Leptospira santarosai serovar Shermani str. LT 821 chromosome II, complete sequence.
Leptospira santarosai serovar Shermani str. LT 821
Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae; Leptospira.
Potential impact on kidney infection: a whole-genome analysis of Leptospira santarosai serovar Shermani
Emerg Microbes Infect 3 (11), e82 (2014)
Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes
Submitted (02-SEP-2013) Department of Medical Research and Development Linko Branch, Kidney Research Center, 5, Fu-Hsing Street. Kuei-Shan Hsiang, Tao-Yuan Hsien, Tao-Yuan, Taiwan, Taiwan
Submitted (07-APR-2011) Department of Medical Research and Development Linko Branch, Kidney Research Center, 5, Fu-Hsing Street. Kuei-Shan Hsiang, Tao-Yuan Hsien, Tao-Yuan, Taiwan, Taiwan
REFSEQ INFORMATION: The reference sequence is identical to\nCP006695.1.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Assembly-Data-START##\nAssembly Method :: CLC v. 5.5, HGAP, AHA from\n smrtanalysis-2.0.1, Velvet v.1.2.03\nGenome Coverage :: 751.07X\nSequencing Technology :: Illumina paired-end and mate-paired: Roche\n 454 GS FLX Titanium: PacBio RS 3rd\n Generation SMRT Sequencing\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 03/12/2023 18:00:29\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.4\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 3,611\nCDSs (total) :: 3,567\nGenes (coding) :: 3,468\nCDSs (with protein) :: 3,468\nGenes (RNA) :: 44\nrRNAs :: 1, 2, 2 (5S, 16S, 23S)\ncomplete rRNAs :: 1, 2, 2 (5S, 16S, 23S)\ntRNAs :: 37\nncRNAs :: 2\nPseudo Genes (total) :: 99\nCDSs (without protein) :: 99\nPseudo Genes (ambiguous residues) :: 0 of 99\nPseudo Genes (frameshifted) :: 56 of 99\nPseudo Genes (incomplete) :: 62 of 99\nPseudo Genes (internal stop) :: 21 of 99\nPseudo Genes (multiple problems) :: 33 of 99\nCRISPR Arrays :: 4\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
COORDINATES: similar to AA sequence:RefSeq:WP_000931507.1
GO:0043565 - sequence-specific DNA binding [Evidence IEA]
Derived by automated computational analysis using gene prediction method: Protein Homology.
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_000637633.1
COORDINATES: similar to AA sequence:RefSeq:WP_004490191.1
GO:0007059 - chromosome segregation [Evidence IEA]; GO:0000910 - cytokinesis [Evidence IEA]
ParB/RepB/Spo0J family partition protein
COORDINATES: similar to AA sequence:RefSeq:WP_004484359.1
COORDINATES: similar to AA sequence:RefSeq:WP_004756381.1
COORDINATES: similar to AA sequence:RefSeq:WP_011671237.1
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]
GO:0009086 - methionine biosynthetic process [Evidence IEA]
methylenetetrahydrofolate reductase [NAD(P)H]
COORDINATES: similar to AA sequence:RefSeq:WP_010679666.1
COORDINATES: similar to AA sequence:RefSeq:WP_000007034.1
GO:0016787 - hydrolase activity [Evidence IEA]
GO:0008152 - metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000550726.1
COORDINATES: similar to AA sequence:RefSeq:WP_000269775.1
COORDINATES: similar to AA sequence:RefSeq:WP_002764052.1
bifunctional porphobilinogen deaminase/uroporphyrinogen synthase
COORDINATES: similar to AA sequence:RefSeq:WP_017850118.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0004655 - porphobilinogen synthase activity [Evidence IEA]
GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004487548.1
glutamate-1-semialdehyde 2,1-aminomutase
COORDINATES: similar to AA sequence:RefSeq:WP_004459923.1
HAMP domain-containing sensor histidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_001201859.1
COORDINATES: similar to AA sequence:RefSeq:WP_020779373.1
GO:0004853 - uroporphyrinogen decarboxylase activity [Evidence IEA]
GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]
uroporphyrinogen decarboxylase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_017858300.1
GO:0051989 - coproporphyrinogen dehydrogenase activity [Evidence IEA]
oxygen-independent coproporphyrinogen III oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_004477014.1
COORDINATES: similar to AA sequence:RefSeq:WP_004481036.1
GO:0004729 - oxygen-dependent protoporphyrinogen oxidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010572210.1
GO:0004325 - ferrochelatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002162152.1
COORDINATES: similar to AA sequence:RefSeq:WP_001086265.1
COORDINATES: similar to AA sequence:RefSeq:WP_002556565.1
COORDINATES: similar to AA sequence:RefSeq:WP_000684128.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459907.1
COORDINATES: similar to AA sequence:RefSeq:WP_016756739.1
COORDINATES: similar to AA sequence:RefSeq:WP_004464833.1
cyclic nucleotide-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_016751885.1
COORDINATES: similar to AA sequence:RefSeq:WP_002728954.1
low molecular weight protein-tyrosine-phosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_000504735.1
COORDINATES: similar to AA sequence:RefSeq:WP_004464894.1
COORDINATES: similar to AA sequence:RefSeq:WP_004485448.1
COORDINATES: similar to AA sequence:RefSeq:WP_011669463.1
COORDINATES: similar to AA sequence:RefSeq:WP_011669462.1
COORDINATES: similar to AA sequence:RefSeq:WP_004470420.1
COORDINATES: similar to AA sequence:RefSeq:WP_016756820.1
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004459893.1
COORDINATES: similar to AA sequence:RefSeq:WP_000701961.1
frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004464816.1
COORDINATES: similar to AA sequence:RefSeq:WP_004494551.1
SDR family NAD(P)-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_000450145.1
COORDINATES: similar to AA sequence:RefSeq:WP_004767885.1
COORDINATES: similar to AA sequence:RefSeq:WP_020766416.1
COORDINATES: similar to AA sequence:RefSeq:WP_002625190.1
COORDINATES: similar to AA sequence:RefSeq:WP_002150854.1
COORDINATES: similar to AA sequence:RefSeq:WP_004492961.1
COORDINATES: similar to AA sequence:RefSeq:WP_017850791.1
COORDINATES: similar to AA sequence:RefSeq:WP_008393660.1
COORDINATES: similar to AA sequence:RefSeq:WP_004757688.1
COORDINATES: similar to AA sequence:RefSeq:WP_001011135.1
COORDINATES: similar to AA sequence:RefSeq:WP_016754337.1
COORDINATES: similar to AA sequence:RefSeq:WP_000809741.1
COORDINATES: similar to AA sequence:RefSeq:WP_004490179.1
COORDINATES: similar to AA sequence:RefSeq:WP_001287996.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017861739.1
COORDINATES: similar to AA sequence:RefSeq:WP_004472073.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459871.1
COORDINATES: similar to AA sequence:RefSeq:WP_004483963.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459867.1
COORDINATES: similar to AA sequence:RefSeq:WP_004493754.1
GO:0004803 - transposase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004476811.1
COORDINATES: similar to AA sequence:RefSeq:WP_008393650.1
COORDINATES: similar to AA sequence:RefSeq:WP_016552073.1
COORDINATES: similar to AA sequence:RefSeq:WP_000676636.1
NAD(P)-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004481813.1
COORDINATES: similar to AA sequence:RefSeq:WP_020765752.1
GO:0031004 - potassium ion-transporting ATPase complex [Evidence IEA]
GO:0008556 - P-type potassium transmembrane transporter activity [Evidence IEA]
GO:0006813 - potassium ion transport [Evidence IEA]
potassium-transporting ATPase subunit KdpA
COORDINATES: similar to AA sequence:RefSeq:WP_004473375.1
potassium-transporting ATPase subunit KdpB
COORDINATES: similar to AA sequence:RefSeq:WP_016754728.1
potassium-transporting ATPase subunit KdpC
COORDINATES: similar to AA sequence:RefSeq:WP_004462734.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462733.1
COORDINATES: similar to AA sequence:RefSeq:WP_000877316.1
protein kinase involved in LAO amino acid transport and metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_010572250.1
GO:0016866 - intramolecular transferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000362808.1
COORDINATES: similar to AA sequence:RefSeq:WP_004487559.1
COORDINATES: similar to AA sequence:RefSeq:WP_000445690.1
COORDINATES: similar to AA sequence:RefSeq:WP_016552072.1
COORDINATES: similar to AA sequence:RefSeq:WP_004479491.1
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_004481614.1
COORDINATES: similar to AA sequence:RefSeq:WP_004463291.1
COORDINATES: similar to AA sequence:RefSeq:WP_004463293.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611485.1
COORDINATES: similar to AA sequence:RefSeq:WP_011345585.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004803 - transposase activity [Evidence IEA]
GO:0006313 - transposition, DNA-mediated [Evidence IEA]
incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004481427.1
COORDINATES: protein motif:HMM:NF024977.2
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004764489.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400550.1
COORDINATES: similar to AA sequence:RefSeq:WP_002749410.1
GO:0009975 - cyclase activity [Evidence IEA]
GO:0009966 - regulation of signal transduction [Evidence IEA]
sensor domain-containing diguanylate cyclase
COORDINATES: similar to AA sequence:RefSeq:WP_002749331.1
COORDINATES: similar to AA sequence:RefSeq:WP_004444096.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462382.1
TetR/AcrR family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_004481606.1
COORDINATES: similar to AA sequence:RefSeq:WP_017213508.1
COORDINATES: similar to AA sequence:RefSeq:WP_004478830.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462392.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462394.1
COORDINATES: similar to AA sequence:RefSeq:WP_000388447.1
COORDINATES: similar to AA sequence:RefSeq:WP_002732191.1
COORDINATES: similar to AA sequence:RefSeq:WP_000747968.1
COORDINATES: similar to AA sequence:RefSeq:WP_010576319.1
GO:0016791 - phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010576312.1
COORDINATES: similar to AA sequence:RefSeq:WP_002630119.1
patatin-like phospholipase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_016756576.1
COORDINATES: similar to AA sequence:RefSeq:WP_000503524.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462411.1
COORDINATES: similar to AA sequence:RefSeq:WP_004489248.1
GO:0009190 - cyclic nucleotide biosynthetic process [Evidence IEA]; GO:0035556 - intracellular signal transduction [Evidence IEA]
adenylate/guanylate cyclase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004468717.1
polysaccharide deacetylase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004459707.1
COORDINATES: similar to AA sequence:RefSeq:WP_000409183.1
COORDINATES: similar to AA sequence:RefSeq:WP_004492452.1
COORDINATES: similar to AA sequence:RefSeq:WP_016754072.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
metalloregulator ArsR/SmtB family transcription factor
COORDINATES: similar to AA sequence:RefSeq:WP_017855632.1
GO:0004013 - adenosylhomocysteinase activity [Evidence IEA]
GO:0006730 - one-carbon metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004496665.1
COORDINATES: similar to AA sequence:RefSeq:WP_002191754.1
GO:0008705 - methionine synthase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004478784.1
COORDINATES: similar to AA sequence:RefSeq:WP_016750706.1
COORDINATES: similar to AA sequence:RefSeq:WP_020766257.1
COORDINATES: similar to AA sequence:RefSeq:WP_016752995.1
COORDINATES: similar to AA sequence:RefSeq:WP_004756398.1
GO:0003991 - acetylglutamate kinase activity [Evidence IEA]
GO:0006592 - ornithine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016757871.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459693.1
COORDINATES: similar to AA sequence:RefSeq:WP_020772474.1
COORDINATES: similar to AA sequence:RefSeq:WP_000626856.1
COORDINATES: similar to AA sequence:RefSeq:WP_004475382.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459686.1
COORDINATES: similar to AA sequence:RefSeq:WP_002722257.1
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017857701.1
COORDINATES: similar to AA sequence:RefSeq:WP_000659897.1
COORDINATES: similar to AA sequence:RefSeq:WP_000956229.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400558.1
COORDINATES: similar to AA sequence:RefSeq:WP_004478706.1
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004492256.1
COORDINATES: similar to AA sequence:RefSeq:WP_002179870.1
COORDINATES: similar to AA sequence:RefSeq:WP_000377734.1
UTP--glucose-1-phosphate uridylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_002739639.1
COORDINATES: similar to AA sequence:RefSeq:WP_001221437.1
GO:0008234 - cysteine-type peptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004428370.1
COORDINATES: similar to AA sequence:RefSeq:WP_010572405.1
COORDINATES: similar to AA sequence:RefSeq:WP_003010252.1
COORDINATES: similar to AA sequence:RefSeq:WP_000177702.1
MotA/TolQ/ExbB proton channel family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004468691.1
COORDINATES: similar to AA sequence:RefSeq:WP_002732199.1
TonB-dependent receptor plug domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_002760072.1
COORDINATES: similar to AA sequence:RefSeq:WP_004473164.1
COORDINATES: similar to AA sequence:RefSeq:WP_017852115.1
COORDINATES: similar to AA sequence:RefSeq:WP_004492323.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
methylmalonyl Co-A mutase-associated GTPase MeaB
COORDINATES: similar to AA sequence:RefSeq:WP_000828542.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0004494 - methylmalonyl-CoA mutase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020783999.1
COORDINATES: similar to AA sequence:RefSeq:WP_002749559.1
COORDINATES: similar to AA sequence:RefSeq:WP_004764476.1
COORDINATES: similar to AA sequence:RefSeq:WP_004478808.1
COORDINATES: similar to AA sequence:RefSeq:WP_004471400.1
aminotransferase class V-fold PLP-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_002998741.1
bile acid:sodium symporter family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004459639.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000315 - organellar large ribosomal subunit [Evidence IEA]
GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020767727.1
TraR/DksA family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_004492250.1
COORDINATES: similar to AA sequence:RefSeq:WP_000928205.1
GO:0070007 - glutamic-type endopeptidase activity [Evidence IEA]
PrsW family glutamic-type intramembrane protease
COORDINATES: similar to AA sequence:RefSeq:WP_004459632.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400377.1
GO:0008168 - methyltransferase activity [Evidence IEA]
GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]
ubiquinone/menaquinone biosynthesis methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004436270.1
COORDINATES: similar to AA sequence:RefSeq:WP_017852352.1
COORDINATES: similar to AA sequence:RefSeq:WP_004475397.1
COORDINATES: similar to AA sequence:RefSeq:WP_004473176.1
COORDINATES: similar to AA sequence:RefSeq:WP_000578215.1
COORDINATES: similar to AA sequence:RefSeq:WP_000666143.1
COORDINATES: similar to AA sequence:RefSeq:WP_002179700.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400595.1
COORDINATES: similar to AA sequence:RefSeq:WP_004489280.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459616.1
COORDINATES: similar to AA sequence:RefSeq:WP_020783989.1
COORDINATES: similar to AA sequence:RefSeq:WP_004471414.1
GO:0016853 - isomerase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA
COORDINATES: similar to AA sequence:RefSeq:WP_020772498.1
COORDINATES: similar to AA sequence:RefSeq:WP_004780750.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459609.1
YbaB/EbfC family nucleoid-associated protein
COORDINATES: similar to AA sequence:RefSeq:WP_008400368.1
COORDINATES: similar to AA sequence:RefSeq:WP_017863044.1
leucine-rich repeat domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_001226840.1
COORDINATES: similar to AA sequence:RefSeq:WP_004467608.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400547.1
COORDINATES: similar to AA sequence:RefSeq:WP_004489854.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020784922.1
COORDINATES: similar to AA sequence:RefSeq:WP_017853731.1
COORDINATES: similar to AA sequence:RefSeq:WP_004468934.1
dolichyl-phosphate-mannose--protein mannosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004471408.1
COORDINATES: similar to AA sequence:RefSeq:WP_004750207.1
COORDINATES: similar to AA sequence:RefSeq:WP_004425963.1
GO:0003999 - adenine phosphoribosyltransferase activity [Evidence IEA]
GO:0006168 - adenine salvage [Evidence IEA]; GO:0009116 - nucleoside metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017852795.1
GO:0004222 - metalloendopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016560280.1
COORDINATES: similar to AA sequence:RefSeq:WP_004762706.1
ClpXP protease specificity-enhancing factor SspB
COORDINATES: similar to AA sequence:RefSeq:WP_004766563.1
nucleoside-diphosphate sugar epimerase/dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_004459592.1
COORDINATES: similar to AA sequence:RefSeq:WP_004454620.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00174
cobalamin riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_016755784.1
GO:0016829 - lyase activity [Evidence IEA]
CbiX/SirB N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004430641.1
COORDINATES: similar to AA sequence:RefSeq:WP_004482085.1
GO:0009236 - cobalamin biosynthetic process [Evidence IEA]
cobalt-precorrin-5B (C(1))-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_000999239.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400362.1
bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020772496.1
GO:0030788 - precorrin-2 C20-methyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004477234.1
COORDINATES: similar to AA sequence:RefSeq:WP_016755787.1
GO:0030789 - precorrin-3B C17-methyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000870279.1
GO:0046026 - precorrin-4 C11-methyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_001083454.1
GO:0008817 - corrinoid adenosyltransferase activity [Evidence IEA]
cob(I)yrinic acid a,c-diamide adenosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004482071.1
GO:0042242 - cobyrinic acid a,c-diamide synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004482097.1
COORDINATES: similar to AA sequence:RefSeq:WP_016754308.1
GO:0043752 - adenosylcobinamide kinase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004467705.1
GO:0003824 - catalytic activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004470814.1
GO:0016880 - acid-ammonia (or amide) ligase activity [Evidence IEA]
adenosylcobinamide-phosphate synthase CbiB
COORDINATES: similar to AA sequence:RefSeq:WP_004494081.1
COORDINATES: similar to AA sequence:RefSeq:WP_017863380.1
GO:0003964 - RNA-directed DNA polymerase activity [Evidence IEA]
GO:0000373 - Group II intron splicing [Evidence IEA]
group II intron reverse transcriptase/maturase
COORDINATES: similar to AA sequence:RefSeq:WP_001130056.1
COORDINATES: similar to AA sequence:RefSeq:WP_016755794.1
COORDINATES: similar to AA sequence:RefSeq:WP_004508466.1
COORDINATES: similar to AA sequence:RefSeq:WP_000866535.1
COORDINATES: similar to AA sequence:RefSeq:WP_004488995.1
COORDINATES: similar to AA sequence:RefSeq:WP_004488820.1
COORDINATES: similar to AA sequence:RefSeq:WP_016551606.1
COORDINATES: similar to AA sequence:RefSeq:WP_004473146.1
COORDINATES: similar to AA sequence:RefSeq:WP_004483471.1
COORDINATES: similar to AA sequence:RefSeq:WP_004492674.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462829.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462828.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462826.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462824.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003916 - DNA topoisomerase activity [Evidence IEA]
GO:0006270 - DNA replication initiation [Evidence IEA]
replication initiation factor domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004488621.1
COORDINATES: similar to AA sequence:RefSeq:WP_004449840.1
COORDINATES: similar to AA sequence:RefSeq:WP_004488622.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462819.1
COORDINATES: similar to AA sequence:RefSeq:WP_001185452.1
COORDINATES: similar to AA sequence:RefSeq:WP_000885247.1
COORDINATES: similar to AA sequence:RefSeq:WP_004491140.1
COORDINATES: similar to AA sequence:RefSeq:WP_004483458.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462813.1
COORDINATES: similar to AA sequence:RefSeq:WP_016551621.1
COORDINATES: similar to AA sequence:RefSeq:WP_004483481.1
D-Ala-D-Ala carboxypeptidase family metallohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_004488832.1
COORDINATES: similar to AA sequence:RefSeq:WP_004477148.1
COORDINATES: similar to AA sequence:RefSeq:WP_004487494.1
COORDINATES: similar to AA sequence:RefSeq:WP_004483461.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462803.1
COORDINATES: similar to AA sequence:RefSeq:WP_004462801.1
GO:0008233 - peptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016551605.1
COORDINATES: similar to AA sequence:RefSeq:WP_000425065.1
COORDINATES: similar to AA sequence:RefSeq:WP_016754305.1
COORDINATES: similar to AA sequence:RefSeq:WP_020198553.1
COORDINATES: similar to AA sequence:RefSeq:WP_000392371.1
COORDINATES: similar to AA sequence:RefSeq:WP_020780697.1
sigma-70 family RNA polymerase sigma factor
COORDINATES: similar to AA sequence:RefSeq:WP_004481081.1
COORDINATES: similar to AA sequence:RefSeq:WP_004426094.1
COORDINATES: similar to AA sequence:RefSeq:WP_000391762.1
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]
GO:0071704 - organic substance metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004460052.1
COORDINATES: similar to AA sequence:RefSeq:WP_000094629.1
COORDINATES: similar to AA sequence:RefSeq:WP_004488600.1
acetyl-CoA hydrolase/transferase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_017852108.1
COORDINATES: similar to AA sequence:RefSeq:WP_002733357.1
FMN-binding glutamate synthase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004460042.1
COORDINATES: similar to AA sequence:RefSeq:WP_020784008.1
COORDINATES: similar to AA sequence:RefSeq:WP_002749394.1
COORDINATES: similar to AA sequence:RefSeq:WP_004428390.1
COORDINATES: similar to AA sequence:RefSeq:WP_011671396.1
GO:0016835 - carbon-oxygen lyase activity [Evidence IEA]
GO:0019509 - L-methionine salvage from methylthioadenosine [Evidence IEA]
methylthioribulose 1-phosphate dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_000201440.1
COORDINATES: similar to AA sequence:RefSeq:WP_002733336.1
GO:0003746 - translation elongation factor activity [Evidence IEA]
GO:0006414 - translational elongation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000768211.1
phosphate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_004468976.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0016853 - isomerase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017862878.1
COORDINATES: similar to AA sequence:RefSeq:WP_020762606.1
COORDINATES: similar to AA sequence:RefSeq:WP_004478782.1
COORDINATES: similar to AA sequence:RefSeq:WP_004490401.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400661.1
GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]
GO:0009220 - pyrimidine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017809925.1
COORDINATES: similar to AA sequence:RefSeq:WP_002733373.1
GO:0004014 - adenosylmethionine decarboxylase activity [Evidence IEA]
GO:0008295 - spermidine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000992621.1
COORDINATES: similar to AA sequence:RefSeq:WP_004429706.1
COORDINATES: similar to AA sequence:RefSeq:WP_002179820.1
COORDINATES: similar to AA sequence:RefSeq:WP_004478800.1
COORDINATES: similar to AA sequence:RefSeq:WP_004464839.1
COORDINATES: similar to AA sequence:RefSeq:WP_004464908.1
COORDINATES: similar to AA sequence:RefSeq:WP_020784439.1
GO:0008784 - alanine racemase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_001157559.1
1-acyl-sn-glycerol-3-phosphate acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004494230.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459993.1
COORDINATES: similar to AA sequence:RefSeq:WP_004464824.1
COORDINATES: similar to AA sequence:RefSeq:WP_004477013.1
COORDINATES: similar to AA sequence:RefSeq:WP_010579388.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459983.1
lytic transglycosylase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_002760189.1
COORDINATES: similar to AA sequence:RefSeq:WP_016753995.1
GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002190828.1
GO:0003994 - aconitate hydratase activity [Evidence IEA]
GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004485674.1
COORDINATES: similar to AA sequence:RefSeq:WP_002760137.1
elongation factor P--(R)-beta-lysine ligase
COORDINATES: similar to AA sequence:RefSeq:WP_020772381.1
COORDINATES: similar to AA sequence:RefSeq:WP_017213442.1
COORDINATES: similar to AA sequence:RefSeq:WP_004757601.1
COORDINATES: similar to AA sequence:RefSeq:WP_008400559.1
4a-hydroxytetrahydrobiopterin dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_010579398.1
COORDINATES: similar to AA sequence:RefSeq:WP_002179703.1
COORDINATES: similar to AA sequence:RefSeq:WP_002622601.1
COORDINATES: similar to AA sequence:RefSeq:WP_004490203.1
COORDINATES: similar to AA sequence:RefSeq:WP_004456332.1
GO:0004743 - pyruvate kinase activity [Evidence IEA]
GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000892875.1
COORDINATES: similar to AA sequence:RefSeq:WP_000092012.1
GO:0004073 - aspartate-semialdehyde dehydrogenase activity [Evidence IEA]
GO:0009089 - lysine biosynthetic process via diaminopimelate [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016552083.1
COORDINATES: similar to AA sequence:RefSeq:WP_017862886.1
COORDINATES: similar to AA sequence:RefSeq:WP_020766068.1
COORDINATES: similar to AA sequence:RefSeq:WP_010572574.1
COORDINATES: similar to AA sequence:RefSeq:WP_002749505.1
COORDINATES: similar to AA sequence:RefSeq:WP_004459942.1
COORDINATES: similar to AA sequence:RefSeq:WP_020763258.1