102684:I6H76 RS04400
gene id: 102684:I6H76_RS04400
uniprot id: A0A380KKR3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09795
gene id: 102684:I6H76_RS09795
uniprot id: A0A380KMK6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

102684:I6H76 RS06800
gene id: 102684:I6H76_RS06800
uniprot id: A0A380KPW9
names: Similarity
messages: Belongs to the UPF0236 family.

102684:I6H76 RS08410
gene id: 102684:I6H76_RS08410
uniprot id: A0A380KND2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

102684:I6H76 RS01310
gene id: 102684:I6H76_RS01310
uniprot id: A0A380KPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS07615
gene id: 102684:I6H76_RS07615
uniprot id: A0A380KP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

102684:I6H76 RS08060
gene id: 102684:I6H76_RS08060
uniprot id: A0A380KNY9
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

102684:I6H76 RS09215
gene id: 102684:I6H76_RS09215
uniprot id: A0A380KNH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

102684:I6H76 RS00340
gene id: 102684:I6H76_RS00340
uniprot id: A0A380KMA9
names: Subcellular Location Annotation
messages: Cytoplasm

102684:I6H76 RS05415
gene id: 102684:I6H76_RS05415
uniprot id: A0A0U2M0Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

102684:I6H76 RS00530
gene id: 102684:I6H76_RS00530
uniprot id: A0A380KMU7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

102684:I6H76 RS08825
gene id: 102684:I6H76_RS08825
uniprot id: A0A380KQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

102684:I6H76 RS05815
gene id: 102684:I6H76_RS05815
uniprot id: A0A380KQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

102684:I6H76 RS03915
gene id: 102684:I6H76_RS03915
uniprot id: A0A380KKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

102684:I6H76 RS05150
gene id: 102684:I6H76_RS05150
uniprot id: A0A380KMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04670
gene id: 102684:I6H76_RS04670
uniprot id: A0A0U3EVX5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

102684:I6H76 RS04525
gene id: 102684:I6H76_RS04525
uniprot id: A0A380KK67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03580
gene id: 102684:I6H76_RS03580
uniprot id: A0A380KM71
names: Similarity
messages: Belongs to the UPF0398 family.

102684:I6H76 RS01285
gene id: 102684:I6H76_RS01285
uniprot id: A0A380KM40
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

102684:I6H76 RS05515
gene id: 102684:I6H76_RS05515
uniprot id: A0A380KJN0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

102684:I6H76 RS09705
gene id: 102684:I6H76_RS09705
uniprot id: A0A380KQQ8
names: Similarity
messages: Belongs to the UPF0342 family.

102684:I6H76 RS09650
gene id: 102684:I6H76_RS09650
uniprot id: A0A380KMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

102684:I6H76 RS01520
gene id: 102684:I6H76_RS01520
uniprot id: A0A380KLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03380
gene id: 102684:I6H76_RS03380
uniprot id: A0A380KKH9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

102684:I6H76 RS09075
gene id: 102684:I6H76_RS09075
uniprot id: A0A380KQQ5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

102684:I6H76 RS03950
gene id: 102684:I6H76_RS03950
uniprot id: A0A380KL04
names: Similarity
messages: Belongs to the fabD family.

102684:I6H76 RS08780
gene id: 102684:I6H76_RS08780
uniprot id: A0A380KQX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

102684:I6H76 RS06315
gene id: 102684:I6H76_RS06315
uniprot id: A0A380KST7
names: Similarity
messages: Belongs to the TelA family.

102684:I6H76 RS08970
gene id: 102684:I6H76_RS08970
uniprot id: A0A380KQS7
names: Similarity
messages: Belongs to the peptidase C69 family.

102684:I6H76 RS02555
gene id: 102684:I6H76_RS02555
uniprot id: A0A380KNR8
names: Function
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant.

102684:I6H76 RS04510
gene id: 102684:I6H76_RS04510
uniprot id: A0A380KMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

102684:I6H76 RS06005
gene id: 102684:I6H76_RS06005
uniprot id: A0A380KPQ4
names: Similarity
messages: Belongs to the asp23 family.

102684:I6H76 RS03280
gene id: 102684:I6H76_RS03280
uniprot id: A0A380KKJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01590
gene id: 102684:I6H76_RS01590
uniprot id: A0A380KN90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

102684:I6H76 RS07625
gene id: 102684:I6H76_RS07625
uniprot id: A0A380KNX5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

102684:I6H76 RS09300
gene id: 102684:I6H76_RS09300
uniprot id: A0A380KNA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS01935
gene id: 102684:I6H76_RS01935
uniprot id: A0A380KN21
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

102684:I6H76 RS02535
gene id: 102684:I6H76_RS02535
uniprot id: A0A380KNY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03085
gene id: 102684:I6H76_RS03085
uniprot id: A0A380KL44
names: Subcellular Location Annotation
messages: Cytoplasm

102684:I6H76 RS00175
gene id: 102684:I6H76_RS00175
uniprot id: A0A380KPV6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

102684:I6H76 RS08680
gene id: 102684:I6H76_RS08680
uniprot id: A0A380KQZ3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07165
gene id: 102684:I6H76_RS07165
uniprot id: A0A380KRI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS03530
gene id: 102684:I6H76_RS03530
uniprot id: A0A380KKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

102684:I6H76 RS02320
gene id: 102684:I6H76_RS02320
uniprot id: A0A380KL62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

102684:I6H76 RS01970
gene id: 102684:I6H76_RS01970
uniprot id: A0A380KNV3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08015
gene id: 102684:I6H76_RS08015
uniprot id: A0A380KQH1
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04065
gene id: 102684:I6H76_RS04065
uniprot id: A0A380KMX7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

102684:I6H76 RS02765
gene id: 102684:I6H76_RS02765
uniprot id: A0A380KL50
names: Subunit
messages: Homodimer.

102684:I6H76 RS09880
gene id: 102684:I6H76_RS09880
uniprot id: A0A380KQ08
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS01040
gene id: 102684:I6H76_RS01040
uniprot id: A0A380KPV8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

102684:I6H76 RS09015
gene id: 102684:I6H76_RS09015
uniprot id: A0A380KQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

102684:I6H76 RS06625
gene id: 102684:I6H76_RS06625
uniprot id: A0A380KPW5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

102684:I6H76 RS08645
gene id: 102684:I6H76_RS08645
uniprot id: A0A380KND9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

102684:I6H76 RS01360
gene id: 102684:I6H76_RS01360
uniprot id: A0A380KPE6
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

102684:I6H76 RS04075
gene id: 102684:I6H76_RS04075
uniprot id: A0A380KKX4
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS02540
gene id: 102684:I6H76_RS02540
uniprot id: A0A380KMV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

102684:I6H76 RS04520
gene id: 102684:I6H76_RS04520
uniprot id: A0A0U2W973
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

102684:I6H76 RS03115
gene id: 102684:I6H76_RS03115
uniprot id: A0A380KKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS01375
gene id: 102684:I6H76_RS01375
uniprot id: A0A380KLX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

102684:I6H76 RS07960
gene id: 102684:I6H76_RS07960
uniprot id: A0A380KP10
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

102684:I6H76 RS05370
gene id: 102684:I6H76_RS05370
uniprot id: A0A380KJR3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

102684:I6H76 RS08905
gene id: 102684:I6H76_RS08905
uniprot id: A0A380KNJ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS09265
gene id: 102684:I6H76_RS09265
uniprot id: A0A380KPP2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

102684:I6H76 RS03335
gene id: 102684:I6H76_RS03335
uniprot id: A0A380KKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

102684:I6H76 RS06880
gene id: 102684:I6H76_RS06880
uniprot id: A0A380KR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

102684:I6H76 RS05350
gene id: 102684:I6H76_RS05350
uniprot id: A0A0U3DIE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

102684:I6H76 RS00930
gene id: 102684:I6H76_RS00930
uniprot id: A0A380KM57
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

102684:I6H76 RS09165
gene id: 102684:I6H76_RS09165
uniprot id: A0A380KNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

102684:I6H76 RS00640
gene id: 102684:I6H76_RS00640
uniprot id: A0A380KPV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

102684:I6H76 RS02350
gene id: 102684:I6H76_RS02350
uniprot id: A0A380KLA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

102684:I6H76 RS09150
gene id: 102684:I6H76_RS09150
uniprot id: A0A380KNE1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

102684:I6H76 RS06135
gene id: 102684:I6H76_RS06135
uniprot id: A0A380KSG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

102684:I6H76 RS09005
gene id: 102684:I6H76_RS09005
uniprot id: A0A380KPU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

102684:I6H76 RS02470
gene id: 102684:I6H76_RS02470
uniprot id: A0A380KL27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

102684:I6H76 RS07440
gene id: 102684:I6H76_RS07440
uniprot id: A0A0U2WC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04230
gene id: 102684:I6H76_RS04230
uniprot id: A0A380KLT1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

102684:I6H76 RS05900
gene id: 102684:I6H76_RS05900
uniprot id: A0A380KPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04240
gene id: 102684:I6H76_RS04240
uniprot id: A0A380KMN7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

102684:I6H76 RS02460
gene id: 102684:I6H76_RS02460
uniprot id: A0A380KMR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

102684:I6H76 RS05895
gene id: 102684:I6H76_RS05895
uniprot id: A0A380KRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

102684:I6H76 RS06485
gene id: 102684:I6H76_RS06485
uniprot id: A0A380KRV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

102684:I6H76 RS07740
gene id: 102684:I6H76_RS07740
uniprot id: A0A380KQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

102684:I6H76 RS00240
gene id: 102684:I6H76_RS00240
uniprot id: A0A380KMJ8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

102684:I6H76 RS08335
gene id: 102684:I6H76_RS08335
uniprot id: A0A380KRL1
names: Similarity
messages: Belongs to the DtxR/MntR family.

102684:I6H76 RS05470
gene id: 102684:I6H76_RS05470
uniprot id: A0A380KJF9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

102684:I6H76 RS03550
gene id: 102684:I6H76_RS03550
uniprot id: A0A380KM65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

102684:I6H76 RS08355
gene id: 102684:I6H76_RS08355
uniprot id: A0A380KR56
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

102684:I6H76 RS03060
gene id: 102684:I6H76_RS03060
uniprot id: A0A380KNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

102684:I6H76 RS09155
gene id: 102684:I6H76_RS09155
uniprot id: A0A380KR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

102684:I6H76 RS06850
gene id: 102684:I6H76_RS06850
uniprot id: A0A380KSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

102684:I6H76 RS03365
gene id: 102684:I6H76_RS03365
uniprot id: A0A380KKQ5
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

102684:I6H76 RS08675
gene id: 102684:I6H76_RS08675
uniprot id: A0A380KQP6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

102684:I6H76 RS02650
gene id: 102684:I6H76_RS02650
uniprot id: A0A380KNH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

102684:I6H76 RS09020
gene id: 102684:I6H76_RS09020
uniprot id: A0A380KQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

102684:I6H76 RS06375
gene id: 102684:I6H76_RS06375
uniprot id: A0A380KQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

102684:I6H76 RS00725
gene id: 102684:I6H76_RS00725
uniprot id: A0A380KNV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

102684:I6H76 RS08265
gene id: 102684:I6H76_RS08265
uniprot id: A0A380KQB7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

102684:I6H76 RS06075
gene id: 102684:I6H76_RS06075
uniprot id: A0A0U3E3C5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

102684:I6H76 RS07575
gene id: 102684:I6H76_RS07575
uniprot id: A0A380KNY5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

102684:I6H76 RS04265
gene id: 102684:I6H76_RS04265
uniprot id: A0A380KK27
names: Similarity
names: Subunit
messages: Belongs to the UPF0237 family.
messages: Homodimer.

102684:I6H76 RS08345
gene id: 102684:I6H76_RS08345
uniprot id: A0A380KP01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

102684:I6H76 RS01465
gene id: 102684:I6H76_RS01465
uniprot id: A0A380KLT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04565
gene id: 102684:I6H76_RS04565
uniprot id: A0A380KK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

102684:I6H76 RS04900
gene id: 102684:I6H76_RS04900
uniprot id: A0A380KMB8
names: Similarity
messages: Belongs to the aldose epimerase family.

102684:I6H76 RS07770
gene id: 102684:I6H76_RS07770
uniprot id: A0A380KNV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03645
gene id: 102684:I6H76_RS03645
uniprot id: A0A380KKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08720
gene id: 102684:I6H76_RS08720
uniprot id: A0A380KNS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

102684:I6H76 RS07570
gene id: 102684:I6H76_RS07570
uniprot id: A0A380KQR2
names: Similarity
messages: Belongs to the asp23 family.

102684:I6H76 RS02645
gene id: 102684:I6H76_RS02645
uniprot id: A0A380KLQ4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

102684:I6H76 RS00075
gene id: 102684:I6H76_RS00075
uniprot id: A0A380KP85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

102684:I6H76 RS06875
gene id: 102684:I6H76_RS06875
uniprot id: A0A380KPL2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

102684:I6H76 RS00325
gene id: 102684:I6H76_RS00325
uniprot id: A0A380KQ19
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

102684:I6H76 RS04560
gene id: 102684:I6H76_RS04560
uniprot id: A0A380KMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

102684:I6H76 RS01920
gene id: 102684:I6H76_RS01920
uniprot id: A0A380KNW0
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS05385
gene id: 102684:I6H76_RS05385
uniprot id: A0A0U3DZI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

102684:I6H76 RS06150
gene id: 102684:I6H76_RS06150
uniprot id: A0A380KPR3
names: Similarity
messages: Belongs to the CinA family.

102684:I6H76 RS05780
gene id: 102684:I6H76_RS05780
uniprot id: A0A380KJI3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

102684:I6H76 RS00285
gene id: 102684:I6H76_RS00285
uniprot id: A0A380KP19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

102684:I6H76 RS09110
gene id: 102684:I6H76_RS09110
uniprot id: A0A380KPS3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09690
gene id: 102684:I6H76_RS09690
uniprot id: A0A380KMU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

102684:I6H76 RS00190
gene id: 102684:I6H76_RS00190
uniprot id: A0A380KP38
names: Cofactor
messages: Binds 1 zinc ion per subunit.

102684:I6H76 RS07700
gene id: 102684:I6H76_RS07700
uniprot id: A0A380KPB7
names: Similarity
messages: Belongs to the EamA transporter family.

102684:I6H76 RS07535
gene id: 102684:I6H76_RS07535
uniprot id: A0A380KNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

102684:I6H76 RS03535
gene id: 102684:I6H76_RS03535
uniprot id: A0A0U3FBD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

102684:I6H76 RS08380
gene id: 102684:I6H76_RS08380
uniprot id: A0A380KNX9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

102684:I6H76 RS00625
gene id: 102684:I6H76_RS00625
uniprot id: A0A380KNX3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09935
gene id: 102684:I6H76_RS09935
uniprot id: A0A380KQ89
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

102684:I6H76 RS00510
gene id: 102684:I6H76_RS00510
uniprot id: A0A380KM69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

102684:I6H76 RS08240
gene id: 102684:I6H76_RS08240
uniprot id: A0A380KQB4
names: Similarity
messages: Belongs to the P(II) protein family.

102684:I6H76 RS06355
gene id: 102684:I6H76_RS06355
uniprot id: A0A380KQ62
names: Similarity
messages: Belongs to the Fur family.

102684:I6H76 RS03930
gene id: 102684:I6H76_RS03930
uniprot id: A0A380KK79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

102684:I6H76 RS02735
gene id: 102684:I6H76_RS02735
uniprot id: A0A380KMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

102684:I6H76 RS00660
gene id: 102684:I6H76_RS00660
uniprot id: A0A380KM38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

102684:I6H76 RS09145
gene id: 102684:I6H76_RS09145
uniprot id: A0A380KMY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

102684:I6H76 RS09235
gene id: 102684:I6H76_RS09235
uniprot id: A0A380KPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

102684:I6H76 RS03240
gene id: 102684:I6H76_RS03240
uniprot id: A0A380KNG4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

102684:I6H76 RS00355
gene id: 102684:I6H76_RS00355
uniprot id: A0A380KPS1
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08155
gene id: 102684:I6H76_RS08155
uniprot id: A0A380KRB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

102684:I6H76 RS09770
gene id: 102684:I6H76_RS09770
uniprot id: A0A380KQ28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

102684:I6H76 RS09295
gene id: 102684:I6H76_RS09295
uniprot id: A0A380KMV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS03610
gene id: 102684:I6H76_RS03610
uniprot id: A0A380KL74
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

102684:I6H76 RS09240
gene id: 102684:I6H76_RS09240
uniprot id: A0A380KN27
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

102684:I6H76 RS05950
gene id: 102684:I6H76_RS05950
uniprot id: A0A380KPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

102684:I6H76 RS00130
gene id: 102684:I6H76_RS00130
uniprot id: A0A380KPW6
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

102684:I6H76 RS02930
gene id: 102684:I6H76_RS02930
uniprot id: A0A380KMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

102684:I6H76 RS08785
gene id: 102684:I6H76_RS08785
uniprot id: A0A380KNG8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

102684:I6H76 RS02395
gene id: 102684:I6H76_RS02395
uniprot id: A0A380KNV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS06480
gene id: 102684:I6H76_RS06480
uniprot id: A0A380KPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

102684:I6H76 RS05860
gene id: 102684:I6H76_RS05860
uniprot id: A0A380KQF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

102684:I6H76 RS00920
gene id: 102684:I6H76_RS00920
uniprot id: A0A380KPF2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

102684:I6H76 RS04025
gene id: 102684:I6H76_RS04025
uniprot id: A0A380KKY9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

102684:I6H76 RS04725
gene id: 102684:I6H76_RS04725
uniprot id: A0A380KJT1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

102684:I6H76 RS05910
gene id: 102684:I6H76_RS05910
uniprot id: A0A380KQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

102684:I6H76 RS03940
gene id: 102684:I6H76_RS03940
uniprot id: A0A380KN00
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

102684:I6H76 RS08755
gene id: 102684:I6H76_RS08755
uniprot id: A0A380KNM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS08685
gene id: 102684:I6H76_RS08685
uniprot id: A0A380KNJ1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

102684:I6H76 RS08135
gene id: 102684:I6H76_RS08135
uniprot id: A0A380KRR3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04700
gene id: 102684:I6H76_RS04700
uniprot id: A0A380KMF4
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

102684:I6H76 RS01265
gene id: 102684:I6H76_RS01265
uniprot id: A0A380KLX7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

102684:I6H76 RS03025
gene id: 102684:I6H76_RS03025
uniprot id: A0A380KKR0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

102684:I6H76 RS00990
gene id: 102684:I6H76_RS00990
uniprot id: A0A380KPW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

102684:I6H76 RS04635
gene id: 102684:I6H76_RS04635
uniprot id: A0A380KMK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

102684:I6H76 RS00025
gene id: 102684:I6H76_RS00025
uniprot id: A0A380KPA3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

102684:I6H76 RS02510
gene id: 102684:I6H76_RS02510
uniprot id: A0A380KL77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

102684:I6H76 RS03975
gene id: 102684:I6H76_RS03975
uniprot id: A0A380KKH4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

102684:I6H76 RS00145
gene id: 102684:I6H76_RS00145
uniprot id: A0A380KP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

102684:I6H76 RS03475
gene id: 102684:I6H76_RS03475
uniprot id: A0A380KM92
names: Similarity
messages: Belongs to the IMPACT family.

102684:I6H76 RS08660
gene id: 102684:I6H76_RS08660
uniprot id: A0A380KRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05940
gene id: 102684:I6H76_RS05940
uniprot id: A0A380KQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

102684:I6H76 RS04585
gene id: 102684:I6H76_RS04585
uniprot id: A0A380KKB7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

102684:I6H76 RS03510
gene id: 102684:I6H76_RS03510
uniprot id: A0A380KN20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06410
gene id: 102684:I6H76_RS06410
uniprot id: A0A380KPI0
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

102684:I6H76 RS02660
gene id: 102684:I6H76_RS02660
uniprot id: A0A380KL45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

102684:I6H76 RS02475
gene id: 102684:I6H76_RS02475
uniprot id: A0A380KLF4
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

102684:I6H76 RS01740
gene id: 102684:I6H76_RS01740
uniprot id: A0A380KLN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

102684:I6H76 RS07865
gene id: 102684:I6H76_RS07865
uniprot id: A0A380KQJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05120
gene id: 102684:I6H76_RS05120
uniprot id: A0A380KJL0
names: Similarity
messages: Belongs to the GSP E family.

102684:I6H76 RS04120
gene id: 102684:I6H76_RS04120
uniprot id: A0A380KMW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS00090
gene id: 102684:I6H76_RS00090
uniprot id: A0A380KMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS00260
gene id: 102684:I6H76_RS00260
uniprot id: A0A380KP45
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

102684:I6H76 RS06775
gene id: 102684:I6H76_RS06775
uniprot id: A0A380KR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

102684:I6H76 RS08615
gene id: 102684:I6H76_RS08615
uniprot id: A0A380KQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

102684:I6H76 RS09035
gene id: 102684:I6H76_RS09035
uniprot id: A0A380KN64
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09435
gene id: 102684:I6H76_RS09435
uniprot id: A0A380KQ97
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

102684:I6H76 RS06430
gene id: 102684:I6H76_RS06430
uniprot id: A0A380KQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

102684:I6H76 RS00870
gene id: 102684:I6H76_RS00870
uniprot id: A0A380KPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

102684:I6H76 RS00775
gene id: 102684:I6H76_RS00775
uniprot id: A0A380KNU6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

102684:I6H76 RS06930
gene id: 102684:I6H76_RS06930
uniprot id: A0A380KP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

102684:I6H76 RS07235
gene id: 102684:I6H76_RS07235
uniprot id: A0A380KP00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

102684:I6H76 RS08175
gene id: 102684:I6H76_RS08175
uniprot id: A0A380KNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

102684:I6H76 RS03755
gene id: 102684:I6H76_RS03755
uniprot id: A0A380KMX6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

102684:I6H76 RS05025
gene id: 102684:I6H76_RS05025
uniprot id: A0A380KK33
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

102684:I6H76 RS02690
gene id: 102684:I6H76_RS02690
uniprot id: A0A380KMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

102684:I6H76 RS00465
gene id: 102684:I6H76_RS00465
uniprot id: A0A380KMK2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS06905
gene id: 102684:I6H76_RS06905
uniprot id: A0A380KRM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS00365
gene id: 102684:I6H76_RS00365
uniprot id: A0A380KMG8
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS03925
gene id: 102684:I6H76_RS03925
uniprot id: A0A380KKI2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

102684:I6H76 RS03460
gene id: 102684:I6H76_RS03460
uniprot id: A0A380KN29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

102684:I6H76 RS04080
gene id: 102684:I6H76_RS04080
uniprot id: A0A380KMR6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

102684:I6H76 RS04505
gene id: 102684:I6H76_RS04505
uniprot id: A0A380KMJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

102684:I6H76 RS05855
gene id: 102684:I6H76_RS05855
uniprot id: A0A380KPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS01700
gene id: 102684:I6H76_RS01700
uniprot id: A0A380KLQ8
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07420
gene id: 102684:I6H76_RS07420
uniprot id: A0A380KRQ5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

102684:I6H76 RS05015
gene id: 102684:I6H76_RS05015
uniprot id: A0A380KJV9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

102684:I6H76 RS05410
gene id: 102684:I6H76_RS05410
uniprot id: A0A380KJM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

102684:I6H76 RS05130
gene id: 102684:I6H76_RS05130
uniprot id: A0A380KM98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

102684:I6H76 RS02935
gene id: 102684:I6H76_RS02935
uniprot id: A0A380KLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

102684:I6H76 RS07935
gene id: 102684:I6H76_RS07935
uniprot id: A0A380KRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

102684:I6H76 RS07990
gene id: 102684:I6H76_RS07990
uniprot id: A0A380KQG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerD-like subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.

102684:I6H76 RS02015
gene id: 102684:I6H76_RS02015
uniprot id: A0A380KM19
names: Similarity
messages: Belongs to the peptidase C40 family.

102684:I6H76 RS08875
gene id: 102684:I6H76_RS08875
uniprot id: A0A380KQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

102684:I6H76 RS08955
gene id: 102684:I6H76_RS08955
uniprot id: A0A380KPV4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

102684:I6H76 RS09125
gene id: 102684:I6H76_RS09125
uniprot id: A0A380KQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

102684:I6H76 RS07955
gene id: 102684:I6H76_RS07955
uniprot id: A0A380KRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

102684:I6H76 RS06285
gene id: 102684:I6H76_RS06285
uniprot id: A0A380KSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

102684:I6H76 RS02580
gene id: 102684:I6H76_RS02580
uniprot id: A0A380KLD3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09315
gene id: 102684:I6H76_RS09315
uniprot id: A0A380KNF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

102684:I6H76 RS03040
gene id: 102684:I6H76_RS03040
uniprot id: A0A0U2M1M9
names: Similarity
messages: Belongs to the YggT family.

102684:I6H76 RS00140
gene id: 102684:I6H76_RS00140
uniprot id: A0A380KMM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS01910
gene id: 102684:I6H76_RS01910
uniprot id: A0A380KN75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08340
gene id: 102684:I6H76_RS08340
uniprot id: A0A380KQ92
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

102684:I6H76 RS02495
gene id: 102684:I6H76_RS02495
uniprot id: A0A380KNJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

102684:I6H76 RS01340
gene id: 102684:I6H76_RS01340
uniprot id: A0A380KPM5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

102684:I6H76 RS05145
gene id: 102684:I6H76_RS05145
uniprot id: A0A380KM72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS09655
gene id: 102684:I6H76_RS09655
uniprot id: A0A380KN28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

102684:I6H76 RS03545
gene id: 102684:I6H76_RS03545
uniprot id: A0A380KNA2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

102684:I6H76 RS04915
gene id: 102684:I6H76_RS04915
uniprot id: A0A380KLE5
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07695
gene id: 102684:I6H76_RS07695
uniprot id: A0A380KQL5
names: Similarity
messages: Belongs to the EamA transporter family.

102684:I6H76 RS02950
gene id: 102684:I6H76_RS02950
uniprot id: A0A380KKZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

102684:I6H76 RS09710
gene id: 102684:I6H76_RS09710
uniprot id: A0A380KPE9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

102684:I6H76 RS03985
gene id: 102684:I6H76_RS03985
uniprot id: A0A380KKM8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

102684:I6H76 RS06420
gene id: 102684:I6H76_RS06420
uniprot id: A0A380KSR8
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS01390
gene id: 102684:I6H76_RS01390
uniprot id: A0A380KPL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS07655
gene id: 102684:I6H76_RS07655
uniprot id: A0A380KR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

102684:I6H76 RS09505
gene id: 102684:I6H76_RS09505
uniprot id: A0A380KN63
names: Similarity
messages: Belongs to the disproportionating enzyme family.

102684:I6H76 RS04235
gene id: 102684:I6H76_RS04235
uniprot id: A0A380KKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

102684:I6H76 RS08835
gene id: 102684:I6H76_RS08835
uniprot id: A0A380KNF1
names: Similarity
messages: Belongs to the FemABX family.

102684:I6H76 RS01980
gene id: 102684:I6H76_RS01980
uniprot id: A0A380KLI8
names: Similarity
messages: Belongs to the TPP enzyme family.

102684:I6H76 RS00105
gene id: 102684:I6H76_RS00105
uniprot id: A0A380KMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06000
gene id: 102684:I6H76_RS06000
uniprot id: A0A380KPT6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

102684:I6H76 RS09045
gene id: 102684:I6H76_RS09045
uniprot id: A0A380KNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09800
gene id: 102684:I6H76_RS09800
uniprot id: A0A380KMZ4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03055
gene id: 102684:I6H76_RS03055
uniprot id: A0A380KNA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

102684:I6H76 RS05535
gene id: 102684:I6H76_RS05535
uniprot id: A0A380KL25
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS08420
gene id: 102684:I6H76_RS08420
uniprot id: A0A380KRI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS02965
gene id: 102684:I6H76_RS02965
uniprot id: A0A380KL11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

102684:I6H76 RS04790
gene id: 102684:I6H76_RS04790
uniprot id: A0A380KKH5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

102684:I6H76 RS01690
gene id: 102684:I6H76_RS01690
uniprot id: A0A380KLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

102684:I6H76 RS03185
gene id: 102684:I6H76_RS03185
uniprot id: A0A380KL20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

102684:I6H76 RS07325
gene id: 102684:I6H76_RS07325
uniprot id: A0A380KQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

102684:I6H76 RS05325
gene id: 102684:I6H76_RS05325
uniprot id: A0A380KJJ1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

102684:I6H76 RS06070
gene id: 102684:I6H76_RS06070
uniprot id: A0A0U2TWL6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

102684:I6H76 RS09490
gene id: 102684:I6H76_RS09490
uniprot id: A0A380KPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS02815
gene id: 102684:I6H76_RS02815
uniprot id: A0A380KKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

102684:I6H76 RS00010
gene id: 102684:I6H76_RS00010
uniprot id: A0A380KMH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

102684:I6H76 RS04810
gene id: 102684:I6H76_RS04810
uniprot id: A0A380KLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

102684:I6H76 RS01825
gene id: 102684:I6H76_RS01825
uniprot id: A0A0U3EX20
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08585
gene id: 102684:I6H76_RS08585
uniprot id: A0A380KNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04750
gene id: 102684:I6H76_RS04750
uniprot id: A0A380KME3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

102684:I6H76 RS07970
gene id: 102684:I6H76_RS07970
uniprot id: A0A380KNR9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

102684:I6H76 RS07585
gene id: 102684:I6H76_RS07585
uniprot id: A0A380KPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

102684:I6H76 RS00525
gene id: 102684:I6H76_RS00525
uniprot id: A0A380KNZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

102684:I6H76 RS08005
gene id: 102684:I6H76_RS08005
uniprot id: A0A380KRE4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

102684:I6H76 RS04610
gene id: 102684:I6H76_RS04610
uniprot id: A0A380KK13
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

102684:I6H76 RS01600
gene id: 102684:I6H76_RS01600
uniprot id: A0A380KLJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09170
gene id: 102684:I6H76_RS09170
uniprot id: A0A380KQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

102684:I6H76 RS09900
gene id: 102684:I6H76_RS09900
uniprot id: A0A380KMQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09755
gene id: 102684:I6H76_RS09755
uniprot id: A0A0U2V193
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

102684:I6H76 RS03705
gene id: 102684:I6H76_RS03705
uniprot id: A0A380KM33
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

102684:I6H76 RS08470
gene id: 102684:I6H76_RS08470
uniprot id: A0A380KRH7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

102684:I6H76 RS04535
gene id: 102684:I6H76_RS04535
uniprot id: A0A380KKC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

102684:I6H76 RS05805
gene id: 102684:I6H76_RS05805
uniprot id: A0A380KT34
names: Similarity
messages: Belongs to the ParB family.

102684:I6H76 RS05775
gene id: 102684:I6H76_RS05775
uniprot id: A0A380KM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

102684:I6H76 RS08830
gene id: 102684:I6H76_RS08830
uniprot id: A0A380KQW5
names: Similarity
messages: Belongs to the FemABX family.

102684:I6H76 RS09670
gene id: 102684:I6H76_RS09670
uniprot id: A0A380KQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06110
gene id: 102684:I6H76_RS06110
uniprot id: A0A380KQB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS08455
gene id: 102684:I6H76_RS08455
uniprot id: A0A0U3F8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

102684:I6H76 RS04490
gene id: 102684:I6H76_RS04490
uniprot id: A0A380KMN8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS05365
gene id: 102684:I6H76_RS05365
uniprot id: A0A0U3FCE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

102684:I6H76 RS04450
gene id: 102684:I6H76_RS04450
uniprot id: A0A380KKP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

102684:I6H76 RS06020
gene id: 102684:I6H76_RS06020
uniprot id: A0A380KRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

102684:I6H76 RS09140
gene id: 102684:I6H76_RS09140
uniprot id: A0A380KN43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

102684:I6H76 RS09230
gene id: 102684:I6H76_RS09230
uniprot id: A0A380KN69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

102684:I6H76 RS03050
gene id: 102684:I6H76_RS03050
uniprot id: A0A380KLI1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

102684:I6H76 RS09205
gene id: 102684:I6H76_RS09205
uniprot id: A0A380KR10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

102684:I6H76 RS00110
gene id: 102684:I6H76_RS00110
uniprot id: A0A380KMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06365
gene id: 102684:I6H76_RS06365
uniprot id: A0A380KRA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

102684:I6H76 RS01480
gene id: 102684:I6H76_RS01480
uniprot id: A0A380KLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04800
gene id: 102684:I6H76_RS04800
uniprot id: A0A380KMJ6
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS03870
gene id: 102684:I6H76_RS03870
uniprot id: A0A380KM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06870
gene id: 102684:I6H76_RS06870
uniprot id: A0A380KS14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

102684:I6H76 RS09420
gene id: 102684:I6H76_RS09420
uniprot id: A0A380KQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

102684:I6H76 RS03170
gene id: 102684:I6H76_RS03170
uniprot id: A0A380KME7
names: Similarity
messages: Belongs to the TrpC family.

102684:I6H76 RS08375
gene id: 102684:I6H76_RS08375
uniprot id: A0A380KNE2
names: Similarity
messages: Belongs to the CvfB family.

102684:I6H76 RS01495
gene id: 102684:I6H76_RS01495
uniprot id: A0A380KNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

102684:I6H76 RS02525
gene id: 102684:I6H76_RS02525
uniprot id: A0A380KL17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

102684:I6H76 RS05320
gene id: 102684:I6H76_RS05320
uniprot id: A0A0U3FDX4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS09780
gene id: 102684:I6H76_RS09780
uniprot id: A0A380KMU0
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

102684:I6H76 RS08070
gene id: 102684:I6H76_RS08070
uniprot id: A0A380KNP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

102684:I6H76 RS04245
gene id: 102684:I6H76_RS04245
uniprot id: A0A380KMV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

102684:I6H76 RS08030
gene id: 102684:I6H76_RS08030
uniprot id: A0A380KP72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

102684:I6H76 RS03700
gene id: 102684:I6H76_RS03700
uniprot id: A0A0U3FBA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

102684:I6H76 RS05110
gene id: 102684:I6H76_RS05110
uniprot id: A0A380KLA6
names: Function
messages: Required for transformation and DNA binding.

102684:I6H76 RS02560
gene id: 102684:I6H76_RS02560
uniprot id: A0A380KL66
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

102684:I6H76 RS02990
gene id: 102684:I6H76_RS02990
uniprot id: A0A380KLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

102684:I6H76 RS00390
gene id: 102684:I6H76_RS00390
uniprot id: A0A380KP18
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS00270
gene id: 102684:I6H76_RS00270
uniprot id: A0A380KPT8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

102684:I6H76 RS06175
gene id: 102684:I6H76_RS06175
uniprot id: A0A380KQ53
names: Similarity
messages: Belongs to the UPF0473 family.

102684:I6H76 RS07390
gene id: 102684:I6H76_RS07390
uniprot id: A0A380KNW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

102684:I6H76 RS00695
gene id: 102684:I6H76_RS00695
uniprot id: A0A380KMA7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

102684:I6H76 RS01810
gene id: 102684:I6H76_RS01810
uniprot id: A0A380KLU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

102684:I6H76 RS02820
gene id: 102684:I6H76_RS02820
uniprot id: A0A380KL87
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04695
gene id: 102684:I6H76_RS04695
uniprot id: A0A380KKJ4
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

102684:I6H76 RS03640
gene id: 102684:I6H76_RS03640
uniprot id: A0A380KKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07180
gene id: 102684:I6H76_RS07180
uniprot id: A0A380KQY9
names: Similarity
messages: Belongs to the glutamine synthetase family.

102684:I6H76 RS05850
gene id: 102684:I6H76_RS05850
uniprot id: A0A380KPW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09175
gene id: 102684:I6H76_RS09175
uniprot id: A0A380KQN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS07835
gene id: 102684:I6H76_RS07835
uniprot id: A0A380KRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

102684:I6H76 RS09575
gene id: 102684:I6H76_RS09575
uniprot id: A0A380KQ68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

102684:I6H76 RS02250
gene id: 102684:I6H76_RS02250
uniprot id: A0A380KNX8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

102684:I6H76 RS06865
gene id: 102684:I6H76_RS06865
uniprot id: A0A380KRN1
names: Similarity
messages: Belongs to the DltD family.

102684:I6H76 RS05965
gene id: 102684:I6H76_RS05965
uniprot id: A0A380KT02
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

102684:I6H76 RS04625
gene id: 102684:I6H76_RS04625
uniprot id: A0A0U3DW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05740
gene id: 102684:I6H76_RS05740
uniprot id: A0A380KJE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

102684:I6H76 RS08385
gene id: 102684:I6H76_RS08385
uniprot id: A0A0U3FGU9
names: Similarity
messages: Belongs to the UPF0346 family.

102684:I6H76 RS08915
gene id: 102684:I6H76_RS08915
uniprot id: A0A380KPW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS01800
gene id: 102684:I6H76_RS01800
uniprot id: A0A380KLN7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

102684:I6H76 RS07000
gene id: 102684:I6H76_RS07000
uniprot id: A0A380KRK4
names: Similarity
messages: Belongs to the UPF0177 family.

102684:I6H76 RS09310
gene id: 102684:I6H76_RS09310
uniprot id: A0A380KPN1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

102684:I6H76 RS04195
gene id: 102684:I6H76_RS04195
uniprot id: A0A380KMP7
names: Similarity
messages: Belongs to the UPF0340 family.

102684:I6H76 RS02655
gene id: 102684:I6H76_RS02655
uniprot id: A0A380KNQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

102684:I6H76 RS07160
gene id: 102684:I6H76_RS07160
uniprot id: A0A380KPL5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

102684:I6H76 RS07995
gene id: 102684:I6H76_RS07995
uniprot id: A0A380KP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

102684:I6H76 RS07860
gene id: 102684:I6H76_RS07860
uniprot id: A0A0U3F979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

102684:I6H76 RS00475
gene id: 102684:I6H76_RS00475
uniprot id: A0A380KNZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

102684:I6H76 RS03350
gene id: 102684:I6H76_RS03350
uniprot id: A0A380KLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03100
gene id: 102684:I6H76_RS03100
uniprot id: A0A380KLH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS06230
gene id: 102684:I6H76_RS06230
uniprot id: A0A380KRZ8
names: Similarity
messages: Belongs to the peptidase M13 family.

102684:I6H76 RS00205
gene id: 102684:I6H76_RS00205
uniprot id: A0A380KMS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

102684:I6H76 RS07320
gene id: 102684:I6H76_RS07320
uniprot id: A0A380KPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07430
gene id: 102684:I6H76_RS07430
uniprot id: A0A654MBE4
names: Similarity
messages: Belongs to the thioredoxin family.

102684:I6H76 RS01950
gene id: 102684:I6H76_RS01950
uniprot id: A0A380KLR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS10020
gene id: 102684:I6H76_RS10020
uniprot id: A0A380KNW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01975
gene id: 102684:I6H76_RS01975
uniprot id: A0A380KP31
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

102684:I6H76 RS07825
gene id: 102684:I6H76_RS07825
uniprot id: A0A380KNP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

102684:I6H76 RS02440
gene id: 102684:I6H76_RS02440
uniprot id: A0A0U3EWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

102684:I6H76 RS02595
gene id: 102684:I6H76_RS02595
uniprot id: A0A380KLR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

102684:I6H76 RS09680
gene id: 102684:I6H76_RS09680
uniprot id: A0A380KMW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS02410
gene id: 102684:I6H76_RS02410
uniprot id: A0A380KLB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

102684:I6H76 RS06825
gene id: 102684:I6H76_RS06825
uniprot id: A0A380KPM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

102684:I6H76 RS03605
gene id: 102684:I6H76_RS03605
uniprot id: A0A380KM54
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

102684:I6H76 RS07400
gene id: 102684:I6H76_RS07400
uniprot id: A0A380KS58
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS06310
gene id: 102684:I6H76_RS06310
uniprot id: A0A380KQ71
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

102684:I6H76 RS04665
gene id: 102684:I6H76_RS04665
uniprot id: A0A380KLJ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08035
gene id: 102684:I6H76_RS08035
uniprot id: A0A380KRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

102684:I6H76 RS08150
gene id: 102684:I6H76_RS08150
uniprot id: A0A380KR11
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

102684:I6H76 RS02925
gene id: 102684:I6H76_RS02925
uniprot id: A0A380KNN7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

102684:I6H76 RS07385
gene id: 102684:I6H76_RS07385
uniprot id: A0A380KP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03715
gene id: 102684:I6H76_RS03715
uniprot id: A0A380KKJ5
names: Subcellular Location Annotation
messages: Secreted

102684:I6H76 RS04835
gene id: 102684:I6H76_RS04835
uniprot id: A0A380KKG6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

102684:I6H76 RS08580
gene id: 102684:I6H76_RS08580
uniprot id: A0A380KR12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08290
gene id: 102684:I6H76_RS08290
uniprot id: A0A380KQA3
names: Similarity
messages: Belongs to the FemABX family.

102684:I6H76 RS08225
gene id: 102684:I6H76_RS08225
uniprot id: A0A380KNG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

102684:I6H76 RS09070
gene id: 102684:I6H76_RS09070
uniprot id: A0A380KQG8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS06340
gene id: 102684:I6H76_RS06340
uniprot id: A0A380KRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS02955
gene id: 102684:I6H76_RS02955
uniprot id: A0A380KMI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS04150
gene id: 102684:I6H76_RS04150
uniprot id: A0A380KLU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

102684:I6H76 RS04880
gene id: 102684:I6H76_RS04880
uniprot id: A0A380KK62
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS07555
gene id: 102684:I6H76_RS07555
uniprot id: A0A380KRB1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

102684:I6H76 RS09200
gene id: 102684:I6H76_RS09200
uniprot id: A0A380KNC5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

102684:I6H76 RS02295
gene id: 102684:I6H76_RS02295
uniprot id: A0A380KNN4
names: Similarity
messages: Belongs to the peptidase C59 family.

102684:I6H76 RS08000
gene id: 102684:I6H76_RS08000
uniprot id: A0A380KR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

102684:I6H76 RS01570
gene id: 102684:I6H76_RS01570
uniprot id: A0A380KMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

102684:I6H76 RS01050
gene id: 102684:I6H76_RS01050
uniprot id: A0A380KMJ3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

102684:I6H76 RS05505
gene id: 102684:I6H76_RS05505
uniprot id: A0A380KJK0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS06395
gene id: 102684:I6H76_RS06395
uniprot id: A0A380KPV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09895
gene id: 102684:I6H76_RS09895
uniprot id: A0A380KPB9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

102684:I6H76 RS01305
gene id: 102684:I6H76_RS01305
uniprot id: A0A380KP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

102684:I6H76 RS09815
gene id: 102684:I6H76_RS09815
uniprot id: A0A380KN71
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS00515
gene id: 102684:I6H76_RS00515
uniprot id: A0A380KMI8
names: Similarity
messages: Belongs to the ThiD family.

102684:I6H76 RS07900
gene id: 102684:I6H76_RS07900
uniprot id: A0A380KR52
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

102684:I6H76 RS01710
gene id: 102684:I6H76_RS01710
uniprot id: A0A380KLW4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

102684:I6H76 RS08095
gene id: 102684:I6H76_RS08095
uniprot id: A0A380KP52
names: Similarity
messages: Belongs to the UPF0246 family.

102684:I6H76 RS03130
gene id: 102684:I6H76_RS03130
uniprot id: A0A380KKN9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

102684:I6H76 RS02260
gene id: 102684:I6H76_RS02260
uniprot id: A0A380KMV7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

102684:I6H76 RS00955
gene id: 102684:I6H76_RS00955
uniprot id: A0A380KPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

102684:I6H76 RS09160
gene id: 102684:I6H76_RS09160
uniprot id: A0A380KPR2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

102684:I6H76 RS01605
gene id: 102684:I6H76_RS01605
uniprot id: A0A380KLY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

102684:I6H76 RS04130
gene id: 102684:I6H76_RS04130
uniprot id: A0A380KKW3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

102684:I6H76 RS01190
gene id: 102684:I6H76_RS01190
uniprot id: A0A380KPS4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

102684:I6H76 RS01525
gene id: 102684:I6H76_RS01525
uniprot id: A0A380KN98
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07030
gene id: 102684:I6H76_RS07030
uniprot id: A0A380KP32
names: Similarity
messages: Belongs to the bacteriocin class IIA/YGNGV family.

102684:I6H76 RS02605
gene id: 102684:I6H76_RS02605
uniprot id: A0A380KNR0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

102684:I6H76 RS04180
gene id: 102684:I6H76_RS04180
uniprot id: A0A380KMV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

102684:I6H76 RS04755
gene id: 102684:I6H76_RS04755
uniprot id: A0A380KMK9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

102684:I6H76 RS00295
gene id: 102684:I6H76_RS00295
uniprot id: A0A380KMB9
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS01430
gene id: 102684:I6H76_RS01430
uniprot id: A0A380KLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

102684:I6H76 RS02520
gene id: 102684:I6H76_RS02520
uniprot id: A0A380KL90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

102684:I6H76 RS08475
gene id: 102684:I6H76_RS08475
uniprot id: A0A380KQ60
names: Similarity
messages: Belongs to the nitroreductase family.

102684:I6H76 RS04495
gene id: 102684:I6H76_RS04495
uniprot id: A0A380KLM3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

102684:I6H76 RS03900
gene id: 102684:I6H76_RS03900
uniprot id: A0A380KL10
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09270
gene id: 102684:I6H76_RS09270
uniprot id: A0A0U3EWH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

102684:I6H76 RS08285
gene id: 102684:I6H76_RS08285
uniprot id: A0A380KRM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS04360
gene id: 102684:I6H76_RS04360
uniprot id: A0A380KMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

102684:I6H76 RS08130
gene id: 102684:I6H76_RS08130
uniprot id: A0A380KP47
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09715
gene id: 102684:I6H76_RS09715
uniprot id: A0A380KN89
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

102684:I6H76 RS02545
gene id: 102684:I6H76_RS02545
uniprot id: A0A380KLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

102684:I6H76 RS00035
gene id: 102684:I6H76_RS00035
uniprot id: A0A380KPY6
names: Similarity
messages: Belongs to the polypeptide deformylase family.

102684:I6H76 RS05390
gene id: 102684:I6H76_RS05390
uniprot id: A0A380KL56
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

102684:I6H76 RS04125
gene id: 102684:I6H76_RS04125
uniprot id: A0A380KLU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

102684:I6H76 RS00790
gene id: 102684:I6H76_RS00790
uniprot id: A0A380KPS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

102684:I6H76 RS04145
gene id: 102684:I6H76_RS04145
uniprot id: A0A380KKB6
names: Similarity
messages: Belongs to the asp23 family.

102684:I6H76 RS04185
gene id: 102684:I6H76_RS04185
uniprot id: A0A380KLT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

102684:I6H76 RS01385
gene id: 102684:I6H76_RS01385
uniprot id: A0A380KM22
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

102684:I6H76 RS01255
gene id: 102684:I6H76_RS01255
uniprot id: A0A380KP89
names: Similarity
messages: Belongs to the EamA transporter family.

102684:I6H76 RS08895
gene id: 102684:I6H76_RS08895
uniprot id: A0A380KN93
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

102684:I6H76 RS01095
gene id: 102684:I6H76_RS01095
uniprot id: A0A380KNN5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

102684:I6H76 RS06130
gene id: 102684:I6H76_RS06130
uniprot id: A0A380KS17
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

102684:I6H76 RS05050
gene id: 102684:I6H76_RS05050
uniprot id: A0A380KME9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

102684:I6H76 RS01610
gene id: 102684:I6H76_RS01610
uniprot id: A0A380KPF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

102684:I6H76 RS09470
gene id: 102684:I6H76_RS09470
uniprot id: A0A380KNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08935
gene id: 102684:I6H76_RS08935
uniprot id: A0A380KND1
names: Similarity
messages: Belongs to the RutC family.

102684:I6H76 RS05280
gene id: 102684:I6H76_RS05280
uniprot id: A0A380KK12
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

102684:I6H76 RS09525
gene id: 102684:I6H76_RS09525
uniprot id: A0A380KQ79
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS05530
gene id: 102684:I6H76_RS05530
uniprot id: A0A380KM35
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

102684:I6H76 RS04685
gene id: 102684:I6H76_RS04685
uniprot id: A0A380KMJ1
names: Similarity
messages: Belongs to the aldolase LacD family.

102684:I6H76 RS07730
gene id: 102684:I6H76_RS07730
uniprot id: A0A380KPC8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

102684:I6H76 RS07495
gene id: 102684:I6H76_RS07495
uniprot id: A0A0U3EZ35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

102684:I6H76 RS03525
gene id: 102684:I6H76_RS03525
uniprot id: A0A380KM81
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

102684:I6H76 RS09865
gene id: 102684:I6H76_RS09865
uniprot id: A0A380KQM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

102684:I6H76 RS09910
gene id: 102684:I6H76_RS09910
uniprot id: A0A380KMX5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

102684:I6H76 RS05485
gene id: 102684:I6H76_RS05485
uniprot id: A0A380KL37
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

102684:I6H76 RS06465
gene id: 102684:I6H76_RS06465
uniprot id: A0A380KQ38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS07925
gene id: 102684:I6H76_RS07925
uniprot id: A0A380KNM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

102684:I6H76 RS01355
gene id: 102684:I6H76_RS01355
uniprot id: A0A380KP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS02425
gene id: 102684:I6H76_RS02425
uniprot id: A0A380KP02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

102684:I6H76 RS02415
gene id: 102684:I6H76_RS02415
uniprot id: A0A380KL40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

102684:I6H76 RS02620
gene id: 102684:I6H76_RS02620
uniprot id: A0A380KL75
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

102684:I6H76 RS05935
gene id: 102684:I6H76_RS05935
uniprot id: A0A380KSJ5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

102684:I6H76 RS08140
gene id: 102684:I6H76_RS08140
uniprot id: A0A380KQD4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

102684:I6H76 RS02485
gene id: 102684:I6H76_RS02485
uniprot id: A0A380KMW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS07830
gene id: 102684:I6H76_RS07830
uniprot id: A0A380KPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

102684:I6H76 RS05295
gene id: 102684:I6H76_RS05295
uniprot id: A0A0U3EPD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

102684:I6H76 RS02740
gene id: 102684:I6H76_RS02740
uniprot id: A0A380KLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

102684:I6H76 RS01140
gene id: 102684:I6H76_RS01140
uniprot id: A0A380KPT5
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04455
gene id: 102684:I6H76_RS04455
uniprot id: A0A380KMK0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

102684:I6H76 RS08965
gene id: 102684:I6H76_RS08965
uniprot id: A0A380KQI7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

102684:I6H76 RS02980
gene id: 102684:I6H76_RS02980
uniprot id: A0A380KNM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04550
gene id: 102684:I6H76_RS04550
uniprot id: A0A380KKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

102684:I6H76 RS09775
gene id: 102684:I6H76_RS09775
uniprot id: A0A380KQB9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

102684:I6H76 RS02385
gene id: 102684:I6H76_RS02385
uniprot id: A0A380KLV6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

102684:I6H76 RS00915
gene id: 102684:I6H76_RS00915
uniprot id: A0A380KML7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

102684:I6H76 RS02325
gene id: 102684:I6H76_RS02325
uniprot id: A0A380KLI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS07500
gene id: 102684:I6H76_RS07500
uniprot id: A0A380KS38
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

102684:I6H76 RS05285
gene id: 102684:I6H76_RS05285
uniprot id: A0A380KM85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

102684:I6H76 RS02745
gene id: 102684:I6H76_RS02745
uniprot id: A0A380KNF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

102684:I6H76 RS09660
gene id: 102684:I6H76_RS09660
uniprot id: A0A0U3ERW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

102684:I6H76 RS07300
gene id: 102684:I6H76_RS07300
uniprot id: A0A380KQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

102684:I6H76 RS09055
gene id: 102684:I6H76_RS09055
uniprot id: A0A380KR44
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS08180
gene id: 102684:I6H76_RS08180
uniprot id: A0A380KP34
names: Similarity
messages: Belongs to the leucine-binding protein family.

102684:I6H76 RS01325
gene id: 102684:I6H76_RS01325
uniprot id: A0A380KLY3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

102684:I6H76 RS00580
gene id: 102684:I6H76_RS00580
uniprot id: A0A380KMT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

102684:I6H76 RS06810
gene id: 102684:I6H76_RS06810
uniprot id: A0A380KR32
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

102684:I6H76 RS05400
gene id: 102684:I6H76_RS05400
uniprot id: A0A380KM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

102684:I6H76 RS00965
gene id: 102684:I6H76_RS00965
uniprot id: A0A380KM46
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

102684:I6H76 RS07140
gene id: 102684:I6H76_RS07140
uniprot id: A0A380KP14
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

102684:I6H76 RS01045
gene id: 102684:I6H76_RS01045
uniprot id: A0A380KNP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

102684:I6H76 RS05540
gene id: 102684:I6H76_RS05540
uniprot id: A0A380KK53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

102684:I6H76 RS05870
gene id: 102684:I6H76_RS05870
uniprot id: A0A380KRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

102684:I6H76 RS04070
gene id: 102684:I6H76_RS04070
uniprot id: A0A380KLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

102684:I6H76 RS03520
gene id: 102684:I6H76_RS03520
uniprot id: A0A380KKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

102684:I6H76 RS07465
gene id: 102684:I6H76_RS07465
uniprot id: A0A380KRC9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

102684:I6H76 RS03390
gene id: 102684:I6H76_RS03390
uniprot id: A0A380KND0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

102684:I6H76 RS01705
gene id: 102684:I6H76_RS01705
uniprot id: A0A380KLH7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.
messages: Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis.

102684:I6H76 RS00250
gene id: 102684:I6H76_RS00250
uniprot id: A0A380KMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

102684:I6H76 RS00155
gene id: 102684:I6H76_RS00155
uniprot id: A0A380KMF0
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

102684:I6H76 RS01615
gene id: 102684:I6H76_RS01615
uniprot id: A0A380KND6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

102684:I6H76 RS02910
gene id: 102684:I6H76_RS02910
uniprot id: A0A380KL22
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

102684:I6H76 RS02500
gene id: 102684:I6H76_RS02500
uniprot id: A0A380KNS8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09290
gene id: 102684:I6H76_RS09290
uniprot id: A0A380KN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

102684:I6H76 RS07455
gene id: 102684:I6H76_RS07455
uniprot id: A0A380KQR1
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

102684:I6H76 RS00335
gene id: 102684:I6H76_RS00335
uniprot id: A0A380KMH5
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS05810
gene id: 102684:I6H76_RS05810
uniprot id: A0A380KRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03865
gene id: 102684:I6H76_RS03865
uniprot id: A0A380KKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

102684:I6H76 RS09445
gene id: 102684:I6H76_RS09445
uniprot id: A0A380KN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

102684:I6H76 RS06885
gene id: 102684:I6H76_RS06885
uniprot id: A0A380KPC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08515
gene id: 102684:I6H76_RS08515
uniprot id: A0A380KRG2
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

102684:I6H76 RS09000
gene id: 102684:I6H76_RS09000
uniprot id: A0A380KR55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

102684:I6H76 RS05290
gene id: 102684:I6H76_RS05290
uniprot id: A0A0U3F629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

102684:I6H76 RS09335
gene id: 102684:I6H76_RS09335
uniprot id: A0A380KPM9
names: Similarity
messages: Belongs to the DNA photolyase family.

102684:I6H76 RS02275
gene id: 102684:I6H76_RS02275
uniprot id: A0A380KLJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

102684:I6H76 RS01345
gene id: 102684:I6H76_RS01345
uniprot id: A0A380KNI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

102684:I6H76 RS02635
gene id: 102684:I6H76_RS02635
uniprot id: A0A380KNU9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

102684:I6H76 RS00470
gene id: 102684:I6H76_RS00470
uniprot id: A0A380KQ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

102684:I6H76 RS00970
gene id: 102684:I6H76_RS00970
uniprot id: A0A380KNL1
names: Similarity
messages: Belongs to the DprA/Smf family.

102684:I6H76 RS03595
gene id: 102684:I6H76_RS03595
uniprot id: A0A380KKW2
names: Similarity
messages: Belongs to the peptidase C1 family.

102684:I6H76 RS01530
gene id: 102684:I6H76_RS01530
uniprot id: A0A380KLU0
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08190
gene id: 102684:I6H76_RS08190
uniprot id: A0A380KQC4
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08450
gene id: 102684:I6H76_RS08450
uniprot id: A0A380KQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

102684:I6H76 RS08165
gene id: 102684:I6H76_RS08165
uniprot id: A0A380KQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

102684:I6H76 RS01560
gene id: 102684:I6H76_RS01560
uniprot id: A0A380KPH6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS05975
gene id: 102684:I6H76_RS05975
uniprot id: A0A380KQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

102684:I6H76 RS07670
gene id: 102684:I6H76_RS07670
uniprot id: A0A0U3EYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

102684:I6H76 RS01745
gene id: 102684:I6H76_RS01745
uniprot id: A0A380KN62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

102684:I6H76 RS00720
gene id: 102684:I6H76_RS00720
uniprot id: A0A380KQ25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

102684:I6H76 RS03095
gene id: 102684:I6H76_RS03095
uniprot id: A0A380KMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

102684:I6H76 RS00795
gene id: 102684:I6H76_RS00795
uniprot id: A0A380KM84
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS07690
gene id: 102684:I6H76_RS07690
uniprot id: A0A380KRZ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

102684:I6H76 RS08160
gene id: 102684:I6H76_RS08160
uniprot id: A0A380KNX1
names: Similarity
messages: Belongs to the EamA transporter family.

102684:I6H76 RS03765
gene id: 102684:I6H76_RS03765
uniprot id: A0A380KKI7
names: Similarity
messages: Belongs to the LOG family.

102684:I6H76 RS09260
gene id: 102684:I6H76_RS09260
uniprot id: A0A380KQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

102684:I6H76 RS09190
gene id: 102684:I6H76_RS09190
uniprot id: A0A380KN35
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

102684:I6H76 RS07885
gene id: 102684:I6H76_RS07885
uniprot id: A0A0U2WBZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

102684:I6H76 RS00755
gene id: 102684:I6H76_RS00755
uniprot id: A0A380KM94
names: Similarity
messages: Belongs to the phosphohexose mutase family.

102684:I6H76 RS09475
gene id: 102684:I6H76_RS09475
uniprot id: A0A380KQ87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

102684:I6H76 RS06090
gene id: 102684:I6H76_RS06090
uniprot id: A0A380KRK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05865
gene id: 102684:I6H76_RS05865
uniprot id: A0A380KT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01725
gene id: 102684:I6H76_RS01725
uniprot id: A0A380KM75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

102684:I6H76 RS04935
gene id: 102684:I6H76_RS04935
uniprot id: A0A380KME4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

102684:I6H76 RS04890
gene id: 102684:I6H76_RS04890
uniprot id: A0A380KLE4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

102684:I6H76 RS07600
gene id: 102684:I6H76_RS07600
uniprot id: A0A380KPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

102684:I6H76 RS03795
gene id: 102684:I6H76_RS03795
uniprot id: A0A380KM12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

102684:I6H76 RS01450
gene id: 102684:I6H76_RS01450
uniprot id: A0A380KMC6
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS02720
gene id: 102684:I6H76_RS02720
uniprot id: A0A380KKX9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

102684:I6H76 RS06295
gene id: 102684:I6H76_RS06295
uniprot id: A0A380KRG8
names: Similarity
messages: Belongs to the CtsR family.

102684:I6H76 RS00445
gene id: 102684:I6H76_RS00445
uniprot id: A0A380KPQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

102684:I6H76 RS02860
gene id: 102684:I6H76_RS02860
uniprot id: A0A380KL31
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

102684:I6H76 RS02285
gene id: 102684:I6H76_RS02285
uniprot id: A0A380KN03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

102684:I6H76 RS09835
gene id: 102684:I6H76_RS09835
uniprot id: A0A380KPC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

102684:I6H76 RS04175
gene id: 102684:I6H76_RS04175
uniprot id: A0A380KKK0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08820
gene id: 102684:I6H76_RS08820
uniprot id: A0A380KNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

102684:I6H76 RS04910
gene id: 102684:I6H76_RS04910
uniprot id: A0A380KJV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS00680
gene id: 102684:I6H76_RS00680
uniprot id: A0A380KMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

102684:I6H76 RS07685
gene id: 102684:I6H76_RS07685
uniprot id: A0A380KPD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

102684:I6H76 RS02445
gene id: 102684:I6H76_RS02445
uniprot id: A0A380KNU0
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

102684:I6H76 RS06125
gene id: 102684:I6H76_RS06125
uniprot id: A0A380KQ63
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

102684:I6H76 RS09540
gene id: 102684:I6H76_RS09540
uniprot id: A0A380KPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

102684:I6H76 RS08725
gene id: 102684:I6H76_RS08725
uniprot id: A0A380KQN5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

102684:I6H76 RS07590
gene id: 102684:I6H76_RS07590
uniprot id: A0A380KS19
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09180
gene id: 102684:I6H76_RS09180
uniprot id: A0A380KN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

102684:I6H76 RS06300
gene id: 102684:I6H76_RS06300
uniprot id: A0A380KPN2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

102684:I6H76 RS02430
gene id: 102684:I6H76_RS02430
uniprot id: A0A380KMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

102684:I6H76 RS07125
gene id: 102684:I6H76_RS07125
uniprot id: A0A380KR00
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

102684:I6H76 RS07645
gene id: 102684:I6H76_RS07645
uniprot id: A0A380KQM2
names: Similarity
messages: Belongs to the asparaginase 1 family.

102684:I6H76 RS05020
gene id: 102684:I6H76_RS05020
uniprot id: A0A380KJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

102684:I6H76 RS00630
gene id: 102684:I6H76_RS00630
uniprot id: A0A380KMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

102684:I6H76 RS07975
gene id: 102684:I6H76_RS07975
uniprot id: A0A380KNL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

102684:I6H76 RS08575
gene id: 102684:I6H76_RS08575
uniprot id: A0A380KQR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

102684:I6H76 RS07940
gene id: 102684:I6H76_RS07940
uniprot id: A0A380KQH0
names: Similarity
messages: Belongs to the acylphosphatase family.

102684:I6H76 RS03140
gene id: 102684:I6H76_RS03140
uniprot id: A0A380KNJ7
names: Similarity
messages: Belongs to the Dps family.

102684:I6H76 RS02845
gene id: 102684:I6H76_RS02845
uniprot id: A0A380KNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS02590
gene id: 102684:I6H76_RS02590
uniprot id: A0A380KMU4
names: Similarity
messages: Belongs to the citrate synthase family.

102684:I6H76 RS03935
gene id: 102684:I6H76_RS03935
uniprot id: A0A380KKN8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

102684:I6H76 RS08300
gene id: 102684:I6H76_RS08300
uniprot id: A0A380KQX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

102684:I6H76 RS03500
gene id: 102684:I6H76_RS03500
uniprot id: A0A380KM79
names: Subcellular Location Annotation
messages: Cell membrane

102684:I6H76 RS07260
gene id: 102684:I6H76_RS07260
uniprot id: A0A380KRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

102684:I6H76 RS07610
gene id: 102684:I6H76_RS07610
uniprot id: A0A380KRL6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

102684:I6H76 RS03275
gene id: 102684:I6H76_RS03275
uniprot id: A0A380KKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

102684:I6H76 RS08425
gene id: 102684:I6H76_RS08425
uniprot id: A0A380KNX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS05355
gene id: 102684:I6H76_RS05355
uniprot id: A0A0U3EVN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS04030
gene id: 102684:I6H76_RS04030
uniprot id: A0A380KMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07285
gene id: 102684:I6H76_RS07285
uniprot id: A0A380KNY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

102684:I6H76 RS02265
gene id: 102684:I6H76_RS02265
uniprot id: A0A380KLD8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

102684:I6H76 RS07110
gene id: 102684:I6H76_RS07110
uniprot id: A0A380KRJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

102684:I6H76 RS01565
gene id: 102684:I6H76_RS01565
uniprot id: A0A380KNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

102684:I6H76 RS04720
gene id: 102684:I6H76_RS04720
uniprot id: A0A380KK31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS08795
gene id: 102684:I6H76_RS08795
uniprot id: A0A380KNB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

102684:I6H76 RS07365
gene id: 102684:I6H76_RS07365
uniprot id: A0A380KRE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS05905
gene id: 102684:I6H76_RS05905
uniprot id: A0A380KPR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

102684:I6H76 RS08850
gene id: 102684:I6H76_RS08850
uniprot id: A0A380KN41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09130
gene id: 102684:I6H76_RS09130
uniprot id: A0A380KN91
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

102684:I6H76 RS02310
gene id: 102684:I6H76_RS02310
uniprot id: A0A380KMU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

102684:I6H76 RS07620
gene id: 102684:I6H76_RS07620
uniprot id: A0A0U2TVZ5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

102684:I6H76 RS09570
gene id: 102684:I6H76_RS09570
uniprot id: A0A380KNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03155
gene id: 102684:I6H76_RS03155
uniprot id: A0A380KN82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

102684:I6H76 RS01750
gene id: 102684:I6H76_RS01750
uniprot id: A0A380KLP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

102684:I6H76 RS07115
gene id: 102684:I6H76_RS07115
uniprot id: A0A380KRW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

102684:I6H76 RS00710
gene id: 102684:I6H76_RS00710
uniprot id: A0A380KM30
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS03685
gene id: 102684:I6H76_RS03685
uniprot id: A0A380KKN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

102684:I6H76 RS09210
gene id: 102684:I6H76_RS09210
uniprot id: A0A380KPQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

102684:I6H76 RS00160
gene id: 102684:I6H76_RS00160
uniprot id: A0A380KMS9
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

102684:I6H76 RS09040
gene id: 102684:I6H76_RS09040
uniprot id: A0A380KN06
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04060
gene id: 102684:I6H76_RS04060
uniprot id: A0A380KKL9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

102684:I6H76 RS00460
gene id: 102684:I6H76_RS00460
uniprot id: A0A380KM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05955
gene id: 102684:I6H76_RS05955
uniprot id: A0A380KPR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

102684:I6H76 RS04160
gene id: 102684:I6H76_RS04160
uniprot id: A0A380KKE5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

102684:I6H76 RS04950
gene id: 102684:I6H76_RS04950
uniprot id: A0A380KMA8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

102684:I6H76 RS09890
gene id: 102684:I6H76_RS09890
uniprot id: A0A380KMS1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

102684:I6H76 RS06325
gene id: 102684:I6H76_RS06325
uniprot id: A0A380KQ24
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

102684:I6H76 RS05335
gene id: 102684:I6H76_RS05335
uniprot id: A0A380KM74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

102684:I6H76 RS04620
gene id: 102684:I6H76_RS04620
uniprot id: A0A380KK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS03480
gene id: 102684:I6H76_RS03480
uniprot id: A0A380KKS6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

102684:I6H76 RS02380
gene id: 102684:I6H76_RS02380
uniprot id: A0A380KMY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

102684:I6H76 RS02420
gene id: 102684:I6H76_RS02420
uniprot id: A0A380KLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

102684:I6H76 RS07915
gene id: 102684:I6H76_RS07915
uniprot id: A0A380KQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

102684:I6H76 RS09840
gene id: 102684:I6H76_RS09840
uniprot id: A0A380KMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

102684:I6H76 RS02670
gene id: 102684:I6H76_RS02670
uniprot id: A0A380KL65
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

102684:I6H76 RS00555
gene id: 102684:I6H76_RS00555
uniprot id: A0A380KMD5
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08210
gene id: 102684:I6H76_RS08210
uniprot id: A0A380KNV6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

102684:I6H76 RS05165
gene id: 102684:I6H76_RS05165
uniprot id: A0A380KJT3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

102684:I6H76 RS03105
gene id: 102684:I6H76_RS03105
uniprot id: A0A380KN92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

102684:I6H76 RS08255
gene id: 102684:I6H76_RS08255
uniprot id: A0A380KR75
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

102684:I6H76 RS07405
gene id: 102684:I6H76_RS07405
uniprot id: A0A380KQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

102684:I6H76 RS02920
gene id: 102684:I6H76_RS02920
uniprot id: A0A380KL73
names: Similarity
messages: Belongs to the TlyA family.

102684:I6H76 RS09100
gene id: 102684:I6H76_RS09100
uniprot id: A0A380KR33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

102684:I6H76 RS08260
gene id: 102684:I6H76_RS08260
uniprot id: A0A380KNU2
names: Similarity
messages: Belongs to the ArsC family.

102684:I6H76 RS09275
gene id: 102684:I6H76_RS09275
uniprot id: A0A654M9N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

102684:I6H76 RS08365
gene id: 102684:I6H76_RS08365
uniprot id: A0A380KQ95
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS02840
gene id: 102684:I6H76_RS02840
uniprot id: A0A380KND5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

102684:I6H76 RS02435
gene id: 102684:I6H76_RS02435
uniprot id: A0A380KLU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

102684:I6H76 RS03890
gene id: 102684:I6H76_RS03890
uniprot id: A0A380KN16
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

102684:I6H76 RS04575
gene id: 102684:I6H76_RS04575
uniprot id: A0A380KK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

102684:I6H76 RS02800
gene id: 102684:I6H76_RS02800
uniprot id: A0A380KNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

102684:I6H76 RS03650
gene id: 102684:I6H76_RS03650
uniprot id: A0A380KN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

102684:I6H76 RS01025
gene id: 102684:I6H76_RS01025
uniprot id: A0A380KLW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerS subfamily.
messages: Cytoplasm
messages: FtsK is required for recombination.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.

102684:I6H76 RS06080
gene id: 102684:I6H76_RS06080
uniprot id: A0A380KSH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS09485
gene id: 102684:I6H76_RS09485
uniprot id: A0A380KN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09120
gene id: 102684:I6H76_RS09120
uniprot id: A0A380KQF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

102684:I6H76 RS03010
gene id: 102684:I6H76_RS03010
uniprot id: A0A380KKX3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

102684:I6H76 RS03965
gene id: 102684:I6H76_RS03965
uniprot id: A0A380KKE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

102684:I6H76 RS07270
gene id: 102684:I6H76_RS07270
uniprot id: A0A380KPE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

102684:I6H76 RS03560
gene id: 102684:I6H76_RS03560
uniprot id: A0A380KN11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MapZ family.
messages: Cell membrane
messages: Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning.
messages: Interacts with FtsZ.

102684:I6H76 RS09870
gene id: 102684:I6H76_RS09870
uniprot id: A0A380KPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

102684:I6H76 RS06035
gene id: 102684:I6H76_RS06035
uniprot id: A0A380KQ26
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

102684:I6H76 RS09730
gene id: 102684:I6H76_RS09730
uniprot id: A0A380KMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

102684:I6H76 RS10010
gene id: 102684:I6H76_RS10010
uniprot id: A0A380KN85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09765
gene id: 102684:I6H76_RS09765
uniprot id: A0A380KN81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

102684:I6H76 RS06805
gene id: 102684:I6H76_RS06805
uniprot id: A0A0U3E359
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

102684:I6H76 RS06165
gene id: 102684:I6H76_RS06165
uniprot id: A0A0U2TWJ9
names: Similarity
messages: Belongs to the UPF0297 family.

102684:I6H76 RS09095
gene id: 102684:I6H76_RS09095
uniprot id: A0A380KNF3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS05795
gene id: 102684:I6H76_RS05795
uniprot id: A0A380KJD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

102684:I6H76 RS07805
gene id: 102684:I6H76_RS07805
uniprot id: A0A380KRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

102684:I6H76 RS01490
gene id: 102684:I6H76_RS01490
uniprot id: A0A380KPI8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS00300
gene id: 102684:I6H76_RS00300
uniprot id: A0A380KMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08445
gene id: 102684:I6H76_RS08445
uniprot id: A0A0U3FFC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

102684:I6H76 RS03635
gene id: 102684:I6H76_RS03635
uniprot id: A0A380KKP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

102684:I6H76 RS01440
gene id: 102684:I6H76_RS01440
uniprot id: A0A380KPJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

102684:I6H76 RS02730
gene id: 102684:I6H76_RS02730
uniprot id: A0A380KNS9
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS09685
gene id: 102684:I6H76_RS09685
uniprot id: A0A380KPF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08690
gene id: 102684:I6H76_RS08690
uniprot id: A0A380KQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

102684:I6H76 RS07155
gene id: 102684:I6H76_RS07155
uniprot id: A0A380KQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

102684:I6H76 RS03910
gene id: 102684:I6H76_RS03910
uniprot id: A0A380KN13
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03045
gene id: 102684:I6H76_RS03045
uniprot id: A0A380KML3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

102684:I6H76 RS02625
gene id: 102684:I6H76_RS02625
uniprot id: A0A380KKZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

102684:I6H76 RS04615
gene id: 102684:I6H76_RS04615
uniprot id: A0A380KLK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

102684:I6H76 RS06115
gene id: 102684:I6H76_RS06115
uniprot id: A0A380KSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

102684:I6H76 RS03920
gene id: 102684:I6H76_RS03920
uniprot id: A0A380KLZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09320
gene id: 102684:I6H76_RS09320
uniprot id: A0A380KQB6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

102684:I6H76 RS09930
gene id: 102684:I6H76_RS09930
uniprot id: A0A380KPZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

102684:I6H76 RS03330
gene id: 102684:I6H76_RS03330
uniprot id: A0A380KKU5
names: Similarity
messages: Belongs to the DCK/DGK family.

102684:I6H76 RS02600
gene id: 102684:I6H76_RS02600
uniprot id: A0A380KNI0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

102684:I6H76 RS05300
gene id: 102684:I6H76_RS05300
uniprot id: A0A0U2TRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

102684:I6H76 RS05460
gene id: 102684:I6H76_RS05460
uniprot id: A0A380KL46
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

102684:I6H76 RS07380
gene id: 102684:I6H76_RS07380
uniprot id: A0A380KQU9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

102684:I6H76 RS02465
gene id: 102684:I6H76_RS02465
uniprot id: A0A380KLA0
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS08235
gene id: 102684:I6H76_RS08235
uniprot id: A0A380KRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08110
gene id: 102684:I6H76_RS08110
uniprot id: A0A380KNY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

102684:I6H76 RS05305
gene id: 102684:I6H76_RS05305
uniprot id: A0A380KMC5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

102684:I6H76 RS01730
gene id: 102684:I6H76_RS01730
uniprot id: A0A380KNZ6
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07930
gene id: 102684:I6H76_RS07930
uniprot id: A0A380KP86
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

102684:I6H76 RS07565
gene id: 102684:I6H76_RS07565
uniprot id: A0A380KP81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

102684:I6H76 RS03660
gene id: 102684:I6H76_RS03660
uniprot id: A0A380KL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

102684:I6H76 RS07505
gene id: 102684:I6H76_RS07505
uniprot id: A0A0U3FFY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

102684:I6H76 RS00165
gene id: 102684:I6H76_RS00165
uniprot id: A0A380KQG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09735
gene id: 102684:I6H76_RS09735
uniprot id: A0A380KPE7
names: Similarity
messages: Belongs to the CapA family.

102684:I6H76 RS03695
gene id: 102684:I6H76_RS03695
uniprot id: A0A380KKT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

102684:I6H76 RS05930
gene id: 102684:I6H76_RS05930
uniprot id: A0A380KS52
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

102684:I6H76 RS00590
gene id: 102684:I6H76_RS00590
uniprot id: A0A0U3FPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

102684:I6H76 RS05520
gene id: 102684:I6H76_RS05520
uniprot id: A0A380KJF2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

102684:I6H76 RS07840
gene id: 102684:I6H76_RS07840
uniprot id: A0A380KQI8
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS02290
gene id: 102684:I6H76_RS02290
uniprot id: A0A0U2TTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS03625
gene id: 102684:I6H76_RS03625
uniprot id: A0A380KKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS09030
gene id: 102684:I6H76_RS09030
uniprot id: A0A380KPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

102684:I6H76 RS03775
gene id: 102684:I6H76_RS03775
uniprot id: A0A380KKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

102684:I6H76 RS03825
gene id: 102684:I6H76_RS03825
uniprot id: A0A380KKK1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

102684:I6H76 RS07145
gene id: 102684:I6H76_RS07145
uniprot id: A0A0U3DM00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

102684:I6H76 RS03855
gene id: 102684:I6H76_RS03855
uniprot id: A0A380KMV9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

102684:I6H76 RS08330
gene id: 102684:I6H76_RS08330
uniprot id: A0A380KNZ0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

102684:I6H76 RS06215
gene id: 102684:I6H76_RS06215
uniprot id: A0A380KSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08620
gene id: 102684:I6H76_RS08620
uniprot id: A0A380KNT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

102684:I6H76 RS03165
gene id: 102684:I6H76_RS03165
uniprot id: A0A380KKU8
names: Similarity
messages: Belongs to the TrpF family.

102684:I6H76 RS00940
gene id: 102684:I6H76_RS00940
uniprot id: A0A380KLY5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

102684:I6H76 RS07605
gene id: 102684:I6H76_RS07605
uniprot id: A0A380KRA1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

102684:I6H76 RS03255
gene id: 102684:I6H76_RS03255
uniprot id: A0A380KN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

102684:I6H76 RS01695
gene id: 102684:I6H76_RS01695
uniprot id: A0A380KN72
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

102684:I6H76 RS01005
gene id: 102684:I6H76_RS01005
uniprot id: A0A380KPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS08315
gene id: 102684:I6H76_RS08315
uniprot id: A0A380KQA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS04690
gene id: 102684:I6H76_RS04690
uniprot id: A0A380KLI3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

102684:I6H76 RS05960
gene id: 102684:I6H76_RS05960
uniprot id: A0A380KQD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

102684:I6H76 RS09135
gene id: 102684:I6H76_RS09135
uniprot id: A0A380KPS5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

102684:I6H76 RS04595
gene id: 102684:I6H76_RS04595
uniprot id: A0A380KLK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

102684:I6H76 RS00095
gene id: 102684:I6H76_RS00095
uniprot id: A0A380KP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS06435
gene id: 102684:I6H76_RS06435
uniprot id: A0A380KRW4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

102684:I6H76 RS02355
gene id: 102684:I6H76_RS02355
uniprot id: A0A380KMT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 2 subfamily.
messages: Heterodimer of AddA and RexB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity.

102684:I6H76 RS06415
gene id: 102684:I6H76_RS06415
uniprot id: A0A380KQ51
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

102684:I6H76 RS02570
gene id: 102684:I6H76_RS02570
uniprot id: A0A380KL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

102684:I6H76 RS01075
gene id: 102684:I6H76_RS01075
uniprot id: A0A380KM29
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

102684:I6H76 RS07540
gene id: 102684:I6H76_RS07540
uniprot id: A0A380KNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

102684:I6H76 RS06085
gene id: 102684:I6H76_RS06085
uniprot id: A0A380KQ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03395
gene id: 102684:I6H76_RS03395
uniprot id: A0A0U3FBF1
names: Similarity
messages: Belongs to the UPF0374 family.

102684:I6H76 RS00785
gene id: 102684:I6H76_RS00785
uniprot id: A0A380KPI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS07205
gene id: 102684:I6H76_RS07205
uniprot id: A0A380KQV1
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

102684:I6H76 RS03300
gene id: 102684:I6H76_RS03300
uniprot id: A0A380KMB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

102684:I6H76 RS08430
gene id: 102684:I6H76_RS08430
uniprot id: A0A380KQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

102684:I6H76 RS05310
gene id: 102684:I6H76_RS05310
uniprot id: A0A380KJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

102684:I6H76 RS03895
gene id: 102684:I6H76_RS03895
uniprot id: A0A380KLZ3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS07820
gene id: 102684:I6H76_RS07820
uniprot id: A0A380KNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

102684:I6H76 RS07370
gene id: 102684:I6H76_RS07370
uniprot id: A0A380KRR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

102684:I6H76 RS05800
gene id: 102684:I6H76_RS05800
uniprot id: A0A380KJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

102684:I6H76 RS01475
gene id: 102684:I6H76_RS01475
uniprot id: A0A380KLV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

102684:I6H76 RS04115
gene id: 102684:I6H76_RS04115
uniprot id: A0A380KKL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

102684:I6H76 RS09550
gene id: 102684:I6H76_RS09550
uniprot id: A0A380KMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

102684:I6H76 RS02305
gene id: 102684:I6H76_RS02305
uniprot id: A0A380KLB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

102684:I6H76 RS08245
gene id: 102684:I6H76_RS08245
uniprot id: A0A380KP21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

102684:I6H76 RS07550
gene id: 102684:I6H76_RS07550
uniprot id: A0A380KPE5
names: Similarity
messages: Belongs to the peptidase M24B family.

102684:I6H76 RS06160
gene id: 102684:I6H76_RS06160
uniprot id: A0A0U3ETL9
names: Similarity
messages: Belongs to the ArsC family.

102684:I6H76 RS03585
gene id: 102684:I6H76_RS03585
uniprot id: A0A380KKQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

102684:I6H76 RS04485
gene id: 102684:I6H76_RS04485
uniprot id: A0A380KKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

102684:I6H76 RS02685
gene id: 102684:I6H76_RS02685
uniprot id: A0A380KNT3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

102684:I6H76 RS09665
gene id: 102684:I6H76_RS09665
uniprot id: A0A380KPG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

102684:I6H76 RS01965
gene id: 102684:I6H76_RS01965
uniprot id: A0A380KM28
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

102684:I6H76 RS00265
gene id: 102684:I6H76_RS00265
uniprot id: A0A380KMZ9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

102684:I6H76 RS00635
gene id: 102684:I6H76_RS00635
uniprot id: A0A380KPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

102684:I6H76 RS03740
gene id: 102684:I6H76_RS03740
uniprot id: A0A380KN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

102684:I6H76 RS05375
gene id: 102684:I6H76_RS05375
uniprot id: A0A0U3EPC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS03575
gene id: 102684:I6H76_RS03575
uniprot id: A0A380KKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

102684:I6H76 RS01070
gene id: 102684:I6H76_RS01070
uniprot id: A0A380KNJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

102684:I6H76 RS08880
gene id: 102684:I6H76_RS08880
uniprot id: A0A380KQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

102684:I6H76 RS06200
gene id: 102684:I6H76_RS06200
uniprot id: A0A380KPQ1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

102684:I6H76 RS02405
gene id: 102684:I6H76_RS02405
uniprot id: A0A380KMS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

102684:I6H76 RS01445
gene id: 102684:I6H76_RS01445
uniprot id: A0A380KNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07680
gene id: 102684:I6H76_RS07680
uniprot id: A0A0U3FFV5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

102684:I6H76 RS09630
gene id: 102684:I6H76_RS09630
uniprot id: A0A380KQF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

102684:I6H76 RS08960
gene id: 102684:I6H76_RS08960
uniprot id: A0A380KNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

102684:I6H76 RS08230
gene id: 102684:I6H76_RS08230
uniprot id: A0A380KP16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

102684:I6H76 RS03945
gene id: 102684:I6H76_RS03945
uniprot id: A0A380KLX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

102684:I6H76 RS02795
gene id: 102684:I6H76_RS02795
uniprot id: A0A380KNE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

102684:I6H76 RS02335
gene id: 102684:I6H76_RS02335
uniprot id: A0A380KMZ5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

102684:I6H76 RS02575
gene id: 102684:I6H76_RS02575
uniprot id: A0A380KL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

102684:I6H76 RS01760
gene id: 102684:I6H76_RS01760
uniprot id: A0A380KLV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS01425
gene id: 102684:I6H76_RS01425
uniprot id: A0A380KLW1
names: Similarity
messages: Belongs to the UPF0758 family.

102684:I6H76 RS01320
gene id: 102684:I6H76_RS01320
uniprot id: A0A380KNE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

102684:I6H76 RS05405
gene id: 102684:I6H76_RS05405
uniprot id: A0A380KMA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS06095
gene id: 102684:I6H76_RS06095
uniprot id: A0A380KPR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01835
gene id: 102684:I6H76_RS01835
uniprot id: A0A380KP60
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS06860
gene id: 102684:I6H76_RS06860
uniprot id: A0A380KPR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

102684:I6H76 RS08065
gene id: 102684:I6H76_RS08065
uniprot id: A0A380KQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

102684:I6H76 RS04085
gene id: 102684:I6H76_RS04085
uniprot id: A0A380KMY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04815
gene id: 102684:I6H76_RS04815
uniprot id: A0A380KK09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

102684:I6H76 RS07305
gene id: 102684:I6H76_RS07305
uniprot id: A0A380KPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

102684:I6H76 RS05060
gene id: 102684:I6H76_RS05060
uniprot id: A0A380KLB5
names: Similarity
messages: Belongs to the UPF0177 family.

102684:I6H76 RS00170
gene id: 102684:I6H76_RS00170
uniprot id: A0A380KP67
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

102684:I6H76 RS01995
gene id: 102684:I6H76_RS01995
uniprot id: A0A380KLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

102684:I6H76 RS04970
gene id: 102684:I6H76_RS04970
uniprot id: A0A380KJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

102684:I6H76 RS01405
gene id: 102684:I6H76_RS01405
uniprot id: A0A380KP61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

102684:I6H76 RS02450
gene id: 102684:I6H76_RS02450
uniprot id: A0A380KL92
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

102684:I6H76 RS05080
gene id: 102684:I6H76_RS05080
uniprot id: A0A380KMB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

102684:I6H76 RS02830
gene id: 102684:I6H76_RS02830
uniprot id: A0A380KMQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

102684:I6H76 RS05395
gene id: 102684:I6H76_RS05395
uniprot id: A0A380KK82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

102684:I6H76 RS04905
gene id: 102684:I6H76_RS04905
uniprot id: A0A380KMI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08025
gene id: 102684:I6H76_RS08025
uniprot id: A0A380KNK3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04220
gene id: 102684:I6H76_RS04220
uniprot id: A0A380KK35
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

102684:I6H76 RS06470
gene id: 102684:I6H76_RS06470
uniprot id: A0A380KSQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07475
gene id: 102684:I6H76_RS07475
uniprot id: A0A380KP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01130
gene id: 102684:I6H76_RS01130
uniprot id: A0A380KLU1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 70 family.
messages: Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.

102684:I6H76 RS08370
gene id: 102684:I6H76_RS08370
uniprot id: A0A380KNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

102684:I6H76 RS07185
gene id: 102684:I6H76_RS07185
uniprot id: A0A380KP63
names: Similarity
messages: Belongs to the glutamate synthase family.

102684:I6H76 RS01260
gene id: 102684:I6H76_RS01260
uniprot id: A0A380KPG6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

102684:I6H76 RS05480
gene id: 102684:I6H76_RS05480
uniprot id: A0A380KM44
names: Similarity
messages: Belongs to the GARS family.

102684:I6H76 RS09745
gene id: 102684:I6H76_RS09745
uniprot id: A0A380KML8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

102684:I6H76 RS06475
gene id: 102684:I6H76_RS06475
uniprot id: A0A380KR90
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08770
gene id: 102684:I6H76_RS08770
uniprot id: A0A380KNQ8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

102684:I6H76 RS05360
gene id: 102684:I6H76_RS05360
uniprot id: A0A380KJN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

102684:I6H76 RS06385
gene id: 102684:I6H76_RS06385
uniprot id: A0A380KSA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

102684:I6H76 RS01145
gene id: 102684:I6H76_RS01145
uniprot id: A0A380KNM2
names: Similarity
messages: Belongs to the UPF0177 family.

102684:I6H76 RS04210
gene id: 102684:I6H76_RS04210
uniprot id: A0A380KLT7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09695
gene id: 102684:I6H76_RS09695
uniprot id: A0A380KMM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

102684:I6H76 RS04095
gene id: 102684:I6H76_RS04095
uniprot id: A0A380KLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS07200
gene id: 102684:I6H76_RS07200
uniprot id: A0A380KS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

102684:I6H76 RS08530
gene id: 102684:I6H76_RS08530
uniprot id: A0A380KQS4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS04045
gene id: 102684:I6H76_RS04045
uniprot id: A0A380KLW6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

102684:I6H76 RS04570
gene id: 102684:I6H76_RS04570
uniprot id: A0A380KLL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

102684:I6H76 RS07980
gene id: 102684:I6H76_RS07980
uniprot id: A0A380KP83
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

102684:I6H76 RS02300
gene id: 102684:I6H76_RS02300
uniprot id: A0A380KNX0
names: Similarity
messages: Belongs to the RecJ family.

102684:I6H76 RS00890
gene id: 102684:I6H76_RS00890
uniprot id: A0A380KM70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS08360
gene id: 102684:I6H76_RS08360
uniprot id: A0A380KNS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

102684:I6H76 RS07780
gene id: 102684:I6H76_RS07780
uniprot id: A0A380KPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

102684:I6H76 RS02915
gene id: 102684:I6H76_RS02915
uniprot id: A0A380KKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

102684:I6H76 RS08415
gene id: 102684:I6H76_RS08415
uniprot id: A0A380KNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

102684:I6H76 RS04965
gene id: 102684:I6H76_RS04965
uniprot id: A0A380KLD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

102684:I6H76 RS08250
gene id: 102684:I6H76_RS08250
uniprot id: A0A380KQY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS07965
gene id: 102684:I6H76_RS07965
uniprot id: A0A0U3DZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS00185
gene id: 102684:I6H76_RS00185
uniprot id: A0A380KML1
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS04020
gene id: 102684:I6H76_RS04020
uniprot id: A0A380KLW3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

102684:I6H76 RS04205
gene id: 102684:I6H76_RS04205
uniprot id: A0A380KKA5
names: Similarity
messages: Belongs to the ThiD family.

102684:I6H76 RS04260
gene id: 102684:I6H76_RS04260
uniprot id: A0A380KKC5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

102684:I6H76 RS00595
gene id: 102684:I6H76_RS00595
uniprot id: A0A380KMC9
names: Similarity
messages: Belongs to the UPF0223 family.

102684:I6H76 RS06170
gene id: 102684:I6H76_RS06170
uniprot id: A0A380KRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

102684:I6H76 RS00540
gene id: 102684:I6H76_RS00540
uniprot id: A0A380KPX2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

102684:I6H76 RS03555
gene id: 102684:I6H76_RS03555
uniprot id: A0A380KL85
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

102684:I6H76 RS04445
gene id: 102684:I6H76_RS04445
uniprot id: A0A380KLN9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

102684:I6H76 RS06305
gene id: 102684:I6H76_RS06305
uniprot id: A0A380KPK0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

102684:I6H76 RS06505
gene id: 102684:I6H76_RS06505
uniprot id: A0A380KPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS01250
gene id: 102684:I6H76_RS01250
uniprot id: A0A380KMF7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

102684:I6H76 RS02875
gene id: 102684:I6H76_RS02875
uniprot id: A0A380KNP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS09790
gene id: 102684:I6H76_RS09790
uniprot id: A0A380KMS3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

102684:I6H76 RS01470
gene id: 102684:I6H76_RS01470
uniprot id: A0A380KNA9
names: Similarity
messages: Belongs to the YjdM family.

102684:I6H76 RS00960
gene id: 102684:I6H76_RS00960
uniprot id: A0A380KPN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

102684:I6H76 RS00560
gene id: 102684:I6H76_RS00560
uniprot id: A0A380KM59
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

102684:I6H76 RS03160
gene id: 102684:I6H76_RS03160
uniprot id: A0A380KNG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

102684:I6H76 RS06270
gene id: 102684:I6H76_RS06270
uniprot id: A0A380KQ33
names: Similarity
messages: Belongs to the peptidase S66 family.

102684:I6H76 RS06855
gene id: 102684:I6H76_RS06855
uniprot id: A0A380KR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

102684:I6H76 RS04135
gene id: 102684:I6H76_RS04135
uniprot id: A0A380KMQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS03960
gene id: 102684:I6H76_RS03960
uniprot id: A0A380KN01
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

102684:I6H76 RS02695
gene id: 102684:I6H76_RS02695
uniprot id: A0A380KLP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS01420
gene id: 102684:I6H76_RS01420
uniprot id: A0A380KNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

102684:I6H76 RS07150
gene id: 102684:I6H76_RS07150
uniprot id: A0A380KSA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

102684:I6H76 RS05425
gene id: 102684:I6H76_RS05425
uniprot id: A0A380KJH2
names: Similarity
messages: Belongs to the threonine synthase family.

102684:I6H76 RS04920
gene id: 102684:I6H76_RS04920
uniprot id: A0A380KJY7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

102684:I6H76 RS04980
gene id: 102684:I6H76_RS04980
uniprot id: A0A380KK43
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS05345
gene id: 102684:I6H76_RS05345
uniprot id: A0A0U3DND1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

102684:I6H76 RS02865
gene id: 102684:I6H76_RS02865
uniprot id: A0A380KKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

102684:I6H76 RS03175
gene id: 102684:I6H76_RS03175
uniprot id: A0A380KKX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

102684:I6H76 RS06960
gene id: 102684:I6H76_RS06960
uniprot id: A0A380KPJ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

102684:I6H76 RS03600
gene id: 102684:I6H76_RS03600
uniprot id: A0A380KN88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

102684:I6H76 RS06330
gene id: 102684:I6H76_RS06330
uniprot id: A0A380KRX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

102684:I6H76 RS05465
gene id: 102684:I6H76_RS05465
uniprot id: A0A380KJP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

102684:I6H76 RS07275
gene id: 102684:I6H76_RS07275
uniprot id: A0A380KQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS04035
gene id: 102684:I6H76_RS04035
uniprot id: A0A380KMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

102684:I6H76 RS05380
gene id: 102684:I6H76_RS05380
uniprot id: A0A380KJZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

102684:I6H76 RS08080
gene id: 102684:I6H76_RS08080
uniprot id: A0A380KP59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

102684:I6H76 RS03540
gene id: 102684:I6H76_RS03540
uniprot id: A0A380KKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

102684:I6H76 RS09805
gene id: 102684:I6H76_RS09805
uniprot id: A0A380KQN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

102684:I6H76 RS03770
gene id: 102684:I6H76_RS03770
uniprot id: A0A380KM26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

102684:I6H76 RS08185
gene id: 102684:I6H76_RS08185
uniprot id: A0A380KRQ3
names: Subcellular Location Annotation
messages: Membrane

102684:I6H76 RS05490
gene id: 102684:I6H76_RS05490
uniprot id: A0A380KK63
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

102684:I6H76 RS01625
gene id: 102684:I6H76_RS01625
uniprot id: A0A380KP17
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

102684:I6H76 RS00655
gene id: 102684:I6H76_RS00655
uniprot id: A0A380KMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

102684:I6H76 RS00180
gene id: 102684:I6H76_RS00180
uniprot id: A0A380KQ52
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

102684:I6H76 RS07855
gene id: 102684:I6H76_RS07855
uniprot id: A0A380KRH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

102684:I6H76 RS05315
gene id: 102684:I6H76_RS05315
uniprot id: A0A380KL82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

102684:I6H76 RS01380
gene id: 102684:I6H76_RS01380
uniprot id: A0A380KLP1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

102684:I6H76 RS02890
gene id: 102684:I6H76_RS02890
uniprot id: A0A0U3DJI9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

102684:I6H76 RS00975
gene id: 102684:I6H76_RS00975
uniprot id: A0A380KM47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

102684:I6H76 RS05495
gene id: 102684:I6H76_RS05495
uniprot id: A0A380KM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

102684:I6H76 RS04865
gene id: 102684:I6H76_RS04865
uniprot id: A0A380KLE9
names: Subcellular Location Annotation
messages: Cell membrane

102684:I6H76 RS06955
gene id: 102684:I6H76_RS06955
uniprot id: A0A380KRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

102684:I6H76 RS00210
gene id: 102684:I6H76_RS00210
uniprot id: A0A380KQF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

102684:I6H76 RS06460
gene id: 102684:I6H76_RS06460
uniprot id: A0A380KPH0
names: Similarity
messages: Belongs to the LOR family.

102684:I6H76 RS05275
gene id: 102684:I6H76_RS05275
uniprot id: A0A0U3EVP9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

102684:I6H76 RS05340
gene id: 102684:I6H76_RS05340
uniprot id: A0A0U3FMN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

102684:I6H76 RS00520
gene id: 102684:I6H76_RS00520
uniprot id: A0A380KQ75
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

102684:I6H76 RS05730
gene id: 102684:I6H76_RS05730
uniprot id: A0A380KL26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

102684:I6H76 RS05135
gene id: 102684:I6H76_RS05135
uniprot id: A0A380KL89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.