105559:NWAT RS09390
gene id: 105559:NWAT_RS09390
uniprot id: D8K785
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03680
gene id: 105559:NWAT_RS03680
uniprot id: D8KBU7
names: Similarity
messages: Belongs to the acylphosphatase family.

105559:NWAT RS14115
gene id: 105559:NWAT_RS14115
uniprot id: D8KBK2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

105559:NWAT RS10620
gene id: 105559:NWAT_RS10620
uniprot id: D8K7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

105559:NWAT RS03555
gene id: 105559:NWAT_RS03555
uniprot id: D8KBS5
names: Similarity
messages: Belongs to the GppA/Ppx family.

105559:NWAT RS10635
gene id: 105559:NWAT_RS10635
uniprot id: D8K7X5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

105559:NWAT RS08440
gene id: 105559:NWAT_RS08440
uniprot id: D8K6R3
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS09480
gene id: 105559:NWAT_RS09480
uniprot id: D8K7A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

105559:NWAT RS01535
gene id: 105559:NWAT_RS01535
uniprot id: D8K9J2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

105559:NWAT RS11390
gene id: 105559:NWAT_RS11390
uniprot id: D8K8N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

105559:NWAT RS01395
gene id: 105559:NWAT_RS01395
uniprot id: D8K9G4
names: Similarity
messages: Belongs to the pyruvate kinase family.

105559:NWAT RS06440
gene id: 105559:NWAT_RS06440
uniprot id: D8K5Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

105559:NWAT RS09715
gene id: 105559:NWAT_RS09715
uniprot id: D8K7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

105559:NWAT RS10900
gene id: 105559:NWAT_RS10900
uniprot id: D8K8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

105559:NWAT RS08065
gene id: 105559:NWAT_RS08065
uniprot id: D8K6J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

105559:NWAT RS02745
gene id: 105559:NWAT_RS02745
uniprot id: D8KAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS00465
gene id: 105559:NWAT_RS00465
uniprot id: D8K882
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

105559:NWAT RS09885
gene id: 105559:NWAT_RS09885
uniprot id: D8K7H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS10445
gene id: 105559:NWAT_RS10445
uniprot id: D8K7T6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

105559:NWAT RS10705
gene id: 105559:NWAT_RS10705
uniprot id: D8K7X6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS00585
gene id: 105559:NWAT_RS00585
uniprot id: D8K8A7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

105559:NWAT RS06025
gene id: 105559:NWAT_RS06025
uniprot id: D8K5H5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

105559:NWAT RS02570
gene id: 105559:NWAT_RS02570
uniprot id: D8KAH2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

105559:NWAT RS03775
gene id: 105559:NWAT_RS03775
uniprot id: D8KBW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

105559:NWAT RS03020
gene id: 105559:NWAT_RS03020
uniprot id: D8KB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

105559:NWAT RS02095
gene id: 105559:NWAT_RS02095
uniprot id: D8KA77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

105559:NWAT RS03735
gene id: 105559:NWAT_RS03735
uniprot id: D8KBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

105559:NWAT RS00135
gene id: 105559:NWAT_RS00135
uniprot id: D8K822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

105559:NWAT RS07155
gene id: 105559:NWAT_RS07155
uniprot id: D8K634
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

105559:NWAT RS02340
gene id: 105559:NWAT_RS02340
uniprot id: D8KAC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

105559:NWAT RS01285
gene id: 105559:NWAT_RS01285
uniprot id: D8K921
names: Similarity
messages: Belongs to the GARS family.

105559:NWAT RS01105
gene id: 105559:NWAT_RS01105
uniprot id: D8K8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

105559:NWAT RS03150
gene id: 105559:NWAT_RS03150
uniprot id: D8KB66
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

105559:NWAT RS14345
gene id: 105559:NWAT_RS14345
uniprot id: D8KC22
names: Similarity
messages: Belongs to the universal stress protein A family.

105559:NWAT RS10945
gene id: 105559:NWAT_RS10945
uniprot id: D8K8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

105559:NWAT RS15230
gene id: 105559:NWAT_RS15230
uniprot id: D8K4Q1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12840
gene id: 105559:NWAT_RS12840
uniprot id: D8KA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

105559:NWAT RS06805
gene id: 105559:NWAT_RS06805
uniprot id: D8K5X1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

105559:NWAT RS10515
gene id: 105559:NWAT_RS10515
uniprot id: D8K7V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

105559:NWAT RS04730
gene id: 105559:NWAT_RS04730
uniprot id: D8K4S6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS12805
gene id: 105559:NWAT_RS12805
uniprot id: D8KA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS02575
gene id: 105559:NWAT_RS02575
uniprot id: D8KAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

105559:NWAT RS10010
gene id: 105559:NWAT_RS10010
uniprot id: D8K7K1
names: Similarity
messages: Belongs to the pyruvate kinase family.

105559:NWAT RS14995
gene id: 105559:NWAT_RS14995
uniprot id: D8K4K4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

105559:NWAT RS05645
gene id: 105559:NWAT_RS05645
uniprot id: D8K5A4
names: Similarity
messages: Belongs to the universal stress protein A family.

105559:NWAT RS07400
gene id: 105559:NWAT_RS07400
uniprot id: D8K676
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02985
gene id: 105559:NWAT_RS02985
uniprot id: D8KB32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

105559:NWAT RS06735
gene id: 105559:NWAT_RS06735
uniprot id: D8K5V7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

105559:NWAT RS15115
gene id: 105559:NWAT_RS15115
uniprot id: D8K4M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

105559:NWAT RS01495
gene id: 105559:NWAT_RS01495
uniprot id: D8K9I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

105559:NWAT RS07205
gene id: 105559:NWAT_RS07205
uniprot id: D8K644
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

105559:NWAT RS10545
gene id: 105559:NWAT_RS10545
uniprot id: D8K7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

105559:NWAT RS10660
gene id: 105559:NWAT_RS10660
uniprot id: D8K7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

105559:NWAT RS10745
gene id: 105559:NWAT_RS10745
uniprot id: D8K7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

105559:NWAT RS10355
gene id: 105559:NWAT_RS10355
uniprot id: D8K7R8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

105559:NWAT RS05320
gene id: 105559:NWAT_RS05320
uniprot id: D8K541
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

105559:NWAT RS05865
gene id: 105559:NWAT_RS05865
uniprot id: D8K5E7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

105559:NWAT RS00195
gene id: 105559:NWAT_RS00195
uniprot id: D8K834
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

105559:NWAT RS12505
gene id: 105559:NWAT_RS12505
uniprot id: D8K9Z0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

105559:NWAT RS08200
gene id: 105559:NWAT_RS08200
uniprot id: D8K6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

105559:NWAT RS13325
gene id: 105559:NWAT_RS13325
uniprot id: D8KAS9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

105559:NWAT RS03540
gene id: 105559:NWAT_RS03540
uniprot id: D8KBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS11020
gene id: 105559:NWAT_RS11020
uniprot id: D8K8F4
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

105559:NWAT RS11725
gene id: 105559:NWAT_RS11725
uniprot id: D8K971
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS12055
gene id: 105559:NWAT_RS12055
uniprot id: D8K9C6
names: Similarity
messages: Belongs to the catalase family.

105559:NWAT RS00650
gene id: 105559:NWAT_RS00650
uniprot id: D8K8Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS03190
gene id: 105559:NWAT_RS03190
uniprot id: D8KB74
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

105559:NWAT RS09550
gene id: 105559:NWAT_RS09550
uniprot id: D8K7B4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

105559:NWAT RS02765
gene id: 105559:NWAT_RS02765
uniprot id: D8KAY9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

105559:NWAT RS07255
gene id: 105559:NWAT_RS07255
uniprot id: D8K654
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

105559:NWAT RS00930
gene id: 105559:NWAT_RS00930
uniprot id: D8K8V6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

105559:NWAT RS00615
gene id: 105559:NWAT_RS00615
uniprot id: D8K8P8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

105559:NWAT RS04460
gene id: 105559:NWAT_RS04460
uniprot id: D8K4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS13955
gene id: 105559:NWAT_RS13955
uniprot id: D8KBH2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

105559:NWAT RS11015
gene id: 105559:NWAT_RS11015
uniprot id: D8K8F3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

105559:NWAT RS02180
gene id: 105559:NWAT_RS02180
uniprot id: D8KA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

105559:NWAT RS03675
gene id: 105559:NWAT_RS03675
uniprot id: D8KBU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

105559:NWAT RS03310
gene id: 105559:NWAT_RS03310
uniprot id: D8KBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

105559:NWAT RS08290
gene id: 105559:NWAT_RS08290
uniprot id: D8K6P2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

105559:NWAT RS11070
gene id: 105559:NWAT_RS11070
uniprot id: D8K8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

105559:NWAT RS14795
gene id: 105559:NWAT_RS14795
uniprot id: D8KCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS08965
gene id: 105559:NWAT_RS08965
uniprot id: D8K709
names: Similarity
messages: Belongs to the RecJ family.

105559:NWAT RS04775
gene id: 105559:NWAT_RS04775
uniprot id: D8K4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

105559:NWAT RS08940
gene id: 105559:NWAT_RS08940
uniprot id: D8K703
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS11250
gene id: 105559:NWAT_RS11250
uniprot id: D8K8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

105559:NWAT RS03365
gene id: 105559:NWAT_RS03365
uniprot id: D8KBN2
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS01520
gene id: 105559:NWAT_RS01520
uniprot id: D8K9I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS08995
gene id: 105559:NWAT_RS08995
uniprot id: D8K715
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

105559:NWAT RS04100
gene id: 105559:NWAT_RS04100
uniprot id: D8K486
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

105559:NWAT RS06815
gene id: 105559:NWAT_RS06815
uniprot id: D8K5X3
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

105559:NWAT RS01355
gene id: 105559:NWAT_RS01355
uniprot id: D8K9F6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

105559:NWAT RS15005
gene id: 105559:NWAT_RS15005
uniprot id: D8K4K6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

105559:NWAT RS10550
gene id: 105559:NWAT_RS10550
uniprot id: D8K7V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

105559:NWAT RS01055
gene id: 105559:NWAT_RS01055
uniprot id: D8K8X7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04950
gene id: 105559:NWAT_RS04950
uniprot id: D8K4W9
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

105559:NWAT RS05735
gene id: 105559:NWAT_RS05735
uniprot id: D8K5C2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS03530
gene id: 105559:NWAT_RS03530
uniprot id: D8KBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

105559:NWAT RS00220
gene id: 105559:NWAT_RS00220
uniprot id: D8K839
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

105559:NWAT RS05980
gene id: 105559:NWAT_RS05980
uniprot id: D8K5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

105559:NWAT RS07760
gene id: 105559:NWAT_RS07760
uniprot id: D8K6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

105559:NWAT RS05585
gene id: 105559:NWAT_RS05585
uniprot id: D8K591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS01680
gene id: 105559:NWAT_RS01680
uniprot id: D8K9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

105559:NWAT RS07655
gene id: 105559:NWAT_RS07655
uniprot id: D8K6C4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

105559:NWAT RS11195
gene id: 105559:NWAT_RS11195
uniprot id: D8K8J1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

105559:NWAT RS04115
gene id: 105559:NWAT_RS04115
uniprot id: D8K488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

105559:NWAT RS07215
gene id: 105559:NWAT_RS07215
uniprot id: D8K646
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

105559:NWAT RS12735
gene id: 105559:NWAT_RS12735
uniprot id: D8KA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

105559:NWAT RS01420
gene id: 105559:NWAT_RS01420
uniprot id: D8K9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

105559:NWAT RS01005
gene id: 105559:NWAT_RS01005
uniprot id: D8K8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

105559:NWAT RS02160
gene id: 105559:NWAT_RS02160
uniprot id: D8KA89
names: Similarity
messages: Belongs to the UPF0434 family.

105559:NWAT RS04880
gene id: 105559:NWAT_RS04880
uniprot id: D8K4V5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

105559:NWAT RS15200
gene id: 105559:NWAT_RS15200
uniprot id: D8K4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

105559:NWAT RS12220
gene id: 105559:NWAT_RS12220
uniprot id: D8K9U3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

105559:NWAT RS03755
gene id: 105559:NWAT_RS03755
uniprot id: D8KBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

105559:NWAT RS09890
gene id: 105559:NWAT_RS09890
uniprot id: D8K7H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

105559:NWAT RS02515
gene id: 105559:NWAT_RS02515
uniprot id: D8KAG2
names: Subunit
messages: Homotetramer.

105559:NWAT RS05140
gene id: 105559:NWAT_RS05140
uniprot id: D8K507
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

105559:NWAT RS01725
gene id: 105559:NWAT_RS01725
uniprot id: D8K9N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS08725
gene id: 105559:NWAT_RS08725
uniprot id: D8K6W8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12610
gene id: 105559:NWAT_RS12610
uniprot id: D8KA08
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

105559:NWAT RS12825
gene id: 105559:NWAT_RS12825
uniprot id: D8KA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS03265
gene id: 105559:NWAT_RS03265
uniprot id: D8KB89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

105559:NWAT RS10200
gene id: 105559:NWAT_RS10200
uniprot id: D8K7N7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS10790
gene id: 105559:NWAT_RS10790
uniprot id: D8K801
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

105559:NWAT RS06105
gene id: 105559:NWAT_RS06105
uniprot id: D8K5J1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS06955
gene id: 105559:NWAT_RS06955
uniprot id: D8K5Z7
names: Similarity
messages: Belongs to the YkuD family.

105559:NWAT RS09850
gene id: 105559:NWAT_RS09850
uniprot id: D8K7G9
names: Similarity
messages: Belongs to the TrpF family.

105559:NWAT RS01800
gene id: 105559:NWAT_RS01800
uniprot id: D8K9P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS14800
gene id: 105559:NWAT_RS14800
uniprot id: D8KCA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

105559:NWAT RS16985
gene id: 105559:NWAT_RS16985
uniprot id: D8K5X4
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the IS1 elements InsA family.

105559:NWAT RS01515
gene id: 105559:NWAT_RS01515
uniprot id: D8K9I8
names: Similarity
messages: Belongs to the BolA/IbaG family.

105559:NWAT RS09805
gene id: 105559:NWAT_RS09805
uniprot id: D8K7G0
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

105559:NWAT RS05235
gene id: 105559:NWAT_RS05235
uniprot id: D8K524
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

105559:NWAT RS02600
gene id: 105559:NWAT_RS02600
uniprot id: D8KAH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS07535
gene id: 105559:NWAT_RS07535
uniprot id: D8K6A1
names: Similarity
messages: Belongs to the glutamate synthase family.

105559:NWAT RS02465
gene id: 105559:NWAT_RS02465
uniprot id: D8KAF2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

105559:NWAT RS04940
gene id: 105559:NWAT_RS04940
uniprot id: D8K4W7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03395
gene id: 105559:NWAT_RS03395
uniprot id: D8KBN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

105559:NWAT RS12995
gene id: 105559:NWAT_RS12995
uniprot id: D8KAL2
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

105559:NWAT RS15380
gene id: 105559:NWAT_RS15380
uniprot id: D8KCE2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

105559:NWAT RS01295
gene id: 105559:NWAT_RS01295
uniprot id: D8K923
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

105559:NWAT RS10075
gene id: 105559:NWAT_RS10075
uniprot id: D8K7L4
names: Similarity
messages: Belongs to the MlaA family.

105559:NWAT RS05360
gene id: 105559:NWAT_RS05360
uniprot id: D8K545
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

105559:NWAT RS03725
gene id: 105559:NWAT_RS03725
uniprot id: D8KBV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS04220
gene id: 105559:NWAT_RS04220
uniprot id: D8K4A7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

105559:NWAT RS11160
gene id: 105559:NWAT_RS11160
uniprot id: D8K8I3
names: Similarity
messages: Belongs to the MotB family.

105559:NWAT RS00895
gene id: 105559:NWAT_RS00895
uniprot id: D8K8V1
names: Similarity
messages: Belongs to the WrbA family.

105559:NWAT RS05155
gene id: 105559:NWAT_RS05155
uniprot id: D8K510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

105559:NWAT RS04540
gene id: 105559:NWAT_RS04540
uniprot id: D8K4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

105559:NWAT RS12590
gene id: 105559:NWAT_RS12590
uniprot id: D8KA04
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

105559:NWAT RS10965
gene id: 105559:NWAT_RS10965
uniprot id: D8K8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

105559:NWAT RS08955
gene id: 105559:NWAT_RS08955
uniprot id: D8K707
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

105559:NWAT RS10610
gene id: 105559:NWAT_RS10610
uniprot id: D8K7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

105559:NWAT RS10735
gene id: 105559:NWAT_RS10735
uniprot id: D8K7Z0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

105559:NWAT RS05630
gene id: 105559:NWAT_RS05630
uniprot id: D8K5A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

105559:NWAT RS10415
gene id: 105559:NWAT_RS10415
uniprot id: D8K7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS13405
gene id: 105559:NWAT_RS13405
uniprot id: D8KAU6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

105559:NWAT RS02240
gene id: 105559:NWAT_RS02240
uniprot id: D8KAA5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

105559:NWAT RS02470
gene id: 105559:NWAT_RS02470
uniprot id: D8KAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

105559:NWAT RS02555
gene id: 105559:NWAT_RS02555
uniprot id: D8KAG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

105559:NWAT RS04245
gene id: 105559:NWAT_RS04245
uniprot id: D8K4B2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

105559:NWAT RS05760
gene id: 105559:NWAT_RS05760
uniprot id: D8K5C7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03160
gene id: 105559:NWAT_RS03160
uniprot id: D8KB68
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

105559:NWAT RS14590
gene id: 105559:NWAT_RS14590
uniprot id: D8KC65
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS11260
gene id: 105559:NWAT_RS11260
uniprot id: D8K8K4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10380
gene id: 105559:NWAT_RS10380
uniprot id: D8K7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

105559:NWAT RS10375
gene id: 105559:NWAT_RS10375
uniprot id: D8K7S2
names: Similarity
messages: Belongs to the UPF0166 family.

105559:NWAT RS13350
gene id: 105559:NWAT_RS13350
uniprot id: D8KAT4
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03255
gene id: 105559:NWAT_RS03255
uniprot id: D8KB87
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

105559:NWAT RS07315
gene id: 105559:NWAT_RS07315
uniprot id: D8K665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

105559:NWAT RS01530
gene id: 105559:NWAT_RS01530
uniprot id: D8K9J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

105559:NWAT RS04545
gene id: 105559:NWAT_RS04545
uniprot id: D8K4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

105559:NWAT RS07700
gene id: 105559:NWAT_RS07700
uniprot id: D8K6D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

105559:NWAT RS01090
gene id: 105559:NWAT_RS01090
uniprot id: D8K8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS06765
gene id: 105559:NWAT_RS06765
uniprot id: D8K5W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

105559:NWAT RS05730
gene id: 105559:NWAT_RS05730
uniprot id: D8K5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

105559:NWAT RS11780
gene id: 105559:NWAT_RS11780
uniprot id: D8K982
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

105559:NWAT RS01335
gene id: 105559:NWAT_RS01335
uniprot id: D8K9F2
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02785
gene id: 105559:NWAT_RS02785
uniprot id: D8KAZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS06425
gene id: 105559:NWAT_RS06425
uniprot id: D8K5Q2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS13695
gene id: 105559:NWAT_RS13695
uniprot id: D8KBC7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

105559:NWAT RS01155
gene id: 105559:NWAT_RS01155
uniprot id: D8K8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

105559:NWAT RS08925
gene id: 105559:NWAT_RS08925
uniprot id: D8K700
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

105559:NWAT RS11185
gene id: 105559:NWAT_RS11185
uniprot id: D8K8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

105559:NWAT RS08270
gene id: 105559:NWAT_RS08270
uniprot id: D8K6N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02320
gene id: 105559:NWAT_RS02320
uniprot id: D8KAC2
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07055
gene id: 105559:NWAT_RS07055
uniprot id: D8K616
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02875
gene id: 105559:NWAT_RS02875
uniprot id: D8KB11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

105559:NWAT RS05900
gene id: 105559:NWAT_RS05900
uniprot id: D8K5F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

105559:NWAT RS04765
gene id: 105559:NWAT_RS04765
uniprot id: D8K4T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

105559:NWAT RS05685
gene id: 105559:NWAT_RS05685
uniprot id: D8K5B2
names: Similarity
messages: Belongs to the TPP enzyme family.

105559:NWAT RS11200
gene id: 105559:NWAT_RS11200
uniprot id: D8K8J2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

105559:NWAT RS05315
gene id: 105559:NWAT_RS05315
uniprot id: D8K540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

105559:NWAT RS00855
gene id: 105559:NWAT_RS00855
uniprot id: D8K8U3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

105559:NWAT RS08260
gene id: 105559:NWAT_RS08260
uniprot id: D8K6N6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

105559:NWAT RS03600
gene id: 105559:NWAT_RS03600
uniprot id: D8KBT4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

105559:NWAT RS05775
gene id: 105559:NWAT_RS05775
uniprot id: D8K5D0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

105559:NWAT RS01545
gene id: 105559:NWAT_RS01545
uniprot id: D8K9J4
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS06585
gene id: 105559:NWAT_RS06585
uniprot id: D8K5T2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

105559:NWAT RS01020
gene id: 105559:NWAT_RS01020
uniprot id: D8K8X1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

105559:NWAT RS10500
gene id: 105559:NWAT_RS10500
uniprot id: D8K7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

105559:NWAT RS14365
gene id: 105559:NWAT_RS14365
uniprot id: D8KC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

105559:NWAT RS02565
gene id: 105559:NWAT_RS02565
uniprot id: D8KAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

105559:NWAT RS03475
gene id: 105559:NWAT_RS03475
uniprot id: D8KBQ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

105559:NWAT RS07195
gene id: 105559:NWAT_RS07195
uniprot id: D8K642
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

105559:NWAT RS00670
gene id: 105559:NWAT_RS00670
uniprot id: D8K8Q8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS12175
gene id: 105559:NWAT_RS12175
uniprot id: D8K9T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS14490
gene id: 105559:NWAT_RS14490
uniprot id: D8KC48
names: Similarity
messages: Belongs to the SCO1/2 family.

105559:NWAT RS13545
gene id: 105559:NWAT_RS13545
uniprot id: D8KB99
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

105559:NWAT RS09650
gene id: 105559:NWAT_RS09650
uniprot id: D8K7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

105559:NWAT RS07965
gene id: 105559:NWAT_RS07965
uniprot id: D8K6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

105559:NWAT RS15090
gene id: 105559:NWAT_RS15090
uniprot id: D8K4M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS04150
gene id: 105559:NWAT_RS04150
uniprot id: D8K493
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10225
gene id: 105559:NWAT_RS10225
uniprot id: D8K7P2
names: Similarity
messages: Belongs to the UPF0234 family.

105559:NWAT RS12605
gene id: 105559:NWAT_RS12605
uniprot id: D8KA07
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

105559:NWAT RS02750
gene id: 105559:NWAT_RS02750
uniprot id: D8KAY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS11085
gene id: 105559:NWAT_RS11085
uniprot id: D8K8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

105559:NWAT RS00075
gene id: 105559:NWAT_RS00075
uniprot id: D8K810
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

105559:NWAT RS13475
gene id: 105559:NWAT_RS13475
uniprot id: D8KAW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

105559:NWAT RS09370
gene id: 105559:NWAT_RS09370
uniprot id: D8K781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS14265
gene id: 105559:NWAT_RS14265
uniprot id: D8KC06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

105559:NWAT RS01190
gene id: 105559:NWAT_RS01190
uniprot id: D8K904
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

105559:NWAT RS02195
gene id: 105559:NWAT_RS02195
uniprot id: D8KA96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

105559:NWAT RS12390
gene id: 105559:NWAT_RS12390
uniprot id: D8K9X2
names: Similarity
messages: Belongs to the RelE toxin family.

105559:NWAT RS06285
gene id: 105559:NWAT_RS06285
uniprot id: D8K5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

105559:NWAT RS04830
gene id: 105559:NWAT_RS04830
uniprot id: D8K4U6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

105559:NWAT RS03760
gene id: 105559:NWAT_RS03760
uniprot id: D8KBW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

105559:NWAT RS04800
gene id: 105559:NWAT_RS04800
uniprot id: D8K4T9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

105559:NWAT RS12135
gene id: 105559:NWAT_RS12135
uniprot id: D8K9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

105559:NWAT RS15010
gene id: 105559:NWAT_RS15010
uniprot id: D8K4K7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02620
gene id: 105559:NWAT_RS02620
uniprot id: D8KAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

105559:NWAT RS15590
gene id: 105559:NWAT_RS15590
uniprot id: D8K4X5
names: Similarity
messages: Belongs to the peptidase S8 family.

105559:NWAT RS10115
gene id: 105559:NWAT_RS10115
uniprot id: D8K7M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

105559:NWAT RS03665
gene id: 105559:NWAT_RS03665
uniprot id: D8KBU4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

105559:NWAT RS00675
gene id: 105559:NWAT_RS00675
uniprot id: D8K8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

105559:NWAT RS03900
gene id: 105559:NWAT_RS03900
uniprot id: D8KBY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

105559:NWAT RS04410
gene id: 105559:NWAT_RS04410
uniprot id: D8K4E3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

105559:NWAT RS13370
gene id: 105559:NWAT_RS13370
uniprot id: D8KAT8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

105559:NWAT RS05110
gene id: 105559:NWAT_RS05110
uniprot id: D8K502
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS13465
gene id: 105559:NWAT_RS13465
uniprot id: D8KAV8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

105559:NWAT RS13730
gene id: 105559:NWAT_RS13730
uniprot id: D8KBD3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

105559:NWAT RS02400
gene id: 105559:NWAT_RS02400
uniprot id: D8KAD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

105559:NWAT RS15095
gene id: 105559:NWAT_RS15095
uniprot id: D8K4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

105559:NWAT RS07175
gene id: 105559:NWAT_RS07175
uniprot id: D8K638
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

105559:NWAT RS06170
gene id: 105559:NWAT_RS06170
uniprot id: D8K5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

105559:NWAT RS03385
gene id: 105559:NWAT_RS03385
uniprot id: D8KBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

105559:NWAT RS01125
gene id: 105559:NWAT_RS01125
uniprot id: D8K8Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

105559:NWAT RS09985
gene id: 105559:NWAT_RS09985
uniprot id: D8K7J6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

105559:NWAT RS02185
gene id: 105559:NWAT_RS02185
uniprot id: D8KA94
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS05295
gene id: 105559:NWAT_RS05295
uniprot id: D8K536
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

105559:NWAT RS10270
gene id: 105559:NWAT_RS10270
uniprot id: D8K7Q1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS00975
gene id: 105559:NWAT_RS00975
uniprot id: D8K8W2
names: Similarity
messages: Belongs to the HsdR family.

105559:NWAT RS04560
gene id: 105559:NWAT_RS04560
uniprot id: D8K4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

105559:NWAT RS11925
gene id: 105559:NWAT_RS11925
uniprot id: D8K9A7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

105559:NWAT RS06995
gene id: 105559:NWAT_RS06995
uniprot id: D8K604
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

105559:NWAT RS10535
gene id: 105559:NWAT_RS10535
uniprot id: D8K7V5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

105559:NWAT RS00295
gene id: 105559:NWAT_RS00295
uniprot id: D8K851
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02870
gene id: 105559:NWAT_RS02870
uniprot id: D8KB10
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

105559:NWAT RS15075
gene id: 105559:NWAT_RS15075
uniprot id: D8K4M1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

105559:NWAT RS07595
gene id: 105559:NWAT_RS07595
uniprot id: D8K6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS04590
gene id: 105559:NWAT_RS04590
uniprot id: D8K4H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

105559:NWAT RS10120
gene id: 105559:NWAT_RS10120
uniprot id: D8K7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS08385
gene id: 105559:NWAT_RS08385
uniprot id: D8K6Q2
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS15625
gene id: 105559:NWAT_RS15625
uniprot id: D8K5Q3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

105559:NWAT RS12560
gene id: 105559:NWAT_RS12560
uniprot id: D8K9Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

105559:NWAT RS07325
gene id: 105559:NWAT_RS07325
uniprot id: D8K666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

105559:NWAT RS12355
gene id: 105559:NWAT_RS12355
uniprot id: D8K9W5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07225
gene id: 105559:NWAT_RS07225
uniprot id: D8K648
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10835
gene id: 105559:NWAT_RS10835
uniprot id: D8K8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

105559:NWAT RS00480
gene id: 105559:NWAT_RS00480
uniprot id: D8K886
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04445
gene id: 105559:NWAT_RS04445
uniprot id: D8K4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS02285
gene id: 105559:NWAT_RS02285
uniprot id: D8KAB5
names: Similarity
messages: Belongs to the glutamine synthetase family.

105559:NWAT RS02680
gene id: 105559:NWAT_RS02680
uniprot id: D8KAX2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

105559:NWAT RS00470
gene id: 105559:NWAT_RS00470
uniprot id: D8K883
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12615
gene id: 105559:NWAT_RS12615
uniprot id: D8KA09
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

105559:NWAT RS15170
gene id: 105559:NWAT_RS15170
uniprot id: D8K4N9
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

105559:NWAT RS04770
gene id: 105559:NWAT_RS04770
uniprot id: D8K4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

105559:NWAT RS09200
gene id: 105559:NWAT_RS09200
uniprot id: D8K752
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

105559:NWAT RS08500
gene id: 105559:NWAT_RS08500
uniprot id: D8K6S5
names: Similarity
messages: Belongs to the peptidase M16 family.

105559:NWAT RS03225
gene id: 105559:NWAT_RS03225
uniprot id: D8KB81
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

105559:NWAT RS04740
gene id: 105559:NWAT_RS04740
uniprot id: D8K4S8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

105559:NWAT RS00955
gene id: 105559:NWAT_RS00955
uniprot id: D8K8V8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS02820
gene id: 105559:NWAT_RS02820
uniprot id: D8KB00
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

105559:NWAT RS01645
gene id: 105559:NWAT_RS01645
uniprot id: D8K9L4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

105559:NWAT RS11095
gene id: 105559:NWAT_RS11095
uniprot id: D8K8H0
names: Subcellular Location Annotation
messages: Cytoplasm

105559:NWAT RS02460
gene id: 105559:NWAT_RS02460
uniprot id: D8KAF1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

105559:NWAT RS13220
gene id: 105559:NWAT_RS13220
uniprot id: D8KAQ8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

105559:NWAT RS05410
gene id: 105559:NWAT_RS05410
uniprot id: D8K555
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

105559:NWAT RS08915
gene id: 105559:NWAT_RS08915
uniprot id: D8K6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

105559:NWAT RS01785
gene id: 105559:NWAT_RS01785
uniprot id: D8K9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

105559:NWAT RS15110
gene id: 105559:NWAT_RS15110
uniprot id: D8K4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

105559:NWAT RS05700
gene id: 105559:NWAT_RS05700
uniprot id: D8K5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

105559:NWAT RS14130
gene id: 105559:NWAT_RS14130
uniprot id: D8KBK5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

105559:NWAT RS02725
gene id: 105559:NWAT_RS02725
uniprot id: D8KAY2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

105559:NWAT RS00830
gene id: 105559:NWAT_RS00830
uniprot id: D8K8T8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

105559:NWAT RS03550
gene id: 105559:NWAT_RS03550
uniprot id: D8KBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

105559:NWAT RS10250
gene id: 105559:NWAT_RS10250
uniprot id: D8K7P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

105559:NWAT RS01850
gene id: 105559:NWAT_RS01850
uniprot id: D8K9Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

105559:NWAT RS08295
gene id: 105559:NWAT_RS08295
uniprot id: D8K6P3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

105559:NWAT RS11245
gene id: 105559:NWAT_RS11245
uniprot id: D8K8K1
names: Similarity
messages: Belongs to the skp family.

105559:NWAT RS09665
gene id: 105559:NWAT_RS09665
uniprot id: D8K7D3
names: Similarity
messages: Belongs to the CutA family.

105559:NWAT RS02410
gene id: 105559:NWAT_RS02410
uniprot id: D8KAE0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

105559:NWAT RS11300
gene id: 105559:NWAT_RS11300
uniprot id: D8K8L2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

105559:NWAT RS12165
gene id: 105559:NWAT_RS12165
uniprot id: D8K9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

105559:NWAT RS10970
gene id: 105559:NWAT_RS10970
uniprot id: D8K8E4
names: Similarity
messages: Belongs to the YciI family.

105559:NWAT RS13970
gene id: 105559:NWAT_RS13970
uniprot id: D8KBH5
names: Similarity
messages: Belongs to the YoeB family.

105559:NWAT RS11520
gene id: 105559:NWAT_RS11520
uniprot id: D8K932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

105559:NWAT RS08490
gene id: 105559:NWAT_RS08490
uniprot id: D8K6S3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

105559:NWAT RS01210
gene id: 105559:NWAT_RS01210
uniprot id: D8K908
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

105559:NWAT RS02445
gene id: 105559:NWAT_RS02445
uniprot id: D8KAE7
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

105559:NWAT RS02860
gene id: 105559:NWAT_RS02860
uniprot id: D8KB08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

105559:NWAT RS09030
gene id: 105559:NWAT_RS09030
uniprot id: D8K722
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10890
gene id: 105559:NWAT_RS10890
uniprot id: D8K8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

105559:NWAT RS01965
gene id: 105559:NWAT_RS01965
uniprot id: D8K9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS09285
gene id: 105559:NWAT_RS09285
uniprot id: D8K766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS01390
gene id: 105559:NWAT_RS01390
uniprot id: D8K9G3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS06320
gene id: 105559:NWAT_RS06320
uniprot id: D8K5N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

105559:NWAT RS07570
gene id: 105559:NWAT_RS07570
uniprot id: D8K6A8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10410
gene id: 105559:NWAT_RS10410
uniprot id: D8K7S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

105559:NWAT RS02730
gene id: 105559:NWAT_RS02730
uniprot id: D8KAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

105559:NWAT RS03195
gene id: 105559:NWAT_RS03195
uniprot id: D8KB75
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12530
gene id: 105559:NWAT_RS12530
uniprot id: D8K9Z5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

105559:NWAT RS03990
gene id: 105559:NWAT_RS03990
uniprot id: D8K466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS11860
gene id: 105559:NWAT_RS11860
uniprot id: D8K995
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS14450
gene id: 105559:NWAT_RS14450
uniprot id: D8KC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS03120
gene id: 105559:NWAT_RS03120
uniprot id: D8KB60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS06885
gene id: 105559:NWAT_RS06885
uniprot id: D8K5Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

105559:NWAT RS07250
gene id: 105559:NWAT_RS07250
uniprot id: D8K653
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

105559:NWAT RS10560
gene id: 105559:NWAT_RS10560
uniprot id: D8K7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

105559:NWAT RS07415
gene id: 105559:NWAT_RS07415
uniprot id: D8K679
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

105559:NWAT RS08250
gene id: 105559:NWAT_RS08250
uniprot id: D8K6N4
names: Similarity
messages: Belongs to the peptidase S1C family.

105559:NWAT RS11745
gene id: 105559:NWAT_RS11745
uniprot id: D8K975
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

105559:NWAT RS10615
gene id: 105559:NWAT_RS10615
uniprot id: D8K7X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

105559:NWAT RS02615
gene id: 105559:NWAT_RS02615
uniprot id: D8KAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

105559:NWAT RS06625
gene id: 105559:NWAT_RS06625
uniprot id: D8K5T6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10650
gene id: 105559:NWAT_RS10650
uniprot id: D8K7W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

105559:NWAT RS08825
gene id: 105559:NWAT_RS08825
uniprot id: D8K6Y3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

105559:NWAT RS01640
gene id: 105559:NWAT_RS01640
uniprot id: D8K9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS05115
gene id: 105559:NWAT_RS05115
uniprot id: D8K503
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

105559:NWAT RS09670
gene id: 105559:NWAT_RS09670
uniprot id: D8K7D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

105559:NWAT RS09000
gene id: 105559:NWAT_RS09000
uniprot id: D8K716
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS00815
gene id: 105559:NWAT_RS00815
uniprot id: D8K8T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS03135
gene id: 105559:NWAT_RS03135
uniprot id: D8KB63
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

105559:NWAT RS03465
gene id: 105559:NWAT_RS03465
uniprot id: D8KBQ5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

105559:NWAT RS13305
gene id: 105559:NWAT_RS13305
uniprot id: D8KAS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

105559:NWAT RS02330
gene id: 105559:NWAT_RS02330
uniprot id: D8KAC4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

105559:NWAT RS05580
gene id: 105559:NWAT_RS05580
uniprot id: D8K590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

105559:NWAT RS14080
gene id: 105559:NWAT_RS14080
uniprot id: D8KBJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

105559:NWAT RS06630
gene id: 105559:NWAT_RS06630
uniprot id: D8K5T7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

105559:NWAT RS03405
gene id: 105559:NWAT_RS03405
uniprot id: D8KBP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

105559:NWAT RS14075
gene id: 105559:NWAT_RS14075
uniprot id: D8KBJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

105559:NWAT RS03080
gene id: 105559:NWAT_RS03080
uniprot id: D8KB52
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

105559:NWAT RS00080
gene id: 105559:NWAT_RS00080
uniprot id: D8K811
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

105559:NWAT RS00405
gene id: 105559:NWAT_RS00405
uniprot id: D8K870
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

105559:NWAT RS07040
gene id: 105559:NWAT_RS07040
uniprot id: D8K613
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

105559:NWAT RS00795
gene id: 105559:NWAT_RS00795
uniprot id: D8K8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS08435
gene id: 105559:NWAT_RS08435
uniprot id: D8K6R2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

105559:NWAT RS11760
gene id: 105559:NWAT_RS11760
uniprot id: D8K978
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

105559:NWAT RS06295
gene id: 105559:NWAT_RS06295
uniprot id: D8K5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

105559:NWAT RS09680
gene id: 105559:NWAT_RS09680
uniprot id: D8K7D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

105559:NWAT RS09815
gene id: 105559:NWAT_RS09815
uniprot id: D8K7G2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10150
gene id: 105559:NWAT_RS10150
uniprot id: D8K7M9
names: Similarity
messages: Belongs to the histone deacetylase family.

105559:NWAT RS10755
gene id: 105559:NWAT_RS10755
uniprot id: D8K7Z4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

105559:NWAT RS07045
gene id: 105559:NWAT_RS07045
uniprot id: D8K614
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

105559:NWAT RS11970
gene id: 105559:NWAT_RS11970
uniprot id: D8K9B3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

105559:NWAT RS03415
gene id: 105559:NWAT_RS03415
uniprot id: D8KBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

105559:NWAT RS10930
gene id: 105559:NWAT_RS10930
uniprot id: D8K8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

105559:NWAT RS11275
gene id: 105559:NWAT_RS11275
uniprot id: D8K8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

105559:NWAT RS12200
gene id: 105559:NWAT_RS12200
uniprot id: D8K9T9
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12645
gene id: 105559:NWAT_RS12645
uniprot id: D8KA14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

105559:NWAT RS12850
gene id: 105559:NWAT_RS12850
uniprot id: D8KA51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

105559:NWAT RS09910
gene id: 105559:NWAT_RS09910
uniprot id: D8K7I1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS09160
gene id: 105559:NWAT_RS09160
uniprot id: D8K745
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

105559:NWAT RS12800
gene id: 105559:NWAT_RS12800
uniprot id: D8KA41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS12920
gene id: 105559:NWAT_RS12920
uniprot id: D8KAJ7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03905
gene id: 105559:NWAT_RS03905
uniprot id: D8KBY6
names: Similarity
messages: Belongs to the aspartokinase family.

105559:NWAT RS03965
gene id: 105559:NWAT_RS03965
uniprot id: D8K461
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

105559:NWAT RS10665
gene id: 105559:NWAT_RS10665
uniprot id: D8K7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

105559:NWAT RS09050
gene id: 105559:NWAT_RS09050
uniprot id: D8K725
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS00820
gene id: 105559:NWAT_RS00820
uniprot id: D8K8T6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

105559:NWAT RS00875
gene id: 105559:NWAT_RS00875
uniprot id: D8K8U7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

105559:NWAT RS06745
gene id: 105559:NWAT_RS06745
uniprot id: D8K5V9
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS13810
gene id: 105559:NWAT_RS13810
uniprot id: D8KBE5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS06415
gene id: 105559:NWAT_RS06415
uniprot id: D8K5Q0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

105559:NWAT RS11280
gene id: 105559:NWAT_RS11280
uniprot id: D8K8K8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10570
gene id: 105559:NWAT_RS10570
uniprot id: D8K7W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

105559:NWAT RS01120
gene id: 105559:NWAT_RS01120
uniprot id: D8K8Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

105559:NWAT RS15105
gene id: 105559:NWAT_RS15105
uniprot id: D8K4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

105559:NWAT RS14950
gene id: 105559:NWAT_RS14950
uniprot id: D8K4J6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS01480
gene id: 105559:NWAT_RS01480
uniprot id: D8K9I1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

105559:NWAT RS07050
gene id: 105559:NWAT_RS07050
uniprot id: D8K615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

105559:NWAT RS08990
gene id: 105559:NWAT_RS08990
uniprot id: D8K714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

105559:NWAT RS07280
gene id: 105559:NWAT_RS07280
uniprot id: D8K658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

105559:NWAT RS05625
gene id: 105559:NWAT_RS05625
uniprot id: D8K599
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

105559:NWAT RS02965
gene id: 105559:NWAT_RS02965
uniprot id: D8KB27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

105559:NWAT RS12830
gene id: 105559:NWAT_RS12830
uniprot id: D8KA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS05370
gene id: 105559:NWAT_RS05370
uniprot id: D8K547
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

105559:NWAT RS06760
gene id: 105559:NWAT_RS06760
uniprot id: D8K5W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

105559:NWAT RS02580
gene id: 105559:NWAT_RS02580
uniprot id: D8KAH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

105559:NWAT RS11440
gene id: 105559:NWAT_RS11440
uniprot id: D8K8P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

105559:NWAT RS10295
gene id: 105559:NWAT_RS10295
uniprot id: D8K7Q6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

105559:NWAT RS14890
gene id: 105559:NWAT_RS14890
uniprot id: D8KCB6
names: Similarity
messages: Belongs to the Smg family.

105559:NWAT RS14750
gene id: 105559:NWAT_RS14750
uniprot id: D8KC94
names: Similarity
messages: Belongs to the transglycosylase Slt family.

105559:NWAT RS15040
gene id: 105559:NWAT_RS15040
uniprot id: D8K4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

105559:NWAT RS02995
gene id: 105559:NWAT_RS02995
uniprot id: D8KB34
names: Similarity
messages: Belongs to the SAICAR synthetase family.

105559:NWAT RS10475
gene id: 105559:NWAT_RS10475
uniprot id: D8K7U2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

105559:NWAT RS02790
gene id: 105559:NWAT_RS02790
uniprot id: D8KAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS11055
gene id: 105559:NWAT_RS11055
uniprot id: D8K8G2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

105559:NWAT RS14990
gene id: 105559:NWAT_RS14990
uniprot id: D8K4K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS08800
gene id: 105559:NWAT_RS08800
uniprot id: D8K6X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

105559:NWAT RS05765
gene id: 105559:NWAT_RS05765
uniprot id: D8K5C8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07560
gene id: 105559:NWAT_RS07560
uniprot id: D8K6A6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

105559:NWAT RS01060
gene id: 105559:NWAT_RS01060
uniprot id: D8K8X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

105559:NWAT RS10690
gene id: 105559:NWAT_RS10690
uniprot id: D8K7X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

105559:NWAT RS10555
gene id: 105559:NWAT_RS10555
uniprot id: D8K7V9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

105559:NWAT RS00905
gene id: 105559:NWAT_RS00905
uniprot id: D8K8V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS01425
gene id: 105559:NWAT_RS01425
uniprot id: D8K9H0
names: Subcellular Location Annotation
messages: Cytoplasm

105559:NWAT RS10585
gene id: 105559:NWAT_RS10585
uniprot id: D8K7W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

105559:NWAT RS12300
gene id: 105559:NWAT_RS12300
uniprot id: D8K9V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

105559:NWAT RS02365
gene id: 105559:NWAT_RS02365
uniprot id: D8KAD1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

105559:NWAT RS11755
gene id: 105559:NWAT_RS11755
uniprot id: D8K977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

105559:NWAT RS15070
gene id: 105559:NWAT_RS15070
uniprot id: D8K4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

105559:NWAT RS03780
gene id: 105559:NWAT_RS03780
uniprot id: D8KBW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

105559:NWAT RS02490
gene id: 105559:NWAT_RS02490
uniprot id: D8KAF7
names: Similarity
messages: Belongs to the DEAD box helicase family.

105559:NWAT RS06495
gene id: 105559:NWAT_RS06495
uniprot id: D8K5R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

105559:NWAT RS08505
gene id: 105559:NWAT_RS08505
uniprot id: D8K6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

105559:NWAT RS07735
gene id: 105559:NWAT_RS07735
uniprot id: D8K6D9
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS05255
gene id: 105559:NWAT_RS05255
uniprot id: D8K528
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

105559:NWAT RS01235
gene id: 105559:NWAT_RS01235
uniprot id: D8K912
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

105559:NWAT RS01350
gene id: 105559:NWAT_RS01350
uniprot id: D8K9F5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

105559:NWAT RS00305
gene id: 105559:NWAT_RS00305
uniprot id: D8K853
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

105559:NWAT RS13965
gene id: 105559:NWAT_RS13965
uniprot id: D8KBH4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

105559:NWAT RS06010
gene id: 105559:NWAT_RS06010
uniprot id: D8K5H2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

105559:NWAT RS09835
gene id: 105559:NWAT_RS09835
uniprot id: D8K7G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

105559:NWAT RS01195
gene id: 105559:NWAT_RS01195
uniprot id: D8K905
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

105559:NWAT RS11775
gene id: 105559:NWAT_RS11775
uniprot id: D8K981
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

105559:NWAT RS03785
gene id: 105559:NWAT_RS03785
uniprot id: D8KBW9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

105559:NWAT RS10830
gene id: 105559:NWAT_RS10830
uniprot id: D8K8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

105559:NWAT RS01290
gene id: 105559:NWAT_RS01290
uniprot id: D8K922
names: Similarity
messages: Belongs to the phosphoribulokinase family.

105559:NWAT RS14555
gene id: 105559:NWAT_RS14555
uniprot id: D8KC59
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

105559:NWAT RS03335
gene id: 105559:NWAT_RS03335
uniprot id: D8KBM6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

105559:NWAT RS12155
gene id: 105559:NWAT_RS12155
uniprot id: D8K9T0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS00695
gene id: 105559:NWAT_RS00695
uniprot id: D8K8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

105559:NWAT RS03250
gene id: 105559:NWAT_RS03250
uniprot id: D8KB86
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

105559:NWAT RS02610
gene id: 105559:NWAT_RS02610
uniprot id: D8KAH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

105559:NWAT RS13615
gene id: 105559:NWAT_RS13615
uniprot id: D8KBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS10325
gene id: 105559:NWAT_RS10325
uniprot id: D8K7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

105559:NWAT RS02650
gene id: 105559:NWAT_RS02650
uniprot id: D8KAW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

105559:NWAT RS11135
gene id: 105559:NWAT_RS11135
uniprot id: D8K8H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

105559:NWAT RS09045
gene id: 105559:NWAT_RS09045
uniprot id: D8K724
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS13415
gene id: 105559:NWAT_RS13415
uniprot id: D8KAU8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS00015
gene id: 105559:NWAT_RS00015
uniprot id: D8K806
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

105559:NWAT RS15220
gene id: 105559:NWAT_RS15220
uniprot id: D8K4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

105559:NWAT RS14975
gene id: 105559:NWAT_RS14975
uniprot id: D8K4K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

105559:NWAT RS13655
gene id: 105559:NWAT_RS13655
uniprot id: D8KBB9
names: Similarity
messages: Belongs to the XFP family.

105559:NWAT RS02475
gene id: 105559:NWAT_RS02475
uniprot id: D8KAF4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

105559:NWAT RS11830
gene id: 105559:NWAT_RS11830
uniprot id: D8K991
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

105559:NWAT RS01135
gene id: 105559:NWAT_RS01135
uniprot id: D8K8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

105559:NWAT RS02775
gene id: 105559:NWAT_RS02775
uniprot id: D8KAZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS09360
gene id: 105559:NWAT_RS09360
uniprot id: D8K779
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS10495
gene id: 105559:NWAT_RS10495
uniprot id: D8K7U6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

105559:NWAT RS09350
gene id: 105559:NWAT_RS09350
uniprot id: D8K777
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS01070
gene id: 105559:NWAT_RS01070
uniprot id: D8K8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

105559:NWAT RS06090
gene id: 105559:NWAT_RS06090
uniprot id: D8K5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS08365
gene id: 105559:NWAT_RS08365
uniprot id: D8K6P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

105559:NWAT RS07290
gene id: 105559:NWAT_RS07290
uniprot id: D8K660
names: Similarity
messages: Belongs to the HesB/IscA family.

105559:NWAT RS10450
gene id: 105559:NWAT_RS10450
uniprot id: D8K7T7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

105559:NWAT RS11320
gene id: 105559:NWAT_RS11320
uniprot id: D8K8L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

105559:NWAT RS03045
gene id: 105559:NWAT_RS03045
uniprot id: D8KB44
names: Similarity
messages: Belongs to the Nudix hydrolase family.

105559:NWAT RS01080
gene id: 105559:NWAT_RS01080
uniprot id: D8K8Y2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10925
gene id: 105559:NWAT_RS10925
uniprot id: D8K8D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

105559:NWAT RS09340
gene id: 105559:NWAT_RS09340
uniprot id: D8K775
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS00590
gene id: 105559:NWAT_RS00590
uniprot id: D8K8A8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS06855
gene id: 105559:NWAT_RS06855
uniprot id: D8K5Y1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

105559:NWAT RS02440
gene id: 105559:NWAT_RS02440
uniprot id: D8KAE6
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

105559:NWAT RS01560
gene id: 105559:NWAT_RS01560
uniprot id: D8K9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

105559:NWAT RS01720
gene id: 105559:NWAT_RS01720
uniprot id: D8K9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

105559:NWAT RS10155
gene id: 105559:NWAT_RS10155
uniprot id: D8K7N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS15080
gene id: 105559:NWAT_RS15080
uniprot id: D8K4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

105559:NWAT RS01385
gene id: 105559:NWAT_RS01385
uniprot id: D8K9G2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

105559:NWAT RS12990
gene id: 105559:NWAT_RS12990
uniprot id: D8KAL1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

105559:NWAT RS11310
gene id: 105559:NWAT_RS11310
uniprot id: D8K8L4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

105559:NWAT RS07305
gene id: 105559:NWAT_RS07305
uniprot id: D8K663
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

105559:NWAT RS10435
gene id: 105559:NWAT_RS10435
uniprot id: D8K7T4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS06565
gene id: 105559:NWAT_RS06565
uniprot id: D8K5S8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS08885
gene id: 105559:NWAT_RS08885
uniprot id: D8K6Z3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

105559:NWAT RS07525
gene id: 105559:NWAT_RS07525
uniprot id: D8K699
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

105559:NWAT RS01260
gene id: 105559:NWAT_RS01260
uniprot id: D8K917
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

105559:NWAT RS14650
gene id: 105559:NWAT_RS14650
uniprot id: D8KC75
names: Similarity
messages: Belongs to the SCO1/2 family.

105559:NWAT RS02625
gene id: 105559:NWAT_RS02625
uniprot id: D8KAI0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

105559:NWAT RS13240
gene id: 105559:NWAT_RS13240
uniprot id: D8KAR2
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

105559:NWAT RS05525
gene id: 105559:NWAT_RS05525
uniprot id: D8K579
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

105559:NWAT RS02335
gene id: 105559:NWAT_RS02335
uniprot id: D8KAC5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS05605
gene id: 105559:NWAT_RS05605
uniprot id: D8K595
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS09065
gene id: 105559:NWAT_RS09065
uniprot id: D8K728
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS10365
gene id: 105559:NWAT_RS10365
uniprot id: D8K7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

105559:NWAT RS14475
gene id: 105559:NWAT_RS14475
uniprot id: D8KC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

105559:NWAT RS10360
gene id: 105559:NWAT_RS10360
uniprot id: D8K7R9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

105559:NWAT RS06975
gene id: 105559:NWAT_RS06975
uniprot id: D8K600
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS02360
gene id: 105559:NWAT_RS02360
uniprot id: D8KAD0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

105559:NWAT RS10625
gene id: 105559:NWAT_RS10625
uniprot id: D8K7X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

105559:NWAT RS01185
gene id: 105559:NWAT_RS01185
uniprot id: D8K903
names: Similarity
messages: Belongs to the peptidase S49 family.

105559:NWAT RS01930
gene id: 105559:NWAT_RS01930
uniprot id: D8K9R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

105559:NWAT RS08060
gene id: 105559:NWAT_RS08060
uniprot id: D8K6J7
names: Similarity
messages: Belongs to the pirin family.

105559:NWAT RS02755
gene id: 105559:NWAT_RS02755
uniprot id: D8KAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS14690
gene id: 105559:NWAT_RS14690
uniprot id: D8KC82
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

105559:NWAT RS05615
gene id: 105559:NWAT_RS05615
uniprot id: D8K597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS15130
gene id: 105559:NWAT_RS15130
uniprot id: D8K4N2
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS01950
gene id: 105559:NWAT_RS01950
uniprot id: D8K9S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

105559:NWAT RS10525
gene id: 105559:NWAT_RS10525
uniprot id: D8K7V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

105559:NWAT RS10680
gene id: 105559:NWAT_RS10680
uniprot id: D8K7X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

105559:NWAT RS15215
gene id: 105559:NWAT_RS15215
uniprot id: D8K4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

105559:NWAT RS01095
gene id: 105559:NWAT_RS01095
uniprot id: D8K8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

105559:NWAT RS09745
gene id: 105559:NWAT_RS09745
uniprot id: D8K7E9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

105559:NWAT RS01460
gene id: 105559:NWAT_RS01460
uniprot id: D8K9H7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

105559:NWAT RS05755
gene id: 105559:NWAT_RS05755
uniprot id: D8K5C6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07075
gene id: 105559:NWAT_RS07075
uniprot id: D8K621
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

105559:NWAT RS10600
gene id: 105559:NWAT_RS10600
uniprot id: D8K7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

105559:NWAT RS05595
gene id: 105559:NWAT_RS05595
uniprot id: D8K593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS03030
gene id: 105559:NWAT_RS03030
uniprot id: D8KB41
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

105559:NWAT RS12180
gene id: 105559:NWAT_RS12180
uniprot id: D8K9T5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

105559:NWAT RS09695
gene id: 105559:NWAT_RS09695
uniprot id: D8K7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

105559:NWAT RS00625
gene id: 105559:NWAT_RS00625
uniprot id: D8K8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

105559:NWAT RS02155
gene id: 105559:NWAT_RS02155
uniprot id: D8KA88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS15015
gene id: 105559:NWAT_RS15015
uniprot id: D8K4K8
names: Similarity
messages: Belongs to the SCO1/2 family.

105559:NWAT RS03470
gene id: 105559:NWAT_RS03470
uniprot id: D8KBQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

105559:NWAT RS01650
gene id: 105559:NWAT_RS01650
uniprot id: D8K9L5
names: Similarity
messages: Belongs to the UPF0758 family.

105559:NWAT RS02145
gene id: 105559:NWAT_RS02145
uniprot id: D8KA86
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

105559:NWAT RS10370
gene id: 105559:NWAT_RS10370
uniprot id: D8K7S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

105559:NWAT RS17005
gene id: 105559:NWAT_RS17005
uniprot id: D8K5X4
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the IS1 elements InsA family.

105559:NWAT RS04690
gene id: 105559:NWAT_RS04690
uniprot id: D8K4R9
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12160
gene id: 105559:NWAT_RS12160
uniprot id: D8K9T1
names: Similarity
messages: Belongs to the thioredoxin family.

105559:NWAT RS07710
gene id: 105559:NWAT_RS07710
uniprot id: D8K6D5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

105559:NWAT RS10800
gene id: 105559:NWAT_RS10800
uniprot id: D8K803
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

105559:NWAT RS01130
gene id: 105559:NWAT_RS01130
uniprot id: D8K8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

105559:NWAT RS00810
gene id: 105559:NWAT_RS00810
uniprot id: D8K8T4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

105559:NWAT RS04290
gene id: 105559:NWAT_RS04290
uniprot id: D8K4B9
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03845
gene id: 105559:NWAT_RS03845
uniprot id: D8KBX5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS03940
gene id: 105559:NWAT_RS03940
uniprot id: D8KBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS05750
gene id: 105559:NWAT_RS05750
uniprot id: D8K5C5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02130
gene id: 105559:NWAT_RS02130
uniprot id: D8KA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

105559:NWAT RS14810
gene id: 105559:NWAT_RS14810
uniprot id: D8KCA6
names: Similarity
messages: Belongs to the UPF0235 family.

105559:NWAT RS10480
gene id: 105559:NWAT_RS10480
uniprot id: D8K7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

105559:NWAT RS01400
gene id: 105559:NWAT_RS01400
uniprot id: D8K9G5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

105559:NWAT RS07245
gene id: 105559:NWAT_RS07245
uniprot id: D8K652
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

105559:NWAT RS11360
gene id: 105559:NWAT_RS11360
uniprot id: D8K8M4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

105559:NWAT RS03635
gene id: 105559:NWAT_RS03635
uniprot id: D8KBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

105559:NWAT RS11010
gene id: 105559:NWAT_RS11010
uniprot id: D8K8F2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

105559:NWAT RS07815
gene id: 105559:NWAT_RS07815
uniprot id: D8K6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

105559:NWAT RS08680
gene id: 105559:NWAT_RS08680
uniprot id: D8K6V9
names: Similarity
messages: Belongs to the asparagine synthetase family.

105559:NWAT RS10260
gene id: 105559:NWAT_RS10260
uniprot id: D8K7P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

105559:NWAT RS14465
gene id: 105559:NWAT_RS14465
uniprot id: D8KC44
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

105559:NWAT RS03695
gene id: 105559:NWAT_RS03695
uniprot id: D8KBV0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS13645
gene id: 105559:NWAT_RS13645
uniprot id: D8KBB7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07190
gene id: 105559:NWAT_RS07190
uniprot id: D8K641
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

105559:NWAT RS10195
gene id: 105559:NWAT_RS10195
uniprot id: D8K7N6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS12130
gene id: 105559:NWAT_RS12130
uniprot id: D8K9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

105559:NWAT RS11270
gene id: 105559:NWAT_RS11270
uniprot id: D8K8K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

105559:NWAT RS03050
gene id: 105559:NWAT_RS03050
uniprot id: D8KB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS13480
gene id: 105559:NWAT_RS13480
uniprot id: D8KAW1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

105559:NWAT RS11765
gene id: 105559:NWAT_RS11765
uniprot id: D8K979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

105559:NWAT RS15260
gene id: 105559:NWAT_RS15260
uniprot id: D8K4Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

105559:NWAT RS01435
gene id: 105559:NWAT_RS01435
uniprot id: D8K9H2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

105559:NWAT RS01250
gene id: 105559:NWAT_RS01250
uniprot id: D8K915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS03130
gene id: 105559:NWAT_RS03130
uniprot id: D8KB62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

105559:NWAT RS07645
gene id: 105559:NWAT_RS07645
uniprot id: D8K6C2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

105559:NWAT RS04580
gene id: 105559:NWAT_RS04580
uniprot id: D8K4H5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

105559:NWAT RS11115
gene id: 105559:NWAT_RS11115
uniprot id: D8K8H4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

105559:NWAT RS11065
gene id: 105559:NWAT_RS11065
uniprot id: D8K8G4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

105559:NWAT RS14815
gene id: 105559:NWAT_RS14815
uniprot id: D8KCA7
names: Similarity
messages: Belongs to the YggT family.

105559:NWAT RS01175
gene id: 105559:NWAT_RS01175
uniprot id: D8K901
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS03890
gene id: 105559:NWAT_RS03890
uniprot id: D8KBY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS15085
gene id: 105559:NWAT_RS15085
uniprot id: D8K4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

105559:NWAT RS07810
gene id: 105559:NWAT_RS07810
uniprot id: D8K6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

105559:NWAT RS07935
gene id: 105559:NWAT_RS07935
uniprot id: D8K6H4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

105559:NWAT RS15185
gene id: 105559:NWAT_RS15185
uniprot id: D8K4P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

105559:NWAT RS13650
gene id: 105559:NWAT_RS13650
uniprot id: D8KBB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

105559:NWAT RS01900
gene id: 105559:NWAT_RS01900
uniprot id: D8K9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

105559:NWAT RS00190
gene id: 105559:NWAT_RS00190
uniprot id: D8K833
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

105559:NWAT RS15210
gene id: 105559:NWAT_RS15210
uniprot id: D8K4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

105559:NWAT RS08820
gene id: 105559:NWAT_RS08820
uniprot id: D8K6Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

105559:NWAT RS14460
gene id: 105559:NWAT_RS14460
uniprot id: D8KC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

105559:NWAT RS10460
gene id: 105559:NWAT_RS10460
uniprot id: D8K7T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

105559:NWAT RS13410
gene id: 105559:NWAT_RS13410
uniprot id: D8KAU7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

105559:NWAT RS11800
gene id: 105559:NWAT_RS11800
uniprot id: D8K985
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

105559:NWAT RS03895
gene id: 105559:NWAT_RS03895
uniprot id: D8KBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

105559:NWAT RS10505
gene id: 105559:NWAT_RS10505
uniprot id: D8K7U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

105559:NWAT RS03330
gene id: 105559:NWAT_RS03330
uniprot id: D8KBM5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

105559:NWAT RS06775
gene id: 105559:NWAT_RS06775
uniprot id: D8K5W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

105559:NWAT RS11345
gene id: 105559:NWAT_RS11345
uniprot id: D8K8M1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

105559:NWAT RS11315
gene id: 105559:NWAT_RS11315
uniprot id: D8K8L5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

105559:NWAT RS02800
gene id: 105559:NWAT_RS02800
uniprot id: D8KAZ6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS01995
gene id: 105559:NWAT_RS01995
uniprot id: D8KA56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

105559:NWAT RS12725
gene id: 105559:NWAT_RS12725
uniprot id: D8KA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

105559:NWAT RS05420
gene id: 105559:NWAT_RS05420
uniprot id: D8K557
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

105559:NWAT RS04820
gene id: 105559:NWAT_RS04820
uniprot id: D8K4U4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

105559:NWAT RS10640
gene id: 105559:NWAT_RS10640
uniprot id: D8K7X6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS10425
gene id: 105559:NWAT_RS10425
uniprot id: D8K7T2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

105559:NWAT RS08980
gene id: 105559:NWAT_RS08980
uniprot id: D8K712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

105559:NWAT RS01415
gene id: 105559:NWAT_RS01415
uniprot id: D8K9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

105559:NWAT RS04295
gene id: 105559:NWAT_RS04295
uniprot id: D8K4C0
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

105559:NWAT RS12540
gene id: 105559:NWAT_RS12540
uniprot id: D8K9Z6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

105559:NWAT RS08905
gene id: 105559:NWAT_RS08905
uniprot id: D8K6Z7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS02520
gene id: 105559:NWAT_RS02520
uniprot id: D8KAG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

105559:NWAT RS11285
gene id: 105559:NWAT_RS11285
uniprot id: D8K8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

105559:NWAT RS14980
gene id: 105559:NWAT_RS14980
uniprot id: D8K4K1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

105559:NWAT RS11050
gene id: 105559:NWAT_RS11050
uniprot id: D8K8G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS15770
gene id: 105559:NWAT_RS15770
uniprot id: D8KBF0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

105559:NWAT RS04465
gene id: 105559:NWAT_RS04465
uniprot id: D8K4F2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

105559:NWAT RS13035
gene id: 105559:NWAT_RS13035
uniprot id: D8KAM0
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS07135
gene id: 105559:NWAT_RS07135
uniprot id: D8K630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

105559:NWAT RS09170
gene id: 105559:NWAT_RS09170
uniprot id: D8K747
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

105559:NWAT RS00860
gene id: 105559:NWAT_RS00860
uniprot id: D8K8U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

105559:NWAT RS05035
gene id: 105559:NWAT_RS05035
uniprot id: D8K4Y6
names: Similarity
messages: Belongs to the peptidase M16 family.

105559:NWAT RS09060
gene id: 105559:NWAT_RS09060
uniprot id: D8K727
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS02760
gene id: 105559:NWAT_RS02760
uniprot id: D8KAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS00180
gene id: 105559:NWAT_RS00180
uniprot id: D8K831
names: Subcellular Location Annotation
messages: Mitochondrion

105559:NWAT RS14120
gene id: 105559:NWAT_RS14120
uniprot id: D8KBK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

105559:NWAT RS00595
gene id: 105559:NWAT_RS00595
uniprot id: D8K8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

105559:NWAT RS14060
gene id: 105559:NWAT_RS14060
uniprot id: D8KBJ1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

105559:NWAT RS02665
gene id: 105559:NWAT_RS02665
uniprot id: D8KAW9
names: Similarity
messages: Belongs to the peptidase M24B family.

105559:NWAT RS03450
gene id: 105559:NWAT_RS03450
uniprot id: D8KBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

105559:NWAT RS01860
gene id: 105559:NWAT_RS01860
uniprot id: D8K9Q5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

105559:NWAT RS06235
gene id: 105559:NWAT_RS06235
uniprot id: D8K5L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

105559:NWAT RS01405
gene id: 105559:NWAT_RS01405
uniprot id: D8K9G6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS14910
gene id: 105559:NWAT_RS14910
uniprot id: D8K4I9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

105559:NWAT RS01035
gene id: 105559:NWAT_RS01035
uniprot id: D8K8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

105559:NWAT RS08225
gene id: 105559:NWAT_RS08225
uniprot id: D8K6N0
names: Similarity
messages: Belongs to the universal stress protein A family.

105559:NWAT RS03935
gene id: 105559:NWAT_RS03935
uniprot id: D8KBZ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

105559:NWAT RS04970
gene id: 105559:NWAT_RS04970
uniprot id: D8K4X3
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02170
gene id: 105559:NWAT_RS02170
uniprot id: D8KA91
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS15470
gene id: 105559:NWAT_RS15470
uniprot id: D8KCF9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS02165
gene id: 105559:NWAT_RS02165
uniprot id: D8KA90
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

105559:NWAT RS07385
gene id: 105559:NWAT_RS07385
uniprot id: D8K673
names: Similarity
messages: Belongs to the band 7/mec-2 family.

105559:NWAT RS00840
gene id: 105559:NWAT_RS00840
uniprot id: D8K8U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS01475
gene id: 105559:NWAT_RS01475
uniprot id: D8K9I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

105559:NWAT RS06560
gene id: 105559:NWAT_RS06560
uniprot id: D8K5S7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS09690
gene id: 105559:NWAT_RS09690
uniprot id: D8K7D8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

105559:NWAT RS03910
gene id: 105559:NWAT_RS03910
uniprot id: D8KBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

105559:NWAT RS02235
gene id: 105559:NWAT_RS02235
uniprot id: D8KAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

105559:NWAT RS11445
gene id: 105559:NWAT_RS11445
uniprot id: D8K8P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

105559:NWAT RS12555
gene id: 105559:NWAT_RS12555
uniprot id: D8K9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

105559:NWAT RS09330
gene id: 105559:NWAT_RS09330
uniprot id: D8K773
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

105559:NWAT RS11475
gene id: 105559:NWAT_RS11475
uniprot id: D8K925
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

105559:NWAT RS03535
gene id: 105559:NWAT_RS03535
uniprot id: D8KBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

105559:NWAT RS04870
gene id: 105559:NWAT_RS04870
uniprot id: D8K4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

105559:NWAT RS10820
gene id: 105559:NWAT_RS10820
uniprot id: D8K8B4
names: Subcellular Location Annotation
messages: Cytoplasm

105559:NWAT RS01550
gene id: 105559:NWAT_RS01550
uniprot id: D8K9J5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

105559:NWAT RS03670
gene id: 105559:NWAT_RS03670
uniprot id: D8KBU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

105559:NWAT RS09125
gene id: 105559:NWAT_RS09125
uniprot id: D8K738
names: Similarity
messages: Belongs to the UPF0047 family.

105559:NWAT RS07500
gene id: 105559:NWAT_RS07500
uniprot id: D8K694
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

105559:NWAT RS08195
gene id: 105559:NWAT_RS08195
uniprot id: D8K6M3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS09005
gene id: 105559:NWAT_RS09005
uniprot id: D8K717
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

105559:NWAT RS05490
gene id: 105559:NWAT_RS05490
uniprot id: D8K573
names: Similarity
messages: Belongs to the ABC transporter superfamily.

105559:NWAT RS07185
gene id: 105559:NWAT_RS07185
uniprot id: D8K640
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

105559:NWAT RS11750
gene id: 105559:NWAT_RS11750
uniprot id: D8K976
names: Similarity
messages: Belongs to the P(II) protein family.

105559:NWAT RS04810
gene id: 105559:NWAT_RS04810
uniprot id: D8K4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

105559:NWAT RS10715
gene id: 105559:NWAT_RS10715
uniprot id: D8K7W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

105559:NWAT RS05415
gene id: 105559:NWAT_RS05415
uniprot id: D8K556
names: Similarity
messages: Belongs to the RutC family.

105559:NWAT RS03235
gene id: 105559:NWAT_RS03235
uniprot id: D8KB83
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

105559:NWAT RS03290
gene id: 105559:NWAT_RS03290
uniprot id: D8KB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

105559:NWAT RS04555
gene id: 105559:NWAT_RS04555
uniprot id: D8K4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

105559:NWAT RS03295
gene id: 105559:NWAT_RS03295
uniprot id: D8KB95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

105559:NWAT RS03180
gene id: 105559:NWAT_RS03180
uniprot id: D8KB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

105559:NWAT RS08695
gene id: 105559:NWAT_RS08695
uniprot id: D8K6W2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

105559:NWAT RS07795
gene id: 105559:NWAT_RS07795
uniprot id: D8K6E8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

105559:NWAT RS10840
gene id: 105559:NWAT_RS10840
uniprot id: D8K8B8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

105559:NWAT RS03630
gene id: 105559:NWAT_RS03630
uniprot id: D8KBT8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

105559:NWAT RS02395
gene id: 105559:NWAT_RS02395
uniprot id: D8KAD7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

105559:NWAT RS13275
gene id: 105559:NWAT_RS13275
uniprot id: D8KAR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

105559:NWAT RS15435
gene id: 105559:NWAT_RS15435
uniprot id: D8KCF3
names: Similarity
messages: Belongs to the ParB family.

105559:NWAT RS06715
gene id: 105559:NWAT_RS06715
uniprot id: D8K5V4
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

105559:NWAT RS03155
gene id: 105559:NWAT_RS03155
uniprot id: D8KB67
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

105559:NWAT RS04340
gene id: 105559:NWAT_RS04340
uniprot id: D8K4C8
names: Similarity
messages: Belongs to the universal stress protein A family.

105559:NWAT RS11460
gene id: 105559:NWAT_RS11460
uniprot id: D8K8P5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS00445
gene id: 105559:NWAT_RS00445
uniprot id: D8K878
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

105559:NWAT RS10510
gene id: 105559:NWAT_RS10510
uniprot id: D8K7U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

105559:NWAT RS07010
gene id: 105559:NWAT_RS07010
uniprot id: D8K607
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

105559:NWAT RS07555
gene id: 105559:NWAT_RS07555
uniprot id: D8K6A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS09830
gene id: 105559:NWAT_RS09830
uniprot id: D8K7G5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

105559:NWAT RS15245
gene id: 105559:NWAT_RS15245
uniprot id: D8K4Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

105559:NWAT RS14055
gene id: 105559:NWAT_RS14055
uniprot id: D8KBJ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

105559:NWAT RS04930
gene id: 105559:NWAT_RS04930
uniprot id: D8K4W5
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

105559:NWAT RS07035
gene id: 105559:NWAT_RS07035
uniprot id: D8K612
names: Similarity
messages: Belongs to the heat shock protein 70 family.

105559:NWAT RS05945
gene id: 105559:NWAT_RS05945
uniprot id: D8K5G1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

105559:NWAT RS10205
gene id: 105559:NWAT_RS10205
uniprot id: D8K7N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS17505
gene id: 105559:NWAT_RS17505
uniprot id: D8K8B2
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

105559:NWAT RS02550
gene id: 105559:NWAT_RS02550
uniprot id: D8KAG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

105559:NWAT RS07875
gene id: 105559:NWAT_RS07875
uniprot id: D8K6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

105559:NWAT RS04285
gene id: 105559:NWAT_RS04285
uniprot id: D8K4B8
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

105559:NWAT RS10070
gene id: 105559:NWAT_RS10070
uniprot id: D8K7L3
names: Similarity
messages: Belongs to the MlaA family.

105559:NWAT RS06340
gene id: 105559:NWAT_RS06340
uniprot id: D8K5N5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS07865
gene id: 105559:NWAT_RS07865
uniprot id: D8K6G0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

105559:NWAT RS08930
gene id: 105559:NWAT_RS08930
uniprot id: D8K701
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

105559:NWAT RS01970
gene id: 105559:NWAT_RS01970
uniprot id: D8K9S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

105559:NWAT RS04355
gene id: 105559:NWAT_RS04355
uniprot id: D8K4D1
names: Similarity
messages: Belongs to the PrpD family.

105559:NWAT RS06605
gene id: 105559:NWAT_RS06605
uniprot id: D8K5T4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

105559:NWAT RS00460
gene id: 105559:NWAT_RS00460
uniprot id: D8K881
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

105559:NWAT RS14030
gene id: 105559:NWAT_RS14030
uniprot id: D8KBI6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

105559:NWAT RS05245
gene id: 105559:NWAT_RS05245
uniprot id: D8K526
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

105559:NWAT RS03580
gene id: 105559:NWAT_RS03580
uniprot id: D8KBT0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

105559:NWAT RS10915
gene id: 105559:NWAT_RS10915
uniprot id: D8K8D3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

105559:NWAT RS08815
gene id: 105559:NWAT_RS08815
uniprot id: D8K6Y1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS13400
gene id: 105559:NWAT_RS13400
uniprot id: D8KAU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

105559:NWAT RS01030
gene id: 105559:NWAT_RS01030
uniprot id: D8K8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

105559:NWAT RS08590
gene id: 105559:NWAT_RS08590
uniprot id: D8K6U2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

105559:NWAT RS02710
gene id: 105559:NWAT_RS02710
uniprot id: D8KAX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

105559:NWAT RS09070
gene id: 105559:NWAT_RS09070
uniprot id: D8K729
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

105559:NWAT RS09905
gene id: 105559:NWAT_RS09905
uniprot id: D8K7I0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

105559:NWAT RS05215
gene id: 105559:NWAT_RS05215
uniprot id: D8K520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

105559:NWAT RS02280
gene id: 105559:NWAT_RS02280
uniprot id: D8KAB4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

105559:NWAT RS10670
gene id: 105559:NWAT_RS10670
uniprot id: D8K7W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

105559:NWAT RS09100
gene id: 105559:NWAT_RS09100
uniprot id: D8K734
names: Similarity
messages: Belongs to the peptidase S9C family.

105559:NWAT RS04960
gene id: 105559:NWAT_RS04960
uniprot id: D8K4X1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

105559:NWAT RS00510
gene id: 105559:NWAT_RS00510
uniprot id: D8K892
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02500
gene id: 105559:NWAT_RS02500
uniprot id: D8KAF9
names: Subcellular Location Annotation
messages: Cytoplasm

105559:NWAT RS10910
gene id: 105559:NWAT_RS10910
uniprot id: D8K8D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

105559:NWAT RS14875
gene id: 105559:NWAT_RS14875
uniprot id: D8KCB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS14830
gene id: 105559:NWAT_RS14830
uniprot id: D8KCB0
names: Similarity
messages: Belongs to the GSP E family.

105559:NWAT RS05405
gene id: 105559:NWAT_RS05405
uniprot id: D8K554
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

105559:NWAT RS01655
gene id: 105559:NWAT_RS01655
uniprot id: D8K9L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS05800
gene id: 105559:NWAT_RS05800
uniprot id: D8K5D4
names: Similarity
messages: Belongs to the universal stress protein A family.

105559:NWAT RS05870
gene id: 105559:NWAT_RS05870
uniprot id: D8K5E8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

105559:NWAT RS13665
gene id: 105559:NWAT_RS13665
uniprot id: D8KBC1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS06580
gene id: 105559:NWAT_RS06580
uniprot id: D8K5T1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

105559:NWAT RS09855
gene id: 105559:NWAT_RS09855
uniprot id: D8K7H0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS01790
gene id: 105559:NWAT_RS01790
uniprot id: D8K9P4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

105559:NWAT RS07720
gene id: 105559:NWAT_RS07720
uniprot id: D8K6D6
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

105559:NWAT RS06345
gene id: 105559:NWAT_RS06345
uniprot id: D8K5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS09355
gene id: 105559:NWAT_RS09355
uniprot id: D8K778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS00890
gene id: 105559:NWAT_RS00890
uniprot id: D8K8V0
names: Similarity
messages: Belongs to the ArsC family.

105559:NWAT RS11770
gene id: 105559:NWAT_RS11770
uniprot id: D8K980
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS11305
gene id: 105559:NWAT_RS11305
uniprot id: D8K8L3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

105559:NWAT RS00485
gene id: 105559:NWAT_RS00485
uniprot id: D8K887
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS09705
gene id: 105559:NWAT_RS09705
uniprot id: D8K7E1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

105559:NWAT RS10135
gene id: 105559:NWAT_RS10135
uniprot id: D8K7M6
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

105559:NWAT RS00200
gene id: 105559:NWAT_RS00200
uniprot id: D8K835
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

105559:NWAT RS13440
gene id: 105559:NWAT_RS13440
uniprot id: D8KAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

105559:NWAT RS01375
gene id: 105559:NWAT_RS01375
uniprot id: D8K9G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

105559:NWAT RS13540
gene id: 105559:NWAT_RS13540
uniprot id: D8KB98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02175
gene id: 105559:NWAT_RS02175
uniprot id: D8KA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

105559:NWAT RS10885
gene id: 105559:NWAT_RS10885
uniprot id: D8K8C7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

105559:NWAT RS00575
gene id: 105559:NWAT_RS00575
uniprot id: D8K8A6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

105559:NWAT RS02060
gene id: 105559:NWAT_RS02060
uniprot id: D8KA69
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

105559:NWAT RS08510
gene id: 105559:NWAT_RS08510
uniprot id: D8K6S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

105559:NWAT RS04795
gene id: 105559:NWAT_RS04795
uniprot id: D8K4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

105559:NWAT RS06485
gene id: 105559:NWAT_RS06485
uniprot id: D8K5R5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

105559:NWAT RS03300
gene id: 105559:NWAT_RS03300
uniprot id: D8KBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

105559:NWAT RS13735
gene id: 105559:NWAT_RS13735
uniprot id: D8KBD4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

105559:NWAT RS10575
gene id: 105559:NWAT_RS10575
uniprot id: D8K7W3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

105559:NWAT RS13710
gene id: 105559:NWAT_RS13710
uniprot id: D8KBC9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

105559:NWAT RS06410
gene id: 105559:NWAT_RS06410
uniprot id: D8K5P9
names: Similarity
messages: Belongs to the IucA/IucC family.

105559:NWAT RS10405
gene id: 105559:NWAT_RS10405
uniprot id: D8K7S8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

105559:NWAT RS09190
gene id: 105559:NWAT_RS09190
uniprot id: D8K751
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02370
gene id: 105559:NWAT_RS02370
uniprot id: D8KAD2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

105559:NWAT RS14245
gene id: 105559:NWAT_RS14245
uniprot id: D8KC03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

105559:NWAT RS04935
gene id: 105559:NWAT_RS04935
uniprot id: D8K4W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

105559:NWAT RS12345
gene id: 105559:NWAT_RS12345
uniprot id: D8K9W3
names: Similarity
messages: Belongs to the asparagine synthetase family.

105559:NWAT RS11045
gene id: 105559:NWAT_RS11045
uniprot id: D8K8G0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

105559:NWAT RS08265
gene id: 105559:NWAT_RS08265
uniprot id: D8K6N7
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

105559:NWAT RS01015
gene id: 105559:NWAT_RS01015
uniprot id: D8K8X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

105559:NWAT RS12945
gene id: 105559:NWAT_RS12945
uniprot id: D8KAK3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS03885
gene id: 105559:NWAT_RS03885
uniprot id: D8KBY2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

105559:NWAT RS00620
gene id: 105559:NWAT_RS00620
uniprot id: D8K8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

105559:NWAT RS10805
gene id: 105559:NWAT_RS10805
uniprot id: D8K804
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

105559:NWAT RS10470
gene id: 105559:NWAT_RS10470
uniprot id: D8K7U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

105559:NWAT RS01380
gene id: 105559:NWAT_RS01380
uniprot id: D8K9G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

105559:NWAT RS11225
gene id: 105559:NWAT_RS11225
uniprot id: D8K8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

105559:NWAT RS03005
gene id: 105559:NWAT_RS03005
uniprot id: D8KB36
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

105559:NWAT RS03315
gene id: 105559:NWAT_RS03315
uniprot id: D8KBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS11325
gene id: 105559:NWAT_RS11325
uniprot id: D8K8L7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

105559:NWAT RS12415
gene id: 105559:NWAT_RS12415
uniprot id: D8K9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

105559:NWAT RS13455
gene id: 105559:NWAT_RS13455
uniprot id: D8KAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

105559:NWAT RS15020
gene id: 105559:NWAT_RS15020
uniprot id: D8K4K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS14035
gene id: 105559:NWAT_RS14035
uniprot id: D8KBI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

105559:NWAT RS02415
gene id: 105559:NWAT_RS02415
uniprot id: D8KAE1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

105559:NWAT RS15190
gene id: 105559:NWAT_RS15190
uniprot id: D8K4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

105559:NWAT RS02795
gene id: 105559:NWAT_RS02795
uniprot id: D8KAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS03010
gene id: 105559:NWAT_RS03010
uniprot id: D8KB37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

105559:NWAT RS10530
gene id: 105559:NWAT_RS10530
uniprot id: D8K7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

105559:NWAT RS06785
gene id: 105559:NWAT_RS06785
uniprot id: D8K5W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

105559:NWAT RS14970
gene id: 105559:NWAT_RS14970
uniprot id: D8K4J9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

105559:NWAT RS10785
gene id: 105559:NWAT_RS10785
uniprot id: D8K800
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

105559:NWAT RS02125
gene id: 105559:NWAT_RS02125
uniprot id: D8KA82
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

105559:NWAT RS13355
gene id: 105559:NWAT_RS13355
uniprot id: D8KAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

105559:NWAT RS05425
gene id: 105559:NWAT_RS05425
uniprot id: D8K558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

105559:NWAT RS02605
gene id: 105559:NWAT_RS02605
uniprot id: D8KAH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS07115
gene id: 105559:NWAT_RS07115
uniprot id: D8K626
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12680
gene id: 105559:NWAT_RS12680
uniprot id: D8KA20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

105559:NWAT RS00350
gene id: 105559:NWAT_RS00350
uniprot id: D8K863
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

105559:NWAT RS02035
gene id: 105559:NWAT_RS02035
uniprot id: D8KA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

105559:NWAT RS10350
gene id: 105559:NWAT_RS10350
uniprot id: D8K7R7
names: Similarity
messages: Belongs to the SfsA family.

105559:NWAT RS01240
gene id: 105559:NWAT_RS01240
uniprot id: D8K913
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS04160
gene id: 105559:NWAT_RS04160
uniprot id: D8K495
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

105559:NWAT RS06835
gene id: 105559:NWAT_RS06835
uniprot id: D8K5X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

105559:NWAT RS09765
gene id: 105559:NWAT_RS09765
uniprot id: D8K7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS11210
gene id: 105559:NWAT_RS11210
uniprot id: D8K8J4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

105559:NWAT RS10245
gene id: 105559:NWAT_RS10245
uniprot id: D8K7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

105559:NWAT RS10875
gene id: 105559:NWAT_RS10875
uniprot id: D8K8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

105559:NWAT RS08150
gene id: 105559:NWAT_RS08150
uniprot id: D8K6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Belongs to the ribosome association toxin RatA family.
messages: Membrane

105559:NWAT RS11350
gene id: 105559:NWAT_RS11350
uniprot id: D8K8M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

105559:NWAT RS09180
gene id: 105559:NWAT_RS09180
uniprot id: D8K749
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

105559:NWAT RS02655
gene id: 105559:NWAT_RS02655
uniprot id: D8KAW7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

105559:NWAT RS09875
gene id: 105559:NWAT_RS09875
uniprot id: D8K7H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS01310
gene id: 105559:NWAT_RS01310
uniprot id: D8K9E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

105559:NWAT RS14985
gene id: 105559:NWAT_RS14985
uniprot id: D8K4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS02635
gene id: 105559:NWAT_RS02635
uniprot id: D8KAI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

105559:NWAT RS03000
gene id: 105559:NWAT_RS03000
uniprot id: D8KB35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

105559:NWAT RS15550
gene id: 105559:NWAT_RS15550
uniprot id: D8KAY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

105559:NWAT RS06385
gene id: 105559:NWAT_RS06385
uniprot id: D8K5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

105559:NWAT RS06645
gene id: 105559:NWAT_RS06645
uniprot id: D8K5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

105559:NWAT RS02150
gene id: 105559:NWAT_RS02150
uniprot id: D8KA87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

105559:NWAT RS04875
gene id: 105559:NWAT_RS04875
uniprot id: D8K4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

105559:NWAT RS08495
gene id: 105559:NWAT_RS08495
uniprot id: D8K6S4
names: Similarity
messages: Belongs to the peptidase M16 family.

105559:NWAT RS03380
gene id: 105559:NWAT_RS03380
uniprot id: D8KBN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

105559:NWAT RS01230
gene id: 105559:NWAT_RS01230
uniprot id: D8K911
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

105559:NWAT RS04605
gene id: 105559:NWAT_RS04605
uniprot id: D8K4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

105559:NWAT RS10565
gene id: 105559:NWAT_RS10565
uniprot id: D8K7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

105559:NWAT RS08280
gene id: 105559:NWAT_RS08280
uniprot id: D8K6P0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

105559:NWAT RS14785
gene id: 105559:NWAT_RS14785
uniprot id: D8KCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

105559:NWAT RS12125
gene id: 105559:NWAT_RS12125
uniprot id: D8K9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

105559:NWAT RS04200
gene id: 105559:NWAT_RS04200
uniprot id: D8K4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS02405
gene id: 105559:NWAT_RS02405
uniprot id: D8KAD9
names: Similarity
messages: Belongs to the citrate synthase family.

105559:NWAT RS09770
gene id: 105559:NWAT_RS09770
uniprot id: D8K7F4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS09375
gene id: 105559:NWAT_RS09375
uniprot id: D8K782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS03495
gene id: 105559:NWAT_RS03495
uniprot id: D8KBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS06800
gene id: 105559:NWAT_RS06800
uniprot id: D8K5X0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

105559:NWAT RS10290
gene id: 105559:NWAT_RS10290
uniprot id: D8K7Q5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

105559:NWAT RS10740
gene id: 105559:NWAT_RS10740
uniprot id: D8K7Z1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

105559:NWAT RS04955
gene id: 105559:NWAT_RS04955
uniprot id: D8K4X0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

105559:NWAT RS11290
gene id: 105559:NWAT_RS11290
uniprot id: D8K8L0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

105559:NWAT RS03700
gene id: 105559:NWAT_RS03700
uniprot id: D8KBV1
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 8 heme c groups per subunit. One specific heme c group is called heme P460.
messages: Binds 8 heme groups per subunit.
messages: Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554.
messages: Homotrimer.
messages: Periplasm

105559:NWAT RS05830
gene id: 105559:NWAT_RS05830
uniprot id: D8K5E0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

105559:NWAT RS10880
gene id: 105559:NWAT_RS10880
uniprot id: D8K8C6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

105559:NWAT RS03765
gene id: 105559:NWAT_RS03765
uniprot id: D8KBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

105559:NWAT RS09315
gene id: 105559:NWAT_RS09315
uniprot id: D8K770
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS13270
gene id: 105559:NWAT_RS13270
uniprot id: D8KAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

105559:NWAT RS14170
gene id: 105559:NWAT_RS14170
uniprot id: D8KBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

105559:NWAT RS01075
gene id: 105559:NWAT_RS01075
uniprot id: D8K8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

105559:NWAT RS06840
gene id: 105559:NWAT_RS06840
uniprot id: D8K5X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

105559:NWAT RS09175
gene id: 105559:NWAT_RS09175
uniprot id: D8K748
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

105559:NWAT RS05280
gene id: 105559:NWAT_RS05280
uniprot id: D8K533
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

105559:NWAT RS12110
gene id: 105559:NWAT_RS12110
uniprot id: D8K9D5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

105559:NWAT RS04965
gene id: 105559:NWAT_RS04965
uniprot id: D8K4X2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

105559:NWAT RS03980
gene id: 105559:NWAT_RS03980
uniprot id: D8K464
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

105559:NWAT RS12550
gene id: 105559:NWAT_RS12550
uniprot id: D8K9Z7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

105559:NWAT RS03945
gene id: 105559:NWAT_RS03945
uniprot id: D8KBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

105559:NWAT RS09685
gene id: 105559:NWAT_RS09685
uniprot id: D8K7D7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

105559:NWAT RS09760
gene id: 105559:NWAT_RS09760
uniprot id: D8K7F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS08685
gene id: 105559:NWAT_RS08685
uniprot id: D8K6W0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

105559:NWAT RS10595
gene id: 105559:NWAT_RS10595
uniprot id: D8K7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

105559:NWAT RS00885
gene id: 105559:NWAT_RS00885
uniprot id: D8K8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

105559:NWAT RS13485
gene id: 105559:NWAT_RS13485
uniprot id: D8KAW2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

105559:NWAT RS09325
gene id: 105559:NWAT_RS09325
uniprot id: D8K772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS10580
gene id: 105559:NWAT_RS10580
uniprot id: D8K7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

105559:NWAT RS01675
gene id: 105559:NWAT_RS01675
uniprot id: D8K9M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS11435
gene id: 105559:NWAT_RS11435
uniprot id: D8K8P0
names: Similarity
messages: Belongs to the asparagine synthetase family.

105559:NWAT RS05855
gene id: 105559:NWAT_RS05855
uniprot id: D8K5E5
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

105559:NWAT RS02250
gene id: 105559:NWAT_RS02250
uniprot id: D8KAA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

105559:NWAT RS11235
gene id: 105559:NWAT_RS11235
uniprot id: D8K8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

105559:NWAT RS06740
gene id: 105559:NWAT_RS06740
uniprot id: D8K5V8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS12625
gene id: 105559:NWAT_RS12625
uniprot id: D8KA11
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

105559:NWAT RS00070
gene id: 105559:NWAT_RS00070
uniprot id: D8K809
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

105559:NWAT RS08830
gene id: 105559:NWAT_RS08830
uniprot id: D8K6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

105559:NWAT RS14770
gene id: 105559:NWAT_RS14770
uniprot id: D8KC98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS08960
gene id: 105559:NWAT_RS08960
uniprot id: D8K708
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS14635
gene id: 105559:NWAT_RS14635
uniprot id: D8KC72
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

105559:NWAT RS02630
gene id: 105559:NWAT_RS02630
uniprot id: D8KAI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

105559:NWAT RS14820
gene id: 105559:NWAT_RS14820
uniprot id: D8KCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

105559:NWAT RS02810
gene id: 105559:NWAT_RS02810
uniprot id: D8KAZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

105559:NWAT RS08395
gene id: 105559:NWAT_RS08395
uniprot id: D8K6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

105559:NWAT RS02770
gene id: 105559:NWAT_RS02770
uniprot id: D8KAZ0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

105559:NWAT RS04575
gene id: 105559:NWAT_RS04575
uniprot id: D8K4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

105559:NWAT RS10540
gene id: 105559:NWAT_RS10540
uniprot id: D8K7V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

105559:NWAT RS04535
gene id: 105559:NWAT_RS04535
uniprot id: D8K4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

105559:NWAT RS13010
gene id: 105559:NWAT_RS13010
uniprot id: D8KAL5
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS11145
gene id: 105559:NWAT_RS11145
uniprot id: D8K8I0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

105559:NWAT RS13565
gene id: 105559:NWAT_RS13565
uniprot id: D8KBA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

105559:NWAT RS13315
gene id: 105559:NWAT_RS13315
uniprot id: D8KAS7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

105559:NWAT RS06085
gene id: 105559:NWAT_RS06085
uniprot id: D8K5I7
names: Similarity
messages: Belongs to the GSP E family.

105559:NWAT RS01565
gene id: 105559:NWAT_RS01565
uniprot id: D8K9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS07210
gene id: 105559:NWAT_RS07210
uniprot id: D8K645
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

105559:NWAT RS05355
gene id: 105559:NWAT_RS05355
uniprot id: D8K544
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

105559:NWAT RS06370
gene id: 105559:NWAT_RS06370
uniprot id: D8K5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

105559:NWAT RS07515
gene id: 105559:NWAT_RS07515
uniprot id: D8K697
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

105559:NWAT RS00605
gene id: 105559:NWAT_RS00605
uniprot id: D8K8B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

105559:NWAT RS14905
gene id: 105559:NWAT_RS14905
uniprot id: D8KCB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

105559:NWAT RS15195
gene id: 105559:NWAT_RS15195
uniprot id: D8K4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

105559:NWAT RS12820
gene id: 105559:NWAT_RS12820
uniprot id: D8KA45
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS11465
gene id: 105559:NWAT_RS11465
uniprot id: D8K8P6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

105559:NWAT RS04330
gene id: 105559:NWAT_RS04330
uniprot id: D8K4C6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS10815
gene id: 105559:NWAT_RS10815
uniprot id: D8K8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS11220
gene id: 105559:NWAT_RS11220
uniprot id: D8K8J6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

105559:NWAT RS04865
gene id: 105559:NWAT_RS04865
uniprot id: D8K4V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

105559:NWAT RS07730
gene id: 105559:NWAT_RS07730
uniprot id: D8K6D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

105559:NWAT RS12785
gene id: 105559:NWAT_RS12785
uniprot id: D8KA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

105559:NWAT RS11455
gene id: 105559:NWAT_RS11455
uniprot id: D8K8P4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

105559:NWAT RS05240
gene id: 105559:NWAT_RS05240
uniprot id: D8K525
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

105559:NWAT RS07925
gene id: 105559:NWAT_RS07925
uniprot id: D8K6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

105559:NWAT RS03850
gene id: 105559:NWAT_RS03850
uniprot id: D8KBX6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

105559:NWAT RS02715
gene id: 105559:NWAT_RS02715
uniprot id: D8KAY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS01300
gene id: 105559:NWAT_RS01300
uniprot id: D8K9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

105559:NWAT RS14940
gene id: 105559:NWAT_RS14940
uniprot id: D8K4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

105559:NWAT RS01665
gene id: 105559:NWAT_RS01665
uniprot id: D8K9L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

105559:NWAT RS01455
gene id: 105559:NWAT_RS01455
uniprot id: D8K9H6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

105559:NWAT RS07675
gene id: 105559:NWAT_RS07675
uniprot id: D8K6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

105559:NWAT RS04550
gene id: 105559:NWAT_RS04550
uniprot id: D8K4G9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

105559:NWAT RS01140
gene id: 105559:NWAT_RS01140
uniprot id: D8K8Z4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

105559:NWAT RS06850
gene id: 105559:NWAT_RS06850
uniprot id: D8K5Y0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

105559:NWAT RS03375
gene id: 105559:NWAT_RS03375
uniprot id: D8KBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

105559:NWAT RS01065
gene id: 105559:NWAT_RS01065
uniprot id: D8K8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

105559:NWAT RS15465
gene id: 105559:NWAT_RS15465
uniprot id: D8KCF8
names: Similarity
messages: Belongs to the DNase I family.

105559:NWAT RS00550
gene id: 105559:NWAT_RS00550
uniprot id: D8K8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

105559:NWAT RS02220
gene id: 105559:NWAT_RS02220
uniprot id: D8KAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

105559:NWAT RS09820
gene id: 105559:NWAT_RS09820
uniprot id: D8K7G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS04320
gene id: 105559:NWAT_RS04320
uniprot id: D8K4C4
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS01330
gene id: 105559:NWAT_RS01330
uniprot id: D8K9F1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS06830
gene id: 105559:NWAT_RS06830
uniprot id: D8K5X6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

105559:NWAT RS01100
gene id: 105559:NWAT_RS01100
uniprot id: D8K8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

105559:NWAT RS02915
gene id: 105559:NWAT_RS02915
uniprot id: D8KB19
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS14895
gene id: 105559:NWAT_RS14895
uniprot id: D8KCB7
names: Similarity
messages: Belongs to the DprA/Smf family.

105559:NWAT RS12575
gene id: 105559:NWAT_RS12575
uniprot id: D8KA01
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

105559:NWAT RS04455
gene id: 105559:NWAT_RS04455
uniprot id: D8K4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

105559:NWAT RS01365
gene id: 105559:NWAT_RS01365
uniprot id: D8K9F8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

105559:NWAT RS10760
gene id: 105559:NWAT_RS10760
uniprot id: D8K7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

105559:NWAT RS11110
gene id: 105559:NWAT_RS11110
uniprot id: D8K8H3
names: Similarity
messages: Belongs to the peptidase S49 family.

105559:NWAT RS11430
gene id: 105559:NWAT_RS11430
uniprot id: D8K8N9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

105559:NWAT RS03460
gene id: 105559:NWAT_RS03460
uniprot id: D8KBQ4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

105559:NWAT RS11450
gene id: 105559:NWAT_RS11450
uniprot id: D8K8P3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

105559:NWAT RS11165
gene id: 105559:NWAT_RS11165
uniprot id: D8K8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

105559:NWAT RS13960
gene id: 105559:NWAT_RS13960
uniprot id: D8KBH3
names: Similarity
messages: Belongs to the YoeB family.

105559:NWAT RS10255
gene id: 105559:NWAT_RS10255
uniprot id: D8K7P8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

105559:NWAT RS03025
gene id: 105559:NWAT_RS03025
uniprot id: D8KB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

105559:NWAT RS16990
gene id: 105559:NWAT_RS16990
uniprot id: D8K5X5
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

105559:NWAT RS11470
gene id: 105559:NWAT_RS11470
uniprot id: D8K924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

105559:NWAT RS11425
gene id: 105559:NWAT_RS11425
uniprot id: D8K8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

105559:NWAT RS14070
gene id: 105559:NWAT_RS14070
uniprot id: D8KBJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

105559:NWAT RS01990
gene id: 105559:NWAT_RS01990
uniprot id: D8KA55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

105559:NWAT RS10675
gene id: 105559:NWAT_RS10675
uniprot id: D8K7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

105559:NWAT RS07170
gene id: 105559:NWAT_RS07170
uniprot id: D8K637
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

105559:NWAT RS03280
gene id: 105559:NWAT_RS03280
uniprot id: D8KB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

105559:NWAT RS13995
gene id: 105559:NWAT_RS13995
uniprot id: D8KBH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

105559:NWAT RS09365
gene id: 105559:NWAT_RS09365
uniprot id: D8K780
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10465
gene id: 105559:NWAT_RS10465
uniprot id: D8K7U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

105559:NWAT RS05860
gene id: 105559:NWAT_RS05860
uniprot id: D8K5E6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

105559:NWAT RS12105
gene id: 105559:NWAT_RS12105
uniprot id: D8K9D4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

105559:NWAT RS09710
gene id: 105559:NWAT_RS09710
uniprot id: D8K7E2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

105559:NWAT RS11980
gene id: 105559:NWAT_RS11980
uniprot id: D8K9B5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

105559:NWAT RS02700
gene id: 105559:NWAT_RS02700
uniprot id: D8KAX6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS01160
gene id: 105559:NWAT_RS01160
uniprot id: D8K8Z8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

105559:NWAT RS04610
gene id: 105559:NWAT_RS04610
uniprot id: D8K4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

105559:NWAT RS14455
gene id: 105559:NWAT_RS14455
uniprot id: D8KC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

105559:NWAT RS01085
gene id: 105559:NWAT_RS01085
uniprot id: D8K8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

105559:NWAT RS04450
gene id: 105559:NWAT_RS04450
uniprot id: D8K4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

105559:NWAT RS01485
gene id: 105559:NWAT_RS01485
uniprot id: D8K9I2
names: Similarity
messages: Belongs to the MlaA family.

105559:NWAT RS02100
gene id: 105559:NWAT_RS02100
uniprot id: D8KA78
names: Similarity
messages: Belongs to the HsdR family.

105559:NWAT RS03740
gene id: 105559:NWAT_RS03740
uniprot id: D8KBW0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

105559:NWAT RS04840
gene id: 105559:NWAT_RS04840
uniprot id: D8K4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

105559:NWAT RS01010
gene id: 105559:NWAT_RS01010
uniprot id: D8K8W9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

105559:NWAT RS08125
gene id: 105559:NWAT_RS08125
uniprot id: D8K6K9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

105559:NWAT RS02865
gene id: 105559:NWAT_RS02865
uniprot id: D8KB09
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

105559:NWAT RS13800
gene id: 105559:NWAT_RS13800
uniprot id: D8KBE3
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS06020
gene id: 105559:NWAT_RS06020
uniprot id: D8K5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

105559:NWAT RS02215
gene id: 105559:NWAT_RS02215
uniprot id: D8KAA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

105559:NWAT RS07330
gene id: 105559:NWAT_RS07330
uniprot id: D8K667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

105559:NWAT RS12640
gene id: 105559:NWAT_RS12640
uniprot id: D8KA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

105559:NWAT RS14275
gene id: 105559:NWAT_RS14275
uniprot id: D8KC08
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS11240
gene id: 105559:NWAT_RS11240
uniprot id: D8K8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

105559:NWAT RS01180
gene id: 105559:NWAT_RS01180
uniprot id: D8K902
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

105559:NWAT RS00185
gene id: 105559:NWAT_RS00185
uniprot id: D8K832
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

105559:NWAT RS09165
gene id: 105559:NWAT_RS09165
uniprot id: D8K746
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

105559:NWAT RS09055
gene id: 105559:NWAT_RS09055
uniprot id: D8K726
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

105559:NWAT RS02040
gene id: 105559:NWAT_RS02040
uniprot id: D8KA65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02425
gene id: 105559:NWAT_RS02425
uniprot id: D8KAE3
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS11080
gene id: 105559:NWAT_RS11080
uniprot id: D8K8G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

105559:NWAT RS04835
gene id: 105559:NWAT_RS04835
uniprot id: D8K4U7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

105559:NWAT RS07805
gene id: 105559:NWAT_RS07805
uniprot id: D8K6F0
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS00640
gene id: 105559:NWAT_RS00640
uniprot id: D8K8Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

105559:NWAT RS09975
gene id: 105559:NWAT_RS09975
uniprot id: D8K7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

105559:NWAT RS07230
gene id: 105559:NWAT_RS07230
uniprot id: D8K649
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04780
gene id: 105559:NWAT_RS04780
uniprot id: D8K4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

105559:NWAT RS12595
gene id: 105559:NWAT_RS12595
uniprot id: D8KA05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

105559:NWAT RS02005
gene id: 105559:NWAT_RS02005
uniprot id: D8KA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS10230
gene id: 105559:NWAT_RS10230
uniprot id: D8K7P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

105559:NWAT RS11230
gene id: 105559:NWAT_RS11230
uniprot id: D8K8J8
names: Similarity
messages: Belongs to the YfgM family.

105559:NWAT RS10455
gene id: 105559:NWAT_RS10455
uniprot id: D8K7T8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

105559:NWAT RS04570
gene id: 105559:NWAT_RS04570
uniprot id: D8K4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

105559:NWAT RS14885
gene id: 105559:NWAT_RS14885
uniprot id: D8KCB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

105559:NWAT RS00455
gene id: 105559:NWAT_RS00455
uniprot id: D8K880
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

105559:NWAT RS04665
gene id: 105559:NWAT_RS04665
uniprot id: D8K4R3
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02245
gene id: 105559:NWAT_RS02245
uniprot id: D8KAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

105559:NWAT RS02480
gene id: 105559:NWAT_RS02480
uniprot id: D8KAF5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

105559:NWAT RS12855
gene id: 105559:NWAT_RS12855
uniprot id: D8KA52
names: Similarity
messages: Belongs to the TPP enzyme family.

105559:NWAT RS08895
gene id: 105559:NWAT_RS08895
uniprot id: D8K6Z5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

105559:NWAT RS06730
gene id: 105559:NWAT_RS06730
uniprot id: D8K5V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

105559:NWAT RS11355
gene id: 105559:NWAT_RS11355
uniprot id: D8K8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

105559:NWAT RS03400
gene id: 105559:NWAT_RS03400
uniprot id: D8KBP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS02895
gene id: 105559:NWAT_RS02895
uniprot id: D8KB15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

105559:NWAT RS02705
gene id: 105559:NWAT_RS02705
uniprot id: D8KAX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

105559:NWAT RS00245
gene id: 105559:NWAT_RS00245
uniprot id: D8K843
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS03210
gene id: 105559:NWAT_RS03210
uniprot id: D8KB78
names: Similarity
messages: Belongs to the asparagine synthetase family.

105559:NWAT RS10865
gene id: 105559:NWAT_RS10865
uniprot id: D8K8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

105559:NWAT RS02255
gene id: 105559:NWAT_RS02255
uniprot id: D8KAA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

105559:NWAT RS03790
gene id: 105559:NWAT_RS03790
uniprot id: D8KBX0
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10215
gene id: 105559:NWAT_RS10215
uniprot id: D8K7P0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02210
gene id: 105559:NWAT_RS02210
uniprot id: D8KA99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

105559:NWAT RS14135
gene id: 105559:NWAT_RS14135
uniprot id: D8KBK6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

105559:NWAT RS11000
gene id: 105559:NWAT_RS11000
uniprot id: D8K8F0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

105559:NWAT RS09570
gene id: 105559:NWAT_RS09570
uniprot id: D8K7B8
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS05985
gene id: 105559:NWAT_RS05985
uniprot id: D8K5G8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

105559:NWAT RS04700
gene id: 105559:NWAT_RS04700
uniprot id: D8K4S1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS11415
gene id: 105559:NWAT_RS11415
uniprot id: D8K8N5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

105559:NWAT RS10695
gene id: 105559:NWAT_RS10695
uniprot id: D8K7X4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

105559:NWAT RS08485
gene id: 105559:NWAT_RS08485
uniprot id: D8K6S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

105559:NWAT RS01755
gene id: 105559:NWAT_RS01755
uniprot id: D8K9N7
names: Similarity
messages: Belongs to the HisA/HisF family.

105559:NWAT RS00165
gene id: 105559:NWAT_RS00165
uniprot id: D8K828
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

105559:NWAT RS08390
gene id: 105559:NWAT_RS08390
uniprot id: D8K6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

105559:NWAT RS07420
gene id: 105559:NWAT_RS07420
uniprot id: D8K680
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS05005
gene id: 105559:NWAT_RS05005
uniprot id: D8K4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

105559:NWAT RS06970
gene id: 105559:NWAT_RS06970
uniprot id: D8K5Z9
names: Similarity
messages: Belongs to the arginase family.

105559:NWAT RS10140
gene id: 105559:NWAT_RS10140
uniprot id: D8K7M7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

105559:NWAT RS10590
gene id: 105559:NWAT_RS10590
uniprot id: D8K7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

105559:NWAT RS14220
gene id: 105559:NWAT_RS14220
uniprot id: D8KBZ8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

105559:NWAT RS02025
gene id: 105559:NWAT_RS02025
uniprot id: D8KA62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS02435
gene id: 105559:NWAT_RS02435
uniprot id: D8KAE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

105559:NWAT RS01345
gene id: 105559:NWAT_RS01345
uniprot id: D8K9F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

105559:NWAT RS02835
gene id: 105559:NWAT_RS02835
uniprot id: D8KB03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

105559:NWAT RS05550
gene id: 105559:NWAT_RS05550
uniprot id: D8K584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

105559:NWAT RS07180
gene id: 105559:NWAT_RS07180
uniprot id: D8K639
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS03480
gene id: 105559:NWAT_RS03480
uniprot id: D8KBQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS10240
gene id: 105559:NWAT_RS10240
uniprot id: D8K7P5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

105559:NWAT RS03590
gene id: 105559:NWAT_RS03590
uniprot id: D8KBT2
names: Similarity
messages: Belongs to the HSP15 family.

105559:NWAT RS08215
gene id: 105559:NWAT_RS08215
uniprot id: D8K6M8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

105559:NWAT RS07870
gene id: 105559:NWAT_RS07870
uniprot id: D8K6G1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS12115
gene id: 105559:NWAT_RS12115
uniprot id: D8K9D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

105559:NWAT RS02805
gene id: 105559:NWAT_RS02805
uniprot id: D8KAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS10685
gene id: 105559:NWAT_RS10685
uniprot id: D8K7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

105559:NWAT RS05045
gene id: 105559:NWAT_RS05045
uniprot id: D8K4Y8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

105559:NWAT RS09730
gene id: 105559:NWAT_RS09730
uniprot id: D8K7E6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

105559:NWAT RS05590
gene id: 105559:NWAT_RS05590
uniprot id: D8K592
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS10335
gene id: 105559:NWAT_RS10335
uniprot id: D8K7R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

105559:NWAT RS14925
gene id: 105559:NWAT_RS14925
uniprot id: D8K4J2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

105559:NWAT RS10920
gene id: 105559:NWAT_RS10920
uniprot id: D8K8D4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

105559:NWAT RS05785
gene id: 105559:NWAT_RS05785
uniprot id: D8K5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS15225
gene id: 105559:NWAT_RS15225
uniprot id: D8K4Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

105559:NWAT RS05475
gene id: 105559:NWAT_RS05475
uniprot id: D8K570
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

105559:NWAT RS04675
gene id: 105559:NWAT_RS04675
uniprot id: D8K4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

105559:NWAT RS11075
gene id: 105559:NWAT_RS11075
uniprot id: D8K8G6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS03795
gene id: 105559:NWAT_RS03795
uniprot id: D8KBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS12815
gene id: 105559:NWAT_RS12815
uniprot id: D8KA44
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

105559:NWAT RS02510
gene id: 105559:NWAT_RS02510
uniprot id: D8KAG1
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

105559:NWAT RS04790
gene id: 105559:NWAT_RS04790
uniprot id: D8K4T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

105559:NWAT RS02780
gene id: 105559:NWAT_RS02780
uniprot id: D8KAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

105559:NWAT RS00525
gene id: 105559:NWAT_RS00525
uniprot id: D8K895
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

105559:NWAT RS05230
gene id: 105559:NWAT_RS05230
uniprot id: D8K523
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

105559:NWAT RS04030
gene id: 105559:NWAT_RS04030
uniprot id: D8K474
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

105559:NWAT RS15000
gene id: 105559:NWAT_RS15000
uniprot id: D8K4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

105559:NWAT RS10700
gene id: 105559:NWAT_RS10700
uniprot id: D8K7X5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

105559:NWAT RS00505
gene id: 105559:NWAT_RS00505
uniprot id: D8K891
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS08460
gene id: 105559:NWAT_RS08460
uniprot id: D8K6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

105559:NWAT RS12140
gene id: 105559:NWAT_RS12140
uniprot id: D8K9E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

105559:NWAT RS10630
gene id: 105559:NWAT_RS10630
uniprot id: D8K7X4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

105559:NWAT RS05975
gene id: 105559:NWAT_RS05975
uniprot id: D8K5G6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS13445
gene id: 105559:NWAT_RS13445
uniprot id: D8KAV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

105559:NWAT RS00880
gene id: 105559:NWAT_RS00880
uniprot id: D8K8U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS11255
gene id: 105559:NWAT_RS11255
uniprot id: D8K8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

105559:NWAT RS15235
gene id: 105559:NWAT_RS15235
uniprot id: D8K4Q2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

105559:NWAT RS13160
gene id: 105559:NWAT_RS13160
uniprot id: D8KAP6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

105559:NWAT RS15255
gene id: 105559:NWAT_RS15255
uniprot id: D8K4Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS06710
gene id: 105559:NWAT_RS06710
uniprot id: D8K5V3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

105559:NWAT RS02105
gene id: 105559:NWAT_RS02105
uniprot id: D8KA79
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

105559:NWAT RS12150
gene id: 105559:NWAT_RS12150
uniprot id: D8K9E4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

105559:NWAT RS02890
gene id: 105559:NWAT_RS02890
uniprot id: D8KB14
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

105559:NWAT RS01360
gene id: 105559:NWAT_RS01360
uniprot id: D8K9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

105559:NWAT RS03995
gene id: 105559:NWAT_RS03995
uniprot id: D8K467
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

105559:NWAT RS03040
gene id: 105559:NWAT_RS03040
uniprot id: D8KB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

105559:NWAT RS15180
gene id: 105559:NWAT_RS15180
uniprot id: D8K4P1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS02000
gene id: 105559:NWAT_RS02000
uniprot id: D8KA57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

105559:NWAT RS11060
gene id: 105559:NWAT_RS11060
uniprot id: D8K8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

105559:NWAT RS00960
gene id: 105559:NWAT_RS00960
uniprot id: D8K8V9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

105559:NWAT RS13450
gene id: 105559:NWAT_RS13450
uniprot id: D8KAV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS05635
gene id: 105559:NWAT_RS05635
uniprot id: D8K5A1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

105559:NWAT RS03325
gene id: 105559:NWAT_RS03325
uniprot id: D8KBM4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

105559:NWAT RS15165
gene id: 105559:NWAT_RS15165
uniprot id: D8K4N8
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

105559:NWAT RS07310
gene id: 105559:NWAT_RS07310
uniprot id: D8K664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

105559:NWAT RS02270
gene id: 105559:NWAT_RS02270
uniprot id: D8KAB1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

105559:NWAT RS00130
gene id: 105559:NWAT_RS00130
uniprot id: D8K821
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

105559:NWAT RS05275
gene id: 105559:NWAT_RS05275
uniprot id: D8K532
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS00600
gene id: 105559:NWAT_RS00600
uniprot id: D8K8B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

105559:NWAT RS10440
gene id: 105559:NWAT_RS10440
uniprot id: D8K7T5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

105559:NWAT RS09130
gene id: 105559:NWAT_RS09130
uniprot id: D8K739
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

105559:NWAT RS14175
gene id: 105559:NWAT_RS14175
uniprot id: D8KBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

105559:NWAT RS13670
gene id: 105559:NWAT_RS13670
uniprot id: D8KBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

105559:NWAT RS10655
gene id: 105559:NWAT_RS10655
uniprot id: D8K7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

105559:NWAT RS01465
gene id: 105559:NWAT_RS01465
uniprot id: D8K9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

105559:NWAT RS05435
gene id: 105559:NWAT_RS05435
uniprot id: D8K562
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

105559:NWAT RS07970
gene id: 105559:NWAT_RS07970
uniprot id: D8K6H9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

105559:NWAT RS14240
gene id: 105559:NWAT_RS14240
uniprot id: D8KC02
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

105559:NWAT RS02695
gene id: 105559:NWAT_RS02695
uniprot id: D8KAX5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

105559:NWAT RS15030
gene id: 105559:NWAT_RS15030
uniprot id: D8K4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS02120
gene id: 105559:NWAT_RS02120
uniprot id: D8KA81
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

105559:NWAT RS07220
gene id: 105559:NWAT_RS07220
uniprot id: D8K647
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

105559:NWAT RS05715
gene id: 105559:NWAT_RS05715
uniprot id: D8K5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

105559:NWAT RS13285
gene id: 105559:NWAT_RS13285
uniprot id: D8KAS1
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04680
gene id: 105559:NWAT_RS04680
uniprot id: D8K4R6
names: Similarity
messages: Belongs to the UPF0045 family.

105559:NWAT RS02980
gene id: 105559:NWAT_RS02980
uniprot id: D8KB31
names: Subcellular Location Annotation
messages: Cytoplasm

105559:NWAT RS10485
gene id: 105559:NWAT_RS10485
uniprot id: D8K7U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

105559:NWAT RS03015
gene id: 105559:NWAT_RS03015
uniprot id: D8KB38
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS08415
gene id: 105559:NWAT_RS08415
uniprot id: D8K6Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

105559:NWAT RS08380
gene id: 105559:NWAT_RS08380
uniprot id: D8K6Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

105559:NWAT RS04745
gene id: 105559:NWAT_RS04745
uniprot id: D8K4S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

105559:NWAT RS07725
gene id: 105559:NWAT_RS07725
uniprot id: D8K6D7
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

105559:NWAT RS08350
gene id: 105559:NWAT_RS08350
uniprot id: D8K6P6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

105559:NWAT RS02345
gene id: 105559:NWAT_RS02345
uniprot id: D8KAC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

105559:NWAT RS14560
gene id: 105559:NWAT_RS14560
uniprot id: D8KC60
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04565
gene id: 105559:NWAT_RS04565
uniprot id: D8K4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

105559:NWAT RS15265
gene id: 105559:NWAT_RS15265
uniprot id: D8K4Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

105559:NWAT RS05225
gene id: 105559:NWAT_RS05225
uniprot id: D8K522
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

105559:NWAT RS12170
gene id: 105559:NWAT_RS12170
uniprot id: D8K9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

105559:NWAT RS07060
gene id: 105559:NWAT_RS07060
uniprot id: D8K618
names: Similarity
messages: Belongs to the UPF0047 family.

105559:NWAT RS03865
gene id: 105559:NWAT_RS03865
uniprot id: D8KBX9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

105559:NWAT RS07200
gene id: 105559:NWAT_RS07200
uniprot id: D8K643
names: Similarity
messages: Belongs to the fabD family.

105559:NWAT RS02455
gene id: 105559:NWAT_RS02455
uniprot id: D8KAF0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

105559:NWAT RS01955
gene id: 105559:NWAT_RS01955
uniprot id: D8K9S4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

105559:NWAT RS10220
gene id: 105559:NWAT_RS10220
uniprot id: D8K7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

105559:NWAT RS10605
gene id: 105559:NWAT_RS10605
uniprot id: D8K7W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

105559:NWAT RS11540
gene id: 105559:NWAT_RS11540
uniprot id: D8K936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS11180
gene id: 105559:NWAT_RS11180
uniprot id: D8K8I7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

105559:NWAT RS02305
gene id: 105559:NWAT_RS02305
uniprot id: D8KAB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

105559:NWAT RS13260
gene id: 105559:NWAT_RS13260
uniprot id: D8KAR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS02140
gene id: 105559:NWAT_RS02140
uniprot id: D8KA85
names: Similarity
messages: Belongs to the glyoxalase I family.

105559:NWAT RS05610
gene id: 105559:NWAT_RS05610
uniprot id: D8K596
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

105559:NWAT RS14755
gene id: 105559:NWAT_RS14755
uniprot id: D8KC95
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

105559:NWAT RS01305
gene id: 105559:NWAT_RS01305
uniprot id: D8K9E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

105559:NWAT RS00160
gene id: 105559:NWAT_RS00160
uniprot id: D8K827
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

105559:NWAT RS02200
gene id: 105559:NWAT_RS02200
uniprot id: D8KA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

105559:NWAT RS14065
gene id: 105559:NWAT_RS14065
uniprot id: D8KBJ2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

105559:NWAT RS07025
gene id: 105559:NWAT_RS07025
uniprot id: D8K610
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

105559:NWAT RS07380
gene id: 105559:NWAT_RS07380
uniprot id: D8K672
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS04350
gene id: 105559:NWAT_RS04350
uniprot id: D8K4D0
names: Similarity
messages: Belongs to the citrate synthase family.

105559:NWAT RS13365
gene id: 105559:NWAT_RS13365
uniprot id: D8KAT7
names: Similarity
messages: Belongs to the UPF0102 family.

105559:NWAT RS06810
gene id: 105559:NWAT_RS06810
uniprot id: D8K5X2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

105559:NWAT RS05400
gene id: 105559:NWAT_RS05400
uniprot id: D8K553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

105559:NWAT RS10520
gene id: 105559:NWAT_RS10520
uniprot id: D8K7V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

105559:NWAT RS05090
gene id: 105559:NWAT_RS05090
uniprot id: D8K4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

105559:NWAT RS03140
gene id: 105559:NWAT_RS03140
uniprot id: D8KB64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

105559:NWAT RS00610
gene id: 105559:NWAT_RS00610
uniprot id: D8K8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

105559:NWAT RS04345
gene id: 105559:NWAT_RS04345
uniprot id: D8K4C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

105559:NWAT RS04785
gene id: 105559:NWAT_RS04785
uniprot id: D8K4T6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

105559:NWAT RS07345
gene id: 105559:NWAT_RS07345
uniprot id: D8K668
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

105559:NWAT RS05600
gene id: 105559:NWAT_RS05600
uniprot id: D8K594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

105559:NWAT RS11120
gene id: 105559:NWAT_RS11120
uniprot id: D8K8H5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

105559:NWAT RS00825
gene id: 105559:NWAT_RS00825
uniprot id: D8K8T7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

105559:NWAT RS09840
gene id: 105559:NWAT_RS09840
uniprot id: D8K7G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

105559:NWAT RS02560
gene id: 105559:NWAT_RS02560
uniprot id: D8KAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

105559:NWAT RS10765
gene id: 105559:NWAT_RS10765
uniprot id: D8K7Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS11295
gene id: 105559:NWAT_RS11295
uniprot id: D8K8L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

105559:NWAT RS00655
gene id: 105559:NWAT_RS00655
uniprot id: D8K8Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

105559:NWAT RS10975
gene id: 105559:NWAT_RS10975
uniprot id: D8K8E5
names: Similarity
messages: Belongs to the BolA/IbaG family.

105559:NWAT RS03985
gene id: 105559:NWAT_RS03985
uniprot id: D8K465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

105559:NWAT RS14825
gene id: 105559:NWAT_RS14825
uniprot id: D8KCA9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

105559:NWAT RS10210
gene id: 105559:NWAT_RS10210
uniprot id: D8K7N9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

105559:NWAT RS14955
gene id: 105559:NWAT_RS14955
uniprot id: D8K4J7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

105559:NWAT RS06230
gene id: 105559:NWAT_RS06230
uniprot id: D8K5L2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

105559:NWAT RS15250
gene id: 105559:NWAT_RS15250
uniprot id: D8K4Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

105559:NWAT RS01370
gene id: 105559:NWAT_RS01370
uniprot id: D8K9F9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

105559:NWAT RS14880
gene id: 105559:NWAT_RS14880
uniprot id: D8KCB4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

105559:NWAT RS05015
gene id: 105559:NWAT_RS05015
uniprot id: D8K4Y2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

105559:NWAT RS00205
gene id: 105559:NWAT_RS00205
uniprot id: D8K836
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

105559:NWAT RS05895
gene id: 105559:NWAT_RS05895
uniprot id: D8K5F1
names: Similarity
messages: Belongs to the peptidase M1 family.

105559:NWAT RS10860
gene id: 105559:NWAT_RS10860
uniprot id: D8K8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

105559:NWAT RS11730
gene id: 105559:NWAT_RS11730
uniprot id: D8K972
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

105559:NWAT RS14445
gene id: 105559:NWAT_RS14445
uniprot id: D8KC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS10905
gene id: 105559:NWAT_RS10905
uniprot id: D8K8D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

105559:NWAT RS00915
gene id: 105559:NWAT_RS00915
uniprot id: D8K8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

105559:NWAT RS10980
gene id: 105559:NWAT_RS10980
uniprot id: D8K8E6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

105559:NWAT RS09385
gene id: 105559:NWAT_RS09385
uniprot id: D8K784
names: Subcellular Location Annotation
messages: Cell inner membrane

105559:NWAT RS08205
gene id: 105559:NWAT_RS08205
uniprot id: D8K6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

105559:NWAT RS13015
gene id: 105559:NWAT_RS13015
uniprot id: D8KAL6
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS14715
gene id: 105559:NWAT_RS14715
uniprot id: D8KC87
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

105559:NWAT RS02720
gene id: 105559:NWAT_RS02720
uniprot id: D8KAY1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

105559:NWAT RS04005
gene id: 105559:NWAT_RS04005
uniprot id: D8K469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

105559:NWAT RS07240
gene id: 105559:NWAT_RS07240
uniprot id: D8K651
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

105559:NWAT RS01025
gene id: 105559:NWAT_RS01025
uniprot id: D8K8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

105559:NWAT RS09290
gene id: 105559:NWAT_RS09290
uniprot id: D8K767
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

105559:NWAT RS02880
gene id: 105559:NWAT_RS02880
uniprot id: D8KB12
names: Similarity
messages: Belongs to the LOG family.

105559:NWAT RS07900
gene id: 105559:NWAT_RS07900
uniprot id: D8K6G7
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS02645
gene id: 105559:NWAT_RS02645
uniprot id: D8KAI4
names: Similarity
messages: Belongs to the thioredoxin family.

105559:NWAT RS09530
gene id: 105559:NWAT_RS09530
uniprot id: D8K7B0
names: Subcellular Location Annotation
messages: Membrane

105559:NWAT RS00100
gene id: 105559:NWAT_RS00100
uniprot id: D8K815
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

105559:NWAT RS03270
gene id: 105559:NWAT_RS03270
uniprot id: D8KB90
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

105559:NWAT RS06860
gene id: 105559:NWAT_RS06860
uniprot id: D8K5Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

105559:NWAT RS03245
gene id: 105559:NWAT_RS03245
uniprot id: D8KB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

105559:NWAT RS02540
gene id: 105559:NWAT_RS02540
uniprot id: D8KAG6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

105559:NWAT RS12600
gene id: 105559:NWAT_RS12600
uniprot id: D8KA06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

105559:NWAT RS09345
gene id: 105559:NWAT_RS09345
uniprot id: D8K776
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

105559:NWAT RS01695
gene id: 105559:NWAT_RS01695
uniprot id: D8K9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

105559:NWAT RS09420
gene id: 105559:NWAT_RS09420
uniprot id: D8K789
names: Similarity
messages: Belongs to the HicA mRNA interferase family.