1064539:Sp245p RS05355
gene id: 1064539:Sp245p_RS05355
uniprot id: G8AEV3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1064539:Sp245p RS10325
gene id: 1064539:Sp245p_RS10325
uniprot id: G8AKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1064539:Sp245p RS03230
gene id: 1064539:Sp245p_RS03230
uniprot id: G8AHR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1064539:Sp245p RS26220
gene id: 1064539:Sp245p_RS26220
uniprot id: G8B1G8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1064539:Sp245p RS10515
gene id: 1064539:Sp245p_RS10515
uniprot id: G8AKJ7
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1064539:Sp245p RS25425
gene id: 1064539:Sp245p_RS25425
uniprot id: G8AYM9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1064539:Sp245p RS21305
gene id: 1064539:Sp245p_RS21305
uniprot id: G8ATS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS07580
gene id: 1064539:Sp245p_RS07580
uniprot id: G8AMI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1064539:Sp245p RS32845
gene id: 1064539:Sp245p_RS32845
uniprot id: G8AYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1064539:Sp245p RS05010
gene id: 1064539:Sp245p_RS05010
uniprot id: G8AFJ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1064539:Sp245p RS28990
gene id: 1064539:Sp245p_RS28990
uniprot id: G8AW00
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS16930
gene id: 1064539:Sp245p_RS16930
uniprot id: G8AQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS13050
gene id: 1064539:Sp245p_RS13050
uniprot id: G8AIV7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS14620
gene id: 1064539:Sp245p_RS14620
uniprot id: G8APD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1064539:Sp245p RS04590
gene id: 1064539:Sp245p_RS04590
uniprot id: G8AFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS22990
gene id: 1064539:Sp245p_RS22990
uniprot id: G8AXW9
names: Similarity
messages: Belongs to the PrpF family.

1064539:Sp245p RS05715
gene id: 1064539:Sp245p_RS05715
uniprot id: G8AEM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1064539:Sp245p RS20585
gene id: 1064539:Sp245p_RS20585
uniprot id: G8ATB0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1064539:Sp245p RS31230
gene id: 1064539:Sp245p_RS31230
uniprot id: G8B0U5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS22795
gene id: 1064539:Sp245p_RS22795
uniprot id: G8AY07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1064539:Sp245p RS09785
gene id: 1064539:Sp245p_RS09785
uniprot id: G8AL03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1064539:Sp245p RS01655
gene id: 1064539:Sp245p_RS01655
uniprot id: G8AFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Membrane

1064539:Sp245p RS26850
gene id: 1064539:Sp245p_RS26850
uniprot id: G8AUI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS22995
gene id: 1064539:Sp245p_RS22995
uniprot id: G8AXW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS11880
gene id: 1064539:Sp245p_RS11880
uniprot id: G8AJM6
names: Similarity
messages: Belongs to the PhoH family.

1064539:Sp245p RS24815
gene id: 1064539:Sp245p_RS24815
uniprot id: G8AWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS07885
gene id: 1064539:Sp245p_RS07885
uniprot id: G8AMQ2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1064539:Sp245p RS14150
gene id: 1064539:Sp245p_RS14150
uniprot id: G8AI13
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1064539:Sp245p RS15105
gene id: 1064539:Sp245p_RS15105
uniprot id: G8APN6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1064539:Sp245p RS22195
gene id: 1064539:Sp245p_RS22195
uniprot id: G8AP61
names: Function
names: Subunit
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring.
messages: Homodimer.

1064539:Sp245p RS11805
gene id: 1064539:Sp245p_RS11805
uniprot id: G8AJP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

1064539:Sp245p RS20240
gene id: 1064539:Sp245p_RS20240
uniprot id: G8AT33
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1064539:Sp245p RS21800
gene id: 1064539:Sp245p_RS21800
uniprot id: G8ANX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1064539:Sp245p RS01930
gene id: 1064539:Sp245p_RS01930
uniprot id: G8AF75
names: Similarity
messages: Belongs to the HSP15 family.

1064539:Sp245p RS11350
gene id: 1064539:Sp245p_RS11350
uniprot id: G8AJZ5
names: Similarity
messages: Belongs to the YciI family.

1064539:Sp245p RS13835
gene id: 1064539:Sp245p_RS13835
uniprot id: G8AI85
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS28845
gene id: 1064539:Sp245p_RS28845
uniprot id: G8AVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS17665
gene id: 1064539:Sp245p_RS17665
uniprot id: G8ARD0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1064539:Sp245p RS14345
gene id: 1064539:Sp245p_RS14345
uniprot id: G8AHW7
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1064539:Sp245p RS27320
gene id: 1064539:Sp245p_RS27320
uniprot id: G8AUT9
names: Function
messages: Acts on leucine, isoleucine and valine.

1064539:Sp245p RS09280
gene id: 1064539:Sp245p_RS09280
uniprot id: G8B0A9
names: Similarity
messages: Belongs to the TPP enzyme family.

1064539:Sp245p RS03105
gene id: 1064539:Sp245p_RS03105
uniprot id: G8AHU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS25485
gene id: 1064539:Sp245p_RS25485
uniprot id: G8AYM2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS29630
gene id: 1064539:Sp245p_RS29630
uniprot id: G8ATT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS10865
gene id: 1064539:Sp245p_RS10865
uniprot id: G8AKB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS04855
gene id: 1064539:Sp245p_RS04855
uniprot id: G8AFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1064539:Sp245p RS26635
gene id: 1064539:Sp245p_RS26635
uniprot id: G8B183
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1064539:Sp245p RS12565
gene id: 1064539:Sp245p_RS12565
uniprot id: G8AJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS00815
gene id: 1064539:Sp245p_RS00815
uniprot id: G8AGD5
names: Similarity
messages: Belongs to the peptidase C15 family.

1064539:Sp245p RS08785
gene id: 1064539:Sp245p_RS08785
uniprot id: G8ALM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1064539:Sp245p RS30470
gene id: 1064539:Sp245p_RS30470
uniprot id: G8AUD7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1064539:Sp245p RS07555
gene id: 1064539:Sp245p_RS07555
uniprot id: G8AMH5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1064539:Sp245p RS17570
gene id: 1064539:Sp245p_RS17570
uniprot id: G8ARA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1064539:Sp245p RS25450
gene id: 1064539:Sp245p_RS25450
uniprot id: G8AYM6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1064539:Sp245p RS21665
gene id: 1064539:Sp245p_RS21665
uniprot id: G8ANU3
names: Similarity
messages: Belongs to the HupF/HypC family.

1064539:Sp245p RS08340
gene id: 1064539:Sp245p_RS08340
uniprot id: G8ALX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1064539:Sp245p RS18640
gene id: 1064539:Sp245p_RS18640
uniprot id: G8AS03
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1064539:Sp245p RS01860
gene id: 1064539:Sp245p_RS01860
uniprot id: G8AF91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06490
gene id: 1064539:Sp245p_RS06490
uniprot id: G8AN57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS09575
gene id: 1064539:Sp245p_RS09575
uniprot id: G8AL50
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS10660
gene id: 1064539:Sp245p_RS10660
uniprot id: G8AKG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1064539:Sp245p RS08010
gene id: 1064539:Sp245p_RS08010
uniprot id: G8AMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS16000
gene id: 1064539:Sp245p_RS16000
uniprot id: G8AQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS16770
gene id: 1064539:Sp245p_RS16770
uniprot id: G8AQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1064539:Sp245p RS19365
gene id: 1064539:Sp245p_RS19365
uniprot id: G8ASI9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1064539:Sp245p RS31820
gene id: 1064539:Sp245p_RS31820
uniprot id: G8B093
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS26715
gene id: 1064539:Sp245p_RS26715
uniprot id: G8B1I9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1064539:Sp245p RS15680
gene id: 1064539:Sp245p_RS15680
uniprot id: G8AQ13
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1064539:Sp245p RS15730
gene id: 1064539:Sp245p_RS15730
uniprot id: G8AQ23
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1064539:Sp245p RS02170
gene id: 1064539:Sp245p_RS02170
uniprot id: G8AF19
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1064539:Sp245p RS23930
gene id: 1064539:Sp245p_RS23930
uniprot id: G8AX98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS01075
gene id: 1064539:Sp245p_RS01075
uniprot id: G8AG79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1064539:Sp245p RS08445
gene id: 1064539:Sp245p_RS08445
uniprot id: G8ALV1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1064539:Sp245p RS06420
gene id: 1064539:Sp245p_RS06420
uniprot id: G8AN71
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS01120
gene id: 1064539:Sp245p_RS01120
uniprot id: G8AG70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS32705
gene id: 1064539:Sp245p_RS32705
uniprot id: G8B0I2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09435
gene id: 1064539:Sp245p_RS09435
uniprot id: G8AL81
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1064539:Sp245p RS22855
gene id: 1064539:Sp245p_RS22855
uniprot id: G8AXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1064539:Sp245p RS24455
gene id: 1064539:Sp245p_RS24455
uniprot id: G8AWX6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS15340
gene id: 1064539:Sp245p_RS15340
uniprot id: G8APT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS16250
gene id: 1064539:Sp245p_RS16250
uniprot id: G8AQF1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1064539:Sp245p RS26990
gene id: 1064539:Sp245p_RS26990
uniprot id: G8AUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS28730
gene id: 1064539:Sp245p_RS28730
uniprot id: G8AVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1064539:Sp245p RS12865
gene id: 1064539:Sp245p_RS12865
uniprot id: G8AIZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS32580
gene id: 1064539:Sp245p_RS32580
uniprot id: G8B0K6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS12280
gene id: 1064539:Sp245p_RS12280
uniprot id: G8AJD1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS10015
gene id: 1064539:Sp245p_RS10015
uniprot id: G8AKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS08775
gene id: 1064539:Sp245p_RS08775
uniprot id: G8ALM3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1064539:Sp245p RS24145
gene id: 1064539:Sp245p_RS24145
uniprot id: G8AX48
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS00670
gene id: 1064539:Sp245p_RS00670
uniprot id: G8AGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1064539:Sp245p RS11645
gene id: 1064539:Sp245p_RS11645
uniprot id: G8AJS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1064539:Sp245p RS03165
gene id: 1064539:Sp245p_RS03165
uniprot id: G8AHT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1064539:Sp245p RS25360
gene id: 1064539:Sp245p_RS25360
uniprot id: G8AYP2
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS08825
gene id: 1064539:Sp245p_RS08825
uniprot id: G8ALL3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1064539:Sp245p RS09950
gene id: 1064539:Sp245p_RS09950
uniprot id: G8AKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS23305
gene id: 1064539:Sp245p_RS23305
uniprot id: G8AXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS27490
gene id: 1064539:Sp245p_RS27490
uniprot id: G8AUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1064539:Sp245p RS19710
gene id: 1064539:Sp245p_RS19710
uniprot id: G8ASR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1064539:Sp245p RS09520
gene id: 1064539:Sp245p_RS09520
uniprot id: G8AL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS25035
gene id: 1064539:Sp245p_RS25035
uniprot id: G8AWJ6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS29685
gene id: 1064539:Sp245p_RS29685
uniprot id: G8ATV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS21635
gene id: 1064539:Sp245p_RS21635
uniprot id: G8ANT8
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1064539:Sp245p RS30565
gene id: 1064539:Sp245p_RS30565
uniprot id: G8AUF8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS01130
gene id: 1064539:Sp245p_RS01130
uniprot id: G8AG68
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1064539:Sp245p RS16245
gene id: 1064539:Sp245p_RS16245
uniprot id: G8AQF0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1064539:Sp245p RS04235
gene id: 1064539:Sp245p_RS04235
uniprot id: G8AGK9
names: PTM
messages: Binds 1 heme group per subunit.

1064539:Sp245p RS06615
gene id: 1064539:Sp245p_RS06615
uniprot id: G8AN30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1064539:Sp245p RS34665
gene id: 1064539:Sp245p_RS34665
uniprot id: G8AZZ0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1064539:Sp245p RS03700
gene id: 1064539:Sp245p_RS03700
uniprot id: G8AHF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1064539:Sp245p RS06880
gene id: 1064539:Sp245p_RS06880
uniprot id: G8AM19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1064539:Sp245p RS20715
gene id: 1064539:Sp245p_RS20715
uniprot id: G8ATE0
names: Subcellular Location Annotation
messages: Mitochondrion matrix

1064539:Sp245p RS15875
gene id: 1064539:Sp245p_RS15875
uniprot id: G8AQ57
names: Similarity
messages: Belongs to the UPF0145 family.

1064539:Sp245p RS22110
gene id: 1064539:Sp245p_RS22110
uniprot id: G8AP36
names: Similarity
messages: Belongs to the TlyA family.

1064539:Sp245p RS18700
gene id: 1064539:Sp245p_RS18700
uniprot id: G8AS16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS10905
gene id: 1064539:Sp245p_RS10905
uniprot id: G8AKA6
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS34335
gene id: 1064539:Sp245p_RS34335
uniprot id: G8AZS1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1064539:Sp245p RS02750
gene id: 1064539:Sp245p_RS02750
uniprot id: G8AE81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS00810
gene id: 1064539:Sp245p_RS00810
uniprot id: G8AGD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS16135
gene id: 1064539:Sp245p_RS16135
uniprot id: G8AQC0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1064539:Sp245p RS12885
gene id: 1064539:Sp245p_RS12885
uniprot id: G8AIZ4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1064539:Sp245p RS11605
gene id: 1064539:Sp245p_RS11605
uniprot id: G8AJT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1064539:Sp245p RS01070
gene id: 1064539:Sp245p_RS01070
uniprot id: G8AG80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1064539:Sp245p RS09790
gene id: 1064539:Sp245p_RS09790
uniprot id: G8AL02
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1064539:Sp245p RS08875
gene id: 1064539:Sp245p_RS08875
uniprot id: G8ALK3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS16340
gene id: 1064539:Sp245p_RS16340
uniprot id: G8AQH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1064539:Sp245p RS03275
gene id: 1064539:Sp245p_RS03275
uniprot id: G8AHQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1064539:Sp245p RS19615
gene id: 1064539:Sp245p_RS19615
uniprot id: G8ASP3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1064539:Sp245p RS05370
gene id: 1064539:Sp245p_RS05370
uniprot id: G8AEV0
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1064539:Sp245p RS24105
gene id: 1064539:Sp245p_RS24105
uniprot id: G8AX56
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS09855
gene id: 1064539:Sp245p_RS09855
uniprot id: G8AKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1064539:Sp245p RS21315
gene id: 1064539:Sp245p_RS21315
uniprot id: G8ATS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1064539:Sp245p RS10710
gene id: 1064539:Sp245p_RS10710
uniprot id: G8AKF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1064539:Sp245p RS22295
gene id: 1064539:Sp245p_RS22295
uniprot id: G8AP91
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS15290
gene id: 1064539:Sp245p_RS15290
uniprot id: G8APS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS01755
gene id: 1064539:Sp245p_RS01755
uniprot id: G8AFB3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1064539:Sp245p RS33750
gene id: 1064539:Sp245p_RS33750
uniprot id: G8AZD5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1064539:Sp245p RS20260
gene id: 1064539:Sp245p_RS20260
uniprot id: G8AT38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1064539:Sp245p RS09100
gene id: 1064539:Sp245p_RS09100
uniprot id: G8ALE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1064539:Sp245p RS28885
gene id: 1064539:Sp245p_RS28885
uniprot id: G8AVX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1064539:Sp245p RS24770
gene id: 1064539:Sp245p_RS24770
uniprot id: G8AWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS05845
gene id: 1064539:Sp245p_RS05845
uniprot id: G8ANK4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS23135
gene id: 1064539:Sp245p_RS23135
uniprot id: G8AXT5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS29680
gene id: 1064539:Sp245p_RS29680
uniprot id: G8ATV1
names: Similarity
messages: Belongs to the HIBADH-related family.

1064539:Sp245p RS18800
gene id: 1064539:Sp245p_RS18800
uniprot id: G8AS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS10655
gene id: 1064539:Sp245p_RS10655
uniprot id: G8AKG4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS29635
gene id: 1064539:Sp245p_RS29635
uniprot id: G8ATU0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1064539:Sp245p RS22190
gene id: 1064539:Sp245p_RS22190
uniprot id: G8AP60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS30315
gene id: 1064539:Sp245p_RS30315
uniprot id: G8AUA9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS02225
gene id: 1064539:Sp245p_RS02225
uniprot id: G8AEJ6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS07520
gene id: 1064539:Sp245p_RS07520
uniprot id: G8AMG8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1064539:Sp245p RS20720
gene id: 1064539:Sp245p_RS20720
uniprot id: G8ATE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1064539:Sp245p RS12360
gene id: 1064539:Sp245p_RS12360
uniprot id: G8AJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1064539:Sp245p RS06645
gene id: 1064539:Sp245p_RS06645
uniprot id: G8AN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1064539:Sp245p RS23995
gene id: 1064539:Sp245p_RS23995
uniprot id: G8AX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS28920
gene id: 1064539:Sp245p_RS28920
uniprot id: G8AVY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS06745
gene id: 1064539:Sp245p_RS06745
uniprot id: G8AN01
names: Similarity
messages: Belongs to the GcvT family.

1064539:Sp245p RS03175
gene id: 1064539:Sp245p_RS03175
uniprot id: G8AHT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1064539:Sp245p RS06190
gene id: 1064539:Sp245p_RS06190
uniprot id: G8ANC6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1064539:Sp245p RS25390
gene id: 1064539:Sp245p_RS25390
uniprot id: G8AYN6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1064539:Sp245p RS13970
gene id: 1064539:Sp245p_RS13970
uniprot id: G8AI55
names: Similarity
messages: Belongs to the malate synthase family.

1064539:Sp245p RS00805
gene id: 1064539:Sp245p_RS00805
uniprot id: G8AGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1064539:Sp245p RS33360
gene id: 1064539:Sp245p_RS33360
uniprot id: G8AMX6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1064539:Sp245p RS22570
gene id: 1064539:Sp245p_RS22570
uniprot id: G8AY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1064539:Sp245p RS13760
gene id: 1064539:Sp245p_RS13760
uniprot id: G8AIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1064539:Sp245p RS15390
gene id: 1064539:Sp245p_RS15390
uniprot id: G8APU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1064539:Sp245p RS12600
gene id: 1064539:Sp245p_RS12600
uniprot id: G8AJ57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS15940
gene id: 1064539:Sp245p_RS15940
uniprot id: G8AQ72
names: Similarity
messages: Belongs to the virb1 family.

1064539:Sp245p RS33195
gene id: 1064539:Sp245p_RS33195
uniprot id: G8AZ33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS30555
gene id: 1064539:Sp245p_RS30555
uniprot id: G8AUF6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS07280
gene id: 1064539:Sp245p_RS07280
uniprot id: G8AMB3
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS05680
gene id: 1064539:Sp245p_RS05680
uniprot id: G8AEM9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1064539:Sp245p RS04800
gene id: 1064539:Sp245p_RS04800
uniprot id: G8AFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1064539:Sp245p RS02005
gene id: 1064539:Sp245p_RS02005
uniprot id: G8AF56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1064539:Sp245p RS33270
gene id: 1064539:Sp245p_RS33270
uniprot id: G8AZ52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS22940
gene id: 1064539:Sp245p_RS22940
uniprot id: G8AXY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS23740
gene id: 1064539:Sp245p_RS23740
uniprot id: G8AXE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS09390
gene id: 1064539:Sp245p_RS09390
uniprot id: G8AL91
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1064539:Sp245p RS32860
gene id: 1064539:Sp245p_RS32860
uniprot id: G8AYV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05830
gene id: 1064539:Sp245p_RS05830
uniprot id: G8ANK7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1064539:Sp245p RS15145
gene id: 1064539:Sp245p_RS15145
uniprot id: G8APP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1064539:Sp245p RS05185
gene id: 1064539:Sp245p_RS05185
uniprot id: G8AEY8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1064539:Sp245p RS17650
gene id: 1064539:Sp245p_RS17650
uniprot id: G8ARC5
names: Similarity
messages: Belongs to the virb1 family.

1064539:Sp245p RS06095
gene id: 1064539:Sp245p_RS06095
uniprot id: G8ANE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1064539:Sp245p RS18075
gene id: 1064539:Sp245p_RS18075
uniprot id: G8ARM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS33820
gene id: 1064539:Sp245p_RS33820
uniprot id: G8AZF4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1064539:Sp245p RS31915
gene id: 1064539:Sp245p_RS31915
uniprot id: G8B0B5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1064539:Sp245p RS04945
gene id: 1064539:Sp245p_RS04945
uniprot id: G8AFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1064539:Sp245p RS11885
gene id: 1064539:Sp245p_RS11885
uniprot id: G8AJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS11635
gene id: 1064539:Sp245p_RS11635
uniprot id: G8AJT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1064539:Sp245p RS03245
gene id: 1064539:Sp245p_RS03245
uniprot id: G8AHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS02135
gene id: 1064539:Sp245p_RS02135
uniprot id: G8AF26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS01640
gene id: 1064539:Sp245p_RS01640
uniprot id: G8AFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1064539:Sp245p RS05660
gene id: 1064539:Sp245p_RS05660
uniprot id: G8AEN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1064539:Sp245p RS20865
gene id: 1064539:Sp245p_RS20865
uniprot id: G8ATH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Membrane

1064539:Sp245p RS06975
gene id: 1064539:Sp245p_RS06975
uniprot id: G8AM39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1064539:Sp245p RS04870
gene id: 1064539:Sp245p_RS04870
uniprot id: G8AFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1064539:Sp245p RS03125
gene id: 1064539:Sp245p_RS03125
uniprot id: G8AHU6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1064539:Sp245p RS06275
gene id: 1064539:Sp245p_RS06275
uniprot id: G8ANA7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1064539:Sp245p RS10075
gene id: 1064539:Sp245p_RS10075
uniprot id: G8AKU3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1064539:Sp245p RS02855
gene id: 1064539:Sp245p_RS02855
uniprot id: G8AE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS21165
gene id: 1064539:Sp245p_RS21165
uniprot id: G8ATP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1064539:Sp245p RS29510
gene id: 1064539:Sp245p_RS29510
uniprot id: G8AWC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1064539:Sp245p RS04220
gene id: 1064539:Sp245p_RS04220
uniprot id: G8AGL3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1064539:Sp245p RS03195
gene id: 1064539:Sp245p_RS03195
uniprot id: G8AHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1064539:Sp245p RS24690
gene id: 1064539:Sp245p_RS24690
uniprot id: G8AWS5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS17440
gene id: 1064539:Sp245p_RS17440
uniprot id: G8AR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS32880
gene id: 1064539:Sp245p_RS32880
uniprot id: G8AYW2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS33975
gene id: 1064539:Sp245p_RS33975
uniprot id: G8AZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS02300
gene id: 1064539:Sp245p_RS02300
uniprot id: G8AEI1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1064539:Sp245p RS22225
gene id: 1064539:Sp245p_RS22225
uniprot id: G8AP72
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1064539:Sp245p RS07350
gene id: 1064539:Sp245p_RS07350
uniprot id: G8AMC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1064539:Sp245p RS01205
gene id: 1064539:Sp245p_RS01205
uniprot id: G8AG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1064539:Sp245p RS13110
gene id: 1064539:Sp245p_RS13110
uniprot id: G8AIU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1064539:Sp245p RS12325
gene id: 1064539:Sp245p_RS12325
uniprot id: G8AJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS18555
gene id: 1064539:Sp245p_RS18555
uniprot id: G8ARY7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1064539:Sp245p RS02820
gene id: 1064539:Sp245p_RS02820
uniprot id: G8AE67
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1064539:Sp245p RS22130
gene id: 1064539:Sp245p_RS22130
uniprot id: G8AP43
names: Subcellular Location Annotation
messages: Secreted

1064539:Sp245p RS33305
gene id: 1064539:Sp245p_RS33305
uniprot id: G8AZ58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1064539:Sp245p RS18105
gene id: 1064539:Sp245p_RS18105
uniprot id: G8ARM8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1064539:Sp245p RS06810
gene id: 1064539:Sp245p_RS06810
uniprot id: G8AMY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS15480
gene id: 1064539:Sp245p_RS15480
uniprot id: G8APW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1064539:Sp245p RS12570
gene id: 1064539:Sp245p_RS12570
uniprot id: G8AJ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS24180
gene id: 1064539:Sp245p_RS24180
uniprot id: G8AX40
names: Similarity
messages: Belongs to the PrpF family.

1064539:Sp245p RS00640
gene id: 1064539:Sp245p_RS00640
uniprot id: G8AGY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1064539:Sp245p RS00440
gene id: 1064539:Sp245p_RS00440
uniprot id: G8AH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS21895
gene id: 1064539:Sp245p_RS21895
uniprot id: G8ANZ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS13130
gene id: 1064539:Sp245p_RS13130
uniprot id: G8AIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS19980
gene id: 1064539:Sp245p_RS19980
uniprot id: G8ASX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS23215
gene id: 1064539:Sp245p_RS23215
uniprot id: G8AXR6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS24230
gene id: 1064539:Sp245p_RS24230
uniprot id: G8AX30
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

1064539:Sp245p RS12040
gene id: 1064539:Sp245p_RS12040
uniprot id: G8AJJ1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1064539:Sp245p RS23120
gene id: 1064539:Sp245p_RS23120
uniprot id: G8AXT9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS17245
gene id: 1064539:Sp245p_RS17245
uniprot id: G8AR31
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1064539:Sp245p RS04830
gene id: 1064539:Sp245p_RS04830
uniprot id: G8AFN7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS00405
gene id: 1064539:Sp245p_RS00405
uniprot id: G8AH46
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1064539:Sp245p RS13140
gene id: 1064539:Sp245p_RS13140
uniprot id: G8AIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1064539:Sp245p RS20000
gene id: 1064539:Sp245p_RS20000
uniprot id: G8ASX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1064539:Sp245p RS32255
gene id: 1064539:Sp245p_RS32255
uniprot id: G8B0H3
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1064539:Sp245p RS12130
gene id: 1064539:Sp245p_RS12130
uniprot id: G8AJG9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1064539:Sp245p RS02620
gene id: 1064539:Sp245p_RS02620
uniprot id: G8AEB0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1064539:Sp245p RS30395
gene id: 1064539:Sp245p_RS30395
uniprot id: G8AUC5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1064539:Sp245p RS31760
gene id: 1064539:Sp245p_RS31760
uniprot id: G8B078
names: Similarity
messages: Belongs to the virb1 family.

1064539:Sp245p RS07880
gene id: 1064539:Sp245p_RS07880
uniprot id: G8AMQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1064539:Sp245p RS17315
gene id: 1064539:Sp245p_RS17315
uniprot id: G8AR51
names: Similarity
messages: Belongs to the threonine synthase family.

1064539:Sp245p RS02310
gene id: 1064539:Sp245p_RS02310
uniprot id: G8AEH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS32925
gene id: 1064539:Sp245p_RS32925
uniprot id: G8AYX2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1064539:Sp245p RS09475
gene id: 1064539:Sp245p_RS09475
uniprot id: G8AL72
names: Similarity
messages: Belongs to the CutA family.

1064539:Sp245p RS11735
gene id: 1064539:Sp245p_RS11735
uniprot id: G8AJR0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1064539:Sp245p RS22955
gene id: 1064539:Sp245p_RS22955
uniprot id: G8AXX6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1064539:Sp245p RS11165
gene id: 1064539:Sp245p_RS11165
uniprot id: G8AK42
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS17510
gene id: 1064539:Sp245p_RS17510
uniprot id: G8AR95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1064539:Sp245p RS27100
gene id: 1064539:Sp245p_RS27100
uniprot id: G8AUN8
names: Similarity
messages: Belongs to the ParB family.

1064539:Sp245p RS21925
gene id: 1064539:Sp245p_RS21925
uniprot id: G8ANZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06520
gene id: 1064539:Sp245p_RS06520
uniprot id: G8AN50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1064539:Sp245p RS08525
gene id: 1064539:Sp245p_RS08525
uniprot id: G8ALT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS01725
gene id: 1064539:Sp245p_RS01725
uniprot id: G8AFC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1064539:Sp245p RS20110
gene id: 1064539:Sp245p_RS20110
uniprot id: G8AT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1064539:Sp245p RS08895
gene id: 1064539:Sp245p_RS08895
uniprot id: G8ALJ9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS22510
gene id: 1064539:Sp245p_RS22510
uniprot id: G8AY76
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23920
gene id: 1064539:Sp245p_RS23920
uniprot id: G8AXA0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS10665
gene id: 1064539:Sp245p_RS10665
uniprot id: G8AKG2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1064539:Sp245p RS28640
gene id: 1064539:Sp245p_RS28640
uniprot id: G8AVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1064539:Sp245p RS19135
gene id: 1064539:Sp245p_RS19135
uniprot id: G8ASC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1064539:Sp245p RS16915
gene id: 1064539:Sp245p_RS16915
uniprot id: G8AQW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS25385
gene id: 1064539:Sp245p_RS25385
uniprot id: G8AYN7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1064539:Sp245p RS22535
gene id: 1064539:Sp245p_RS22535
uniprot id: G8AY70
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1064539:Sp245p RS08060
gene id: 1064539:Sp245p_RS08060
uniprot id: G8AMT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1064539:Sp245p RS20840
gene id: 1064539:Sp245p_RS20840
uniprot id: G8ATH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1064539:Sp245p RS04335
gene id: 1064539:Sp245p_RS04335
uniprot id: G8AGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS27485
gene id: 1064539:Sp245p_RS27485
uniprot id: G8AUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1064539:Sp245p RS09115
gene id: 1064539:Sp245p_RS09115
uniprot id: G8ALE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1064539:Sp245p RS25405
gene id: 1064539:Sp245p_RS25405
uniprot id: G8AYN3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1064539:Sp245p RS24850
gene id: 1064539:Sp245p_RS24850
uniprot id: G8AWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS20325
gene id: 1064539:Sp245p_RS20325
uniprot id: G8AT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1064539:Sp245p RS09120
gene id: 1064539:Sp245p_RS09120
uniprot id: G8ALE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1064539:Sp245p RS02830
gene id: 1064539:Sp245p_RS02830
uniprot id: G8AE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS09180
gene id: 1064539:Sp245p_RS09180
uniprot id: G8ALD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS30340
gene id: 1064539:Sp245p_RS30340
uniprot id: G8AUB3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1064539:Sp245p RS21815
gene id: 1064539:Sp245p_RS21815
uniprot id: G8ANX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1064539:Sp245p RS23585
gene id: 1064539:Sp245p_RS23585
uniprot id: G8AXI2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS11515
gene id: 1064539:Sp245p_RS11515
uniprot id: G8AJV9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23175
gene id: 1064539:Sp245p_RS23175
uniprot id: G8AXS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1064539:Sp245p RS17620
gene id: 1064539:Sp245p_RS17620
uniprot id: G8ARB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS07680
gene id: 1064539:Sp245p_RS07680
uniprot id: G8AMK0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1064539:Sp245p RS03045
gene id: 1064539:Sp245p_RS03045
uniprot id: G8AIC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1064539:Sp245p RS17585
gene id: 1064539:Sp245p_RS17585
uniprot id: G8ARB1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1064539:Sp245p RS29835
gene id: 1064539:Sp245p_RS29835
uniprot id: G8ATZ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS23720
gene id: 1064539:Sp245p_RS23720
uniprot id: G8AXE5
names: Similarity
messages: Belongs to the transposase 7 family.

1064539:Sp245p RS26570
gene id: 1064539:Sp245p_RS26570
uniprot id: G8B196
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1064539:Sp245p RS19500
gene id: 1064539:Sp245p_RS19500
uniprot id: G8ASM0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS22175
gene id: 1064539:Sp245p_RS22175
uniprot id: G8AP56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS06915
gene id: 1064539:Sp245p_RS06915
uniprot id: G8AM26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1064539:Sp245p RS26585
gene id: 1064539:Sp245p_RS26585
uniprot id: G8B193
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS21750
gene id: 1064539:Sp245p_RS21750
uniprot id: G8ANW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1064539:Sp245p RS01710
gene id: 1064539:Sp245p_RS01710
uniprot id: G8AFC3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1064539:Sp245p RS16630
gene id: 1064539:Sp245p_RS16630
uniprot id: G8AQP3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1064539:Sp245p RS08940
gene id: 1064539:Sp245p_RS08940
uniprot id: G8ALI9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS29725
gene id: 1064539:Sp245p_RS29725
uniprot id: G8ATW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1064539:Sp245p RS09730
gene id: 1064539:Sp245p_RS09730
uniprot id: G8AL14
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1064539:Sp245p RS02790
gene id: 1064539:Sp245p_RS02790
uniprot id: G8AE73
names: Similarity
messages: Belongs to the UPF0434 family.

1064539:Sp245p RS09995
gene id: 1064539:Sp245p_RS09995
uniprot id: G8AKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS02265
gene id: 1064539:Sp245p_RS02265
uniprot id: G8AEI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1064539:Sp245p RS02205
gene id: 1064539:Sp245p_RS02205
uniprot id: G8AEK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1064539:Sp245p RS32655
gene id: 1064539:Sp245p_RS32655
uniprot id: G8B0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1064539:Sp245p RS01285
gene id: 1064539:Sp245p_RS01285
uniprot id: G8AG32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS24290
gene id: 1064539:Sp245p_RS24290
uniprot id: G8AX16
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.

1064539:Sp245p RS03135
gene id: 1064539:Sp245p_RS03135
uniprot id: G8AHU4
names: Similarity
messages: Belongs to the LOG family.

1064539:Sp245p RS16745
gene id: 1064539:Sp245p_RS16745
uniprot id: G8AQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1064539:Sp245p RS25110
gene id: 1064539:Sp245p_RS25110
uniprot id: G8AWH6
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1064539:Sp245p RS18080
gene id: 1064539:Sp245p_RS18080
uniprot id: G8ARM2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1064539:Sp245p RS28685
gene id: 1064539:Sp245p_RS28685
uniprot id: G8AVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS30520
gene id: 1064539:Sp245p_RS30520
uniprot id: G8AUE7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS19160
gene id: 1064539:Sp245p_RS19160
uniprot id: G8ASD8
names: Similarity
messages: Belongs to the universal stress protein A family.

1064539:Sp245p RS08770
gene id: 1064539:Sp245p_RS08770
uniprot id: G8ALM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1064539:Sp245p RS18275
gene id: 1064539:Sp245p_RS18275
uniprot id: G8ARR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1064539:Sp245p RS01220
gene id: 1064539:Sp245p_RS01220
uniprot id: G8AG47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1064539:Sp245p RS13200
gene id: 1064539:Sp245p_RS13200
uniprot id: G8AIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1064539:Sp245p RS06540
gene id: 1064539:Sp245p_RS06540
uniprot id: G8AN45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1064539:Sp245p RS17695
gene id: 1064539:Sp245p_RS17695
uniprot id: G8ARD6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS11640
gene id: 1064539:Sp245p_RS11640
uniprot id: G8AJS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1064539:Sp245p RS27840
gene id: 1064539:Sp245p_RS27840
uniprot id: G8AV77
names: Similarity
messages: Belongs to the PrpF family.

1064539:Sp245p RS16820
gene id: 1064539:Sp245p_RS16820
uniprot id: G8AQU1
names: Similarity
messages: Belongs to the HesB/IscA family.

1064539:Sp245p RS11870
gene id: 1064539:Sp245p_RS11870
uniprot id: G8AJN0
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1064539:Sp245p RS34050
gene id: 1064539:Sp245p_RS34050
uniprot id: G8AZK3
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1064539:Sp245p RS05980
gene id: 1064539:Sp245p_RS05980
uniprot id: G8ANH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1064539:Sp245p RS07270
gene id: 1064539:Sp245p_RS07270
uniprot id: G8AMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1064539:Sp245p RS17550
gene id: 1064539:Sp245p_RS17550
uniprot id: G8ARA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1064539:Sp245p RS24685
gene id: 1064539:Sp245p_RS24685
uniprot id: G8AWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS32435
gene id: 1064539:Sp245p_RS32435
uniprot id: G8B0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1064539:Sp245p RS00945
gene id: 1064539:Sp245p_RS00945
uniprot id: G8AGA8
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS03965
gene id: 1064539:Sp245p_RS03965
uniprot id: G8AGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1064539:Sp245p RS13530
gene id: 1064539:Sp245p_RS13530
uniprot id: G8AIJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS05770
gene id: 1064539:Sp245p_RS05770
uniprot id: G8AEK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1064539:Sp245p RS13115
gene id: 1064539:Sp245p_RS13115
uniprot id: G8AIU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1064539:Sp245p RS18550
gene id: 1064539:Sp245p_RS18550
uniprot id: G8ARY6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS24660
gene id: 1064539:Sp245p_RS24660
uniprot id: G8AWT2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS14155
gene id: 1064539:Sp245p_RS14155
uniprot id: G8AI12
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1064539:Sp245p RS11025
gene id: 1064539:Sp245p_RS11025
uniprot id: G8AK75
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1064539:Sp245p RS14850
gene id: 1064539:Sp245p_RS14850
uniprot id: G8API2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS08820
gene id: 1064539:Sp245p_RS08820
uniprot id: G8ALL5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1064539:Sp245p RS13320
gene id: 1064539:Sp245p_RS13320
uniprot id: G8AIP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS31435
gene id: 1064539:Sp245p_RS31435
uniprot id: G8B010
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS01585
gene id: 1064539:Sp245p_RS01585
uniprot id: G8AFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1064539:Sp245p RS01525
gene id: 1064539:Sp245p_RS01525
uniprot id: G8AFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1064539:Sp245p RS01885
gene id: 1064539:Sp245p_RS01885
uniprot id: G8AF86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS03025
gene id: 1064539:Sp245p_RS03025
uniprot id: G8AID2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1064539:Sp245p RS01100
gene id: 1064539:Sp245p_RS01100
uniprot id: G8AG74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1064539:Sp245p RS19125
gene id: 1064539:Sp245p_RS19125
uniprot id: G8ASC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1064539:Sp245p RS29050
gene id: 1064539:Sp245p_RS29050
uniprot id: G8AW15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS24825
gene id: 1064539:Sp245p_RS24825
uniprot id: G8AWP4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS04900
gene id: 1064539:Sp245p_RS04900
uniprot id: G8AFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1064539:Sp245p RS11030
gene id: 1064539:Sp245p_RS11030
uniprot id: G8AK74
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1064539:Sp245p RS00185
gene id: 1064539:Sp245p_RS00185
uniprot id: G8AH90
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1064539:Sp245p RS26610
gene id: 1064539:Sp245p_RS26610
uniprot id: G8B188
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS11055
gene id: 1064539:Sp245p_RS11055
uniprot id: G8AK69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS08755
gene id: 1064539:Sp245p_RS08755
uniprot id: G8ALM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1064539:Sp245p RS33430
gene id: 1064539:Sp245p_RS33430
uniprot id: G8AZ66
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1064539:Sp245p RS32145
gene id: 1064539:Sp245p_RS32145
uniprot id: G8B0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1064539:Sp245p RS13185
gene id: 1064539:Sp245p_RS13185
uniprot id: G8AIS7
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1064539:Sp245p RS19635
gene id: 1064539:Sp245p_RS19635
uniprot id: G8ASP7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1064539:Sp245p RS06690
gene id: 1064539:Sp245p_RS06690
uniprot id: G8AN14
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1064539:Sp245p RS07365
gene id: 1064539:Sp245p_RS07365
uniprot id: G8AMD2
names: Similarity
messages: Belongs to the MlaA family.

1064539:Sp245p RS15185
gene id: 1064539:Sp245p_RS15185
uniprot id: G8APQ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS14515
gene id: 1064539:Sp245p_RS14515
uniprot id: G8APB4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1064539:Sp245p RS13670
gene id: 1064539:Sp245p_RS13670
uniprot id: G8AIC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS08790
gene id: 1064539:Sp245p_RS08790
uniprot id: G8ALM0
names: Similarity
messages: Belongs to the fabD family.

1064539:Sp245p RS03960
gene id: 1064539:Sp245p_RS03960
uniprot id: G8AGS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1064539:Sp245p RS33830
gene id: 1064539:Sp245p_RS33830
uniprot id: G8AZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS00255
gene id: 1064539:Sp245p_RS00255
uniprot id: G8AH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06725
gene id: 1064539:Sp245p_RS06725
uniprot id: G8AN07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1064539:Sp245p RS21875
gene id: 1064539:Sp245p_RS21875
uniprot id: G8ANY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS20195
gene id: 1064539:Sp245p_RS20195
uniprot id: G8AT23
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1064539:Sp245p RS19085
gene id: 1064539:Sp245p_RS19085
uniprot id: G8ASB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1064539:Sp245p RS06545
gene id: 1064539:Sp245p_RS06545
uniprot id: G8AN44
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1064539:Sp245p RS20145
gene id: 1064539:Sp245p_RS20145
uniprot id: G8AT14
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS09720
gene id: 1064539:Sp245p_RS09720
uniprot id: G8AL17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS13250
gene id: 1064539:Sp245p_RS13250
uniprot id: G8AIR1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1064539:Sp245p RS09885
gene id: 1064539:Sp245p_RS09885
uniprot id: G8AKY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1064539:Sp245p RS24050
gene id: 1064539:Sp245p_RS24050
uniprot id: G8AX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1064539:Sp245p RS24465
gene id: 1064539:Sp245p_RS24465
uniprot id: G8AWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS05760
gene id: 1064539:Sp245p_RS05760
uniprot id: G8AEL1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1064539:Sp245p RS17445
gene id: 1064539:Sp245p_RS17445
uniprot id: G8AR82
names: Similarity
messages: Belongs to the UxaA family.

1064539:Sp245p RS12670
gene id: 1064539:Sp245p_RS12670
uniprot id: G8AJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1064539:Sp245p RS30515
gene id: 1064539:Sp245p_RS30515
uniprot id: G8AUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1064539:Sp245p RS26960
gene id: 1064539:Sp245p_RS26960
uniprot id: G8AUK4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1064539:Sp245p RS29370
gene id: 1064539:Sp245p_RS29370
uniprot id: G8AW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS12385
gene id: 1064539:Sp245p_RS12385
uniprot id: G8AJA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS13035
gene id: 1064539:Sp245p_RS13035
uniprot id: G8AIW0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS27130
gene id: 1064539:Sp245p_RS27130
uniprot id: G8AUP5
names: Similarity
messages: Belongs to the hyi family.

1064539:Sp245p RS32575
gene id: 1064539:Sp245p_RS32575
uniprot id: G8B0K7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS00145
gene id: 1064539:Sp245p_RS00145
uniprot id: G8AH99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS17460
gene id: 1064539:Sp245p_RS17460
uniprot id: G8AR85
names: Similarity
messages: Belongs to the peptidase S41A family.

1064539:Sp245p RS04340
gene id: 1064539:Sp245p_RS04340
uniprot id: G8AGI6
names: Similarity
messages: Belongs to the DinB family.

1064539:Sp245p RS11905
gene id: 1064539:Sp245p_RS11905
uniprot id: G8AJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1064539:Sp245p RS07850
gene id: 1064539:Sp245p_RS07850
uniprot id: G8AMP3
names: Similarity
messages: Belongs to the ros/MucR family.

1064539:Sp245p RS35785
gene id: 1064539:Sp245p_RS35785
uniprot id: G8AQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1064539:Sp245p RS10145
gene id: 1064539:Sp245p_RS10145
uniprot id: G8AKS7
names: Similarity
messages: Belongs to the PhzF family.

1064539:Sp245p RS02280
gene id: 1064539:Sp245p_RS02280
uniprot id: G8AEI5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1064539:Sp245p RS05805
gene id: 1064539:Sp245p_RS05805
uniprot id: G8ANL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1064539:Sp245p RS30205
gene id: 1064539:Sp245p_RS30205
uniprot id: G8AU80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS06925
gene id: 1064539:Sp245p_RS06925
uniprot id: G8AM28
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1064539:Sp245p RS06430
gene id: 1064539:Sp245p_RS06430
uniprot id: G8AN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1064539:Sp245p RS08160
gene id: 1064539:Sp245p_RS08160
uniprot id: G8AMW7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1064539:Sp245p RS28105
gene id: 1064539:Sp245p_RS28105
uniprot id: G8AVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS34310
gene id: 1064539:Sp245p_RS34310
uniprot id: G8AZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS15700
gene id: 1064539:Sp245p_RS15700
uniprot id: G8AQ17
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1064539:Sp245p RS07115
gene id: 1064539:Sp245p_RS07115
uniprot id: G8AM70
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

1064539:Sp245p RS33015
gene id: 1064539:Sp245p_RS33015
uniprot id: G8AYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1064539:Sp245p RS03280
gene id: 1064539:Sp245p_RS03280
uniprot id: G8AHQ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1064539:Sp245p RS08920
gene id: 1064539:Sp245p_RS08920
uniprot id: G8ALJ3
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS27805
gene id: 1064539:Sp245p_RS27805
uniprot id: G8AV68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1064539:Sp245p RS18545
gene id: 1064539:Sp245p_RS18545
uniprot id: G8ARY4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1064539:Sp245p RS02375
gene id: 1064539:Sp245p_RS02375
uniprot id: G8AEG4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1064539:Sp245p RS13430
gene id: 1064539:Sp245p_RS13430
uniprot id: G8AIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS21160
gene id: 1064539:Sp245p_RS21160
uniprot id: G8ATN9
names: Similarity
messages: Belongs to the HypD family.

1064539:Sp245p RS18565
gene id: 1064539:Sp245p_RS18565
uniprot id: G8ARY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS25200
gene id: 1064539:Sp245p_RS25200
uniprot id: G8AWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS08795
gene id: 1064539:Sp245p_RS08795
uniprot id: G8ALL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1064539:Sp245p RS17950
gene id: 1064539:Sp245p_RS17950
uniprot id: G8ARJ5
names: Similarity
messages: Belongs to the GST superfamily.

1064539:Sp245p RS04810
gene id: 1064539:Sp245p_RS04810
uniprot id: G8AFP1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1064539:Sp245p RS34615
gene id: 1064539:Sp245p_RS34615
uniprot id: G8AZX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS29505
gene id: 1064539:Sp245p_RS29505
uniprot id: G8AWC8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1064539:Sp245p RS15030
gene id: 1064539:Sp245p_RS15030
uniprot id: G8APL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1064539:Sp245p RS22560
gene id: 1064539:Sp245p_RS22560
uniprot id: G8AY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1064539:Sp245p RS01375
gene id: 1064539:Sp245p_RS01375
uniprot id: G8AG14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1064539:Sp245p RS15160
gene id: 1064539:Sp245p_RS15160
uniprot id: G8APP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS09160
gene id: 1064539:Sp245p_RS09160
uniprot id: G8ALD7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1064539:Sp245p RS10080
gene id: 1064539:Sp245p_RS10080
uniprot id: G8AKU1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1064539:Sp245p RS03890
gene id: 1064539:Sp245p_RS03890
uniprot id: G8AGU5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS33145
gene id: 1064539:Sp245p_RS33145
uniprot id: G8AZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1064539:Sp245p RS11730
gene id: 1064539:Sp245p_RS11730
uniprot id: G8AJR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1064539:Sp245p RS00630
gene id: 1064539:Sp245p_RS00630
uniprot id: G8AGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1064539:Sp245p RS11575
gene id: 1064539:Sp245p_RS11575
uniprot id: G8AJU4
names: Similarity
messages: Belongs to the NifZ family.

1064539:Sp245p RS18665
gene id: 1064539:Sp245p_RS18665
uniprot id: G8AS09
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1064539:Sp245p RS30065
gene id: 1064539:Sp245p_RS30065
uniprot id: G8AU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1064539:Sp245p RS18255
gene id: 1064539:Sp245p_RS18255
uniprot id: G8ARR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1064539:Sp245p RS30570
gene id: 1064539:Sp245p_RS30570
uniprot id: G8AUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1064539:Sp245p RS04845
gene id: 1064539:Sp245p_RS04845
uniprot id: G8AFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1064539:Sp245p RS07285
gene id: 1064539:Sp245p_RS07285
uniprot id: G8AMB4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1064539:Sp245p RS10590
gene id: 1064539:Sp245p_RS10590
uniprot id: G8AKH9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS25345
gene id: 1064539:Sp245p_RS25345
uniprot id: G8AYP6
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

1064539:Sp245p RS29880
gene id: 1064539:Sp245p_RS29880
uniprot id: G8AU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1064539:Sp245p RS22325
gene id: 1064539:Sp245p_RS22325
uniprot id: G8AP98
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS11910
gene id: 1064539:Sp245p_RS11910
uniprot id: G8AJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1064539:Sp245p RS23625
gene id: 1064539:Sp245p_RS23625
uniprot id: G8AXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1064539:Sp245p RS28250
gene id: 1064539:Sp245p_RS28250
uniprot id: G8AVH4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS23695
gene id: 1064539:Sp245p_RS23695
uniprot id: G8AXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1064539:Sp245p RS16140
gene id: 1064539:Sp245p_RS16140
uniprot id: G8AQC1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1064539:Sp245p RS27280
gene id: 1064539:Sp245p_RS27280
uniprot id: G8AUS9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS01900
gene id: 1064539:Sp245p_RS01900
uniprot id: G8AF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS13155
gene id: 1064539:Sp245p_RS13155
uniprot id: G8AIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1064539:Sp245p RS13700
gene id: 1064539:Sp245p_RS13700
uniprot id: G8AIB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1064539:Sp245p RS00395
gene id: 1064539:Sp245p_RS00395
uniprot id: G8AH49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1064539:Sp245p RS07630
gene id: 1064539:Sp245p_RS07630
uniprot id: G8AMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1064539:Sp245p RS29660
gene id: 1064539:Sp245p_RS29660
uniprot id: G8ATU7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS08995
gene id: 1064539:Sp245p_RS08995
uniprot id: G8ALH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1064539:Sp245p RS30305
gene id: 1064539:Sp245p_RS30305
uniprot id: G8AUA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05870
gene id: 1064539:Sp245p_RS05870
uniprot id: G8ANJ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1064539:Sp245p RS24265
gene id: 1064539:Sp245p_RS24265
uniprot id: G8AX22
names: Similarity
messages: Belongs to the HIBADH-related family.

1064539:Sp245p RS07905
gene id: 1064539:Sp245p_RS07905
uniprot id: G8AMQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1064539:Sp245p RS19735
gene id: 1064539:Sp245p_RS19735
uniprot id: G8ASR9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09545
gene id: 1064539:Sp245p_RS09545
uniprot id: G8AL56
names: Similarity
messages: Belongs to the ArsC family.

1064539:Sp245p RS04255
gene id: 1064539:Sp245p_RS04255
uniprot id: G8AGK5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1064539:Sp245p RS13105
gene id: 1064539:Sp245p_RS13105
uniprot id: G8AIU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1064539:Sp245p RS01850
gene id: 1064539:Sp245p_RS01850
uniprot id: G8AF93
names: Subcellular Location Annotation
messages: Cytoplasm

1064539:Sp245p RS00890
gene id: 1064539:Sp245p_RS00890
uniprot id: G8AGB9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1064539:Sp245p RS31880
gene id: 1064539:Sp245p_RS31880
uniprot id: G8B0A9
names: Similarity
messages: Belongs to the TPP enzyme family.

1064539:Sp245p RS13080
gene id: 1064539:Sp245p_RS13080
uniprot id: G8AIU9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS13055
gene id: 1064539:Sp245p_RS13055
uniprot id: G8AIV6
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

1064539:Sp245p RS16725
gene id: 1064539:Sp245p_RS16725
uniprot id: G8AQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1064539:Sp245p RS20680
gene id: 1064539:Sp245p_RS20680
uniprot id: G8ATD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1064539:Sp245p RS32915
gene id: 1064539:Sp245p_RS32915
uniprot id: G8AYX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1064539:Sp245p RS23750
gene id: 1064539:Sp245p_RS23750
uniprot id: G8AXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1064539:Sp245p RS07795
gene id: 1064539:Sp245p_RS07795
uniprot id: G8AMN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1064539:Sp245p RS01565
gene id: 1064539:Sp245p_RS01565
uniprot id: G8AFF7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1064539:Sp245p RS29890
gene id: 1064539:Sp245p_RS29890
uniprot id: G8AU04
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS04135
gene id: 1064539:Sp245p_RS04135
uniprot id: G8AGN2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18380
gene id: 1064539:Sp245p_RS18380
uniprot id: G8ART9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1064539:Sp245p RS11220
gene id: 1064539:Sp245p_RS11220
uniprot id: G8AK29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS23285
gene id: 1064539:Sp245p_RS23285
uniprot id: G8AXQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS05775
gene id: 1064539:Sp245p_RS05775
uniprot id: G8AEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1064539:Sp245p RS15485
gene id: 1064539:Sp245p_RS15485
uniprot id: G8APX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1064539:Sp245p RS28940
gene id: 1064539:Sp245p_RS28940
uniprot id: G8AVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1064539:Sp245p RS05330
gene id: 1064539:Sp245p_RS05330
uniprot id: G8AEV9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS33280
gene id: 1064539:Sp245p_RS33280
uniprot id: G8AZ53
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1064539:Sp245p RS09145
gene id: 1064539:Sp245p_RS09145
uniprot id: G8ALE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS09910
gene id: 1064539:Sp245p_RS09910
uniprot id: G8AKX5
names: Similarity
messages: Belongs to the RelE toxin family.

1064539:Sp245p RS24480
gene id: 1064539:Sp245p_RS24480
uniprot id: G8AWX1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS09075
gene id: 1064539:Sp245p_RS09075
uniprot id: G8ALF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1064539:Sp245p RS13915
gene id: 1064539:Sp245p_RS13915
uniprot id: G8AI67
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1064539:Sp245p RS02515
gene id: 1064539:Sp245p_RS02515
uniprot id: G8AED3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS03970
gene id: 1064539:Sp245p_RS03970
uniprot id: G8AGS5
names: Similarity
messages: Belongs to the carbamate kinase family.

1064539:Sp245p RS20550
gene id: 1064539:Sp245p_RS20550
uniprot id: G8ATA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1064539:Sp245p RS29950
gene id: 1064539:Sp245p_RS29950
uniprot id: G8AU18
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1064539:Sp245p RS05135
gene id: 1064539:Sp245p_RS05135
uniprot id: G8AF00
names: Similarity
messages: Belongs to the YkuD family.

1064539:Sp245p RS06840
gene id: 1064539:Sp245p_RS06840
uniprot id: G8AM10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1064539:Sp245p RS06295
gene id: 1064539:Sp245p_RS06295
uniprot id: G8ANA2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1064539:Sp245p RS17020
gene id: 1064539:Sp245p_RS17020
uniprot id: G8AQY4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS07780
gene id: 1064539:Sp245p_RS07780
uniprot id: G8AMM9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS34325
gene id: 1064539:Sp245p_RS34325
uniprot id: G8AZR9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1064539:Sp245p RS22080
gene id: 1064539:Sp245p_RS22080
uniprot id: G8AP30
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1064539:Sp245p RS02185
gene id: 1064539:Sp245p_RS02185
uniprot id: G8AF16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1064539:Sp245p RS15675
gene id: 1064539:Sp245p_RS15675
uniprot id: G8AQ12
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1064539:Sp245p RS01485
gene id: 1064539:Sp245p_RS01485
uniprot id: G8AFH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1064539:Sp245p RS04625
gene id: 1064539:Sp245p_RS04625
uniprot id: G8AFU0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS00480
gene id: 1064539:Sp245p_RS00480
uniprot id: G8AH25
names: Cofactor
messages: Can also use Mn(2+) ion.

1064539:Sp245p RS14295
gene id: 1064539:Sp245p_RS14295
uniprot id: G8AHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1064539:Sp245p RS30440
gene id: 1064539:Sp245p_RS30440
uniprot id: G8AUD0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS33785
gene id: 1064539:Sp245p_RS33785
uniprot id: G8AZE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1064539:Sp245p RS32125
gene id: 1064539:Sp245p_RS32125
uniprot id: G8B0E4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1064539:Sp245p RS24585
gene id: 1064539:Sp245p_RS24585
uniprot id: G8AWU9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS24640
gene id: 1064539:Sp245p_RS24640
uniprot id: G8AWT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS04260
gene id: 1064539:Sp245p_RS04260
uniprot id: G8AGK4
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS10685
gene id: 1064539:Sp245p_RS10685
uniprot id: G8AKF8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1064539:Sp245p RS05050
gene id: 1064539:Sp245p_RS05050
uniprot id: G8AFI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1064539:Sp245p RS02235
gene id: 1064539:Sp245p_RS02235
uniprot id: G8AEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS24960
gene id: 1064539:Sp245p_RS24960
uniprot id: G8AWK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS03240
gene id: 1064539:Sp245p_RS03240
uniprot id: G8AHR5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS25170
gene id: 1064539:Sp245p_RS25170
uniprot id: G8AWG2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS34390
gene id: 1064539:Sp245p_RS34390
uniprot id: G8AZT3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS26010
gene id: 1064539:Sp245p_RS26010
uniprot id: G8AYA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1064539:Sp245p RS09705
gene id: 1064539:Sp245p_RS09705
uniprot id: G8AL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1064539:Sp245p RS24860
gene id: 1064539:Sp245p_RS24860
uniprot id: G8AWN6
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS07855
gene id: 1064539:Sp245p_RS07855
uniprot id: G8AMP6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1064539:Sp245p RS01520
gene id: 1064539:Sp245p_RS01520
uniprot id: G8AFG7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27040
gene id: 1064539:Sp245p_RS27040
uniprot id: G8AUM4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS16935
gene id: 1064539:Sp245p_RS16935
uniprot id: G8AQW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS30455
gene id: 1064539:Sp245p_RS30455
uniprot id: G8AUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1064539:Sp245p RS00485
gene id: 1064539:Sp245p_RS00485
uniprot id: G8AH22
names: Similarity
messages: Belongs to the peptidase C56 family.

1064539:Sp245p RS12870
gene id: 1064539:Sp245p_RS12870
uniprot id: G8AIZ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1064539:Sp245p RS06100
gene id: 1064539:Sp245p_RS06100
uniprot id: G8ANE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1064539:Sp245p RS30260
gene id: 1064539:Sp245p_RS30260
uniprot id: G8AU94
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1064539:Sp245p RS26980
gene id: 1064539:Sp245p_RS26980
uniprot id: G8AUK9
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS33940
gene id: 1064539:Sp245p_RS33940
uniprot id: G8AZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1064539:Sp245p RS20700
gene id: 1064539:Sp245p_RS20700
uniprot id: G8ATD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1064539:Sp245p RS17350
gene id: 1064539:Sp245p_RS17350
uniprot id: G8AR59
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1064539:Sp245p RS10090
gene id: 1064539:Sp245p_RS10090
uniprot id: G8AKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1064539:Sp245p RS11225
gene id: 1064539:Sp245p_RS11225
uniprot id: G8AK28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS01840
gene id: 1064539:Sp245p_RS01840
uniprot id: G8AF97
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS22565
gene id: 1064539:Sp245p_RS22565
uniprot id: G8AY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1064539:Sp245p RS15950
gene id: 1064539:Sp245p_RS15950
uniprot id: G8AQ74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS08780
gene id: 1064539:Sp245p_RS08780
uniprot id: G8ALM2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1064539:Sp245p RS08540
gene id: 1064539:Sp245p_RS08540
uniprot id: G8ALT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS13290
gene id: 1064539:Sp245p_RS13290
uniprot id: G8AIQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1064539:Sp245p RS09380
gene id: 1064539:Sp245p_RS09380
uniprot id: G8AL93
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1064539:Sp245p RS24010
gene id: 1064539:Sp245p_RS24010
uniprot id: G8AX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS32475
gene id: 1064539:Sp245p_RS32475
uniprot id: G8B0N0
names: Similarity
messages: Belongs to the ParB family.

1064539:Sp245p RS09625
gene id: 1064539:Sp245p_RS09625
uniprot id: G8AL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1064539:Sp245p RS31655
gene id: 1064539:Sp245p_RS31655
uniprot id: G8B060
names: Similarity
messages: Belongs to the bacterial secretin family.

1064539:Sp245p RS34295
gene id: 1064539:Sp245p_RS34295
uniprot id: G8AZR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1064539:Sp245p RS09820
gene id: 1064539:Sp245p_RS09820
uniprot id: G8AKZ4
names: Similarity
messages: Belongs to the GST superfamily.

1064539:Sp245p RS13205
gene id: 1064539:Sp245p_RS13205
uniprot id: G8AIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1064539:Sp245p RS06620
gene id: 1064539:Sp245p_RS06620
uniprot id: G8AN29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1064539:Sp245p RS01975
gene id: 1064539:Sp245p_RS01975
uniprot id: G8AF62
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1064539:Sp245p RS01635
gene id: 1064539:Sp245p_RS01635
uniprot id: G8AFE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1064539:Sp245p RS30465
gene id: 1064539:Sp245p_RS30465
uniprot id: G8AUD6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Periplasm

1064539:Sp245p RS25545
gene id: 1064539:Sp245p_RS25545
uniprot id: G8AYK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS05885
gene id: 1064539:Sp245p_RS05885
uniprot id: G8ANJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1064539:Sp245p RS20740
gene id: 1064539:Sp245p_RS20740
uniprot id: G8ATE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1064539:Sp245p RS33060
gene id: 1064539:Sp245p_RS33060
uniprot id: G8AZ00
names: Similarity
messages: Belongs to the TPP enzyme family.

1064539:Sp245p RS21115
gene id: 1064539:Sp245p_RS21115
uniprot id: G8ATM9
names: Similarity
messages: Belongs to the pirin family.

1064539:Sp245p RS00475
gene id: 1064539:Sp245p_RS00475
uniprot id: G8AH26
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1064539:Sp245p RS18415
gene id: 1064539:Sp245p_RS18415
uniprot id: G8ARU8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1064539:Sp245p RS10650
gene id: 1064539:Sp245p_RS10650
uniprot id: G8AKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1064539:Sp245p RS16130
gene id: 1064539:Sp245p_RS16130
uniprot id: G8AQB9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1064539:Sp245p RS30095
gene id: 1064539:Sp245p_RS30095
uniprot id: G8AU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS26615
gene id: 1064539:Sp245p_RS26615
uniprot id: G8B187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1064539:Sp245p RS10185
gene id: 1064539:Sp245p_RS10185
uniprot id: G8AKR8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1064539:Sp245p RS25415
gene id: 1064539:Sp245p_RS25415
uniprot id: G8AYN1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1064539:Sp245p RS30345
gene id: 1064539:Sp245p_RS30345
uniprot id: G8AUB4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1064539:Sp245p RS08000
gene id: 1064539:Sp245p_RS08000
uniprot id: G8AMS6
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.

1064539:Sp245p RS13930
gene id: 1064539:Sp245p_RS13930
uniprot id: G8AI64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1064539:Sp245p RS07895
gene id: 1064539:Sp245p_RS07895
uniprot id: G8AMQ4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1064539:Sp245p RS10030
gene id: 1064539:Sp245p_RS10030
uniprot id: G8AKV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS13640
gene id: 1064539:Sp245p_RS13640
uniprot id: G8AIG9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1064539:Sp245p RS05785
gene id: 1064539:Sp245p_RS05785
uniprot id: G8AEK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1064539:Sp245p RS12205
gene id: 1064539:Sp245p_RS12205
uniprot id: G8AJE7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS17600
gene id: 1064539:Sp245p_RS17600
uniprot id: G8ARB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1064539:Sp245p RS19355
gene id: 1064539:Sp245p_RS19355
uniprot id: G8ASI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS08945
gene id: 1064539:Sp245p_RS08945
uniprot id: G8ALI8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27330
gene id: 1064539:Sp245p_RS27330
uniprot id: G8AUU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS22090
gene id: 1064539:Sp245p_RS22090
uniprot id: G8AP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1064539:Sp245p RS08865
gene id: 1064539:Sp245p_RS08865
uniprot id: G8ALK5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18005
gene id: 1064539:Sp245p_RS18005
uniprot id: G8ARK6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1064539:Sp245p RS17455
gene id: 1064539:Sp245p_RS17455
uniprot id: G8AR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1064539:Sp245p RS10475
gene id: 1064539:Sp245p_RS10475
uniprot id: G8AKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1064539:Sp245p RS07990
gene id: 1064539:Sp245p_RS07990
uniprot id: G8AMS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1064539:Sp245p RS10805
gene id: 1064539:Sp245p_RS10805
uniprot id: G8AKD2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1064539:Sp245p RS24610
gene id: 1064539:Sp245p_RS24610
uniprot id: G8AWU2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS09685
gene id: 1064539:Sp245p_RS09685
uniprot id: G8AL24
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1064539:Sp245p RS06305
gene id: 1064539:Sp245p_RS06305
uniprot id: G8AN99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1064539:Sp245p RS16895
gene id: 1064539:Sp245p_RS16895
uniprot id: G8AQV7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS10825
gene id: 1064539:Sp245p_RS10825
uniprot id: G8AKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1064539:Sp245p RS19295
gene id: 1064539:Sp245p_RS19295
uniprot id: G8ASH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS19075
gene id: 1064539:Sp245p_RS19075
uniprot id: G8ASB6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1064539:Sp245p RS17680
gene id: 1064539:Sp245p_RS17680
uniprot id: G8ARD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1064539:Sp245p RS04270
gene id: 1064539:Sp245p_RS04270
uniprot id: G8AGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1064539:Sp245p RS33955
gene id: 1064539:Sp245p_RS33955
uniprot id: G8AZI4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1064539:Sp245p RS33225
gene id: 1064539:Sp245p_RS33225
uniprot id: G8AZ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1064539:Sp245p RS04535
gene id: 1064539:Sp245p_RS04535
uniprot id: G8AFX0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1064539:Sp245p RS00745
gene id: 1064539:Sp245p_RS00745
uniprot id: G8AGF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1064539:Sp245p RS21630
gene id: 1064539:Sp245p_RS21630
uniprot id: G8ANT7
names: Similarity
messages: Belongs to the HupF/HypC family.

1064539:Sp245p RS14510
gene id: 1064539:Sp245p_RS14510
uniprot id: G8APB3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1064539:Sp245p RS02610
gene id: 1064539:Sp245p_RS02610
uniprot id: G8AEB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1064539:Sp245p RS10690
gene id: 1064539:Sp245p_RS10690
uniprot id: G8AKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1064539:Sp245p RS34190
gene id: 1064539:Sp245p_RS34190
uniprot id: G8AZP0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1064539:Sp245p RS02360
gene id: 1064539:Sp245p_RS02360
uniprot id: G8AEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1064539:Sp245p RS31980
gene id: 1064539:Sp245p_RS31980
uniprot id: G8B0D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS32645
gene id: 1064539:Sp245p_RS32645
uniprot id: G8B0J2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS23825
gene id: 1064539:Sp245p_RS23825
uniprot id: G8AXC3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS07375
gene id: 1064539:Sp245p_RS07375
uniprot id: G8AMD4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1064539:Sp245p RS34365
gene id: 1064539:Sp245p_RS34365
uniprot id: G8AZS7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1064539:Sp245p RS27030
gene id: 1064539:Sp245p_RS27030
uniprot id: G8AUM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1064539:Sp245p RS25050
gene id: 1064539:Sp245p_RS25050
uniprot id: G8AWJ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1064539:Sp245p RS33080
gene id: 1064539:Sp245p_RS33080
uniprot id: G8AZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1064539:Sp245p RS02745
gene id: 1064539:Sp245p_RS02745
uniprot id: G8AE82
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1064539:Sp245p RS25240
gene id: 1064539:Sp245p_RS25240
uniprot id: G8AYR9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1064539:Sp245p RS32130
gene id: 1064539:Sp245p_RS32130
uniprot id: G8B0E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1064539:Sp245p RS26330
gene id: 1064539:Sp245p_RS26330
uniprot id: G8B1E5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1064539:Sp245p RS27935
gene id: 1064539:Sp245p_RS27935
uniprot id: G8AVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS13240
gene id: 1064539:Sp245p_RS13240
uniprot id: G8AIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1064539:Sp245p RS15220
gene id: 1064539:Sp245p_RS15220
uniprot id: G8APR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1064539:Sp245p RS07430
gene id: 1064539:Sp245p_RS07430
uniprot id: G8AME6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS11665
gene id: 1064539:Sp245p_RS11665
uniprot id: G8AJS4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1064539:Sp245p RS02910
gene id: 1064539:Sp245p_RS02910
uniprot id: G8AIF6
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS04775
gene id: 1064539:Sp245p_RS04775
uniprot id: G8AFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1064539:Sp245p RS19595
gene id: 1064539:Sp245p_RS19595
uniprot id: G8ASP0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS12805
gene id: 1064539:Sp245p_RS12805
uniprot id: G8AJ13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1064539:Sp245p RS13535
gene id: 1064539:Sp245p_RS13535
uniprot id: G8AIJ5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS02165
gene id: 1064539:Sp245p_RS02165
uniprot id: G8AF20
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1064539:Sp245p RS17405
gene id: 1064539:Sp245p_RS17405
uniprot id: G8AR74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1064539:Sp245p RS16165
gene id: 1064539:Sp245p_RS16165
uniprot id: G8AQD0
names: Similarity
messages: Belongs to the peptidase M1 family.

1064539:Sp245p RS15965
gene id: 1064539:Sp245p_RS15965
uniprot id: G8AQ77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS18220
gene id: 1064539:Sp245p_RS18220
uniprot id: G8ARQ4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1064539:Sp245p RS21250
gene id: 1064539:Sp245p_RS21250
uniprot id: G8ATR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1064539:Sp245p RS01875
gene id: 1064539:Sp245p_RS01875
uniprot id: G8AF88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1064539:Sp245p RS16055
gene id: 1064539:Sp245p_RS16055
uniprot id: G8AQ99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS16905
gene id: 1064539:Sp245p_RS16905
uniprot id: G8AQV9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS31430
gene id: 1064539:Sp245p_RS31430
uniprot id: G8B009
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS22135
gene id: 1064539:Sp245p_RS22135
uniprot id: G8AP45
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1064539:Sp245p RS01215
gene id: 1064539:Sp245p_RS01215
uniprot id: G8AG48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1064539:Sp245p RS09235
gene id: 1064539:Sp245p_RS09235
uniprot id: G8ALB8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09870
gene id: 1064539:Sp245p_RS09870
uniprot id: G8AKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1064539:Sp245p RS25760
gene id: 1064539:Sp245p_RS25760
uniprot id: G8AYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1064539:Sp245p RS22030
gene id: 1064539:Sp245p_RS22030
uniprot id: G8AP19
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1064539:Sp245p RS06805
gene id: 1064539:Sp245p_RS06805
uniprot id: G8AMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS15625
gene id: 1064539:Sp245p_RS15625
uniprot id: G8AQ01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS18735
gene id: 1064539:Sp245p_RS18735
uniprot id: G8AS23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS10315
gene id: 1064539:Sp245p_RS10315
uniprot id: G8AKP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS30500
gene id: 1064539:Sp245p_RS30500
uniprot id: G8AUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1064539:Sp245p RS04925
gene id: 1064539:Sp245p_RS04925
uniprot id: G8AFL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1064539:Sp245p RS34425
gene id: 1064539:Sp245p_RS34425
uniprot id: G8AZU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS34640
gene id: 1064539:Sp245p_RS34640
uniprot id: G8AZY3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1064539:Sp245p RS33585
gene id: 1064539:Sp245p_RS33585
uniprot id: G8AZA2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1064539:Sp245p RS26295
gene id: 1064539:Sp245p_RS26295
uniprot id: G8B1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1064539:Sp245p RS00615
gene id: 1064539:Sp245p_RS00615
uniprot id: G8AGZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06025
gene id: 1064539:Sp245p_RS06025
uniprot id: G8ANG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1064539:Sp245p RS21225
gene id: 1064539:Sp245p_RS21225
uniprot id: G8ATQ5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1064539:Sp245p RS04145
gene id: 1064539:Sp245p_RS04145
uniprot id: G8AGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS20910
gene id: 1064539:Sp245p_RS20910
uniprot id: G8ATI4
names: Similarity
messages: Belongs to the AHA1 family.

1064539:Sp245p RS21615
gene id: 1064539:Sp245p_RS21615
uniprot id: G8ANT4
names: Similarity
messages: Belongs to the peptidase S41A family.

1064539:Sp245p RS12250
gene id: 1064539:Sp245p_RS12250
uniprot id: G8AJD7
names: Similarity
messages: Belongs to the UPF0261 family.

1064539:Sp245p RS24675
gene id: 1064539:Sp245p_RS24675
uniprot id: G8AWS8
names: Similarity
messages: Belongs to the DSD1 family.

1064539:Sp245p RS10780
gene id: 1064539:Sp245p_RS10780
uniprot id: G8AKD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1064539:Sp245p RS32885
gene id: 1064539:Sp245p_RS32885
uniprot id: G8AYW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1064539:Sp245p RS30835
gene id: 1064539:Sp245p_RS30835
uniprot id: G8B112
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1064539:Sp245p RS29555
gene id: 1064539:Sp245p_RS29555
uniprot id: G8AWE2
names: Similarity
messages: Belongs to the ros/MucR family.

1064539:Sp245p RS13740
gene id: 1064539:Sp245p_RS13740
uniprot id: G8AIA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1064539:Sp245p RS11900
gene id: 1064539:Sp245p_RS11900
uniprot id: G8AJM1
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1064539:Sp245p RS20045
gene id: 1064539:Sp245p_RS20045
uniprot id: G8ASY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1064539:Sp245p RS14100
gene id: 1064539:Sp245p_RS14100
uniprot id: G8AI22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1064539:Sp245p RS01880
gene id: 1064539:Sp245p_RS01880
uniprot id: G8AF87
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1064539:Sp245p RS34205
gene id: 1064539:Sp245p_RS34205
uniprot id: G8AZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS20065
gene id: 1064539:Sp245p_RS20065
uniprot id: G8ASZ2
names: Similarity
messages: Belongs to the LuxC family.

1064539:Sp245p RS14240
gene id: 1064539:Sp245p_RS14240
uniprot id: G8AHZ0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1064539:Sp245p RS25770
gene id: 1064539:Sp245p_RS25770
uniprot id: G8AYF7
names: Similarity
messages: Belongs to the UPF0335 family.

1064539:Sp245p RS12895
gene id: 1064539:Sp245p_RS12895
uniprot id: G8AIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1064539:Sp245p RS12190
gene id: 1064539:Sp245p_RS12190
uniprot id: G8AJF4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1064539:Sp245p RS08830
gene id: 1064539:Sp245p_RS08830
uniprot id: G8ALL2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1064539:Sp245p RS15690
gene id: 1064539:Sp245p_RS15690
uniprot id: G8AQ15
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1064539:Sp245p RS27135
gene id: 1064539:Sp245p_RS27135
uniprot id: G8AUP6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS08855
gene id: 1064539:Sp245p_RS08855
uniprot id: G8ALK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1064539:Sp245p RS18410
gene id: 1064539:Sp245p_RS18410
uniprot id: G8ARU7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS26340
gene id: 1064539:Sp245p_RS26340
uniprot id: G8B1E3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1064539:Sp245p RS33040
gene id: 1064539:Sp245p_RS33040
uniprot id: G8AYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1064539:Sp245p RS21085
gene id: 1064539:Sp245p_RS21085
uniprot id: G8ATM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS23040
gene id: 1064539:Sp245p_RS23040
uniprot id: G8AXV7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1064539:Sp245p RS18145
gene id: 1064539:Sp245p_RS18145
uniprot id: G8ARN5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS00700
gene id: 1064539:Sp245p_RS00700
uniprot id: G8AGG0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1064539:Sp245p RS11995
gene id: 1064539:Sp245p_RS11995
uniprot id: G8AJK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1064539:Sp245p RS01915
gene id: 1064539:Sp245p_RS01915
uniprot id: G8AF79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1064539:Sp245p RS14320
gene id: 1064539:Sp245p_RS14320
uniprot id: G8AHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1064539:Sp245p RS13505
gene id: 1064539:Sp245p_RS13505
uniprot id: G8AIK2
names: Similarity
messages: Belongs to the GST superfamily.

1064539:Sp245p RS33035
gene id: 1064539:Sp245p_RS33035
uniprot id: G8AYZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1064539:Sp245p RS02545
gene id: 1064539:Sp245p_RS02545
uniprot id: G8AEC6
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1064539:Sp245p RS02275
gene id: 1064539:Sp245p_RS02275
uniprot id: G8AEI6
names: Similarity
messages: Belongs to the NadC/ModD family.

1064539:Sp245p RS12145
gene id: 1064539:Sp245p_RS12145
uniprot id: G8AJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1064539:Sp245p RS15295
gene id: 1064539:Sp245p_RS15295
uniprot id: G8APS7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS20830
gene id: 1064539:Sp245p_RS20830
uniprot id: G8ATG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1064539:Sp245p RS22985
gene id: 1064539:Sp245p_RS22985
uniprot id: G8AXX0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18945
gene id: 1064539:Sp245p_RS18945
uniprot id: G8AS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1064539:Sp245p RS23775
gene id: 1064539:Sp245p_RS23775
uniprot id: G8AXD4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS21955
gene id: 1064539:Sp245p_RS21955
uniprot id: G8AP03
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1064539:Sp245p RS00715
gene id: 1064539:Sp245p_RS00715
uniprot id: G8AGF7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1064539:Sp245p RS08165
gene id: 1064539:Sp245p_RS08165
uniprot id: G8AMW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1064539:Sp245p RS04920
gene id: 1064539:Sp245p_RS04920
uniprot id: G8AFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1064539:Sp245p RS01230
gene id: 1064539:Sp245p_RS01230
uniprot id: G8AG45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1064539:Sp245p RS29085
gene id: 1064539:Sp245p_RS29085
uniprot id: G8AW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS07550
gene id: 1064539:Sp245p_RS07550
uniprot id: G8AMH4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1064539:Sp245p RS11170
gene id: 1064539:Sp245p_RS11170
uniprot id: G8AK41
names: Similarity
messages: Belongs to the UPF0047 family.

1064539:Sp245p RS31465
gene id: 1064539:Sp245p_RS31465
uniprot id: G8B015
names: Similarity
messages: Belongs to the PrpD family.

1064539:Sp245p RS03100
gene id: 1064539:Sp245p_RS03100
uniprot id: G8AHV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS13825
gene id: 1064539:Sp245p_RS13825
uniprot id: G8AI87
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS01340
gene id: 1064539:Sp245p_RS01340
uniprot id: G8AG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS04315
gene id: 1064539:Sp245p_RS04315
uniprot id: G8AGJ3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS02190
gene id: 1064539:Sp245p_RS02190
uniprot id: G8AF15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1064539:Sp245p RS16850
gene id: 1064539:Sp245p_RS16850
uniprot id: G8AQU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS05725
gene id: 1064539:Sp245p_RS05725
uniprot id: G8AEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1064539:Sp245p RS02320
gene id: 1064539:Sp245p_RS02320
uniprot id: G8AEH8
names: Similarity
messages: Belongs to the thioredoxin family.

1064539:Sp245p RS17235
gene id: 1064539:Sp245p_RS17235
uniprot id: G8AR29
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1064539:Sp245p RS10750
gene id: 1064539:Sp245p_RS10750
uniprot id: G8AKE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1064539:Sp245p RS33590
gene id: 1064539:Sp245p_RS33590
uniprot id: G8AZA3
names: Similarity
messages: Belongs to the arginase family.

1064539:Sp245p RS01015
gene id: 1064539:Sp245p_RS01015
uniprot id: G8AG93
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1064539:Sp245p RS01590
gene id: 1064539:Sp245p_RS01590
uniprot id: G8AFF2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS23185
gene id: 1064539:Sp245p_RS23185
uniprot id: G8AXS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS27495
gene id: 1064539:Sp245p_RS27495
uniprot id: G8AUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1064539:Sp245p RS13210
gene id: 1064539:Sp245p_RS13210
uniprot id: G8AIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1064539:Sp245p RS10920
gene id: 1064539:Sp245p_RS10920
uniprot id: G8AKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1064539:Sp245p RS27780
gene id: 1064539:Sp245p_RS27780
uniprot id: G8AV62
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1064539:Sp245p RS01160
gene id: 1064539:Sp245p_RS01160
uniprot id: G8AG60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS32715
gene id: 1064539:Sp245p_RS32715
uniprot id: G8B0I0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS20220
gene id: 1064539:Sp245p_RS20220
uniprot id: G8AT29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1064539:Sp245p RS09305
gene id: 1064539:Sp245p_RS09305
uniprot id: G8ALB0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1064539:Sp245p RS13635
gene id: 1064539:Sp245p_RS13635
uniprot id: G8AIH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1064539:Sp245p RS06885
gene id: 1064539:Sp245p_RS06885
uniprot id: G8AM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1064539:Sp245p RS30140
gene id: 1064539:Sp245p_RS30140
uniprot id: G8AU67
names: Function
names: Similarity
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

1064539:Sp245p RS06870
gene id: 1064539:Sp245p_RS06870
uniprot id: G8AM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1064539:Sp245p RS16825
gene id: 1064539:Sp245p_RS16825
uniprot id: G8AQU2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1064539:Sp245p RS01445
gene id: 1064539:Sp245p_RS01445
uniprot id: G8AFZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS02255
gene id: 1064539:Sp245p_RS02255
uniprot id: G8AEJ0
names: Similarity
messages: Belongs to the YggT family.

1064539:Sp245p RS26305
gene id: 1064539:Sp245p_RS26305
uniprot id: G8B1F0
names: Subcellular Location Annotation
messages: Secreted

1064539:Sp245p RS29390
gene id: 1064539:Sp245p_RS29390
uniprot id: G8AWA0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS00565
gene id: 1064539:Sp245p_RS00565
uniprot id: G8AH03
names: Similarity
messages: Belongs to the creatininase superfamily.

1064539:Sp245p RS19825
gene id: 1064539:Sp245p_RS19825
uniprot id: G8AST3
names: Similarity
messages: Belongs to the ParB family.

1064539:Sp245p RS26555
gene id: 1064539:Sp245p_RS26555
uniprot id: G8B199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1064539:Sp245p RS21525
gene id: 1064539:Sp245p_RS21525
uniprot id: G8ANR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS05285
gene id: 1064539:Sp245p_RS05285
uniprot id: G8AEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1064539:Sp245p RS14635
gene id: 1064539:Sp245p_RS14635
uniprot id: G8APD8
names: Similarity
messages: Belongs to the VgrG protein family.

1064539:Sp245p RS33315
gene id: 1064539:Sp245p_RS33315
uniprot id: G8AZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

1064539:Sp245p RS10300
gene id: 1064539:Sp245p_RS10300
uniprot id: G8AKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1064539:Sp245p RS20965
gene id: 1064539:Sp245p_RS20965
uniprot id: G8ATJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS15190
gene id: 1064539:Sp245p_RS15190
uniprot id: G8APQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS22390
gene id: 1064539:Sp245p_RS22390
uniprot id: G8AYA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1064539:Sp245p RS06710
gene id: 1064539:Sp245p_RS06710
uniprot id: G8AN10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1064539:Sp245p RS27585
gene id: 1064539:Sp245p_RS27585
uniprot id: G8AV00
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS10595
gene id: 1064539:Sp245p_RS10595
uniprot id: G8AKH8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS01865
gene id: 1064539:Sp245p_RS01865
uniprot id: G8AF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS17090
gene id: 1064539:Sp245p_RS17090
uniprot id: G8AQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS27000
gene id: 1064539:Sp245p_RS27000
uniprot id: G8AUL5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1064539:Sp245p RS03880
gene id: 1064539:Sp245p_RS03880
uniprot id: G8AGU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS06995
gene id: 1064539:Sp245p_RS06995
uniprot id: G8AM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS00695
gene id: 1064539:Sp245p_RS00695
uniprot id: G8AGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS32990
gene id: 1064539:Sp245p_RS32990
uniprot id: G8AYY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS00470
gene id: 1064539:Sp245p_RS00470
uniprot id: G8AH28
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1064539:Sp245p RS07440
gene id: 1064539:Sp245p_RS07440
uniprot id: G8AME8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS09300
gene id: 1064539:Sp245p_RS09300
uniprot id: G8ALB1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1064539:Sp245p RS06475
gene id: 1064539:Sp245p_RS06475
uniprot id: G8AN60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1064539:Sp245p RS10095
gene id: 1064539:Sp245p_RS10095
uniprot id: G8AKT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1064539:Sp245p RS05555
gene id: 1064539:Sp245p_RS05555
uniprot id: G8AEQ8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27440
gene id: 1064539:Sp245p_RS27440
uniprot id: G8AUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS10060
gene id: 1064539:Sp245p_RS10060
uniprot id: G8AKU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS05055
gene id: 1064539:Sp245p_RS05055
uniprot id: G8AFI6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23065
gene id: 1064539:Sp245p_RS23065
uniprot id: G8AXV2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1064539:Sp245p RS02270
gene id: 1064539:Sp245p_RS02270
uniprot id: G8AEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1064539:Sp245p RS30475
gene id: 1064539:Sp245p_RS30475
uniprot id: G8AUD8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1064539:Sp245p RS32910
gene id: 1064539:Sp245p_RS32910
uniprot id: G8AYW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1064539:Sp245p RS10320
gene id: 1064539:Sp245p_RS10320
uniprot id: G8AKN9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1064539:Sp245p RS18950
gene id: 1064539:Sp245p_RS18950
uniprot id: G8AS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1064539:Sp245p RS20630
gene id: 1064539:Sp245p_RS20630
uniprot id: G8ATC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS31100
gene id: 1064539:Sp245p_RS31100
uniprot id: G8B0R9
names: Similarity
messages: Belongs to the peptidase S1B family.

1064539:Sp245p RS23340
gene id: 1064539:Sp245p_RS23340
uniprot id: G8AXN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1064539:Sp245p RS22850
gene id: 1064539:Sp245p_RS22850
uniprot id: G8AXZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1064539:Sp245p RS16710
gene id: 1064539:Sp245p_RS16710
uniprot id: G8AQR4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1064539:Sp245p RS12120
gene id: 1064539:Sp245p_RS12120
uniprot id: G8AJH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS34395
gene id: 1064539:Sp245p_RS34395
uniprot id: G8AZT4
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS22100
gene id: 1064539:Sp245p_RS22100
uniprot id: G8AP34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1064539:Sp245p RS16985
gene id: 1064539:Sp245p_RS16985
uniprot id: G8AQX5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1064539:Sp245p RS21310
gene id: 1064539:Sp245p_RS21310
uniprot id: G8ATS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS19395
gene id: 1064539:Sp245p_RS19395
uniprot id: G8ASJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1064539:Sp245p RS20470
gene id: 1064539:Sp245p_RS20470
uniprot id: G8AT83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS16040
gene id: 1064539:Sp245p_RS16040
uniprot id: G8AQ93
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1064539:Sp245p RS00370
gene id: 1064539:Sp245p_RS00370
uniprot id: G8AH54
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS21810
gene id: 1064539:Sp245p_RS21810
uniprot id: G8ANX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05705
gene id: 1064539:Sp245p_RS05705
uniprot id: G8AEM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1064539:Sp245p RS13390
gene id: 1064539:Sp245p_RS13390
uniprot id: G8AIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS24475
gene id: 1064539:Sp245p_RS24475
uniprot id: G8AWX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS19270
gene id: 1064539:Sp245p_RS19270
uniprot id: G8ASG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS02980
gene id: 1064539:Sp245p_RS02980
uniprot id: G8AIE2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1064539:Sp245p RS07865
gene id: 1064539:Sp245p_RS07865
uniprot id: G8AMP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1064539:Sp245p RS08610
gene id: 1064539:Sp245p_RS08610
uniprot id: G8ALR7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1064539:Sp245p RS09150
gene id: 1064539:Sp245p_RS09150
uniprot id: G8ALD9
names: Similarity
messages: Belongs to the peptidase C56 family.

1064539:Sp245p RS22885
gene id: 1064539:Sp245p_RS22885
uniprot id: G8AXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS20970
gene id: 1064539:Sp245p_RS20970
uniprot id: G8ATJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS20340
gene id: 1064539:Sp245p_RS20340
uniprot id: G8AT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1064539:Sp245p RS05190
gene id: 1064539:Sp245p_RS05190
uniprot id: G8AEY7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1064539:Sp245p RS02400
gene id: 1064539:Sp245p_RS02400
uniprot id: G8AEF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1064539:Sp245p RS26935
gene id: 1064539:Sp245p_RS26935
uniprot id: G8AUJ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS02445
gene id: 1064539:Sp245p_RS02445
uniprot id: G8AEE9
names: Subunit
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1064539:Sp245p RS08290
gene id: 1064539:Sp245p_RS08290
uniprot id: G8ALY6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1064539:Sp245p RS06575
gene id: 1064539:Sp245p_RS06575
uniprot id: G8AN39
names: Similarity
messages: Belongs to the virb1 family.

1064539:Sp245p RS04710
gene id: 1064539:Sp245p_RS04710
uniprot id: G8AFR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1064539:Sp245p RS16300
gene id: 1064539:Sp245p_RS16300
uniprot id: G8AQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1064539:Sp245p RS05280
gene id: 1064539:Sp245p_RS05280
uniprot id: G8AEW9
names: Similarity
messages: Belongs to the peptidase U62 family.

1064539:Sp245p RS09655
gene id: 1064539:Sp245p_RS09655
uniprot id: G8AL31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS05765
gene id: 1064539:Sp245p_RS05765
uniprot id: G8AEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1064539:Sp245p RS09975
gene id: 1064539:Sp245p_RS09975
uniprot id: G8AKW2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1064539:Sp245p RS05815
gene id: 1064539:Sp245p_RS05815
uniprot id: G8ANL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1064539:Sp245p RS09070
gene id: 1064539:Sp245p_RS09070
uniprot id: G8ALF7
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS24405
gene id: 1064539:Sp245p_RS24405
uniprot id: G8AWY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1064539:Sp245p RS12170
gene id: 1064539:Sp245p_RS12170
uniprot id: G8AJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1064539:Sp245p RS21540
gene id: 1064539:Sp245p_RS21540
uniprot id: G8ANR6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

1064539:Sp245p RS10260
gene id: 1064539:Sp245p_RS10260
uniprot id: G8AKQ3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1064539:Sp245p RS10265
gene id: 1064539:Sp245p_RS10265
uniprot id: G8AKQ2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS30330
gene id: 1064539:Sp245p_RS30330
uniprot id: G8AUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS27150
gene id: 1064539:Sp245p_RS27150
uniprot id: G8AUP9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09430
gene id: 1064539:Sp245p_RS09430
uniprot id: G8AL82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1064539:Sp245p RS20780
gene id: 1064539:Sp245p_RS20780
uniprot id: G8ATF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1064539:Sp245p RS18045
gene id: 1064539:Sp245p_RS18045
uniprot id: G8ARL5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1064539:Sp245p RS29610
gene id: 1064539:Sp245p_RS29610
uniprot id: G8ATT4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS27855
gene id: 1064539:Sp245p_RS27855
uniprot id: G8AV84
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1064539:Sp245p RS05685
gene id: 1064539:Sp245p_RS05685
uniprot id: G8AEM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1064539:Sp245p RS24735
gene id: 1064539:Sp245p_RS24735
uniprot id: G8AWR6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1064539:Sp245p RS13365
gene id: 1064539:Sp245p_RS13365
uniprot id: G8AIN7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1064539:Sp245p RS02690
gene id: 1064539:Sp245p_RS02690
uniprot id: G8AE97
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1064539:Sp245p RS01545
gene id: 1064539:Sp245p_RS01545
uniprot id: G8AFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS14350
gene id: 1064539:Sp245p_RS14350
uniprot id: G8AHW6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1064539:Sp245p RS34145
gene id: 1064539:Sp245p_RS34145
uniprot id: G8AZN0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1064539:Sp245p RS11865
gene id: 1064539:Sp245p_RS11865
uniprot id: G8AJN1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1064539:Sp245p RS07710
gene id: 1064539:Sp245p_RS07710
uniprot id: G8AML1
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS05835
gene id: 1064539:Sp245p_RS05835
uniprot id: G8ANK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1064539:Sp245p RS10800
gene id: 1064539:Sp245p_RS10800
uniprot id: G8AKD3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1064539:Sp245p RS31845
gene id: 1064539:Sp245p_RS31845
uniprot id: G8B099
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS06455
gene id: 1064539:Sp245p_RS06455
uniprot id: G8AN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1064539:Sp245p RS23345
gene id: 1064539:Sp245p_RS23345
uniprot id: G8AXN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1064539:Sp245p RS19715
gene id: 1064539:Sp245p_RS19715
uniprot id: G8ASR6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1064539:Sp245p RS14340
gene id: 1064539:Sp245p_RS14340
uniprot id: G8AHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1064539:Sp245p RS13625
gene id: 1064539:Sp245p_RS13625
uniprot id: G8AIH2
names: Subcellular Location Annotation
messages: Cytoplasm

1064539:Sp245p RS08390
gene id: 1064539:Sp245p_RS08390
uniprot id: G8ALW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS12880
gene id: 1064539:Sp245p_RS12880
uniprot id: G8AIZ5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1064539:Sp245p RS00330
gene id: 1064539:Sp245p_RS00330
uniprot id: G8AH63
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS17540
gene id: 1064539:Sp245p_RS17540
uniprot id: G8ARA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS33235
gene id: 1064539:Sp245p_RS33235
uniprot id: G8AZ44
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1064539:Sp245p RS17435
gene id: 1064539:Sp245p_RS17435
uniprot id: G8AR80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS07870
gene id: 1064539:Sp245p_RS07870
uniprot id: G8AMP9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1064539:Sp245p RS05935
gene id: 1064539:Sp245p_RS05935
uniprot id: G8ANI3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1064539:Sp245p RS28705
gene id: 1064539:Sp245p_RS28705
uniprot id: G8AVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS31475
gene id: 1064539:Sp245p_RS31475
uniprot id: G8B017
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1064539:Sp245p RS15635
gene id: 1064539:Sp245p_RS15635
uniprot id: G8AQ03
names: Similarity
messages: Belongs to the DEAD box helicase family.

1064539:Sp245p RS10470
gene id: 1064539:Sp245p_RS10470
uniprot id: G8AKK6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS08730
gene id: 1064539:Sp245p_RS08730
uniprot id: G8ALN4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1064539:Sp245p RS20355
gene id: 1064539:Sp245p_RS20355
uniprot id: G8AT59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1064539:Sp245p RS07610
gene id: 1064539:Sp245p_RS07610
uniprot id: G8AMI6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS12135
gene id: 1064539:Sp245p_RS12135
uniprot id: G8AJG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS13335
gene id: 1064539:Sp245p_RS13335
uniprot id: G8AIP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1064539:Sp245p RS10630
gene id: 1064539:Sp245p_RS10630
uniprot id: G8AKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1064539:Sp245p RS29985
gene id: 1064539:Sp245p_RS29985
uniprot id: G8AU28
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS15820
gene id: 1064539:Sp245p_RS15820
uniprot id: G8AQ44
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09775
gene id: 1064539:Sp245p_RS09775
uniprot id: G8AL05
names: Similarity
messages: Belongs to the TrpC family.

1064539:Sp245p RS14455
gene id: 1064539:Sp245p_RS14455
uniprot id: G8APA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS29150
gene id: 1064539:Sp245p_RS29150
uniprot id: G8AW38
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS34315
gene id: 1064539:Sp245p_RS34315
uniprot id: G8AZR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1064539:Sp245p RS29300
gene id: 1064539:Sp245p_RS29300
uniprot id: G8AW73
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS09090
gene id: 1064539:Sp245p_RS09090
uniprot id: G8ALF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1064539:Sp245p RS10040
gene id: 1064539:Sp245p_RS10040
uniprot id: G8AKU9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1064539:Sp245p RS02825
gene id: 1064539:Sp245p_RS02825
uniprot id: G8AE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS10635
gene id: 1064539:Sp245p_RS10635
uniprot id: G8AKG9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1064539:Sp245p RS13465
gene id: 1064539:Sp245p_RS13465
uniprot id: G8AIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1064539:Sp245p RS33100
gene id: 1064539:Sp245p_RS33100
uniprot id: G8AZ08
names: Similarity
messages: Belongs to the UPF0111 family.

1064539:Sp245p RS10870
gene id: 1064539:Sp245p_RS10870
uniprot id: G8AKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1064539:Sp245p RS00725
gene id: 1064539:Sp245p_RS00725
uniprot id: G8AGF5
names: Similarity
messages: Belongs to the UPF0102 family.

1064539:Sp245p RS24965
gene id: 1064539:Sp245p_RS24965
uniprot id: G8AWK5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS34350
gene id: 1064539:Sp245p_RS34350
uniprot id: G8AZS4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS11440
gene id: 1064539:Sp245p_RS11440
uniprot id: G8AJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1064539:Sp245p RS11950
gene id: 1064539:Sp245p_RS11950
uniprot id: G8AJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1064539:Sp245p RS32410
gene id: 1064539:Sp245p_RS32410
uniprot id: G8B0P7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS15325
gene id: 1064539:Sp245p_RS15325
uniprot id: G8APT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1064539:Sp245p RS11460
gene id: 1064539:Sp245p_RS11460
uniprot id: G8AJX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS04155
gene id: 1064539:Sp245p_RS04155
uniprot id: G8AGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS10370
gene id: 1064539:Sp245p_RS10370
uniprot id: G8AKM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1064539:Sp245p RS31195
gene id: 1064539:Sp245p_RS31195
uniprot id: G8B0T9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS19470
gene id: 1064539:Sp245p_RS19470
uniprot id: G8ASL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS05060
gene id: 1064539:Sp245p_RS05060
uniprot id: G8AFI5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS21425
gene id: 1064539:Sp245p_RS21425
uniprot id: G8ANN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06990
gene id: 1064539:Sp245p_RS06990
uniprot id: G8AM42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS13190
gene id: 1064539:Sp245p_RS13190
uniprot id: G8AIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1064539:Sp245p RS02215
gene id: 1064539:Sp245p_RS02215
uniprot id: G8AEJ8
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1064539:Sp245p RS01200
gene id: 1064539:Sp245p_RS01200
uniprot id: G8AG51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1064539:Sp245p RS35885
gene id: 1064539:Sp245p_RS35885
uniprot id: G8AXH2
names: Similarity
messages: Belongs to the transposase 7 family.

1064539:Sp245p RS17805
gene id: 1064539:Sp245p_RS17805
uniprot id: G8ARG1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1064539:Sp245p RS32155
gene id: 1064539:Sp245p_RS32155
uniprot id: G8B0F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1064539:Sp245p RS29095
gene id: 1064539:Sp245p_RS29095
uniprot id: G8AW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS34655
gene id: 1064539:Sp245p_RS34655
uniprot id: G8AZY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS02110
gene id: 1064539:Sp245p_RS02110
uniprot id: G8AF30
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1064539:Sp245p RS18260
gene id: 1064539:Sp245p_RS18260
uniprot id: G8ARR2
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS31975
gene id: 1064539:Sp245p_RS31975
uniprot id: G8B0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1064539:Sp245p RS34380
gene id: 1064539:Sp245p_RS34380
uniprot id: G8AZT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1064539:Sp245p RS24855
gene id: 1064539:Sp245p_RS24855
uniprot id: G8AWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS30210
gene id: 1064539:Sp245p_RS30210
uniprot id: G8AU81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS28335
gene id: 1064539:Sp245p_RS28335
uniprot id: G8AVJ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1064539:Sp245p RS23555
gene id: 1064539:Sp245p_RS23555
uniprot id: G8AXJ3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1064539:Sp245p RS01110
gene id: 1064539:Sp245p_RS01110
uniprot id: G8AG72
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1064539:Sp245p RS24005
gene id: 1064539:Sp245p_RS24005
uniprot id: G8AX79
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS00390
gene id: 1064539:Sp245p_RS00390
uniprot id: G8AH50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1064539:Sp245p RS17215
gene id: 1064539:Sp245p_RS17215
uniprot id: G8AR24
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS33335
gene id: 1064539:Sp245p_RS33335
uniprot id: G8AMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1064539:Sp245p RS14640
gene id: 1064539:Sp245p_RS14640
uniprot id: G8APD9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1064539:Sp245p RS07515
gene id: 1064539:Sp245p_RS07515
uniprot id: G8AMG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1064539:Sp245p RS32855
gene id: 1064539:Sp245p_RS32855
uniprot id: G8AYV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS11140
gene id: 1064539:Sp245p_RS11140
uniprot id: G8AK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1064539:Sp245p RS05820
gene id: 1064539:Sp245p_RS05820
uniprot id: G8ANK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1064539:Sp245p RS18175
gene id: 1064539:Sp245p_RS18175
uniprot id: G8ARP3
names: Similarity
messages: Belongs to the Nth/MutY family.

1064539:Sp245p RS12085
gene id: 1064539:Sp245p_RS12085
uniprot id: G8AJI1
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS11655
gene id: 1064539:Sp245p_RS11655
uniprot id: G8AJS6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1064539:Sp245p RS23570
gene id: 1064539:Sp245p_RS23570
uniprot id: G8AXI5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS22300
gene id: 1064539:Sp245p_RS22300
uniprot id: G8AP92
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27455
gene id: 1064539:Sp245p_RS27455
uniprot id: G8AUX0
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS11615
gene id: 1064539:Sp245p_RS11615
uniprot id: G8AJT6
names: Similarity
messages: Belongs to the ArsC family.

1064539:Sp245p RS01580
gene id: 1064539:Sp245p_RS01580
uniprot id: G8AFF4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS08355
gene id: 1064539:Sp245p_RS08355
uniprot id: G8ALX2
names: Similarity
messages: Belongs to the agmatine deiminase family.

1064539:Sp245p RS13895
gene id: 1064539:Sp245p_RS13895
uniprot id: G8AI71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1064539:Sp245p RS27300
gene id: 1064539:Sp245p_RS27300
uniprot id: G8AUT3
names: Similarity
messages: Belongs to the thioredoxin family.

1064539:Sp245p RS09640
gene id: 1064539:Sp245p_RS09640
uniprot id: G8AL35
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1064539:Sp245p RS05205
gene id: 1064539:Sp245p_RS05205
uniprot id: G8AEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1064539:Sp245p RS27185
gene id: 1064539:Sp245p_RS27185
uniprot id: G8AUQ8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1064539:Sp245p RS02850
gene id: 1064539:Sp245p_RS02850
uniprot id: G8AE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS14075
gene id: 1064539:Sp245p_RS14075
uniprot id: G8AI28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1064539:Sp245p RS31210
gene id: 1064539:Sp245p_RS31210
uniprot id: G8B0U2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1064539:Sp245p RS12320
gene id: 1064539:Sp245p_RS12320
uniprot id: G8AJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS14825
gene id: 1064539:Sp245p_RS14825
uniprot id: G8APH7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1064539:Sp245p RS13685
gene id: 1064539:Sp245p_RS13685
uniprot id: G8AIB9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1064539:Sp245p RS18280
gene id: 1064539:Sp245p_RS18280
uniprot id: G8ARR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1064539:Sp245p RS21290
gene id: 1064539:Sp245p_RS21290
uniprot id: G8ATS0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1064539:Sp245p RS01470
gene id: 1064539:Sp245p_RS01470
uniprot id: G8AFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1064539:Sp245p RS26500
gene id: 1064539:Sp245p_RS26500
uniprot id: G8B1B0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1064539:Sp245p RS02755
gene id: 1064539:Sp245p_RS02755
uniprot id: G8AE80
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1064539:Sp245p RS28930
gene id: 1064539:Sp245p_RS28930
uniprot id: G8AVY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS20885
gene id: 1064539:Sp245p_RS20885
uniprot id: G8ATH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1064539:Sp245p RS21445
gene id: 1064539:Sp245p_RS21445
uniprot id: G8ANP2
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1064539:Sp245p RS06245
gene id: 1064539:Sp245p_RS06245
uniprot id: G8ANB5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1064539:Sp245p RS05720
gene id: 1064539:Sp245p_RS05720
uniprot id: G8AEM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1064539:Sp245p RS01775
gene id: 1064539:Sp245p_RS01775
uniprot id: G8AFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1064539:Sp245p RS07250
gene id: 1064539:Sp245p_RS07250
uniprot id: G8AMA6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS06860
gene id: 1064539:Sp245p_RS06860
uniprot id: G8AM14
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1064539:Sp245p RS25180
gene id: 1064539:Sp245p_RS25180
uniprot id: G8AWF9
names: Similarity
messages: Belongs to the ParB family.

1064539:Sp245p RS26590
gene id: 1064539:Sp245p_RS26590
uniprot id: G8B192
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS20760
gene id: 1064539:Sp245p_RS20760
uniprot id: G8ATF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1064539:Sp245p RS22470
gene id: 1064539:Sp245p_RS22470
uniprot id: G8AY85
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS24940
gene id: 1064539:Sp245p_RS24940
uniprot id: G8AWL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1064539:Sp245p RS10025
gene id: 1064539:Sp245p_RS10025
uniprot id: G8AKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1064539:Sp245p RS22115
gene id: 1064539:Sp245p_RS22115
uniprot id: G8AP37
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1064539:Sp245p RS03220
gene id: 1064539:Sp245p_RS03220
uniprot id: G8AHS1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS07290
gene id: 1064539:Sp245p_RS07290
uniprot id: G8AMB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1064539:Sp245p RS11715
gene id: 1064539:Sp245p_RS11715
uniprot id: G8AJR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1064539:Sp245p RS14285
gene id: 1064539:Sp245p_RS14285
uniprot id: G8AHY0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1064539:Sp245p RS05675
gene id: 1064539:Sp245p_RS05675
uniprot id: G8AEN0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1064539:Sp245p RS14595
gene id: 1064539:Sp245p_RS14595
uniprot id: G8APD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS20180
gene id: 1064539:Sp245p_RS20180
uniprot id: G8AT20
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1064539:Sp245p RS05320
gene id: 1064539:Sp245p_RS05320
uniprot id: G8AEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1064539:Sp245p RS15905
gene id: 1064539:Sp245p_RS15905
uniprot id: G8AQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1064539:Sp245p RS33950
gene id: 1064539:Sp245p_RS33950
uniprot id: G8AZI3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1064539:Sp245p RS10050
gene id: 1064539:Sp245p_RS10050
uniprot id: G8AKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS09440
gene id: 1064539:Sp245p_RS09440
uniprot id: G8AL80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1064539:Sp245p RS15990
gene id: 1064539:Sp245p_RS15990
uniprot id: G8AQ83
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS25350
gene id: 1064539:Sp245p_RS25350
uniprot id: G8AYP5
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Hexamer of two alpha, two beta, and two delta chains.

1064539:Sp245p RS00570
gene id: 1064539:Sp245p_RS00570
uniprot id: G8AH02
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1064539:Sp245p RS33805
gene id: 1064539:Sp245p_RS33805
uniprot id: G8AZF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS33115
gene id: 1064539:Sp245p_RS33115
uniprot id: G8AZ11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS21720
gene id: 1064539:Sp245p_RS21720
uniprot id: G8ANV5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1064539:Sp245p RS34460
gene id: 1064539:Sp245p_RS34460
uniprot id: G8AZU7
names: Similarity
messages: Belongs to the aldose epimerase family.

1064539:Sp245p RS05865
gene id: 1064539:Sp245p_RS05865
uniprot id: G8ANK0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1064539:Sp245p RS09895
gene id: 1064539:Sp245p_RS09895
uniprot id: G8AKX9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS12925
gene id: 1064539:Sp245p_RS12925
uniprot id: G8AIY6
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

1064539:Sp245p RS17220
gene id: 1064539:Sp245p_RS17220
uniprot id: G8AR25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS29410
gene id: 1064539:Sp245p_RS29410
uniprot id: G8AWA4
names: Similarity
messages: Belongs to the citrate synthase family.

1064539:Sp245p RS08905
gene id: 1064539:Sp245p_RS08905
uniprot id: G8ALJ7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS26660
gene id: 1064539:Sp245p_RS26660
uniprot id: G8B178
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

1064539:Sp245p RS10175
gene id: 1064539:Sp245p_RS10175
uniprot id: G8AKS0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS11405
gene id: 1064539:Sp245p_RS11405
uniprot id: G8AJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS07935
gene id: 1064539:Sp245p_RS07935
uniprot id: G8AMR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1064539:Sp245p RS32370
gene id: 1064539:Sp245p_RS32370
uniprot id: G8B0Q6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1064539:Sp245p RS00685
gene id: 1064539:Sp245p_RS00685
uniprot id: G8AGG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1064539:Sp245p RS34110
gene id: 1064539:Sp245p_RS34110
uniprot id: G8AZM2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1064539:Sp245p RS02000
gene id: 1064539:Sp245p_RS02000
uniprot id: G8AF57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1064539:Sp245p RS32020
gene id: 1064539:Sp245p_RS32020
uniprot id: G8B0D7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1064539:Sp245p RS15215
gene id: 1064539:Sp245p_RS15215
uniprot id: G8APR0
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS33860
gene id: 1064539:Sp245p_RS33860
uniprot id: G8AZG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1064539:Sp245p RS12750
gene id: 1064539:Sp245p_RS12750
uniprot id: G8AJ26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1064539:Sp245p RS16310
gene id: 1064539:Sp245p_RS16310
uniprot id: G8AQG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS13180
gene id: 1064539:Sp245p_RS13180
uniprot id: G8AIS8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1064539:Sp245p RS13000
gene id: 1064539:Sp245p_RS13000
uniprot id: G8AIW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS20945
gene id: 1064539:Sp245p_RS20945
uniprot id: G8ATJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS06945
gene id: 1064539:Sp245p_RS06945
uniprot id: G8AM32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS25795
gene id: 1064539:Sp245p_RS25795
uniprot id: G8AYF0
names: Similarity
messages: Belongs to the MT-A70-like family.

1064539:Sp245p RS04485
gene id: 1064539:Sp245p_RS04485
uniprot id: G8AFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS25340
gene id: 1064539:Sp245p_RS25340
uniprot id: G8AYP7
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1064539:Sp245p RS31190
gene id: 1064539:Sp245p_RS31190
uniprot id: G8B0T8
names: Function
messages: Multidrug efflux pump.

1064539:Sp245p RS32875
gene id: 1064539:Sp245p_RS32875
uniprot id: G8AYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS07915
gene id: 1064539:Sp245p_RS07915
uniprot id: G8AMQ8
names: Similarity
messages: Belongs to the UPF0174 family.

1064539:Sp245p RS10085
gene id: 1064539:Sp245p_RS10085
uniprot id: G8AKT9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1064539:Sp245p RS28945
gene id: 1064539:Sp245p_RS28945
uniprot id: G8AVZ0
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1064539:Sp245p RS10130
gene id: 1064539:Sp245p_RS10130
uniprot id: G8AKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1064539:Sp245p RS26720
gene id: 1064539:Sp245p_RS26720
uniprot id: G8B1I8
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1064539:Sp245p RS02740
gene id: 1064539:Sp245p_RS02740
uniprot id: G8AE85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS21645
gene id: 1064539:Sp245p_RS21645
uniprot id: G8ANU0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1064539:Sp245p RS24220
gene id: 1064539:Sp245p_RS24220
uniprot id: G8AX32
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS07575
gene id: 1064539:Sp245p_RS07575
uniprot id: G8AMH9
names: Similarity
messages: Belongs to the manganese catalase family.

1064539:Sp245p RS34385
gene id: 1064539:Sp245p_RS34385
uniprot id: G8AZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1064539:Sp245p RS15425
gene id: 1064539:Sp245p_RS15425
uniprot id: G8APV7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1064539:Sp245p RS08240
gene id: 1064539:Sp245p_RS08240
uniprot id: G8ALZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1064539:Sp245p RS02355
gene id: 1064539:Sp245p_RS02355
uniprot id: G8AEG8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS07685
gene id: 1064539:Sp245p_RS07685
uniprot id: G8AMK2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1064539:Sp245p RS33935
gene id: 1064539:Sp245p_RS33935
uniprot id: G8AZH9
names: Similarity
messages: Belongs to the acylphosphatase family.

1064539:Sp245p RS34355
gene id: 1064539:Sp245p_RS34355
uniprot id: G8AZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1064539:Sp245p RS13600
gene id: 1064539:Sp245p_RS13600
uniprot id: G8AIH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS06075
gene id: 1064539:Sp245p_RS06075
uniprot id: G8ANF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1064539:Sp245p RS30725
gene id: 1064539:Sp245p_RS30725
uniprot id: G8B134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1064539:Sp245p RS21570
gene id: 1064539:Sp245p_RS21570
uniprot id: G8ANS4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1064539:Sp245p RS26375
gene id: 1064539:Sp245p_RS26375
uniprot id: G8B1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS10460
gene id: 1064539:Sp245p_RS10460
uniprot id: G8AKK9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1064539:Sp245p RS24240
gene id: 1064539:Sp245p_RS24240
uniprot id: G8AX28
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1064539:Sp245p RS05735
gene id: 1064539:Sp245p_RS05735
uniprot id: G8AEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1064539:Sp245p RS10950
gene id: 1064539:Sp245p_RS10950
uniprot id: G8AK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1064539:Sp245p RS24255
gene id: 1064539:Sp245p_RS24255
uniprot id: G8AX24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1064539:Sp245p RS32950
gene id: 1064539:Sp245p_RS32950
uniprot id: G8AYX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS29655
gene id: 1064539:Sp245p_RS29655
uniprot id: G8ATU6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS21940
gene id: 1064539:Sp245p_RS21940
uniprot id: G8AP00
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS17160
gene id: 1064539:Sp245p_RS17160
uniprot id: G8AR14
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18110
gene id: 1064539:Sp245p_RS18110
uniprot id: G8ARM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1064539:Sp245p RS10955
gene id: 1064539:Sp245p_RS10955
uniprot id: G8AK93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS20955
gene id: 1064539:Sp245p_RS20955
uniprot id: G8ATJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS16750
gene id: 1064539:Sp245p_RS16750
uniprot id: G8AQS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1064539:Sp245p RS10645
gene id: 1064539:Sp245p_RS10645
uniprot id: G8AKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS27595
gene id: 1064539:Sp245p_RS27595
uniprot id: G8AV05
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1064539:Sp245p RS23330
gene id: 1064539:Sp245p_RS23330
uniprot id: G8AXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS27165
gene id: 1064539:Sp245p_RS27165
uniprot id: G8AUQ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1064539:Sp245p RS00600
gene id: 1064539:Sp245p_RS00600
uniprot id: G8AGZ6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1064539:Sp245p RS19200
gene id: 1064539:Sp245p_RS19200
uniprot id: G8ASF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS17080
gene id: 1064539:Sp245p_RS17080
uniprot id: G8AQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS09860
gene id: 1064539:Sp245p_RS09860
uniprot id: G8AKY6
names: Similarity
messages: Belongs to the Skp family.

1064539:Sp245p RS07050
gene id: 1064539:Sp245p_RS07050
uniprot id: G8AM56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS25380
gene id: 1064539:Sp245p_RS25380
uniprot id: G8AYN8
names: Similarity
messages: Belongs to the NifX/NifY family.

1064539:Sp245p RS27255
gene id: 1064539:Sp245p_RS27255
uniprot id: G8AUS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS33000
gene id: 1064539:Sp245p_RS33000
uniprot id: G8AYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

1064539:Sp245p RS19525
gene id: 1064539:Sp245p_RS19525
uniprot id: G8ASM5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18650
gene id: 1064539:Sp245p_RS18650
uniprot id: G8AS05
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1064539:Sp245p RS13820
gene id: 1064539:Sp245p_RS13820
uniprot id: G8AI88
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS20385
gene id: 1064539:Sp245p_RS20385
uniprot id: G8AT66
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1064539:Sp245p RS20635
gene id: 1064539:Sp245p_RS20635
uniprot id: G8ATC1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1064539:Sp245p RS09735
gene id: 1064539:Sp245p_RS09735
uniprot id: G8AL13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1064539:Sp245p RS22830
gene id: 1064539:Sp245p_RS22830
uniprot id: G8AY02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1064539:Sp245p RS08555
gene id: 1064539:Sp245p_RS08555
uniprot id: G8ALT0
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1064539:Sp245p RS19460
gene id: 1064539:Sp245p_RS19460
uniprot id: G8ASL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS19960
gene id: 1064539:Sp245p_RS19960
uniprot id: G8ASW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1064539:Sp245p RS04860
gene id: 1064539:Sp245p_RS04860
uniprot id: G8AFN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1064539:Sp245p RS04895
gene id: 1064539:Sp245p_RS04895
uniprot id: G8AFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS23280
gene id: 1064539:Sp245p_RS23280
uniprot id: G8AXQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS32115
gene id: 1064539:Sp245p_RS32115
uniprot id: G8B0E2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1064539:Sp245p RS11720
gene id: 1064539:Sp245p_RS11720
uniprot id: G8AJR3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1064539:Sp245p RS09805
gene id: 1064539:Sp245p_RS09805
uniprot id: G8AKZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS15495
gene id: 1064539:Sp245p_RS15495
uniprot id: G8APX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1064539:Sp245p RS33565
gene id: 1064539:Sp245p_RS33565
uniprot id: G8AZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS12775
gene id: 1064539:Sp245p_RS12775
uniprot id: G8AJ20
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1064539:Sp245p RS15490
gene id: 1064539:Sp245p_RS15490
uniprot id: G8APX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1064539:Sp245p RS06525
gene id: 1064539:Sp245p_RS06525
uniprot id: G8AN49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1064539:Sp245p RS17720
gene id: 1064539:Sp245p_RS17720
uniprot id: G8ARE3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS33550
gene id: 1064539:Sp245p_RS33550
uniprot id: G8AZ94
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS21010
gene id: 1064539:Sp245p_RS21010
uniprot id: G8ATK4
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS05535
gene id: 1064539:Sp245p_RS05535
uniprot id: G8AER2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1064539:Sp245p RS12115
gene id: 1064539:Sp245p_RS12115
uniprot id: G8AJH3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1064539:Sp245p RS21360
gene id: 1064539:Sp245p_RS21360
uniprot id: G8ANM2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1064539:Sp245p RS35580
gene id: 1064539:Sp245p_RS35580
uniprot id: G8AEA1
names: Similarity
messages: Belongs to the SDHAF4 family.

1064539:Sp245p RS14055
gene id: 1064539:Sp245p_RS14055
uniprot id: G8AI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS17880
gene id: 1064539:Sp245p_RS17880
uniprot id: G8ARH9
names: Similarity
messages: Belongs to the peptidase S11 family.

1064539:Sp245p RS13145
gene id: 1064539:Sp245p_RS13145
uniprot id: G8AIT7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1064539:Sp245p RS09590
gene id: 1064539:Sp245p_RS09590
uniprot id: G8AL47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS11670
gene id: 1064539:Sp245p_RS11670
uniprot id: G8AJS3
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1064539:Sp245p RS16670
gene id: 1064539:Sp245p_RS16670
uniprot id: G8AQQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1064539:Sp245p RS19360
gene id: 1064539:Sp245p_RS19360
uniprot id: G8ASI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS11830
gene id: 1064539:Sp245p_RS11830
uniprot id: G8AJP0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS26820
gene id: 1064539:Sp245p_RS26820
uniprot id: G8AUH5
names: Similarity
messages: Belongs to the DapA family.

1064539:Sp245p RS17400
gene id: 1064539:Sp245p_RS17400
uniprot id: G8AR73
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1064539:Sp245p RS01355
gene id: 1064539:Sp245p_RS01355
uniprot id: G8AG18
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1064539:Sp245p RS09695
gene id: 1064539:Sp245p_RS09695
uniprot id: G8AL22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1064539:Sp245p RS03040
gene id: 1064539:Sp245p_RS03040
uniprot id: G8AIC9
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1064539:Sp245p RS14765
gene id: 1064539:Sp245p_RS14765
uniprot id: G8APG6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1064539:Sp245p RS01115
gene id: 1064539:Sp245p_RS01115
uniprot id: G8AG71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1064539:Sp245p RS19350
gene id: 1064539:Sp245p_RS19350
uniprot id: G8ASI6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS10640
gene id: 1064539:Sp245p_RS10640
uniprot id: G8AKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1064539:Sp245p RS06115
gene id: 1064539:Sp245p_RS06115
uniprot id: G8ANE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1064539:Sp245p RS21610
gene id: 1064539:Sp245p_RS21610
uniprot id: G8ANT3
names: Subcellular Location Annotation
messages: Cytoplasm

1064539:Sp245p RS23260
gene id: 1064539:Sp245p_RS23260
uniprot id: G8AXQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS20225
gene id: 1064539:Sp245p_RS20225
uniprot id: G8AT30
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1064539:Sp245p RS00675
gene id: 1064539:Sp245p_RS00675
uniprot id: G8AGY1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1064539:Sp245p RS30375
gene id: 1064539:Sp245p_RS30375
uniprot id: G8AUC1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS07890
gene id: 1064539:Sp245p_RS07890
uniprot id: G8AMQ3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1064539:Sp245p RS34375
gene id: 1064539:Sp245p_RS34375
uniprot id: G8AZT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1064539:Sp245p RS10775
gene id: 1064539:Sp245p_RS10775
uniprot id: G8AKD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1064539:Sp245p RS20210
gene id: 1064539:Sp245p_RS20210
uniprot id: G8AT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1064539:Sp245p RS16680
gene id: 1064539:Sp245p_RS16680
uniprot id: G8AQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1064539:Sp245p RS17465
gene id: 1064539:Sp245p_RS17465
uniprot id: G8AR86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1064539:Sp245p RS21200
gene id: 1064539:Sp245p_RS21200
uniprot id: G8ATP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS33085
gene id: 1064539:Sp245p_RS33085
uniprot id: G8AZ05
names: Similarity
messages: Belongs to the peptidase S41A family.

1064539:Sp245p RS13195
gene id: 1064539:Sp245p_RS13195
uniprot id: G8AIS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1064539:Sp245p RS07860
gene id: 1064539:Sp245p_RS07860
uniprot id: G8AMP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS19580
gene id: 1064539:Sp245p_RS19580
uniprot id: G8ASN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS29620
gene id: 1064539:Sp245p_RS29620
uniprot id: G8ATT6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS34240
gene id: 1064539:Sp245p_RS34240
uniprot id: G8AZQ0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1064539:Sp245p RS24620
gene id: 1064539:Sp245p_RS24620
uniprot id: G8AWU0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS10700
gene id: 1064539:Sp245p_RS10700
uniprot id: G8AKF5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1064539:Sp245p RS09010
gene id: 1064539:Sp245p_RS09010
uniprot id: G8ALH1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1064539:Sp245p RS08350
gene id: 1064539:Sp245p_RS08350
uniprot id: G8ALX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS11480
gene id: 1064539:Sp245p_RS11480
uniprot id: G8AJW7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1064539:Sp245p RS20305
gene id: 1064539:Sp245p_RS20305
uniprot id: G8AT49
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1064539:Sp245p RS24595
gene id: 1064539:Sp245p_RS24595
uniprot id: G8AWU7
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS18635
gene id: 1064539:Sp245p_RS18635
uniprot id: G8AS02
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1064539:Sp245p RS01675
gene id: 1064539:Sp245p_RS01675
uniprot id: G8AFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS14060
gene id: 1064539:Sp245p_RS14060
uniprot id: G8AI31
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1064539:Sp245p RS01960
gene id: 1064539:Sp245p_RS01960
uniprot id: G8AF68
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1064539:Sp245p RS03920
gene id: 1064539:Sp245p_RS03920
uniprot id: G8AGT9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS05985
gene id: 1064539:Sp245p_RS05985
uniprot id: G8ANH3
names: Subcellular Location Annotation
messages: Periplasm

1064539:Sp245p RS18370
gene id: 1064539:Sp245p_RS18370
uniprot id: G8ART6
names: Similarity
messages: Belongs to the peptidase M16 family.

1064539:Sp245p RS08475
gene id: 1064539:Sp245p_RS08475
uniprot id: G8ALU5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1064539:Sp245p RS01995
gene id: 1064539:Sp245p_RS01995
uniprot id: G8AF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1064539:Sp245p RS23200
gene id: 1064539:Sp245p_RS23200
uniprot id: G8AXS0
names: Similarity
messages: Belongs to the GST superfamily.

1064539:Sp245p RS04100
gene id: 1064539:Sp245p_RS04100
uniprot id: G8AGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS13230
gene id: 1064539:Sp245p_RS13230
uniprot id: G8AIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1064539:Sp245p RS12800
gene id: 1064539:Sp245p_RS12800
uniprot id: G8AJ14
names: Similarity
messages: Belongs to the SfsA family.

1064539:Sp245p RS01630
gene id: 1064539:Sp245p_RS01630
uniprot id: G8AFE4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS09315
gene id: 1064539:Sp245p_RS09315
uniprot id: G8ALA8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1064539:Sp245p RS22960
gene id: 1064539:Sp245p_RS22960
uniprot id: G8AXX5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1064539:Sp245p RS20265
gene id: 1064539:Sp245p_RS20265
uniprot id: G8AT39
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27810
gene id: 1064539:Sp245p_RS27810
uniprot id: G8AV69
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1064539:Sp245p RS15345
gene id: 1064539:Sp245p_RS15345
uniprot id: G8APT8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS09835
gene id: 1064539:Sp245p_RS09835
uniprot id: G8AKZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1064539:Sp245p RS32430
gene id: 1064539:Sp245p_RS32430
uniprot id: G8B0P0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS10785
gene id: 1064539:Sp245p_RS10785
uniprot id: G8AKD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1064539:Sp245p RS33200
gene id: 1064539:Sp245p_RS33200
uniprot id: G8AZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS13575
gene id: 1064539:Sp245p_RS13575
uniprot id: G8AII4
names: Similarity
messages: Belongs to the GST superfamily.

1064539:Sp245p RS21330
gene id: 1064539:Sp245p_RS21330
uniprot id: G8ANL7
names: Similarity
messages: Belongs to the MotB family.

1064539:Sp245p RS08065
gene id: 1064539:Sp245p_RS08065
uniprot id: G8AMU0
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS21035
gene id: 1064539:Sp245p_RS21035
uniprot id: G8ATL0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS18445
gene id: 1064539:Sp245p_RS18445
uniprot id: G8ARV4
names: Similarity
messages: Belongs to the UPF0111 family.

1064539:Sp245p RS00460
gene id: 1064539:Sp245p_RS00460
uniprot id: G8AH30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS02500
gene id: 1064539:Sp245p_RS02500
uniprot id: G8AED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS08520
gene id: 1064539:Sp245p_RS08520
uniprot id: G8ALT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS29860
gene id: 1064539:Sp245p_RS29860
uniprot id: G8ATZ7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1064539:Sp245p RS00200
gene id: 1064539:Sp245p_RS00200
uniprot id: G8AH87
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1064539:Sp245p RS15195
gene id: 1064539:Sp245p_RS15195
uniprot id: G8APQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS06090
gene id: 1064539:Sp245p_RS06090
uniprot id: G8ANE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1064539:Sp245p RS06900
gene id: 1064539:Sp245p_RS06900
uniprot id: G8AM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1064539:Sp245p RS21470
gene id: 1064539:Sp245p_RS21470
uniprot id: G8ANP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS06625
gene id: 1064539:Sp245p_RS06625
uniprot id: G8AN28
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1064539:Sp245p RS20230
gene id: 1064539:Sp245p_RS20230
uniprot id: G8AT31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1064539:Sp245p RS26580
gene id: 1064539:Sp245p_RS26580
uniprot id: G8B194
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS11570
gene id: 1064539:Sp245p_RS11570
uniprot id: G8AJU5
names: Similarity
messages: Belongs to the NifZ family.

1064539:Sp245p RS14260
gene id: 1064539:Sp245p_RS14260
uniprot id: G8AHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1064539:Sp245p RS02455
gene id: 1064539:Sp245p_RS02455
uniprot id: G8AEE7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1064539:Sp245p RS15960
gene id: 1064539:Sp245p_RS15960
uniprot id: G8AQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS02175
gene id: 1064539:Sp245p_RS02175
uniprot id: G8AF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS24665
gene id: 1064539:Sp245p_RS24665
uniprot id: G8AWT1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1064539:Sp245p RS05485
gene id: 1064539:Sp245p_RS05485
uniprot id: G8AES3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS19380
gene id: 1064539:Sp245p_RS19380
uniprot id: G8ASJ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1064539:Sp245p RS02655
gene id: 1064539:Sp245p_RS02655
uniprot id: G8AEA3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS33690
gene id: 1064539:Sp245p_RS33690
uniprot id: G8AZC8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS18310
gene id: 1064539:Sp245p_RS18310
uniprot id: G8ARS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1064539:Sp245p RS24590
gene id: 1064539:Sp245p_RS24590
uniprot id: G8AWU8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27535
gene id: 1064539:Sp245p_RS27535
uniprot id: G8AUY9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1064539:Sp245p RS20825
gene id: 1064539:Sp245p_RS20825
uniprot id: G8ATG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1064539:Sp245p RS03290
gene id: 1064539:Sp245p_RS03290
uniprot id: G8AHQ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1064539:Sp245p RS18135
gene id: 1064539:Sp245p_RS18135
uniprot id: G8ARN3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS13435
gene id: 1064539:Sp245p_RS13435
uniprot id: G8AIM1
names: Similarity
messages: Belongs to the peptidase M17 family.

1064539:Sp245p RS21405
gene id: 1064539:Sp245p_RS21405
uniprot id: G8ANN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS29315
gene id: 1064539:Sp245p_RS29315
uniprot id: G8AW76
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS29990
gene id: 1064539:Sp245p_RS29990
uniprot id: G8AU30
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1064539:Sp245p RS08335
gene id: 1064539:Sp245p_RS08335
uniprot id: G8ALX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1064539:Sp245p RS27500
gene id: 1064539:Sp245p_RS27500
uniprot id: G8AUY1
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS28040
gene id: 1064539:Sp245p_RS28040
uniprot id: G8AVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1064539:Sp245p RS13330
gene id: 1064539:Sp245p_RS13330
uniprot id: G8AIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1064539:Sp245p RS27770
gene id: 1064539:Sp245p_RS27770
uniprot id: G8AV59
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1064539:Sp245p RS02965
gene id: 1064539:Sp245p_RS02965
uniprot id: G8AIE5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1064539:Sp245p RS13695
gene id: 1064539:Sp245p_RS13695
uniprot id: G8AIB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1064539:Sp245p RS31875
gene id: 1064539:Sp245p_RS31875
uniprot id: G8B0A8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1064539:Sp245p RS17525
gene id: 1064539:Sp245p_RS17525
uniprot id: G8AR99
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1064539:Sp245p RS16965
gene id: 1064539:Sp245p_RS16965
uniprot id: G8AQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS19985
gene id: 1064539:Sp245p_RS19985
uniprot id: G8ASX1
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1064539:Sp245p RS32175
gene id: 1064539:Sp245p_RS32175
uniprot id: G8B0F6
names: Similarity
messages: Belongs to the MotB family.

1064539:Sp245p RS02240
gene id: 1064539:Sp245p_RS02240
uniprot id: G8AEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS23460
gene id: 1064539:Sp245p_RS23460
uniprot id: G8AXL2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS11790
gene id: 1064539:Sp245p_RS11790
uniprot id: G8AJP7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS27570
gene id: 1064539:Sp245p_RS27570
uniprot id: G8AUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1064539:Sp245p RS23985
gene id: 1064539:Sp245p_RS23985
uniprot id: G8AX84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS27820
gene id: 1064539:Sp245p_RS27820
uniprot id: G8AV71
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1064539:Sp245p RS34530
gene id: 1064539:Sp245p_RS34530
uniprot id: G8AZW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS08835
gene id: 1064539:Sp245p_RS08835
uniprot id: G8ALL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS07925
gene id: 1064539:Sp245p_RS07925
uniprot id: G8AMR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1064539:Sp245p RS26325
gene id: 1064539:Sp245p_RS26325
uniprot id: G8B1E6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1064539:Sp245p RS13565
gene id: 1064539:Sp245p_RS13565
uniprot id: G8AII7
names: Similarity
messages: Belongs to the universal stress protein A family.

1064539:Sp245p RS12000
gene id: 1064539:Sp245p_RS12000
uniprot id: G8AJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS21480
gene id: 1064539:Sp245p_RS21480
uniprot id: G8ANP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1064539:Sp245p RS18205
gene id: 1064539:Sp245p_RS18205
uniprot id: G8ARQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1064539:Sp245p RS13775
gene id: 1064539:Sp245p_RS13775
uniprot id: G8AI98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1064539:Sp245p RS05755
gene id: 1064539:Sp245p_RS05755
uniprot id: G8AEL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1064539:Sp245p RS11760
gene id: 1064539:Sp245p_RS11760
uniprot id: G8AJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1064539:Sp245p RS02010
gene id: 1064539:Sp245p_RS02010
uniprot id: G8AF55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1064539:Sp245p RS02150
gene id: 1064539:Sp245p_RS02150
uniprot id: G8AF23
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS33675
gene id: 1064539:Sp245p_RS33675
uniprot id: G8AZC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1064539:Sp245p RS16440
gene id: 1064539:Sp245p_RS16440
uniprot id: G8AQJ9
names: Subcellular Location Annotation
messages: Virion

1064539:Sp245p RS09395
gene id: 1064539:Sp245p_RS09395
uniprot id: G8AL90
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS14835
gene id: 1064539:Sp245p_RS14835
uniprot id: G8APH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS08800
gene id: 1064539:Sp245p_RS08800
uniprot id: G8ALL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1064539:Sp245p RS00955
gene id: 1064539:Sp245p_RS00955
uniprot id: G8AGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS29040
gene id: 1064539:Sp245p_RS29040
uniprot id: G8AW11
names: Similarity
messages: Belongs to the FemABX family.

1064539:Sp245p RS18225
gene id: 1064539:Sp245p_RS18225
uniprot id: G8ARQ5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1064539:Sp245p RS05325
gene id: 1064539:Sp245p_RS05325
uniprot id: G8AEW0
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1064539:Sp245p RS13060
gene id: 1064539:Sp245p_RS13060
uniprot id: G8AIV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS33260
gene id: 1064539:Sp245p_RS33260
uniprot id: G8AZ50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS11925
gene id: 1064539:Sp245p_RS11925
uniprot id: G8AJL6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1064539:Sp245p RS24540
gene id: 1064539:Sp245p_RS24540
uniprot id: G8AWV9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS01305
gene id: 1064539:Sp245p_RS01305
uniprot id: G8AG28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1064539:Sp245p RS19585
gene id: 1064539:Sp245p_RS19585
uniprot id: G8ASN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS18500
gene id: 1064539:Sp245p_RS18500
uniprot id: G8ARX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS02035
gene id: 1064539:Sp245p_RS02035
uniprot id: G8AF47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS06185
gene id: 1064539:Sp245p_RS06185
uniprot id: G8ANC7
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS03170
gene id: 1064539:Sp245p_RS03170
uniprot id: G8AHT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1064539:Sp245p RS22530
gene id: 1064539:Sp245p_RS22530
uniprot id: G8AY72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS00340
gene id: 1064539:Sp245p_RS00340
uniprot id: G8AH61
names: Similarity
messages: Belongs to the PspA/IM30 family.

1064539:Sp245p RS15470
gene id: 1064539:Sp245p_RS15470
uniprot id: G8APW7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1064539:Sp245p RS13065
gene id: 1064539:Sp245p_RS13065
uniprot id: G8AIV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1064539:Sp245p RS06270
gene id: 1064539:Sp245p_RS06270
uniprot id: G8ANA9
names: Similarity
messages: Belongs to the ArsC family.

1064539:Sp245p RS08405
gene id: 1064539:Sp245p_RS08405
uniprot id: G8ALW2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1064539:Sp245p RS06865
gene id: 1064539:Sp245p_RS06865
uniprot id: G8AM15
names: Similarity
messages: Belongs to the CapA family.

1064539:Sp245p RS11710
gene id: 1064539:Sp245p_RS11710
uniprot id: G8AJR5
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1064539:Sp245p RS18680
gene id: 1064539:Sp245p_RS18680
uniprot id: G8AS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS10340
gene id: 1064539:Sp245p_RS10340
uniprot id: G8AKN5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1064539:Sp245p RS05380
gene id: 1064539:Sp245p_RS05380
uniprot id: G8AEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1064539:Sp245p RS00430
gene id: 1064539:Sp245p_RS00430
uniprot id: G8AH38
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1064539:Sp245p RS10585
gene id: 1064539:Sp245p_RS10585
uniprot id: G8AKI0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1064539:Sp245p RS27045
gene id: 1064539:Sp245p_RS27045
uniprot id: G8AUM5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS10000
gene id: 1064539:Sp245p_RS10000
uniprot id: G8AKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1064539:Sp245p RS33630
gene id: 1064539:Sp245p_RS33630
uniprot id: G8AZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1064539:Sp245p RS24430
gene id: 1064539:Sp245p_RS24430
uniprot id: G8AWY3
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1064539:Sp245p RS01080
gene id: 1064539:Sp245p_RS01080
uniprot id: G8AG78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS08080
gene id: 1064539:Sp245p_RS08080
uniprot id: G8AMU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS00730
gene id: 1064539:Sp245p_RS00730
uniprot id: G8AGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1064539:Sp245p RS34525
gene id: 1064539:Sp245p_RS34525
uniprot id: G8AZW1
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

1064539:Sp245p RS23130
gene id: 1064539:Sp245p_RS23130
uniprot id: G8AXT6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS00865
gene id: 1064539:Sp245p_RS00865
uniprot id: G8AGC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1064539:Sp245p RS00560
gene id: 1064539:Sp245p_RS00560
uniprot id: G8AH04
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS00260
gene id: 1064539:Sp245p_RS00260
uniprot id: G8AH75
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS02100
gene id: 1064539:Sp245p_RS02100
uniprot id: G8AF32
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS25790
gene id: 1064539:Sp245p_RS25790
uniprot id: G8AYF2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1064539:Sp245p RS10520
gene id: 1064539:Sp245p_RS10520
uniprot id: G8AKJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1064539:Sp245p RS02710
gene id: 1064539:Sp245p_RS02710
uniprot id: G8AE92
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS04635
gene id: 1064539:Sp245p_RS04635
uniprot id: G8AFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1064539:Sp245p RS16615
gene id: 1064539:Sp245p_RS16615
uniprot id: G8AQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1064539:Sp245p RS01370
gene id: 1064539:Sp245p_RS01370
uniprot id: G8AG15
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1064539:Sp245p RS26690
gene id: 1064539:Sp245p_RS26690
uniprot id: G8B1K0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS33810
gene id: 1064539:Sp245p_RS33810
uniprot id: G8AZF2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1064539:Sp245p RS14115
gene id: 1064539:Sp245p_RS14115
uniprot id: G8AI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1064539:Sp245p RS32805
gene id: 1064539:Sp245p_RS32805
uniprot id: G8AYU4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1064539:Sp245p RS16030
gene id: 1064539:Sp245p_RS16030
uniprot id: G8AQ90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS24530
gene id: 1064539:Sp245p_RS24530
uniprot id: G8AWW1
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS32840
gene id: 1064539:Sp245p_RS32840
uniprot id: G8AYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS25260
gene id: 1064539:Sp245p_RS25260
uniprot id: G8AYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS17970
gene id: 1064539:Sp245p_RS17970
uniprot id: G8ARJ9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS03625
gene id: 1064539:Sp245p_RS03625
uniprot id: G8AHH5
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1064539:Sp245p RS19040
gene id: 1064539:Sp245p_RS19040
uniprot id: G8ASA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1064539:Sp245p RS27605
gene id: 1064539:Sp245p_RS27605
uniprot id: G8AV07
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS01395
gene id: 1064539:Sp245p_RS01395
uniprot id: G8AG09
names: Similarity
messages: Belongs to the ros/MucR family.

1064539:Sp245p RS07425
gene id: 1064539:Sp245p_RS07425
uniprot id: G8AME5
names: Similarity
messages: Belongs to the YjdM family.

1064539:Sp245p RS01290
gene id: 1064539:Sp245p_RS01290
uniprot id: G8AG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS22725
gene id: 1064539:Sp245p_RS22725
uniprot id: G8AY25
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS34370
gene id: 1064539:Sp245p_RS34370
uniprot id: G8AZS9
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS09105
gene id: 1064539:Sp245p_RS09105
uniprot id: G8ALE8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1064539:Sp245p RS34165
gene id: 1064539:Sp245p_RS34165
uniprot id: G8AZN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS14465
gene id: 1064539:Sp245p_RS14465
uniprot id: G8APA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS15815
gene id: 1064539:Sp245p_RS15815
uniprot id: G8AQ43
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS21820
gene id: 1064539:Sp245p_RS21820
uniprot id: G8ANX4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1064539:Sp245p RS29445
gene id: 1064539:Sp245p_RS29445
uniprot id: G8AWB3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1064539:Sp245p RS05360
gene id: 1064539:Sp245p_RS05360
uniprot id: G8AEV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1064539:Sp245p RS17055
gene id: 1064539:Sp245p_RS17055
uniprot id: G8AQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS05840
gene id: 1064539:Sp245p_RS05840
uniprot id: G8ANK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1064539:Sp245p RS08400
gene id: 1064539:Sp245p_RS08400
uniprot id: G8ALW3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1064539:Sp245p RS26630
gene id: 1064539:Sp245p_RS26630
uniprot id: G8B184
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1064539:Sp245p RS05260
gene id: 1064539:Sp245p_RS05260
uniprot id: G8AEX4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1064539:Sp245p RS07785
gene id: 1064539:Sp245p_RS07785
uniprot id: G8AMN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1064539:Sp245p RS03915
gene id: 1064539:Sp245p_RS03915
uniprot id: G8AGU0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS21930
gene id: 1064539:Sp245p_RS21930
uniprot id: G8ANZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1064539:Sp245p RS33965
gene id: 1064539:Sp245p_RS33965
uniprot id: G8AZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS08965
gene id: 1064539:Sp245p_RS08965
uniprot id: G8ALI2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS04890
gene id: 1064539:Sp245p_RS04890
uniprot id: G8AFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1064539:Sp245p RS29930
gene id: 1064539:Sp245p_RS29930
uniprot id: G8AU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1064539:Sp245p RS24115
gene id: 1064539:Sp245p_RS24115
uniprot id: G8AX54
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1064539:Sp245p RS05690
gene id: 1064539:Sp245p_RS05690
uniprot id: G8AEM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1064539:Sp245p RS12825
gene id: 1064539:Sp245p_RS12825
uniprot id: G8AJ09
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1064539:Sp245p RS00960
gene id: 1064539:Sp245p_RS00960
uniprot id: G8AGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS03945
gene id: 1064539:Sp245p_RS03945
uniprot id: G8AGT2
names: Similarity
messages: Belongs to the XFP family.

1064539:Sp245p RS09295
gene id: 1064539:Sp245p_RS09295
uniprot id: G8ALB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1064539:Sp245p RS05200
gene id: 1064539:Sp245p_RS05200
uniprot id: G8AEY6
names: Similarity
messages: Belongs to the RNase T2 family.

1064539:Sp245p RS10375
gene id: 1064539:Sp245p_RS10375
uniprot id: G8AKM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1064539:Sp245p RS00720
gene id: 1064539:Sp245p_RS00720
uniprot id: G8AGF6
names: Similarity
messages: Belongs to the UPF0162 family.

1064539:Sp245p RS29690
gene id: 1064539:Sp245p_RS29690
uniprot id: G8ATV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS34150
gene id: 1064539:Sp245p_RS34150
uniprot id: G8AZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1064539:Sp245p RS24930
gene id: 1064539:Sp245p_RS24930
uniprot id: G8AWL6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1064539:Sp245p RS31415
gene id: 1064539:Sp245p_RS31415
uniprot id: G8B006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS15660
gene id: 1064539:Sp245p_RS15660
uniprot id: G8AQ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1064539:Sp245p RS20200
gene id: 1064539:Sp245p_RS20200
uniprot id: G8AT24
names: Similarity
messages: Belongs to the aspartokinase family.

1064539:Sp245p RS08760
gene id: 1064539:Sp245p_RS08760
uniprot id: G8ALM7
names: Similarity
messages: Belongs to the virb1 family.

1064539:Sp245p RS02130
gene id: 1064539:Sp245p_RS02130
uniprot id: G8AF27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1064539:Sp245p RS22255
gene id: 1064539:Sp245p_RS22255
uniprot id: G8AP82
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1064539:Sp245p RS15410
gene id: 1064539:Sp245p_RS15410
uniprot id: G8APV4
names: Similarity
messages: Belongs to the universal stress protein A family.

1064539:Sp245p RS06785
gene id: 1064539:Sp245p_RS06785
uniprot id: G8AMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1064539:Sp245p RS19445
gene id: 1064539:Sp245p_RS19445
uniprot id: G8ASK7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS08285
gene id: 1064539:Sp245p_RS08285
uniprot id: G8ALY7
names: Similarity
messages: Belongs to the ros/MucR family.

1064539:Sp245p RS09415
gene id: 1064539:Sp245p_RS09415
uniprot id: G8AL85
names: Subcellular Location Annotation
messages: Cytoplasm

1064539:Sp245p RS00595
gene id: 1064539:Sp245p_RS00595
uniprot id: G8AGZ7
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1064539:Sp245p RS02760
gene id: 1064539:Sp245p_RS02760
uniprot id: G8AE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS05315
gene id: 1064539:Sp245p_RS05315
uniprot id: G8AEW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS16185
gene id: 1064539:Sp245p_RS16185
uniprot id: G8AQD4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1064539:Sp245p RS28790
gene id: 1064539:Sp245p_RS28790
uniprot id: G8AVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS24235
gene id: 1064539:Sp245p_RS24235
uniprot id: G8AX29
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

1064539:Sp245p RS18830
gene id: 1064539:Sp245p_RS18830
uniprot id: G8AS48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS12940
gene id: 1064539:Sp245p_RS12940
uniprot id: G8AIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS33685
gene id: 1064539:Sp245p_RS33685
uniprot id: G8AZC6
names: Similarity
messages: Belongs to the FemABX family.

1064539:Sp245p RS10725
gene id: 1064539:Sp245p_RS10725
uniprot id: G8AKE8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS09840
gene id: 1064539:Sp245p_RS09840
uniprot id: G8AKZ0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1064539:Sp245p RS13745
gene id: 1064539:Sp245p_RS13745
uniprot id: G8AIA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1064539:Sp245p RS16900
gene id: 1064539:Sp245p_RS16900
uniprot id: G8AQV8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS26420
gene id: 1064539:Sp245p_RS26420
uniprot id: G8B1C7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS16775
gene id: 1064539:Sp245p_RS16775
uniprot id: G8AQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1064539:Sp245p RS09555
gene id: 1064539:Sp245p_RS09555
uniprot id: G8AL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS31835
gene id: 1064539:Sp245p_RS31835
uniprot id: G8B096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS17670
gene id: 1064539:Sp245p_RS17670
uniprot id: G8ARD1
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1064539:Sp245p RS32360
gene id: 1064539:Sp245p_RS32360
uniprot id: G8B0Q9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS18360
gene id: 1064539:Sp245p_RS18360
uniprot id: G8ART4
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1064539:Sp245p RS14760
gene id: 1064539:Sp245p_RS14760
uniprot id: G8APG5
names: Similarity
messages: Belongs to the ModE family.

1064539:Sp245p RS00415
gene id: 1064539:Sp245p_RS00415
uniprot id: G8AH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1064539:Sp245p RS33150
gene id: 1064539:Sp245p_RS33150
uniprot id: G8AZ19
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1064539:Sp245p RS34360
gene id: 1064539:Sp245p_RS34360
uniprot id: G8AZS6
names: Subcellular Location Annotation
messages: Mitochondrion

1064539:Sp245p RS06220
gene id: 1064539:Sp245p_RS06220
uniprot id: G8ANC0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1064539:Sp245p RS01475
gene id: 1064539:Sp245p_RS01475
uniprot id: G8AFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1064539:Sp245p RS28925
gene id: 1064539:Sp245p_RS28925
uniprot id: G8AVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS15985
gene id: 1064539:Sp245p_RS15985
uniprot id: G8AQ82
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1064539:Sp245p RS18955
gene id: 1064539:Sp245p_RS18955
uniprot id: G8AS74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1064539:Sp245p RS18390
gene id: 1064539:Sp245p_RS18390
uniprot id: G8ARU2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1064539:Sp245p RS23860
gene id: 1064539:Sp245p_RS23860
uniprot id: G8AXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS33155
gene id: 1064539:Sp245p_RS33155
uniprot id: G8AZ20
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1064539:Sp245p RS14565
gene id: 1064539:Sp245p_RS14565
uniprot id: G8APC4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1064539:Sp245p RS03335
gene id: 1064539:Sp245p_RS03335
uniprot id: G8AHP4
names: Subcellular Location Annotation
messages: Virion

1064539:Sp245p RS10110
gene id: 1064539:Sp245p_RS10110
uniprot id: G8AKT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS02975
gene id: 1064539:Sp245p_RS02975
uniprot id: G8AIE3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1064539:Sp245p RS30230
gene id: 1064539:Sp245p_RS30230
uniprot id: G8AU87
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS16755
gene id: 1064539:Sp245p_RS16755
uniprot id: G8AQS5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS08420
gene id: 1064539:Sp245p_RS08420
uniprot id: G8ALV8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS16155
gene id: 1064539:Sp245p_RS16155
uniprot id: G8AQC4
names: Similarity
messages: Belongs to the HesB/IscA family.

1064539:Sp245p RS09945
gene id: 1064539:Sp245p_RS09945
uniprot id: G8AKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1064539:Sp245p RS22070
gene id: 1064539:Sp245p_RS22070
uniprot id: G8AP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1064539:Sp245p RS29855
gene id: 1064539:Sp245p_RS29855
uniprot id: G8ATZ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS01165
gene id: 1064539:Sp245p_RS01165
uniprot id: G8AG59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1064539:Sp245p RS08870
gene id: 1064539:Sp245p_RS08870
uniprot id: G8ALK4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1064539:Sp245p RS02600
gene id: 1064539:Sp245p_RS02600
uniprot id: G8AEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1064539:Sp245p RS29585
gene id: 1064539:Sp245p_RS29585
uniprot id: G8AWE9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS23300
gene id: 1064539:Sp245p_RS23300
uniprot id: G8AXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS26450
gene id: 1064539:Sp245p_RS26450
uniprot id: G8B1C1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1064539:Sp245p RS28735
gene id: 1064539:Sp245p_RS28735
uniprot id: G8AVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS06930
gene id: 1064539:Sp245p_RS06930
uniprot id: G8AM29
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS15755
gene id: 1064539:Sp245p_RS15755
uniprot id: G8AQ30
names: Function
messages: Acts on leucine, isoleucine and valine.

1064539:Sp245p RS26285
gene id: 1064539:Sp245p_RS26285
uniprot id: G8B1F5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1064539:Sp245p RS24025
gene id: 1064539:Sp245p_RS24025
uniprot id: G8AX75
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1064539:Sp245p RS13705
gene id: 1064539:Sp245p_RS13705
uniprot id: G8AIB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1064539:Sp245p RS15895
gene id: 1064539:Sp245p_RS15895
uniprot id: G8AQ61
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS15235
gene id: 1064539:Sp245p_RS15235
uniprot id: G8APR5
names: Similarity
messages: Belongs to the UPF0234 family.

1064539:Sp245p RS21905
gene id: 1064539:Sp245p_RS21905
uniprot id: G8ANZ3
names: Similarity
messages: Belongs to the Gfa family.

1064539:Sp245p RS09715
gene id: 1064539:Sp245p_RS09715
uniprot id: G8AL18
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS09675
gene id: 1064539:Sp245p_RS09675
uniprot id: G8AL26
names: Similarity
messages: Belongs to the PqqA family.

1064539:Sp245p RS33615
gene id: 1064539:Sp245p_RS33615
uniprot id: G8AZA8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS08675
gene id: 1064539:Sp245p_RS08675
uniprot id: G8ALQ1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1064539:Sp245p RS12315
gene id: 1064539:Sp245p_RS12315
uniprot id: G8AJC1
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS01740
gene id: 1064539:Sp245p_RS01740
uniprot id: G8AFB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1064539:Sp245p RS28815
gene id: 1064539:Sp245p_RS28815
uniprot id: G8AVW0
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1064539:Sp245p RS19890
gene id: 1064539:Sp245p_RS19890
uniprot id: G8ASU6
names: Similarity
messages: Belongs to the peptidase C40 family.

1064539:Sp245p RS10005
gene id: 1064539:Sp245p_RS10005
uniprot id: G8AKV6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1064539:Sp245p RS14335
gene id: 1064539:Sp245p_RS14335
uniprot id: G8AHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1064539:Sp245p RS06670
gene id: 1064539:Sp245p_RS06670
uniprot id: G8AN18
names: Similarity
messages: Belongs to the threonine synthase family.

1064539:Sp245p RS02055
gene id: 1064539:Sp245p_RS02055
uniprot id: G8AF42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1064539:Sp245p RS32535
gene id: 1064539:Sp245p_RS32535
uniprot id: G8B0L7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1064539:Sp245p RS13400
gene id: 1064539:Sp245p_RS13400
uniprot id: G8AIM8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1064539:Sp245p RS06005
gene id: 1064539:Sp245p_RS06005
uniprot id: G8ANG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS27375
gene id: 1064539:Sp245p_RS27375
uniprot id: G8AUV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS07705
gene id: 1064539:Sp245p_RS07705
uniprot id: G8AML0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1064539:Sp245p RS34025
gene id: 1064539:Sp245p_RS34025
uniprot id: G8AZJ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS24865
gene id: 1064539:Sp245p_RS24865
uniprot id: G8AWN5
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS09450
gene id: 1064539:Sp245p_RS09450
uniprot id: G8AL77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1064539:Sp245p RS34070
gene id: 1064539:Sp245p_RS34070
uniprot id: G8AZL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1064539:Sp245p RS13955
gene id: 1064539:Sp245p_RS13955
uniprot id: G8AI58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1064539:Sp245p RS17565
gene id: 1064539:Sp245p_RS17565
uniprot id: G8ARA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1064539:Sp245p RS07750
gene id: 1064539:Sp245p_RS07750
uniprot id: G8AMM2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1064539:Sp245p RS20545
gene id: 1064539:Sp245p_RS20545
uniprot id: G8AT99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1064539:Sp245p RS34075
gene id: 1064539:Sp245p_RS34075
uniprot id: G8AZL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1064539:Sp245p RS31460
gene id: 1064539:Sp245p_RS31460
uniprot id: G8B014
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS02675
gene id: 1064539:Sp245p_RS02675
uniprot id: G8AEA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS27155
gene id: 1064539:Sp245p_RS27155
uniprot id: G8AUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1064539:Sp245p RS29715
gene id: 1064539:Sp245p_RS29715
uniprot id: G8ATV9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1064539:Sp245p RS29375
gene id: 1064539:Sp245p_RS29375
uniprot id: G8AW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS07065
gene id: 1064539:Sp245p_RS07065
uniprot id: G8AM60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1064539:Sp245p RS33680
gene id: 1064539:Sp245p_RS33680
uniprot id: G8AZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1064539:Sp245p RS28165
gene id: 1064539:Sp245p_RS28165
uniprot id: G8AVF1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1064539:Sp245p RS06800
gene id: 1064539:Sp245p_RS06800
uniprot id: G8AMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1064539:Sp245p RS00645
gene id: 1064539:Sp245p_RS00645
uniprot id: G8AGY7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1064539:Sp245p RS13170
gene id: 1064539:Sp245p_RS13170
uniprot id: G8AIT0
names: Similarity
messages: Belongs to the peptidase S41A family.

1064539:Sp245p RS26415
gene id: 1064539:Sp245p_RS26415
uniprot id: G8B1C8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS17185
gene id: 1064539:Sp245p_RS17185
uniprot id: G8AR19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1064539:Sp245p RS14610
gene id: 1064539:Sp245p_RS14610
uniprot id: G8APD3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1064539:Sp245p RS24845
gene id: 1064539:Sp245p_RS24845
uniprot id: G8AWN9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS17820
gene id: 1064539:Sp245p_RS17820
uniprot id: G8ARG3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1064539:Sp245p RS12090
gene id: 1064539:Sp245p_RS12090
uniprot id: G8AJI0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1064539:Sp245p RS27615
gene id: 1064539:Sp245p_RS27615
uniprot id: G8AV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS23050
gene id: 1064539:Sp245p_RS23050
uniprot id: G8AXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS01040
gene id: 1064539:Sp245p_RS01040
uniprot id: G8AG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1064539:Sp245p RS13270
gene id: 1064539:Sp245p_RS13270
uniprot id: G8AIQ7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1064539:Sp245p RS29295
gene id: 1064539:Sp245p_RS29295
uniprot id: G8AW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1064539:Sp245p RS33915
gene id: 1064539:Sp245p_RS33915
uniprot id: G8AZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1064539:Sp245p RS31965
gene id: 1064539:Sp245p_RS31965
uniprot id: G8B0C7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1064539:Sp245p RS17675
gene id: 1064539:Sp245p_RS17675
uniprot id: G8ARD2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS12485
gene id: 1064539:Sp245p_RS12485
uniprot id: G8AJ82
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1064539:Sp245p RS24505
gene id: 1064539:Sp245p_RS24505
uniprot id: G8AWW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS06895
gene id: 1064539:Sp245p_RS06895
uniprot id: G8AM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1064539:Sp245p RS20275
gene id: 1064539:Sp245p_RS20275
uniprot id: G8AT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1064539:Sp245p RS21945
gene id: 1064539:Sp245p_RS21945
uniprot id: G8AP01
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1064539:Sp245p RS08235
gene id: 1064539:Sp245p_RS08235
uniprot id: G8ALZ8
names: Similarity
messages: Belongs to the MoaD family.

1064539:Sp245p RS20675
gene id: 1064539:Sp245p_RS20675
uniprot id: G8ATC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1064539:Sp245p RS11380
gene id: 1064539:Sp245p_RS11380
uniprot id: G8AJY8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1064539:Sp245p RS12845
gene id: 1064539:Sp245p_RS12845
uniprot id: G8AJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1064539:Sp245p RS21300
gene id: 1064539:Sp245p_RS21300
uniprot id: G8ATS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1064539:Sp245p RS11840
gene id: 1064539:Sp245p_RS11840
uniprot id: G8AJN8
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1064539:Sp245p RS12970
gene id: 1064539:Sp245p_RS12970
uniprot id: G8AIX6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1064539:Sp245p RS33330
gene id: 1064539:Sp245p_RS33330
uniprot id: G8AMY1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1064539:Sp245p RS03975
gene id: 1064539:Sp245p_RS03975
uniprot id: G8AGS4
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS05155
gene id: 1064539:Sp245p_RS05155
uniprot id: G8AEZ4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS20850
gene id: 1064539:Sp245p_RS20850
uniprot id: G8ATH2
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1064539:Sp245p RS25490
gene id: 1064539:Sp245p_RS25490
uniprot id: G8AYM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1064539:Sp245p RS25575
gene id: 1064539:Sp245p_RS25575
uniprot id: G8AYK2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS10160
gene id: 1064539:Sp245p_RS10160
uniprot id: G8AKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1064539:Sp245p RS21785
gene id: 1064539:Sp245p_RS21785
uniprot id: G8ANW7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1064539:Sp245p RS04665
gene id: 1064539:Sp245p_RS04665
uniprot id: G8AFT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1064539:Sp245p RS00585
gene id: 1064539:Sp245p_RS00585
uniprot id: G8AGZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1064539:Sp245p RS27435
gene id: 1064539:Sp245p_RS27435
uniprot id: G8AUW6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS22575
gene id: 1064539:Sp245p_RS22575
uniprot id: G8AY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1064539:Sp245p RS15550
gene id: 1064539:Sp245p_RS15550
uniprot id: G8APY6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS02890
gene id: 1064539:Sp245p_RS02890
uniprot id: G8AIG1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1064539:Sp245p RS30415
gene id: 1064539:Sp245p_RS30415
uniprot id: G8AUD8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1064539:Sp245p RS07315
gene id: 1064539:Sp245p_RS07315
uniprot id: G8AMC0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1064539:Sp245p RS03130
gene id: 1064539:Sp245p_RS03130
uniprot id: G8AHU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1064539:Sp245p RS18730
gene id: 1064539:Sp245p_RS18730
uniprot id: G8AS22
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1064539:Sp245p RS01440
gene id: 1064539:Sp245p_RS01440
uniprot id: G8AFZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1064539:Sp245p RS32755
gene id: 1064539:Sp245p_RS32755
uniprot id: G8AYT2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS11090
gene id: 1064539:Sp245p_RS11090
uniprot id: G8AK61
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1064539:Sp245p RS32000
gene id: 1064539:Sp245p_RS32000
uniprot id: G8B0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1064539:Sp245p RS06665
gene id: 1064539:Sp245p_RS06665
uniprot id: G8AN19
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1064539:Sp245p RS15720
gene id: 1064539:Sp245p_RS15720
uniprot id: G8AQ21
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1064539:Sp245p RS33755
gene id: 1064539:Sp245p_RS33755
uniprot id: G8AZD6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS08810
gene id: 1064539:Sp245p_RS08810
uniprot id: G8ALL6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1064539:Sp245p RS27365
gene id: 1064539:Sp245p_RS27365
uniprot id: G8AUV1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1064539:Sp245p RS10975
gene id: 1064539:Sp245p_RS10975
uniprot id: G8AK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1064539:Sp245p RS29070
gene id: 1064539:Sp245p_RS29070
uniprot id: G8AW20
names: Similarity
messages: Belongs to the ParB family.

1064539:Sp245p RS19590
gene id: 1064539:Sp245p_RS19590
uniprot id: G8ASN9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS13645
gene id: 1064539:Sp245p_RS13645
uniprot id: G8AIG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS20880
gene id: 1064539:Sp245p_RS20880
uniprot id: G8ATH8
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1064539:Sp245p RS03015
gene id: 1064539:Sp245p_RS03015
uniprot id: G8AID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1064539:Sp245p RS14930
gene id: 1064539:Sp245p_RS14930
uniprot id: G8APJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS17990
gene id: 1064539:Sp245p_RS17990
uniprot id: G8ARK3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1064539:Sp245p RS20600
gene id: 1064539:Sp245p_RS20600
uniprot id: G8ATB4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1064539:Sp245p RS17180
gene id: 1064539:Sp245p_RS17180
uniprot id: G8AR18
names: Similarity
messages: Belongs to the DprA/Smf family.

1064539:Sp245p RS21210
gene id: 1064539:Sp245p_RS21210
uniprot id: G8ATQ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS19705
gene id: 1064539:Sp245p_RS19705
uniprot id: G8ASR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1064539:Sp245p RS24020
gene id: 1064539:Sp245p_RS24020
uniprot id: G8AX76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1064539:Sp245p RS05695
gene id: 1064539:Sp245p_RS05695
uniprot id: G8AEM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1064539:Sp245p RS06715
gene id: 1064539:Sp245p_RS06715
uniprot id: G8AN09
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1064539:Sp245p RS31580
gene id: 1064539:Sp245p_RS31580
uniprot id: G8B042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1064539:Sp245p RS10795
gene id: 1064539:Sp245p_RS10795
uniprot id: G8AKD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1064539:Sp245p RS25280
gene id: 1064539:Sp245p_RS25280
uniprot id: G8AYR1
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1064539:Sp245p RS07940
gene id: 1064539:Sp245p_RS07940
uniprot id: G8AMR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1064539:Sp245p RS09825
gene id: 1064539:Sp245p_RS09825
uniprot id: G8AKZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS01855
gene id: 1064539:Sp245p_RS01855
uniprot id: G8AF92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS01235
gene id: 1064539:Sp245p_RS01235
uniprot id: G8AG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1064539:Sp245p RS26275
gene id: 1064539:Sp245p_RS26275
uniprot id: G8B1F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1064539:Sp245p RS34505
gene id: 1064539:Sp245p_RS34505
uniprot id: G8AZV6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS23925
gene id: 1064539:Sp245p_RS23925
uniprot id: G8AX99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS10380
gene id: 1064539:Sp245p_RS10380
uniprot id: G8AKM7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1064539:Sp245p RS06050
gene id: 1064539:Sp245p_RS06050
uniprot id: G8ANF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1064539:Sp245p RS20655
gene id: 1064539:Sp245p_RS20655
uniprot id: G8ATC5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1064539:Sp245p RS17110
gene id: 1064539:Sp245p_RS17110
uniprot id: G8AR03
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

1064539:Sp245p RS16260
gene id: 1064539:Sp245p_RS16260
uniprot id: G8AQF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1064539:Sp245p RS10675
gene id: 1064539:Sp245p_RS10675
uniprot id: G8AKG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS06605
gene id: 1064539:Sp245p_RS06605
uniprot id: G8AN32
names: Similarity
messages: Belongs to the peptidase U62 family.

1064539:Sp245p RS17965
gene id: 1064539:Sp245p_RS17965
uniprot id: G8ARJ8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS12210
gene id: 1064539:Sp245p_RS12210
uniprot id: G8AJE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS09220
gene id: 1064539:Sp245p_RS09220
uniprot id: G8ALC1
names: Similarity
messages: Belongs to the hyi family.

1064539:Sp245p RS34265
gene id: 1064539:Sp245p_RS34265
uniprot id: G8AZQ6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1064539:Sp245p RS25045
gene id: 1064539:Sp245p_RS25045
uniprot id: G8AWJ8
names: Similarity
messages: Belongs to the arginase family.

1064539:Sp245p RS10810
gene id: 1064539:Sp245p_RS10810
uniprot id: G8AKD1
names: Similarity
messages: Belongs to the UPF0335 family.

1064539:Sp245p RS15540
gene id: 1064539:Sp245p_RS15540
uniprot id: G8APY4
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1064539:Sp245p RS21880
gene id: 1064539:Sp245p_RS21880
uniprot id: G8ANY8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1064539:Sp245p RS11070
gene id: 1064539:Sp245p_RS11070
uniprot id: G8AK66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1064539:Sp245p RS22555
gene id: 1064539:Sp245p_RS22555
uniprot id: G8AY66
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1064539:Sp245p RS00150
gene id: 1064539:Sp245p_RS00150
uniprot id: G8AH98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS25120
gene id: 1064539:Sp245p_RS25120
uniprot id: G8AWH4
names: Similarity
messages: Belongs to the isochorismate synthase family.

1064539:Sp245p RS10020
gene id: 1064539:Sp245p_RS10020
uniprot id: G8AKV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS21420
gene id: 1064539:Sp245p_RS21420
uniprot id: G8ANN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

1064539:Sp245p RS10545
gene id: 1064539:Sp245p_RS10545
uniprot id: G8AKI9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS26640
gene id: 1064539:Sp245p_RS26640
uniprot id: G8B182
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1064539:Sp245p RS32710
gene id: 1064539:Sp245p_RS32710
uniprot id: G8B0I1
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS02260
gene id: 1064539:Sp245p_RS02260
uniprot id: G8AEI9
names: Similarity
messages: Belongs to the UPF0235 family.

1064539:Sp245p RS29090
gene id: 1064539:Sp245p_RS29090
uniprot id: G8AW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS11690
gene id: 1064539:Sp245p_RS11690
uniprot id: G8AJR9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1064539:Sp245p RS01420
gene id: 1064539:Sp245p_RS01420
uniprot id: G8AG03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1064539:Sp245p RS04425
gene id: 1064539:Sp245p_RS04425
uniprot id: G8AFZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS08385
gene id: 1064539:Sp245p_RS08385
uniprot id: G8ALW6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1064539:Sp245p RS20480
gene id: 1064539:Sp245p_RS20480
uniprot id: G8AT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1064539:Sp245p RS28080
gene id: 1064539:Sp245p_RS28080
uniprot id: G8AVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

1064539:Sp245p RS05040
gene id: 1064539:Sp245p_RS05040
uniprot id: G8AFJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1064539:Sp245p RS21605
gene id: 1064539:Sp245p_RS21605
uniprot id: G8ANT2
names: Similarity
messages: Belongs to the UPF0225 family.

1064539:Sp245p RS01795
gene id: 1064539:Sp245p_RS01795
uniprot id: G8AFA5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1064539:Sp245p RS01505
gene id: 1064539:Sp245p_RS01505
uniprot id: G8AFH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1064539:Sp245p RS17735
gene id: 1064539:Sp245p_RS17735
uniprot id: G8ARE6
names: Subcellular Location Annotation
messages: Cytoplasm

1064539:Sp245p RS07570
gene id: 1064539:Sp245p_RS07570
uniprot id: G8AMH8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS06265
gene id: 1064539:Sp245p_RS06265
uniprot id: G8ANB0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1064539:Sp245p RS05780
gene id: 1064539:Sp245p_RS05780
uniprot id: G8AEK7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1064539:Sp245p RS16940
gene id: 1064539:Sp245p_RS16940
uniprot id: G8AQW6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1064539:Sp245p RS24535
gene id: 1064539:Sp245p_RS24535
uniprot id: G8AWW0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23580
gene id: 1064539:Sp245p_RS23580
uniprot id: G8AXI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05240
gene id: 1064539:Sp245p_RS05240
uniprot id: G8AEX8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1064539:Sp245p RS24805
gene id: 1064539:Sp245p_RS24805
uniprot id: G8AWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS20185
gene id: 1064539:Sp245p_RS20185
uniprot id: G8AT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1064539:Sp245p RS13580
gene id: 1064539:Sp245p_RS13580
uniprot id: G8AII3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS12140
gene id: 1064539:Sp245p_RS12140
uniprot id: G8AJG6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1064539:Sp245p RS07565
gene id: 1064539:Sp245p_RS07565
uniprot id: G8AMH7
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1064539:Sp245p RS18450
gene id: 1064539:Sp245p_RS18450
uniprot id: G8ARV5
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS25135
gene id: 1064539:Sp245p_RS25135
uniprot id: G8AWH0
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS25275
gene id: 1064539:Sp245p_RS25275
uniprot id: G8AYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1064539:Sp245p RS03780
gene id: 1064539:Sp245p_RS03780
uniprot id: G8AGX8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1064539:Sp245p RS22040
gene id: 1064539:Sp245p_RS22040
uniprot id: G8AP21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1064539:Sp245p RS07775
gene id: 1064539:Sp245p_RS07775
uniprot id: G8AMM8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS12920
gene id: 1064539:Sp245p_RS12920
uniprot id: G8AIY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1064539:Sp245p RS19840
gene id: 1064539:Sp245p_RS19840
uniprot id: G8AST6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05490
gene id: 1064539:Sp245p_RS05490
uniprot id: G8AES2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS13375
gene id: 1064539:Sp245p_RS13375
uniprot id: G8AIN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS12810
gene id: 1064539:Sp245p_RS12810
uniprot id: G8AJ12
names: Similarity
messages: Belongs to the UPF0758 family.

1064539:Sp245p RS14440
gene id: 1064539:Sp245p_RS14440
uniprot id: G8AP98
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS20460
gene id: 1064539:Sp245p_RS20460
uniprot id: G8AT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1064539:Sp245p RS03710
gene id: 1064539:Sp245p_RS03710
uniprot id: G8AHF5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS03265
gene id: 1064539:Sp245p_RS03265
uniprot id: G8AHQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS16960
gene id: 1064539:Sp245p_RS16960
uniprot id: G8AQX0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1064539:Sp245p RS35570
gene id: 1064539:Sp245p_RS35570
uniprot id: G8AEE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS14050
gene id: 1064539:Sp245p_RS14050
uniprot id: G8AI34
names: Similarity
messages: Belongs to the pirin family.

1064539:Sp245p RS08295
gene id: 1064539:Sp245p_RS08295
uniprot id: G8ALY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1064539:Sp245p RS32810
gene id: 1064539:Sp245p_RS32810
uniprot id: G8AYU5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1064539:Sp245p RS20930
gene id: 1064539:Sp245p_RS20930
uniprot id: G8ATI8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1064539:Sp245p RS15300
gene id: 1064539:Sp245p_RS15300
uniprot id: G8APS8
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23950
gene id: 1064539:Sp245p_RS23950
uniprot id: G8AX92
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1064539:Sp245p RS08485
gene id: 1064539:Sp245p_RS08485
uniprot id: G8ALU3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1064539:Sp245p RS18485
gene id: 1064539:Sp245p_RS18485
uniprot id: G8ARW9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS19860
gene id: 1064539:Sp245p_RS19860
uniprot id: G8ASU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS07675
gene id: 1064539:Sp245p_RS07675
uniprot id: G8AMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1064539:Sp245p RS19475
gene id: 1064539:Sp245p_RS19475
uniprot id: G8ASL3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS34180
gene id: 1064539:Sp245p_RS34180
uniprot id: G8AZN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1064539:Sp245p RS06310
gene id: 1064539:Sp245p_RS06310
uniprot id: G8AN98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1064539:Sp245p RS23780
gene id: 1064539:Sp245p_RS23780
uniprot id: G8AXD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1064539:Sp245p RS03160
gene id: 1064539:Sp245p_RS03160
uniprot id: G8AHT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1064539:Sp245p RS08980
gene id: 1064539:Sp245p_RS08980
uniprot id: G8ALH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1064539:Sp245p RS09750
gene id: 1064539:Sp245p_RS09750
uniprot id: G8AL10
names: Subcellular Location Annotation
messages: Cell membrane

1064539:Sp245p RS03180
gene id: 1064539:Sp245p_RS03180
uniprot id: G8AHT2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1064539:Sp245p RS30145
gene id: 1064539:Sp245p_RS30145
uniprot id: G8AU68
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS05080
gene id: 1064539:Sp245p_RS05080
uniprot id: G8AF13
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1064539:Sp245p RS05995
gene id: 1064539:Sp245p_RS05995
uniprot id: G8ANH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1064539:Sp245p RS32750
gene id: 1064539:Sp245p_RS32750
uniprot id: G8AYT1
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS04245
gene id: 1064539:Sp245p_RS04245
uniprot id: G8AGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1064539:Sp245p RS19630
gene id: 1064539:Sp245p_RS19630
uniprot id: G8ASP6
names: Similarity
messages: Belongs to the peptidase S13 family.

1064539:Sp245p RS25130
gene id: 1064539:Sp245p_RS25130
uniprot id: G8AWH1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS10365
gene id: 1064539:Sp245p_RS10365
uniprot id: G8AKN0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1064539:Sp245p RS12840
gene id: 1064539:Sp245p_RS12840
uniprot id: G8AJ05
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1064539:Sp245p RS22045
gene id: 1064539:Sp245p_RS22045
uniprot id: G8AP22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1064539:Sp245p RS04760
gene id: 1064539:Sp245p_RS04760
uniprot id: G8AFQ2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1064539:Sp245p RS09670
gene id: 1064539:Sp245p_RS09670
uniprot id: G8AL27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1064539:Sp245p RS19140
gene id: 1064539:Sp245p_RS19140
uniprot id: G8ASD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1064539:Sp245p RS28120
gene id: 1064539:Sp245p_RS28120
uniprot id: G8AVE2
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1064539:Sp245p RS04865
gene id: 1064539:Sp245p_RS04865
uniprot id: G8AFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1064539:Sp245p RS09795
gene id: 1064539:Sp245p_RS09795
uniprot id: G8AL01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1064539:Sp245p RS20950
gene id: 1064539:Sp245p_RS20950
uniprot id: G8ATJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS18520
gene id: 1064539:Sp245p_RS18520
uniprot id: G8ARX8
names: Similarity
messages: Belongs to the SlyX family.

1064539:Sp245p RS35780
gene id: 1064539:Sp245p_RS35780
uniprot id: G8AQR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1064539:Sp245p RS20315
gene id: 1064539:Sp245p_RS20315
uniprot id: G8AT51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1064539:Sp245p RS33365
gene id: 1064539:Sp245p_RS33365
uniprot id: G8AMX5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1064539:Sp245p RS08330
gene id: 1064539:Sp245p_RS08330
uniprot id: G8ALX8
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1064539:Sp245p RS28650
gene id: 1064539:Sp245p_RS28650
uniprot id: G8AVS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS13325
gene id: 1064539:Sp245p_RS13325
uniprot id: G8AIP4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1064539:Sp245p RS21555
gene id: 1064539:Sp245p_RS21555
uniprot id: G8ANS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1064539:Sp245p RS12975
gene id: 1064539:Sp245p_RS12975
uniprot id: G8AIX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS23145
gene id: 1064539:Sp245p_RS23145
uniprot id: G8AXT3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1064539:Sp245p RS05790
gene id: 1064539:Sp245p_RS05790
uniprot id: G8AEK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1064539:Sp245p RS24150
gene id: 1064539:Sp245p_RS24150
uniprot id: G8AX47
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS01195
gene id: 1064539:Sp245p_RS01195
uniprot id: G8AG52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1064539:Sp245p RS01490
gene id: 1064539:Sp245p_RS01490
uniprot id: G8AFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1064539:Sp245p RS00680
gene id: 1064539:Sp245p_RS00680
uniprot id: G8AGG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1064539:Sp245p RS30250
gene id: 1064539:Sp245p_RS30250
uniprot id: G8AU91
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1064539:Sp245p RS13910
gene id: 1064539:Sp245p_RS13910
uniprot id: G8AI68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1064539:Sp245p RS18645
gene id: 1064539:Sp245p_RS18645
uniprot id: G8AS04
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1064539:Sp245p RS29455
gene id: 1064539:Sp245p_RS29455
uniprot id: G8AWB5
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1064539:Sp245p RS09400
gene id: 1064539:Sp245p_RS09400
uniprot id: G8AL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS33090
gene id: 1064539:Sp245p_RS33090
uniprot id: G8AZ06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS10010
gene id: 1064539:Sp245p_RS10010
uniprot id: G8AKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1064539:Sp245p RS00545
gene id: 1064539:Sp245p_RS00545
uniprot id: G8AH08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1064539:Sp245p RS33575
gene id: 1064539:Sp245p_RS33575
uniprot id: G8AZA0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1064539:Sp245p RS28700
gene id: 1064539:Sp245p_RS28700
uniprot id: G8AVT6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1064539:Sp245p RS13840
gene id: 1064539:Sp245p_RS13840
uniprot id: G8AI84
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1064539:Sp245p RS10580
gene id: 1064539:Sp245p_RS10580
uniprot id: G8AKI1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1064539:Sp245p RS11740
gene id: 1064539:Sp245p_RS11740
uniprot id: G8AJQ9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1064539:Sp245p RS02700
gene id: 1064539:Sp245p_RS02700
uniprot id: G8AE94
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1064539:Sp245p RS08270
gene id: 1064539:Sp245p_RS08270
uniprot id: G8ALZ0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS31955
gene id: 1064539:Sp245p_RS31955
uniprot id: G8B0C5
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1064539:Sp245p RS15920
gene id: 1064539:Sp245p_RS15920
uniprot id: G8AQ67
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1064539:Sp245p RS27035
gene id: 1064539:Sp245p_RS27035
uniprot id: G8AUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS04805
gene id: 1064539:Sp245p_RS04805
uniprot id: G8AFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1064539:Sp245p RS13755
gene id: 1064539:Sp245p_RS13755
uniprot id: G8AIA3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1064539:Sp245p RS28880
gene id: 1064539:Sp245p_RS28880
uniprot id: G8AVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1064539:Sp245p RS33030
gene id: 1064539:Sp245p_RS33030
uniprot id: G8AYZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1064539:Sp245p RS09240
gene id: 1064539:Sp245p_RS09240
uniprot id: G8ALB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1064539:Sp245p RS16035
gene id: 1064539:Sp245p_RS16035
uniprot id: G8AQ92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS11895
gene id: 1064539:Sp245p_RS11895
uniprot id: G8AJM3
names: Similarity
messages: Belongs to the SCO1/2 family.

1064539:Sp245p RS32120
gene id: 1064539:Sp245p_RS32120
uniprot id: G8B0E3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Periplasm

1064539:Sp245p RS13590
gene id: 1064539:Sp245p_RS13590
uniprot id: G8AII0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1064539:Sp245p RS06630
gene id: 1064539:Sp245p_RS06630
uniprot id: G8AN26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1064539:Sp245p RS14170
gene id: 1064539:Sp245p_RS14170
uniprot id: G8AI07
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS17320
gene id: 1064539:Sp245p_RS17320
uniprot id: G8AR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS34200
gene id: 1064539:Sp245p_RS34200
uniprot id: G8AZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS28810
gene id: 1064539:Sp245p_RS28810
uniprot id: G8AVV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS07670
gene id: 1064539:Sp245p_RS07670
uniprot id: G8AMJ8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1064539:Sp245p RS11745
gene id: 1064539:Sp245p_RS11745
uniprot id: G8AJQ8
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

1064539:Sp245p RS17840
gene id: 1064539:Sp245p_RS17840
uniprot id: G8ARG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1064539:Sp245p RS15980
gene id: 1064539:Sp245p_RS15980
uniprot id: G8AQ81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS15995
gene id: 1064539:Sp245p_RS15995
uniprot id: G8AQ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS22315
gene id: 1064539:Sp245p_RS22315
uniprot id: G8AP95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS18215
gene id: 1064539:Sp245p_RS18215
uniprot id: G8ARQ3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1064539:Sp245p RS30130
gene id: 1064539:Sp245p_RS30130
uniprot id: G8AU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS06070
gene id: 1064539:Sp245p_RS06070
uniprot id: G8ANF5
names: Similarity
messages: Belongs to the type III secretion exporter family.

1064539:Sp245p RS21595
gene id: 1064539:Sp245p_RS21595
uniprot id: G8ANT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1064539:Sp245p RS24470
gene id: 1064539:Sp245p_RS24470
uniprot id: G8AWX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS33255
gene id: 1064539:Sp245p_RS33255
uniprot id: G8AZ49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1064539:Sp245p RS15695
gene id: 1064539:Sp245p_RS15695
uniprot id: G8AQ16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1064539:Sp245p RS19660
gene id: 1064539:Sp245p_RS19660
uniprot id: G8ASQ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1064539:Sp245p RS15880
gene id: 1064539:Sp245p_RS15880
uniprot id: G8AQ58
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS32180
gene id: 1064539:Sp245p_RS32180
uniprot id: G8B0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

1064539:Sp245p RS23265
gene id: 1064539:Sp245p_RS23265
uniprot id: G8AXQ5
names: Similarity
messages: Belongs to the proline racemase family.

1064539:Sp245p RS02985
gene id: 1064539:Sp245p_RS02985
uniprot id: G8AIE1
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1064539:Sp245p RS19805
gene id: 1064539:Sp245p_RS19805
uniprot id: G8ASS8
names: Similarity
messages: Belongs to the peptidase S1B family.

1064539:Sp245p RS05585
gene id: 1064539:Sp245p_RS05585
uniprot id: G8AEP8
names: Similarity
messages: Belongs to the hemerythrin family.

1064539:Sp245p RS24340
gene id: 1064539:Sp245p_RS24340
uniprot id: G8AX03
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1064539:Sp245p RS29360
gene id: 1064539:Sp245p_RS29360
uniprot id: G8AW93
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS16125
gene id: 1064539:Sp245p_RS16125
uniprot id: G8AQB8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1064539:Sp245p RS21685
gene id: 1064539:Sp245p_RS21685
uniprot id: G8ANU8
names: Similarity
messages: Belongs to the peptidase A31 family.

1064539:Sp245p RS32160
gene id: 1064539:Sp245p_RS32160
uniprot id: G8B0F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1064539:Sp245p RS09325
gene id: 1064539:Sp245p_RS09325
uniprot id: G8ALA6
names: Similarity
messages: Belongs to the histone deacetylase family.

1064539:Sp245p RS30995
gene id: 1064539:Sp245p_RS30995
uniprot id: G8B0X6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1064539:Sp245p RS09875
gene id: 1064539:Sp245p_RS09875
uniprot id: G8AKY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS09770
gene id: 1064539:Sp245p_RS09770
uniprot id: G8AL06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS03085
gene id: 1064539:Sp245p_RS03085
uniprot id: G8AHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1064539:Sp245p RS09330
gene id: 1064539:Sp245p_RS09330
uniprot id: G8ALA4
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS08345
gene id: 1064539:Sp245p_RS08345
uniprot id: G8ALX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS06910
gene id: 1064539:Sp245p_RS06910
uniprot id: G8AM25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1064539:Sp245p RS30350
gene id: 1064539:Sp245p_RS30350
uniprot id: G8AUB5
names: Similarity
messages: Belongs to the histone deacetylase family.

1064539:Sp245p RS09635
gene id: 1064539:Sp245p_RS09635
uniprot id: G8AL36
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1064539:Sp245p RS24160
gene id: 1064539:Sp245p_RS24160
uniprot id: G8AX44
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS02640
gene id: 1064539:Sp245p_RS02640
uniprot id: G8AEA6
names: Similarity
messages: Belongs to the YciI family.

1064539:Sp245p RS28180
gene id: 1064539:Sp245p_RS28180
uniprot id: G8AVF7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1064539:Sp245p RS24415
gene id: 1064539:Sp245p_RS24415
uniprot id: G8AWY7
names: Similarity
messages: Belongs to the DapA family.

1064539:Sp245p RS26490
gene id: 1064539:Sp245p_RS26490
uniprot id: G8B1B2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1064539:Sp245p RS10230
gene id: 1064539:Sp245p_RS10230
uniprot id: G8AKQ9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1064539:Sp245p RS06085
gene id: 1064539:Sp245p_RS06085
uniprot id: G8ANF0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1064539:Sp245p RS02045
gene id: 1064539:Sp245p_RS02045
uniprot id: G8AF44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1064539:Sp245p RS16845
gene id: 1064539:Sp245p_RS16845
uniprot id: G8AQU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1064539:Sp245p RS07305
gene id: 1064539:Sp245p_RS07305
uniprot id: G8AMB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1064539:Sp245p RS06385
gene id: 1064539:Sp245p_RS06385
uniprot id: G8AN82
names: Similarity
messages: Belongs to the RutC family.

1064539:Sp245p RS11500
gene id: 1064539:Sp245p_RS11500
uniprot id: G8AJW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1064539:Sp245p RS13620
gene id: 1064539:Sp245p_RS13620
uniprot id: G8AIH4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1064539:Sp245p RS32480
gene id: 1064539:Sp245p_RS32480
uniprot id: G8B0M9
names: Similarity
messages: Belongs to the TPP enzyme family.

1064539:Sp245p RS06000
gene id: 1064539:Sp245p_RS06000
uniprot id: G8ANG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1064539:Sp245p RS03060
gene id: 1064539:Sp245p_RS03060
uniprot id: G8AIC5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1064539:Sp245p RS16815
gene id: 1064539:Sp245p_RS16815
uniprot id: G8AQU0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1064539:Sp245p RS12355
gene id: 1064539:Sp245p_RS12355
uniprot id: G8AJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS07320
gene id: 1064539:Sp245p_RS07320
uniprot id: G8AMC1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1064539:Sp245p RS07070
gene id: 1064539:Sp245p_RS07070
uniprot id: G8AM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1064539:Sp245p RS31570
gene id: 1064539:Sp245p_RS31570
uniprot id: G8B040
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS03505
gene id: 1064539:Sp245p_RS03505
uniprot id: G8AHK3
names: Similarity
messages: Belongs to the UPF0335 family.

1064539:Sp245p RS09460
gene id: 1064539:Sp245p_RS09460
uniprot id: G8AL75
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1064539:Sp245p RS21515
gene id: 1064539:Sp245p_RS21515
uniprot id: G8ANQ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1064539:Sp245p RS09110
gene id: 1064539:Sp245p_RS09110
uniprot id: G8ALE7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1064539:Sp245p RS14560
gene id: 1064539:Sp245p_RS14560
uniprot id: G8APC3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS27370
gene id: 1064539:Sp245p_RS27370
uniprot id: G8AUV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS33920
gene id: 1064539:Sp245p_RS33920
uniprot id: G8AZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1064539:Sp245p RS17470
gene id: 1064539:Sp245p_RS17470
uniprot id: G8AR87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS02775
gene id: 1064539:Sp245p_RS02775
uniprot id: G8AE77
names: Similarity
messages: Belongs to the PRORSD1 family.

1064539:Sp245p RS03910
gene id: 1064539:Sp245p_RS03910
uniprot id: G8AGU1
names: Similarity
messages: Belongs to the leucine-binding protein family.

1064539:Sp245p RS29100
gene id: 1064539:Sp245p_RS29100
uniprot id: G8AW26
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1064539:Sp245p RS17250
gene id: 1064539:Sp245p_RS17250
uniprot id: G8AR32
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS16480
gene id: 1064539:Sp245p_RS16480
uniprot id: G8AQK9
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1064539:Sp245p RS24695
gene id: 1064539:Sp245p_RS24695
uniprot id: G8AWS4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1064539:Sp245p RS14770
gene id: 1064539:Sp245p_RS14770
uniprot id: G8APG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1064539:Sp245p RS33020
gene id: 1064539:Sp245p_RS33020
uniprot id: G8AYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1064539:Sp245p RS21450
gene id: 1064539:Sp245p_RS21450
uniprot id: G8ANP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell inner membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1064539:Sp245p RS24400
gene id: 1064539:Sp245p_RS24400
uniprot id: G8AWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS34650
gene id: 1064539:Sp245p_RS34650
uniprot id: G8AZY6
names: Similarity
messages: Belongs to the UxaA family.

1064539:Sp245p RS01835
gene id: 1064539:Sp245p_RS01835
uniprot id: G8AF98
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1064539:Sp245p RS30325
gene id: 1064539:Sp245p_RS30325
uniprot id: G8AUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS05990
gene id: 1064539:Sp245p_RS05990
uniprot id: G8ANH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1064539:Sp245p RS02395
gene id: 1064539:Sp245p_RS02395
uniprot id: G8AEF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1064539:Sp245p RS08070
gene id: 1064539:Sp245p_RS08070
uniprot id: G8AMU2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1064539:Sp245p RS22085
gene id: 1064539:Sp245p_RS22085
uniprot id: G8AP31
names: Similarity
messages: Belongs to the histone deacetylase family.

1064539:Sp245p RS12400
gene id: 1064539:Sp245p_RS12400
uniprot id: G8AJA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1064539:Sp245p RS03200
gene id: 1064539:Sp245p_RS03200
uniprot id: G8AHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS11705
gene id: 1064539:Sp245p_RS11705
uniprot id: G8AJR6
names: Similarity
messages: Belongs to the HesB/IscA family. Ycf83 subfamily.

1064539:Sp245p RS34580
gene id: 1064539:Sp245p_RS34580
uniprot id: G8AZX0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1064539:Sp245p RS06780
gene id: 1064539:Sp245p_RS06780
uniprot id: G8AMZ3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1064539:Sp245p RS03720
gene id: 1064539:Sp245p_RS03720
uniprot id: G8AHF2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1064539:Sp245p RS30505
gene id: 1064539:Sp245p_RS30505
uniprot id: G8AUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1064539:Sp245p RS10035
gene id: 1064539:Sp245p_RS10035
uniprot id: G8AKV0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1064539:Sp245p RS12980
gene id: 1064539:Sp245p_RS12980
uniprot id: G8AIX3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1064539:Sp245p RS09215
gene id: 1064539:Sp245p_RS09215
uniprot id: G8ALC2
names: Similarity
messages: Belongs to the TPP enzyme family.

1064539:Sp245p RS10125
gene id: 1064539:Sp245p_RS10125
uniprot id: G8AKT2
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1064539:Sp245p RS15200
gene id: 1064539:Sp245p_RS15200
uniprot id: G8APQ7
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS13385
gene id: 1064539:Sp245p_RS13385
uniprot id: G8AIN1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1064539:Sp245p RS34440
gene id: 1064539:Sp245p_RS34440
uniprot id: G8AZU3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS11810
gene id: 1064539:Sp245p_RS11810
uniprot id: G8AJP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS16620
gene id: 1064539:Sp245p_RS16620
uniprot id: G8AQP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1064539:Sp245p RS17225
gene id: 1064539:Sp245p_RS17225
uniprot id: G8AR26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1064539:Sp245p RS14145
gene id: 1064539:Sp245p_RS14145
uniprot id: G8AI14
names: Similarity
messages: Belongs to the pirin family.

1064539:Sp245p RS27160
gene id: 1064539:Sp245p_RS27160
uniprot id: G8AUQ2
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS14015
gene id: 1064539:Sp245p_RS14015
uniprot id: G8AI44
names: Similarity
messages: Belongs to the BolA/IbaG family.

1064539:Sp245p RS05730
gene id: 1064539:Sp245p_RS05730
uniprot id: G8AEN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1064539:Sp245p RS30075
gene id: 1064539:Sp245p_RS30075
uniprot id: G8AU51
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1064539:Sp245p RS00605
gene id: 1064539:Sp245p_RS00605
uniprot id: G8AGZ5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1064539:Sp245p RS33610
gene id: 1064539:Sp245p_RS33610
uniprot id: G8AZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1064539:Sp245p RS16240
gene id: 1064539:Sp245p_RS16240
uniprot id: G8AQE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS22910
gene id: 1064539:Sp245p_RS22910
uniprot id: G8AXY6
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS25315
gene id: 1064539:Sp245p_RS25315
uniprot id: G8AYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1064539:Sp245p RS34645
gene id: 1064539:Sp245p_RS34645
uniprot id: G8AZY5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1064539:Sp245p RS06120
gene id: 1064539:Sp245p_RS06120
uniprot id: G8ANE1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1064539:Sp245p RS14215
gene id: 1064539:Sp245p_RS14215
uniprot id: G8AHZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1064539:Sp245p RS17505
gene id: 1064539:Sp245p_RS17505
uniprot id: G8AR94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS33790
gene id: 1064539:Sp245p_RS33790
uniprot id: G8AZE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS04735
gene id: 1064539:Sp245p_RS04735
uniprot id: G8AFQ8
names: Subcellular Location Annotation
messages: Cell inner membrane

1064539:Sp245p RS01950
gene id: 1064539:Sp245p_RS01950
uniprot id: G8AF71
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS23420
gene id: 1064539:Sp245p_RS23420
uniprot id: G8AXM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS03075
gene id: 1064539:Sp245p_RS03075
uniprot id: G8AHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS31675
gene id: 1064539:Sp245p_RS31675
uniprot id: G8B065
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS06675
gene id: 1064539:Sp245p_RS06675
uniprot id: G8AN17
names: Similarity
messages: Belongs to the peptidase M16 family.

1064539:Sp245p RS07125
gene id: 1064539:Sp245p_RS07125
uniprot id: G8AM73
names: Similarity
messages: Belongs to the DNA photolyase family.

1064539:Sp245p RS04250
gene id: 1064539:Sp245p_RS04250
uniprot id: G8AGK6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1064539:Sp245p RS24000
gene id: 1064539:Sp245p_RS24000
uniprot id: G8AX80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS03940
gene id: 1064539:Sp245p_RS03940
uniprot id: G8AGT3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1064539:Sp245p RS06485
gene id: 1064539:Sp245p_RS06485
uniprot id: G8AN58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1064539:Sp245p RS23425
gene id: 1064539:Sp245p_RS23425
uniprot id: G8AXL9
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1064539:Sp245p RS27075
gene id: 1064539:Sp245p_RS27075
uniprot id: G8AUN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS12945
gene id: 1064539:Sp245p_RS12945
uniprot id: G8AIY1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1064539:Sp245p RS10360
gene id: 1064539:Sp245p_RS10360
uniprot id: G8AKN1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1064539:Sp245p RS11850
gene id: 1064539:Sp245p_RS11850
uniprot id: G8AJN5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1064539:Sp245p RS07585
gene id: 1064539:Sp245p_RS07585
uniprot id: G8AMI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1064539:Sp245p RS07765
gene id: 1064539:Sp245p_RS07765
uniprot id: G8AMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1064539:Sp245p RS18435
gene id: 1064539:Sp245p_RS18435
uniprot id: G8ARV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1064539:Sp245p RS21620
gene id: 1064539:Sp245p_RS21620
uniprot id: G8ANT5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1064539:Sp245p RS04960
gene id: 1064539:Sp245p_RS04960
uniprot id: G8AFK8
names: Similarity
messages: Belongs to the oxoprolinase family.

1064539:Sp245p RS31920
gene id: 1064539:Sp245p_RS31920
uniprot id: G8B0B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1064539:Sp245p RS21025
gene id: 1064539:Sp245p_RS21025
uniprot id: G8ATK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1064539:Sp245p RS05895
gene id: 1064539:Sp245p_RS05895
uniprot id: G8ANJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1064539:Sp245p RS10210
gene id: 1064539:Sp245p_RS10210
uniprot id: G8AKR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS07930
gene id: 1064539:Sp245p_RS07930
uniprot id: G8AMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1064539:Sp245p RS21695
gene id: 1064539:Sp245p_RS21695
uniprot id: G8ANV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1064539:Sp245p RS07510
gene id: 1064539:Sp245p_RS07510
uniprot id: G8AMG6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1064539:Sp245p RS04785
gene id: 1064539:Sp245p_RS04785
uniprot id: G8AFP6
names: Similarity
messages: Belongs to the peptidase M24B family.

1064539:Sp245p RS19230
gene id: 1064539:Sp245p_RS19230
uniprot id: G8ASF9
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS16255
gene id: 1064539:Sp245p_RS16255
uniprot id: G8AQF2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1064539:Sp245p RS32505
gene id: 1064539:Sp245p_RS32505
uniprot id: G8B0M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1064539:Sp245p RS11300
gene id: 1064539:Sp245p_RS11300
uniprot id: G8AK05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1064539:Sp245p RS19175
gene id: 1064539:Sp245p_RS19175
uniprot id: G8ASE3
names: Subcellular Location Annotation
messages: Membrane

1064539:Sp245p RS21950
gene id: 1064539:Sp245p_RS21950
uniprot id: G8AP02
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1064539:Sp245p RS09850
gene id: 1064539:Sp245p_RS09850
uniprot id: G8AKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1064539:Sp245p RS13655
gene id: 1064539:Sp245p_RS13655
uniprot id: G8AIG6
names: Similarity
messages: Belongs to the UPF0310 family.

1064539:Sp245p RS24040
gene id: 1064539:Sp245p_RS24040
uniprot id: G8AX71
names: Similarity
messages: Belongs to the RelE toxin family.

1064539:Sp245p RS15710
gene id: 1064539:Sp245p_RS15710
uniprot id: G8AQ19
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1064539:Sp245p RS27625
gene id: 1064539:Sp245p_RS27625
uniprot id: G8AV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS30510
gene id: 1064539:Sp245p_RS30510
uniprot id: G8AUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1064539:Sp245p RS14120
gene id: 1064539:Sp245p_RS14120
uniprot id: G8AI18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1064539:Sp245p RS23105
gene id: 1064539:Sp245p_RS23105
uniprot id: G8AXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1064539:Sp245p RS30285
gene id: 1064539:Sp245p_RS30285
uniprot id: G8AUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane