582:plin2
gene id: 106582:plin2
uniprot id: A0A3P9AZE1
names: Similarity
messages: Belongs to the perilipin family.

106582:gabra4
gene id: 106582:gabra4
uniprot id: A0A3P9BCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:LOC101474203
gene id: 106582:LOC101474203
uniprot id: A0A3P9DC30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

106582:trpv4
gene id: 106582:trpv4
uniprot id: A0A3P9CHP7
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101466481
gene id: 106582:LOC101466481
uniprot id: A0A3P9AU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

106582:LOC101473907
gene id: 106582:LOC101473907
uniprot id: A0A3P9CEV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

106582:serp2
gene id: 106582:serp2
uniprot id: A0A3P9BXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

106582:phtf2
gene id: 106582:phtf2
uniprot id: A0A3P9BM79
names: Subcellular Location Annotation
messages: Membrane

106582:tpm1
gene id: 106582:tpm1
uniprot id: A0A3P9D637
uniprot id: A0A3P9D797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

106582:LOC101478005
gene id: 106582:LOC101478005
uniprot id: A0A3P9BZH6
uniprot id: A0A3P9C0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

106582:LOC101468263
gene id: 106582:LOC101468263
uniprot id: A0A3P9CUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:rab9a
gene id: 106582:rab9a
uniprot id: A0A3P9B041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

106582:csnk1a1
gene id: 106582:csnk1a1
uniprot id: A0A3P9CM36
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101479785
gene id: 106582:LOC101479785
uniprot id: A0A3P9BRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

106582:LOC101471088
gene id: 106582:LOC101471088
uniprot id: A0A3P9B838
names: Similarity
messages: Belongs to the PRORSD1 family.

106582:ndrg4
gene id: 106582:ndrg4
uniprot id: A0A3P9CGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

106582:epha3
gene id: 106582:epha3
uniprot id: A0A3P9BW45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101479659
gene id: 106582:LOC101479659
uniprot id: A0A3P9DP86
names: Similarity
messages: Belongs to the KHDRBS family.

106582:pigs
gene id: 106582:pigs
uniprot id: A0A3P9CT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101487707
gene id: 106582:LOC101487707
uniprot id: A0A3P9CFJ0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

106582:ube2n
gene id: 106582:ube2n
uniprot id: A0A3P9CSF0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:rps29
gene id: 106582:rps29
uniprot id: A0A3P9C2J2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

106582:ccs
gene id: 106582:ccs
uniprot id: A0A3P9D033
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

106582:LOC101477720
gene id: 106582:LOC101477720
uniprot id: A0A3P9CPS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

106582:LOC101466352
gene id: 106582:LOC101466352
uniprot id: A0A3P9B731
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

106582:zic2
gene id: 106582:zic2
uniprot id: A0A3P9D300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:sept5
gene id: 106582:sept5
uniprot id: A0A3P9BSR4
uniprot id: A0A3P9BSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

106582:afg3l2
gene id: 106582:afg3l2
uniprot id: A0A3P9CVC6
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

106582:LOC101467831
gene id: 106582:LOC101467831
uniprot id: A0A3P9BPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

106582:ip6k1
gene id: 106582:ip6k1
uniprot id: A0A3P9CHN9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

106582:LOC101465466
gene id: 106582:LOC101465466
uniprot id: A0A3P9CWQ3
names: Subcellular Location Annotation
messages: Membrane

106582:adamts14
gene id: 106582:adamts14
uniprot id: A0A3P9ATI3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:rad1
gene id: 106582:rad1
uniprot id: A0A3P9CW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

106582:LOC101485811
gene id: 106582:LOC101485811
uniprot id: A0A3P9B262
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106582:hoxc9
gene id: 106582:hoxc9
uniprot id: A0A3P9DQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

106582:atp6v0b
gene id: 106582:atp6v0b
uniprot id: A0A3P9DEV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

106582:atg2a
gene id: 106582:atg2a
uniprot id: A0A3P9B8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

106582:glrb
gene id: 106582:glrb
uniprot id: A0A3P9AWU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:nkx6-3
gene id: 106582:nkx6-3
uniprot id: A0A3P9BZN5
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101466602
gene id: 106582:LOC101466602
uniprot id: A0A3P9BM88
names: Similarity
messages: Belongs to the CRISP family.

106582:LOC101487885
gene id: 106582:LOC101487885
uniprot id: A0A3P9C2I5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

106582:LOC101472896
gene id: 106582:LOC101472896
uniprot id: A0A3P9AVV5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:vps53
gene id: 106582:vps53
uniprot id: A0A3P9CB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

106582:fmc1
gene id: 106582:fmc1
uniprot id: A0A3P9BA69
names: Similarity
messages: Belongs to the FMC1 family.

106582:LOC101476643
gene id: 106582:LOC101476643
uniprot id: A0A3P9BRB4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:sptssb
gene id: 106582:sptssb
uniprot id: A0A3P9CJR0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:dscc1
gene id: 106582:dscc1
uniprot id: A0A3P9DIU5
names: Similarity
messages: Belongs to the DCC1 family.

106582:rspo2
gene id: 106582:rspo2
uniprot id: A0A3P9BZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

106582:oma1
gene id: 106582:oma1
uniprot id: A0A3P9CVI3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

106582:slc50a1
gene id: 106582:slc50a1
uniprot id: A0A3P9CE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

106582:sf3a3
gene id: 106582:sf3a3
uniprot id: A0A3P9CKW3
names: Similarity
messages: Belongs to the SF3A3 family.

106582:LOC101464457
gene id: 106582:LOC101464457
uniprot id: A0A3P9DHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

106582:LOC101466644
gene id: 106582:LOC101466644
uniprot id: A0A3P9BJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:slc16a5
gene id: 106582:slc16a5
uniprot id: A0A3P9BPC6
names: Subcellular Location Annotation
messages: Membrane

106582:aadacl4
gene id: 106582:aadacl4
uniprot id: A0A3P9AV71
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

106582:LOC101486429
gene id: 106582:LOC101486429
uniprot id: A0A3P9B9V8
uniprot id: A0A3P9BAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101481470
gene id: 106582:LOC101481470
uniprot id: A0A3P9C7D9
uniprot id: A0A3P9C7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

106582:cpsf3
gene id: 106582:cpsf3
uniprot id: A0A3P9BER2
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101477961
gene id: 106582:LOC101477961
uniprot id: A0A3P9C7H1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

106582:fads6
gene id: 106582:fads6
uniprot id: A0A3P9BR60
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

106582:LOC101473643
gene id: 106582:LOC101473643
uniprot id: A0A3P9C370
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101479570
gene id: 106582:LOC101479570
uniprot id: A0A3P9C2I1
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101476515
gene id: 106582:LOC101476515
uniprot id: A0A3P9BHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

106582:vrtn
gene id: 106582:vrtn
uniprot id: A0A3P9C2W2
names: Similarity
messages: Belongs to the vertnin family.

106582:ctnnbip1
gene id: 106582:ctnnbip1
uniprot id: A0A3P9C6B4
names: Similarity
messages: Belongs to the CTNNBIP1 family.

106582:LOC101468997
gene id: 106582:LOC101468997
uniprot id: A0A3P9B5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

106582:LOC101480787
gene id: 106582:LOC101480787
uniprot id: A0A3P9D0I3
names: Similarity
messages: Belongs to the SNF7 family.

106582:LOC101487558
gene id: 106582:LOC101487558
uniprot id: A0A3P9D9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

106582:LOC101484025
gene id: 106582:LOC101484025
uniprot id: A0A3P9DLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

106582:LOC101464072
gene id: 106582:LOC101464072
uniprot id: A0A3P9B676
names: Similarity
messages: Belongs to the heme oxygenase family.

106582:LOC101473803
gene id: 106582:LOC101473803
uniprot id: A0A3P9ATM0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

106582:serinc5
gene id: 106582:serinc5
uniprot id: A0A3P9CLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101476944
gene id: 106582:LOC101476944
uniprot id: A0A3P9DIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:kif1bp
gene id: 106582:kif1bp
uniprot id: A0A3P9C025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

106582:LOC101479549
gene id: 106582:LOC101479549
uniprot id: A0A3P9BQ66
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101478356
gene id: 106582:LOC101478356
uniprot id: A0A3P9DIU6
names: Similarity
messages: Belongs to the angiomotin family.

106582:tshr
gene id: 106582:tshr
uniprot id: A0A3P9BE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

106582:gpat3
gene id: 106582:gpat3
uniprot id: A0A3P9DAQ5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:LOC101467939
gene id: 106582:LOC101467939
uniprot id: A0A3P9CQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

106582:map1lc3a
gene id: 106582:map1lc3a
uniprot id: A0A3P9BQE8
names: Similarity
messages: Belongs to the ATG8 family.

106582:tubgcp3
gene id: 106582:tubgcp3
uniprot id: A0A3P9BLB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

106582:rnf111
gene id: 106582:rnf111
uniprot id: A0A3P9C849
uniprot id: A0A3P9C978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

106582:ggt5
gene id: 106582:ggt5
uniprot id: A0A3P9BAL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

106582:LOC101483872
gene id: 106582:LOC101483872
uniprot id: A0A3P9CRE8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101474241
gene id: 106582:LOC101474241
uniprot id: A0A3P9C1S1
names: Similarity
messages: Belongs to the RING-box family.

106582:rfx3
gene id: 106582:rfx3
uniprot id: A0A3P9CSY8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101486241
gene id: 106582:LOC101486241
uniprot id: A0A3P9C890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

106582:LOC101480388
gene id: 106582:LOC101480388
uniprot id: A0A3P9DSA1
names: Similarity
messages: Belongs to the NifU family.

106582:mtmr7
gene id: 106582:mtmr7
uniprot id: A0A3P9BF64
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

106582:gpcpd1
gene id: 106582:gpcpd1
uniprot id: A0A3P9BW94
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

106582:LOC101467289
gene id: 106582:LOC101467289
uniprot id: A0A3P9D951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

106582:prkca
gene id: 106582:prkca
uniprot id: A0A3P9AXE9
uniprot id: A0A3P9AY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

106582:fam171a2
gene id: 106582:fam171a2
uniprot id: A0A3P9BQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

106582:rnf13
gene id: 106582:rnf13
uniprot id: A0A3P9CNE9
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101474481
gene id: 106582:LOC101474481
uniprot id: A0A3P9DFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:LOC101483480
gene id: 106582:LOC101483480
uniprot id: A0A3P9D6E1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:ndfip1
gene id: 106582:ndfip1
uniprot id: A0A3P9B1N9
uniprot id: A0A3P9B1Q1
names: Subcellular Location Annotation
messages: Membrane

106582:nfasc
gene id: 106582:nfasc
uniprot id: A0A3P9BBE1
uniprot id: A0A3P9BBJ0
uniprot id: A0A3P9BBM6
uniprot id: A0A3P9BBR8
uniprot id: A0A3P9BBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

106582:LOC101474924
gene id: 106582:LOC101474924
uniprot id: A0A3P9AU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

106582:ruvbl1
gene id: 106582:ruvbl1
uniprot id: A0A3P9BR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

106582:LOC101481524
gene id: 106582:LOC101481524
uniprot id: A0A3P9AZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

106582:llph
gene id: 106582:llph
uniprot id: A0A3P9B2U2
names: Similarity
messages: Belongs to the learning-associated protein family.

106582:gtf2e1
gene id: 106582:gtf2e1
uniprot id: A0A3P9B076
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

106582:alad
gene id: 106582:alad
uniprot id: A0A3P9CCT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

106582:LOC101478188
gene id: 106582:LOC101478188
uniprot id: A0A3P9B8V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

106582:p4hb
gene id: 106582:p4hb
uniprot id: A0A3P9C1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

106582:LOC101487241
gene id: 106582:LOC101487241
uniprot id: A0A3P9BKI8
names: Similarity
messages: Belongs to the sorting nexin family.

106582:LOC101481486
gene id: 106582:LOC101481486
uniprot id: A0A3P9ASK9
names: Similarity
messages: Belongs to the MARCKS family.

106582:stk32a
gene id: 106582:stk32a
uniprot id: A0A3P9BNH4
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:elk4
gene id: 106582:elk4
uniprot id: A0A3P9BJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101470560
gene id: 106582:LOC101470560
uniprot id: A0A3P9AX03
uniprot id: A0A3P9AXJ2
uniprot id: A0A3P9AXK3
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:pcca
gene id: 106582:pcca
uniprot id: A0A3P9CRU5
names: Subcellular Location Annotation
messages: Mitochondrion matrix

106582:serinc1
gene id: 106582:serinc1
uniprot id: A0A3P9CBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

106582:LOC101481258
gene id: 106582:LOC101481258
uniprot id: A0A3P9DFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

106582:tmem233
gene id: 106582:tmem233
uniprot id: A0A3P9DMM0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

106582:LOC101468855
gene id: 106582:LOC101468855
uniprot id: A0A3P9C7X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

106582:LOC101481302
gene id: 106582:LOC101481302
uniprot id: A0A3P9B780
names: Subcellular Location Annotation
messages: Membrane

106582:dnajc25
gene id: 106582:dnajc25
uniprot id: A0A3P9ARR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

106582:akirin1
gene id: 106582:akirin1
uniprot id: A0A3P9BLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

106582:LOC101485572
gene id: 106582:LOC101485572
uniprot id: A0A3P9BMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

106582:dapk2
gene id: 106582:dapk2
uniprot id: A0A3P9D7V7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101473742
gene id: 106582:LOC101473742
uniprot id: A0A3P9C4Y4
names: Subcellular Location Annotation
messages: extracellular space

106582:ints3
gene id: 106582:ints3
uniprot id: A0A3P9C3B5
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

106582:ckb
gene id: 106582:ckb
uniprot id: A0A3P9AXN3
uniprot id: A0A3P9AYD2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

106582:wdr24
gene id: 106582:wdr24
uniprot id: A0A3P9BZ83
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

106582:LOC101476853
gene id: 106582:LOC101476853
uniprot id: A0A3P9BQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:zic5
gene id: 106582:zic5
uniprot id: A0A3P9D305
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

106582:aprt
gene id: 106582:aprt
uniprot id: A0A3P9CR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

106582:LOC101486490
gene id: 106582:LOC101486490
uniprot id: A0A3P9CJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

106582:ace2
gene id: 106582:ace2
uniprot id: A0A3P9BEA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

106582:dld
gene id: 106582:dld
uniprot id: A0A3P9CH84
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

106582:fam206a
gene id: 106582:fam206a
uniprot id: A0A3P9BF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

106582:LOC101465839
gene id: 106582:LOC101465839
uniprot id: A0A3P9CA64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:nkx2-8
gene id: 106582:nkx2-8
uniprot id: A0A3P9CC71
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473615
gene id: 106582:LOC101473615
uniprot id: A0A3P9CQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

106582:LOC101483810
gene id: 106582:LOC101483810
uniprot id: A0A3P9CT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

106582:isyna1
gene id: 106582:isyna1
uniprot id: A0A3P9AT53
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

106582:mtmr3
gene id: 106582:mtmr3
uniprot id: A0A3P9B0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

106582:LOC101487162
gene id: 106582:LOC101487162
uniprot id: A0A3P9CY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

106582:LOC101486675
gene id: 106582:LOC101486675
uniprot id: A0A3P9CM20
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

106582:hgf
gene id: 106582:hgf
uniprot id: A0A3P9CXJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
messages: extracellular space

106582:hmces
gene id: 106582:hmces
uniprot id: A0A3P9BX76
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

106582:svbp
gene id: 106582:svbp
uniprot id: A0A3P9BKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

106582:LOC101474488
gene id: 106582:LOC101474488
uniprot id: A0A3P9CTR4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

106582:srpra
gene id: 106582:srpra
uniprot id: A0A3P9C6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

106582:btg1
gene id: 106582:btg1
uniprot id: A0A3P9BB56
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

106582:LOC101478871
gene id: 106582:LOC101478871
uniprot id: A0A3P9AX53
names: Similarity
messages: Belongs to the CCDC149 family.

106582:kcmf1
gene id: 106582:kcmf1
uniprot id: A0A3P9AT43
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

106582:adgrl2
gene id: 106582:adgrl2
uniprot id: A0A3P9DJB9
uniprot id: A0A3P9DJZ7
names: Subcellular Location Annotation
messages: Membrane

106582:snupn
gene id: 106582:snupn
uniprot id: A0A3P9BWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

106582:nudt21
gene id: 106582:nudt21
uniprot id: A0A3P9C6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

106582:LOC101488007
gene id: 106582:LOC101488007
uniprot id: A0A3P9B1N2
names: Similarity
messages: Belongs to the beta-catenin family.

106582:LOC101473085
gene id: 106582:LOC101473085
uniprot id: A0A3P9C591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

106582:LOC101487870
gene id: 106582:LOC101487870
uniprot id: A0A3P9CP78
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

106582:LOC101471700
gene id: 106582:LOC101471700
uniprot id: A0A3P9C6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

106582:exosc1
gene id: 106582:exosc1
uniprot id: A0A3P9BHC4
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101485738
gene id: 106582:LOC101485738
uniprot id: A0A3P9AVW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106582:LOC101471323
gene id: 106582:LOC101471323
uniprot id: A0A3P9BJA3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

106582:stx18
gene id: 106582:stx18
uniprot id: A0A3P9DNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

106582:LOC101478030
gene id: 106582:LOC101478030
uniprot id: A0A3P9CPI5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

106582:fermt1
gene id: 106582:fermt1
uniprot id: A0A3P9BWE7
names: Similarity
messages: Belongs to the kindlin family.

106582:gata3
gene id: 106582:gata3
uniprot id: A0A3P9D3A0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482945
gene id: 106582:LOC101482945
uniprot id: A0A3P9B4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

106582:cdh22
gene id: 106582:cdh22
uniprot id: A0A3P9BA91
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:p2rx5
gene id: 106582:p2rx5
uniprot id: A0A3P9ARL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

106582:trappc11
gene id: 106582:trappc11
uniprot id: A0A3P9CNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

106582:LOC101485832
gene id: 106582:LOC101485832
uniprot id: A0A3P9C2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101469075
gene id: 106582:LOC101469075
uniprot id: A0A3P9B555
names: Subcellular Location Annotation
messages: Membrane

106582:egfl6
gene id: 106582:egfl6
uniprot id: A0A3P9B002
uniprot id: A0A3P9B003
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:slc31a1
gene id: 106582:slc31a1
uniprot id: A0A3P9D8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

106582:vps37b
gene id: 106582:vps37b
uniprot id: A0A3P9B8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

106582:dap3
gene id: 106582:dap3
uniprot id: A0A3P9CFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

106582:p2rx7
gene id: 106582:p2rx7
uniprot id: A0A3P9CY30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

106582:LOC101468516
gene id: 106582:LOC101468516
uniprot id: A0A3P9ARB5
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:uck1
gene id: 106582:uck1
uniprot id: A0A3P9B1A7
names: Similarity
messages: Belongs to the uridine kinase family.

106582:LOC101480700
gene id: 106582:LOC101480700
uniprot id: A0A3P9D9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

106582:hip1r
gene id: 106582:hip1r
uniprot id: A0A3P9AUK0
uniprot id: A0A3P9AUL1
names: Similarity
messages: Belongs to the SLA2 family.

106582:slc7a6
gene id: 106582:slc7a6
uniprot id: A0A3P9B5B1
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101487770
gene id: 106582:LOC101487770
uniprot id: A0A3P9CAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

106582:bckdha
gene id: 106582:bckdha
uniprot id: A0A3P9DEA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

106582:sf1
gene id: 106582:sf1
uniprot id: A0A3P9BQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

106582:znf706
gene id: 106582:znf706
uniprot id: A0A3P9DIK9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:LOC101469907
gene id: 106582:LOC101469907
uniprot id: A0A3P9DLP9
uniprot id: A0A3P9DM21
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

106582:fam214b
gene id: 106582:fam214b
uniprot id: A0A3P9C4V5
names: Similarity
messages: Belongs to the FAM214 family.

106582:LOC101482567
gene id: 106582:LOC101482567
uniprot id: A0A3P9BW65
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

106582:LOC101471187
gene id: 106582:LOC101471187
uniprot id: A0A3P9D879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

106582:LOC101486671
gene id: 106582:LOC101486671
uniprot id: A0A3P9B9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

106582:snx7
gene id: 106582:snx7
uniprot id: A0A3P9DA38
names: Similarity
messages: Belongs to the sorting nexin family.

106582:oxr1
gene id: 106582:oxr1
uniprot id: A0A3P9C2P7
uniprot id: A0A3P9C2U4
uniprot id: A0A3P9C3S8
names: Similarity
messages: Belongs to the OXR1 family.

106582:LOC101474871
gene id: 106582:LOC101474871
uniprot id: A0A3P9BBN7
names: Subcellular Location Annotation
messages: cytoskeleton

106582:LOC101483038
gene id: 106582:LOC101483038
uniprot id: A0A3P9BC24
names: Subcellular Location Annotation
messages: Nucleus

106582:acer1
gene id: 106582:acer1
uniprot id: A0A3P9CTV9
uniprot id: A0A3P9CUK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101480016
gene id: 106582:LOC101480016
uniprot id: A0A3P9B4C8
uniprot id: A0A3P9B4F4
names: Similarity
messages: Belongs to the ABI family.

106582:mrpl22
gene id: 106582:mrpl22
uniprot id: A0A3P9C145
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

106582:serpini1
gene id: 106582:serpini1
uniprot id: A0A3P9BY81
names: Similarity
messages: Belongs to the serpin family.

106582:LOC101463620
gene id: 106582:LOC101463620
uniprot id: A0A3P9CIN0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

106582:slc25a33
gene id: 106582:slc25a33
uniprot id: A0A3P9BHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101479483
gene id: 106582:LOC101479483
uniprot id: A0A3P9DB42
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101466930
gene id: 106582:LOC101466930
uniprot id: A0A3P9CHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:rrp7a
gene id: 106582:rrp7a
uniprot id: A0A3P9B9Y9
names: Similarity
messages: Belongs to the RRP7 family.

106582:comt
gene id: 106582:comt
uniprot id: A0A3P9BVN1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

106582:mut
gene id: 106582:mut
uniprot id: A0A3P9BVR3
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

106582:LOC101481450
gene id: 106582:LOC101481450
uniprot id: A0A3P9AWT4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

106582:chst7
gene id: 106582:chst7
uniprot id: A0A3P9D0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:LOC101469722
gene id: 106582:LOC101469722
uniprot id: A0A3P9BZX9
names: Subcellular Location Annotation
messages: Membrane

106582:pacsin2
gene id: 106582:pacsin2
uniprot id: A0A3P9B935
uniprot id: A0A3P9B974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Recycling endosome membrane
messages: caveola
messages: ruffle membrane

106582:smpdl3a
gene id: 106582:smpdl3a
uniprot id: A0A3P9BEU0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

106582:LOC101471840
gene id: 106582:LOC101471840
uniprot id: A0A3P9BYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

106582:cadm4
gene id: 106582:cadm4
uniprot id: A0A3P9B504
uniprot id: A0A3P9B530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

106582:atp10d
gene id: 106582:atp10d
uniprot id: A0A3P9CLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

106582:LOC101805557
gene id: 106582:LOC101805557
uniprot id: A0A3P9DCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

106582:tmem106a
gene id: 106582:tmem106a
uniprot id: A0A3P9BII3
names: Similarity
messages: Belongs to the TMEM106 family.

106582:ssrp1
gene id: 106582:ssrp1
uniprot id: A0A3P9B2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

106582:ube4b
gene id: 106582:ube4b
uniprot id: A0A3P9C6V3
uniprot id: A0A3P9C7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

106582:alox5
gene id: 106582:alox5
uniprot id: A0A3P9DSB7
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101482292
gene id: 106582:LOC101482292
uniprot id: A0A3P9DDK7
names: Subcellular Location Annotation
messages: Nucleus

106582:lg16h2orf49
gene id: 106582:lg16h2orf49
uniprot id: A0A3P9D6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

106582:bpnt1
gene id: 106582:bpnt1
uniprot id: A0A3P9AZJ9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

106582:med22
gene id: 106582:med22
uniprot id: A0A3P9C2C5
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

106582:polr3f
gene id: 106582:polr3f
uniprot id: A0A3P9CD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

106582:LOC101486497
gene id: 106582:LOC101486497
uniprot id: A0A3P9CU30
names: Similarity
messages: Belongs to the popeye family.

106582:LOC101478825
gene id: 106582:LOC101478825
uniprot id: A0A3P9DHJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC106676370
gene id: 106582:LOC106676370
uniprot id: A0A3P9DB32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

106582:LOC101470353
gene id: 106582:LOC101470353
uniprot id: A0A3P9BV27
names: Similarity
messages: Belongs to the aldo/keto reductase family.

106582:hmgcl
gene id: 106582:hmgcl
uniprot id: A0A3P9BDI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

106582:LOC101481811
gene id: 106582:LOC101481811
uniprot id: A0A3P9BBJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

106582:skap1
gene id: 106582:skap1
uniprot id: A0A3P9BLN7
names: Similarity
messages: Belongs to the SKAP family.

106582:trip12
gene id: 106582:trip12
uniprot id: A0A3P9BNZ3
uniprot id: A0A3P9BP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

106582:slc17a5
gene id: 106582:slc17a5
uniprot id: A0A3P9DPI5
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101465883
gene id: 106582:LOC101465883
uniprot id: A0A3P9BZ40
uniprot id: A0A3P9C039
names: Similarity
messages: Belongs to the UPF0488 family.

106582:LOC101466133
gene id: 106582:LOC101466133
uniprot id: A0A3P9ATD2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:LOC101477640
gene id: 106582:LOC101477640
uniprot id: A0A3P9CUJ9
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

106582:slc35b1
gene id: 106582:slc35b1
uniprot id: A0A3P9D9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

106582:pqlc2l
gene id: 106582:pqlc2l
uniprot id: A0A3P9BXM8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101476780
gene id: 106582:LOC101476780
uniprot id: A0A3P9BXI5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

106582:sf3b1
gene id: 106582:sf3b1
uniprot id: A0A3P9D322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

106582:barhl2
gene id: 106582:barhl2
uniprot id: A0A3P9BSQ0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101488043
gene id: 106582:LOC101488043
uniprot id: A0A3P9DHQ6
uniprot id: A0A3P9DHU2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

106582:arhgef6
gene id: 106582:arhgef6
uniprot id: A0A3P9BF36
uniprot id: A0A3P9BF63
names: Subcellular Location Annotation
messages: lamellipodium

106582:LOC101478532
gene id: 106582:LOC101478532
uniprot id: A0A3P9BNG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:fto
gene id: 106582:fto
uniprot id: A0A3P9BG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

106582:nprl2
gene id: 106582:nprl2
uniprot id: A0A3P9CBF8
names: Similarity
messages: Belongs to the NPR2 family.

106582:ube2h
gene id: 106582:ube2h
uniprot id: A0A3P9BHN4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:LOC101476507
gene id: 106582:LOC101476507
uniprot id: A0A3P9CT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

106582:LOC101467715
gene id: 106582:LOC101467715
uniprot id: A0A3P9DQB8
names: Similarity
messages: Belongs to the peptidase C48 family.

106582:clcn5
gene id: 106582:clcn5
uniprot id: A0A3P9CYD2
uniprot id: A0A3P9CYV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:skp1
gene id: 106582:skp1
uniprot id: A0A3P9BPC3
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

106582:LOC101473405
gene id: 106582:LOC101473405
uniprot id: A0A3P9CMA2
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

106582:LOC101473367
gene id: 106582:LOC101473367
uniprot id: A0A3P9CV05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

106582:fam83h
gene id: 106582:fam83h
uniprot id: A0A3P9B7M9
names: Similarity
messages: Belongs to the FAM83 family.

106582:tcp11l2
gene id: 106582:tcp11l2
uniprot id: A0A3P9BAH3
names: Similarity
messages: Belongs to the TCP11 family.

106582:irf8
gene id: 106582:irf8
uniprot id: A0A3P9C3I4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:LOC101466670
gene id: 106582:LOC101466670
uniprot id: A0A3P9BUC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101469491
gene id: 106582:LOC101469491
uniprot id: A0A3P9BDQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101485794
gene id: 106582:LOC101485794
uniprot id: A0A3P9BZX5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

106582:LOC101466532
gene id: 106582:LOC101466532
uniprot id: A0A3P9B6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

106582:parp1
gene id: 106582:parp1
uniprot id: A0A3P9CJV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

106582:LOC101487708
gene id: 106582:LOC101487708
uniprot id: A0A3P9B946
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:LOC101470708
gene id: 106582:LOC101470708
uniprot id: A0A3P9D996
names: Similarity
messages: Belongs to the oligoribonuclease family.

106582:LOC101468393
gene id: 106582:LOC101468393
uniprot id: A0A3P9D8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

106582:LOC101464568
gene id: 106582:LOC101464568
uniprot id: A0A3P9C8Q1
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

106582:nfx1
gene id: 106582:nfx1
uniprot id: A0A3P9CQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

106582:lrrc8d
gene id: 106582:lrrc8d
uniprot id: A0A3P9B8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

106582:LOC101484050
gene id: 106582:LOC101484050
uniprot id: A0A3P9CCW2
names: Similarity
messages: Belongs to the MAGUK family.

106582:rfc2
gene id: 106582:rfc2
uniprot id: A0A3P9DPL6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

106582:LOC101471450
gene id: 106582:LOC101471450
uniprot id: A0A3P9AZA8
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

106582:LOC101478649
gene id: 106582:LOC101478649
uniprot id: A0A3P9C8V9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:chst3
gene id: 106582:chst3
uniprot id: A0A3P9AUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

106582:LOC101465736
gene id: 106582:LOC101465736
uniprot id: A0A3P9DNH8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101483400
gene id: 106582:LOC101483400
uniprot id: A0A3P9C690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

106582:idua
gene id: 106582:idua
uniprot id: A0A3P9CS80
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

106582:LOC101479289
gene id: 106582:LOC101479289
uniprot id: A0A3P9B5Q7
names: Subcellular Location Annotation
messages: Membrane

106582:ndufs6
gene id: 106582:ndufs6
uniprot id: A0A3P9ARH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

106582:sept6
gene id: 106582:sept6
uniprot id: A0A3P9BKV6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

106582:LOC101476589
gene id: 106582:LOC101476589
uniprot id: A0A3P9DLC7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

106582:ankh
gene id: 106582:ankh
uniprot id: A0A3P9CR47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

106582:LOC101477724
gene id: 106582:LOC101477724
uniprot id: A0A3P9CLI4
names: Subcellular Location Annotation
messages: Membrane

106582:parp3
gene id: 106582:parp3
uniprot id: A0A3P9BVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

106582:pik3r1
gene id: 106582:pik3r1
uniprot id: A0A3P9BCI9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

106582:med28
gene id: 106582:med28
uniprot id: A0A3P9BM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

106582:LOC101468502
gene id: 106582:LOC101468502
uniprot id: A0A3P9AU80
names: Similarity
messages: Belongs to the CutC family.

106582:LOC101485033
gene id: 106582:LOC101485033
uniprot id: A0A3P9BR21
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

106582:APK84 gp12
gene id: 106582:APK84_gp12
uniprot id: Q2QES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101484468
gene id: 106582:LOC101484468
uniprot id: A0A3P9BRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

106582:tfap2e
gene id: 106582:tfap2e
uniprot id: A0A3P9DM18
names: Similarity
messages: Belongs to the AP-2 family.

106582:LOC101473251
gene id: 106582:LOC101473251
uniprot id: A0A3P9CXU1
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101463917
gene id: 106582:LOC101463917
uniprot id: A0A3P9AWT6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101475823
gene id: 106582:LOC101475823
uniprot id: A0A3P9BFN7
names: Similarity
messages: Belongs to the beta-catenin family.

106582:LOC101484439
gene id: 106582:LOC101484439
uniprot id: A0A3P9BUB6
names: Similarity
messages: Belongs to the DEAD box helicase family.

106582:triqk
gene id: 106582:triqk
uniprot id: A0A3P9BA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:grm2
gene id: 106582:grm2
uniprot id: A0A3P9BVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

106582:exosc9
gene id: 106582:exosc9
uniprot id: A0A3P9BZJ5
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101472628
gene id: 106582:LOC101472628
uniprot id: A0A3P9CL09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

106582:LOC101475404
gene id: 106582:LOC101475404
uniprot id: A0A3P9BLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

106582:snap47
gene id: 106582:snap47
uniprot id: A0A3P9DGG4
names: Similarity
messages: Belongs to the SVAP1 family.

106582:asphd2
gene id: 106582:asphd2
uniprot id: A0A3P9AST9
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

106582:tppp3
gene id: 106582:tppp3
uniprot id: A0A3P9AVP4
names: Similarity
messages: Belongs to the TPPP family.

106582:LOC101486450
gene id: 106582:LOC101486450
uniprot id: A0A3P9DBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

106582:degs1
gene id: 106582:degs1
uniprot id: A0A3P9CR50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

106582:LOC101480249
gene id: 106582:LOC101480249
uniprot id: A0A3P9CJC1
names: Similarity
messages: Belongs to the peptidase C1 family.

106582:LOC101485474
gene id: 106582:LOC101485474
uniprot id: A0A3P9BTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

106582:LOC101481868
gene id: 106582:LOC101481868
uniprot id: A0A3P9BZ17
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101466354
gene id: 106582:LOC101466354
uniprot id: A0A3P9AVB4
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

106582:me2
gene id: 106582:me2
uniprot id: A0A3P9BCI2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

106582:LOC101486225
gene id: 106582:LOC101486225
uniprot id: A0A3P9BJN2
names: Subcellular Location Annotation
messages: Membrane

106582:tatdn3
gene id: 106582:tatdn3
uniprot id: A0A3P9C3C4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

106582:galnt12
gene id: 106582:galnt12
uniprot id: A0A3P9BEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101479351
gene id: 106582:LOC101479351
uniprot id: A0A3P9DDW4
uniprot id: A0A3P9DDW9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

106582:LOC101472863
gene id: 106582:LOC101472863
uniprot id: A0A3P9BDL3
names: Similarity
messages: Belongs to the DDIT4 family.

106582:LOC101468982
gene id: 106582:LOC101468982
uniprot id: A0A3P9DR92
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

106582:fis1
gene id: 106582:fis1
uniprot id: A0A3P9D2B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

106582:LOC101479181
gene id: 106582:LOC101479181
uniprot id: A0A3P9BMC1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

106582:lztfl1
gene id: 106582:lztfl1
uniprot id: A0A3P9CSB0
uniprot id: A0A3P9CSY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

106582:mbtps2
gene id: 106582:mbtps2
uniprot id: A0A3P9CVQ0
names: Similarity
messages: Belongs to the peptidase M50A family.

106582:clptm1
gene id: 106582:clptm1
uniprot id: A0A3P9CJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

106582:ap1m2
gene id: 106582:ap1m2
uniprot id: A0A3P9DBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

106582:tgfb2
gene id: 106582:tgfb2
uniprot id: A0A3P9DH87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

106582:pggt1b
gene id: 106582:pggt1b
uniprot id: A0A3P9B938
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

106582:LOC101485505
gene id: 106582:LOC101485505
uniprot id: A0A3P9B243
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

106582:LOC101475737
gene id: 106582:LOC101475737
uniprot id: A0A3P9D8S1
names: Similarity
messages: Belongs to the Bcl-2 family.

106582:LOC101475829
gene id: 106582:LOC101475829
uniprot id: A0A3P9DKV5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106582:mpp3
gene id: 106582:mpp3
uniprot id: A0A3P9D9S9
names: Similarity
messages: Belongs to the MAGUK family.

106582:LOC101478003
gene id: 106582:LOC101478003
uniprot id: A0A3P9DCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101476197
gene id: 106582:LOC101476197
uniprot id: A0A3P9C8Z3
names: Similarity
messages: Belongs to the intermediate filament family.

106582:mfsd14a
gene id: 106582:mfsd14a
uniprot id: A0A3P9DFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

106582:plekha8
gene id: 106582:plekha8
uniprot id: A0A3P9C8Z7
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

106582:LOC101467223
gene id: 106582:LOC101467223
uniprot id: A0A3P9B6V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:alx4
gene id: 106582:alx4
uniprot id: A0A3P9BAD6
names: Subcellular Location Annotation
messages: Nucleus

106582:ift57
gene id: 106582:ift57
uniprot id: A0A3P9CZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

106582:LOC101466533
gene id: 106582:LOC101466533
uniprot id: A0A3P9BKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

106582:lg15h6orf58
gene id: 106582:lg15h6orf58
uniprot id: A0A3P9C4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

106582:itfg1
gene id: 106582:itfg1
uniprot id: A0A3P9B6P9
names: Similarity
messages: Belongs to the TIP family.

106582:LOC101484231
gene id: 106582:LOC101484231
uniprot id: A0A3P9BN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

106582:impad1
gene id: 106582:impad1
uniprot id: A0A3P9CD53
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

106582:hal
gene id: 106582:hal
uniprot id: A0A3P9BFZ6
names: Similarity
messages: Belongs to the PAL/histidase family.

106582:rpl13a
gene id: 106582:rpl13a
uniprot id: A0A3P9B987
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

106582:tmem183a
gene id: 106582:tmem183a
uniprot id: A0A3P9ASQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

106582:LOC101473100
gene id: 106582:LOC101473100
uniprot id: A0A3P9CKQ8
uniprot id: A0A3P9CKT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101479880
gene id: 106582:LOC101479880
uniprot id: A0A3P9C4K6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

106582:LOC101471919
gene id: 106582:LOC101471919
uniprot id: A0A3P9CET3
names: Similarity
messages: Belongs to the ATG8 family.

106582:LOC101480165
gene id: 106582:LOC101480165
uniprot id: A0A3P9C8G3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101473948
gene id: 106582:LOC101473948
uniprot id: A0A3P9CFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101485437
gene id: 106582:LOC101485437
uniprot id: A0A3P9CUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

106582:tacr2
gene id: 106582:tacr2
uniprot id: A0A3P9BZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101485390
gene id: 106582:LOC101485390
uniprot id: A0A3P9B6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

106582:LOC101480075
gene id: 106582:LOC101480075
uniprot id: A0A3P9AYX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

106582:grhl1
gene id: 106582:grhl1
uniprot id: A0A3P9BET3
names: Subcellular Location Annotation
messages: Nucleus

106582:cd63
gene id: 106582:cd63
uniprot id: A0A3P9DM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

106582:LOC101464305
gene id: 106582:LOC101464305
uniprot id: A0A3P9DKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:fignl1
gene id: 106582:fignl1
uniprot id: A0A3P9C0X3
names: Similarity
messages: Belongs to the AAA ATPase family.

106582:LOC101486495
gene id: 106582:LOC101486495
uniprot id: A0A3P9DJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

106582:lsm5
gene id: 106582:lsm5
uniprot id: A0A3P9CVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

106582:plpp3
gene id: 106582:plpp3
uniprot id: A0A3P9CW42
uniprot id: A0A3P9CWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

106582:rhbdl1
gene id: 106582:rhbdl1
uniprot id: A0A3P9BZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

106582:LOC101486440
gene id: 106582:LOC101486440
uniprot id: A0A3P9CVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

106582:LOC101474342
gene id: 106582:LOC101474342
uniprot id: A0A3P9CPU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

106582:mrps12
gene id: 106582:mrps12
uniprot id: A0A3P9CLC5
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

106582:LOC101478346
gene id: 106582:LOC101478346
uniprot id: A0A3P9CS14
uniprot id: A0A3P9CSS9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

106582:kcne2
gene id: 106582:kcne2
uniprot id: A0A3P9AY39
names: Similarity
messages: Belongs to the potassium channel KCNE family.

106582:LOC101483036
gene id: 106582:LOC101483036
uniprot id: A0A3P9B046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

106582:LOC101478569
gene id: 106582:LOC101478569
uniprot id: A0A3P9CXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

106582:LOC101487537
gene id: 106582:LOC101487537
uniprot id: A0A3P9DL44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

106582:eif4e3
gene id: 106582:eif4e3
uniprot id: A0A3P9BP50
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

106582:LOC101481446
gene id: 106582:LOC101481446
uniprot id: A0A3P9B0N7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:psme4
gene id: 106582:psme4
uniprot id: A0A3P9BDY1
uniprot id: A0A3P9BE49
names: Similarity
messages: Belongs to the BLM10 family.

106582:actr8
gene id: 106582:actr8
uniprot id: A0A3P9D1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

106582:psmc3ip
gene id: 106582:psmc3ip
uniprot id: A0A3P9D712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

106582:LOC101479184
gene id: 106582:LOC101479184
uniprot id: A0A3P9AR71
names: Similarity
messages: Belongs to the GADD45 family.

106582:lg4h16orf72
gene id: 106582:lg4h16orf72
uniprot id: A0A3P9BJT8
names: Similarity
messages: Belongs to the TAPR1 family.

106582:cers5
gene id: 106582:cers5
uniprot id: A0A3P9B640
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

106582:canx
gene id: 106582:canx
uniprot id: A0A3P9B5P8
names: Similarity
messages: Belongs to the calreticulin family.

106582:tbx1
gene id: 106582:tbx1
uniprot id: A0A3P9AUA3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:pde6c
gene id: 106582:pde6c
uniprot id: A0A3P9CD61
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:tfip11
gene id: 106582:tfip11
uniprot id: A0A3P9CJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

106582:LOC101464643
gene id: 106582:LOC101464643
uniprot id: A0A3P9CLA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

106582:LOC101482734
gene id: 106582:LOC101482734
uniprot id: A0A3P9D845
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101467623
gene id: 106582:LOC101467623
uniprot id: A0A3P9BJ20
names: Similarity
messages: Belongs to the globin family.

106582:LOC101465118
gene id: 106582:LOC101465118
uniprot id: A0A3P9BBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

106582:LOC101469762
gene id: 106582:LOC101469762
uniprot id: A0A3P9CB33
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:sf3b4
gene id: 106582:sf3b4
uniprot id: A0A3P9DN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

106582:cdk6
gene id: 106582:cdk6
uniprot id: A0A3P9BLH5
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101481190
gene id: 106582:LOC101481190
uniprot id: A0A3P9B0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-III AFP family.
messages: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
messages: Secreted

106582:prpf38a
gene id: 106582:prpf38a
uniprot id: A0A3P9CNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

106582:LOC106674458
gene id: 106582:LOC106674458
uniprot id: A0A3P9D5Y3
names: Similarity
messages: Belongs to the globin family.

106582:srsf5
gene id: 106582:srsf5
uniprot id: A0A3P9BVD9
names: Similarity
messages: Belongs to the splicing factor SR family.

106582:ercc2
gene id: 106582:ercc2
uniprot id: A0A3P9DDQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

106582:LOC101479984
gene id: 106582:LOC101479984
uniprot id: A0A3P9B311
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

106582:plcg2
gene id: 106582:plcg2
uniprot id: A0A3P9AQW8
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

106582:LOC101478527
gene id: 106582:LOC101478527
uniprot id: A0A3P9BNK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:kif3a
gene id: 106582:kif3a
uniprot id: A0A3P9BZU9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

106582:ctbs
gene id: 106582:ctbs
uniprot id: A0A3P9ASI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

106582:tlcd2
gene id: 106582:tlcd2
uniprot id: A0A3P9CE39
names: Subcellular Location Annotation
messages: Membrane

106582:alg9
gene id: 106582:alg9
uniprot id: A0A3P9CTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101471232
gene id: 106582:LOC101471232
uniprot id: A0A3P9BGN9
names: Similarity
messages: Belongs to the FXYD family.

106582:lg7h11orf49
gene id: 106582:lg7h11orf49
uniprot id: A0A3P9D8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

106582:tsn
gene id: 106582:tsn
uniprot id: A0A3P9CRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

106582:sec11a
gene id: 106582:sec11a
uniprot id: A0A3P9BQN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:ptprz1
gene id: 106582:ptprz1
uniprot id: A0A3P9CD43
uniprot id: A0A3P9CDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

106582:LOC101481805
gene id: 106582:LOC101481805
uniprot id: A0A3P9DMN3
names: Subcellular Location Annotation
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

106582:LOC101486312
gene id: 106582:LOC101486312
uniprot id: A0A3P9DQL6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101481621
gene id: 106582:LOC101481621
uniprot id: A0A3P9D055
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101478360
gene id: 106582:LOC101478360
uniprot id: A0A3P9BDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

106582:ephx1
gene id: 106582:ephx1
uniprot id: A0A3P9CE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

106582:stx5
gene id: 106582:stx5
uniprot id: A0A3P9B9G0
uniprot id: A0A3P9B9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

106582:atad2b
gene id: 106582:atad2b
uniprot id: A0A3P9BWX9
names: Similarity
messages: Belongs to the AAA ATPase family.

106582:brinp3
gene id: 106582:brinp3
uniprot id: A0A3P9CFK2
names: Similarity
messages: Belongs to the BRINP family.

106582:mpv17l2
gene id: 106582:mpv17l2
uniprot id: A0A3P9CI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

106582:lef1
gene id: 106582:lef1
uniprot id: A0A3P9CV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

106582:LOC101486459
gene id: 106582:LOC101486459
uniprot id: A0A3P9C4F4
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

106582:phox2a
gene id: 106582:phox2a
uniprot id: A0A3P9BJ74
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101484446
gene id: 106582:LOC101484446
uniprot id: A0A3P9ATX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

106582:LOC101484578
gene id: 106582:LOC101484578
uniprot id: A0A3P9AZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

106582:dao
gene id: 106582:dao
uniprot id: A0A3P9CDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

106582:ltc4s
gene id: 106582:ltc4s
uniprot id: A0A3P9B5W4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101481694
gene id: 106582:LOC101481694
uniprot id: A0A3P9BI25
names: Similarity
messages: Belongs to the YY transcription factor family.

106582:LOC101479797
gene id: 106582:LOC101479797
uniprot id: A0A3P9BQ87
names: Similarity
messages: Belongs to the MAGUK family.

106582:rprd1b
gene id: 106582:rprd1b
uniprot id: A0A3P9CYW0
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

106582:znf711
gene id: 106582:znf711
uniprot id: A0A3P9BYK1
names: Subcellular Location Annotation
messages: Nucleus

106582:ppm1g
gene id: 106582:ppm1g
uniprot id: A0A3P9BY32
names: Similarity
messages: Belongs to the PP2C family.

106582:atf4
gene id: 106582:atf4
uniprot id: A0A3P9BE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

106582:ccz1
gene id: 106582:ccz1
uniprot id: A0A3P9BNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

106582:xpnpep1
gene id: 106582:xpnpep1
uniprot id: A0A3P9B479
uniprot id: A0A3P9B488
uniprot id: A0A3P9B4B7
names: Similarity
messages: Belongs to the peptidase M24B family.

106582:LOC101472464
gene id: 106582:LOC101472464
uniprot id: A0A3P9ARJ7
uniprot id: A0A3P9ARS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

106582:LOC101477807
gene id: 106582:LOC101477807
uniprot id: A0A3P9DNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

106582:LOC101484649
gene id: 106582:LOC101484649
uniprot id: A0A3P9C516
names: Subcellular Location Annotation
messages: Nucleus

106582:pcsk5
gene id: 106582:pcsk5
uniprot id: A0A3P9AW66
names: Similarity
messages: Belongs to the peptidase S8 family.

106582:ubac2
gene id: 106582:ubac2
uniprot id: A0A3P9DPX6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101469002
gene id: 106582:LOC101469002
uniprot id: A0A3P9BXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

106582:exoc1
gene id: 106582:exoc1
uniprot id: A0A3P9CXG8
names: Similarity
messages: Belongs to the SEC3 family.

106582:rhbdf2
gene id: 106582:rhbdf2
uniprot id: A0A3P9AUC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

106582:rps17
gene id: 106582:rps17
uniprot id: A0A3P9D7Q4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

106582:LOC101478598
gene id: 106582:LOC101478598
uniprot id: A0A3P9BQK6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

106582:LOC101478540
gene id: 106582:LOC101478540
uniprot id: A0A3P9CAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:retreg3
gene id: 106582:retreg3
uniprot id: A0A3P9D717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

106582:uhrf2
gene id: 106582:uhrf2
uniprot id: A0A3P9CSI6
names: Subcellular Location Annotation
messages: Nucleus

106582:phb
gene id: 106582:phb
uniprot id: A0A3P9D9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

106582:mipep
gene id: 106582:mipep
uniprot id: A0A3P9C506
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

106582:LOC101475611
gene id: 106582:LOC101475611
uniprot id: A0A3P9CJD4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101470348
gene id: 106582:LOC101470348
uniprot id: A0A3P9B2L2
uniprot id: A0A3P9B2M5
uniprot id: A0A3P9B2Q0
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

106582:dglucy
gene id: 106582:dglucy
uniprot id: A0A3P9B8C1
uniprot id: A0A3P9B8F7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

106582:LOC101487266
gene id: 106582:LOC101487266
uniprot id: A0A3P9CFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

106582:pemt
gene id: 106582:pemt
uniprot id: A0A3P9BG14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

106582:LOC101482018
gene id: 106582:LOC101482018
uniprot id: A0A3P9DKI9
names: Similarity
messages: Belongs to the mab-21 family.

106582:LOC101470683
gene id: 106582:LOC101470683
uniprot id: A0A3P9BNP1
names: Similarity
messages: Belongs to the GDNFR family.

106582:LOC101474418
gene id: 106582:LOC101474418
uniprot id: A0A3P9B6A6
uniprot id: A0A3P9B6J6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101486837
gene id: 106582:LOC101486837
uniprot id: A0A3P9CBW3
names: Similarity
messages: Belongs to the NipSnap family.

106582:utp6
gene id: 106582:utp6
uniprot id: A0A3P9DBZ2
names: Similarity
messages: Belongs to the UTP6 family.

106582:LOC101486527
gene id: 106582:LOC101486527
uniprot id: A0A3P9B3Q3
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

106582:cebpd
gene id: 106582:cebpd
uniprot id: A0A3P9DGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

106582:erbb4
gene id: 106582:erbb4
uniprot id: A0A3P9CCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

106582:LOC101466462
gene id: 106582:LOC101466462
uniprot id: A0A3P9B8D5
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

106582:scarf2
gene id: 106582:scarf2
uniprot id: A0A3P9CAN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:wars2
gene id: 106582:wars2
uniprot id: A0A3P9CV18
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:LOC101482854
gene id: 106582:LOC101482854
uniprot id: A0A3P9AS39
uniprot id: A0A3P9ASA9
uniprot id: A0A3P9ASX7
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

106582:LOC101475460
gene id: 106582:LOC101475460
uniprot id: A0A3P9BZ34
names: Subcellular Location Annotation
messages: Membrane

106582:nop56
gene id: 106582:nop56
uniprot id: A0A3P9DNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

106582:pappa
gene id: 106582:pappa
uniprot id: A0A3P9CWF2
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101468242
gene id: 106582:LOC101468242
uniprot id: A0A3P9BV84
uniprot id: A0A3P9BW09
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

106582:LOC101474500
gene id: 106582:LOC101474500
uniprot id: A0A3P9CXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

106582:kcnk10
gene id: 106582:kcnk10
uniprot id: A0A3P9B1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:spdya
gene id: 106582:spdya
uniprot id: A0A3P9BRB5
names: Similarity
messages: Belongs to the Speedy/Ringo family.

106582:LOC101472197
gene id: 106582:LOC101472197
uniprot id: A0A3P9CL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

106582:mixl1
gene id: 106582:mixl1
uniprot id: A0A3P9CK18
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101479257
gene id: 106582:LOC101479257
uniprot id: A0A3P9CXI8
names: Similarity
messages: Belongs to the OSBP family.

106582:panx3
gene id: 106582:panx3
uniprot id: A0A3P9DAX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

106582:LOC101481587
gene id: 106582:LOC101481587
uniprot id: A0A3P9CJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

106582:LOC101483828
gene id: 106582:LOC101483828
uniprot id: A0A3P9B4D1
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

106582:arf3
gene id: 106582:arf3
uniprot id: A0A3P9BPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

106582:tomm5
gene id: 106582:tomm5
uniprot id: A0A3P9C773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

106582:LOC101467901
gene id: 106582:LOC101467901
uniprot id: A0A3P9CJ96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101466528
gene id: 106582:LOC101466528
uniprot id: A0A3P9B123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:LOC101477761
gene id: 106582:LOC101477761
uniprot id: A0A3P9D7T0
names: Subcellular Location Annotation
messages: Nucleus

106582:mrm2
gene id: 106582:mrm2
uniprot id: A0A3P9D817
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

106582:LOC101469593
gene id: 106582:LOC101469593
uniprot id: A0A3P9AVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:polr1c
gene id: 106582:polr1c
uniprot id: A0A3P9CS37
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

106582:LOC101471311
gene id: 106582:LOC101471311
uniprot id: A0A3P9AWC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:ptpn4
gene id: 106582:ptpn4
uniprot id: A0A3P9AWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

106582:sema6a
gene id: 106582:sema6a
uniprot id: A0A3P9BPC7
uniprot id: A0A3P9BPE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:ptges3
gene id: 106582:ptges3
uniprot id: A0A3P9DKY8
names: Similarity
messages: Belongs to the p23/wos2 family.

106582:LOC101481844
gene id: 106582:LOC101481844
uniprot id: A0A3P9AWQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

106582:mycbp
gene id: 106582:mycbp
uniprot id: A0A3P9BM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

106582:LOC101485934
gene id: 106582:LOC101485934
uniprot id: A0A3P9BKW1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

106582:LOC101466512
gene id: 106582:LOC101466512
uniprot id: A0A3P9BX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

106582:LOC101469989
gene id: 106582:LOC101469989
uniprot id: A0A3P9CHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:lrig1
gene id: 106582:lrig1
uniprot id: A0A3P9C117
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101478422
gene id: 106582:LOC101478422
uniprot id: A0A3P9BEV3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

106582:LOC101471587
gene id: 106582:LOC101471587
uniprot id: A0A3P9BEF4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101471114
gene id: 106582:LOC101471114
uniprot id: A0A3P9B2A3
names: Similarity
messages: Belongs to the GADD45 family.

106582:LOC101472019
gene id: 106582:LOC101472019
uniprot id: A0A3P9DLS6
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

106582:edem1
gene id: 106582:edem1
uniprot id: A0A3P9CDN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

106582:slc35e3
gene id: 106582:slc35e3
uniprot id: A0A3P9D4B7
names: Subcellular Location Annotation
messages: Membrane

106582:trip13
gene id: 106582:trip13
uniprot id: A0A3P9CAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

106582:hlf
gene id: 106582:hlf
uniprot id: A0A3P9ASP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

106582:cfap36
gene id: 106582:cfap36
uniprot id: A0A3P9DPL4
uniprot id: A0A3P9DQH7
names: Similarity
messages: Belongs to the CFAP36 family.

106582:spry2
gene id: 106582:spry2
uniprot id: A0A3P9B7X3
names: Similarity
messages: Belongs to the sprouty family.

106582:LOC101472704
gene id: 106582:LOC101472704
uniprot id: A0A3P9DEJ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

106582:LOC101482211
gene id: 106582:LOC101482211
uniprot id: A0A3P9BHS1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:foxc1
gene id: 106582:foxc1
uniprot id: A0A3P9CK73
names: Subcellular Location Annotation
messages: Nucleus

106582:sh3gl1
gene id: 106582:sh3gl1
uniprot id: A0A3P9BCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

106582:LOC101484987
gene id: 106582:LOC101484987
uniprot id: A0A3P9BS48
names: Subcellular Location Annotation
messages: Nucleus

106582:mfsd8
gene id: 106582:mfsd8
uniprot id: A0A3P9AT79
names: Subcellular Location Annotation
messages: Membrane

106582:parn
gene id: 106582:parn
uniprot id: A0A3P9C7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

106582:ndufs7
gene id: 106582:ndufs7
uniprot id: A0A3P9CK65
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

106582:LOC101469595
gene id: 106582:LOC101469595
uniprot id: A0A3P9CRZ8
uniprot id: A0A3P9CS03
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101470082
gene id: 106582:LOC101470082
uniprot id: A0A3P9DMW8
names: Similarity
messages: Belongs to the intermediate filament family.

106582:LOC101464944
gene id: 106582:LOC101464944
uniprot id: A0A3P9CAS7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

106582:unk
gene id: 106582:unk
uniprot id: A0A3P9BCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

106582:LOC101470304
gene id: 106582:LOC101470304
uniprot id: A0A3P9ARG3
names: Similarity
messages: Belongs to the HEBP family.

106582:taf6
gene id: 106582:taf6
uniprot id: A0A3P9CIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

106582:LOC101480169
gene id: 106582:LOC101480169
uniprot id: A0A3P9B030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

106582:LOC101465704
gene id: 106582:LOC101465704
uniprot id: A0A3P9CA80
names: Subcellular Location Annotation
messages: Membrane

106582:cdadc1
gene id: 106582:cdadc1
uniprot id: A0A3P9BLM4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

106582:nsa2
gene id: 106582:nsa2
uniprot id: A0A3P9B766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

106582:LOC101468989
gene id: 106582:LOC101468989
uniprot id: A0A3P9ATV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

106582:rnf114
gene id: 106582:rnf114
uniprot id: A0A3P9DMA4
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

106582:LOC101465389
gene id: 106582:LOC101465389
uniprot id: A0A3P9CRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

106582:LOC101484608
gene id: 106582:LOC101484608
uniprot id: A0A3P9BNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:LOC101469345
gene id: 106582:LOC101469345
uniprot id: A0A3P9DL14
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101486817
gene id: 106582:LOC101486817
uniprot id: A0A3P9AYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

106582:timm17a
gene id: 106582:timm17a
uniprot id: A0A3P9BBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101482582
gene id: 106582:LOC101482582
uniprot id: A0A3P9C9B0
names: Similarity
messages: Belongs to the HEBP family.

106582:mri1
gene id: 106582:mri1
uniprot id: A0A3P9BJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

106582:naif1
gene id: 106582:naif1
uniprot id: A0A3P9AT98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

106582:api5
gene id: 106582:api5
uniprot id: A0A3P9C0J3
names: Similarity
messages: Belongs to the API5 family.

106582:slc25a44
gene id: 106582:slc25a44
uniprot id: A0A3P9C8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

106582:srf
gene id: 106582:srf
uniprot id: A0A3P9BV45
names: Subcellular Location Annotation
messages: Nucleus

106582:ndufs8
gene id: 106582:ndufs8
uniprot id: A0A3P9CDL2
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

106582:LOC101483902
gene id: 106582:LOC101483902
uniprot id: A0A3P9C922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

106582:slc12a1
gene id: 106582:slc12a1
uniprot id: A0A3P9C088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

106582:LOC101474082
gene id: 106582:LOC101474082
uniprot id: A0A3P9CJM4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

106582:rbm48
gene id: 106582:rbm48
uniprot id: A0A3P9BDX6
names: Similarity
messages: Belongs to the RBM48 family.

106582:LOC101482637
gene id: 106582:LOC101482637
uniprot id: A0A3P9AS97
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

106582:ipo7
gene id: 106582:ipo7
uniprot id: A0A3P9CCP4
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101473889
gene id: 106582:LOC101473889
uniprot id: A0A3P9AS87
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:cacng4
gene id: 106582:cacng4
uniprot id: A0A3P9AXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

106582:pex19
gene id: 106582:pex19
uniprot id: A0A3P9DCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

106582:LOC106676198
gene id: 106582:LOC106676198
uniprot id: A0A3P9BZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

106582:LOC101486112
gene id: 106582:LOC101486112
uniprot id: A0A3P9ASA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101475041
gene id: 106582:LOC101475041
uniprot id: A0A3P9DC12
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

106582:LOC101480640
gene id: 106582:LOC101480640
uniprot id: A0A3P9B069
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:slc45a2
gene id: 106582:slc45a2
uniprot id: A0A3P9AR49
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101470732
gene id: 106582:LOC101470732
uniprot id: A0A3P9DQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

106582:LOC101480646
gene id: 106582:LOC101480646
uniprot id: A0A3P9C4N4
names: Subcellular Location Annotation
messages: extracellular space

106582:LOC101484838
gene id: 106582:LOC101484838
uniprot id: A0A3P9BJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

106582:e2f2
gene id: 106582:e2f2
uniprot id: A0A3P9B6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

106582:LOC101466479
gene id: 106582:LOC101466479
uniprot id: A0A3P9AUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

106582:LOC101464144
gene id: 106582:LOC101464144
uniprot id: A0A3P9CZ54
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101483192
gene id: 106582:LOC101483192
uniprot id: A0A3P9CAH1
names: Similarity
messages: Belongs to the TACO1 family.

106582:LOC101473938
gene id: 106582:LOC101473938
uniprot id: A0A3P9CJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

106582:LOC101479519
gene id: 106582:LOC101479519
uniprot id: A0A3P9CZK6
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101471325
gene id: 106582:LOC101471325
uniprot id: A0A3P9CD57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

106582:LOC101480651
gene id: 106582:LOC101480651
uniprot id: A0A3P9BQ24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

106582:LOC101469783
gene id: 106582:LOC101469783
uniprot id: A0A3P9DF68
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

106582:LOC101463991
gene id: 106582:LOC101463991
uniprot id: A0A3P9DCE2
names: Similarity
messages: Belongs to the paralemmin family.

106582:LOC101466516
gene id: 106582:LOC101466516
uniprot id: A0A3P9B6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

106582:LOC101483836
gene id: 106582:LOC101483836
uniprot id: A0A3P9BR64
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

106582:ociad1
gene id: 106582:ociad1
uniprot id: A0A3P9DBP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

106582:atp1b4
gene id: 106582:atp1b4
uniprot id: A0A3P9BK70
uniprot id: A0A3P9BK82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

106582:LOC101473166
gene id: 106582:LOC101473166
uniprot id: A0A3P9BRB2
uniprot id: A0A3P9BRB6
uniprot id: A0A3P9BS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

106582:vegfb
gene id: 106582:vegfb
uniprot id: A0A3P9B9M7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

106582:LOC101485281
gene id: 106582:LOC101485281
uniprot id: A0A3P9BDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

106582:LOC101481723
gene id: 106582:LOC101481723
uniprot id: A0A3P9C396
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101470553
gene id: 106582:LOC101470553
uniprot id: A0A3P9C6U4
uniprot id: A0A3P9C7B5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

106582:LOC101471951
gene id: 106582:LOC101471951
uniprot id: A0A3P9DNH1
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

106582:bmp5
gene id: 106582:bmp5
uniprot id: A0A3P9B913
names: Similarity
messages: Belongs to the TGF-beta family.

106582:pdgfc
gene id: 106582:pdgfc
uniprot id: A0A3P9AWY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

106582:prim1
gene id: 106582:prim1
uniprot id: A0A3P9DJD8
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

106582:LOC101478392
gene id: 106582:LOC101478392
uniprot id: A0A3P9DHS3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:gpatch11
gene id: 106582:gpatch11
uniprot id: A0A3P9BTJ8
names: Similarity
messages: Belongs to the GPATCH11 family.

106582:LOC101467538
gene id: 106582:LOC101467538
uniprot id: A0A3P9AXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

106582:tmed10
gene id: 106582:tmed10
uniprot id: A0A3P9CI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:LOC101482677
gene id: 106582:LOC101482677
uniprot id: A0A3P9B3T1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106582:LOC101476901
gene id: 106582:LOC101476901
uniprot id: A0A3P9DPD4
names: Subcellular Location Annotation
messages: Nucleus

106582:sfmbt1
gene id: 106582:sfmbt1
uniprot id: A0A3P9BZN3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101486463
gene id: 106582:LOC101486463
uniprot id: A0A3P9DJ81
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

106582:megf6
gene id: 106582:megf6
uniprot id: A0A3P9C984
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101479747
gene id: 106582:LOC101479747
uniprot id: A0A3P9BF69
names: Similarity
messages: Belongs to the FAM20 family.

106582:hdhd2
gene id: 106582:hdhd2
uniprot id: A0A3P9CHY3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

106582:LOC101473164
gene id: 106582:LOC101473164
uniprot id: A0A3P9C468
uniprot id: A0A3P9C4G7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106582:LOC101481315
gene id: 106582:LOC101481315
uniprot id: A0A3P9BXR3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

106582:LOC101471655
gene id: 106582:LOC101471655
uniprot id: A0A3P9DNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

106582:ndufs4
gene id: 106582:ndufs4
uniprot id: A0A3P9C344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

106582:slc43a3
gene id: 106582:slc43a3
uniprot id: A0A3P9B1G1
names: Subcellular Location Annotation
messages: Membrane

106582:nppc
gene id: 106582:nppc
uniprot id: A0A3P9CLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

106582:cep57l1
gene id: 106582:cep57l1
uniprot id: A0A3P9CP84
names: Similarity
messages: Belongs to the translokin family.

106582:nr2f2
gene id: 106582:nr2f2
uniprot id: A0A3P9D2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

106582:LOC101480834
gene id: 106582:LOC101480834
uniprot id: A0A3P9DIW2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:prpf18
gene id: 106582:prpf18
uniprot id: A0A3P9CVA5
uniprot id: A0A3P9CVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

106582:orc3
gene id: 106582:orc3
uniprot id: A0A3P9BB01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

106582:LOC101481180
gene id: 106582:LOC101481180
uniprot id: A0A3P9B9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

106582:rps25
gene id: 106582:rps25
uniprot id: A0A3P9C4X1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

106582:LOC101481506
gene id: 106582:LOC101481506
uniprot id: A0A3P9CEU7
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

106582:arl5a
gene id: 106582:arl5a
uniprot id: A0A3P9CSH0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

106582:tcf7l1
gene id: 106582:tcf7l1
uniprot id: A0A3P9BYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

106582:dct
gene id: 106582:dct
uniprot id: A0A3P9B1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

106582:LOC101484978
gene id: 106582:LOC101484978
uniprot id: A0A3P9BZY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

106582:dram2
gene id: 106582:dram2
uniprot id: A0A3P9CKW0
names: Subcellular Location Annotation
messages: Membrane

106582:vamp4
gene id: 106582:vamp4
uniprot id: A0A3P9CW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

106582:LOC101478433
gene id: 106582:LOC101478433
uniprot id: A0A3P9BEM4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

106582:LOC101465786
gene id: 106582:LOC101465786
uniprot id: A0A3P9CR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

106582:LOC101478977
gene id: 106582:LOC101478977
uniprot id: A0A3P9D0B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

106582:tpst1
gene id: 106582:tpst1
uniprot id: A0A3P9DHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

106582:LOC101465564
gene id: 106582:LOC101465564
uniprot id: A0A3P9CXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

106582:LOC101485986
gene id: 106582:LOC101485986
uniprot id: A0A3P9B1W7
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:LOC101468055
gene id: 106582:LOC101468055
uniprot id: A0A3P9DCE8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

106582:xrn1
gene id: 106582:xrn1
uniprot id: A0A3P9CDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

106582:LOC101477368
gene id: 106582:LOC101477368
uniprot id: A0A3P9CUG6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:LOC101486636
gene id: 106582:LOC101486636
uniprot id: A0A3P9DMT6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

106582:asah2
gene id: 106582:asah2
uniprot id: A0A3P9C649
names: Similarity
messages: Belongs to the neutral ceramidase family.

106582:snu13
gene id: 106582:snu13
uniprot id: A0A3P9BPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

106582:cxcr4
gene id: 106582:cxcr4
uniprot id: A0A3P9C4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

106582:stard5
gene id: 106582:stard5
uniprot id: A0A3P9CJV2
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

106582:LOC101481144
gene id: 106582:LOC101481144
uniprot id: A0A3P9CBG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

106582:LOC101487279
gene id: 106582:LOC101487279
uniprot id: A0A3P9C0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

106582:LOC101481900
gene id: 106582:LOC101481900
uniprot id: A0A3P9B6J9
names: Similarity
messages: Belongs to the dapper family.

106582:LOC101479919
gene id: 106582:LOC101479919
uniprot id: A0A3P9C753
uniprot id: A0A3P9C7S5
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

106582:idh3b
gene id: 106582:idh3b
uniprot id: A0A3P9DPB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

106582:LOC101482496
gene id: 106582:LOC101482496
uniprot id: A0A3P9B6M8
names: Similarity
messages: Belongs to the ATG8 family.

106582:cpxm2
gene id: 106582:cpxm2
uniprot id: A0A3P9AVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

106582:LOC101473653
gene id: 106582:LOC101473653
uniprot id: A0A3P9DGR1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

106582:wipi2
gene id: 106582:wipi2
uniprot id: A0A3P9BIL2
uniprot id: A0A3P9BIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

106582:gins2
gene id: 106582:gins2
uniprot id: A0A3P9C325
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

106582:sdhd
gene id: 106582:sdhd
uniprot id: A0A3P9CUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

106582:LOC101487991
gene id: 106582:LOC101487991
uniprot id: A0A3P9DNP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

106582:LOC101485182
gene id: 106582:LOC101485182
uniprot id: A0A3P9AV01
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

106582:xrcc5
gene id: 106582:xrcc5
uniprot id: A0A3P9BJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

106582:LOC101479261
gene id: 106582:LOC101479261
uniprot id: A0A3P9CSU5
names: Similarity
messages: Belongs to the AAA ATPase family.

106582:matk
gene id: 106582:matk
uniprot id: A0A3P9B4E7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:LOC101480684
gene id: 106582:LOC101480684
uniprot id: A0A3P9DSP6
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101482841
gene id: 106582:LOC101482841
uniprot id: A0A3P9CPJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

106582:LOC101470854
gene id: 106582:LOC101470854
uniprot id: A0A3P9C4A2
names: Similarity
messages: Belongs to the copine family.

106582:LOC101478239
gene id: 106582:LOC101478239
uniprot id: A0A3P9CS22
uniprot id: A0A3P9CS55
names: Similarity
messages: Belongs to the ARTD/PARP family.

106582:LOC101470167
gene id: 106582:LOC101470167
uniprot id: A0A3P9C409
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

106582:itga2
gene id: 106582:itga2
uniprot id: A0A3P9C2H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

106582:LOC101485289
gene id: 106582:LOC101485289
uniprot id: A0A3P9DF93
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

106582:lum
gene id: 106582:lum
uniprot id: A0A3P9BB08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

106582:rabac1
gene id: 106582:rabac1
uniprot id: A0A3P9CRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

106582:LOC101482128
gene id: 106582:LOC101482128
uniprot id: A0A3P9BHL0
names: Similarity
messages: Belongs to the MARCKS family.

106582:LOC101477118
gene id: 106582:LOC101477118
uniprot id: A0A3P9CGV4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101482142
gene id: 106582:LOC101482142
uniprot id: A0A3P9ATV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

106582:LOC101465346
gene id: 106582:LOC101465346
uniprot id: A0A3P9BXT2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

106582:nxpe3
gene id: 106582:nxpe3
uniprot id: A0A3P9D516
names: Similarity
messages: Belongs to the NXPE family.

106582:tacc1
gene id: 106582:tacc1
uniprot id: A0A3P9CK04
uniprot id: A0A3P9CK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

106582:eml4
gene id: 106582:eml4
uniprot id: A0A3P9CQX3
uniprot id: A0A3P9CQY2
uniprot id: A0A3P9CR06
names: Similarity
messages: Belongs to the WD repeat EMAP family.

106582:LOC101466193
gene id: 106582:LOC101466193
uniprot id: A0A3P9CG73
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

106582:tmem41a
gene id: 106582:tmem41a
uniprot id: A0A3P9BK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

106582:psmd1
gene id: 106582:psmd1
uniprot id: A0A3P9CPH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

106582:nkiras1
gene id: 106582:nkiras1
uniprot id: A0A3P9CL11
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

106582:LOC101477749
gene id: 106582:LOC101477749
uniprot id: A0A3P9BTG9
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101479578
gene id: 106582:LOC101479578
uniprot id: A0A3P9BUU8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

106582:cyhr1
gene id: 106582:cyhr1
uniprot id: A0A3P9BC68
names: Similarity
messages: Belongs to the ZFTRAF1 family.

106582:LOC101468279
gene id: 106582:LOC101468279
uniprot id: A0A3P9DDU0
uniprot id: A0A3P9DEE1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

106582:LOC101484052
gene id: 106582:LOC101484052
uniprot id: A0A3P9CLQ9
names: Similarity
messages: Belongs to the Bcl-2 family.

106582:LOC101463622
gene id: 106582:LOC101463622
uniprot id: A0A3P9DN30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:cul5
gene id: 106582:cul5
uniprot id: A0A3P9BX20
names: Similarity
messages: Belongs to the cullin family.

106582:LOC101480618
gene id: 106582:LOC101480618
uniprot id: A0A3P9DJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

106582:LOC101466924
gene id: 106582:LOC101466924
uniprot id: A0A3P9AYI0
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101482831
gene id: 106582:LOC101482831
uniprot id: A0A3P9C214
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:olfml2a
gene id: 106582:olfml2a
uniprot id: A0A3P9CNW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101484206
gene id: 106582:LOC101484206
uniprot id: A0A3P9B407
names: Subcellular Location Annotation
messages: Cytoplasm

106582:LOC101465064
gene id: 106582:LOC101465064
uniprot id: A0A3P9BX41
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:upp2
gene id: 106582:upp2
uniprot id: A0A3P9BP52
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

106582:LOC101480119
gene id: 106582:LOC101480119
uniprot id: A0A3P9BB89
uniprot id: A0A3P9BBK4
names: Similarity
messages: Belongs to the dynein intermediate chain family.

106582:yju2
gene id: 106582:yju2
uniprot id: A0A3P9ARC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

106582:l3hypdh
gene id: 106582:l3hypdh
uniprot id: A0A3P9CIJ9
names: Similarity
messages: Belongs to the proline racemase family.

106582:gdap1l1
gene id: 106582:gdap1l1
uniprot id: A0A3P9DAY9
names: Similarity
messages: Belongs to the GST superfamily.

106582:LOC101475237
gene id: 106582:LOC101475237
uniprot id: A0A3P9AVP6
uniprot id: A0A3P9AVW6
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

106582:nbl1
gene id: 106582:nbl1
uniprot id: A0A3P9BZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

106582:tm4sf5
gene id: 106582:tm4sf5
uniprot id: A0A3P9D2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

106582:LOC101464518
gene id: 106582:LOC101464518
uniprot id: A0A3P9D9F1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101469390
gene id: 106582:LOC101469390
uniprot id: A0A3P9B7Q3
uniprot id: A0A3P9B7S0
uniprot id: A0A3P9B7X9
uniprot id: A0A3P9B820
names: Subcellular Location Annotation
messages: Z line

106582:scamp3
gene id: 106582:scamp3
uniprot id: A0A3P9DMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

106582:LOC101480272
gene id: 106582:LOC101480272
uniprot id: A0A3P9DR18
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

106582:LOC101469223
gene id: 106582:LOC101469223
uniprot id: A0A3P9C4H7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

106582:LOC101478254
gene id: 106582:LOC101478254
uniprot id: A0A3P9BZR8
names: Subcellular Location Annotation
messages: Nucleus

106582:ift122
gene id: 106582:ift122
uniprot id: A0A3P9DIH9
names: Subcellular Location Annotation
messages: cilium

106582:dym
gene id: 106582:dym
uniprot id: A0A3P9CVW8
names: Similarity
messages: Belongs to the dymeclin family.

106582:tfap2c
gene id: 106582:tfap2c
uniprot id: A0A3P9B9Q5
uniprot id: A0A3P9B9Q9
uniprot id: A0A3P9B9U9
names: Similarity
messages: Belongs to the AP-2 family.

106582:npb
gene id: 106582:npb
uniprot id: A0A3P9BKN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

106582:dync1li2
gene id: 106582:dync1li2
uniprot id: A0A3P9AZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

106582:ccm2l
gene id: 106582:ccm2l
uniprot id: A0A3P9DNF9
names: Similarity
messages: Belongs to the CCM2 family.

106582:LOC101477647
gene id: 106582:LOC101477647
uniprot id: A0A3P9DQ78
names: Subcellular Location Annotation
messages: Cytoplasm

106582:mea1
gene id: 106582:mea1
uniprot id: A0A3P9AZ84
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

106582:hadhb
gene id: 106582:hadhb
uniprot id: A0A3P9B8B5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106582:dpp3
gene id: 106582:dpp3
uniprot id: A0A3P9AUT6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

106582:LOC101467608
gene id: 106582:LOC101467608
uniprot id: A0A3P9C9Q4
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101483175
gene id: 106582:LOC101483175
uniprot id: A0A3P9CGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

106582:slain2
gene id: 106582:slain2
uniprot id: A0A3P9CYQ5
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

106582:LOC101470327
gene id: 106582:LOC101470327
uniprot id: A0A3P9C646
uniprot id: A0A3P9C665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

106582:LOC101479249
gene id: 106582:LOC101479249
uniprot id: A0A3P9DR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

106582:LOC101472607
gene id: 106582:LOC101472607
uniprot id: A0A3P9C431
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

106582:rara
gene id: 106582:rara
uniprot id: A0A3P9BT32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

106582:grm1
gene id: 106582:grm1
uniprot id: A0A3P9CN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

106582:LOC106676295
gene id: 106582:LOC106676295
uniprot id: A0A3P9BBP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

106582:spdef
gene id: 106582:spdef
uniprot id: A0A3P9AZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:coq7
gene id: 106582:coq7
uniprot id: A0A3P9BRZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

106582:LOC101485426
gene id: 106582:LOC101485426
uniprot id: A0A3P9B320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

106582:nobox
gene id: 106582:nobox
uniprot id: A0A3P9BCV6
names: Subcellular Location Annotation
messages: Nucleus

106582:ppp2r5e
gene id: 106582:ppp2r5e
uniprot id: A0A3P9AVL8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

106582:LOC101464664
gene id: 106582:LOC101464664
uniprot id: A0A3P9C4P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:LOC101467170
gene id: 106582:LOC101467170
uniprot id: A0A3P9BMB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:nt5dc1
gene id: 106582:nt5dc1
uniprot id: A0A3P9CFX3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

106582:LOC101472641
gene id: 106582:LOC101472641
uniprot id: A0A3P9DRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

106582:sec62
gene id: 106582:sec62
uniprot id: A0A3P9DEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

106582:nsun5
gene id: 106582:nsun5
uniprot id: A0A3P9D062
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

106582:LOC101487843
gene id: 106582:LOC101487843
uniprot id: A0A3P9D7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

106582:LOC101470571
gene id: 106582:LOC101470571
uniprot id: A0A3P9AUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

106582:prdm13
gene id: 106582:prdm13
uniprot id: A0A3P9C0I9
names: Subcellular Location Annotation
messages: Nucleus

106582:syk
gene id: 106582:syk
uniprot id: A0A3P9BX90
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

106582:LOC101472631
gene id: 106582:LOC101472631
uniprot id: A0A3P9B1E3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

106582:spg7
gene id: 106582:spg7
uniprot id: A0A3P9AYA3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

106582:gcat
gene id: 106582:gcat
uniprot id: A0A3P9B6A4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

106582:tmod3
gene id: 106582:tmod3
uniprot id: A0A3P9BI71
names: Subcellular Location Annotation
messages: cytoskeleton

106582:LOC101475762
gene id: 106582:LOC101475762
uniprot id: A0A3P9BKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

106582:npc1
gene id: 106582:npc1
uniprot id: A0A3P9DFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

106582:LOC101469304
gene id: 106582:LOC101469304
uniprot id: A0A3P9B245
uniprot id: A0A3P9B251
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

106582:LOC101466677
gene id: 106582:LOC101466677
uniprot id: A0A3P9BCZ8
names: Subcellular Location Annotation
messages: Nucleus

106582:appl1
gene id: 106582:appl1
uniprot id: A0A3P9CHA0
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

106582:furin
gene id: 106582:furin
uniprot id: A0A3P9CN13
names: Similarity
messages: Belongs to the peptidase S8 family.

106582:LOC101481325
gene id: 106582:LOC101481325
uniprot id: A0A3P9DN79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

106582:naa10
gene id: 106582:naa10
uniprot id: A0A3P9DPW9
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

106582:LOC101470161
gene id: 106582:LOC101470161
uniprot id: A0A3P9DMC0
names: Similarity
messages: Belongs to the actin family.

106582:ttc21b
gene id: 106582:ttc21b
uniprot id: A0A3P9BFM4
names: Similarity
messages: Belongs to the TTC21 family.

106582:LOC101479609
gene id: 106582:LOC101479609
uniprot id: A0A3P9CRR4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

106582:LOC101477097
gene id: 106582:LOC101477097
uniprot id: A0A3P9D8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

106582:pet117
gene id: 106582:pet117
uniprot id: A0A3P9CDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

106582:zc3hc1
gene id: 106582:zc3hc1
uniprot id: A0A3P9BHN3
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101483030
gene id: 106582:LOC101483030
uniprot id: A0A3P9BK98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101476411
gene id: 106582:LOC101476411
uniprot id: A0A3P9B5P4
uniprot id: A0A3P9B5R2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:LOC101476634
gene id: 106582:LOC101476634
uniprot id: A0A3P9B3E3
names: Similarity
messages: Belongs to the TGF-beta family.

106582:ctnnb1
gene id: 106582:ctnnb1
uniprot id: A0A3P9AZ06
uniprot id: A0A3P9AZ50
names: Similarity
messages: Belongs to the beta-catenin family.

106582:mrps18a
gene id: 106582:mrps18a
uniprot id: A0A3P9CC68
names: Subcellular Location Annotation
messages: Mitochondrion

106582:cluh
gene id: 106582:cluh
uniprot id: A0A3P9CDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

106582:LOC101470679
gene id: 106582:LOC101470679
uniprot id: A0A3P9CPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: centrosome

106582:timm23
gene id: 106582:timm23
uniprot id: A0A3P9B8A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

106582:LOC101464626
gene id: 106582:LOC101464626
uniprot id: A0A3P9C4V8
names: Subcellular Location Annotation
messages: Membrane

106582:LOC101480225
gene id: 106582:LOC101480225
uniprot id: A0A3P9CT07
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101482617
gene id: 106582:LOC101482617
uniprot id: A0A3P9DD62
names: Similarity
messages: Belongs to the TMEM14 family.

106582:LOC101478170
gene id: 106582:LOC101478170
uniprot id: A0A3P9BN37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

106582:LOC101476055
gene id: 106582:LOC101476055
uniprot id: A0A3P9BZT9
names: Similarity
messages: Belongs to the BTG family.

106582:LOC101485153
gene id: 106582:LOC101485153
uniprot id: A0A3P9D3A2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106582:LOC101482592
gene id: 106582:LOC101482592
uniprot id: A0A3P9B8K1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

106582:LOC101469331
gene id: 106582:LOC101469331
uniprot id: A0A3P9CES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

106582:galnt3
gene id: 106582:galnt3
uniprot id: A0A3P9BFB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

106582:sec24d
gene id: 106582:sec24d
uniprot id: A0A3P9AX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

106582:dtx2
gene id: 106582:dtx2
uniprot id: A0A3P9BZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

106582:rtca
gene id: 106582:rtca
uniprot id: A0A3P9CPM6
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

106582:bbox1
gene id: 106582:bbox1
uniprot id: A0A3P9C8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

106582:APK84 gp02
gene id: 106582:APK84_gp02
uniprot id: A0A0K2CJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

106582:LOC101470392
gene id: 106582:LOC101470392
uniprot id: A0A3P9D019
names: Similarity
messages: Belongs to the FHIP family.

106582:fyn
gene id: 106582:fyn
uniprot id: A0A3P9CGG5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

106582:LOC101480486
gene id: 106582:LOC101480486
uniprot id: A0A3P9CWU4
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101482277
gene id: 106582:LOC101482277
uniprot id: A0A3P9AYA6
names: Similarity
messages: Belongs to the BtpA family.

106582:LOC101465869
gene id: 106582:LOC101465869
uniprot id: A0A3P9BIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

106582:fam98b
gene id: 106582:fam98b
uniprot id: A0A3P9B0K2
names: Similarity
messages: Belongs to the FAM98 family.

106582:LOC101470525
gene id: 106582:LOC101470525
uniprot id: A0A3P9BKH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

106582:LOC101486776
gene id: 106582:LOC101486776
uniprot id: A0A3P9CV44
uniprot id: A0A3P9CVW1
names: Similarity
messages: Belongs to the TTC39 family.

106582:stk38l
gene id: 106582:stk38l
uniprot id: A0A3P9CCV4
names: Similarity
messages: Belongs to the protein kinase superfamily.

106582:gfm1
gene id: 106582:gfm1
uniprot id: A0A3P9CJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

106582:mtf2
gene id: 106582:mtf2
uniprot id: A0A3P9B7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

106582:LOC101479280
gene id: 106582:LOC101479280
uniprot id: A0A3P9D2D4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:LOC101476048
gene id: 106582:LOC101476048
uniprot id: A0A3P9B3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

106582:LOC101487355
gene id: 106582:LOC101487355
uniprot id: A0A3P9BX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

106582:irf2bp2
gene id: 106582:irf2bp2
uniprot id: A0A3P9BT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

106582:LOC101467005
gene id: 106582:LOC101467005
uniprot id: A0A3P9BJF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:LOC101477131
gene id: 106582:LOC101477131
uniprot id: A0A3P9C3P6
names: Similarity
messages: Belongs to the stathmin family.

106582:mastl
gene id: 106582:mastl
uniprot id: A0A3P9CS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

106582:imp4
gene id: 106582:imp4
uniprot id: A0A3P9B5P6
names: Subcellular Location Annotation
messages: nucleolus

106582:LOC101470365
gene id: 106582:LOC101470365
uniprot id: A0A3P9DH90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

106582:LOC101485449
gene id: 106582:LOC101485449
uniprot id: A0A3P9DPT8
names: Similarity
messages: Belongs to the WAPL family.

106582:LOC101470568
gene id: 106582:LOC101470568
uniprot id: A0A3P9C3M0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

106582:tmem151b
gene id: 106582:tmem151b
uniprot id: A0A3P9AVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

106582:gpx8
gene id: 106582:gpx8
uniprot id: A0A3P9C3X5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

106582:thrb
gene id: 106582:thrb
uniprot id: A0A3P9CKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

106582:LOC101483998
gene id: 106582:LOC101483998
uniprot id: A0A3P9BJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

106582:LOC101474933
gene id: 106582:LOC101474933
uniprot id: A0A3P9DK76
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:oat
gene id: 106582:oat
uniprot id: A0A3P9AW59
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

106582:ints11
gene id: 106582:ints11
uniprot id: A0A3P9DAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

106582:LOC101470780
gene id: 106582:LOC101470780
uniprot id: A0A3P9BAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

106582:LOC101475233
gene id: 106582:LOC101475233
uniprot id: A0A3P9BG39
names: Similarity
messages: Belongs to the copine family.

106582:hlx
gene id: 106582:hlx
uniprot id: A0A3P9AUW3
uniprot id: A0A3P9AV42
names: Subcellular Location Annotation
messages: Nucleus

106582:wdyhv1
gene id: 106582:wdyhv1
uniprot id: A0A3P9C1J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

106582:psmc6
gene id: 106582:psmc6
uniprot id: A0A3P9CBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

106582:strn
gene id: 106582:strn
uniprot id: A0A3P9BS53
uniprot id: A0A3P9BT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

106582:tomm22
gene id: 106582:tomm22
uniprot id: A0A3P9BH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

106582:lancl2
gene id: 106582:lancl2
uniprot id: A0A3P9CFI8
names: Similarity
messages: Belongs to the LanC-like protein family.

106582:LOC101464969
gene id: 106582:LOC101464969
uniprot id: A0A3P9AYZ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

106582:LOC101476322
gene id: 106582:LOC101476322
uniprot id: A0A3P9CRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

106582:LOC101471015
gene id: 106582:LOC101471015
uniprot id: A0A3P9BYK0
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101477122
gene id: 106582:LOC101477122
uniprot id: A0A3P9CIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

106582:LOC101464087
gene id: 106582:LOC101464087
uniprot id: A0A3P9DH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

106582:ppcs
gene id: 106582:ppcs
uniprot id: A0A3P9CAY0
names: Similarity
messages: Belongs to the PPC synthetase family.

106582:acat2
gene id: 106582:acat2
uniprot id: A0A3P9CQA4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106582:psmd13
gene id: 106582:psmd13
uniprot id: A0A3P9CIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

106582:LOC101469904
gene id: 106582:LOC101469904
uniprot id: A0A3P9BAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

106582:rpl18a
gene id: 106582:rpl18a
uniprot id: A0A3P9CSS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

106582:LOC101481859
gene id: 106582:LOC101481859
uniprot id: A0A3P9BXB6
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

106582:LOC101474397
gene id: 106582:LOC101474397
uniprot id: A0A3P9CMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

106582:LOC101474983
gene id: 106582:LOC101474983
uniprot id: A0A3P9CVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

106582:ube2e1
gene id: 106582:ube2e1
uniprot id: A0A3P9CL01
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

106582:lin52
gene id: 106582:lin52
uniprot id: A0A3P9BQD1
names: Similarity
messages: Belongs to the lin-52 family.

106582:LOC101478534
gene id: 106582:LOC101478534
uniprot id: A0A3P9ARC5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

106582:olfm2
gene id: 106582:olfm2
uniprot id: A0A3P9CRV7
uniprot id: A0A3P9CSS4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

106582:LOC101478984
gene id: 106582:LOC101478984
uniprot id: A0A3P9CRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

106582:dpcd
gene id: 106582:dpcd
uniprot id: A0A3P9BNN5
names: Similarity
messages: Belongs to the DPCD family.

106582:gdf6
gene id: 106582:gdf6
uniprot id: A0A3P9DJM2
names: Similarity
messages: Belongs to the TGF-beta family.

106582:LOC101487503
gene id: 106582:LOC101487503
uniprot id: A0A3P9CH80
uniprot id: A0A3P9CHI8
names: Similarity
messages: Belongs to the pyruvate kinase family.

106582:LOC101465923
gene id: 106582:LOC101465923
uniprot id: A0A3P9CEW5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

106582:LOC101469631
gene id: 106582:LOC101469631
uniprot id: A0A3P9C3F0
names: Subcellular Location Annotation
messages: cytoskeleton

106582:tarbp2
gene id: 106582:tarbp2
uniprot id: A0A3P9BGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

106582:ewsr1
gene id: 106582:ewsr1
uniprot id: A0A3P9CN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

106582:LOC101467975
gene id: 106582:LOC101467975
uniprot id: A0A3P9D265
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

106582:wars
gene id: 106582:wars
uniprot id: A0A3P9B8A6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106582:LOC101470750
gene id: 106582:LOC101470750
uniprot id: A0A3P9BD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

106582:lhx6
gene id: 106582:lhx6
uniprot id: A0A3P9CPD8
names: Subcellular Location Annotation
messages: Nucleus

106582:LOC101472902
gene id: 106582:LOC101472902
uniprot id: A0A3P9DL27
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

106582:LOC101463907
gene id: 106582:LOC101463907
uniprot id: A0A3P9BV04
names: Similarity
messages: Belongs to the OSBP family.

106582:LOC101487783
gene id: 106582:LOC101487783
uniprot id: A0A3P9CAR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106582:tmem35a
gene id: 106582:tmem35a
uniprot id: A0A3P9BH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

106582:ppm1d
gene id: 106582:ppm1d
uniprot id: A0A3P9AWP4
names: Similarity
messages: Belongs to the PP2C family.

106582:LOC101467805
gene id: 106582:LOC101467805
uniprot id: A0A3P9C6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

106582:LOC101472778
gene id: 106582:LOC101472778
uniprot id: A0A3P9CPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

106582:kiaa1147
gene id: 106582:kiaa1147
uniprot id: A0A3P9CJQ6
names: Similarity
messages: Belongs to the DENND11 family.

106582:sec22c
gene id: 106582:sec22c
uniprot id: A0A3P9CWR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

106582:LOC101477649
gene id: 106582:LOC101477649
uniprot id: A0A3P9CWZ5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

106582:tmem159
gene id: 106582:tmem159
uniprot id: A0A3P9B5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

106582:tmcc1
gene id: 106582:tmcc1
uniprot id: A0A3P9ARB9
uniprot id: A0A3P9ARC2
uniprot id: A0A3P9ARD3
names: Similarity
messages: Belongs to the TEX28 family.

106582:gabrg3
gene id: 106582:gabrg3
uniprot id: A0A3P9BKE8
uniprot id: A0A3P9BKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

106582:tcp11l1
gene id: 106582:tcp11l1
uniprot id: A0A3P9C3L2
names: Similarity
messages: Belongs to the TCP11 family.

106582:map3k8
gene id: 106582:map3k8
uniprot id: A0A3P9CIS7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

106582:LOC101475311
gene id: 106582:LOC101475311
uniprot id: A0A3P9CC29
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106582:sept8
gene id: 106582:sept8
uniprot id: A0A3P9B2X7
uniprot id: A0A3P9B2Z3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

106582:rps13
gene id: 106582:rps13
uniprot id: A0A3P9C2H0
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

106582:ptpa
gene id: 106582:ptpa
uniprot id: A0A3P9AU93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.