Komagataella phaffii GS115 chromosome 4, complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella.
Genome sequence of the recombinant protein production host Pichia pastoris
Submitted (17-FEB-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (05-MAY-2009) Callewaert N., Department for Molecular Biomedical Research, Flanders Institute for Biotechnology (VIB) / Gent University, Technologiepark 927, Ghent, 9052, BELGIUM
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to FN392322.\nContact: Nico Callewaert\nUnit for Molecular Glycobiology\nLaboratory for Protein Biochemistry and Biomolecular Engineering\nDepartment of Biochemistry, Physiology and Microbiology, UGent VIB\nDepartment for Molecular Biomedical Research, UGent Technologiepark\n927, B-9052 Gent, Belgium\nTel: (32)93313630\nFax: (32)93313609\nEmail: nico.callewaert@dmbr.vib-UGent.be\n----------- sequencing/assembly\nUnit for Molecular Glycobiology\nLaboratory for Protein Biochemistry and Biomolecular Engineering\nDepartment of Biochemistry, Physiology and Microbiology, UGent VIB\nDepartment for Molecular Biomedical Research, UGent -----------\nannotation\nUnit for Molecular Glycobiology\nLaboratory for Protein Biochemistry and Biomolecular Engineering\nDepartment of Biochemistry, Physiology and Microbiology, UGent VIB\nDepartment for Molecular Biomedical Research, UGent\n\nLaboratory for Bioinformatics and Evolutionary Genomics VIB\nDepartment of Plant Systems Biology, UGent\nWeb site: http://bioinformatics.psb.ugent.be/\nBioinformatics Online Genome Annotation System (BOGAS):\nhttp://bioinformatics.psb.ugent.be/webtools/bogas/ -----------\n* NOTE: finishing of chromosomes in process\n* Final curation of the annotation in progress.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
Proton-coupled oligopeptide transporter of the plasma membrane
High affinity nicotinic acid plasma membrane permease
Low-affinity Fe(II) transporter of the plasma membrane
Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter)
Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
Component of the spliceosome complex involved in pre-mRNA splicing
Guanosine diphosphatase located in the Golgi
Ubiquitin-specific protease that may play a role in ubiquitin precursor processing
Putative pantetheine-phosphate adenylyltransferase (PPAT)
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)
Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
Alpha subunit of the translation initiation factor eIF2B
Mitochondrial elongation factor involved in translational elongation
Subunit of heterotrimeric Replication Protein A (RPA)
Protein kinase involved in the response to oxidative and osmotic stress
Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes
Meiosis-specific protein with similarity to phospholipase B
Mitochondrial outer membrane and cell wall localized SUN family member
Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles
Intracellular beta-1,3-endoglucanase, expression is induced during sporulation
Mitochondrial protein, putative inner membrane transporter
Chorismate mutase, catalyzes the conversion of chorismate to prephenate
putative Hsp40p co-chaperone, has a DnaJ-like domain
Evolutionarily conserved glucosamine-6-phosphate acetyltransferase
Component of the RNA polymerase II general transcription and DNA repair factor TFIIH
C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis
Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP)
Alpha 1 subunit of the 20S core complex of the 26S proteasome
Mitochondrial ribosomal protein of the small subunit
Nucleosome assembly factor, involved in chromatin assembly and disassembly
Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide
Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p)
One of two (see also PSK1) PAS domain containing S/T protein kinases
Essential protein with dual roles in spliceosome assembly and exocytosis
Essential protein involved in a late step of 60S ribosomal subunit assembly or modification
Splicing factor that is found in the Cef1p subcomplex of the spliceosome
Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4)
Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase
Putative acyltransferase with similarity to Eeb1p and Eht1p
Protein involved in the repair of double-strand breaks in DNA during vegetative growth
Essential protein involved in intracellular protein transport
Trimethyl guanosine synthase, conserved nucleolar methyl transferase
Kinesin-related motor protein involved in mitotic spindle positioning
Putative transcription factor involved in regulating the response to osmotic stress
Subunit of the SF3a splicing factor complex, required for spliceosome assembly
Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA
Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex
Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA
elongation factor 1 gamma domain-containing protein
Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p
Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus
Component of the condensin complex, essential SMC chromosomal ATPase family member
Low affinity methionine permease, similar to Mup1p
Protein involved in cell morphogenesis and proliferation, associated with protein kinase Cbk1p
Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p
putative transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family
ATP-binding protein required for mismatch repair in mitosis and meiosis
Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes
Subunit of the histone deacetylase Rpd3L complex
Small subunit of carbamoyl phosphate synthetase
ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase
RNA binding protein, component of the U1 snRNP protein
Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex
Aspartate kinase (L-aspartate 4-P-transferase)
Phospholipase B (lysophospholipase) involved in phospholipid metabolism
Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation
Abundant subunit of the nuclear pore complex (NPC)
GTPase, Ras-like GTP binding protein involved in the secretory pathway
Putative transcription factor containing a C2H2 zinc finger
UDP-glucose:sterol glucosyltransferase (Sterol 3-beta-glucosyltransferase)
Deubiquitinating enzyme anchored to the outer mitochondrial membrane
Non-essential protein of unknown function
High-affinity copper transporter of the plasma membrane
Plasma membrane ATP-binding cassette (ABC) transporter
Cyclin-like protein that interacts with Pho85p
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex
Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA
Small subunit of the ribonucleotide-diphosphate reductase (RNR) complex
Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway
Essential ATP-dependent RNA helicase of the DEAD-box protein family
Glucose-repressible ADP-ribosylation factor
SH3 domain protein implicated in the regulation of actin polymerization
Mitochondrial type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity
Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation
Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat
P-loop ATPase with similarity to human OLA1 and bacterial YchF
Copper-binding protein of the mitochondrial inner membrane
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis
Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p)
Putative nucleolar DEAD box RNA helicase
Protein with carboxyl methyl esterase activity
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum
Second-largest subunit of RNA polymerase III
Nuclear type II J heat shock protein of the E. coli dnaJ family
5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39
Hydrophilic protein, involved in vesicle trafficking between the ER and Golgi
Essential protein required for the accumulation of box C/D snoRNA
Essential component of the Rix1 complex (with Rix1p and Ipi3p)
ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex
GTP-binding protein involved in beta-tubulin (Tub2p) folding
Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p)
Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER
Essential nuclear protein with a possible role in the osmoregulatory glycerol response
Mitochondrial protein involved in sorting of proteins in the mitochondria
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase)
Essential nucleolar protein involved in the early steps of 35S rRNA processing
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase
Protein that interacts with Sin3p in a two-hybrid assay
Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis
Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase
Putative methylthio-ribulose-1-phosphate dehydratase
Microtubule-associated protein (MAP) of the XMAP215/Dis1 family
Cytoplasmic thioredoxin isoenzyme of the thioredoxin system
Protein involved in the transcription of 35S rRNA genes by RNA polymerase I
Protein interacting with poly(A)-binding protein Pab1p
Vacuolar transporter chaperon (VTC) involved in distributing V-ATPase and other membrane proteins
Component of the septin ring of the mother-bud neck that is required for cytokinesis
Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway
Golgi-localized protein with homology to gamma-adaptin
Component of the NuA4 histone acetyltransferase complex
One of six ATPases of the 19S regulatory particle of the 26S proteasome
Essential protein involved in nuclear export of Mss4p
RNA polymerase III subunit C160, part of core enzyme
O-glycosylated protein required for cell wall stability
2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family
Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p
Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde
Histidine kinase osmosensor that regulates a MAP kinase cascade
Myosin-like protein associated with the nuclear envelope
Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7)
N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1)
Signal recognition particle (SRP) subunit (homolog of mammalian SRP54)
Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
Protein with an N-terminal kelch-like domain
Transcriptional activator that enhances pseudohyphal growth
Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p
Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase)
Transcription factor involved in glucose repression
High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter
Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation
Acid trehalase required for utilization of extracellular trehalose
Phosphoribosyl-5-amino-1-phosphoribosyl-4- imidazolecarboxiamide isomerase
RNA polymerase II third largest subunit B44, part of central core
Protein containing an Lsm domain, may bind RNA and have a role in RNA processing
Catalytic subunit of the NatB N-terminal acetyltransferase
Peroxisomal adenine nucleotide transporter
Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II
Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria
Nucleoporin, essential subunit of the nuclear pore complex (NPC)
Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling
Protein required for daughter cell separation, multiple mitotic checkpoints and chromosome stability
Subunit alpha of assimilatory sulfite reductase
Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex
One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC)
putative type-III integral membrane protein of unknown function
Mitochondrial protein of unknown function
Gamma subunit of the translation initiation factor eIF2B
Mitochondrial ribosomal protein of the large subunit
Component of the TOM (translocase of outer membrane) complex
Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA
Poly(A)RNA binding protein involved in nuclear mRNA export
Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p)
Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p
Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis
Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase
Guanine nucleotide exchange factor for Gpa1p
Cytosolic serine hydroxymethyltransferase
Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate
Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus
Evolutionarily conserved protein with similarity to Orm2p
Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal protein
Endosomal protein that regulates cell polarity, controls polarized growth
NADPH-dependent alpha-keto amide reductase
Subunit of the core complex of translation initiation factor 3(eIF3)
Subunit of the RNA polymerase II mediator complex
RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF)
Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate
ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-D
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase
Protein required for the hydroxylation of heme O to form heme A
Conserved protein involved in autophagy and the Cvt pathway
AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation
Conserved protein involved in exocytic transport from the Golgi
Mitochondrial inner membrane ATP-binding cassette (ABC) transporter
Member of the Sir2 family of NAD(+)-dependent protein deacetylases
Essential protein involved in transcription regulation
Ribosomal protein lysine methyltransferase
Putative dephospho-CoA kinase (DPCK) that catalyzes the final step in Coenzyme A biosynthesis
Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate
Protein involved in inhibition of translation and nonsense-mediated decay
Protein required for normal intracellular sterol distribution and for sphingolipid metabolism
Carbon source-responsive zinc-finger transcription factor
Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria
Component of the CCR4-NOT transcriptional complex
DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair
Regulatory subunit A of the heterotrimeric protein phosphatase 2A
Peroxisomal ubiquitin conjugating enzyme
Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation
Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex
Protein that induces appearance of [PIN+] prion when overproduced
Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p)
Subunit of the prohibitin complex (Phb1p-Phb2p)
Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit
Protein required for beta-1,6 glucan biosynthesis
Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis
Nucleolar protein, forms a complex with Noc4p
Subunit of the cytosolic chaperonin Cct ring complex
Low-affinity zinc transporter of the plasma membrane
TFIIF (Transcription Factor II) largest subunit
Nonessential protein of unknown function
Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p
Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase
GTP-binding protein of the ras superfamily involved in termination of M-phase
Largest subunit of the origin recognition complex
Non-essential putative integral membrane protein
mRNA transport regulator, essential nuclear protein
Cytosolic aspartate aminotransferase, involved in nitrogen metabolism
Permease of basic amino acids in the vacuolar membrane
Essential nuclear protein involved in early steps of ribosome biogenesis
Splicing factor, component of the U4/U6-U5 snRNP complex
Protein that forms a complex with the Sit4p protein phosphatase and is required for its function
Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p)
Alpha-1,6-mannosyltransferase localized to the ER
Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum
ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport
Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair
Mitochondrial outer membrane protein, component of the Mdm10-Mdm12-Mmm1 complex
Putative chitin transglycosidase, cell wall protein
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation
Mitochondrial intermembrane space protein, forms a complex with TIm8p
Similar to globins and has a functional heme-binding domain
Subunit of the exosome, which is an essential complex present in both nucleus and cytoplasm
Phosphatidylinositol transfer protein (PITP)
Subunit of both RNase MRP and nuclear RNase P
Palmitoylated, plasma membrane-bound casein kinase I isoform
Endoplasmic reticulum (ER) resident protein
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation
NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity
Intracellular sporulation-specific glucoamylase involved in glycogen degradation
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase
Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
Serine/threonine kinase and DNA damage checkpoint effector
Mitochondrial serine hydroxymethyltransferase
Mitochondrial iron transporter of the mitochondrial carrier family (MCF)
Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex
Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance
Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation
B-type cyclin involved in cell cycle progression
Guanine nucleotide exchange factor (GEF)
Putative protein of unknown function, conserved in fungi
Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p)
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-l
Peripherally bound inner membrane protein of the mitochondrial matrix
Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
Putative high affinity iron transporter involved in transport of intravacuolar stores of iron
Non-essential protein of unknown function required for transcriptional induction
Transcriptional activator of genes involved in nitrogen catabolite repression
Plasma membrane localized protein that protects membranes from desiccation
GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p
Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p
Essential protein required for sister chromatid cohesion in mitosis and meiosis
mitochondrial 54S ribosomal protein YmL25
Low affinity vacuolar membrane localized monovalent cation/H+ antiporter
Spermine synthase, required for the biosynthesis of spermine
UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly
Protein integral to the mitochondrial membrane
Karyopherin involved in nuclear import and export
Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secre
S-adenosylmethionine-homocysteine methyltransferase
Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis
putative protein kinase, overexpression causes sensitivity to staurosporine
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA
Beta 5 subunit of the 20S proteasome, responsible for the chymotryptic activity of the proteasome
Putative transporter, member of the mitochondrial carrier family
Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase)
Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p
Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase)
putative component of the Rpd3 histone deacetylase complex
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p
Arginase, responsible for arginine degradation
Mitochondrial succinate-fumarate transporter
Putative lipoate-protein ligase A family member
Sporulation-specific exo-1,3-beta-glucanase
Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p
Essential 70kDa subunit of the exocyst complex
Nucleotide exchange factor for Gsp1p, localizes to the nucleus
Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase)
Protein required for mitochondrial translation
Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase
Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis
Essential conserved protein that is part of the 90S preribosome
GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport
Polypeptide release factor involved in translation termination
Essential nucleolar protein, putative DEAD-box RNA helicase
Inositol monophosphatase, involved in biosynthesis of inositol
Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytos
Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p)
RNA polymerase III subunit C25, required for transcription initiation
Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis
Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2
Alpha subunit of Type II geranylgeranyltransferase
Mitochondrial inner membrane protein required for assembly of the cytochrome c oxidase complex
Auxilin-like protein involved in vesicular transport
Golgi membrane protein involved in manganese homeostasis
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance
Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p
C3HC4-type RING-finger peroxisomal membrane peroxin
Protein required for transcription of rDNA by RNA polymerase I
Protein containing an N-terminal epsin-like domain
Splicing factor associated with the spliceosome
F-box protein component of the SCF ubiquitin-ligase complex
Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose
Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation
Glycerol kinase, converts glycerol to glycerol-3-phosphate
Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia
Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation
Beta subunit of geranylgeranyltransferase type I
Putative mitochondrial transport protein
Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery
Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lys
Nuclear protein related to mammalian high mobility group (HMG) proteins
Essential beta-coat protein of the COPI coatomer
mitochondrial 54S ribosomal protein YmL7/YmL5
Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import
Nucleolar protein involved in the assembly of the large ribosomal subunit
U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis
Vacuolar membrane protein of unknown function involved in vacuolar protein sorting
Protein serine/threonine/tyrosine (dual-specificity) kinase
mitochondrial 37S ribosomal protein YmS18
Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate
Cis-prenyltransferase involved in dolichol synthesis
Polyamine oxidase, converts spermine to spermidine
Protein required for resistance to the antifungal drug ciclopirox olamine
RNA polymerase subunit, common to RNA polymerase I and III
Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p
putative U3 snoRNP protein involved in maturation of pre-18S rRNA
Protein that interacts with silencing proteins at the telomere
Protein required for respiratory growth and stability of the mitochondrial genome
Polyamine transport protein, recognizes spermine, putrescine, and spermidine
Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase
Putative protein-methionine-R-oxide reductase
Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen
mitochondrial 54S ribosomal protein YmL32
Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside
Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)
Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease
Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter
F-box protein involved in recycling plasma membrane proteins internalized by endocytosis
L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine
Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C
Acetylated, cis-golgi localized protein involved in ER to Golgi transport
Specific translational activator for the COX1 mRNA
Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p)
Mitochondrial dicarboxylate carrier, integral membrane protein
Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization
54S ribosomal protein L35, mitochondrial
DNA Polymerase II Epsilon complex with BRCT domain
mitochondrial 54S ribosomal protein YmL37
mitochondrial 54S ribosomal protein YmL23
1-phosphatidylinositol phosphodiesterase
Mitochondrial distribution and morphology protein
Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3
ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97
G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk)
Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration
Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation
TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation
Mitochondrial RNA polymerase specificity factor
Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins
ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p