1036672:TKWG RS07660
gene id: 1036672:TKWG_RS07660
uniprot id: I3UB19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS07730
gene id: 1036672:TKWG_RS07730
uniprot id: I3UB30
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1036672:TKWG RS10710
gene id: 1036672:TKWG_RS10710
uniprot id: I3UCM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS02170
gene id: 1036672:TKWG_RS02170
uniprot id: I3U824
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS10585
gene id: 1036672:TKWG_RS10585
uniprot id: I3UCK2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1036672:TKWG RS19530
gene id: 1036672:TKWG_RS19530
uniprot id: I3UHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1036672:TKWG RS16580
gene id: 1036672:TKWG_RS16580
uniprot id: I3UFR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1036672:TKWG RS17550
gene id: 1036672:TKWG_RS17550
uniprot id: I3UG93
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS00230
gene id: 1036672:TKWG_RS00230
uniprot id: I3U6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS16990
gene id: 1036672:TKWG_RS16990
uniprot id: I3UFZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1036672:TKWG RS02665
gene id: 1036672:TKWG_RS02665
uniprot id: I3U8B1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1036672:TKWG RS09545
gene id: 1036672:TKWG_RS09545
uniprot id: I3UC07
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1036672:TKWG RS00785
gene id: 1036672:TKWG_RS00785
uniprot id: I3U797
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS13015
gene id: 1036672:TKWG_RS13015
uniprot id: I3UDU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

1036672:TKWG RS18590
gene id: 1036672:TKWG_RS18590
uniprot id: I3UGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS19570
gene id: 1036672:TKWG_RS19570
uniprot id: I3UHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS07680
gene id: 1036672:TKWG_RS07680
uniprot id: I3UB22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS03040
gene id: 1036672:TKWG_RS03040
uniprot id: I3U8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS14115
gene id: 1036672:TKWG_RS14115
uniprot id: I3UEF1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1036672:TKWG RS11150
gene id: 1036672:TKWG_RS11150
uniprot id: I3UCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1036672:TKWG RS14780
gene id: 1036672:TKWG_RS14780
uniprot id: I3UET2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1036672:TKWG RS12000
gene id: 1036672:TKWG_RS12000
uniprot id: I3UDB2
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS16135
gene id: 1036672:TKWG_RS16135
uniprot id: I3UFI2
names: Similarity
messages: Belongs to the citrate synthase family.

1036672:TKWG RS18170
gene id: 1036672:TKWG_RS18170
uniprot id: I3UGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13930
gene id: 1036672:TKWG_RS13930
uniprot id: I3UEB5
names: Similarity
messages: Belongs to the DapA family.

1036672:TKWG RS12650
gene id: 1036672:TKWG_RS12650
uniprot id: I3UDM8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1036672:TKWG RS04585
gene id: 1036672:TKWG_RS04585
uniprot id: I3U9C3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS10180
gene id: 1036672:TKWG_RS10180
uniprot id: I3UCC4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS20585
gene id: 1036672:TKWG_RS20585
uniprot id: I3UHX8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS10985
gene id: 1036672:TKWG_RS10985
uniprot id: I3UCS7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1036672:TKWG RS01635
gene id: 1036672:TKWG_RS01635
uniprot id: I3U7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS20830
gene id: 1036672:TKWG_RS20830
uniprot id: I3UI27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS09930
gene id: 1036672:TKWG_RS09930
uniprot id: I3UC80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1036672:TKWG RS02835
gene id: 1036672:TKWG_RS02835
uniprot id: I3U8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1036672:TKWG RS04510
gene id: 1036672:TKWG_RS04510
uniprot id: I3U9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS08015
gene id: 1036672:TKWG_RS08015
uniprot id: I3UB77
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1036672:TKWG RS12820
gene id: 1036672:TKWG_RS12820
uniprot id: I3UDQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1036672:TKWG RS17540
gene id: 1036672:TKWG_RS17540
uniprot id: I3UG91
names: Similarity
messages: Belongs to the AHA1 family.

1036672:TKWG RS01260
gene id: 1036672:TKWG_RS01260
uniprot id: I3U7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS11090
gene id: 1036672:TKWG_RS11090
uniprot id: I3UCU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS02840
gene id: 1036672:TKWG_RS02840
uniprot id: I3U8E5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1036672:TKWG RS06770
gene id: 1036672:TKWG_RS06770
uniprot id: I3UAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1036672:TKWG RS17865
gene id: 1036672:TKWG_RS17865
uniprot id: I3UGE7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS11615
gene id: 1036672:TKWG_RS11615
uniprot id: I3UD43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1036672:TKWG RS09785
gene id: 1036672:TKWG_RS09785
uniprot id: I3UC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS05140
gene id: 1036672:TKWG_RS05140
uniprot id: I3U9N7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1036672:TKWG RS12680
gene id: 1036672:TKWG_RS12680
uniprot id: I3UDN4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1036672:TKWG RS19515
gene id: 1036672:TKWG_RS19515
uniprot id: I3UHB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1036672:TKWG RS04130
gene id: 1036672:TKWG_RS04130
uniprot id: I3U934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS08300
gene id: 1036672:TKWG_RS08300
uniprot id: I3UBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1036672:TKWG RS14105
gene id: 1036672:TKWG_RS14105
uniprot id: I3UEE8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS08180
gene id: 1036672:TKWG_RS08180
uniprot id: I3UBB0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1036672:TKWG RS15905
gene id: 1036672:TKWG_RS15905
uniprot id: I3UFE1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1036672:TKWG RS20850
gene id: 1036672:TKWG_RS20850
uniprot id: I3UI31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS17710
gene id: 1036672:TKWG_RS17710
uniprot id: I3UGC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS06365
gene id: 1036672:TKWG_RS06365
uniprot id: I3UAD3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1036672:TKWG RS03900
gene id: 1036672:TKWG_RS03900
uniprot id: I3U8Z2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS06590
gene id: 1036672:TKWG_RS06590
uniprot id: I3UAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1036672:TKWG RS05320
gene id: 1036672:TKWG_RS05320
uniprot id: I3U9R9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1036672:TKWG RS04945
gene id: 1036672:TKWG_RS04945
uniprot id: I3U9J9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1036672:TKWG RS15080
gene id: 1036672:TKWG_RS15080
uniprot id: I3UEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1036672:TKWG RS12995
gene id: 1036672:TKWG_RS12995
uniprot id: I3UDU1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1036672:TKWG RS14280
gene id: 1036672:TKWG_RS14280
uniprot id: I3UEI9
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1036672:TKWG RS03345
gene id: 1036672:TKWG_RS03345
uniprot id: I3U8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS25115
gene id: 1036672:TKWG_RS25115
uniprot id: I3UEA7
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS08380
gene id: 1036672:TKWG_RS08380
uniprot id: I3UBE8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1036672:TKWG RS07875
gene id: 1036672:TKWG_RS07875
uniprot id: I3UB55
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1036672:TKWG RS04050
gene id: 1036672:TKWG_RS04050
uniprot id: I3U919
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1036672:TKWG RS21270
gene id: 1036672:TKWG_RS21270
uniprot id: I3UAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1036672:TKWG RS04025
gene id: 1036672:TKWG_RS04025
uniprot id: I3U915
names: Similarity
messages: Belongs to the DapA family.

1036672:TKWG RS02875
gene id: 1036672:TKWG_RS02875
uniprot id: I3U8F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1036672:TKWG RS21575
gene id: 1036672:TKWG_RS21575
uniprot id: I3UD66
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06865
gene id: 1036672:TKWG_RS06865
uniprot id: I3UAM2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS08615
gene id: 1036672:TKWG_RS08615
uniprot id: I3UBJ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1036672:TKWG RS12715
gene id: 1036672:TKWG_RS12715
uniprot id: I3UDN9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1036672:TKWG RS11875
gene id: 1036672:TKWG_RS11875
uniprot id: I3UD90
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1036672:TKWG RS12765
gene id: 1036672:TKWG_RS12765
uniprot id: I3UDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS17645
gene id: 1036672:TKWG_RS17645
uniprot id: I3UGB2
names: Similarity
messages: Belongs to the VgrG protein family.

1036672:TKWG RS06915
gene id: 1036672:TKWG_RS06915
uniprot id: I3UAN2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1036672:TKWG RS11620
gene id: 1036672:TKWG_RS11620
uniprot id: I3UD44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1036672:TKWG RS10440
gene id: 1036672:TKWG_RS10440
uniprot id: I3UCH6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1036672:TKWG RS09415
gene id: 1036672:TKWG_RS09415
uniprot id: I3UBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1036672:TKWG RS09285
gene id: 1036672:TKWG_RS09285
uniprot id: I3UBV6
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS04750
gene id: 1036672:TKWG_RS04750
uniprot id: I3U9F3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1036672:TKWG RS00545
gene id: 1036672:TKWG_RS00545
uniprot id: I3U755
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1036672:TKWG RS19245
gene id: 1036672:TKWG_RS19245
uniprot id: I3UH63
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1036672:TKWG RS08750
gene id: 1036672:TKWG_RS08750
uniprot id: I3UBL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1036672:TKWG RS20315
gene id: 1036672:TKWG_RS20315
uniprot id: I3UHT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1036672:TKWG RS03705
gene id: 1036672:TKWG_RS03705
uniprot id: I3U8V4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS12595
gene id: 1036672:TKWG_RS12595
uniprot id: I3UDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS10730
gene id: 1036672:TKWG_RS10730
uniprot id: I3UCN2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1036672:TKWG RS12140
gene id: 1036672:TKWG_RS12140
uniprot id: I3UDD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1036672:TKWG RS19855
gene id: 1036672:TKWG_RS19855
uniprot id: I3UHI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1036672:TKWG RS15270
gene id: 1036672:TKWG_RS15270
uniprot id: I3UF16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS03935
gene id: 1036672:TKWG_RS03935
uniprot id: I3U900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1036672:TKWG RS09430
gene id: 1036672:TKWG_RS09430
uniprot id: I3UBY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS05165
gene id: 1036672:TKWG_RS05165
uniprot id: I3U9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS17370
gene id: 1036672:TKWG_RS17370
uniprot id: I3UG57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS06330
gene id: 1036672:TKWG_RS06330
uniprot id: I3UAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1036672:TKWG RS02295
gene id: 1036672:TKWG_RS02295
uniprot id: I3U844
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1036672:TKWG RS11675
gene id: 1036672:TKWG_RS11675
uniprot id: I3UD50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1036672:TKWG RS05540
gene id: 1036672:TKWG_RS05540
uniprot id: I3U9W3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1036672:TKWG RS12930
gene id: 1036672:TKWG_RS12930
uniprot id: I3UDT0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1036672:TKWG RS03815
gene id: 1036672:TKWG_RS03815
uniprot id: I3U8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1036672:TKWG RS14975
gene id: 1036672:TKWG_RS14975
uniprot id: I3UEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

1036672:TKWG RS06110
gene id: 1036672:TKWG_RS06110
uniprot id: I3UA79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS13415
gene id: 1036672:TKWG_RS13415
uniprot id: I3UE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS14995
gene id: 1036672:TKWG_RS14995
uniprot id: I3UEX5
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS04505
gene id: 1036672:TKWG_RS04505
uniprot id: I3U9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS14565
gene id: 1036672:TKWG_RS14565
uniprot id: I3UEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS14745
gene id: 1036672:TKWG_RS14745
uniprot id: I3UES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1036672:TKWG RS19490
gene id: 1036672:TKWG_RS19490
uniprot id: I3UHB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1036672:TKWG RS12120
gene id: 1036672:TKWG_RS12120
uniprot id: I3UDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1036672:TKWG RS19870
gene id: 1036672:TKWG_RS19870
uniprot id: I3UHI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1036672:TKWG RS04800
gene id: 1036672:TKWG_RS04800
uniprot id: I3U9G7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1036672:TKWG RS08910
gene id: 1036672:TKWG_RS08910
uniprot id: I3UBN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1036672:TKWG RS00295
gene id: 1036672:TKWG_RS00295
uniprot id: I3U702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS11420
gene id: 1036672:TKWG_RS11420
uniprot id: I3UD02
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1036672:TKWG RS10155
gene id: 1036672:TKWG_RS10155
uniprot id: I3UCC0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1036672:TKWG RS05325
gene id: 1036672:TKWG_RS05325
uniprot id: I3U9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS13475
gene id: 1036672:TKWG_RS13475
uniprot id: I3UE31
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1036672:TKWG RS04580
gene id: 1036672:TKWG_RS04580
uniprot id: I3U9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1036672:TKWG RS15110
gene id: 1036672:TKWG_RS15110
uniprot id: I3UEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1036672:TKWG RS05840
gene id: 1036672:TKWG_RS05840
uniprot id: I3UA26
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1036672:TKWG RS04780
gene id: 1036672:TKWG_RS04780
uniprot id: I3U9F9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS19865
gene id: 1036672:TKWG_RS19865
uniprot id: I3UHI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1036672:TKWG RS00625
gene id: 1036672:TKWG_RS00625
uniprot id: I3U766
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1036672:TKWG RS00815
gene id: 1036672:TKWG_RS00815
uniprot id: I3U7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS01670
gene id: 1036672:TKWG_RS01670
uniprot id: I3U7S8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1036672:TKWG RS04620
gene id: 1036672:TKWG_RS04620
uniprot id: I3U9D1
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06775
gene id: 1036672:TKWG_RS06775
uniprot id: I3UAK6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1036672:TKWG RS17515
gene id: 1036672:TKWG_RS17515
uniprot id: I3UG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS20335
gene id: 1036672:TKWG_RS20335
uniprot id: I3UHT8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1036672:TKWG RS08100
gene id: 1036672:TKWG_RS08100
uniprot id: I3UB93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1036672:TKWG RS07915
gene id: 1036672:TKWG_RS07915
uniprot id: I3UB63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1036672:TKWG RS08245
gene id: 1036672:TKWG_RS08245
uniprot id: I3UBC2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

1036672:TKWG RS01880
gene id: 1036672:TKWG_RS01880
uniprot id: I3U7W7
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS14965
gene id: 1036672:TKWG_RS14965
uniprot id: I3UEX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1036672:TKWG RS03925
gene id: 1036672:TKWG_RS03925
uniprot id: I3U8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1036672:TKWG RS05380
gene id: 1036672:TKWG_RS05380
uniprot id: I3U9T2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS01010
gene id: 1036672:TKWG_RS01010
uniprot id: I3U7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1036672:TKWG RS04765
gene id: 1036672:TKWG_RS04765
uniprot id: I3U9F6
names: Similarity
messages: Belongs to the peptidase A24 family.

1036672:TKWG RS21250
gene id: 1036672:TKWG_RS21250
uniprot id: I3UAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1036672:TKWG RS19085
gene id: 1036672:TKWG_RS19085
uniprot id: I3UH28
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02600
gene id: 1036672:TKWG_RS02600
uniprot id: I3U8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1036672:TKWG RS07755
gene id: 1036672:TKWG_RS07755
uniprot id: I3UB37
names: Subcellular Location Annotation
messages: Cytoplasm

1036672:TKWG RS01730
gene id: 1036672:TKWG_RS01730
uniprot id: I3U7T7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1036672:TKWG RS13805
gene id: 1036672:TKWG_RS13805
uniprot id: I3UE89
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS00170
gene id: 1036672:TKWG_RS00170
uniprot id: I3U6X9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1036672:TKWG RS19080
gene id: 1036672:TKWG_RS19080
uniprot id: I3UH27
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1036672:TKWG RS05830
gene id: 1036672:TKWG_RS05830
uniprot id: I3UA24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1036672:TKWG RS07435
gene id: 1036672:TKWG_RS07435
uniprot id: I3UAX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS10175
gene id: 1036672:TKWG_RS10175
uniprot id: I3UCC3
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS12815
gene id: 1036672:TKWG_RS12815
uniprot id: I3UDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1036672:TKWG RS12355
gene id: 1036672:TKWG_RS12355
uniprot id: I3UDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1036672:TKWG RS09780
gene id: 1036672:TKWG_RS09780
uniprot id: I3UC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS06070
gene id: 1036672:TKWG_RS06070
uniprot id: I3UA71
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS01950
gene id: 1036672:TKWG_RS01950
uniprot id: I3U7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1036672:TKWG RS19750
gene id: 1036672:TKWG_RS19750
uniprot id: I3UHG0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1036672:TKWG RS04570
gene id: 1036672:TKWG_RS04570
uniprot id: I3U9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1036672:TKWG RS18005
gene id: 1036672:TKWG_RS18005
uniprot id: I3UGH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1036672:TKWG RS11385
gene id: 1036672:TKWG_RS11385
uniprot id: I3UCZ6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1036672:TKWG RS14725
gene id: 1036672:TKWG_RS14725
uniprot id: I3UES3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1036672:TKWG RS09385
gene id: 1036672:TKWG_RS09385
uniprot id: I3UBX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1036672:TKWG RS07650
gene id: 1036672:TKWG_RS07650
uniprot id: I3UB17
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1036672:TKWG RS20305
gene id: 1036672:TKWG_RS20305
uniprot id: I3UHT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1036672:TKWG RS08055
gene id: 1036672:TKWG_RS08055
uniprot id: I3UB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1036672:TKWG RS05020
gene id: 1036672:TKWG_RS05020
uniprot id: I3U9L5
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1036672:TKWG RS01830
gene id: 1036672:TKWG_RS01830
uniprot id: I3U7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

1036672:TKWG RS12320
gene id: 1036672:TKWG_RS12320
uniprot id: I3UDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1036672:TKWG RS09260
gene id: 1036672:TKWG_RS09260
uniprot id: I3UBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS19820
gene id: 1036672:TKWG_RS19820
uniprot id: I3UHH3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1036672:TKWG RS16485
gene id: 1036672:TKWG_RS16485
uniprot id: I3UFP6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1036672:TKWG RS06215
gene id: 1036672:TKWG_RS06215
uniprot id: I3UAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS14480
gene id: 1036672:TKWG_RS14480
uniprot id: I3UEM9
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS00010
gene id: 1036672:TKWG_RS00010
uniprot id: I3U6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1036672:TKWG RS17830
gene id: 1036672:TKWG_RS17830
uniprot id: I3UGE0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1036672:TKWG RS02805
gene id: 1036672:TKWG_RS02805
uniprot id: I3U8D9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1036672:TKWG RS08395
gene id: 1036672:TKWG_RS08395
uniprot id: I3UBF1
names: PTM
messages: Binds 1 heme group per subunit.

1036672:TKWG RS05155
gene id: 1036672:TKWG_RS05155
uniprot id: I3U9N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1036672:TKWG RS14205
gene id: 1036672:TKWG_RS14205
uniprot id: I3UEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS11270
gene id: 1036672:TKWG_RS11270
uniprot id: I3UCX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS11780
gene id: 1036672:TKWG_RS11780
uniprot id: I3UD73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS19685
gene id: 1036672:TKWG_RS19685
uniprot id: I3UHE4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS05060
gene id: 1036672:TKWG_RS05060
uniprot id: I3U9M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1036672:TKWG RS17735
gene id: 1036672:TKWG_RS17735
uniprot id: I3UGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS08945
gene id: 1036672:TKWG_RS08945
uniprot id: I3UBP6
names: Similarity
messages: Belongs to the HesB/IscA family.

1036672:TKWG RS18040
gene id: 1036672:TKWG_RS18040
uniprot id: I3UGI0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1036672:TKWG RS02590
gene id: 1036672:TKWG_RS02590
uniprot id: I3U898
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1036672:TKWG RS06565
gene id: 1036672:TKWG_RS06565
uniprot id: I3UAH2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1036672:TKWG RS09855
gene id: 1036672:TKWG_RS09855
uniprot id: I3UC64
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1036672:TKWG RS05745
gene id: 1036672:TKWG_RS05745
uniprot id: I3UA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS11115
gene id: 1036672:TKWG_RS11115
uniprot id: I3UCV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1036672:TKWG RS10635
gene id: 1036672:TKWG_RS10635
uniprot id: I3UCL2
names: Similarity
messages: Belongs to the YciI family.

1036672:TKWG RS18140
gene id: 1036672:TKWG_RS18140
uniprot id: I3UGJ9
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06900
gene id: 1036672:TKWG_RS06900
uniprot id: I3UAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1036672:TKWG RS02205
gene id: 1036672:TKWG_RS02205
uniprot id: I3U831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS07725
gene id: 1036672:TKWG_RS07725
uniprot id: I3UB29
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS16805
gene id: 1036672:TKWG_RS16805
uniprot id: I3UFV0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1036672:TKWG RS04825
gene id: 1036672:TKWG_RS04825
uniprot id: I3U9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS01855
gene id: 1036672:TKWG_RS01855
uniprot id: I3U7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1036672:TKWG RS06835
gene id: 1036672:TKWG_RS06835
uniprot id: I3UAL6
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1036672:TKWG RS01525
gene id: 1036672:TKWG_RS01525
uniprot id: I3U7P6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS05630
gene id: 1036672:TKWG_RS05630
uniprot id: I3U9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1036672:TKWG RS02900
gene id: 1036672:TKWG_RS02900
uniprot id: I3U8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1036672:TKWG RS02020
gene id: 1036672:TKWG_RS02020
uniprot id: I3U7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1036672:TKWG RS05575
gene id: 1036672:TKWG_RS05575
uniprot id: I3U9X1
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1036672:TKWG RS01615
gene id: 1036672:TKWG_RS01615
uniprot id: I3U7R5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1036672:TKWG RS19505
gene id: 1036672:TKWG_RS19505
uniprot id: I3UHB3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1036672:TKWG RS15315
gene id: 1036672:TKWG_RS15315
uniprot id: I3UF23
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1036672:TKWG RS20255
gene id: 1036672:TKWG_RS20255
uniprot id: I3UHS2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1036672:TKWG RS19485
gene id: 1036672:TKWG_RS19485
uniprot id: I3UHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1036672:TKWG RS05130
gene id: 1036672:TKWG_RS05130
uniprot id: I3U9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1036672:TKWG RS15475
gene id: 1036672:TKWG_RS15475
uniprot id: I3UF53
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS07245
gene id: 1036672:TKWG_RS07245
uniprot id: I3UAU4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS11785
gene id: 1036672:TKWG_RS11785
uniprot id: I3UD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS16425
gene id: 1036672:TKWG_RS16425
uniprot id: I3UFP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1036672:TKWG RS18975
gene id: 1036672:TKWG_RS18975
uniprot id: I3UH08
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1036672:TKWG RS02390
gene id: 1036672:TKWG_RS02390
uniprot id: I3U860
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1036672:TKWG RS15860
gene id: 1036672:TKWG_RS15860
uniprot id: I3UFC7
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1036672:TKWG RS12400
gene id: 1036672:TKWG_RS12400
uniprot id: I3UDI7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS03910
gene id: 1036672:TKWG_RS03910
uniprot id: I3U8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1036672:TKWG RS05810
gene id: 1036672:TKWG_RS05810
uniprot id: I3UA20
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1036672:TKWG RS08940
gene id: 1036672:TKWG_RS08940
uniprot id: I3UBP5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1036672:TKWG RS18150
gene id: 1036672:TKWG_RS18150
uniprot id: I3UGK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1036672:TKWG RS03675
gene id: 1036672:TKWG_RS03675
uniprot id: I3U8U8
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS15100
gene id: 1036672:TKWG_RS15100
uniprot id: I3UEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1036672:TKWG RS04330
gene id: 1036672:TKWG_RS04330
uniprot id: I3U975
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS09495
gene id: 1036672:TKWG_RS09495
uniprot id: I3UC00
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1036672:TKWG RS01005
gene id: 1036672:TKWG_RS01005
uniprot id: I3U7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1036672:TKWG RS17225
gene id: 1036672:TKWG_RS17225
uniprot id: I3UG31
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS00935
gene id: 1036672:TKWG_RS00935
uniprot id: I3U7C7
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1036672:TKWG RS15990
gene id: 1036672:TKWG_RS15990
uniprot id: I3UFF6
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1036672:TKWG RS09850
gene id: 1036672:TKWG_RS09850
uniprot id: I3UC63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1036672:TKWG RS06075
gene id: 1036672:TKWG_RS06075
uniprot id: I3UA72
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS21910
gene id: 1036672:TKWG_RS21910
uniprot id: I3UG87
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS14875
gene id: 1036672:TKWG_RS14875
uniprot id: I3UEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1036672:TKWG RS19715
gene id: 1036672:TKWG_RS19715
uniprot id: I3UHF1
names: Similarity
messages: Belongs to the AHA1 family.

1036672:TKWG RS13615
gene id: 1036672:TKWG_RS13615
uniprot id: I3UE53
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS12750
gene id: 1036672:TKWG_RS12750
uniprot id: I3UDP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS06435
gene id: 1036672:TKWG_RS06435
uniprot id: I3UAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1036672:TKWG RS18390
gene id: 1036672:TKWG_RS18390
uniprot id: I3UGP9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1036672:TKWG RS09410
gene id: 1036672:TKWG_RS09410
uniprot id: I3UBY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS08025
gene id: 1036672:TKWG_RS08025
uniprot id: I3UB79
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1036672:TKWG RS13915
gene id: 1036672:TKWG_RS13915
uniprot id: I3UEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS04905
gene id: 1036672:TKWG_RS04905
uniprot id: I3U9J0
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1036672:TKWG RS09810
gene id: 1036672:TKWG_RS09810
uniprot id: I3UC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1036672:TKWG RS03570
gene id: 1036672:TKWG_RS03570
uniprot id: I3U8S7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1036672:TKWG RS05505
gene id: 1036672:TKWG_RS05505
uniprot id: I3U9V7
names: Similarity
messages: Belongs to the universal stress protein A family.

1036672:TKWG RS04975
gene id: 1036672:TKWG_RS04975
uniprot id: I3U9K4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS15515
gene id: 1036672:TKWG_RS15515
uniprot id: I3UF62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1036672:TKWG RS08775
gene id: 1036672:TKWG_RS08775
uniprot id: I3UBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1036672:TKWG RS14650
gene id: 1036672:TKWG_RS14650
uniprot id: I3UER2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1036672:TKWG RS07635
gene id: 1036672:TKWG_RS07635
uniprot id: I3UB14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS03820
gene id: 1036672:TKWG_RS03820
uniprot id: I3U8X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1036672:TKWG RS05670
gene id: 1036672:TKWG_RS05670
uniprot id: I3U9Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1036672:TKWG RS03265
gene id: 1036672:TKWG_RS03265
uniprot id: I3U8M7
names: Similarity
messages: Belongs to the UPF0423 family.

1036672:TKWG RS07620
gene id: 1036672:TKWG_RS07620
uniprot id: I3UB11
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

1036672:TKWG RS14220
gene id: 1036672:TKWG_RS14220
uniprot id: I3UEH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS19770
gene id: 1036672:TKWG_RS19770
uniprot id: I3UHG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS09915
gene id: 1036672:TKWG_RS09915
uniprot id: I3UC77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1036672:TKWG RS17340
gene id: 1036672:TKWG_RS17340
uniprot id: I3UG52
names: Similarity
messages: Belongs to the VgrG protein family.

1036672:TKWG RS00175
gene id: 1036672:TKWG_RS00175
uniprot id: I3U6Y0
names: Similarity
messages: Belongs to the TPP enzyme family.

1036672:TKWG RS02565
gene id: 1036672:TKWG_RS02565
uniprot id: I3U892
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1036672:TKWG RS09435
gene id: 1036672:TKWG_RS09435
uniprot id: I3UBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1036672:TKWG RS12805
gene id: 1036672:TKWG_RS12805
uniprot id: I3UDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1036672:TKWG RS06735
gene id: 1036672:TKWG_RS06735
uniprot id: I3UAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1036672:TKWG RS01985
gene id: 1036672:TKWG_RS01985
uniprot id: I3U7Y9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1036672:TKWG RS02235
gene id: 1036672:TKWG_RS02235
uniprot id: I3U834
names: Similarity
messages: Belongs to the class-I fumarase family.

1036672:TKWG RS21380
gene id: 1036672:TKWG_RS21380
uniprot id: I3UB39
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1036672:TKWG RS08305
gene id: 1036672:TKWG_RS08305
uniprot id: I3UBD4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1036672:TKWG RS01080
gene id: 1036672:TKWG_RS01080
uniprot id: I3U7F7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1036672:TKWG RS05645
gene id: 1036672:TKWG_RS05645
uniprot id: I3U9Y7
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS08110
gene id: 1036672:TKWG_RS08110
uniprot id: I3UB94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS10890
gene id: 1036672:TKWG_RS10890
uniprot id: I3UCQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1036672:TKWG RS18660
gene id: 1036672:TKWG_RS18660
uniprot id: I3UGU8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS13530
gene id: 1036672:TKWG_RS13530
uniprot id: I3UE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1036672:TKWG RS20330
gene id: 1036672:TKWG_RS20330
uniprot id: I3UHT7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1036672:TKWG RS07670
gene id: 1036672:TKWG_RS07670
uniprot id: I3UB20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS19450
gene id: 1036672:TKWG_RS19450
uniprot id: I3UHA1
names: Similarity
messages: Belongs to the CutA family.

1036672:TKWG RS13375
gene id: 1036672:TKWG_RS13375
uniprot id: I3UE13
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1036672:TKWG RS08280
gene id: 1036672:TKWG_RS08280
uniprot id: I3UBC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1036672:TKWG RS07325
gene id: 1036672:TKWG_RS07325
uniprot id: I3UAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1036672:TKWG RS20005
gene id: 1036672:TKWG_RS20005
uniprot id: I3UHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1036672:TKWG RS11145
gene id: 1036672:TKWG_RS11145
uniprot id: I3UCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS20440
gene id: 1036672:TKWG_RS20440
uniprot id: I3UHV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1036672:TKWG RS06845
gene id: 1036672:TKWG_RS06845
uniprot id: I3UAL8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1036672:TKWG RS21320
gene id: 1036672:TKWG_RS21320
uniprot id: I3UAR0
names: Similarity
messages: Belongs to the TonB-dependent receptor family.

1036672:TKWG RS14285
gene id: 1036672:TKWG_RS14285
uniprot id: I3UEJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1036672:TKWG RS09185
gene id: 1036672:TKWG_RS09185
uniprot id: I3UBT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1036672:TKWG RS08255
gene id: 1036672:TKWG_RS08255
uniprot id: I3UBC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1036672:TKWG RS12690
gene id: 1036672:TKWG_RS12690
uniprot id: I3UDN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1036672:TKWG RS13890
gene id: 1036672:TKWG_RS13890
uniprot id: I3UEA6
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1036672:TKWG RS19220
gene id: 1036672:TKWG_RS19220
uniprot id: I3UH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS15305
gene id: 1036672:TKWG_RS15305
uniprot id: I3UF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

1036672:TKWG RS04405
gene id: 1036672:TKWG_RS04405
uniprot id: I3U987
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS09400
gene id: 1036672:TKWG_RS09400
uniprot id: I3UBY1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1036672:TKWG RS08225
gene id: 1036672:TKWG_RS08225
uniprot id: I3UBB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1036672:TKWG RS00275
gene id: 1036672:TKWG_RS00275
uniprot id: I3U6Z8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS19740
gene id: 1036672:TKWG_RS19740
uniprot id: I3UHF8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1036672:TKWG RS13730
gene id: 1036672:TKWG_RS13730
uniprot id: I3UE73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS02570
gene id: 1036672:TKWG_RS02570
uniprot id: I3U893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1036672:TKWG RS07355
gene id: 1036672:TKWG_RS07355
uniprot id: I3UAW2
names: Similarity
messages: Belongs to the SCO1/2 family.

1036672:TKWG RS12220
gene id: 1036672:TKWG_RS12220
uniprot id: I3UDF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1036672:TKWG RS16950
gene id: 1036672:TKWG_RS16950
uniprot id: I3UFY2
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS18490
gene id: 1036672:TKWG_RS18490
uniprot id: I3UGR5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1036672:TKWG RS20595
gene id: 1036672:TKWG_RS20595
uniprot id: I3UHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS14055
gene id: 1036672:TKWG_RS14055
uniprot id: I3UED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1036672:TKWG RS19140
gene id: 1036672:TKWG_RS19140
uniprot id: I3UH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13795
gene id: 1036672:TKWG_RS13795
uniprot id: I3UE87
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1036672:TKWG RS07880
gene id: 1036672:TKWG_RS07880
uniprot id: I3UB56
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1036672:TKWG RS15950
gene id: 1036672:TKWG_RS15950
uniprot id: I3UFF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS04990
gene id: 1036672:TKWG_RS04990
uniprot id: I3U9K7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1036672:TKWG RS05135
gene id: 1036672:TKWG_RS05135
uniprot id: I3U9N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1036672:TKWG RS12170
gene id: 1036672:TKWG_RS12170
uniprot id: I3UDE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1036672:TKWG RS05790
gene id: 1036672:TKWG_RS05790
uniprot id: I3UA17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS19880
gene id: 1036672:TKWG_RS19880
uniprot id: I3UHI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1036672:TKWG RS06425
gene id: 1036672:TKWG_RS06425
uniprot id: I3UAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1036672:TKWG RS00960
gene id: 1036672:TKWG_RS00960
uniprot id: I3U7D2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS14820
gene id: 1036672:TKWG_RS14820
uniprot id: I3UEU0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1036672:TKWG RS19390
gene id: 1036672:TKWG_RS19390
uniprot id: I3UH89
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1036672:TKWG RS05815
gene id: 1036672:TKWG_RS05815
uniprot id: I3UA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS05775
gene id: 1036672:TKWG_RS05775
uniprot id: I3UA13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1036672:TKWG RS03875
gene id: 1036672:TKWG_RS03875
uniprot id: I3U8Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1036672:TKWG RS13025
gene id: 1036672:TKWG_RS13025
uniprot id: I3UDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1036672:TKWG RS06660
gene id: 1036672:TKWG_RS06660
uniprot id: I3UAI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1036672:TKWG RS20375
gene id: 1036672:TKWG_RS20375
uniprot id: I3UHU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1036672:TKWG RS00120
gene id: 1036672:TKWG_RS00120
uniprot id: I3U6X1
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS12720
gene id: 1036672:TKWG_RS12720
uniprot id: I3UDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1036672:TKWG RS09925
gene id: 1036672:TKWG_RS09925
uniprot id: I3UC79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1036672:TKWG RS14425
gene id: 1036672:TKWG_RS14425
uniprot id: I3UEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1036672:TKWG RS13510
gene id: 1036672:TKWG_RS13510
uniprot id: I3UE37
names: Similarity
messages: Belongs to the UPF0234 family.

1036672:TKWG RS17220
gene id: 1036672:TKWG_RS17220
uniprot id: I3UG30
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1036672:TKWG RS12760
gene id: 1036672:TKWG_RS12760
uniprot id: I3UDP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS06010
gene id: 1036672:TKWG_RS06010
uniprot id: I3UA57
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS09945
gene id: 1036672:TKWG_RS09945
uniprot id: I3UC83
names: Similarity
messages: Belongs to the IMPACT family.

1036672:TKWG RS10990
gene id: 1036672:TKWG_RS10990
uniprot id: I3UCS8
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1036672:TKWG RS10495
gene id: 1036672:TKWG_RS10495
uniprot id: I3UCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS05865
gene id: 1036672:TKWG_RS05865
uniprot id: I3UA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1036672:TKWG RS19385
gene id: 1036672:TKWG_RS19385
uniprot id: I3UH88
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1036672:TKWG RS21230
gene id: 1036672:TKWG_RS21230
uniprot id: I3UA70
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS20580
gene id: 1036672:TKWG_RS20580
uniprot id: I3UHX7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1036672:TKWG RS09890
gene id: 1036672:TKWG_RS09890
uniprot id: I3UC71
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1036672:TKWG RS13030
gene id: 1036672:TKWG_RS13030
uniprot id: I3UDU8
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

1036672:TKWG RS08560
gene id: 1036672:TKWG_RS08560
uniprot id: I3UBI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS20840
gene id: 1036672:TKWG_RS20840
uniprot id: I3UI29
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS07225
gene id: 1036672:TKWG_RS07225
uniprot id: I3UAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS08845
gene id: 1036672:TKWG_RS08845
uniprot id: I3UBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1036672:TKWG RS19850
gene id: 1036672:TKWG_RS19850
uniprot id: I3UHH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1036672:TKWG RS02055
gene id: 1036672:TKWG_RS02055
uniprot id: I3U802
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1036672:TKWG RS00940
gene id: 1036672:TKWG_RS00940
uniprot id: I3U7C8
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS16320
gene id: 1036672:TKWG_RS16320
uniprot id: I3UFM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS17520
gene id: 1036672:TKWG_RS17520
uniprot id: I3UG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS19690
gene id: 1036672:TKWG_RS19690
uniprot id: I3UHE5
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS16695
gene id: 1036672:TKWG_RS16695
uniprot id: I3UFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1036672:TKWG RS06890
gene id: 1036672:TKWG_RS06890
uniprot id: I3UAM6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1036672:TKWG RS07745
gene id: 1036672:TKWG_RS07745
uniprot id: I3UB34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS05880
gene id: 1036672:TKWG_RS05880
uniprot id: I3UA35
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1036672:TKWG RS16715
gene id: 1036672:TKWG_RS16715
uniprot id: I3UFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1036672:TKWG RS10480
gene id: 1036672:TKWG_RS10480
uniprot id: I3UCI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS13775
gene id: 1036672:TKWG_RS13775
uniprot id: I3UE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1036672:TKWG RS16090
gene id: 1036672:TKWG_RS16090
uniprot id: I3UFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS06670
gene id: 1036672:TKWG_RS06670
uniprot id: I3UAJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1036672:TKWG RS19235
gene id: 1036672:TKWG_RS19235
uniprot id: I3UH61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS01905
gene id: 1036672:TKWG_RS01905
uniprot id: I3U7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1036672:TKWG RS14040
gene id: 1036672:TKWG_RS14040
uniprot id: I3UED5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1036672:TKWG RS19730
gene id: 1036672:TKWG_RS19730
uniprot id: I3UHF6
names: Similarity
messages: Belongs to the hyi family.

1036672:TKWG RS02965
gene id: 1036672:TKWG_RS02965
uniprot id: I3U8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS17595
gene id: 1036672:TKWG_RS17595
uniprot id: I3UGA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08915
gene id: 1036672:TKWG_RS08915
uniprot id: I3UBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1036672:TKWG RS00365
gene id: 1036672:TKWG_RS00365
uniprot id: I3U719
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS15215
gene id: 1036672:TKWG_RS15215
uniprot id: I3UF10
names: Similarity
messages: Belongs to the TonB-dependent receptor family.

1036672:TKWG RS14430
gene id: 1036672:TKWG_RS14430
uniprot id: I3UEM1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1036672:TKWG RS09825
gene id: 1036672:TKWG_RS09825
uniprot id: I3UC59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS00130
gene id: 1036672:TKWG_RS00130
uniprot id: I3U6X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS06630
gene id: 1036672:TKWG_RS06630
uniprot id: I3UAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1036672:TKWG RS10085
gene id: 1036672:TKWG_RS10085
uniprot id: I3UCA9
names: Similarity
messages: Belongs to the Gfa family.

1036672:TKWG RS04890
gene id: 1036672:TKWG_RS04890
uniprot id: I3U9I5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1036672:TKWG RS06210
gene id: 1036672:TKWG_RS06210
uniprot id: I3UA99
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS16190
gene id: 1036672:TKWG_RS16190
uniprot id: I3UFJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS01900
gene id: 1036672:TKWG_RS01900
uniprot id: I3U7X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1036672:TKWG RS03005
gene id: 1036672:TKWG_RS03005
uniprot id: I3U8H6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS03830
gene id: 1036672:TKWG_RS03830
uniprot id: I3U8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS05570
gene id: 1036672:TKWG_RS05570
uniprot id: I3U9X0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1036672:TKWG RS18645
gene id: 1036672:TKWG_RS18645
uniprot id: I3UGU4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS04940
gene id: 1036672:TKWG_RS04940
uniprot id: I3U9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1036672:TKWG RS11925
gene id: 1036672:TKWG_RS11925
uniprot id: I3UD99
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02800
gene id: 1036672:TKWG_RS02800
uniprot id: I3U8D8
names: Subcellular Location Annotation
messages: Mitochondrion

1036672:TKWG RS04460
gene id: 1036672:TKWG_RS04460
uniprot id: I3U9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS17365
gene id: 1036672:TKWG_RS17365
uniprot id: I3UG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS17620
gene id: 1036672:TKWG_RS17620
uniprot id: I3UGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS09485
gene id: 1036672:TKWG_RS09485
uniprot id: I3UBZ8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1036672:TKWG RS14615
gene id: 1036672:TKWG_RS14615
uniprot id: I3UEQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS09490
gene id: 1036672:TKWG_RS09490
uniprot id: I3UBZ9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1036672:TKWG RS10330
gene id: 1036672:TKWG_RS10330
uniprot id: I3UCF2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1036672:TKWG RS06065
gene id: 1036672:TKWG_RS06065
uniprot id: I3UA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS21750
gene id: 1036672:TKWG_RS21750
uniprot id: I3UEL0
names: Similarity
messages: Belongs to the ModE family.

1036672:TKWG RS07430
gene id: 1036672:TKWG_RS07430
uniprot id: I3UAX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS02740
gene id: 1036672:TKWG_RS02740
uniprot id: I3U8C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1036672:TKWG RS15075
gene id: 1036672:TKWG_RS15075
uniprot id: I3UEY5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1036672:TKWG RS03915
gene id: 1036672:TKWG_RS03915
uniprot id: I3U8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1036672:TKWG RS09425
gene id: 1036672:TKWG_RS09425
uniprot id: I3UBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1036672:TKWG RS19270
gene id: 1036672:TKWG_RS19270
uniprot id: I3UH68
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1036672:TKWG RS03320
gene id: 1036672:TKWG_RS03320
uniprot id: I3U8N6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS13665
gene id: 1036672:TKWG_RS13665
uniprot id: I3UE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS02670
gene id: 1036672:TKWG_RS02670
uniprot id: I3U8B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1036672:TKWG RS13705
gene id: 1036672:TKWG_RS13705
uniprot id: I3UE69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS11155
gene id: 1036672:TKWG_RS11155
uniprot id: I3UCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Periplasm

1036672:TKWG RS11705
gene id: 1036672:TKWG_RS11705
uniprot id: I3UD54
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1036672:TKWG RS07500
gene id: 1036672:TKWG_RS07500
uniprot id: I3UAY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS00165
gene id: 1036672:TKWG_RS00165
uniprot id: I3U6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS02450
gene id: 1036672:TKWG_RS02450
uniprot id: I3U871
names: Similarity
messages: Belongs to the SCO1/2 family.

1036672:TKWG RS08440
gene id: 1036672:TKWG_RS08440
uniprot id: I3UBG0
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1036672:TKWG RS05935
gene id: 1036672:TKWG_RS05935
uniprot id: I3UA45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1036672:TKWG RS15610
gene id: 1036672:TKWG_RS15610
uniprot id: I3UF81
names: Similarity
messages: Belongs to the ArsC family.

1036672:TKWG RS20030
gene id: 1036672:TKWG_RS20030
uniprot id: I3UHL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1036672:TKWG RS01235
gene id: 1036672:TKWG_RS01235
uniprot id: I3U7J0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS09675
gene id: 1036672:TKWG_RS09675
uniprot id: I3UC30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS07640
gene id: 1036672:TKWG_RS07640
uniprot id: I3UB15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS20460
gene id: 1036672:TKWG_RS20460
uniprot id: I3UHV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1036672:TKWG RS12980
gene id: 1036672:TKWG_RS12980
uniprot id: I3UDT8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1036672:TKWG RS02935
gene id: 1036672:TKWG_RS02935
uniprot id: I3U8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

1036672:TKWG RS09105
gene id: 1036672:TKWG_RS09105
uniprot id: I3UBS4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02180
gene id: 1036672:TKWG_RS02180
uniprot id: I3U826
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS13445
gene id: 1036672:TKWG_RS13445
uniprot id: I3UE23
names: Similarity
messages: Belongs to the citrate synthase family.

1036672:TKWG RS01365
gene id: 1036672:TKWG_RS01365
uniprot id: I3U7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS12555
gene id: 1036672:TKWG_RS12555
uniprot id: I3UDL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS11085
gene id: 1036672:TKWG_RS11085
uniprot id: I3UCU5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1036672:TKWG RS09205
gene id: 1036672:TKWG_RS09205
uniprot id: I3UBU3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1036672:TKWG RS01665
gene id: 1036672:TKWG_RS01665
uniprot id: I3U7S7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1036672:TKWG RS13450
gene id: 1036672:TKWG_RS13450
uniprot id: I3UE24
names: Similarity
messages: Belongs to the PrpD family.

1036672:TKWG RS01140
gene id: 1036672:TKWG_RS01140
uniprot id: I3U7H0
names: Similarity
messages: Belongs to the class-I fumarase family.

1036672:TKWG RS01425
gene id: 1036672:TKWG_RS01425
uniprot id: I3U7M9
names: Similarity
messages: Belongs to the VgrG protein family.

1036672:TKWG RS12175
gene id: 1036672:TKWG_RS12175
uniprot id: I3UDE1
names: Subcellular Location Annotation
messages: Cytoplasm

1036672:TKWG RS08570
gene id: 1036672:TKWG_RS08570
uniprot id: I3UBI3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1036672:TKWG RS15225
gene id: 1036672:TKWG_RS15225
uniprot id: I3UF12
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS01415
gene id: 1036672:TKWG_RS01415
uniprot id: I3U7M7
names: Similarity
messages: Belongs to the VgrG protein family.

1036672:TKWG RS06220
gene id: 1036672:TKWG_RS06220
uniprot id: I3UAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS00215
gene id: 1036672:TKWG_RS00215
uniprot id: I3U6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS01875
gene id: 1036672:TKWG_RS01875
uniprot id: I3U7W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1036672:TKWG RS19535
gene id: 1036672:TKWG_RS19535
uniprot id: I3UHB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1036672:TKWG RS19890
gene id: 1036672:TKWG_RS19890
uniprot id: I3UHI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1036672:TKWG RS19285
gene id: 1036672:TKWG_RS19285
uniprot id: I3UH71
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1036672:TKWG RS12015
gene id: 1036672:TKWG_RS12015
uniprot id: I3UDB5
names: Similarity
messages: Belongs to the UPF0178 family.

1036672:TKWG RS04665
gene id: 1036672:TKWG_RS04665
uniprot id: I3U9D8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1036672:TKWG RS03980
gene id: 1036672:TKWG_RS03980
uniprot id: I3U907
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1036672:TKWG RS14335
gene id: 1036672:TKWG_RS14335
uniprot id: I3UEK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08520
gene id: 1036672:TKWG_RS08520
uniprot id: I3UBH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1036672:TKWG RS18890
gene id: 1036672:TKWG_RS18890
uniprot id: I3UGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS18325
gene id: 1036672:TKWG_RS18325
uniprot id: I3UGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10625
gene id: 1036672:TKWG_RS10625
uniprot id: I3UCL0
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS05905
gene id: 1036672:TKWG_RS05905
uniprot id: I3UA40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1036672:TKWG RS02255
gene id: 1036672:TKWG_RS02255
uniprot id: I3U838
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1036672:TKWG RS04180
gene id: 1036672:TKWG_RS04180
uniprot id: I3U947
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS04695
gene id: 1036672:TKWG_RS04695
uniprot id: I3U9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1036672:TKWG RS09465
gene id: 1036672:TKWG_RS09465
uniprot id: I3UBZ4
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1036672:TKWG RS24310
gene id: 1036672:TKWG_RS24310
uniprot id: I3U7H7
names: Similarity
messages: Belongs to the TonB-dependent receptor family.

1036672:TKWG RS17950
gene id: 1036672:TKWG_RS17950
uniprot id: I3UGG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1036672:TKWG RS20645
gene id: 1036672:TKWG_RS20645
uniprot id: I3UHZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1036672:TKWG RS15410
gene id: 1036672:TKWG_RS15410
uniprot id: I3UF39
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1036672:TKWG RS17800
gene id: 1036672:TKWG_RS17800
uniprot id: I3UGD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1036672:TKWG RS14025
gene id: 1036672:TKWG_RS14025
uniprot id: I3UED3
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS14245
gene id: 1036672:TKWG_RS14245
uniprot id: I3UEI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1036672:TKWG RS02535
gene id: 1036672:TKWG_RS02535
uniprot id: I3U886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS02345
gene id: 1036672:TKWG_RS02345
uniprot id: I3U853
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS20825
gene id: 1036672:TKWG_RS20825
uniprot id: I3UI26
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1036672:TKWG RS16220
gene id: 1036672:TKWG_RS16220
uniprot id: I3UFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1036672:TKWG RS15975
gene id: 1036672:TKWG_RS15975
uniprot id: I3UFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS08545
gene id: 1036672:TKWG_RS08545
uniprot id: I3UBH9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1036672:TKWG RS12615
gene id: 1036672:TKWG_RS12615
uniprot id: I3UDM0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1036672:TKWG RS03685
gene id: 1036672:TKWG_RS03685
uniprot id: I3U8V0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1036672:TKWG RS20210
gene id: 1036672:TKWG_RS20210
uniprot id: I3UHR1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1036672:TKWG RS18885
gene id: 1036672:TKWG_RS18885
uniprot id: I3UGZ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS00530
gene id: 1036672:TKWG_RS00530
uniprot id: I3U752
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1036672:TKWG RS18785
gene id: 1036672:TKWG_RS18785
uniprot id: I3UGX0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS07605
gene id: 1036672:TKWG_RS07605
uniprot id: I3UB09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1036672:TKWG RS00035
gene id: 1036672:TKWG_RS00035
uniprot id: I3U6V6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS08935
gene id: 1036672:TKWG_RS08935
uniprot id: I3UBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1036672:TKWG RS00525
gene id: 1036672:TKWG_RS00525
uniprot id: I3U751
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1036672:TKWG RS10300
gene id: 1036672:TKWG_RS10300
uniprot id: I3UCE7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1036672:TKWG RS02465
gene id: 1036672:TKWG_RS02465
uniprot id: I3U873
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1036672:TKWG RS04225
gene id: 1036672:TKWG_RS04225
uniprot id: I3U955
names: Similarity
messages: Belongs to the class-I fumarase family.

1036672:TKWG RS19125
gene id: 1036672:TKWG_RS19125
uniprot id: I3UH37
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1036672:TKWG RS18100
gene id: 1036672:TKWG_RS18100
uniprot id: I3UGJ1
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02580
gene id: 1036672:TKWG_RS02580
uniprot id: I3U896
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS03635
gene id: 1036672:TKWG_RS03635
uniprot id: I3U8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1036672:TKWG RS02200
gene id: 1036672:TKWG_RS02200
uniprot id: I3U830
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS05625
gene id: 1036672:TKWG_RS05625
uniprot id: I3U9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1036672:TKWG RS04725
gene id: 1036672:TKWG_RS04725
uniprot id: I3U9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS11890
gene id: 1036672:TKWG_RS11890
uniprot id: I3UD93
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1036672:TKWG RS05035
gene id: 1036672:TKWG_RS05035
uniprot id: I3U9L7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS00205
gene id: 1036672:TKWG_RS00205
uniprot id: I3U6Y5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS18780
gene id: 1036672:TKWG_RS18780
uniprot id: I3UGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS12570
gene id: 1036672:TKWG_RS12570
uniprot id: I3UDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1036672:TKWG RS20320
gene id: 1036672:TKWG_RS20320
uniprot id: I3UHT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1036672:TKWG RS20655
gene id: 1036672:TKWG_RS20655
uniprot id: I3UHZ2
names: Similarity
messages: Belongs to the GSP E family.

1036672:TKWG RS10115
gene id: 1036672:TKWG_RS10115
uniprot id: I3UCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS14470
gene id: 1036672:TKWG_RS14470
uniprot id: I3UEM7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1036672:TKWG RS18010
gene id: 1036672:TKWG_RS18010
uniprot id: I3UGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS02615
gene id: 1036672:TKWG_RS02615
uniprot id: I3U8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1036672:TKWG RS20010
gene id: 1036672:TKWG_RS20010
uniprot id: I3UHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS04970
gene id: 1036672:TKWG_RS04970
uniprot id: I3U9K3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS19555
gene id: 1036672:TKWG_RS19555
uniprot id: I3UHC2
names: Similarity
messages: Belongs to the MipA/OmpV family.

1036672:TKWG RS16465
gene id: 1036672:TKWG_RS16465
uniprot id: I3UFP4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1036672:TKWG RS19810
gene id: 1036672:TKWG_RS19810
uniprot id: I3UHH1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1036672:TKWG RS00495
gene id: 1036672:TKWG_RS00495
uniprot id: I3U744
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS06205
gene id: 1036672:TKWG_RS06205
uniprot id: I3UA98
names: Subunit
messages: Homodimer.

1036672:TKWG RS11345
gene id: 1036672:TKWG_RS11345
uniprot id: I3UCY8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1036672:TKWG RS06410
gene id: 1036672:TKWG_RS06410
uniprot id: I3UAE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1036672:TKWG RS02050
gene id: 1036672:TKWG_RS02050
uniprot id: I3U801
names: Similarity
messages: Belongs to the HSP15 family.

1036672:TKWG RS02680
gene id: 1036672:TKWG_RS02680
uniprot id: I3U8B4
names: Similarity
messages: Belongs to the Fur family.

1036672:TKWG RS19885
gene id: 1036672:TKWG_RS19885
uniprot id: I3UHI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1036672:TKWG RS09770
gene id: 1036672:TKWG_RS09770
uniprot id: I3UC52
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02430
gene id: 1036672:TKWG_RS02430
uniprot id: I3U868
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS00685
gene id: 1036672:TKWG_RS00685
uniprot id: I3U780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13845
gene id: 1036672:TKWG_RS13845
uniprot id: I3UE98
names: Similarity
messages: Belongs to the UPF0053 family.

1036672:TKWG RS13425
gene id: 1036672:TKWG_RS13425
uniprot id: I3UE20
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1036672:TKWG RS13485
gene id: 1036672:TKWG_RS13485
uniprot id: I3UE32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1036672:TKWG RS12865
gene id: 1036672:TKWG_RS12865
uniprot id: I3UDR3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1036672:TKWG RS06465
gene id: 1036672:TKWG_RS06465
uniprot id: I3UAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1036672:TKWG RS09615
gene id: 1036672:TKWG_RS09615
uniprot id: I3UC21
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS18625
gene id: 1036672:TKWG_RS18625
uniprot id: I3UGU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS10265
gene id: 1036672:TKWG_RS10265
uniprot id: I3UCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1036672:TKWG RS03650
gene id: 1036672:TKWG_RS03650
uniprot id: I3U8U4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS13745
gene id: 1036672:TKWG_RS13745
uniprot id: I3UE76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS15440
gene id: 1036672:TKWG_RS15440
uniprot id: I3UF45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1036672:TKWG RS12695
gene id: 1036672:TKWG_RS12695
uniprot id: I3UDN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1036672:TKWG RS18650
gene id: 1036672:TKWG_RS18650
uniprot id: I3UGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS19455
gene id: 1036672:TKWG_RS19455
uniprot id: I3UHA2
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS03765
gene id: 1036672:TKWG_RS03765
uniprot id: I3U8W6
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06935
gene id: 1036672:TKWG_RS06935
uniprot id: I3UAN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1036672:TKWG RS00345
gene id: 1036672:TKWG_RS00345
uniprot id: I3U715
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1036672:TKWG RS14095
gene id: 1036672:TKWG_RS14095
uniprot id: I3UEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS14225
gene id: 1036672:TKWG_RS14225
uniprot id: I3UEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS02560
gene id: 1036672:TKWG_RS02560
uniprot id: I3U891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1036672:TKWG RS13365
gene id: 1036672:TKWG_RS13365
uniprot id: I3UE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS14050
gene id: 1036672:TKWG_RS14050
uniprot id: I3UED7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1036672:TKWG RS15435
gene id: 1036672:TKWG_RS15435
uniprot id: I3UF44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1036672:TKWG RS19525
gene id: 1036672:TKWG_RS19525
uniprot id: I3UHB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1036672:TKWG RS03595
gene id: 1036672:TKWG_RS03595
uniprot id: I3U8T3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1036672:TKWG RS02950
gene id: 1036672:TKWG_RS02950
uniprot id: I3U8G6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1036672:TKWG RS10120
gene id: 1036672:TKWG_RS10120
uniprot id: I3UCB6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1036672:TKWG RS05360
gene id: 1036672:TKWG_RS05360
uniprot id: I3U9S7
names: Similarity
messages: Belongs to the Rht family.

1036672:TKWG RS11805
gene id: 1036672:TKWG_RS11805
uniprot id: I3UD78
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1036672:TKWG RS09725
gene id: 1036672:TKWG_RS09725
uniprot id: I3UC41
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1036672:TKWG RS05590
gene id: 1036672:TKWG_RS05590
uniprot id: I3U9X4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1036672:TKWG RS06040
gene id: 1036672:TKWG_RS06040
uniprot id: I3UA64
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS16405
gene id: 1036672:TKWG_RS16405
uniprot id: I3UFN6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1036672:TKWG RS13125
gene id: 1036672:TKWG_RS13125
uniprot id: I3UDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1036672:TKWG RS01590
gene id: 1036672:TKWG_RS01590
uniprot id: I3U7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS13825
gene id: 1036672:TKWG_RS13825
uniprot id: I3UE93
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1036672:TKWG RS17050
gene id: 1036672:TKWG_RS17050
uniprot id: I3UFZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1036672:TKWG RS02545
gene id: 1036672:TKWG_RS02545
uniprot id: I3U888
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS25140
gene id: 1036672:TKWG_RS25140
uniprot id: I3UEB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS15785
gene id: 1036672:TKWG_RS15785
uniprot id: I3UFB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS19545
gene id: 1036672:TKWG_RS19545
uniprot id: I3UHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1036672:TKWG RS14235
gene id: 1036672:TKWG_RS14235
uniprot id: I3UEI0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS06460
gene id: 1036672:TKWG_RS06460
uniprot id: I3UAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane

1036672:TKWG RS14720
gene id: 1036672:TKWG_RS14720
uniprot id: I3UES2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1036672:TKWG RS15500
gene id: 1036672:TKWG_RS15500
uniprot id: I3UF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1036672:TKWG RS09405
gene id: 1036672:TKWG_RS09405
uniprot id: I3UBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1036672:TKWG RS10040
gene id: 1036672:TKWG_RS10040
uniprot id: I3UCA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1036672:TKWG RS13280
gene id: 1036672:TKWG_RS13280
uniprot id: I3UDZ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS16365
gene id: 1036672:TKWG_RS16365
uniprot id: I3UFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1036672:TKWG RS01170
gene id: 1036672:TKWG_RS01170
uniprot id: I3U7H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS09940
gene id: 1036672:TKWG_RS09940
uniprot id: I3UC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

1036672:TKWG RS13420
gene id: 1036672:TKWG_RS13420
uniprot id: I3UE19
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1036672:TKWG RS08390
gene id: 1036672:TKWG_RS08390
uniprot id: I3UBF0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1036672:TKWG RS20880
gene id: 1036672:TKWG_RS20880
uniprot id: I3U775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS07490
gene id: 1036672:TKWG_RS07490
uniprot id: I3UAY6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS17360
gene id: 1036672:TKWG_RS17360
uniprot id: I3UG55
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1036672:TKWG RS04655
gene id: 1036672:TKWG_RS04655
uniprot id: I3U9D7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08335
gene id: 1036672:TKWG_RS08335
uniprot id: I3UBE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08260
gene id: 1036672:TKWG_RS08260
uniprot id: I3UBC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1036672:TKWG RS12645
gene id: 1036672:TKWG_RS12645
uniprot id: I3UDM7
names: Similarity
messages: Belongs to the threonine synthase family.

1036672:TKWG RS15850
gene id: 1036672:TKWG_RS15850
uniprot id: I3UFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS07575
gene id: 1036672:TKWG_RS07575
uniprot id: I3UB03
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS09170
gene id: 1036672:TKWG_RS09170
uniprot id: I3UBT5
names: Similarity
messages: Belongs to the pirin family.

1036672:TKWG RS01580
gene id: 1036672:TKWG_RS01580
uniprot id: I3U7Q7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1036672:TKWG RS13670
gene id: 1036672:TKWG_RS13670
uniprot id: I3UE64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS04350
gene id: 1036672:TKWG_RS04350
uniprot id: I3U978
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS05765
gene id: 1036672:TKWG_RS05765
uniprot id: I3UA11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1036672:TKWG RS10400
gene id: 1036672:TKWG_RS10400
uniprot id: I3UCG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1036672:TKWG RS10255
gene id: 1036672:TKWG_RS10255
uniprot id: I3UCD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1036672:TKWG RS11080
gene id: 1036672:TKWG_RS11080
uniprot id: I3UCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13135
gene id: 1036672:TKWG_RS13135
uniprot id: I3UDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1036672:TKWG RS09540
gene id: 1036672:TKWG_RS09540
uniprot id: I3UC06
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1036672:TKWG RS07675
gene id: 1036672:TKWG_RS07675
uniprot id: I3UB21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS05185
gene id: 1036672:TKWG_RS05185
uniprot id: I3U9P4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1036672:TKWG RS09155
gene id: 1036672:TKWG_RS09155
uniprot id: I3UBT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1036672:TKWG RS10340
gene id: 1036672:TKWG_RS10340
uniprot id: I3UCF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1036672:TKWG RS12575
gene id: 1036672:TKWG_RS12575
uniprot id: I3UDL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS02650
gene id: 1036672:TKWG_RS02650
uniprot id: I3U8A8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1036672:TKWG RS04675
gene id: 1036672:TKWG_RS04675
uniprot id: I3U9D9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1036672:TKWG RS08050
gene id: 1036672:TKWG_RS08050
uniprot id: I3UB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1036672:TKWG RS11335
gene id: 1036672:TKWG_RS11335
uniprot id: I3UCY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS17785
gene id: 1036672:TKWG_RS17785
uniprot id: I3UGD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS12585
gene id: 1036672:TKWG_RS12585
uniprot id: I3UDL6
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS11700
gene id: 1036672:TKWG_RS11700
uniprot id: I3UD53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1036672:TKWG RS06760
gene id: 1036672:TKWG_RS06760
uniprot id: I3UAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1036672:TKWG RS06165
gene id: 1036672:TKWG_RS06165
uniprot id: I3UA89
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS09315
gene id: 1036672:TKWG_RS09315
uniprot id: I3UBW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1036672:TKWG RS21010
gene id: 1036672:TKWG_RS21010
uniprot id: I3U899
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1036672:TKWG RS08905
gene id: 1036672:TKWG_RS08905
uniprot id: I3UBN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1036672:TKWG RS05255
gene id: 1036672:TKWG_RS05255
uniprot id: I3U9Q7
names: Similarity
messages: Belongs to the SCO1/2 family.

1036672:TKWG RS05875
gene id: 1036672:TKWG_RS05875
uniprot id: I3UA34
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1036672:TKWG RS01135
gene id: 1036672:TKWG_RS01135
uniprot id: I3U7G9
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1036672:TKWG RS17270
gene id: 1036672:TKWG_RS17270
uniprot id: I3UG38
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1036672:TKWG RS03940
gene id: 1036672:TKWG_RS03940
uniprot id: I3U901
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1036672:TKWG RS12040
gene id: 1036672:TKWG_RS12040
uniprot id: I3UDB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS03125
gene id: 1036672:TKWG_RS03125
uniprot id: I3U8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS18605
gene id: 1036672:TKWG_RS18605
uniprot id: I3UGT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS05300
gene id: 1036672:TKWG_RS05300
uniprot id: I3U9R5
names: Similarity
messages: Belongs to the asparaginase 1 family.

1036672:TKWG RS03780
gene id: 1036672:TKWG_RS03780
uniprot id: I3U8W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1036672:TKWG RS06720
gene id: 1036672:TKWG_RS06720
uniprot id: I3UAJ7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1036672:TKWG RS04215
gene id: 1036672:TKWG_RS04215
uniprot id: I3U953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS05455
gene id: 1036672:TKWG_RS05455
uniprot id: I3U9U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1036672:TKWG RS09510
gene id: 1036672:TKWG_RS09510
uniprot id: I3UC02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1036672:TKWG RS15590
gene id: 1036672:TKWG_RS15590
uniprot id: I3UF77
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS11930
gene id: 1036672:TKWG_RS11930
uniprot id: I3UDA0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS03235
gene id: 1036672:TKWG_RS03235
uniprot id: I3U8M1
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1036672:TKWG RS11650
gene id: 1036672:TKWG_RS11650
uniprot id: I3UD48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1036672:TKWG RS08805
gene id: 1036672:TKWG_RS08805
uniprot id: I3UBM5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1036672:TKWG RS09580
gene id: 1036672:TKWG_RS09580
uniprot id: I3UC14
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS09305
gene id: 1036672:TKWG_RS09305
uniprot id: I3UBV9
names: Similarity
messages: Belongs to the SCO1/2 family.

1036672:TKWG RS02755
gene id: 1036672:TKWG_RS02755
uniprot id: I3U8D0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1036672:TKWG RS01320
gene id: 1036672:TKWG_RS01320
uniprot id: I3U7K8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1036672:TKWG RS09125
gene id: 1036672:TKWG_RS09125
uniprot id: I3UBS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1036672:TKWG RS08875
gene id: 1036672:TKWG_RS08875
uniprot id: I3UBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

1036672:TKWG RS05785
gene id: 1036672:TKWG_RS05785
uniprot id: I3UA16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1036672:TKWG RS04030
gene id: 1036672:TKWG_RS04030
uniprot id: I3U916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10940
gene id: 1036672:TKWG_RS10940
uniprot id: I3UCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1036672:TKWG RS02365
gene id: 1036672:TKWG_RS02365
uniprot id: I3U857
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS10005
gene id: 1036672:TKWG_RS10005
uniprot id: I3UC94
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1036672:TKWG RS09870
gene id: 1036672:TKWG_RS09870
uniprot id: I3UC67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1036672:TKWG RS08010
gene id: 1036672:TKWG_RS08010
uniprot id: I3UB76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1036672:TKWG RS16195
gene id: 1036672:TKWG_RS16195
uniprot id: I3UFJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS19540
gene id: 1036672:TKWG_RS19540
uniprot id: I3UHB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1036672:TKWG RS19765
gene id: 1036672:TKWG_RS19765
uniprot id: I3UHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS04340
gene id: 1036672:TKWG_RS04340
uniprot id: I3U977
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1036672:TKWG RS19875
gene id: 1036672:TKWG_RS19875
uniprot id: I3UHI4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1036672:TKWG RS06000
gene id: 1036672:TKWG_RS06000
uniprot id: I3UA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS20765
gene id: 1036672:TKWG_RS20765
uniprot id: I3UI14
names: Similarity
messages: Belongs to the peptidase S24 family.

1036672:TKWG RS10275
gene id: 1036672:TKWG_RS10275
uniprot id: I3UCE2
names: Similarity
messages: Belongs to the P(II) protein family.

1036672:TKWG RS25260
gene id: 1036672:TKWG_RS25260
uniprot id: I3UFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS13635
gene id: 1036672:TKWG_RS13635
uniprot id: I3UE57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS10960
gene id: 1036672:TKWG_RS10960
uniprot id: I3UCS2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1036672:TKWG RS04685
gene id: 1036672:TKWG_RS04685
uniprot id: I3U9E0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1036672:TKWG RS19565
gene id: 1036672:TKWG_RS19565
uniprot id: I3UHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS08585
gene id: 1036672:TKWG_RS08585
uniprot id: I3UBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1036672:TKWG RS03740
gene id: 1036672:TKWG_RS03740
uniprot id: I3U8W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1036672:TKWG RS12055
gene id: 1036672:TKWG_RS12055
uniprot id: I3UDC1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1036672:TKWG RS10460
gene id: 1036672:TKWG_RS10460
uniprot id: I3UCH9
names: Subcellular Location Annotation
messages: Cytoplasm

1036672:TKWG RS04575
gene id: 1036672:TKWG_RS04575
uniprot id: I3U9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1036672:TKWG RS16730
gene id: 1036672:TKWG_RS16730
uniprot id: I3UFT8
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS20475
gene id: 1036672:TKWG_RS20475
uniprot id: I3UHW2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1036672:TKWG RS02245
gene id: 1036672:TKWG_RS02245
uniprot id: I3U836
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1036672:TKWG RS08220
gene id: 1036672:TKWG_RS08220
uniprot id: I3UBB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1036672:TKWG RS13085
gene id: 1036672:TKWG_RS13085
uniprot id: I3UDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS16690
gene id: 1036672:TKWG_RS16690
uniprot id: I3UFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1036672:TKWG RS06035
gene id: 1036672:TKWG_RS06035
uniprot id: I3UA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS00855
gene id: 1036672:TKWG_RS00855
uniprot id: I3U7B0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS07825
gene id: 1036672:TKWG_RS07825
uniprot id: I3UB47
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1036672:TKWG RS08295
gene id: 1036672:TKWG_RS08295
uniprot id: I3UBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1036672:TKWG RS01045
gene id: 1036672:TKWG_RS01045
uniprot id: I3U7E9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1036672:TKWG RS17160
gene id: 1036672:TKWG_RS17160
uniprot id: I3UG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS02480
gene id: 1036672:TKWG_RS02480
uniprot id: I3U875
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS16920
gene id: 1036672:TKWG_RS16920
uniprot id: I3UFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10390
gene id: 1036672:TKWG_RS10390
uniprot id: I3UCG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1036672:TKWG RS16515
gene id: 1036672:TKWG_RS16515
uniprot id: I3UFQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1036672:TKWG RS14150
gene id: 1036672:TKWG_RS14150
uniprot id: I3UEG1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1036672:TKWG RS08920
gene id: 1036672:TKWG_RS08920
uniprot id: I3UBP1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1036672:TKWG RS02110
gene id: 1036672:TKWG_RS02110
uniprot id: I3U812
names: Similarity
messages: Belongs to the pirin family.

1036672:TKWG RS05660
gene id: 1036672:TKWG_RS05660
uniprot id: I3U9Z0
names: Similarity
messages: Belongs to the UxaA family.

1036672:TKWG RS07890
gene id: 1036672:TKWG_RS07890
uniprot id: I3UB58
names: Similarity
messages: Belongs to the RutC family.

1036672:TKWG RS15765
gene id: 1036672:TKWG_RS15765
uniprot id: I3UFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS03950
gene id: 1036672:TKWG_RS03950
uniprot id: I3U903
names: Similarity
messages: Belongs to the TPP enzyme family.

1036672:TKWG RS25120
gene id: 1036672:TKWG_RS25120
uniprot id: I3UEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS14695
gene id: 1036672:TKWG_RS14695
uniprot id: I3UER8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1036672:TKWG RS10250
gene id: 1036672:TKWG_RS10250
uniprot id: I3UCD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1036672:TKWG RS18045
gene id: 1036672:TKWG_RS18045
uniprot id: I3UGI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1036672:TKWG RS16225
gene id: 1036672:TKWG_RS16225
uniprot id: I3UFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1036672:TKWG RS06080
gene id: 1036672:TKWG_RS06080
uniprot id: I3UA73
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1036672:TKWG RS13105
gene id: 1036672:TKWG_RS13105
uniprot id: I3UDW0
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1036672:TKWG RS13400
gene id: 1036672:TKWG_RS13400
uniprot id: I3UE15
names: Similarity
messages: Belongs to the citrate synthase family.

1036672:TKWG RS03355
gene id: 1036672:TKWG_RS03355
uniprot id: I3U8P4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1036672:TKWG RS13325
gene id: 1036672:TKWG_RS13325
uniprot id: I3UE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS04420
gene id: 1036672:TKWG_RS04420
uniprot id: I3U990
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS15465
gene id: 1036672:TKWG_RS15465
uniprot id: I3UF50
names: Similarity
messages: Belongs to the peptidase C56 family.

1036672:TKWG RS13090
gene id: 1036672:TKWG_RS13090
uniprot id: I3UDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS09955
gene id: 1036672:TKWG_RS09955
uniprot id: I3UC84
names: Similarity
messages: Belongs to the peptidase S66 family.

1036672:TKWG RS14890
gene id: 1036672:TKWG_RS14890
uniprot id: I3UEV4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1036672:TKWG RS13710
gene id: 1036672:TKWG_RS13710
uniprot id: I3UE70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS05855
gene id: 1036672:TKWG_RS05855
uniprot id: I3UA29
names: Similarity
messages: Belongs to the barstar family.

1036672:TKWG RS16150
gene id: 1036672:TKWG_RS16150
uniprot id: I3UFI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS19935
gene id: 1036672:TKWG_RS19935
uniprot id: I3UHJ8
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS03590
gene id: 1036672:TKWG_RS03590
uniprot id: I3U8T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1036672:TKWG RS05760
gene id: 1036672:TKWG_RS05760
uniprot id: I3UA10
names: Similarity
messages: Belongs to the PhoH family.

1036672:TKWG RS05930
gene id: 1036672:TKWG_RS05930
uniprot id: I3UA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1036672:TKWG RS10860
gene id: 1036672:TKWG_RS10860
uniprot id: I3UCQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1036672:TKWG RS14270
gene id: 1036672:TKWG_RS14270
uniprot id: I3UEI7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS10980
gene id: 1036672:TKWG_RS10980
uniprot id: I3UCS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1036672:TKWG RS12190
gene id: 1036672:TKWG_RS12190
uniprot id: I3UDE4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1036672:TKWG RS19395
gene id: 1036672:TKWG_RS19395
uniprot id: I3UH90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1036672:TKWG RS10420
gene id: 1036672:TKWG_RS10420
uniprot id: I3UCH3
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS10895
gene id: 1036672:TKWG_RS10895
uniprot id: I3UCQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1036672:TKWG RS12115
gene id: 1036672:TKWG_RS12115
uniprot id: I3UDD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1036672:TKWG RS00380
gene id: 1036672:TKWG_RS00380
uniprot id: I3U722
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1036672:TKWG RS17530
gene id: 1036672:TKWG_RS17530
uniprot id: I3UG89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS13965
gene id: 1036672:TKWG_RS13965
uniprot id: I3UEC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1036672:TKWG RS16130
gene id: 1036672:TKWG_RS16130
uniprot id: I3UFI1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1036672:TKWG RS05795
gene id: 1036672:TKWG_RS05795
uniprot id: I3UA18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1036672:TKWG RS18095
gene id: 1036672:TKWG_RS18095
uniprot id: I3UGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1036672:TKWG RS03510
gene id: 1036672:TKWG_RS03510
uniprot id: I3U8R7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS11915
gene id: 1036672:TKWG_RS11915
uniprot id: I3UD97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS21585
gene id: 1036672:TKWG_RS21585
uniprot id: I3UD68
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS15690
gene id: 1036672:TKWG_RS15690
uniprot id: I3UF95
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS21755
gene id: 1036672:TKWG_RS21755
uniprot id: I3UEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1036672:TKWG RS17380
gene id: 1036672:TKWG_RS17380
uniprot id: I3UG60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13010
gene id: 1036672:TKWG_RS13010
uniprot id: I3UDU4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1036672:TKWG RS03150
gene id: 1036672:TKWG_RS03150
uniprot id: I3U8K3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1036672:TKWG RS05520
gene id: 1036672:TKWG_RS05520
uniprot id: I3U9W0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS04995
gene id: 1036672:TKWG_RS04995
uniprot id: I3U9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1036672:TKWG RS11625
gene id: 1036672:TKWG_RS11625
uniprot id: I3UD45
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1036672:TKWG RS18725
gene id: 1036672:TKWG_RS18725
uniprot id: I3UGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS08455
gene id: 1036672:TKWG_RS08455
uniprot id: I3UBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS12975
gene id: 1036672:TKWG_RS12975
uniprot id: I3UDT7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1036672:TKWG RS19340
gene id: 1036672:TKWG_RS19340
uniprot id: I3UH80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1036672:TKWG RS08925
gene id: 1036672:TKWG_RS08925
uniprot id: I3UBP2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1036672:TKWG RS01195
gene id: 1036672:TKWG_RS01195
uniprot id: I3U7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS18410
gene id: 1036672:TKWG_RS18410
uniprot id: I3UGQ3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1036672:TKWG RS16285
gene id: 1036672:TKWG_RS16285
uniprot id: I3UFL4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1036672:TKWG RS18080
gene id: 1036672:TKWG_RS18080
uniprot id: I3UGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS01300
gene id: 1036672:TKWG_RS01300
uniprot id: I3U7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS19060
gene id: 1036672:TKWG_RS19060
uniprot id: I3UH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS04820
gene id: 1036672:TKWG_RS04820
uniprot id: I3U9H0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS11240
gene id: 1036672:TKWG_RS11240
uniprot id: I3UCW9
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS04265
gene id: 1036672:TKWG_RS04265
uniprot id: I3U963
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1036672:TKWG RS13410
gene id: 1036672:TKWG_RS13410
uniprot id: I3UE17
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1036672:TKWG RS04260
gene id: 1036672:TKWG_RS04260
uniprot id: I3U962
names: Similarity
messages: Belongs to the RuBisCO large chain family.

1036672:TKWG RS20660
gene id: 1036672:TKWG_RS20660
uniprot id: I3UHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1036672:TKWG RS13995
gene id: 1036672:TKWG_RS13995
uniprot id: I3UEC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS02185
gene id: 1036672:TKWG_RS02185
uniprot id: I3U827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS18400
gene id: 1036672:TKWG_RS18400
uniprot id: I3UGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS06325
gene id: 1036672:TKWG_RS06325
uniprot id: I3UAC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS19940
gene id: 1036672:TKWG_RS19940
uniprot id: I3UHJ9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1036672:TKWG RS16930
gene id: 1036672:TKWG_RS16930
uniprot id: I3UFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS04450
gene id: 1036672:TKWG_RS04450
uniprot id: I3U999
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS17970
gene id: 1036672:TKWG_RS17970
uniprot id: I3UGG7
names: Similarity
messages: Belongs to the pirin family.

1036672:TKWG RS01385
gene id: 1036672:TKWG_RS01385
uniprot id: I3U7M2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1036672:TKWG RS12095
gene id: 1036672:TKWG_RS12095
uniprot id: I3UDC6
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS02770
gene id: 1036672:TKWG_RS02770
uniprot id: I3U8D3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1036672:TKWG RS11895
gene id: 1036672:TKWG_RS11895
uniprot id: I3UD94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS17925
gene id: 1036672:TKWG_RS17925
uniprot id: I3UGF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS16070
gene id: 1036672:TKWG_RS16070
uniprot id: I3UFH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS19475
gene id: 1036672:TKWG_RS19475
uniprot id: I3UHA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1036672:TKWG RS05465
gene id: 1036672:TKWG_RS05465
uniprot id: I3U9V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1036672:TKWG RS06765
gene id: 1036672:TKWG_RS06765
uniprot id: I3UAK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS09935
gene id: 1036672:TKWG_RS09935
uniprot id: I3UC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS16310
gene id: 1036672:TKWG_RS16310
uniprot id: I3UFL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS02355
gene id: 1036672:TKWG_RS02355
uniprot id: I3U855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS03580
gene id: 1036672:TKWG_RS03580
uniprot id: I3U8S9
names: Similarity
messages: Belongs to the UPF0250 family.

1036672:TKWG RS07820
gene id: 1036672:TKWG_RS07820
uniprot id: I3UB46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1036672:TKWG RS16165
gene id: 1036672:TKWG_RS16165
uniprot id: I3UFI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS14265
gene id: 1036672:TKWG_RS14265
uniprot id: I3UEI6
names: Similarity
messages: Belongs to the UPF0246 family.

1036672:TKWG RS14910
gene id: 1036672:TKWG_RS14910
uniprot id: I3UEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1036672:TKWG RS04320
gene id: 1036672:TKWG_RS04320
uniprot id: I3U973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS15855
gene id: 1036672:TKWG_RS15855
uniprot id: I3UFC6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1036672:TKWG RS14860
gene id: 1036672:TKWG_RS14860
uniprot id: I3UEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS13650
gene id: 1036672:TKWG_RS13650
uniprot id: I3UE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS20105
gene id: 1036672:TKWG_RS20105
uniprot id: I3UHN6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1036672:TKWG RS09365
gene id: 1036672:TKWG_RS09365
uniprot id: I3UBX2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS14410
gene id: 1036672:TKWG_RS14410
uniprot id: I3UEL7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1036672:TKWG RS11765
gene id: 1036672:TKWG_RS11765
uniprot id: I3UD69
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1036672:TKWG RS05180
gene id: 1036672:TKWG_RS05180
uniprot id: I3U9P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1036672:TKWG RS09605
gene id: 1036672:TKWG_RS09605
uniprot id: I3UC19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS19510
gene id: 1036672:TKWG_RS19510
uniprot id: I3UHB4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1036672:TKWG RS06480
gene id: 1036672:TKWG_RS06480
uniprot id: I3UAF5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1036672:TKWG RS14200
gene id: 1036672:TKWG_RS14200
uniprot id: I3UEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS15965
gene id: 1036672:TKWG_RS15965
uniprot id: I3UFF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS09965
gene id: 1036672:TKWG_RS09965
uniprot id: I3UC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1036672:TKWG RS02915
gene id: 1036672:TKWG_RS02915
uniprot id: I3U8F9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1036672:TKWG RS20665
gene id: 1036672:TKWG_RS20665
uniprot id: I3UHZ4
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1036672:TKWG RS10885
gene id: 1036672:TKWG_RS10885
uniprot id: I3UCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1036672:TKWG RS16640
gene id: 1036672:TKWG_RS16640
uniprot id: I3UFS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1036672:TKWG RS06420
gene id: 1036672:TKWG_RS06420
uniprot id: I3UAE4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1036672:TKWG RS11830
gene id: 1036672:TKWG_RS11830
uniprot id: I3UD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1036672:TKWG RS13855
gene id: 1036672:TKWG_RS13855
uniprot id: I3UEA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS01145
gene id: 1036672:TKWG_RS01145
uniprot id: I3U7H1
names: Similarity
messages: Belongs to the class-I fumarase family.

1036672:TKWG RS22920
gene id: 1036672:TKWG_RS22920
uniprot id: I3U8Y3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1036672:TKWG RS12420
gene id: 1036672:TKWG_RS12420
uniprot id: I3UDJ1
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS11800
gene id: 1036672:TKWG_RS11800
uniprot id: I3UD77
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1036672:TKWG RS13190
gene id: 1036672:TKWG_RS13190
uniprot id: I3UDX5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1036672:TKWG RS17890
gene id: 1036672:TKWG_RS17890
uniprot id: I3UGF1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS19290
gene id: 1036672:TKWG_RS19290
uniprot id: I3UH72
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS05480
gene id: 1036672:TKWG_RS05480
uniprot id: I3U9V2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1036672:TKWG RS10510
gene id: 1036672:TKWG_RS10510
uniprot id: I3UCI9
names: Similarity
messages: Belongs to the UxaA family.

1036672:TKWG RS17980
gene id: 1036672:TKWG_RS17980
uniprot id: I3UGG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1036672:TKWG RS03020
gene id: 1036672:TKWG_RS03020
uniprot id: I3U8H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1036672:TKWG RS08140
gene id: 1036672:TKWG_RS08140
uniprot id: I3UBA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS08045
gene id: 1036672:TKWG_RS08045
uniprot id: I3UB84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1036672:TKWG RS16175
gene id: 1036672:TKWG_RS16175
uniprot id: I3UFJ0
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1036672:TKWG RS13040
gene id: 1036672:TKWG_RS13040
uniprot id: I3UDV0
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1036672:TKWG RS00810
gene id: 1036672:TKWG_RS00810
uniprot id: I3U7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS06795
gene id: 1036672:TKWG_RS06795
uniprot id: I3UAL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS19055
gene id: 1036672:TKWG_RS19055
uniprot id: I3UH23
names: Similarity
messages: Belongs to the oxoprolinase family.

1036672:TKWG RS06665
gene id: 1036672:TKWG_RS06665
uniprot id: I3UAJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1036672:TKWG RS13655
gene id: 1036672:TKWG_RS13655
uniprot id: I3UE61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08365
gene id: 1036672:TKWG_RS08365
uniprot id: I3UBE6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1036672:TKWG RS00220
gene id: 1036672:TKWG_RS00220
uniprot id: I3U6Y7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS14435
gene id: 1036672:TKWG_RS14435
uniprot id: I3UEM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS19040
gene id: 1036672:TKWG_RS19040
uniprot id: I3UH21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS15925
gene id: 1036672:TKWG_RS15925
uniprot id: I3UFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS07815
gene id: 1036672:TKWG_RS07815
uniprot id: I3UB45
names: Similarity
messages: Belongs to the BolA/IbaG family.

1036672:TKWG RS16040
gene id: 1036672:TKWG_RS16040
uniprot id: I3UFG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS09900
gene id: 1036672:TKWG_RS09900
uniprot id: I3UC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1036672:TKWG RS18635
gene id: 1036672:TKWG_RS18635
uniprot id: I3UGU2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1036672:TKWG RS18090
gene id: 1036672:TKWG_RS18090
uniprot id: I3UGI9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS01910
gene id: 1036672:TKWG_RS01910
uniprot id: I3U7X4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1036672:TKWG RS09235
gene id: 1036672:TKWG_RS09235
uniprot id: I3UBU8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1036672:TKWG RS14595
gene id: 1036672:TKWG_RS14595
uniprot id: I3UEQ0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS14835
gene id: 1036672:TKWG_RS14835
uniprot id: I3UEU3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1036672:TKWG RS20465
gene id: 1036672:TKWG_RS20465
uniprot id: I3UHW0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS12780
gene id: 1036672:TKWG_RS12780
uniprot id: I3UDP9
names: Similarity
messages: Belongs to the LOG family.

1036672:TKWG RS08840
gene id: 1036672:TKWG_RS08840
uniprot id: I3UBN0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1036672:TKWG RS03080
gene id: 1036672:TKWG_RS03080
uniprot id: I3U8I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1036672:TKWG RS02945
gene id: 1036672:TKWG_RS02945
uniprot id: I3U8G5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1036672:TKWG RS00910
gene id: 1036672:TKWG_RS00910
uniprot id: I3U7C3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1036672:TKWG RS03095
gene id: 1036672:TKWG_RS03095
uniprot id: I3U8J0
names: Similarity
messages: Belongs to the peptidase C40 family.

1036672:TKWG RS09440
gene id: 1036672:TKWG_RS09440
uniprot id: I3UBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1036672:TKWG RS04410
gene id: 1036672:TKWG_RS04410
uniprot id: I3U988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS06095
gene id: 1036672:TKWG_RS06095
uniprot id: I3UA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1036672:TKWG RS06190
gene id: 1036672:TKWG_RS06190
uniprot id: I3UA95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1036672:TKWG RS02910
gene id: 1036672:TKWG_RS02910
uniprot id: I3U8F8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1036672:TKWG RS11275
gene id: 1036672:TKWG_RS11275
uniprot id: I3UCX5
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS10955
gene id: 1036672:TKWG_RS10955
uniprot id: I3UCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10620
gene id: 1036672:TKWG_RS10620
uniprot id: I3UCK9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS02820
gene id: 1036672:TKWG_RS02820
uniprot id: I3U8E2
names: Similarity
messages: Belongs to the TrpC family.

1036672:TKWG RS08725
gene id: 1036672:TKWG_RS08725
uniprot id: I3UBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1036672:TKWG RS02725
gene id: 1036672:TKWG_RS02725
uniprot id: I3U8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS16170
gene id: 1036672:TKWG_RS16170
uniprot id: I3UFI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS05090
gene id: 1036672:TKWG_RS05090
uniprot id: I3U9M9
names: Similarity
messages: Belongs to the YggT family.

1036672:TKWG RS09190
gene id: 1036672:TKWG_RS09190
uniprot id: I3UBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1036672:TKWG RS09520
gene id: 1036672:TKWG_RS09520
uniprot id: I3UC04
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1036672:TKWG RS10445
gene id: 1036672:TKWG_RS10445
uniprot id: I3UCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1036672:TKWG RS12235
gene id: 1036672:TKWG_RS12235
uniprot id: I3UDF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1036672:TKWG RS08785
gene id: 1036672:TKWG_RS08785
uniprot id: I3UBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1036672:TKWG RS19860
gene id: 1036672:TKWG_RS19860
uniprot id: I3UHI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1036672:TKWG RS00335
gene id: 1036672:TKWG_RS00335
uniprot id: I3U713
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS19495
gene id: 1036672:TKWG_RS19495
uniprot id: I3UHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1036672:TKWG RS06255
gene id: 1036672:TKWG_RS06255
uniprot id: I3UAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS17115
gene id: 1036672:TKWG_RS17115
uniprot id: I3UG12
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1036672:TKWG RS01280
gene id: 1036672:TKWG_RS01280
uniprot id: I3U7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS01800
gene id: 1036672:TKWG_RS01800
uniprot id: I3U7U9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS02445
gene id: 1036672:TKWG_RS02445
uniprot id: I3U870
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1036672:TKWG RS10260
gene id: 1036672:TKWG_RS10260
uniprot id: I3UCD9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1036672:TKWG RS20300
gene id: 1036672:TKWG_RS20300
uniprot id: I3UHT2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1036672:TKWG RS09585
gene id: 1036672:TKWG_RS09585
uniprot id: I3UC15
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1036672:TKWG RS16295
gene id: 1036672:TKWG_RS16295
uniprot id: I3UFL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1036672:TKWG RS16420
gene id: 1036672:TKWG_RS16420
uniprot id: I3UFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1036672:TKWG RS19075
gene id: 1036672:TKWG_RS19075
uniprot id: I3UH26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS07285
gene id: 1036672:TKWG_RS07285
uniprot id: I3UAV2
names: Subcellular Location Annotation
messages: Periplasm

1036672:TKWG RS11340
gene id: 1036672:TKWG_RS11340
uniprot id: I3UCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS19035
gene id: 1036672:TKWG_RS19035
uniprot id: I3UH20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS20515
gene id: 1036672:TKWG_RS20515
uniprot id: I3UHW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS03175
gene id: 1036672:TKWG_RS03175
uniprot id: I3U8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS16505
gene id: 1036672:TKWG_RS16505
uniprot id: I3UFQ0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1036672:TKWG RS00860
gene id: 1036672:TKWG_RS00860
uniprot id: I3U7B1
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS09395
gene id: 1036672:TKWG_RS09395
uniprot id: I3UBY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1036672:TKWG RS08820
gene id: 1036672:TKWG_RS08820
uniprot id: I3UBM8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1036672:TKWG RS18115
gene id: 1036672:TKWG_RS18115
uniprot id: I3UGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1036672:TKWG RS07985
gene id: 1036672:TKWG_RS07985
uniprot id: I3UB73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1036672:TKWG RS21340
gene id: 1036672:TKWG_RS21340
uniprot id: I3UAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS11250
gene id: 1036672:TKWG_RS11250
uniprot id: I3UCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1036672:TKWG RS10500
gene id: 1036672:TKWG_RS10500
uniprot id: I3UCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS14310
gene id: 1036672:TKWG_RS14310
uniprot id: I3UEJ3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1036672:TKWG RS16145
gene id: 1036672:TKWG_RS16145
uniprot id: I3UFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS20035
gene id: 1036672:TKWG_RS20035
uniprot id: I3UHM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1036672:TKWG RS17420
gene id: 1036672:TKWG_RS17420
uniprot id: I3UG65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS25675
gene id: 1036672:TKWG_RS25675
uniprot id: I3U7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10245
gene id: 1036672:TKWG_RS10245
uniprot id: I3UCD6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1036672:TKWG RS14865
gene id: 1036672:TKWG_RS14865
uniprot id: I3UEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1036672:TKWG RS09555
gene id: 1036672:TKWG_RS09555
uniprot id: I3UC09
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1036672:TKWG RS00835
gene id: 1036672:TKWG_RS00835
uniprot id: I3U7A6
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1036672:TKWG RS15405
gene id: 1036672:TKWG_RS15405
uniprot id: I3UF38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS03960
gene id: 1036672:TKWG_RS03960
uniprot id: I3U904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS03945
gene id: 1036672:TKWG_RS03945
uniprot id: I3U902
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1036672:TKWG RS04775
gene id: 1036672:TKWG_RS04775
uniprot id: I3U9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1036672:TKWG RS11680
gene id: 1036672:TKWG_RS11680
uniprot id: I3UD51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1036672:TKWG RS01700
gene id: 1036672:TKWG_RS01700
uniprot id: I3U7T3
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1036672:TKWG RS08085
gene id: 1036672:TKWG_RS08085
uniprot id: I3UB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1036672:TKWG RS08955
gene id: 1036672:TKWG_RS08955
uniprot id: I3UBP8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1036672:TKWG RS14855
gene id: 1036672:TKWG_RS14855
uniprot id: I3UEU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1036672:TKWG RS04835
gene id: 1036672:TKWG_RS04835
uniprot id: I3U9H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS09595
gene id: 1036672:TKWG_RS09595
uniprot id: I3UC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS20500
gene id: 1036672:TKWG_RS20500
uniprot id: I3UHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS06905
gene id: 1036672:TKWG_RS06905
uniprot id: I3UAM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS10415
gene id: 1036672:TKWG_RS10415
uniprot id: I3UCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1036672:TKWG RS02090
gene id: 1036672:TKWG_RS02090
uniprot id: I3U808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS10365
gene id: 1036672:TKWG_RS10365
uniprot id: I3UCF9
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06060
gene id: 1036672:TKWG_RS06060
uniprot id: I3UA68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1036672:TKWG RS04930
gene id: 1036672:TKWG_RS04930
uniprot id: I3U9J6
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS21580
gene id: 1036672:TKWG_RS21580
uniprot id: I3UD67
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS06940
gene id: 1036672:TKWG_RS06940
uniprot id: I3UAN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1036672:TKWG RS15770
gene id: 1036672:TKWG_RS15770
uniprot id: I3UFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1036672:TKWG RS08960
gene id: 1036672:TKWG_RS08960
uniprot id: I3UBP9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1036672:TKWG RS09230
gene id: 1036672:TKWG_RS09230
uniprot id: I3UBU7
names: Similarity
messages: Belongs to the RutC family.

1036672:TKWG RS13260
gene id: 1036672:TKWG_RS13260
uniprot id: I3UDY8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1036672:TKWG RS10150
gene id: 1036672:TKWG_RS10150
uniprot id: I3UCB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS14345
gene id: 1036672:TKWG_RS14345
uniprot id: I3UEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10235
gene id: 1036672:TKWG_RS10235
uniprot id: I3UCD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1036672:TKWG RS02230
gene id: 1036672:TKWG_RS02230
uniprot id: I3U833
names: Similarity
messages: Belongs to the class-I fumarase family.

1036672:TKWG RS08135
gene id: 1036672:TKWG_RS08135
uniprot id: I3UBA0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1036672:TKWG RS12310
gene id: 1036672:TKWG_RS12310
uniprot id: I3UDG8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1036672:TKWG RS04295
gene id: 1036672:TKWG_RS04295
uniprot id: I3U970
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1036672:TKWG RS12245
gene id: 1036672:TKWG_RS12245
uniprot id: I3UDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1036672:TKWG RS12380
gene id: 1036672:TKWG_RS12380
uniprot id: I3UDI1
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1036672:TKWG RS15135
gene id: 1036672:TKWG_RS15135
uniprot id: I3UEZ4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS11430
gene id: 1036672:TKWG_RS11430
uniprot id: I3UD04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS15495
gene id: 1036672:TKWG_RS15495
uniprot id: I3UF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1036672:TKWG RS07905
gene id: 1036672:TKWG_RS07905
uniprot id: I3UB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1036672:TKWG RS16685
gene id: 1036672:TKWG_RS16685
uniprot id: I3UFT0
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS09875
gene id: 1036672:TKWG_RS09875
uniprot id: I3UC68
names: Similarity
messages: Belongs to the P(II) protein family.

1036672:TKWG RS00750
gene id: 1036672:TKWG_RS00750
uniprot id: I3U790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1036672:TKWG RS08285
gene id: 1036672:TKWG_RS08285
uniprot id: I3UBD0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1036672:TKWG RS15420
gene id: 1036672:TKWG_RS15420
uniprot id: I3UF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1036672:TKWG RS10290
gene id: 1036672:TKWG_RS10290
uniprot id: I3UCE5
names: Subcellular Location Annotation
messages: Cytoplasm

1036672:TKWG RS19980
gene id: 1036672:TKWG_RS19980
uniprot id: I3UHK8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1036672:TKWG RS04985
gene id: 1036672:TKWG_RS04985
uniprot id: I3U9K6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1036672:TKWG RS06260
gene id: 1036672:TKWG_RS06260
uniprot id: I3UAB1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1036672:TKWG RS03755
gene id: 1036672:TKWG_RS03755
uniprot id: I3U8W4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1036672:TKWG RS11135
gene id: 1036672:TKWG_RS11135
uniprot id: I3UCV4
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

1036672:TKWG RS18950
gene id: 1036672:TKWG_RS18950
uniprot id: I3UH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS01105
gene id: 1036672:TKWG_RS01105
uniprot id: I3U7G3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1036672:TKWG RS14920
gene id: 1036672:TKWG_RS14920
uniprot id: I3UEW1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1036672:TKWG RS15720
gene id: 1036672:TKWG_RS15720
uniprot id: I3UF98
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1036672:TKWG RS17955
gene id: 1036672:TKWG_RS17955
uniprot id: I3UGG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1036672:TKWG RS02265
gene id: 1036672:TKWG_RS02265
uniprot id: I3U840
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1036672:TKWG RS08210
gene id: 1036672:TKWG_RS08210
uniprot id: I3UBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1036672:TKWG RS14570
gene id: 1036672:TKWG_RS14570
uniprot id: I3UEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS12250
gene id: 1036672:TKWG_RS12250
uniprot id: I3UDF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1036672:TKWG RS14080
gene id: 1036672:TKWG_RS14080
uniprot id: I3UEE3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1036672:TKWG RS12880
gene id: 1036672:TKWG_RS12880
uniprot id: I3UDR8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS05850
gene id: 1036672:TKWG_RS05850
uniprot id: I3UA28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS02150
gene id: 1036672:TKWG_RS02150
uniprot id: I3U819
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS19470
gene id: 1036672:TKWG_RS19470
uniprot id: I3UHA5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1036672:TKWG RS04710
gene id: 1036672:TKWG_RS04710
uniprot id: I3U9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1036672:TKWG RS03670
gene id: 1036672:TKWG_RS03670
uniprot id: I3U8U7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1036672:TKWG RS17065
gene id: 1036672:TKWG_RS17065
uniprot id: I3UG02
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1036672:TKWG RS00250
gene id: 1036672:TKWG_RS00250
uniprot id: I3U6Z3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS19320
gene id: 1036672:TKWG_RS19320
uniprot id: I3UH75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1036672:TKWG RS07860
gene id: 1036672:TKWG_RS07860
uniprot id: I3UB53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1036672:TKWG RS17150
gene id: 1036672:TKWG_RS17150
uniprot id: I3UG19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS20020
gene id: 1036672:TKWG_RS20020
uniprot id: I3UHL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1036672:TKWG RS24430
gene id: 1036672:TKWG_RS24430
uniprot id: I3U8F7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1036672:TKWG RS20795
gene id: 1036672:TKWG_RS20795
uniprot id: I3UI20
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1036672:TKWG RS11790
gene id: 1036672:TKWG_RS11790
uniprot id: I3UD75
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1036672:TKWG RS15125
gene id: 1036672:TKWG_RS15125
uniprot id: I3UEZ3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS13120
gene id: 1036672:TKWG_RS13120
uniprot id: I3UDW3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1036672:TKWG RS09350
gene id: 1036672:TKWG_RS09350
uniprot id: I3UBW9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1036672:TKWG RS01775
gene id: 1036672:TKWG_RS01775
uniprot id: I3U7U4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS15870
gene id: 1036672:TKWG_RS15870
uniprot id: I3UFC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS08655
gene id: 1036672:TKWG_RS08655
uniprot id: I3UBJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1036672:TKWG RS07645
gene id: 1036672:TKWG_RS07645
uniprot id: I3UB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS10995
gene id: 1036672:TKWG_RS10995
uniprot id: I3UCS9
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1036672:TKWG RS04935
gene id: 1036672:TKWG_RS04935
uniprot id: I3U9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1036672:TKWG RS02890
gene id: 1036672:TKWG_RS02890
uniprot id: I3U8F4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1036672:TKWG RS18945
gene id: 1036672:TKWG_RS18945
uniprot id: I3UH03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1036672:TKWG RS07335
gene id: 1036672:TKWG_RS07335
uniprot id: I3UAW0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1036672:TKWG RS09255
gene id: 1036672:TKWG_RS09255
uniprot id: I3UBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1036672:TKWG RS14825
gene id: 1036672:TKWG_RS14825
uniprot id: I3UEU1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1036672:TKWG RS11795
gene id: 1036672:TKWG_RS11795
uniprot id: I3UD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS09310
gene id: 1036672:TKWG_RS09310
uniprot id: I3UBW0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1036672:TKWG RS08555
gene id: 1036672:TKWG_RS08555
uniprot id: I3UBI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1036672:TKWG RS13645
gene id: 1036672:TKWG_RS13645
uniprot id: I3UE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS07990
gene id: 1036672:TKWG_RS07990
uniprot id: I3UB74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1036672:TKWG RS19480
gene id: 1036672:TKWG_RS19480
uniprot id: I3UHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1036672:TKWG RS04815
gene id: 1036672:TKWG_RS04815
uniprot id: I3U9G9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1036672:TKWG RS20770
gene id: 1036672:TKWG_RS20770
uniprot id: I3UI15
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1036672:TKWG RS20610
gene id: 1036672:TKWG_RS20610
uniprot id: I3UHY3
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1036672:TKWG RS14640
gene id: 1036672:TKWG_RS14640
uniprot id: I3UEQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS09750
gene id: 1036672:TKWG_RS09750
uniprot id: I3UC46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS13495
gene id: 1036672:TKWG_RS13495
uniprot id: I3UE34
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1036672:TKWG RS13540
gene id: 1036672:TKWG_RS13540
uniprot id: I3UE41
names: Similarity
messages: Belongs to the HIBADH-related family.

1036672:TKWG RS14605
gene id: 1036672:TKWG_RS14605
uniprot id: I3UEQ2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1036672:TKWG RS02970
gene id: 1036672:TKWG_RS02970
uniprot id: I3U8G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1036672:TKWG RS12685
gene id: 1036672:TKWG_RS12685
uniprot id: I3UDN5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1036672:TKWG RS08265
gene id: 1036672:TKWG_RS08265
uniprot id: I3UBC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

1036672:TKWG RS03835
gene id: 1036672:TKWG_RS03835
uniprot id: I3U8X7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1036672:TKWG RS06840
gene id: 1036672:TKWG_RS06840
uniprot id: I3UAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1036672:TKWG RS02980
gene id: 1036672:TKWG_RS02980
uniprot id: I3U8H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1036672:TKWG RS19330
gene id: 1036672:TKWG_RS19330
uniprot id: I3UH78
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1036672:TKWG RS06870
gene id: 1036672:TKWG_RS06870
uniprot id: I3UAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1036672:TKWG RS15275
gene id: 1036672:TKWG_RS15275
uniprot id: I3UF17
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS07655
gene id: 1036672:TKWG_RS07655
uniprot id: I3UB18
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1036672:TKWG RS22875
gene id: 1036672:TKWG_RS22875
uniprot id: I3UHX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1036672:TKWG RS09805
gene id: 1036672:TKWG_RS09805
uniprot id: I3UC57
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1036672:TKWG RS06120
gene id: 1036672:TKWG_RS06120
uniprot id: I3UA81
names: Similarity
messages: Belongs to the YkuD family.

1036672:TKWG RS04925
gene id: 1036672:TKWG_RS04925
uniprot id: I3U9J5
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS11360
gene id: 1036672:TKWG_RS11360
uniprot id: I3UCZ1
names: Similarity
messages: Belongs to the GST superfamily.

1036672:TKWG RS11195
gene id: 1036672:TKWG_RS11195
uniprot id: I3UCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS10880
gene id: 1036672:TKWG_RS10880
uniprot id: I3UCQ6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1036672:TKWG RS07630
gene id: 1036672:TKWG_RS07630
uniprot id: I3UB13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1036672:TKWG RS09975
gene id: 1036672:TKWG_RS09975
uniprot id: I3UC89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1036672:TKWG RS15090
gene id: 1036672:TKWG_RS15090
uniprot id: I3UEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1036672:TKWG RS05095
gene id: 1036672:TKWG_RS05095
uniprot id: I3U9N0
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

1036672:TKWG RS14990
gene id: 1036672:TKWG_RS14990
uniprot id: I3UEX4
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS08780
gene id: 1036672:TKWG_RS08780
uniprot id: I3UBM2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1036672:TKWG RS16275
gene id: 1036672:TKWG_RS16275
uniprot id: I3UFL2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1036672:TKWG RS02550
gene id: 1036672:TKWG_RS02550
uniprot id: I3U889
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1036672:TKWG RS20340
gene id: 1036672:TKWG_RS20340
uniprot id: I3UHT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS09460
gene id: 1036672:TKWG_RS09460
uniprot id: I3UBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1036672:TKWG RS04040
gene id: 1036672:TKWG_RS04040
uniprot id: I3U917
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS04010
gene id: 1036672:TKWG_RS04010
uniprot id: I3U911
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1036672:TKWG RS03255
gene id: 1036672:TKWG_RS03255
uniprot id: I3U8M4
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

1036672:TKWG RS15520
gene id: 1036672:TKWG_RS15520
uniprot id: I3UF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1036672:TKWG RS17860
gene id: 1036672:TKWG_RS17860
uniprot id: I3UGE6
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1036672:TKWG RS14195
gene id: 1036672:TKWG_RS14195
uniprot id: I3UEH0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1036672:TKWG RS08430
gene id: 1036672:TKWG_RS08430
uniprot id: I3UBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

1036672:TKWG RS07835
gene id: 1036672:TKWG_RS07835
uniprot id: I3UB50
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS13035
gene id: 1036672:TKWG_RS13035
uniprot id: I3UDU9
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1036672:TKWG RS19070
gene id: 1036672:TKWG_RS19070
uniprot id: I3UH25
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS08005
gene id: 1036672:TKWG_RS08005
uniprot id: I3UB75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1036672:TKWG RS18420
gene id: 1036672:TKWG_RS18420
uniprot id: I3UGQ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1036672:TKWG RS20670
gene id: 1036672:TKWG_RS20670
uniprot id: I3UHZ5
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS19895
gene id: 1036672:TKWG_RS19895
uniprot id: I3UHI8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1036672:TKWG RS01310
gene id: 1036672:TKWG_RS01310
uniprot id: I3U7K6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS18880
gene id: 1036672:TKWG_RS18880
uniprot id: I3UGY9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1036672:TKWG RS14140
gene id: 1036672:TKWG_RS14140
uniprot id: I3UEF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1036672:TKWG RS02775
gene id: 1036672:TKWG_RS02775
uniprot id: I3U8D4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS06875
gene id: 1036672:TKWG_RS06875
uniprot id: I3UAM4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1036672:TKWG RS02635
gene id: 1036672:TKWG_RS02635
uniprot id: I3U8A6
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1036672:TKWG RS18320
gene id: 1036672:TKWG_RS18320
uniprot id: I3UGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1036672:TKWG RS01405
gene id: 1036672:TKWG_RS01405
uniprot id: I3U7M5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1036672:TKWG RS19465
gene id: 1036672:TKWG_RS19465
uniprot id: I3UHA4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1036672:TKWG RS06570
gene id: 1036672:TKWG_RS06570
uniprot id: I3UAH3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1036672:TKWG RS19375
gene id: 1036672:TKWG_RS19375
uniprot id: I3UH86
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1036672:TKWG RS15025
gene id: 1036672:TKWG_RS15025
uniprot id: I3UEY0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1036672:TKWG RS06170
gene id: 1036672:TKWG_RS06170
uniprot id: I3UA90
names: Subcellular Location Annotation
messages: Membrane

1036672:TKWG RS16605
gene id: 1036672:TKWG_RS16605
uniprot id: I3UFR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1036672:TKWG RS14060
gene id: 1036672:TKWG_RS14060
uniprot id: I3UED9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1036672:TKWG RS14635
gene id: 1036672:TKWG_RS14635
uniprot id: I3UEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1036672:TKWG RS15160
gene id: 1036672:TKWG_RS15160
uniprot id: I3UEZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1036672:TKWG RS08150
gene id: 1036672:TKWG_RS08150
uniprot id: I3UBA3
names: Similarity
messages: Belongs to the UPF0751 family.

1036672:TKWG RS03070
gene id: 1036672:TKWG_RS03070
uniprot id: I3U8I5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.