Saccharomyces cerevisiae S288C chromosome XVI, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome XVI, complete sequence.
sequence version: NC_001148.4
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001148.4
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 9169875
reference: 3
references: 8849441
reference: 4
reference: 5
reference: 6
reference: 7
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006949.\n\nOn Apr 26, 2011 this sequence version replaced NC_001148.3.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 948066
topology: linear
so has quality: SO_0000987
location: 1..948066
location: region:1-948066:1
RO_0002162: 559292

NC_001148
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI
author: Bussey, H.
author: Storms, R.K.
author: Ahmed, A.
author: Albermann, K.
author: Allen, E.
author: Ansorge, W.
author: Araujo, R.
author: Aparicio, A.
author: Barrell, B.
author: Badcock, K.
author: Benes, V.
author: Botstein, D.
author: Bowman, S.
author: Bruckner, M.
author: Carpenter, J.
author: Cherry, J.M.
author: Chung, E.
author: Churcher, C.
author: Coster, F.
author: Davis, K.
author: Davis, R.W.
author: Dietrich, F.S.
author: Delius, H.
author: DiPaolo, T.
author: Hani, J. et al.
journal: Nature 387 (6632 SUPPL), 103-105 (1997)
pubmed: 9169875

9169875
type: PubMed
SIO_000068: pubmed

3
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (16-JAN-2015) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

7
title: Direct Submission
journal: Submitted (14-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:948066:1
position: 948066
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-948066:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: XVI

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL16L; Telomeric region on the left arm of Chromosome XVI; annotated components include an X element core sequence, X element combinatorial repeats, and a long Y' element; TEL16L does have telomeric repeats (TEL16L-TR), but they are missing from the genome annotation due to difficulties encountered during sequencing and/or assembly
so part of: sequence
location: complement(1..7223)
location: region:1-7223:-1
so has part: feature:1-7223:-1:region

S000028933
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:7223:-1
position: 7223
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-7223:-1:region

YPL283C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YRF1
gene: YRF1-7
locus tag: YPL283C
gene synonym: YRF1
so part of: sequence
location: complement(<280..>6007)
location: region:280-6007:-1
so has part: feature:280-6007:-1:exon
subclass of: SO_0000010

855846
type: Gene
SIO_000068: ncbigene

position:280:-1
position: 280
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:6007:-1
position: 6007
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:280-6007:-1:exon

YPL283C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YRF1
gene: YRF1-7
locus tag: YPL283C
gene synonym: YRF1
product: Y' element ATP-dependent helicase protein 1 copy 7
transcript id: NM_001184097.1
SIO_010081: YPL283C
subclass of: SO_0000673
so part of: YPL283C
location: complement(join(<280..5840,5989..>6007))
location: region:280-6007:-1
so has part: feature:5989-6007:-1:exon
so has part: feature:280-5840:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:5989-6007:-1:exon

position:5989:-1
position: 5989
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:280-5840:-1:exon

position:5840:-1
position: 5840
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL283C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YRF1
gene: YRF1-7
locus tag: YPL283C
gene synonym: YRF1
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:genetic interaction:GO:0000722 telomere maintenance via recombination [PMID:9837911]
note: Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
codon start: 1
product: Y' element ATP-dependent helicase protein 1 copy 7
translation: MEIENEQICTCIAQILHLLNSLIITFLDDDKTETGQSFVYIDGFLVKKHNNQHTIVNFETYKNKMKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRGLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGVSVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMIHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
SIO_010081: YPL283C
subclass of: SO_0000673
so part of: YPL283C
location: complement(join(280..5840,5989..6007))
location: region:280-6007:-1
so has part: feature:5989-6007:-1:exon
so has part: feature:280-5840:-1:exon

NP_015040.1
type: Protein
SIO_000068: ncbiprotein

S000006204
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:5989-6007:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:280-5840:-1:exon

YPL282C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU22
locus tag: YPL282C
so part of: sequence
location: complement(<7933..>8427)
location: region:7933-8427:-1
so has part: feature:7933-8427:-1:exon
subclass of: SO_0000010

855847
type: Gene
SIO_000068: ncbigene

position:7933:-1
position: 7933
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:8427:-1
position: 8427
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7933-8427:-1:exon

YPL282C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU22
locus tag: YPL282C
product: seripauperin PAU22
transcript id: NM_001184096.1
SIO_010081: YPL282C
subclass of: SO_0000673
so part of: YPL282C
location: complement(<7933..>8427)
location: region:7933-8427:-1
so has part: feature:7933-8427:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:7933-8427:-1:exon

YPL282C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU22
locus tag: YPL282C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: hypothetical protein; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole; identical to Pau21p; encodes two proteins that are translated from two different start codons
codon start: 1
product: seripauperin PAU22
translation: MTNEGIGINRDTSTICLREYVFIHFFPVKLISALTNKTNTMVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVSDIRAHLAQYYLFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTRLRPAISSALSKDGIYTAIPK
SIO_010081: YPL282C
subclass of: SO_0000673
so part of: YPL282C
location: complement(7933..8427)
location: region:7933-8427:-1
so has part: feature:7933-8427:-1:exon

NP_015041.1
type: Protein
SIO_000068: ncbiprotein

S000006203
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:7933-8427:-1:exon

YPL281C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERR2
locus tag: YPL281C
so part of: sequence
location: complement(<9557..>10870)
location: region:9557-10870:-1
so has part: feature:9557-10870:-1:exon
subclass of: SO_0000010

855848
type: Gene
SIO_000068: ncbigene

position:9557:-1
position: 9557
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:10870:-1
position: 10870
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9557-10870:-1:exon

YPL281C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERR2
locus tag: YPL281C
product: phosphopyruvate hydratase ERR2
transcript id: NM_001184095.1
SIO_010081: YPL281C
subclass of: SO_0000673
so part of: YPL281C
location: complement(<9557..>10870)
location: region:9557-10870:-1
so has part: feature:9557-10870:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9557-10870:-1:exon

YPL281C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERR2
locus tag: YPL281C
EC number: 4.2.1.11
experiment: EXISTENCE:direct assay:GO:0004634 phosphopyruvate hydratase activity [PMID:23359425]
experiment: EXISTENCE:genetic interaction:GO:0004634 phosphopyruvate hydratase activity [PMID:23359425]
note: Enolase, a phosphopyruvate hydratase; catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate; complements the growth defect of an ENO1 ENO2 double mutant
codon start: 1
product: phosphopyruvate hydratase ERR2
translation: MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL
SIO_010081: YPL281C
subclass of: SO_0000673
so part of: YPL281C
location: complement(9557..10870)
location: region:9557-10870:-1
so has part: feature:9557-10870:-1:exon

NP_015042.1
type: Protein
SIO_000068: ncbiprotein

S000006202
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:9557-10870:-1:exon

YPL280W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HSP32
locus tag: YPL280W
so part of: sequence
location: <11887..>12600
location: region:11887-12600:1
so has part: feature:11887-12600:1:exon
subclass of: SO_0000010

855849
type: Gene
SIO_000068: ncbigene

position:11887:1
position: 11887
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:12600:1
position: 12600
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11887-12600:1:exon

YPL280W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HSP32
locus tag: YPL280W
product: glutathione-independent methylglyoxalase family protein
transcript id: NM_001184094.1
SIO_010081: YPL280W
subclass of: SO_0000673
so part of: YPL280W
location: <11887..>12600
location: region:11887-12600:1
so has part: feature:11887-12600:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11887-12600:1:exon

YPL280W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HSP32
locus tag: YPL280W
EC number: 4.2.1.130
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:24706893]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:24706893|PMID:26777405]
experiment: EXISTENCE:genetic interaction:GO:0051596 methylglyoxal catabolic process [PMID:27984092]
experiment: EXISTENCE:mutant phenotype:GO:0031669 cellular response to nutrient levels [PMID:24706893]
note: Possible chaperone and cysteine protease; required for transcriptional reprogramming during the diauxic shift and for survival in stationary phase; similar to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer
codon start: 1
product: glutathione-independent methylglyoxalase family protein
translation: MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNGAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS
SIO_010081: YPL280W
subclass of: SO_0000673
so part of: YPL280W
location: 11887..12600
location: region:11887-12600:1
so has part: feature:11887-12600:1:exon

NP_015043.1
type: Protein
SIO_000068: ncbiprotein

S000006201
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11887-12600:1:exon

YPL279C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FEX2
locus tag: YPL279C
so part of: sequence
location: complement(<13228..>14355)
location: region:13228-14355:-1
so has part: feature:13228-14355:-1:exon
subclass of: SO_0000010

855850
type: Gene
SIO_000068: ncbigene

position:13228:-1
position: 13228
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:14355:-1
position: 14355
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13228-14355:-1:exon

YPL279C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FEX2
locus tag: YPL279C
product: fluoride transporter
transcript id: NM_001184093.1
SIO_010081: YPL279C
subclass of: SO_0000673
so part of: YPL279C
location: complement(<13228..>14355)
location: region:13228-14355:-1
so has part: feature:13228-14355:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:13228-14355:-1:exon

YPL279C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FEX2
locus tag: YPL279C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:26055717]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:1903424 fluoride transmembrane transport [PMID:24173035|PMID:26055717]
experiment: EXISTENCE:genetic interaction:GO:1903425 fluoride transmembrane transporter activity [PMID:24173035]
experiment: EXISTENCE:mutant phenotype:GO:1903424 fluoride transmembrane transport [PMID:26055717]
note: Protein involved in fluoride export; nearly identical to FEX1, and deletion of both proteins results in a large increase in fluoride sensitivity compared with the single mutant; contains two FEX domains connected by a linker; part of a widespread family of conserved fluoride export proteins
codon start: 1
product: fluoride transporter
translation: MIFNPVISNHKLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLNAYTWMKDHQVLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTKLPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENAGDVDTQEMEKNILEFKFKTPAPFFKKFFDVVDKLAYALAFPLIILFVVLCAYYENYSRGKWTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTDIPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIGISYCLLVITLGSYAWTRGLTNPIC
SIO_010081: YPL279C
subclass of: SO_0000673
so part of: YPL279C
location: complement(13228..14355)
location: region:13228-14355:-1
so has part: feature:13228-14355:-1:exon

NP_015044.1
type: Protein
SIO_000068: ncbiprotein

S000006200
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:13228-14355:-1:exon

YPL278C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL278C
so part of: sequence
location: complement(<15053..>15355)
location: region:15053-15355:-1
so has part: feature:15053-15355:-1:exon
subclass of: SO_0000010

855851
type: Gene
SIO_000068: ncbigene

position:15053:-1
position: 15053
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:15355:-1
position: 15355
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:15053-15355:-1:exon

YPL278C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL278C
product: uncharacterized protein
transcript id: NM_001184092.1
SIO_010081: YPL278C
subclass of: SO_0000673
so part of: YPL278C
location: complement(<15053..>15355)
location: region:15053-15355:-1
so has part: feature:15053-15355:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:15053-15355:-1:exon

YPL278C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL278C
note: hypothetical protein; gene expression regulated by copper levels
codon start: 1
product: uncharacterized protein
translation: MTDNTTSSDLIKNVETARSTIDGLIESLGWIELNYRCERQCNWDEVCYTPSWGPSPMGMTEPGSHNEGFGTHFDESRQRLVINSKLQCININDLMVNRNH
SIO_010081: YPL278C
subclass of: SO_0000673
so part of: YPL278C
location: complement(15053..15355)
location: region:15053-15355:-1
so has part: feature:15053-15355:-1:exon

NP_015045.1
type: Protein
SIO_000068: ncbiprotein

S000006199
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:15053-15355:-1:exon

YPL277C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL277C
so part of: sequence
location: complement(<15405..>16868)
location: region:15405-16868:-1
so has part: feature:15405-16868:-1:exon
subclass of: SO_0000010

855852
type: Gene
SIO_000068: ncbigene

position:15405:-1
position: 15405
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:16868:-1
position: 16868
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:15405-16868:-1:exon

YPL277C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL277C
product: uncharacterized protein
transcript id: NM_001184091.1
SIO_010081: YPL277C
subclass of: SO_0000673
so part of: YPL277C
location: complement(<15405..>16868)
location: region:15405-16868:-1
so has part: feature:15405-16868:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:15405-16868:-1:exon

YPL277C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL277C
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11935221]
note: hypothetical protein; localized to the membranes; gene expression regulated by copper levels
codon start: 1
product: uncharacterized protein
translation: MRFHRQGISAIIGVLLIVLLGFCWKLSGSYGIVSTALPHNQSAIKSTDLPSIRWDNYHEFVRDIDFDNSTAIFNSIRAALRQSPSDIHPVGVSYFPAVIPKGTLMYHAGSKVPTTFEWLAMDHEFSYSFGLRSPSYGRKSLERRHGRFGNGTNGDHPKGPPPPPPPPDEKGRGSQKMLTYRAARDLNKFLYLDGASAAKTDSGEMDTQLMLSNVIKEKLNLTDDGENERMAERLYAARICKWGKPFGLDGIIRVEVGFEVVLCDFSADNVELVSMLEMVQPNQYLGLPAPTVISKEEGWPLDENGSLVEDQLTDDQKAILEREDGWEKAFSNFNAVKSFNQLRAGAAHDNGEHRIHIDYRYLVSGINRTYIAPDPNNRRLLDEGMTWEKQLDMVDDLEKALEVGFDATQSMDWQLAFDELVLKFAPLLKSVSNILNSDGDINESIAINATALTLNFCLPICEPIPGLKNGCRLFDLVICCQRCRRNC
SIO_010081: YPL277C
subclass of: SO_0000673
so part of: YPL277C
location: complement(15405..16868)
location: region:15405-16868:-1
so has part: feature:15405-16868:-1:exon

NP_015046.1
type: Protein
SIO_000068: ncbiprotein

S000006198
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:15405-16868:-1:exon

YPL276W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FDH2
locus tag: YPL276W
gene synonym: FDH2
experiment: EXISTENCE:genetic interaction:GO:0008863 formate dehydrogenase (NAD+) activity [PMID:11921099]
experiment: EXISTENCE:genetic interaction:GO:0042183 formate catabolic process [PMID:11921099|PMID:19564482]
note: NAD(+)-dependent formate dehydrogenase; may protect cells from exogenous formate; YPL275W and YPL276W comprise a continuous open reading frame in some S. cerevisiae strains but not in the genomic reference strain S288C
pseudo: true
so part of: sequence
location: 17948..18385
location: region:17948-18385:1
so has part: feature:17948-18385:1:exon

2827705
type: Gene
SIO_000068: ncbigene

S000006197
type: SGD
SIO_000068: sgd

position:17948:1
position: 17948
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:18385:1
position: 18385
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:17948-18385:1:exon

YPL276W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FDH2
locus tag: YPL276W
gene synonym: FDH2
pseudo: true
SIO_010081: YPL276W
subclass of: SO_0000673
so part of: YPL276W
location: 17948..18385
location: region:17948-18385:1
so has part: feature:17948-18385:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:17948-18385:1:exon

YPL275W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FDH2
locus tag: YPL275W
experiment: EXISTENCE:genetic interaction:GO:0008863 formate dehydrogenase (NAD+) activity [PMID:11921099]
experiment: EXISTENCE:genetic interaction:GO:0042183 formate catabolic process [PMID:11921099|PMID:19564482]
note: NAD(+)-dependent formate dehydrogenase; may protect cells from exogenous formate; YPL275W and YPL276W comprise a continuous open reading frame in some S. cerevisiae strains but not in the genomic reference strain S288C
pseudo: true
so part of: sequence
location: 18369..19079
location: region:18369-19079:1
so has part: feature:18369-19079:1:exon

855853
type: Gene
SIO_000068: ncbigene

S000006196
type: SGD
SIO_000068: sgd

position:18369:1
position: 18369
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:19079:1
position: 19079
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:18369-19079:1:exon

YPL275W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FDH2
locus tag: YPL275W
pseudo: true
SIO_010081: YPL275W
subclass of: SO_0000673
so part of: YPL275W
location: 18369..19079
location: region:18369-19079:1
so has part: feature:18369-19079:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:18369-19079:1:exon

YPL275W
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
gene: FDH2
locus tag: YPL275W
note: ARS1603; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
pseudo: true
SIO_010081: YPL275W
subclass of: SO_0000673
so part of: YPL275W
location: 18370..19069
location: region:18370-19069:1
so has part: feature:18370-19069:1:exon

S000130195
type: SGD
SIO_000068: sgd

position:18370:1
position: 18370
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:19069:1
position: 19069
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:18370-19069:1:exon

YPL274W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAM3
locus tag: YPL274W
so part of: sequence
location: <22938..>24701
location: region:22938-24701:1
so has part: feature:22938-24701:1:exon
subclass of: SO_0000010

855854
type: Gene
SIO_000068: ncbigene

position:22938:1
position: 22938
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:24701:1
position: 24701
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:22938-24701:1:exon

YPL274W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAM3
locus tag: YPL274W
product: bifunctional polyamine/amino acid permease SAM3
transcript id: NM_001184088.1
SIO_010081: YPL274W
subclass of: SO_0000673
so part of: YPL274W
location: <22938..>24701
location: region:22938-24701:1
so has part: feature:22938-24701:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:22938-24701:1:exon

YPL274W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAM3
locus tag: YPL274W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:17218313]
experiment: EXISTENCE:direct assay:GO:0015489 putrescine transmembrane transporter activity [PMID:17218313]
experiment: EXISTENCE:direct assay:GO:0015606 spermidine transmembrane transporter activity [PMID:17218313]
experiment: EXISTENCE:direct assay:GO:0015847 putrescine transport [PMID:17218313]
experiment: EXISTENCE:direct assay:GO:0015848 spermidine transport [PMID:17218313]
experiment: EXISTENCE:mutant phenotype:GO:0000095 S-adenosyl-L-methionine transmembrane transporter activity [PMID:10497160]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:10497160]
experiment: EXISTENCE:mutant phenotype:GO:0015489 putrescine transmembrane transporter activity [PMID:17218313]
experiment: EXISTENCE:mutant phenotype:GO:0015606 spermidine transmembrane transporter activity [PMID:17218313]
experiment: EXISTENCE:mutant phenotype:GO:0015805 S-adenosyl-L-methionine transport [PMID:10497160]
experiment: EXISTENCE:mutant phenotype:GO:0015847 putrescine transport [PMID:17218313]
experiment: EXISTENCE:mutant phenotype:GO:0015848 spermidine transport [PMID:17218313]
note: High-affinity S-adenosylmethionine permease; required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p
codon start: 1
product: bifunctional polyamine/amino acid permease SAM3
translation: MDILKRGNESDKFTKIETESTTIPNDSDRSGSLIRRMKDSFKQSNLHVIPEDLENSEQTEQEKIQWKLASQPYQKVLSQRHLTMIAIGGTLGTGLFIGLGYSLASGPAALLIGFLLVGTSMFCVVQSAAELSCQFPVSGSYATHVSRFIDESVGFTVATNYALAWLISFPSELIGCALTISYWNQTVNPAVWVAIFYVFIMVLNLFGVRGFAETEFALSIIKVIAIFIFIIIGIVLIAGGGPNSTGYIGAKYWHDPGAFAKPVFKNLCNTFVSAAFSFGGSELVLLTSTESKNISAISRAAKGTFWRIAIFYITTVVIIGCLVPYNDPRLLSGSNSEDVSASPFVIALSNTGSMGAKVSNFMNVVILVAVVSVCNSCVYASSRLIQALGASGQLPSVCSYMDRKGRPLVGIGISGAFGLLGFLVASKKEDEVFTWLFALCSISSFFTWFCICMSQIRFRMALKAQGRSNDEIAYKSILGVYGGILGCVLNALLIAGEIYVSAAPVGSPSSAEAFFEYCLSIPIMIVVYFAHRFYRRDWKHFYIKRSEIDLDTGCSVENLELFKAQKEAEEQLIASKPFYYKIYRFWC
SIO_010081: YPL274W
subclass of: SO_0000673
so part of: YPL274W
location: 22938..24701
location: region:22938-24701:1
so has part: feature:22938-24701:1:exon

NP_015049.1
type: Protein
SIO_000068: ncbiprotein

S000006195
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:22938-24701:1:exon

YPL273W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAM4
locus tag: YPL273W
so part of: sequence
location: <25087..>26064
location: region:25087-26064:1
so has part: feature:25087-26064:1:exon
subclass of: SO_0000010

855855
type: Gene
SIO_000068: ncbigene

position:25087:1
position: 25087
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:26064:1
position: 26064
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:25087-26064:1:exon

YPL273W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAM4
locus tag: YPL273W
product: S-adenosylmethionine-homocysteine S-methyltransferase SAM4
transcript id: NM_001184087.1
SIO_010081: YPL273W
subclass of: SO_0000673
so part of: YPL273W
location: <25087..>26064
location: region:25087-26064:1
so has part: feature:25087-26064:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:25087-26064:1:exon

YPL273W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAM4
locus tag: YPL273W
EC number: 2.1.1.10
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity [PMID:11013242]
experiment: EXISTENCE:direct assay:GO:0019284 L-methionine salvage from S-adenosylmethionine [PMID:14189892]
experiment: EXISTENCE:direct assay:GO:0046498 S-adenosylhomocysteine metabolic process [PMID:14189892]
experiment: EXISTENCE:direct assay:GO:0050667 homocysteine metabolic process [PMID:14189892]
note: S-adenosylmethionine-homocysteine methyltransferase; functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio; SAM4 has a paralog, YMR321C, that arose from a single-locus duplication
codon start: 1
product: S-adenosylmethionine-homocysteine S-methyltransferase SAM4
translation: MARLPLKQFLADNPKKVLVLDGGQGTELENRGIKVANPVWSTIPFISESFWSDESSANRKIVKEMFNDFLNAGAEILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFSRNCIGEDKYLIGCIGPWGAHICREFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPNIHELKAILSWDESILSRPFYIGLSVHEHGVLRDGTTMEEIAQVIKDLGDKINPNFSFLGINCVSFNQSPDILESLHQALPNMALLAYPNSGEVYDTEKKIWLPNSDKLNSWDTVVKQYISSGARIIGGCCRTSPKDIQEISAAVKKYT
SIO_010081: YPL273W
subclass of: SO_0000673
so part of: YPL273W
location: 25087..26064
location: region:25087-26064:1
so has part: feature:25087-26064:1:exon

NP_015050.1
type: Protein
SIO_000068: ncbiprotein

S000006194
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:25087-26064:1:exon

YPL272C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PBI1
locus tag: YPL272C
so part of: sequence
location: complement(<26611..>28164)
location: region:26611-28164:-1
so has part: feature:26611-28164:-1:exon
subclass of: SO_0000010

855856
type: Gene
SIO_000068: ncbigene

position:26611:-1
position: 26611
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:28164:-1
position: 28164
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:26611-28164:-1:exon

YPL272C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PBI1
locus tag: YPL272C
product: Pbi1p
transcript id: NM_001184086.1
SIO_010081: YPL272C
subclass of: SO_0000673
so part of: YPL272C
location: complement(<26611..>28164)
location: region:26611-28164:-1
so has part: feature:26611-28164:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:26611-28164:-1:exon

YPL272C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PBI1
locus tag: YPL272C
note: hypothetical protein; gene expression induced in response to ketoconazole; YPL272C is not an essential gene
codon start: 1
product: Pbi1p
translation: MTTFRPLSSFEKKILTQSLNDQRNGTIFSSTYSKSLSRENDADWHSDEVTLGTNSSKDDSRLTLPLIATTLKRLIKSQPALFATVNEEWEFEPLKQLKTSDIVNVIEFETIKDKEVNCHWGVPPPYLLRHAFNKTRFVPGSNKPLWTLYVIDEALLVFHGHDVLFDIFSAANFHKLFLKELNEISTVTHSEDRILFDVNDINLSELKFPKSIYDSAKLHLPAMTPQIFHKQTQSFFKSIYYNTLKRPFGYLTNQTSLSSSVSATQLKKYNDILNAHTSLCGTTVFGIVNNQRFNYLKSIVNQEHICLRSFICGIAMICLKPLVKDFSGTIVFTIPINLRNHLGLGGSLGLFFKELRVECPLSLIDDELSANEFLTNSNDNEDNDDEFNERLMEYQFNKVTKHVSGFIMAKLRSWEKNGFNDDDIRRMKYDNDDDFHIQNSRTKLIQINDVSDISLSMNGDDKSFKIVSTGFTSSINRPTLMSLSYTYCEEMGLNICIHYPDSYNLESFVECFESFIE
SIO_010081: YPL272C
subclass of: SO_0000673
so part of: YPL272C
location: complement(26611..28164)
location: region:26611-28164:-1
so has part: feature:26611-28164:-1:exon

NP_015051.1
type: Protein
SIO_000068: ncbiprotein

S000006193
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:26611-28164:-1:exon

YPL271W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATP15
locus tag: YPL271W
so part of: sequence
location: <30079..>30267
location: region:30079-30267:1
so has part: feature:30079-30267:1:exon
subclass of: SO_0000010

855857
type: Gene
SIO_000068: ncbigene

position:30079:1
position: 30079
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:30267:1
position: 30267
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30079-30267:1:exon

YPL271W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATP15
locus tag: YPL271W
product: F1F0 ATP synthase subunit epsilon
transcript id: NM_001184085.1
SIO_010081: YPL271W
subclass of: SO_0000673
so part of: YPL271W
location: <30079..>30267
location: region:30079-30267:1
so has part: feature:30079-30267:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:30079-30267:1:exon

YPL271W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATP15
locus tag: YPL271W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk [PMID:17082766]
experiment: EXISTENCE:direct assay:GO:0015986 proton motive force-driven ATP synthesis [PMID:20691145]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:15294286|PMID:18722382]
experiment: EXISTENCE:direct assay:GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) [PMID:15294286]
experiment: EXISTENCE:direct assay:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:20691145]
experiment: EXISTENCE:mutant phenotype:GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk [PMID:8416924]
experiment: EXISTENCE:mutant phenotype:GO:0015986 proton motive force-driven ATP synthesis [PMID:8416924]
experiment: EXISTENCE:mutant phenotype:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:8416924]
note: Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated
codon start: 1
product: F1F0 ATP synthase subunit epsilon
translation: MSAWRKAGISYAAYLNVAAQAIRSSLKTELQTASVLNRSQTDAFYTQYKNGTAASEPTPITK
SIO_010081: YPL271W
subclass of: SO_0000673
so part of: YPL271W
location: 30079..30267
location: region:30079-30267:1
so has part: feature:30079-30267:1:exon

NP_015052.1
type: Protein
SIO_000068: ncbiprotein

S000006192
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:30079-30267:1:exon

YPL270W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MDL2
locus tag: YPL270W
so part of: sequence
location: <30482..>32803
location: region:30482-32803:1
so has part: feature:30482-32803:1:exon
subclass of: SO_0000010

855858
type: Gene
SIO_000068: ncbigene

position:30482:1
position: 30482
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:32803:1
position: 32803
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30482-32803:1:exon

YPL270W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MDL2
locus tag: YPL270W
product: ATP-binding cassette permease MDL2
transcript id: NM_001184084.1
SIO_010081: YPL270W
subclass of: SO_0000673
so part of: YPL270W
location: <30482..>32803
location: region:30482-32803:1
so has part: feature:30482-32803:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:30482-32803:1:exon

YPL270W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MDL2
locus tag: YPL270W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:11251115]
experiment: EXISTENCE:direct assay:GO:0005774 vacuolar membrane [PMID:23509072]
experiment: EXISTENCE:direct assay:GO:0070301 cellular response to hydrogen peroxide [PMID:23509072]
note: Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis
codon start: 1
product: ATP-binding cassette permease MDL2
translation: MLNGRLPLLRLGICRNMLSRPRLAKLPSIRFRSLVTPSSSQLIPLSRLCLRSPAVGKSLILQSFRCNSSKTVPETSLPSASPISKGSARSAHAKEQSKTDDYKDIIRLFMLAKRDWKLLLTAILLLTISCSIGMSIPKVIGIVLDTLKTSSGSDFFDLKIPIFSLPLYEFLSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPDRGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNEKAAPGPSDQQLQIEKVIEKEDLNESKEHDDQKKDDNDDNDNNHDNDSNNQSPETKDNNSDDIEKSVEHLLKDAAKEANPIKITPQP
SIO_010081: YPL270W
subclass of: SO_0000673
so part of: YPL270W
location: 30482..32803
location: region:30482-32803:1
so has part: feature:30482-32803:1:exon

NP_015053.2
type: Protein
SIO_000068: ncbiprotein

S000006191
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:30482-32803:1:exon

YPL269W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KAR9
locus tag: YPL269W
so part of: sequence
location: <33013..>34947
location: region:33013-34947:1
so has part: feature:33013-34947:1:exon
subclass of: SO_0000010

855859
type: Gene
SIO_000068: ncbigene

position:33013:1
position: 33013
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:34947:1
position: 34947
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:33013-34947:1:exon

YPL269W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KAR9
locus tag: YPL269W
product: Kar9p
transcript id: NM_001184083.1
SIO_010081: YPL269W
subclass of: SO_0000673
so part of: YPL269W
location: <33013..>34947
location: region:33013-34947:1
so has part: feature:33013-34947:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:33013-34947:1:exon

YPL269W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KAR9
locus tag: YPL269W
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:26906737]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26906737]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:26906737]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:20534809]
experiment: EXISTENCE:direct assay:GO:0005881 cytoplasmic microtubule [PMID:26906737]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:9442113]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:9442113]
experiment: EXISTENCE:genetic interaction:GO:0031578 mitotic spindle orientation checkpoint signaling [PMID:24850890]
experiment: EXISTENCE:mutant phenotype:GO:0030473 nuclear migration along microtubule [PMID:9442113]
experiment: EXISTENCE:mutant phenotype:GO:0051293 establishment of spindle localization [PMID:22385961]
note: Spindle positioning factor; orients astral microtubules, connecting them to actin cables at the cortex with Bim1p and Myo2, resulting in proper spindle positioning; targeted for StuBL-dependent degradation at kinetochores by Slx5p-Slx8p, ensuring chromosome transmission fidelity and correct spindle positioning; role in karyogamy; localizes to the shmoo tip, the growing bud-tip, the nucleus, the kinetochore, the spindle and microtubules; homolog of adenomatous polyposis coli
codon start: 1
product: Kar9p
translation: MDNDGPRSMTIGDDFQENFCERLERIHNTLHSINDCNSLNESTTSISETLLVQFYDDLENVASVIPDLVNKKRLGKDDILLFMDWLLLKKYMLYQFISDVHNIEEGFAHLLDLLEDEFSKDDQDSDKYNRFSPMFDVIEESTQIKTQLEPWLTNLKELLDTSLEFNEISKDHMDTLHKIINSNISYCLEIQEERFASPIRHTPSFTLEQLVKLLGTHTETTEPKVPKFSPAEDILSRKFLNLKKNIPPIEKSLTDILPQRIVQFGHRNITNITTLQTILQKKYELIMKDYRFMNSEFRELKVELIDKRWNILFINLNHELLYILDEIERLQSKLLTTKYTKDITIRLERQLERKSKTVSKTFNIIYRALEFSLLDAGVASKTNELAQRWLNIKPTADKILIKSSASNKIATSKKKIPKPKSLGFGRPNSVIGTITQDFQERVAINEGDSNKTPENSTTVALKGKKLGKALLQKMNIKPATSPNSSNAINPFFDPESPNKGKLILSSVPPLPYDETDETTLRVSRGENEKSPDSFITSRHENKVQITETPLMAKNKSVLDIEKDKWNHYRSLPSRIPIYKDKVVKVTVENTPIAKVFQTPPTKITTPNSQVWVPSTRRRTRLRPPTPLSQLLSPREGRLDKTPTY
SIO_010081: YPL269W
subclass of: SO_0000673
so part of: YPL269W
location: 33013..34947
location: region:33013-34947:1
so has part: feature:33013-34947:1:exon

NP_015054.1
type: Protein
SIO_000068: ncbiprotein

S000006190
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:33013-34947:1:exon

YPL268W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PLC1
locus tag: YPL268W
so part of: sequence
location: <35236..>37845
location: region:35236-37845:1
so has part: feature:35236-37845:1:exon
subclass of: SO_0000010

855860
type: Gene
SIO_000068: ncbigene

position:35236:1
position: 35236
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:37845:1
position: 37845
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35236-37845:1:exon

YPL268W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PLC1
locus tag: YPL268W
product: phosphatidylinositol phospholipase C
transcript id: NM_001184082.1
SIO_010081: YPL268W
subclass of: SO_0000673
so part of: YPL268W
location: <35236..>37845
location: region:35236-37845:1
so has part: feature:35236-37845:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:35236-37845:1:exon

YPL268W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PLC1
locus tag: YPL268W
EC number: 3.1.4.11
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:10779349|PMID:12756538]
experiment: EXISTENCE:direct assay:GO:0004435 phosphatidylinositol phospholipase C activity [PMID:15485855|PMID:8395015]
experiment: EXISTENCE:direct assay:GO:0009395 phospholipid catabolic process [PMID:8395015]
experiment: EXISTENCE:genetic interaction:GO:0001402 signal transduction involved in filamentous growth [PMID:10514491]
experiment: EXISTENCE:mutant phenotype:GO:0004435 phosphatidylinositol phospholipase C activity [PMID:7753023|PMID:9784626]
experiment: EXISTENCE:mutant phenotype:GO:0009395 phospholipid catabolic process [PMID:7753023]
experiment: EXISTENCE:mutant phenotype:GO:0032958 inositol phosphate biosynthetic process [PMID:10390371]
experiment: EXISTENCE:mutant phenotype:GO:0034501 protein localization to kinetochore [PMID:19205744]
experiment: EXISTENCE:physical interaction:GO:0000776 kinetochore [PMID:10779349]
experiment: EXISTENCE:physical interaction:GO:0001402 signal transduction involved in filamentous growth [PMID:10514491]
note: Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation
codon start: 1
product: phosphatidylinositol phospholipase C
translation: MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENGPVVCHGFLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTDKLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL
SIO_010081: YPL268W
subclass of: SO_0000673
so part of: YPL268W
location: 35236..37845
location: region:35236-37845:1
so has part: feature:35236-37845:1:exon

NP_015055.1
type: Protein
SIO_000068: ncbiprotein

S000006189
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:35236-37845:1:exon

YPL267W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ACM1
locus tag: YPL267W
so part of: sequence
location: <38169..>38798
location: region:38169-38798:1
so has part: feature:38169-38798:1:exon
subclass of: SO_0000010

855861
type: Gene
SIO_000068: ncbigene

position:38169:1
position: 38169
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38798:1
position: 38798
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:38169-38798:1:exon

YPL267W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ACM1
locus tag: YPL267W
product: Acm1p
transcript id: NM_001184081.1
SIO_010081: YPL267W
subclass of: SO_0000673
so part of: YPL267W
location: <38169..>38798
location: region:38169-38798:1
so has part: feature:38169-38798:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:38169-38798:1:exon

YPL267W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ACM1
locus tag: YPL267W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18498748]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18498748]
experiment: EXISTENCE:direct assay:GO:0055105 ubiquitin-protein transferase inhibitor activity [PMID:18498748|PMID:18519589|PMID:18596038]
experiment: EXISTENCE:direct assay:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:18519589|PMID:18596038]
experiment: EXISTENCE:genetic interaction:GO:0055105 ubiquitin-protein transferase inhibitor activity [PMID:18498748]
experiment: EXISTENCE:genetic interaction:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:17030612|PMID:18519589|PMID:18596038]
experiment: EXISTENCE:mutant phenotype:GO:0055105 ubiquitin-protein transferase inhibitor activity [PMID:18498748|PMID:18596038]
experiment: EXISTENCE:mutant phenotype:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:18596038|PMID:18519589]
experiment: EXISTENCE:physical interaction:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:18519589|PMID:18596038]
note: Pseudosubstrate inhibitor of the APC/C; suppresses APC/C [Cdh1]-mediated proteolysis of mitotic cyclins; associates with Cdh1p, Bmh1p and Bmh2p; cell cycle regulated protein; the anaphase-promoting complex/cyclosome is also known as APC/C
codon start: 1
product: Acm1p
translation: MISPSKKRTILSSKNINQKPRAVVKGNELRSPSKRRSQIDTDYALRRSPIKTIQISKAAQFMLYEETAEERNIAVHRHNEIYNNNNSVSNENNPSQVKENLSPAKICPYERAFLREGGRIALKDLSVDEFKGYIQDPLTDETIPLTLPLGDKKISLPSFITPPRNSKISIFFTSKHQGQNPETKISRSTDDVSEKKVVRKLSFHVYEDE
SIO_010081: YPL267W
subclass of: SO_0000673
so part of: YPL267W
location: 38169..38798
location: region:38169-38798:1
so has part: feature:38169-38798:1:exon

NP_015056.1
type: Protein
SIO_000068: ncbiprotein

S000006188
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:38169-38798:1:exon

YPL266W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDH1
gene: DIM1
locus tag: YPL266W
gene synonym: CDH1
so part of: sequence
location: <39121..>40077
location: region:39121-40077:1
so has part: feature:39121-40077:1:exon
subclass of: SO_0000010

855862
type: Gene
SIO_000068: ncbigene

position:39121:1
position: 39121
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:40077:1
position: 40077
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39121-40077:1:exon

YPL266W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDH1
gene: DIM1
locus tag: YPL266W
gene synonym: CDH1
product: putative dimethyladenosine transferase
transcript id: NM_001184080.1
SIO_010081: YPL266W
subclass of: SO_0000673
so part of: YPL266W
location: <39121..>40077
location: region:39121-40077:1
so has part: feature:39121-40077:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:39121-40077:1:exon

YPL266W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDH1
gene: DIM1
locus tag: YPL266W
gene synonym: CDH1
EC number: 2.1.1.183
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:15167894]
experiment: EXISTENCE:mutant phenotype:GO:0000154 rRNA modification [PMID:8064863]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:8064863]
note: Essential 18S rRNA dimethylase (dimethyladenosine transferase); responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing; human homolog DIMT1 complements yeast dim1 mutant
codon start: 1
product: putative dimethyladenosine transferase
translation: MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLAMNNEMVDDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS
SIO_010081: YPL266W
subclass of: SO_0000673
so part of: YPL266W
location: 39121..40077
location: region:39121-40077:1
so has part: feature:39121-40077:1:exon

NP_015057.1
type: Protein
SIO_000068: ncbiprotein

S000006187
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:39121-40077:1:exon

YPL265W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DIP5
locus tag: YPL265W
so part of: sequence
location: <41043..>42869
location: region:41043-42869:1
so has part: feature:41043-42869:1:exon
subclass of: SO_0000010

855863
type: Gene
SIO_000068: ncbigene

position:41043:1
position: 41043
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:42869:1
position: 42869
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:41043-42869:1:exon

YPL265W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DIP5
locus tag: YPL265W
product: dicarboxylic amino acid permease
transcript id: NM_001184079.1
SIO_010081: YPL265W
subclass of: SO_0000673
so part of: YPL265W
location: <41043..>42869
location: region:41043-42869:1
so has part: feature:41043-42869:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:41043-42869:1:exon

YPL265W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DIP5
locus tag: YPL265W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005310 dicarboxylic acid transmembrane transporter activity [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0006865 amino acid transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Dicarboxylic amino acid permease; mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly; relocalizes from plasma membrane to vacuole upon DNA replication stress
codon start: 1
product: dicarboxylic amino acid permease
translation: MKMPLKKMFTSTSPRNSSSLDSDHDAYYSKQNPDNFPVKEQEIYNIDLEENNVSSRSSTSTSPSARDDSFAVPDGKDENTRLRKDLKARHISMIAIGGSLGTGLLIGTGTALLTGGPVAMLIAYAFVGLLVFYTMACLGEMASYIPLDGFTSYASRYVDPALGFAIGYTYLFKYFILPPNQLTAAALVIQYWISRDRVNPGVWITIFLVVIVAINVVGVKFFGEFEFWLSSFKVMVMLGLILLLFIIMLGGGPNHDRLGFRYWRDPGAFKEYSTAITGGKGKFVSFVAVFVYSLFSYTGIELTGIVCSEAENPRKSVPKAIKLTVYRIIVFYLCTVFLLGMCVAYNDPRLLSTKGKSMSAAASPFVVAIQNSGIEVLPHIFNACVLVFVFSACNSDLYVSSRNLYALAIDGKAPKIFAKTSRWGVPYNALILSVLFCGLAYMNVSSGSAKIFNYFVNVVSMFGILSWITILIVYIYFDKACRAQGIDKSKFAYVAPGQRYGAYFALFFCILIALIKNFTVFLGHKFDYKTFITGYIGLPVYIISWAGYKLIYKTKVIKSTDVDLYTFKEIYDREEEEGRMKDQEKEERLKSNGKNMEWFYEKFLGNIF
SIO_010081: YPL265W
subclass of: SO_0000673
so part of: YPL265W
location: 41043..42869
location: region:41043-42869:1
so has part: feature:41043-42869:1:exon

NP_015058.1
type: Protein
SIO_000068: ncbiprotein

S000006186
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:41043-42869:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1604; Autonomously Replicating Sequence
so part of: sequence
location: 42977..43212
location: region:42977-43212:1
so has part: feature:42977-43212:1:region

S000118411
type: SGD
SIO_000068: sgd

position:42977:1
position: 42977
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:43212:1
position: 43212
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:42977-43212:1:region

YPL264C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL264C
so part of: sequence
location: complement(<43283..>44344)
location: region:43283-44344:-1
so has part: feature:43283-44344:-1:exon
subclass of: SO_0000010

855864
type: Gene
SIO_000068: ncbigene

position:43283:-1
position: 43283
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:44344:-1
position: 44344
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:43283-44344:-1:exon

YPL264C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL264C
product: uncharacterized protein
transcript id: NM_001184078.1
SIO_010081: YPL264C
subclass of: SO_0000673
so part of: YPL264C
location: complement(<43283..>44344)
location: region:43283-44344:-1
so has part: feature:43283-44344:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:43283-44344:-1:exon

YPL264C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL264C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:31945465]
note: Endoplasmic reticulum hypothetical protein; physically interacts with Hsp82p; YPL264C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MTLQRISKDYLKPNYGLILLIVSYFFNSSMVVSTKVLENDPLETSQSRINPLQILLVRMSITYCCTLVYMHWNKQSVPDIPWGPAPCRKWLILRGIMGFFGVFGMYFSLMYLSISDAVLITFMSPTLTIFLSFLLLGEPFSKLEALGSLISFSGVVLIIRPTFLFGEQTQGQQSPQDDIVETQNPKLRLIAIGVSLLGVCGLSSVYIIIRYIGNKAHAIMSVSYFSLVTTVVAALGVLLIPSMSLQLPHSWKQWGLFLNLGISGFIHQILLTMGIQRERAGRGSLMTYTQVIYAVFWDVVLFHHWPNIWTWCGMAVIVSSTIWVINMRASKQNVVATAELLSTSDFELDDLED
SIO_010081: YPL264C
subclass of: SO_0000673
so part of: YPL264C
location: complement(43283..44344)
location: region:43283-44344:-1
so has part: feature:43283-44344:-1:exon

NP_015059.1
type: Protein
SIO_000068: ncbiprotein

S000006185
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:43283-44344:-1:exon

YPL263C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KEL3
locus tag: YPL263C
so part of: sequence
location: complement(<44551..>46506)
location: region:44551-46506:-1
so has part: feature:44551-46506:-1:exon
subclass of: SO_0000010

855865
type: Gene
SIO_000068: ncbigene

position:44551:-1
position: 44551
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:46506:-1
position: 46506
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:44551-46506:-1:exon

YPL263C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KEL3
locus tag: YPL263C
product: Kel3p
transcript id: NM_001184077.1
SIO_010081: YPL263C
subclass of: SO_0000673
so part of: YPL263C
location: complement(<44551..>46506)
location: region:44551-46506:-1
so has part: feature:44551-46506:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:44551-46506:-1:exon

YPL263C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KEL3
locus tag: YPL263C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic hypothetical protein
codon start: 1
product: Kel3p
translation: MAKKNKKDKEAKKARAELKNQKNQKKQEKKFQKNKNKSLNGEEDDESDQDLDEILSSFSKKQIELEHVDITSVEKPSCRTHPLMFANPQHNKHELFIFGGEFTDPETKLTHFYNDLYSYSIKNNSWKKYVSQNAPLPRSSAAVAVHPSGIALLHGGEFSSPKQSKFYHYSDTWLFDCVERKFTKLEFGGRDSSPSARSGHRIIAWKNYFILFGGFRDLGNGQTSYLNDLWCFDISTYKWTKLETNSKPDARSGHCFIPTDNSAILMGGYCKIIAKNNKNLMKGKILNDAWKLNLTPDPKKWQWEKLKNFKNQPSPRVGYSFNLWKQNKSVAFGGVYDLQETEESLESVFYNDLYMFHLELNKWSKLRIKPQRQTNSKNSPATSKRKSNKDQEKELQDLLNSILAKSNLNDDDDDNDDNSTTGPNSIDDDEDNEDDSDLDNQEDITISNQLPHPRFNAATCVVGDSLFIYSGVWELGEKDYPINSFYSIDLNKLDGVKVYWEDLSAIEEAKRLGDRDSDEDEFEYEDDEEDEDDGEEEQDAGPLEGDEDEESESDDDKQAQMEIPDERSWLPHPKPFETLRAFYLREGANFLTWSISNNRNLKGKQLKTKSFELCEDRWWERRDQVTLEEERLEDTGGIIERDTTTKPSKRR
SIO_010081: YPL263C
subclass of: SO_0000673
so part of: YPL263C
location: complement(44551..46506)
location: region:44551-46506:-1
so has part: feature:44551-46506:-1:exon

NP_015060.1
type: Protein
SIO_000068: ncbiprotein

S000006184
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:44551-46506:-1:exon

YPL262W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUM1
locus tag: YPL262W
so part of: sequence
location: <47336..>48802
location: region:47336-48802:1
so has part: feature:47336-48802:1:exon
subclass of: SO_0000010

855866
type: Gene
SIO_000068: ncbigene

position:47336:1
position: 47336
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:48802:1
position: 48802
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:47336-48802:1:exon

YPL262W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUM1
locus tag: YPL262W
product: fumarase FUM1
transcript id: NM_001184076.1
SIO_010081: YPL262W
subclass of: SO_0000673
so part of: YPL262W
location: <47336..>48802
location: region:47336-48802:1
so has part: feature:47336-48802:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47336-48802:1:exon

YPL262W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUM1
locus tag: YPL262W
EC number: 4.2.1.2
experiment: EXISTENCE:direct assay:GO:0004333 fumarate hydratase activity [PMID:3040736]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:20231875]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:11585823]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11585823]
experiment: EXISTENCE:mutant phenotype:GO:0006099 tricarboxylic acid cycle [PMID:1587456]
experiment: EXISTENCE:mutant phenotype:GO:0006106 fumarate metabolic process [PMID:1587456]
note: Fumarase; converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria
codon start: 1
product: fumarase FUM1
translation: MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK
SIO_010081: YPL262W
subclass of: SO_0000673
so part of: YPL262W
location: 47336..48802
location: region:47336-48802:1
so has part: feature:47336-48802:1:exon

NP_015061.1
type: Protein
SIO_000068: ncbiprotein

S000006183
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47336-48802:1:exon

YPL261C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL261C
so part of: sequence
location: complement(<48996..>49304)
location: region:48996-49304:-1
so has part: feature:48996-49304:-1:exon
subclass of: SO_0000010

855868
type: Gene
SIO_000068: ncbigene

position:48996:-1
position: 48996
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:49304:-1
position: 49304
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48996-49304:-1:exon

YPL261C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL261C
product: uncharacterized protein
transcript id: NM_001348883.1
SIO_010081: YPL261C
subclass of: SO_0000673
so part of: YPL261C
location: complement(<48996..>49304)
location: region:48996-49304:-1
so has part: feature:48996-49304:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48996-49304:-1:exon

YPL261C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL261C
note: hypothetical protein; conserved among S. cerevisiae strains; YPL261C is not an essential gene; partially overlaps verified ORF YPL260W
codon start: 1
product: uncharacterized protein
translation: MLFLDSYSLLIQFQRFKNWESPRRFSSSFPLLLFVFKPIFAAKLLKEICSSGVLSYSLSFLKIPLSVMRVILGPLPDDKKLKNDAKYSFMNYFIITCIGIIM
SIO_010081: YPL261C
subclass of: SO_0000673
so part of: YPL261C
location: complement(48996..49304)
location: region:48996-49304:-1
so has part: feature:48996-49304:-1:exon

NP_001335821.1
type: Protein
SIO_000068: ncbiprotein

S000006182
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48996-49304:-1:exon

YPL260W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CUB1
locus tag: YPL260W
so part of: sequence
location: <49303..>50958
location: region:49303-50958:1
so has part: feature:49303-50958:1:exon
subclass of: SO_0000010

855867
type: Gene
SIO_000068: ncbigene

position:49303:1
position: 49303
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:50958:1
position: 50958
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:49303-50958:1:exon

YPL260W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CUB1
locus tag: YPL260W
product: Cub1p
transcript id: NM_001184074.1
SIO_010081: YPL260W
subclass of: SO_0000673
so part of: YPL260W
location: <49303..>50958
location: region:49303-50958:1
so has part: feature:49303-50958:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:49303-50958:1:exon

YPL260W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CUB1
locus tag: YPL260W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Conserved fungal gene linked to DNA repair and proteasome function; putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene; protein abundance increases in response to DNA replication stress
codon start: 1
product: Cub1p
translation: MFASAGQQHPQIVPKEEESILNYLLEVRSSLAKLKQNRTQYLNSKDVQTTYQHVLTKVRELDDIRKNSHETPAKSAATLIHSTELHNRVDSVLDDVFQLLSLCFLTVGLKNSAPATYASLSTVESLLEHLNESNVFTHHDLSPIKERLEEISKIVEQKNSSPAYDEDGNDDRLREIDNERKKNKIEEDLLLRAKLKHCKDEYDILEGKLEEIDPSLSTVMEKLFRIRRGLLSLVASAKKTMSKSDINTNSLLQEQNDLQTNNESLTDDKHLVSQEYVHEKLSVLKNELSELESNRDDSGKFKSLESHQVAEKGQSVLNGLLDDCHDLVNDLSHQKNGGLTLDPYLQPIYEQLIDIKTTLENLMITRRWTLRETDLFSYQKKLNEIDNKRINGKFPTKSQDSKGQSILLYLLRRCYAIIYKLLESSEPVSEALQPIHNQLSTVRRCLLELKRMGGVNNERELYPYQMKLASLDNLRTEGIFYDSDGNIPEGQGILNALLAECFDILHELKVEAEEKAQNSTSSDGSDDDDNGESGIDSNSNDSEPESEYQQE
SIO_010081: YPL260W
subclass of: SO_0000673
so part of: YPL260W
location: 49303..50958
location: region:49303-50958:1
so has part: feature:49303-50958:1:exon

NP_015063.1
type: Protein
SIO_000068: ncbiprotein

S000006181
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:49303-50958:1:exon

YPL259C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAP54
gene: APM1
locus tag: YPL259C
gene synonym: YAP54
so part of: sequence
location: complement(<51244..>52671)
location: region:51244-52671:-1
so has part: feature:51244-52671:-1:exon
subclass of: SO_0000010

855869
type: Gene
SIO_000068: ncbigene

position:51244:-1
position: 51244
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:52671:-1
position: 52671
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:51244-52671:-1:exon

YPL259C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAP54
gene: APM1
locus tag: YPL259C
gene synonym: YAP54
product: Apm1p
transcript id: NM_001184073.1
SIO_010081: YPL259C
subclass of: SO_0000673
so part of: YPL259C
location: complement(<51244..>52671)
location: region:51244-52671:-1
so has part: feature:51244-52671:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:51244-52671:-1:exon

YPL259C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAP54
gene: APM1
locus tag: YPL259C
gene synonym: YAP54
experiment: EXISTENCE:direct assay:GO:0030121 AP-1 adaptor complex [PMID:10564262]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:17003107]
note: Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex
codon start: 1
product: Apm1p
translation: MASAVYFCDHNGKPLLSRRYRDDIPLSAIDKFPILLSDLEEQSNLIPPCLNHNGLEYLFIQHNDLYVVAIVTSLSANAAAIFTFLHKLVEVLSDYLKTVEEESIRDNFVIIYELLDEVMDYGIPQITETKMLKQYITQKSFKLVKSAKKKRNATRPPVALTNSVSWRPEGITHKKNEAFLDIVESINMLMTQKGQVLRSEIIGDVKVNSKLSGMPDLKLGINDKGIFSKYLDDDTNIPSASATTSDNNTETDKKPSITSSSATNKKKVNIELEDLKFHQCVRLSKFENEKIITFIPPDGKFDLMNYRLSTTIKPLIWCDVNVQVHSNSRIEIHCKAKAQIKRKSTATNVEILIPVPDDADTPTFKYSHGSLKYVPEKSAILWKIRSFPGGKEYSMSAELGLPSISNNEDGNRTMPKSNAEILKGPVQIKFQIPYFTTSGIQVRYLKINEPKLQYKSYPWVRYITQSGDDYTIRLT
SIO_010081: YPL259C
subclass of: SO_0000673
so part of: YPL259C
location: complement(51244..52671)
location: region:51244-52671:-1
so has part: feature:51244-52671:-1:exon

NP_015064.1
type: Protein
SIO_000068: ncbiprotein

S000006180
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:51244-52671:-1:exon

YPL258C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THI21
locus tag: YPL258C
so part of: sequence
location: complement(<53498..>55153)
location: region:53498-55153:-1
so has part: feature:53498-55153:-1:exon
subclass of: SO_0000010

855870
type: Gene
SIO_000068: ncbigene

position:53498:-1
position: 53498
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:55153:-1
position: 55153
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:53498-55153:-1:exon

YPL258C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THI21
locus tag: YPL258C
product: bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
transcript id: NM_001184072.1
SIO_010081: YPL258C
subclass of: SO_0000673
so part of: YPL258C
location: complement(<53498..>55153)
location: region:53498-55153:-1
so has part: feature:53498-55153:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:53498-55153:-1:exon

YPL258C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THI21
locus tag: YPL258C
EC number: 2.7.1.49
EC number: 2.7.4.7
experiment: EXISTENCE:direct assay:GO:0008902 hydroxymethylpyrimidine kinase activity [PMID:15614489]
experiment: EXISTENCE:direct assay:GO:0008972 phosphomethylpyrimidine kinase activity [PMID:15614489]
experiment: EXISTENCE:genetic interaction:GO:0008902 hydroxymethylpyrimidine kinase activity [PMID:15614489]
experiment: EXISTENCE:genetic interaction:GO:0008972 phosphomethylpyrimidine kinase activity [PMID:10383756|PMID:15614489]
experiment: EXISTENCE:genetic interaction:GO:0009228 thiamine biosynthetic process [PMID:10383756]
note: Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p
codon start: 1
product: bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
translation: MTYSTVNINTPPPYLALASNEKLPTVLSIAGTDPSGGAGVEADVKTITAHRCYAMTCITALNAQTPVKVYSINNTPKEVVSQILDANLQDMKCDVIKTGMLTTAAIEVLHEKLLQLGENRPKLVVDPVLVATSGSSLAGKDIASLITEKIAPFADILTPNIPECFKLLGEDREISKLRDIFEVAKDLAKITKCSNILVKGGHIPWNDEEGKYITDVLYLGAEQRFITFKGNFVNTTHTHGTGCTLASAIASNLARGYSLPQSVYGGIEYVQNAVAIGCDVTKETVKDNGPINHVYAIEIPLEKMLSDECFTASDAVHKKPVKSSLNKIPGGSFYKYLINHPKVKPHWDSYVNHDFVRKVADGSLEPKKFQFFIEQDYLYLVNYARISCIAGSKSPCLEDLEKELVIVECVRNGLCQHERRLREEFGIKDPDYLQKIQRGPALRAYCRYFNDVSRRGNWQELVIALNPCLMGYVHALTKIKDEVTAAEGSVYREWCETYSSSWCHEAMLEGEKLLNHILETYPPEKLDTLVTIYAEVCELEANFWTAALEYE
SIO_010081: YPL258C
subclass of: SO_0000673
so part of: YPL258C
location: complement(53498..55153)
location: region:53498-55153:-1
so has part: feature:53498-55153:-1:exon

NP_015065.1
type: Protein
SIO_000068: ncbiprotein

S000006179
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:53498-55153:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(55657..55858)
location: region:55657-55858:-1
so has part: feature:55657-55858:-1:region

S000007184
type: SGD
SIO_000068: sgd

position:55657:-1
position: 55657
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:55858:-1
position: 55858
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:55657-55858:-1:region

YNCP0001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0001C
so part of: sequence
location: complement(56169..56274)
location: region:56169-56274:-1
so has part: feature:56169-56274:-1:exon
subclass of: SO_0000663

855815
type: Gene
SIO_000068: ncbigene

position:56169:-1
position: 56169
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:56274:-1
position: 56274
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56169-56274:-1:exon

YNCP0001C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0001C
product: tRNA-Trp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tryptophan tRNA (tRNA-Trp), predicted by tRNAscan-SE analysis
SIO_010081: YNCP0001C
subclass of: SO_0000673
so part of: YNCP0001C
location: complement(join(56169..56204,56239..56274))
location: region:56169-56274:-1
so has part: feature:56239-56274:-1:exon
so has part: feature:56169-56204:-1:exon

S000006776
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56239-56274:-1:exon

position:56239:-1
position: 56239
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:56169-56204:-1:exon

position:56204:-1
position: 56204
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 56290..56358
location: region:56290-56358:1
so has part: feature:56290-56358:1:region

S000007198
type: SGD
SIO_000068: sgd

position:56290:1
position: 56290
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:56358:1
position: 56358
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56290-56358:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 56409..56451
location: region:56409-56451:1
so has part: feature:56409-56451:1:region

S000007189
type: SGD
SIO_000068: sgd

position:56409:1
position: 56409
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:56451:1
position: 56451
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56409-56451:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YPLWTy1-1; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YPLWTy1-1
so part of: sequence
location: 56452..62375
location: region:56452-62375:1
so has part: feature:56452-62375:1:region

S000007199
type: SGD
SIO_000068: sgd

position:56452:1
position: 56452
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:62375:1
position: 62375
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56452-62375:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 56452..56788
location: region:56452-56788:1
so has part: feature:56452-56788:1:region

S000007190
type: SGD
SIO_000068: sgd

position:56788:1
position: 56788
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56452-56788:1:region

YPL257W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL257W-B
so part of: sequence
location: <56748..>62016
location: region:56748-62016:1
so has part: feature:56748-62016:1:exon
subclass of: SO_0000010

855817
type: Gene
SIO_000068: ncbigene

position:56748:1
position: 56748
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62016:1
position: 62016
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56748-62016:1:exon

YPL257W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL257W-B
product: gag-pol fusion protein
transcript id: NM_001184392.2
SIO_010081: YPL257W-B
subclass of: SO_0000673
so part of: YPL257W-B
location: <56748..>62016
location: region:56748-62016:1
so has part: feature:56748-62016:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:56748-62016:1:exon

YPL257W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL257W-B
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YPL257W-B
subclass of: SO_0000673
so part of: YPL257W-B
location: join(56748..58052,58054..62016)
location: region:56748-62016:1
so has part: feature:56748-58052:1:exon
so has part: feature:58054-62016:1:exon

NP_058189.1
type: Protein
SIO_000068: ncbiprotein

S000007358
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56748-58052:1:exon

position:58052:1
position: 58052
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:58054-62016:1:exon

position:58054:1
position: 58054
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL257W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL257W-A
so part of: sequence
location: <56748..>58070
location: region:56748-58070:1
so has part: feature:56748-58070:1:exon
subclass of: SO_0000010

855816
type: Gene
SIO_000068: ncbigene

position:58070:1
position: 58070
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56748-58070:1:exon

YPL257W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL257W-A
product: gag protein
transcript id: NM_001184391.1
SIO_010081: YPL257W-A
subclass of: SO_0000673
so part of: YPL257W-A
location: <56748..>58070
location: region:56748-58070:1
so has part: feature:56748-58070:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:56748-58070:1:exon

YPL257W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL257W-A
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY
SIO_010081: YPL257W-A
subclass of: SO_0000673
so part of: YPL257W-A
location: 56748..58070
location: region:56748-58070:1
so has part: feature:56748-58070:1:exon

NP_058190.1
type: Protein
SIO_000068: ncbiprotein

S000007357
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56748-58070:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 62039..62375
location: region:62039-62375:1
so has part: feature:62039-62375:1:region

S000007191
type: SGD
SIO_000068: sgd

position:62039:1
position: 62039
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:62039-62375:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 62389..62720
location: region:62389-62720:1
so has part: feature:62389-62720:1:region

S000007192
type: SGD
SIO_000068: sgd

position:62389:1
position: 62389
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:62720:1
position: 62720
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:62389-62720:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 62724..63006
location: region:62724-63006:1
so has part: feature:62724-63006:1:region

S000007193
type: SGD
SIO_000068: sgd

position:62724:1
position: 62724
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:63006:1
position: 63006
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:62724-63006:1:region

YPL257W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL257W
so part of: sequence
location: <63279..>63860
location: region:63279-63860:1
so has part: feature:63279-63860:1:exon
subclass of: SO_0000010

855818
type: Gene
SIO_000068: ncbigene

position:63279:1
position: 63279
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:63860:1
position: 63860
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63279-63860:1:exon

YPL257W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL257W
product: uncharacterized protein
transcript id: NM_001184071.1
SIO_010081: YPL257W
subclass of: SO_0000673
so part of: YPL257W
location: <63279..>63860
location: region:63279-63860:1
so has part: feature:63279-63860:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63279-63860:1:exon

YPL257W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL257W
note: hypothetical protein; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MTAHANERISDVSPSARGSSSESKYDKLCRVLFFIAITKSSFTPEHILYKHSIFTDKPILADIVTFMYAAFVSIGWFLIWGERAYRTQEMGQPPMYSNINYHLLSFKKRHPKKFTCALWLVFFLAYTVLTVLIWLVQLIFRKGNVFQMLLQLIILDIAIALVNVAIAFTFEIYLSQKAAIEIRDEGLNNLDTA
SIO_010081: YPL257W
subclass of: SO_0000673
so part of: YPL257W
location: 63279..63860
location: region:63279-63860:1
so has part: feature:63279-63860:1:exon

NP_015066.1
type: Protein
SIO_000068: ncbiprotein

S000006178
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63279-63860:1:exon

YPL256C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CLN2
locus tag: YPL256C
so part of: sequence
location: complement(<64977..>66614)
location: region:64977-66614:-1
so has part: feature:64977-66614:-1:exon
subclass of: SO_0000010

855819
type: Gene
SIO_000068: ncbigene

position:64977:-1
position: 64977
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:66614:-1
position: 66614
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:64977-66614:-1:exon

YPL256C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CLN2
locus tag: YPL256C
product: cyclin CLN2
transcript id: NM_001184070.1
SIO_010081: YPL256C
subclass of: SO_0000673
so part of: YPL256C
location: complement(<64977..>66614)
location: region:64977-66614:-1
so has part: feature:64977-66614:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:64977-66614:-1:exon

YPL256C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CLN2
locus tag: YPL256C
experiment: EXISTENCE:direct assay:GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:7862657|PMID:8387915|PMID:10409718]
experiment: EXISTENCE:direct assay:GO:0000307 cyclin-dependent protein kinase holoenzyme complex [PMID:2142620]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10611233|PMID:11080155|PMID:11792824]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11509671|PMID:10611233|PMID:11080155|PMID:11792824]
experiment: EXISTENCE:direct assay:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:10409718|PMID:7862657|PMID:8387915]
experiment: EXISTENCE:genetic interaction:GO:0000321 re-entry into mitotic cell cycle after pheromone arrest [PMID:9927449]
experiment: EXISTENCE:genetic interaction:GO:0007089 traversing start control point of mitotic cell cycle [PMID:2574633|PMID:2147225]
experiment: EXISTENCE:mutant phenotype:GO:0005737 cytoplasm [PMID:11509671]
experiment: EXISTENCE:mutant phenotype:GO:0007089 traversing start control point of mitotic cell cycle [PMID:2569741]
note: G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p); CLN2 has a paralog, CLN1, that arose from the whole genome duplication; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1
codon start: 1
product: cyclin CLN2
translation: MASAEPRPRMGLVINAKPDYYPIELSNAELLSHFEMLQEYHQEISTNVIAQSCKFKPNPKLIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIFFHSVRLYDRYCSKRIVLRDQAKLVVATCLWLAAKTWGGCNHIINNVVIPTGGRFYGPNPRARIPRLSELVHYCGDGQVFDESMFLQMERHILDTLNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDKQCSEKRQSQLSQDSDATVDERPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELFEVSHGIFSIINQFTNQDHGPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVLPFINQVKEYHLDLQRKLQIASNLNISRKLTISTPSCSFENSNSTSIPSPASSSQSHTPMRNMSSLSDNSVFSRNMEQSSPITPSMYQFGQQQSNSICGSTVSVNSLVNTNNKQRIYEQITGPNSNNATNDYIDLLNLNESNKENQNPATAHYLNGGPPKTSFINHGMFPSPTGTINSGKSSSASSLISFGMGNTQVI
SIO_010081: YPL256C
subclass of: SO_0000673
so part of: YPL256C
location: complement(64977..66614)
location: region:64977-66614:-1
so has part: feature:64977-66614:-1:exon

NP_015067.1
type: Protein
SIO_000068: ncbiprotein

S000006177
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:64977-66614:-1:exon

YPL255W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BBP1
locus tag: YPL255W
so part of: sequence
location: <67725..>68882
location: region:67725-68882:1
so has part: feature:67725-68882:1:exon
subclass of: SO_0000010

855820
type: Gene
SIO_000068: ncbigene

position:67725:1
position: 67725
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:68882:1
position: 68882
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:67725-68882:1:exon

YPL255W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BBP1
locus tag: YPL255W
product: Bbp1p
transcript id: NM_001184069.1
SIO_010081: YPL255W
subclass of: SO_0000673
so part of: YPL255W
location: <67725..>68882
location: region:67725-68882:1
so has part: feature:67725-68882:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:67725-68882:1:exon

YPL255W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BBP1
locus tag: YPL255W
experiment: EXISTENCE:direct assay:GO:0005198 structural molecule activity [PMID:20139001]
experiment: EXISTENCE:direct assay:GO:0005823 central plaque of spindle pole body [PMID:10654940]
experiment: EXISTENCE:genetic interaction:GO:0030474 spindle pole body duplication [PMID:10654940]
experiment: EXISTENCE:mutant phenotype:GO:0030474 spindle pole body duplication [PMID:10654940]
experiment: EXISTENCE:mutant phenotype:GO:0071988 protein localization to spindle pole body [PMID:14767068|PMID:11952896]
note: Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
codon start: 1
product: Bbp1p
translation: MNQEDNTGGGGIFGLFKWTKDALFGTDISPSMKYKDQEERRDRSRYAQDDTNFSMKFGNDSNRRSTNLSRSNSWSGLDSTLHRKYELLPEYNENGFNSIVNGDHHSKERIRSLRSPAPIVPREPLRNEPTDTFGHRLHTKRRTINELSNSQIPFIPPQEDDPLLSKLFNKDGVNEVRRSPYKLSVKDIPGKFPSPLTKRDEIDNYYVRDEDACHKNREYKKAYFDLFAQMDLNSRDLEDLCEDVREQREQFHRNEQTYKQAYEEMRAELVNELKKSKTLFENYYSLGQKYKSLKKVLDQTISHEAELATSRERLYQEEDLKNFEIQTLKQRLSDLELKYTNLQIEKDMQRDNYESEIHDLLLQLSLRNNERKDTSAGSNIFSTGQ
SIO_010081: YPL255W
subclass of: SO_0000673
so part of: YPL255W
location: 67725..68882
location: region:67725-68882:1
so has part: feature:67725-68882:1:exon

NP_015068.1
type: Protein
SIO_000068: ncbiprotein

S000006176
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:67725-68882:1:exon

YPL254W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ADA1
alternative label: GAN1
alternative label: SRM12
alternative label: SUP110
gene: HFI1
locus tag: YPL254W
gene synonym: ADA1; GAN1; SRM12; SUP110
so part of: sequence
location: <69485..>70951
location: region:69485-70951:1
so has part: feature:69485-70951:1:exon
subclass of: SO_0000010

855821
type: Gene
SIO_000068: ncbigene

position:69485:1
position: 69485
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:70951:1
position: 70951
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:69485-70951:1:exon

YPL254W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ADA1
alternative label: GAN1
alternative label: SRM12
alternative label: SUP110
gene: HFI1
locus tag: YPL254W
gene synonym: ADA1; GAN1; SRM12; SUP110
product: Hfi1p
transcript id: NM_001184068.1
SIO_010081: YPL254W
subclass of: SO_0000673
so part of: YPL254W
location: <69485..>70951
location: region:69485-70951:1
so has part: feature:69485-70951:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:69485-70951:1:exon

YPL254W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ADA1
alternative label: GAN1
alternative label: SRM12
alternative label: SUP110
gene: HFI1
locus tag: YPL254W
gene synonym: ADA1; GAN1; SRM12; SUP110
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex [PMID:9154821]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0046695 SLIK (SAGA-like) complex [PMID:12446794]
experiment: EXISTENCE:mutant phenotype:GO:0003712 transcription coregulator activity [PMID:9154821]
experiment: EXISTENCE:mutant phenotype:GO:0003713 transcription coactivator activity [PMID:10048020]
experiment: EXISTENCE:mutant phenotype:GO:0006366 transcription by RNA polymerase II [PMID:9154821]
note: Adaptor protein required for structural integrity of the SAGA complex; a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions
codon start: 1
product: Hfi1p
translation: MSAIQSPAPKPLQPTYPAASPASTNAYMKPGLIGSPAVSNHTEPNNGNNETAEPQGPNQRIDLGAMIEELTSLLGKESWTKYAQIISLFILGKLSRKELSNELELVFSPSAASLEKSNTNHHHSLVRLHNQLLLGIFANSLRENPLGRNGNESSWGFGNGSNNPNNKLKRINKHNSQIEVYKKIVMSLPLNDRNRLKMITKEAGKRGFIFCSVFQARLNNIPKIPIVTNPESLKRVKSNNLKTPLEWSQDIMNGFNVPLASESHSLPDTDSFYLRMVGIAREHGLVGTVDARCVELISLALDQYLKNIIEFTIDTVRYRRKKYSDYYDLNESGLYKSVSEMAADKRDAKIKQLDDDKNEDECADEAKSINNGNNSSKDDIGDISMSSITKAGEAVNEELHENRTISLTNEDIYDSLSIFPNLVEPSGSYYALTNLGLVNDDELVDMKSNIDDLPDFLNEKPTFTPLDERNVGTRHELNWLIKGILTED
SIO_010081: YPL254W
subclass of: SO_0000673
so part of: YPL254W
location: 69485..70951
location: region:69485-70951:1
so has part: feature:69485-70951:1:exon

NP_015069.1
type: Protein
SIO_000068: ncbiprotein

S000006175
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:69485-70951:1:exon

YPL253C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VIK1
locus tag: YPL253C
so part of: sequence
location: complement(<71063..>73006)
location: region:71063-73006:-1
so has part: feature:71063-73006:-1:exon
subclass of: SO_0000010

855822
type: Gene
SIO_000068: ncbigene

position:71063:-1
position: 71063
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73006:-1
position: 73006
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:71063-73006:-1:exon

YPL253C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VIK1
locus tag: YPL253C
product: Vik1p
transcript id: NM_001184067.1
SIO_010081: YPL253C
subclass of: SO_0000673
so part of: YPL253C
location: complement(<71063..>73006)
location: region:71063-73006:-1
so has part: feature:71063-73006:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:71063-73006:-1:exon

YPL253C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VIK1
locus tag: YPL253C
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:10087265|PMID:11729143]
experiment: EXISTENCE:direct assay:GO:0005871 kinesin complex [PMID:10087265]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:22734002]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:14742714]
experiment: EXISTENCE:mutant phenotype:GO:0007017 microtubule-based process [PMID:10087265]
experiment: EXISTENCE:mutant phenotype:GO:0007020 microtubule nucleation [PMID:33752231]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:14742714]
experiment: EXISTENCE:physical interaction:GO:0007017 microtubule-based process [PMID:10087265]
note: Protein that forms a kinesin-14 heterodimeric motor with Kar3p; localizes Kar3p at mitotic spindle poles; has a structure similar to a kinesin motor domain but lacks an ATP-binding site and is catalytically inactive; binds microtubules; required for sister chromatid cohesion; VIK1 has a paralog, CIK1, that arose from the whole genome duplication
codon start: 1
product: Vik1p
translation: MASQQNKHAFLSKNRIFHNPDNVSSSKSRNLMDITNTTNTMNGSRPSSMKSSLALPPVKDSFPSVSRSASLNINMSKIKDLKDRQDKIRFQRHTLRTQLIECEREIKTIKFRDLNKSRFELYKKKSKQAKYLKQVRDLTQNLNSKDGERADLIKKNKSALATLQAELDQNLILKRQESQELYNNKLIFWENELQIMENVEPDHEITEEISQLKKTLQELNINWANLQKQNLERQVNHESQLRKDFIAFKEAKLKSMENLTNKHRELLDQIATLQSESEKLHKEIMDIDRQAEYSEQNISEINENIKQLELANNPLISKSLQNSQDLEHLQNQMENLKEMASKQEKFYNDTYNTVEKELLRSRRLENSIIEQKGTMRCYAYVMEQNLPENLLFDYENGVITQGLSEHVYKFNRVIPHLKVSEDKFFTQEYSVYHDMCLNQKKNFNLISLSTTPHGSLRESLIKFLAEKDTIYQKQYVITLQFVFLSDDEFSQDMLLDYSHNDKDSIKLKFEKHSISLDSKLVIIENGLEDLPLNFSCDEHPNLPHSGMGIIKVQFFPRDSKSDGNNDPVPVDFYFIELNNLKSIEQFDKSIFKKESCETPIALVLKKLISDTKSFFLLNLNDSKNVNKLLTISEEVQTQLCKRKKKLT
SIO_010081: YPL253C
subclass of: SO_0000673
so part of: YPL253C
location: complement(71063..73006)
location: region:71063-73006:-1
so has part: feature:71063-73006:-1:exon

NP_015070.1
type: Protein
SIO_000068: ncbiprotein

S000006174
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:71063-73006:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1605; Autonomously Replicating Sequence
so part of: sequence
location: 73032..73227
location: region:73032-73227:1
so has part: feature:73032-73227:1:region

S000118412
type: SGD
SIO_000068: sgd

position:73032:1
position: 73032
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:73227:1
position: 73227
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73032-73227:1:region

YPL252C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAH1
locus tag: YPL252C
so part of: sequence
location: complement(<73363..>73881)
location: region:73363-73881:-1
so has part: feature:73363-73881:-1:exon
subclass of: SO_0000010

855824
type: Gene
SIO_000068: ncbigene

position:73363:-1
position: 73363
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73881:-1
position: 73881
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73363-73881:-1:exon

YPL252C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAH1
locus tag: YPL252C
product: adrenodoxin
transcript id: NM_001184066.1
SIO_010081: YPL252C
subclass of: SO_0000673
so part of: YPL252C
location: complement(<73363..>73881)
location: region:73363-73881:-1
so has part: feature:73363-73881:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:73363-73881:-1:exon

YPL252C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAH1
locus tag: YPL252C
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:10375636]
experiment: EXISTENCE:genetic interaction:GO:0006784 heme A biosynthetic process [PMID:11788607]
experiment: EXISTENCE:genetic interaction:GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [PMID:11788607]
experiment: EXISTENCE:mutant phenotype:GO:0006744 ubiquinone biosynthetic process [PMID:21944752|PMID:20534343]
experiment: EXISTENCE:mutant phenotype:GO:0006784 heme A biosynthetic process [PMID:11788607]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:12970193]
experiment: EXISTENCE:mutant phenotype:GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [PMID:11788607]
note: Ferredoxin of the mitochondrial matrix; required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; human homolog FDX1L can complement yeast by allowing growth during down-regulation of yeast YAH1
codon start: 1
product: adrenodoxin
translation: MLKIVTRAGHTARISNIAAHLLRTSPSLLTRTTTTTRFLPFSTSSFLNHGHLKKPKPGEELKITFILKDGSQKTYEVCEGETILDIAQGHNLDMEGACGGSCACSTCHVIVDPDYYDALPEPEDDENDMLDLAYGLTETSRLGCQIKMSKDIDGIRVALPQMTRNVNNNDFS
SIO_010081: YPL252C
subclass of: SO_0000673
so part of: YPL252C
location: complement(73363..73881)
location: region:73363-73881:-1
so has part: feature:73363-73881:-1:exon

NP_015071.1
type: Protein
SIO_000068: ncbiprotein

S000006173
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:73363-73881:-1:exon

YPL250C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ICY2
gene: ATG41
locus tag: YPL250C
gene synonym: ICY2
so part of: sequence
location: complement(<74309..>74719)
location: region:74309-74719:-1
so has part: feature:74309-74719:-1:exon
subclass of: SO_0000010

855825
type: Gene
SIO_000068: ncbigene

position:74309:-1
position: 74309
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:74719:-1
position: 74719
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74309-74719:-1:exon

YPL250C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ICY2
gene: ATG41
locus tag: YPL250C
gene synonym: ICY2
product: Atg41p
transcript id: NM_001184064.1
SIO_010081: YPL250C
subclass of: SO_0000673
so part of: YPL250C
location: complement(<74309..>74719)
location: region:74309-74719:-1
so has part: feature:74309-74719:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:74309-74719:-1:exon

YPL250C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ICY2
gene: ATG41
locus tag: YPL250C
gene synonym: ICY2
experiment: EXISTENCE:mutant phenotype:GO:0000045 autophagosome assembly [PMID:26565778]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:26565778]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:26565778]
note: hypothetical protein; required for selective and nonselective autophagy, and mitophagy; regulates the rate of autophagosome formation; interacts with Atg9p, and has a similar peri-mitochondrial localization; elevated Gcn4p-dependent expression under autophagy-inducing conditions; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate; ATG41 has a paralog, ICY1, that arose from the whole genome duplication
codon start: 1
product: Atg41p
translation: MSSVESSPISRYEDEVFPLSFSNVAFEPPMLSHSPDRSTYADDFSQSYQQELLTFPLSYPIVDESECTHTKDKTDSNIITSTEDDCMFDMEFNGNAASAVAAASKESNSASGFAFASNDAFANVAQQNYRLWLSSV
SIO_010081: YPL250C
subclass of: SO_0000673
so part of: YPL250C
location: complement(74309..74719)
location: region:74309-74719:-1
so has part: feature:74309-74719:-1:exon

NP_015073.1
type: Protein
SIO_000068: ncbiprotein

S000006171
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:74309-74719:-1:exon

YPL249C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL36B
locus tag: YPL249C-A
so part of: sequence
location: complement(<75699..>76239)
location: region:75699-76239:-1
so has part: feature:75699-76239:-1:exon
subclass of: SO_0000010

855826
type: Gene
SIO_000068: ncbigene

position:75699:-1
position: 75699
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:76239:-1
position: 76239
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:75699-76239:-1:exon

YPL249C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL36B
locus tag: YPL249C-A
product: ribosomal 60S subunit protein L36B
transcript id: NM_001184312.1
SIO_010081: YPL249C-A
subclass of: SO_0000673
so part of: YPL249C-A
location: complement(join(<75699..75985,76224..>76239))
location: region:75699-76239:-1
so has part: feature:76224-76239:-1:exon
so has part: feature:75699-75985:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76224-76239:-1:exon

position:76224:-1
position: 76224
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:75699-75985:-1:exon

position:75985:-1
position: 75985
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL249C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL36B
locus tag: YPL249C-A
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:6337137]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
note: Ribosomal 60S subunit protein L36B; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L36, no bacterial homolog; RPL36B has a paralog, RPL36A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L36B
translation: MAVKTGIAIGLNKGKKVTQMTPAPKISYKKGAASNRTKFVRSLVREIAGLSPYERRLIDLIRNSGEKRARKVAKKRLGSFTRAKAKVEEMNNIIAASRRH
SIO_010081: YPL249C-A
subclass of: SO_0000673
so part of: YPL249C-A
location: complement(join(75699..75985,76224..76239))
location: region:75699-76239:-1
so has part: feature:76224-76239:-1:exon
so has part: feature:75699-75985:-1:exon

NP_015074.1
type: Protein
SIO_000068: ncbiprotein

S000006438
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76224-76239:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:75699-75985:-1:exon

YPL249C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GYP5
locus tag: YPL249C
so part of: sequence
location: complement(<76669..>79353)
location: region:76669-79353:-1
so has part: feature:76669-79353:-1:exon
subclass of: SO_0000010

855827
type: Gene
SIO_000068: ncbigene

position:76669:-1
position: 76669
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:79353:-1
position: 79353
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76669-79353:-1:exon

YPL249C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GYP5
locus tag: YPL249C
product: GTPase-activating protein GYP5
transcript id: NM_001184063.1
SIO_010081: YPL249C
subclass of: SO_0000673
so part of: YPL249C
location: complement(<76669..>79353)
location: region:76669-79353:-1
so has part: feature:76669-79353:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76669-79353:-1:exon

YPL249C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GYP5
locus tag: YPL249C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:15331637]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005798 Golgi-associated vesicle [PMID:15331637]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:12189143|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:15331637]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:15331637|PMID:22842922|PMID:32015451]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:15331637|PMID:22842922|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:35134079]
experiment: EXISTENCE:mutant phenotype:GO:0005096 GTPase activator activity [PMID:12189143|PMID:15802519]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:15802519]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:12189143]
note: GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication
codon start: 1
product: GTPase-activating protein GYP5
translation: MSSDKSIEKNTDTIASEVHEGDNHSNNLGSMEEEIKSTPSDQYEEIAIIPTEPLHSDKELNDKQQSLGHEAPTNVSREEPIGISGDEDTQITEQNVNEQRQETREPSSEIDLNEPLDVEKDVTTDVQAPNGLNIEKEYDAVKENEKVYADTKEVVSSPENREVTGKNSGGEKSSSSKFLDDESGTTTAANANDISISSEVTPERSSENDNNQIHITNEVAAGINLNENKEQKAAIEDGPVTAENLSSETARKVPPIPTQIINEKGDNSSENEVSAIPTTSSPPLPPRQNVATSTSPKLPPRGKQREQPPKTKNAVPPPLEEEMKSEKFRKNFEETKRNSYHHVPLTGSKTAQLESTAEINLIASRYRKTSHHLNKEGEETRESLQEGQSFLKSTFTSFLENLSEYNEVENVNEEDREMFKIDWSFWTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANSKSREMEDIYETLLDTECLHEATIRRDLRRTKFVAEDKMESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEETLVKLRFDELLDFLKDELFNYYLMGNQDDASVVQMGLSNGNSFKGNDDGTFSYNVDLFVHDAMTGVYITPLTLRRYRGEYVEIHEKEQKKEDHYESLRIQNHQLQREAQKLEHDYSILNKENISAANELIQNRLNMEMLLDEKNDLINTITDIKSQIEEEIRKQNLPNPDASLPKADLREDLERTISRNNEVMRENGQLEERITELQAEIDELININKEQVSTASLLERDSKAKGRKGWTGFKKVFK
SIO_010081: YPL249C
subclass of: SO_0000673
so part of: YPL249C
location: complement(76669..79353)
location: region:76669-79353:-1
so has part: feature:76669-79353:-1:exon

NP_015075.1
type: Protein
SIO_000068: ncbiprotein

S000006170
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76669-79353:-1:exon

YNCP0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0002W
so part of: sequence
location: 79562..82648
location: region:79562-82648:1
so has part: feature:79562-82648:1:exon
subclass of: SO_0000011

65052918
type: Gene
SIO_000068: ncbigene

position:79562:1
position: 79562
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:82648:1
position: 82648
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:79562-82648:1:exon

YNCP0002W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: antisense_RNA
locus tag: YNCP0002W
product: GAL4 lncRNA
note: Antisense to GAL4/YPL248C; influences expression of GAL4 mRNA
transcript id: NR_172478.1
SIO_010081: YNCP0002W
subclass of: SO_0000673
so part of: YNCP0002W
location: 79562..82648
location: region:79562-82648:1
so has part: feature:79562-82648:1:exon

S000303815
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:79562-82648:1:exon

YPL248C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GAL81
gene: GAL4
locus tag: YPL248C
gene synonym: GAL81
so part of: sequence
location: complement(<79711..>82356)
location: region:79711-82356:-1
so has part: feature:79711-82356:-1:exon
subclass of: SO_0000010

855828
type: Gene
SIO_000068: ncbigene

position:79711:-1
position: 79711
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:82356:-1
position: 82356
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:79711-82356:-1:exon

YPL248C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GAL81
gene: GAL4
locus tag: YPL248C
gene synonym: GAL81
product: galactose-responsive transcription factor GAL4
transcript id: NM_001184062.1
SIO_010081: YPL248C
subclass of: SO_0000673
so part of: YPL248C
location: complement(<79711..>82356)
location: region:79711-82356:-1
so has part: feature:79711-82356:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:79711-82356:-1:exon

YPL248C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GAL81
gene: GAL4
locus tag: YPL248C
gene synonym: GAL81
experiment: EXISTENCE:direct assay:GO:0000435 positive regulation of transcription from RNA polymerase II promoter by galactose [PMID:3886158]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:3886158]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:3080805]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:6091123]
experiment: EXISTENCE:direct assay:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:14871930]
experiment: EXISTENCE:genetic interaction:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:14871930]
experiment: EXISTENCE:mutant phenotype:GO:0000435 positive regulation of transcription from RNA polymerase II promoter by galactose [PMID:6350827]
experiment: EXISTENCE:mutant phenotype:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:14871930]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:3080805]
experiment: EXISTENCE:mutant phenotype:GO:0006012 galactose metabolic process [PMID:6350827]
experiment: EXISTENCE:physical interaction:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:14871930]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:14871930]
note: DNA-binding transcription factor required for activating GAL genes; responds to galactose; repressed by Gal80p and activated by Gal3p
codon start: 1
product: galactose-responsive transcription factor GAL4
translation: MKLLSSIEQACDICRLKKLKCSKEKPKCAKCLKNNWECRYSPKTKRSPLTRAHLTEVESRLERLEQLFLLIFPREDLDMILKMDSLQDIKALLTGLFVQDNVNKDAVTDRLASVETDMPLTLRQHRISATSSSEESSNKGQRQLTVSIDSAAHHDNSTIPLDFMPRDALHGFDWSEEDDMSDGLPFLKTDPNNNGFFGDGSLLCILRSIGFKPENYTNSNVNRLPTMITDRYTLASRSTTSRLLQSYLNNFHPYCPIVHSPTLMMLYNNQIEIASKDQWQILFNCILAIGAWCIEGESTDIDVFYYQNAKSHLTSKVFESGSIILVTALHLLSRYTQWRQKTNTSYNFHSFSIRMAISLGLNRDLPSSFSDSSILEQRRRIWWSVYSWEIQLSLLYGRSIQLSQNTISFPSSVDDVQRTTTGPTIYHGIIETARLLQVFTKIYELDKTVTAEKSPICAKKCLMICNEIEEVSRQAPKFLQMDISTTALTNLLKEHPWLSFTRFELKWKQLSLIIYVLRDFFTNFTQKKSQLEQDQNDHQSYEVKRCSIMLSDAAQRTVMSVSSYMDNHNVTPYFAWNCSYYLFNAVLVPIKTLLSNSKSNAENNETAQLLQQINTVLMLLKKLATFKIQTCEKYIQVLEEVCAPFLLSQCAIPLPHISYNNSNGSAIKNIVGSATIAQYPTLPEENVNNISVKYVSPGSVGPSPVPLKSGASFSDLVKLLSNRPPSRNSPVTIPRSTPSHRSVTPFLGQQQQLQSLVPLTPSALFGGANFNQSGNIADSSLSFTFTNSSNGPNLITTQTNSQALSQPIASSNVHDNFMNNEITASKIDDGNNSKPLSPGWTDQTAYNAFGITTGMFNTTTMDDVYNYLFDDEDTPPNPKKE
SIO_010081: YPL248C
subclass of: SO_0000673
so part of: YPL248C
location: complement(79711..82356)
location: region:79711-82356:-1
so has part: feature:79711-82356:-1:exon

NP_015076.1
type: Protein
SIO_000068: ncbiprotein

S000006169
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:79711-82356:-1:exon

YPL247C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL247C
so part of: sequence
location: complement(<82625..>84196)
location: region:82625-84196:-1
so has part: feature:82625-84196:-1:exon
subclass of: SO_0000010

855829
type: Gene
SIO_000068: ncbigene

position:82625:-1
position: 82625
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:84196:-1
position: 84196
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82625-84196:-1:exon

YPL247C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL247C
product: uncharacterized protein
transcript id: NM_001184061.1
SIO_010081: YPL247C
subclass of: SO_0000673
so part of: YPL247C
location: complement(<82625..>84196)
location: region:82625-84196:-1
so has part: feature:82625-84196:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:82625-84196:-1:exon

YPL247C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL247C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest
codon start: 1
product: uncharacterized protein
translation: MDPFHNGNKRSSISFGSSQRQPYNKNNYLSGTNGPSSAAQDQGRGPSPFGMSGNTTNGGNSKRNSGCDLSATYYASRSPMYSPLDFSPPVFSPNHSQLQQARGYAANIPVVSNLMNPSMASVCEYQSHYPLFGLDWSADDYVCLGSYKEDSRNKLQVLHSNDLLSWESVVDADVVYPVSKIQWVPSQLYPRKLATCSDSLRIWSVSPEERQFQEQINLSLCKYNRQHPANPAAADDMKVIGTFPPITSFDWNTVDTNLIISSSIDTTCIVWDLQSSHYVKTQLIAHDSEVFDVRFLTKSTQLFASCGGDGSVRVFDLRSLAHSTIIYEPPSSSVSGATAGTITPSSKGSDALLRLEPSPYDPNVLATFAADSNKIIILDMRNPESPILNLQGHGSSVNGIKWHPTKRNVLLSCGDDCQVLYWDLNSSFMEINAAGSKSPSIHGTSLEDPDGDTEMTDGGAGSGLNEDPLSLNNNSKQVCKTLETPNMMYANKTQEINNIAWRPQRGDWFGCVSGKKFQNVRVL
SIO_010081: YPL247C
subclass of: SO_0000673
so part of: YPL247C
location: complement(82625..84196)
location: region:82625-84196:-1
so has part: feature:82625-84196:-1:exon

NP_015077.1
type: Protein
SIO_000068: ncbiprotein

S000006168
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:82625-84196:-1:exon

YPL246C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RBD2
locus tag: YPL246C
so part of: sequence
location: complement(<84509..>85297)
location: region:84509-85297:-1
so has part: feature:84509-85297:-1:exon
subclass of: SO_0000010

855830
type: Gene
SIO_000068: ncbigene

position:84509:-1
position: 84509
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:85297:-1
position: 85297
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84509-85297:-1:exon

YPL246C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RBD2
locus tag: YPL246C
product: putative rhomboid protease RBD2
transcript id: NM_001184060.1
SIO_010081: YPL246C
subclass of: SO_0000673
so part of: YPL246C
location: complement(<84509..>85297)
location: region:84509-85297:-1
so has part: feature:84509-85297:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:84509-85297:-1:exon

YPL246C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RBD2
locus tag: YPL246C
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030137 COPI-coated vesicle [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:25817432]
note: Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p
codon start: 1
product: putative rhomboid protease RBD2
translation: MNWKSYVFPGGHPPAALTTGLVVFLTAIYLLSFIFALREDLSLAPESLFKLQMSRLSLYPLIHLSLPHLLFNVLAIWAPLNLFEETHGTVYTGVFLNLSALFAGILYCLLGKLLYPEALVAGASGWCFTLFAYYSFKESQIRPRTRIFRTDYSIPTLYTPLVLLVAIAVVIPGSSFWGHFFGLCVGYAIGYKESWFNKITPPGWIITKIEKSLDGLIRLIPWGIKYYRDEDIDRTKDYEPLMSTETPLPLHNDNSGTVLGTA
SIO_010081: YPL246C
subclass of: SO_0000673
so part of: YPL246C
location: complement(84509..85297)
location: region:84509-85297:-1
so has part: feature:84509-85297:-1:exon

NP_015078.1
type: Protein
SIO_000068: ncbiprotein

S000006167
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:84509-85297:-1:exon

YPL245W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL245W
so part of: sequence
location: <85586..>86950
location: region:85586-86950:1
so has part: feature:85586-86950:1:exon
subclass of: SO_0000010

855831
type: Gene
SIO_000068: ncbigene

position:85586:1
position: 85586
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:86950:1
position: 86950
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:85586-86950:1:exon

YPL245W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL245W
product: uncharacterized protein
transcript id: NM_001184059.1
SIO_010081: YPL245W
subclass of: SO_0000673
so part of: YPL245W
location: <85586..>86950
location: region:85586-86950:1
so has part: feature:85586-86950:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:85586-86950:1:exon

YPL245W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL245W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
codon start: 1
product: uncharacterized protein
translation: MHGPTSKAISRNVRSVKRPRRAPRPVVSTQAMNKLSNVTLSAEQEKLRERVLSFMRSNLSQYKSDWKHPAMFVIQGDAGTGKSVILNSLFNEIQKLSQFSPSSEDILHGTHNYLVVNHPEMLKLYIRISDSFKYISKSSLERPTSLINNLQKRKVMADVVIVDEAHLLATSKDAFKRFYGENHLKDLMSLCKVLVLVYDDKQALRMGSYWDEGSNNGATLKDFYNEIPPKSRDWYTLKQQFRVAAPQNVLNWIDQISVAGKIPPIESVLSKGNADCADDKIKNFDFKIWDDCGAMYEAIKEKDRQYGQCRMLSTYDFPYRLDGKDYYVECGDNFKVRWDRYTPREVTPWSERCDTIDEVGSVYTIQGFDLNYAGVILGRSIGYDAANDCIKLRPELYDDRAGFTKKKNIHNAEDVKQKIIMNSINVLLTRGVRGLYVYAYDPELRERLLRPSKK
SIO_010081: YPL245W
subclass of: SO_0000673
so part of: YPL245W
location: 85586..86950
location: region:85586-86950:1
so has part: feature:85586-86950:1:exon

NP_015079.1
type: Protein
SIO_000068: ncbiprotein

S000006166
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:85586-86950:1:exon

YPL244C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HUT1
locus tag: YPL244C
so part of: sequence
location: complement(<87014..>88033)
location: region:87014-88033:-1
so has part: feature:87014-88033:-1:exon
subclass of: SO_0000010

855832
type: Gene
SIO_000068: ncbigene

position:87014:-1
position: 87014
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:88033:-1
position: 88033
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87014-88033:-1:exon

YPL244C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HUT1
locus tag: YPL244C
product: UDP-galactose transporter HUT1
transcript id: NM_001184058.1
SIO_010081: YPL244C
subclass of: SO_0000673
so part of: YPL244C
location: complement(<87014..>88033)
location: region:87014-88033:-1
so has part: feature:87014-88033:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87014-88033:-1:exon

YPL244C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HUT1
locus tag: YPL244C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0015786 UDP-glucose transmembrane transport [PMID:18693752]
experiment: EXISTENCE:mutant phenotype:GO:0015786 UDP-glucose transmembrane transport [PMID:18693752]
experiment: EXISTENCE:mutant phenotype:GO:0072334 UDP-galactose transmembrane transport [PMID:11284009]
note: Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1
codon start: 1
product: UDP-galactose transporter HUT1
translation: MAGSTSSLVICAIGIYATFLTWALVQEPLATRTWPNSMGKFQFPNVISLIQASVAMMMGYLYLNWKKVEYPPRKMIKDHWKQLMLISFTQSSSGPLATTSLKHVDYLTYMLAKSCKMIPVLLVHLLLYRTPIASQKKVVALLVSLGVTIFTIGGNDGKKLKRSFNESGNDNKLQGFGLLFSSLFLDGLTNATQDKLLKANKAKEKGKQTLITGAHLMFTLNLFVILWNILYFIVIDCKQWDNAVSVLTMDPQVWGYLMLYSFCGAMGQCFIFYTLEQFGSLVLIMITVTRKMVSMILSIIVFGKSVRFQQWVGMFIVFGGITWEALNKKKANIPKAKSA
SIO_010081: YPL244C
subclass of: SO_0000673
so part of: YPL244C
location: complement(87014..88033)
location: region:87014-88033:-1
so has part: feature:87014-88033:-1:exon

NP_015080.1
type: Protein
SIO_000068: ncbiprotein

S000006165
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87014-88033:-1:exon

YPL243W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SRP68
locus tag: YPL243W
so part of: sequence
location: <88517..>90316
location: region:88517-90316:1
so has part: feature:88517-90316:1:exon
subclass of: SO_0000010

855833
type: Gene
SIO_000068: ncbigene

position:88517:1
position: 88517
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90316:1
position: 90316
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:88517-90316:1:exon

YPL243W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SRP68
locus tag: YPL243W
product: signal recognition particle subunit SRP68
transcript id: NM_001184057.1
SIO_010081: YPL243W
subclass of: SO_0000673
so part of: YPL243W
location: <88517..>90316
location: region:88517-90316:1
so has part: feature:88517-90316:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:88517-90316:1:exon

YPL243W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SRP68
locus tag: YPL243W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005786 signal recognition particle, endoplasmic reticulum targeting [PMID:7925282]
experiment: EXISTENCE:direct assay:GO:0006614 SRP-dependent cotranslational protein targeting to membrane [PMID:10921896]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:22842922]
note: Core component of the signal recognition particle (SRP) complex; SRP complex functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress
codon start: 1
product: signal recognition particle subunit SRP68
translation: MVAYSPIIATYGNRAEQFLETDSDFAKYHAKLNKKLQHLRSRCHLVTKDTKKYSSKNKYGEINSEDYDNKTKLIGVLILLHAERDLALAETLKLRARQRGKLKKSEEKVLSTRLKKACKTADKLVNVTQNEQQWITRAQYLAFAKLVHSEYLINGKRFKRKDNAKISNNLALVFAALEHLKNLSLLAEEVVDNIVNKYQYSLKQYAGNLITTPEINNFIVERVQSDENKDDELVKLLLDNGFNMKKITTSTEDQKVTTNINWRSFNAKIIDAEVAQFLEQGLSIHPTQITQYTQRLSKLEKALDRHEFFIANHDDQDDIDEMVENSSENNQIILAYIKYNILLTSISRERDLFTHLWNQWLKLNTSLPSKLTKYKEMERIVKNLTKYLSDIMELPGVYSDDELLSQLDLCKLYFQLFLNTGCLSVLYQSKGRYMEALALYVDAYRRLENKLSEIESLDEILLPANLLSLNSVRSLQKRIENGGNSVITLAEYEKRNHGGSLGKYDLTVIEKLDSKKILPTDIQLKNLFPLKPKMLPIPSKPTLFDLAFNYITYDKQEPSASQVKDSVTETESISQTPISNEQTEGEPKKKRGFLGLFGR
SIO_010081: YPL243W
subclass of: SO_0000673
so part of: YPL243W
location: 88517..90316
location: region:88517-90316:1
so has part: feature:88517-90316:1:exon

NP_015081.1
type: Protein
SIO_000068: ncbiprotein

S000006164
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:88517-90316:1:exon

YPL242C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CYK1
gene: IQG1
locus tag: YPL242C
gene synonym: CYK1
so part of: sequence
location: complement(<90622..>95109)
location: region:90622-95109:-1
so has part: feature:90622-95109:-1:exon
subclass of: SO_0000010

855834
type: Gene
SIO_000068: ncbigene

position:90622:-1
position: 90622
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95109:-1
position: 95109
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90622-95109:-1:exon

YPL242C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CYK1
gene: IQG1
locus tag: YPL242C
gene synonym: CYK1
product: Iqg1p
transcript id: NM_001184056.1
SIO_010081: YPL242C
subclass of: SO_0000673
so part of: YPL242C
location: complement(<90622..>95109)
location: region:90622-95109:-1
so has part: feature:90622-95109:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:90622-95109:-1:exon

YPL242C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CYK1
gene: IQG1
locus tag: YPL242C
gene synonym: CYK1
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:9382845|PMID:9442111|PMID:9950677|PMID:10873803]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11082046|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0051015 actin filament binding [PMID:9382845|PMID:9950677]
experiment: EXISTENCE:direct assay:GO:0120155 MIH complex [PMID:24895401]
experiment: EXISTENCE:mutant phenotype:GO:0051015 actin filament binding [PMID:9382845|PMID:9950677]
experiment: EXISTENCE:mutant phenotype:GO:0072741 protein localization to cell division site [PMID:21173112]
experiment: EXISTENCE:mutant phenotype:GO:1903471 regulation of mitotic actomyosin contractile ring contraction [PMID:9950677|PMID:19109423|PMID:26085509|PMID:24895401]
experiment: EXISTENCE:mutant phenotype:GO:1903475 mitotic actomyosin contractile ring assembly [PMID:11082046|PMID:21173112]
experiment: EXISTENCE:mutant phenotype:GO:1903479 mitotic actomyosin contractile ring assembly actin filament organization [PMID:9382845|PMID:9442111|PMID:9950677]
experiment: EXISTENCE:physical interaction:GO:0005516 calmodulin binding [PMID:9950677]
experiment: EXISTENCE:physical interaction:GO:0032027 myosin light chain binding [PMID:10873803]
experiment: EXISTENCE:physical interaction:GO:0032033 myosin II light chain binding [PMID:11082046]
experiment: EXISTENCE:physical interaction:GO:0032038 myosin II heavy chain binding [PMID:11082046]
experiment: EXISTENCE:physical interaction:GO:0120155 MIH complex [PMID:24895401]
note: Actin filament binding protein that enhances actin ring formation; IQGAP family member required for assembly and contraction of the AMR, prior to cytokinesis; localizes to the contractile ring during anaphase in an Mlc1p-dependent manner, recruiting Myo1p and Hof1p to the site, and promoting cytokinetic core complex assembly; specifies bud-site selection, localizing axial markers Bud4p and Cdc12p; regulated by Cdc28p; relocalizes from the bud neck to the cytoplasm upon replication stress
codon start: 1
product: Iqg1p
translation: MTAYSGSPSKPGNNNSYLNRYVENLGTNVTPPLRPQSSSKINSSLNIASPSHLKTKTSASNSSATILSKKVESSVSKLKPSLPNKLVGKYTVDLSNYSKIELRYYEFLCRVSEVKIWIEAVIEEALPSEIELCVGDSLRNGVFLAKLTQRINPDLTTVIFPAGDKLQFKHTQNINAFFGLVEHVGVPDSFRFELQDLYNKKNIPQVFETLHILISMINKKWPGKTPALTNVSGQISFTKEEIAACKKAWPRIRDFKSLGTNINTAPASPEEPKEKRSGLIKDFNKFERPNIPVEEILITPRKNITDANCSDFSNTPSPYNEAPKMSNLDVVVEKRKFTPIEPSLLGPTPSLEYSPIKNKSLSYYSPTISKYLTYDTEFYTRRSRAREEDLNYYQTFKYSPSHYSPMRRERMTEEQFLEKVVQLQNICRGVNTRFNLYIQKRLLNLFEQDILRFQACLRGNKFRVLSSMYLPIRRAKIDVPHVEAIQSRIKGSRIRYKYDKLKFTLSRFSCTVELLQAYCRSKLLKTTVNTKLNDIEISHYPLTKLQSYMRASYVRKKVMSLNTKLNDERESIMKFSAIIRGNVVRCSEDAILSAVHDVHKENISKLQSLIRGIFTRSCLASIIYSLGKENCNIIQLSACIRGNAVRHKVQSLFAPENNLSETVHDLQGLVRGILVRYTLDLVDDIVEYNNLALFQAFSRGALVRESLDQKSSFYKRNVRSVIMIQSWIRKSLQRSAYLELLDCPNPSLWAVKKFVHLLNGTATIEEVQNQLESCQASLDSENMKKERLLKSIRQQLNINGVLDKFGLLKDKDHELGISDSTIPKSKYQKYEKLFYMLQVDPSYWKLLYLKEPEFVAKNVYMTFGTVNQRMNDRERSYFTRFVCEMLQNAINEAPSIESFLDNRSQFWQTILQDFLRRESPEFFSIIVPVLDYLSDPVVDFESDPYKIYQEIHGFSSPQHCSPVDDASTKNKFIDNLRCLWHAIEMVAEIYTRKVHTIPVEIRYLCTKIFCYAADKNIEEIDSLRAISSILVNVFVSEYLVNREYYGYKDSNVQKNNQKIDILMKSLATVFEIKNFDGFLDPLNQYANEIKPHIKDVLYNVLVDPEYEQEGDRLIYLDMVSPSPKLELLTEKVLEISGKFEEYLNEFPEADILHDILEKNLDNSSFPRSGRVTLELDASAYRFLVSDDKMRKIYDQVKRAFVYMMQIEDVDTNLYDLSISTILPQDEPNFANFLEQNPKIRDDPMIQKLKPLKYFTLKNVTLKKIHELESTGTFCSSDNKLQNFLNDIANTIKNPNYAIDYVTQEIYITKETLTKISEMNHSLDIELSRLKKHVDHTIKDFQKAKDFSPVHKSKFGNFKNAVKKVQGRERSELQGMKFKWNTKQLYERGVLKTIRGEKLAELTVKVFGSSGPKFPDIIFKISTSDGSRFGIQMIDKRKGPDKRYSDDVDSFSFKDLIKTQVEPKIETWKLFHSNVVVNNSQLLHLIVSFFYKRNAL
SIO_010081: YPL242C
subclass of: SO_0000673
so part of: YPL242C
location: complement(90622..95109)
location: region:90622-95109:-1
so has part: feature:90622-95109:-1:exon

NP_015082.1
type: Protein
SIO_000068: ncbiprotein

S000006163
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90622-95109:-1:exon

YPL241C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CIN2
locus tag: YPL241C
so part of: sequence
location: complement(<95372..>96258)
location: region:95372-96258:-1
so has part: feature:95372-96258:-1:exon
subclass of: SO_0000010

855835
type: Gene
SIO_000068: ncbigene

position:95372:-1
position: 95372
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:96258:-1
position: 96258
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:95372-96258:-1:exon

YPL241C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CIN2
locus tag: YPL241C
product: GTPase-activating protein CIN2
transcript id: NM_001184055.1
SIO_010081: YPL241C
subclass of: SO_0000673
so part of: YPL241C
location: complement(join(<95372..96153,96234..>96258))
location: region:95372-96258:-1
so has part: feature:96234-96258:-1:exon
so has part: feature:95372-96153:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96234-96258:-1:exon

position:96234:-1
position: 96234
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:95372-96153:-1:exon

position:96153:-1
position: 96153
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL241C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CIN2
locus tag: YPL241C
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:18376416]
experiment: EXISTENCE:genetic interaction:GO:0006457 protein folding [PMID:2407611]
experiment: EXISTENCE:genetic interaction:GO:0007021 tubulin complex assembly [PMID:9215891]
experiment: EXISTENCE:mutant phenotype:GO:0007021 tubulin complex assembly [PMID:9215891]
note: GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; human homolog RP2 complements yeast null mutant
codon start: 1
product: GTPase-activating protein CIN2
translation: MDFTAKIKELERELSETSDYKTLQKKTISLRSELNTLSHSLTSYEKEHFSNDIENVLKSINAKLSESKGKKRLFSFKQKNSSSAVHKNVERTELANAPAYTTTLKKHYVLEKGDSAFENLEFCTVTSTTDYSGNSALSGSLCFRNITKCVINLQRIFFQTGSIFITDCTDSIIFLRSPSDKDFQIRLRDLKNCKILIEKLSPSIDCKQVVIIENCHKCIFNASTRDHLIIQDFSNPFQSEETEDNSAFAFEDFDICNKDTMQLFRAYL
SIO_010081: YPL241C
subclass of: SO_0000673
so part of: YPL241C
location: complement(join(95372..96153,96234..96258))
location: region:95372-96258:-1
so has part: feature:96234-96258:-1:exon
so has part: feature:95372-96153:-1:exon

NP_015083.1
type: Protein
SIO_000068: ncbiprotein

S000006162
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96234-96258:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:95372-96153:-1:exon

YPL240C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HSP90
gene: HSP82
locus tag: YPL240C
gene synonym: HSP90
so part of: sequence
location: complement(<96496..>98625)
location: region:96496-98625:-1
so has part: feature:96496-98625:-1:exon
subclass of: SO_0000010

855836
type: Gene
SIO_000068: ncbigene

position:96496:-1
position: 96496
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:98625:-1
position: 98625
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:96496-98625:-1:exon

YPL240C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HSP90
gene: HSP82
locus tag: YPL240C
gene synonym: HSP90
product: Hsp90 family chaperone HSP82
transcript id: NM_001184054.1
SIO_010081: YPL240C
subclass of: SO_0000673
so part of: YPL240C
location: complement(<96496..>98625)
location: region:96496-98625:-1
so has part: feature:96496-98625:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96496-98625:-1:exon

YPL240C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HSP90
gene: HSP82
locus tag: YPL240C
gene synonym: HSP90
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:32920053]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:27385335|PMID:32920053|PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006458 'de novo' protein folding [PMID:10564510]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:12235160]
experiment: EXISTENCE:direct assay:GO:0032212 positive regulation of telomere maintenance via telomerase [PMID:17954556]
experiment: EXISTENCE:direct assay:GO:0043248 proteasome assembly [PMID:12853471]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:10564510]
experiment: EXISTENCE:mutant phenotype:GO:0000492 box C/D snoRNP assembly [PMID:18268103]
experiment: EXISTENCE:mutant phenotype:GO:0006458 'de novo' protein folding [PMID:9371781]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:16487343]
experiment: EXISTENCE:mutant phenotype:GO:0016887 ATP hydrolysis activity [PMID:27068472]
experiment: EXISTENCE:mutant phenotype:GO:0032212 positive regulation of telomere maintenance via telomerase [PMID:17954556]
experiment: EXISTENCE:mutant phenotype:GO:0042026 protein refolding [PMID:9371781]
experiment: EXISTENCE:mutant phenotype:GO:0043248 proteasome assembly [PMID:12853471]
experiment: EXISTENCE:mutant phenotype:GO:0051604 protein maturation [PMID:27068472]
experiment: EXISTENCE:physical interaction:GO:0006626 protein targeting to mitochondrion [PMID:12526792]
note: Hsp90 chaperone; functionally redundant with Hsc82p; required for pheromone signaling; negative regulator of the Hsf1p-dependent heat shock response with Cpr7p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; promotes solubility of chaperone-substrate complexes; DNA damage induced nuclear import is Aha1p dependent; protein abundance increases in response to DNA replication stress; human homolog, HSP90AB1, complements null mutant
codon start: 1
product: Hsp90 family chaperone HSP82
translation: MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTEMEEVD
SIO_010081: YPL240C
subclass of: SO_0000673
so part of: YPL240C
location: complement(96496..98625)
location: region:96496-98625:-1
so has part: feature:96496-98625:-1:exon

NP_015084.1
type: Protein
SIO_000068: ncbiprotein

S000006161
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96496-98625:-1:exon

YPL239W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAR1
locus tag: YPL239W
so part of: sequence
location: <99484..>100086
location: region:99484-100086:1
so has part: feature:99484-100086:1:exon
subclass of: SO_0000010

855837
type: Gene
SIO_000068: ncbigene

position:99484:1
position: 99484
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:100086:1
position: 100086
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99484-100086:1:exon

YPL239W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAR1
locus tag: YPL239W
product: Yar1p
transcript id: NM_001184053.1
SIO_010081: YPL239W
subclass of: SO_0000673
so part of: YPL239W
location: <99484..>100086
location: region:99484-100086:1
so has part: feature:99484-100086:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:99484-100086:1:exon

YPL239W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAR1
locus tag: YPL239W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22570489]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:26112308]
experiment: EXISTENCE:genetic interaction:GO:0000056 ribosomal small subunit export from nucleus [PMID:22570489]
experiment: EXISTENCE:genetic interaction:GO:0005634 nucleus [PMID:22570489]
experiment: EXISTENCE:genetic interaction:GO:0042274 ribosomal small subunit biogenesis [PMID:15611164]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:22570489]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:15611164]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:22570489]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:15611164]
experiment: EXISTENCE:mutant phenotype:GO:0042274 ribosomal small subunit biogenesis [PMID:15611164]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:22570489]
experiment: EXISTENCE:physical interaction:GO:0032880 regulation of protein localization [PMID:22570489]
note: Nucleocytoplasmic shuttling assembly chaperone; co-translationally associates with nascent Rps3p in the cytoplasm and delivers it to pre-ribosomal subunits in the nucleus; required for 40S ribosomal subunit nuclear export, biogenesis and adaptation to osmotic and oxidative stress; contains ankyrin-repeats; expression repressed by heat shock
codon start: 1
product: Yar1p
translation: MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALREETEKLNINKD
SIO_010081: YPL239W
subclass of: SO_0000673
so part of: YPL239W
location: 99484..100086
location: region:99484-100086:1
so has part: feature:99484-100086:1:exon

NP_015085.1
type: Protein
SIO_000068: ncbiprotein

S000006160
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99484-100086:1:exon

YPL237W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUI3
locus tag: YPL237W
so part of: sequence
location: <100496..>101353
location: region:100496-101353:1
so has part: feature:100496-101353:1:exon
subclass of: SO_0000010

855838
type: Gene
SIO_000068: ncbigene

position:100496:1
position: 100496
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101353:1
position: 101353
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100496-101353:1:exon

YPL237W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SUI3
locus tag: YPL237W
product: translation initiation factor eIF2 subunit beta
transcript id: NM_001184051.1
SIO_010081: YPL237W
subclass of: SO_0000673
so part of: YPL237W
location: <100496..>101353
location: region:100496-101353:1
so has part: feature:100496-101353:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:100496-101353:1:exon

YPL237W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SUI3
locus tag: YPL237W
experiment: EXISTENCE:direct assay:GO:0001731 formation of translation preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:9858542]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:14698289|PMID:16246727]
experiment: EXISTENCE:direct assay:GO:0005850 eukaryotic translation initiation factor 2 complex [PMID:12137565]
experiment: EXISTENCE:direct assay:GO:0016282 eukaryotic 43S preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0031369 translation initiation factor binding [PMID:15145951|PMID:9395514|PMID:22683627]
experiment: EXISTENCE:direct assay:GO:0043614 multi-eIF complex [PMID:15838098|PMID:11018020]
experiment: EXISTENCE:direct assay:GO:1990856 methionyl-initiator methionine tRNA binding [PMID:16565414]
experiment: EXISTENCE:mutant phenotype:GO:0001731 formation of translation preinitiation complex [PMID:16449648]
experiment: EXISTENCE:mutant phenotype:GO:0003743 translation initiation factor activity [PMID:12137565]
experiment: EXISTENCE:mutant phenotype:GO:0005850 eukaryotic translation initiation factor 2 complex [PMID:12137565]
experiment: EXISTENCE:physical interaction:GO:0031369 translation initiation factor binding [PMID:9395514|PMID:15145951|PMID:22683627]
note: Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding
codon start: 1
product: translation initiation factor eIF2 subunit beta
translation: MSSDLAAELGFDPALKKKKKTKKVIPDDFDAAVNGKENGSGDDLFAGLKKKKKKSKSVSADAEAEKEPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKAGLDNVDAESKEGTPSANSSIQQEVGLPYSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDGKKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRRRM
SIO_010081: YPL237W
subclass of: SO_0000673
so part of: YPL237W
location: 100496..101353
location: region:100496-101353:1
so has part: feature:100496-101353:1:exon

NP_015087.1
type: Protein
SIO_000068: ncbiprotein

S000006158
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:100496-101353:1:exon

YPL236C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ENV7
locus tag: YPL236C
so part of: sequence
location: complement(<101608..>102702)
location: region:101608-102702:-1
so has part: feature:101608-102702:-1:exon
subclass of: SO_0000010

855840
type: Gene
SIO_000068: ncbigene

position:101608:-1
position: 101608
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:102702:-1
position: 102702
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101608-102702:-1:exon

YPL236C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ENV7
locus tag: YPL236C
product: putative serine/threonine protein kinase ENV7
transcript id: NM_001184050.1
SIO_010081: YPL236C
subclass of: SO_0000673
so part of: YPL236C
location: complement(<101608..>102702)
location: region:101608-102702:-1
so has part: feature:101608-102702:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101608-102702:-1:exon

YPL236C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ENV7
locus tag: YPL236C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006624 vacuolar protein processing [PMID:21912603]
experiment: EXISTENCE:mutant phenotype:GO:0032889 regulation of vacuole fusion, non-autophagic [PMID:24610781]
note: Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; targeted to vacuole via AP-3 pathway; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16)
codon start: 1
product: putative serine/threonine protein kinase ENV7
translation: MISIVLELFQNLCCCRGFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQSPYVIKSIDSQVMQEKDGSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLNLLQDLDT
SIO_010081: YPL236C
subclass of: SO_0000673
so part of: YPL236C
location: complement(101608..102702)
location: region:101608-102702:-1
so has part: feature:101608-102702:-1:exon

NP_015088.1
type: Protein
SIO_000068: ncbiprotein

S000006157
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101608-102702:-1:exon

YPL235W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TIH2
alternative label: TIP48
alternative label: TIP49B
gene: RVB2
locus tag: YPL235W
gene synonym: TIH2; TIP48; TIP49B
so part of: sequence
location: <103232..>104647
location: region:103232-104647:1
so has part: feature:103232-104647:1:exon
subclass of: SO_0000010

855841
type: Gene
SIO_000068: ncbigene

position:103232:1
position: 103232
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:104647:1
position: 104647
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:103232-104647:1:exon

YPL235W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TIH2
alternative label: TIP48
alternative label: TIP49B
gene: RVB2
locus tag: YPL235W
gene synonym: TIH2; TIP48; TIP49B
product: RuvB family ATP-dependent DNA helicase reptin
transcript id: NM_001184049.1
SIO_010081: YPL235W
subclass of: SO_0000673
so part of: YPL235W
location: <103232..>104647
location: region:103232-104647:1
so has part: feature:103232-104647:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:103232-104647:1:exon

YPL235W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TIH2
alternative label: TIP48
alternative label: TIP49B
gene: RVB2
locus tag: YPL235W
gene synonym: TIH2; TIP48; TIP49B
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0000812 Swr1 complex [PMID:16299513]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11604509]
experiment: EXISTENCE:direct assay:GO:0043138 3'-5' DNA helicase activity [PMID:10952318|PMID:20553504]
experiment: EXISTENCE:direct assay:GO:0043139 5'-3' DNA helicase activity [PMID:18234224]
experiment: EXISTENCE:direct assay:GO:0070209 ASTRA complex [PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0097255 R2TP complex [PMID:15766533]
experiment: EXISTENCE:mutant phenotype:GO:0000492 box C/D snoRNP assembly [PMID:11604509|PMID:18268103]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:11278922]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:11604509]
experiment: EXISTENCE:physical interaction:GO:0000812 Swr1 complex [PMID:14645854|PMID:14690608]
experiment: EXISTENCE:physical interaction:GO:0006338 chromatin remodeling [PMID:14690608]
experiment: EXISTENCE:physical interaction:GO:0031011 Ino80 complex [PMID:10952318|PMID:24034245]
experiment: EXISTENCE:physical interaction:GO:0097255 R2TP complex [PMID:18268103]
note: ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly
codon start: 1
product: RuvB family ATP-dependent DNA helicase reptin
translation: MSIQTSDPNETSDLKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPSTGKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGADTRFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVMMATNRGVSKTRGTNYKSPHGLPLDLLDRSIIITTKSYNEQEIKTILSIRAQEEEVELSSDALDLLTKTGVETSLRYSSNLISVAQQIAMKRKNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYIDDQGNVQISIAKSADPDAMDTTE
SIO_010081: YPL235W
subclass of: SO_0000673
so part of: YPL235W
location: 103232..104647
location: region:103232-104647:1
so has part: feature:103232-104647:1:exon

NP_015089.1
type: Protein
SIO_000068: ncbiprotein

S000006156
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:103232-104647:1:exon

YPL234C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLS9
alternative label: TFP3
gene: VMA11
locus tag: YPL234C
gene synonym: CLS9; TFP3
so part of: sequence
location: complement(<104946..>105440)
location: region:104946-105440:-1
so has part: feature:104946-105440:-1:exon
subclass of: SO_0000010

855842
type: Gene
SIO_000068: ncbigene

position:104946:-1
position: 104946
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:105440:-1
position: 105440
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:104946-105440:-1:exon

YPL234C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLS9
alternative label: TFP3
gene: VMA11
locus tag: YPL234C
gene synonym: CLS9; TFP3
product: H(+)-transporting V0 sector ATPase subunit c'
transcript id: NM_001184048.1
SIO_010081: YPL234C
subclass of: SO_0000673
so part of: YPL234C
location: complement(<104946..>105440)
location: region:104946-105440:-1
so has part: feature:104946-105440:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:104946-105440:-1:exon

YPL234C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLS9
alternative label: TFP3
gene: VMA11
locus tag: YPL234C
gene synonym: CLS9; TFP3
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:11853670]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:15252052]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Vacuolar ATPase V0 domain subunit c'; involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen
codon start: 1
product: H(+)-transporting V0 sector ATPase subunit c'
translation: MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
SIO_010081: YPL234C
subclass of: SO_0000673
so part of: YPL234C
location: complement(104946..105440)
location: region:104946-105440:-1
so has part: feature:104946-105440:-1:exon

NP_015090.1
type: Protein
SIO_000068: ncbiprotein

S000006155
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:104946-105440:-1:exon

YPL233W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NSL1
locus tag: YPL233W
so part of: sequence
location: <106172..>106822
location: region:106172-106822:1
so has part: feature:106172-106822:1:exon
subclass of: SO_0000010

855843
type: Gene
SIO_000068: ncbigene

position:106172:1
position: 106172
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106822:1
position: 106822
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106172-106822:1:exon

YPL233W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NSL1
locus tag: YPL233W
product: MIND complex subunit NSL1
transcript id: NM_001184047.1
SIO_010081: YPL233W
subclass of: SO_0000673
so part of: YPL233W
location: <106172..>106822
location: region:106172-106822:1
so has part: feature:106172-106822:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106172-106822:1:exon

YPL233W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NSL1
locus tag: YPL233W
experiment: EXISTENCE:direct assay:GO:0000444 MIS12/MIND type complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:14657030]
experiment: EXISTENCE:direct assay:GO:0000922 spindle pole [PMID:12455957]
experiment: EXISTENCE:direct assay:GO:0007059 chromosome segregation [PMID:12455957]
note: Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)
codon start: 1
product: MIND complex subunit NSL1
translation: MSQGQSKKLDVTVEQLRSIYHQFHDILEEKTDLHLPKKEYDDDAVRREVQIQLQEFLLSAMTMASKSLEVVNADTVGKTVKQLIMESQEKYMEPFDLDLNEQVRKMYQEWEDETVKVAQLRQTGPAKINEVYNNSKDEYLAQLDGRIGVLQARMMQQQSADHDDSTDDADDHINWEHIKQDYVASLNELYQTQQDLPKVRYNVEKVKRLMDFLEED
SIO_010081: YPL233W
subclass of: SO_0000673
so part of: YPL233W
location: 106172..106822
location: region:106172-106822:1
so has part: feature:106172-106822:1:exon

NP_015091.1
type: Protein
SIO_000068: ncbiprotein

S000006154
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106172-106822:1:exon

YPL232W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SSO1
locus tag: YPL232W
so part of: sequence
location: <107275..>108147
location: region:107275-108147:1
so has part: feature:107275-108147:1:exon
subclass of: SO_0000010

855844
type: Gene
SIO_000068: ncbigene

position:107275:1
position: 107275
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:108147:1
position: 108147
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107275-108147:1:exon

YPL232W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SSO1
locus tag: YPL232W
product: syntaxin
transcript id: NM_001184046.1
SIO_010081: YPL232W
subclass of: SO_0000673
so part of: YPL232W
location: <107275..>108147
location: region:107275-108147:1
so has part: feature:107275-108147:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:107275-108147:1:exon

YPL232W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SSO1
locus tag: YPL232W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19502581]
experiment: EXISTENCE:direct assay:GO:0005484 SNAP receptor activity [PMID:16339720]
experiment: EXISTENCE:direct assay:GO:0005546 phosphatidylinositol-4,5-bisphosphate binding [PMID:19502581]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:17298976|PMID:19502581]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:17298976|PMID:19502581|PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0006906 vesicle fusion [PMID:11001046]
experiment: EXISTENCE:direct assay:GO:0031201 SNARE complex [PMID:9195974]
experiment: EXISTENCE:direct assay:GO:0043325 phosphatidylinositol-3,4-bisphosphate binding [PMID:19502581]
experiment: EXISTENCE:direct assay:GO:0070300 phosphatidic acid binding [PMID:19502581]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0080025 phosphatidylinositol-3,5-bisphosphate binding [PMID:19502581]
experiment: EXISTENCE:genetic interaction:GO:0031321 ascospore-type prospore assembly [PMID:19502581]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:11839791]
experiment: EXISTENCE:mutant phenotype:GO:0031321 ascospore-type prospore assembly [PMID:16554438|PMID:19502581]
experiment: EXISTENCE:physical interaction:GO:0005484 SNAP receptor activity [PMID:7954793|PMID:10924463]
note: Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p; SSO1 has a paralog, SSO2, that arose from the whole genome duplication
codon start: 1
product: syntaxin
translation: MSYNNPYQLETPFEESYELDEGSSAIGAEGHDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR
SIO_010081: YPL232W
subclass of: SO_0000673
so part of: YPL232W
location: 107275..108147
location: region:107275-108147:1
so has part: feature:107275-108147:1:exon

NP_015092.1
type: Protein
SIO_000068: ncbiprotein

S000006153
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107275-108147:1:exon

YPL231W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAS2
locus tag: YPL231W
so part of: sequence
location: <108652..>114315
location: region:108652-114315:1
so has part: feature:108652-114315:1:exon
subclass of: SO_0000010

855845
type: Gene
SIO_000068: ncbigene

position:108652:1
position: 108652
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:114315:1
position: 114315
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:108652-114315:1:exon

YPL231W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAS2
locus tag: YPL231W
product: trifunctional fatty acid synthase subunit FAS2
transcript id: NM_001184045.1
SIO_010081: YPL231W
subclass of: SO_0000673
so part of: YPL231W
location: <108652..>114315
location: region:108652-114315:1
so has part: feature:108652-114315:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:108652-114315:1:exon

YPL231W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAS2
locus tag: YPL231W
EC number: 1.1.1.100
EC number: 2.3.1.41
EC number: 2.3.1.86
experiment: EXISTENCE:direct assay:GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [PMID:365179]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:6025308|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005835 fatty acid synthase complex [PMID:65153]
experiment: EXISTENCE:mutant phenotype:GO:0004312 fatty acid synthase activity [PMID:65153]
experiment: EXISTENCE:mutant phenotype:GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity [PMID:1100391]
experiment: EXISTENCE:mutant phenotype:GO:0008897 holo-[acyl-carrier-protein] synthase activity [PMID:10785388]
experiment: EXISTENCE:mutant phenotype:GO:0042759 long-chain fatty acid biosynthetic process [PMID:1735446]
note: Alpha subunit of fatty acid synthetase; complex catalyzes the synthesis of long-chain saturated fatty acids; contains the acyl-carrier protein domain and beta-ketoacyl reductase, beta-ketoacyl synthase and self-pantetheinylation activities
codon start: 1
product: trifunctional fatty acid synthase subunit FAS2
translation: MKPEVEQELAHILLTELLAYQFASPVRWIETQDVFLKDFNTERVVEIGPSPTLAGMAQRTLKNKYESYDAALSLHREILCYSKDAKEIYYTPDPSELAAKEEPAKEEAPAPTPAASAPAPAAAAPAPVAAAAPAAAAAEIADEPVKASLLLHVLVAHKLKKSLDSIPMSKTIKDLVGGKSTVQNEILGDLGKEFGTTPEKPEETPLEELAETFQDTFSGALGKQSSSLLSRLISSKMPGGFTITVARKYLQTRWGLPSGRQDGVLLVALSNEPAARLGSEADAKAFLDSMAQKYASIVGVDLSSAASASGAAGAGAAAGAAMIDAGALEEITKDHKVLARQQLQVLARYLKMDLDNGERKFLKEKDTVAELQAQLDYLNAELGEFFVNGVATSFSRKKARTFDSSWNWAKQSLLSLYFEIIHGVLKNVDREVVSEAINIMNRSNDALIKFMEYHISNTDETKGENYQLVKTLGEQLIENCKQVLDVDPVYKDVAKPTGPKTAIDKNGNITYSEEPREKVRKLSQYVQEMALGGPITKESQPTIEEDLTRVYKAISAQADKQDISSSTRVEFEKLYSDLMKFLESSKEIDPSQTTQLAGMDVEDALDKDSTKEVASLPNKSTISKTVSSTIPRETIPFLHLRKKTPAGDWKYDRQLSSLFLDGLEKAAFNGVTFKDKYVLITGAGKGSIGAEVLQGLLQGGAKVVVTTSRFSKQVTDYYQSIYAKYGAKGSTLIVVPFNQGSKQDVEALIEFIYDTEKNGGLGWDLDAIIPFAAIPEQGIELEHIDSKSEFAHRIMLTNILRMMGCVKKQKSARGIETRPAQVILPMSPNHGTFGGDGMYSESKLSLETLFNRWHSESWANQLTVCGAIIGWTRGTGLMSANNIIAEGIEKMGVRTFSQKEMAFNLLGLLTPEVVELCQKSPVMADLNGGLQFVPELKEFTAKLRKELVETSEVRKAVSIETALEHKVVNGNSADAAYAQVEIQPRANIQLDFPELKPYKQVKQIAPAELEGLLDLERVIVVTGFAEVGPWGSARTRWEMEAFGEFSLEGCVEMAWIMGFISYHNGNLKGRPYTGWVDSKTKEPVDDKDVKAKYETSILEHSGIRLIEPELFNGYNPEKKEMIQEVIVEEDLEPFEASKETAEQFKHQHGDKVDIFEIPETGEYSVKLLKGATLYIPKALRFDRLVAGQIPTGWNAKTYGISDDIISQVDPITLFVLVSVVEAFIASGITDPYEMYKYVHVSEVGNCSGSGMGGVSALRGMFKDRFKDEPVQNDILQESFINTMSAWVNMLLISSSGPIKTPVGACATSVESVDIGVETILSGKARICIVGGYDDFQEEGSFEFGNMKATSNTLEEFEHGRTPAEMSRPATTTRNGFMEAQGAGIQIIMQADLALKMGVPIYGIVAMAATATDKIGRSVPAPGKGILTTAREHHSSVKYASPNLNMKYRKRQLVTREAQIKDWVENELEALKLEAEEIPSEDQNEFLLERTREIHNEAESQLRAAQQQWGNDFYKRDPRIAPLRGALATYGLTIDDLGVASFHGTSTKANDKNESATINEMMKHLGRSEGNPVIGVFQKFLTGHPKGAAGAWMMNGALQILNSGIIPGNRNADNVDKILEQFEYVLYPSKTLKTDGVRAVSITSFGFGQKGGQAIVVHPDYLYGAITEDRYNEYVAKVSAREKSAYKFFHNGMIYNKLFVSKEHAPYTDELEEDVYLDPLARVSKDKKSGSLTFNSKNIQSKDSYINANTIETAKMIENMTKEKVSNGGVGVDVELITSINVENDTFIERNFTPQEIEYCSAQPSVQSSFAGTWSAKEAVFKSLGVKSLGGGAALKDIEIVRVNKNAPAVELHGNAKKAAEEAGVTDVKVSISHDDLQAVAVAVSTKK
SIO_010081: YPL231W
subclass of: SO_0000673
so part of: YPL231W
location: 108652..114315
location: region:108652-114315:1
so has part: feature:108652-114315:1:exon

NP_015093.1
type: Protein
SIO_000068: ncbiprotein

S000006152
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:108652-114315:1:exon

YPL230W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NSF1
gene: USV1
locus tag: YPL230W
gene synonym: NSF1
so part of: sequence
location: <115312..>116487
location: region:115312-116487:1
so has part: feature:115312-116487:1:exon
subclass of: SO_0000010

855871
type: Gene
SIO_000068: ncbigene

position:115312:1
position: 115312
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:116487:1
position: 116487
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:115312-116487:1:exon

YPL230W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NSF1
gene: USV1
locus tag: YPL230W
gene synonym: NSF1
product: Usv1p
transcript id: NM_001184044.1
SIO_010081: YPL230W
subclass of: SO_0000673
so part of: YPL230W
location: <115312..>116487
location: region:115312-116487:1
so has part: feature:115312-116487:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:115312-116487:1:exon

YPL230W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NSF1
gene: USV1
locus tag: YPL230W
gene synonym: NSF1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18667581|PMID:27663510]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363|PMID:19111667]
experiment: EXISTENCE:mutant phenotype:GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter [PMID:18667581]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:18667581]
note: Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis; USV1 has a paralog, RGM1, that arose from the whole genome duplication
codon start: 1
product: Usv1p
translation: MENTTNRNTAGVLTSSNGNFATNSVAASTPKRSKSARRKTFKCTGYDGCTMSFTRAEHLARHIRKHTGEKPFQCPACLKFFSRVDNLKQHRESVHAHKNHHSTSSHQRKPSSSSLSSSSSASSSSSASSSTSYSDPYRKTNINSGNMPMMAENEKAPQIIHSSPEFITSTRSIPPISPRSIYNTQRQQQHQQQQHQQAPYYFPSHPITDSYYQYPLPSNNNTINYLPSVDVQYPLNVSPSSTSHPASEVIISSFPPRSMPSTSFKYKDSADFQARTTMNKYNIRPSNINVNTSNINNHLDSFSPPFSPSTTVAEAKPIILPQYQQAFSQPPNGNKNNNMSSSKNGGKGGENFKNTDDRNDNNNKKRSETLSESDISVNTNKKRLSVDYILT
SIO_010081: YPL230W
subclass of: SO_0000673
so part of: YPL230W
location: 115312..116487
location: region:115312-116487:1
so has part: feature:115312-116487:1:exon

NP_015094.1
type: Protein
SIO_000068: ncbiprotein

S000006151
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:115312-116487:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1607; Autonomously Replicating Sequence
so part of: sequence
location: 116566..116680
location: region:116566-116680:1
so has part: feature:116566-116680:1:region

S000118413
type: SGD
SIO_000068: sgd

position:116566:1
position: 116566
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:116680:1
position: 116680
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:116566-116680:1:region

YPL229W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL229W
so part of: sequence
location: <117067..>117687
location: region:117067-117687:1
so has part: feature:117067-117687:1:exon
subclass of: SO_0000010

855872
type: Gene
SIO_000068: ncbigene

position:117067:1
position: 117067
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:117687:1
position: 117687
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117067-117687:1:exon

YPL229W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL229W
product: uncharacterized protein
transcript id: NM_001184043.1
SIO_010081: YPL229W
subclass of: SO_0000673
so part of: YPL229W
location: <117067..>117687
location: region:117067-117687:1
so has part: feature:117067-117687:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117067-117687:1:exon

YPL229W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL229W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; not an essential gene; YPL229W has a paralog, YMR181C, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MMPYNTPPNIQEPMNFASSNPFGIIPDALSFQNFKYDRLQQQQQQQQQQQQNRTASSLQQPQQQQPISPPLFLVGAGTSENSNLNKNANTSTIPPLLFSRSSQHYVVPDIDHSSIIYKNNICKSFKDDLFFCPRSLLSLEEQQACEKMDRLTAEQMSLYHQNTQSSSNPGSMSSSPPNSASSIFNSRPKFNPYTSQSFNPLESVQE
SIO_010081: YPL229W
subclass of: SO_0000673
so part of: YPL229W
location: 117067..117687
location: region:117067-117687:1
so has part: feature:117067-117687:1:exon

NP_015095.1
type: Protein
SIO_000068: ncbiprotein

S000006150
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117067-117687:1:exon

YPL228W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CES5
gene: CET1
locus tag: YPL228W
gene synonym: CES5
so part of: sequence
location: <118382..>120031
location: region:118382-120031:1
so has part: feature:118382-120031:1:exon
subclass of: SO_0000010

855873
type: Gene
SIO_000068: ncbigene

position:118382:1
position: 118382
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:120031:1
position: 120031
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:118382-120031:1:exon

YPL228W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CES5
gene: CET1
locus tag: YPL228W
gene synonym: CES5
product: polynucleotide 5'-phosphatase
transcript id: NM_001184042.1
SIO_010081: YPL228W
subclass of: SO_0000673
so part of: YPL228W
location: <118382..>120031
location: region:118382-120031:1
so has part: feature:118382-120031:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:118382-120031:1:exon

YPL228W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CES5
gene: CET1
locus tag: YPL228W
gene synonym: CES5
EC number: 3.6.1.74
experiment: EXISTENCE:direct assay:GO:0004651 polynucleotide 5'-phosphatase activity [PMID:9345280|PMID:17707331]
experiment: EXISTENCE:direct assay:GO:0098501 polynucleotide dephosphorylation [PMID:9345280]
experiment: EXISTENCE:genetic interaction:GO:0031533 mRNA cap methyltransferase complex [PMID:9710603]
experiment: EXISTENCE:mutant phenotype:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:24172134]
experiment: EXISTENCE:mutant phenotype:GO:1900182 positive regulation of protein localization to nucleus [PMID:24205062]
experiment: EXISTENCE:physical interaction:GO:0006370 7-methylguanosine mRNA capping [PMID:9345280]
experiment: EXISTENCE:physical interaction:GO:0031533 mRNA cap methyltransferase complex [PMID:9710603]
note: RNA 5'-triphosphatase involved in mRNA 5' capping; subunit of mRNA capping enzyme, which is a heterotetramer composed of a Cet1p homodimer and two molecules of guanylyltransferase Ceg1p; Cet1p also has a role in regulation of RNAPII pausing at promoter-proximal sites; interaction between Cet1p and Ceg1p is required for Ceg1p nuclear import; mammalian enzyme is single bifunctional polypeptide; human homolog RNGTT can complement yeast cet1 null mutant
codon start: 1
product: polynucleotide 5'-phosphatase
translation: MSYTDNPPQTKRALSLDDLVNHDENEKVKLQKLSEAANGSRPFAENLESDINQTETGQAAPIDNYKESTGHGSHSQKPKSRKSSNDDEETDTDDEMGASGEINFDSEMDFDYDKQHRNLLSNGSPPMNDGSDANAKLEKPSDDSIHQNSKSDEEQRIPKQGNEGNIASNYITQVPLQKQKQTEKKIAGNAVGSVVKKEEEANAAVDNIFEEKATLQSKKNNIKRDLEVLNEISASSKPSKYRNVPIWAQKWKPTIKALQSINVKDLKIDPSFLNIIPDDDLTKSVQDWVYATIYSIAPELRSFIELEMKFGVIIDAKGPDRVNPPVSSQCVFTELDAHLTPNIDASLFKELSKYIRGISEVTENTGKFSIIESQTRDSVYRVGLSTQRPRFLRMSTDIKTGRVGQFIEKRHVAQLLLYSPKDSYDVKISLNLELPVPDNDPPEKYKSQSPISERTKDRVSYIHNDSCTRIDITKVENHNQNSKSRQSETTHEVELEINTPALLNAFDNITNDSKEYASLIRTFLNNGTIIRRKLSSLSYEIFEGSKKVM
SIO_010081: YPL228W
subclass of: SO_0000673
so part of: YPL228W
location: 118382..120031
location: region:118382-120031:1
so has part: feature:118382-120031:1:exon

NP_015096.1
type: Protein
SIO_000068: ncbiprotein

S000006149
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:118382-120031:1:exon

YPL227C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALG5
locus tag: YPL227C
so part of: sequence
location: complement(<120163..>121167)
location: region:120163-121167:-1
so has part: feature:120163-121167:-1:exon
subclass of: SO_0000010

855874
type: Gene
SIO_000068: ncbigene

position:120163:-1
position: 120163
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:121167:-1
position: 121167
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:120163-121167:-1:exon

YPL227C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALG5
locus tag: YPL227C
product: dolichyl-phosphate beta-glucosyltransferase
transcript id: NM_001184041.1
SIO_010081: YPL227C
subclass of: SO_0000673
so part of: YPL227C
location: complement(<120163..>121167)
location: region:120163-121167:-1
so has part: feature:120163-121167:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:120163-121167:-1:exon

YPL227C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALG5
locus tag: YPL227C
EC number: 2.4.1.117
experiment: EXISTENCE:direct assay:GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity [PMID:8076653]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:9560251]
note: UDP-glucose:dolichyl-phosphate glucosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum; human ortholog ALG5 can partially complement yeast alg5 mutant
codon start: 1
product: dolichyl-phosphate beta-glucosyltransferase
translation: MRALRFLIENRNTVFFTLLVALVLSLYLLVYLFSHTPRPPYPEELKYIAIDEKGHEVSRALPNLNEHQDDEEIFLSVVIPSYNETGRILLMLTDAISFLKEKYGSRWEIVIVDDGSTDNTTQYCLKICKEQFKLNYEQFRIIKFSQNRGKGGAVRQGFLHIRGKYGLFADADGASKFSDVEKLIDAISKIETSSTDLKTTKPAVAIGSRAHMVNTEAVIKRSMIRNCLMYGFHTLVFIFGIRSIKDTQCGFKLFNRAAILKIFPYLHTEGWIFDVEILILAIRKRIQIEEIPISWHEVDGSKMALAIDSIKMAKDLVIIRMAYLLGIYRDNKKC
SIO_010081: YPL227C
subclass of: SO_0000673
so part of: YPL227C
location: complement(120163..121167)
location: region:120163-121167:-1
so has part: feature:120163-121167:-1:exon

NP_015097.1
type: Protein
SIO_000068: ncbiprotein

S000006148
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:120163-121167:-1:exon

YPL226W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NEW1
locus tag: YPL226W
so part of: sequence
location: <121767..>125357
location: region:121767-125357:1
so has part: feature:121767-125357:1:exon
subclass of: SO_0000010

855875
type: Gene
SIO_000068: ncbigene

position:121767:1
position: 121767
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:125357:1
position: 125357
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:121767-125357:1:exon

YPL226W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NEW1
locus tag: YPL226W
product: New1p
transcript id: NM_001184040.1
SIO_010081: YPL226W
subclass of: SO_0000673
so part of: YPL226W
location: <121767..>125357
location: region:121767-125357:1
so has part: feature:121767-125357:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:121767-125357:1:exon

YPL226W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NEW1
locus tag: YPL226W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:19806183]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:31299085]
experiment: EXISTENCE:mutant phenotype:GO:0006449 regulation of translational termination [PMID:31299085]
experiment: EXISTENCE:mutant phenotype:GO:0008079 translation termination factor activity [PMID:31299085]
experiment: EXISTENCE:mutant phenotype:GO:0042274 ribosomal small subunit biogenesis [PMID:19806183]
note: Translation termination and ribosome biogenesis factor; ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the small ribosomal subunit; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction
codon start: 1
product: New1p
translation: MPPKKFKDLNSFLDDQPKDPNLVASPFGGYFKNPAADAGSNNASKKSSYQQQRNWKQGGNYQQGGYQSYNSNYNNYNNYNNYNNYNNYNNYNKYNGQGYQKSTYKQSAVTPNQSGTPTPSASTTSLTSLNEKLSNLELTPISQFLSKIPECQSITDCKNQIKLIIEEFGKEGNSTGEKIEEWKIVDVLSKFIKPKNPSLVRESAMLIISNIAQFFSGKPPQEAYLLPFFNVALDCISDKENTVKRAAQHAIDSLLNCFPMEALTCFVLPTILDYLSSGAKWQAKMAALSVVDRIREDSANDLLELTFKDAVPVLTDVATDFKPELAKQGYKTLLDYVSILDNLDLSPRYKLIVDTLQDPSKVPESVKSLSSVTFVAEVTEPSLSLLVPILNRSLNLSSSSQEQLRQTVIVVENLTRLVNNRNEIESFIPLLLPGIQKVVDTASLPEVRELAEKALNVLKEDDEADKENKFSGRLTLEEGRDFLLDHLKDIKADDSCFVKPYMNDETVIKYMSKILTVDSNVNDWKRLEDFLTAVFGGSDSQREFVKQDFIHNLRALFYQEKERADEDEGIEIVNTDFSLAYGSRMLLNKTNLRLLKGHRYGLCGRNGAGKSTLMRAIANGQLDGFPDKDTLRTCFVEHKLQGEEGDLDLVSFIALDEELQSTSREEIAAALESVGFDEERRAQTVGSLSGGWKMKLELARAMLQKADILLLDEPTNHLDVSNVKWLEEYLLEHTDITSLIVSHDSGFLDTVCTDIIHYENKKLAYYKGNLAAFVEQKPEAKSYYTLTDSNAQMRFPPPGILTGVKSNTRAVAKMTDVTFSYPGAQKPSLSHVSCSLSLSSRVACLGPNGAGKSTLIKLLTGELVPNEGKVEKHPNLRIGYIAQHALQHVNEHKEKTANQYLQWRYQFGDDREVLLKESRKISEDEKEMMTKEIDIDDGRGKRAIEAIVGRQKLKKSFQYEVKWKYWKPKYNSWVPKDVLVEHGFEKLVQKFDDHEASREGLGYRELIPSVITKHFEDVGLDSEIANHTPLGSLSGGQLVKVVIAGAMWNNPHLLVLDEPTNYLDRDSLGALAVAIRDWSGGVVMISHNNEFVGALCPEQWIVENGKMVQKGSAQVDQSKFEDGGNADAVGLKASNLAKPSVDDDDSPANIKVKQRKKRLTRNEKKLQAERRRLRYIEWLSSPKGTPKPVDTDDEED
SIO_010081: YPL226W
subclass of: SO_0000673
so part of: YPL226W
location: 121767..125357
location: region:121767-125357:1
so has part: feature:121767-125357:1:exon

NP_015098.1
type: Protein
SIO_000068: ncbiprotein

S000006147
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:121767-125357:1:exon

YPL225W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL225W
so part of: sequence
location: <126006..>126446
location: region:126006-126446:1
so has part: feature:126006-126446:1:exon
subclass of: SO_0000010

855876
type: Gene
SIO_000068: ncbigene

position:126006:1
position: 126006
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:126446:1
position: 126446
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126006-126446:1:exon

YPL225W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL225W
product: uncharacterized protein
transcript id: NM_001184039.1
SIO_010081: YPL225W
subclass of: SO_0000673
so part of: YPL225W
location: <126006..>126446
location: region:126006-126446:1
so has part: feature:126006-126446:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126006-126446:1:exon

YPL225W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL225W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
note: hypothetical protein; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress
codon start: 1
product: uncharacterized protein
translation: MSTFNAETADNLEDIEKQFAVVAVEQAETYWKLLTSVPGSKLRLTKFDDEIYENFMERFPEYKDVERVKKFTEEELKTKEAKERWRKFFTIFEKKIEDYNFGTLLRTDASAEYGQFTTCFVVRLQFYAFEIARNKHGLNDWIVGQK
SIO_010081: YPL225W
subclass of: SO_0000673
so part of: YPL225W
location: 126006..126446
location: region:126006-126446:1
so has part: feature:126006-126446:1:exon

NP_015099.1
type: Protein
SIO_000068: ncbiprotein

S000006146
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126006-126446:1:exon

YPL224C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MFT2
gene: MMT2
locus tag: YPL224C
gene synonym: MFT2
so part of: sequence
location: complement(<126634..>128088)
location: region:126634-128088:-1
so has part: feature:126634-128088:-1:exon
subclass of: SO_0000010

855877
type: Gene
SIO_000068: ncbigene

position:126634:-1
position: 126634
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:128088:-1
position: 128088
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126634-128088:-1:exon

YPL224C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MFT2
gene: MMT2
locus tag: YPL224C
gene synonym: MFT2
product: Mmt2p
transcript id: NM_001184038.2
SIO_010081: YPL224C
subclass of: SO_0000673
so part of: YPL224C
location: complement(<126634..>128088)
location: region:126634-128088:-1
so has part: feature:126634-128088:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126634-128088:-1:exon

YPL224C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MFT2
gene: MMT2
locus tag: YPL224C
gene synonym: MFT2
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:9353309|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0006879 cellular iron ion homeostasis [PMID:9353309]
experiment: EXISTENCE:mutant phenotype:GO:0006879 cellular iron ion homeostasis [PMID:9353309]
note: Putative metal transporter involved in mitochondrial iron accumulation; MMT2 has a paralog, MMT1, that arose from the whole genome duplication
codon start: 1
product: Mmt2p
translation: MLRISIDSIKQFGSFVPGYNNTSYHAAGRAIRTSSLYSTMISANPRRCLHSSKLLNKEGQEEGYNEQLISKMSSQNGSNSRQNESEGKKEGKASSVKSLLQHTHSHSHTHMHDNPLLSLNVQQIKKNPGVRITWIGLASNVGMAVGKFVGGITFHSQALLADSVHALSDLVSDFLTLFSVQYASRKPTSEYPYGYGKVETVGSLAVSTILAMAGISIGWSSLCAIVGPVIPHAILESMAGLIGETHSHSQSLTQQATNVNAVWIAAGSILVKEWVFQATKKVAIQTNSNVLMANAWHHRVDSLTSLVALVAITSSYFFNIQSLDNLGGLVVSGLIIKTGGQGILSSLKELVDQSIPPTDPRYLEIESVIKDSIGSLKTDLDLKQSLHVRDLTILASGPNLRATTTLEVPVLHSGQEVGIRFLENAISTIREDLRMKVPNVGKVDVEFVDVTSDSKGDLEHSHDTKSTNHTHTHSDSADTHTHKH
SIO_010081: YPL224C
subclass of: SO_0000673
so part of: YPL224C
location: complement(126634..128088)
location: region:126634-128088:-1
so has part: feature:126634-128088:-1:exon

NP_015100.2
type: Protein
SIO_000068: ncbiprotein

S000006145
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126634-128088:-1:exon

YPL223C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GRE1
locus tag: YPL223C
so part of: sequence
location: complement(<128632..>129138)
location: region:128632-129138:-1
so has part: feature:128632-129138:-1:exon
subclass of: SO_0000010

855878
type: Gene
SIO_000068: ncbigene

position:128632:-1
position: 128632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:129138:-1
position: 129138
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:128632-129138:-1:exon

YPL223C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GRE1
locus tag: YPL223C
product: Gre1p
transcript id: NM_001184037.1
SIO_010081: YPL223C
subclass of: SO_0000673
so part of: YPL223C
location: complement(<128632..>129138)
location: region:128632-129138:-1
so has part: feature:128632-129138:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:128632-129138:-1:exon

YPL223C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GRE1
locus tag: YPL223C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
note: Hydrophilin essential in desiccation-rehydration process; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway; GRE1 has a paralog, SIP18, that arose from the whole genome duplication
codon start: 1
product: Gre1p
translation: MSNLLNKFADKLHGNDHDERYEDDNDDQTRQQRHEKHQQREFRNQGSKADPYGEENQGNFPQRQQPQSNLGGNTQFGGNDFQQQTTDYTAGTGGGTYTQTYRETNTQGQLDDDEDDDFLTSGQQQKQGRTRGAQSNRYQSSNIGSGRRDLSGSGNDEYDDDSGNQGVW
SIO_010081: YPL223C
subclass of: SO_0000673
so part of: YPL223C
location: complement(128632..129138)
location: region:128632-129138:-1
so has part: feature:128632-129138:-1:exon

NP_015101.1
type: Protein
SIO_000068: ncbiprotein

S000006144
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:128632-129138:-1:exon

YPL222W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMP40
locus tag: YPL222W
so part of: sequence
location: <130162..>132228
location: region:130162-132228:1
so has part: feature:130162-132228:1:exon
subclass of: SO_0000010

855879
type: Gene
SIO_000068: ncbigene

position:130162:1
position: 130162
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:132228:1
position: 132228
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:130162-132228:1:exon

YPL222W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMP40
locus tag: YPL222W
product: Fmp40p
transcript id: NM_001184036.1
SIO_010081: YPL222W
subclass of: SO_0000673
so part of: YPL222W
location: <130162..>132228
location: region:130162-132228:1
so has part: feature:130162-132228:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:130162-132228:1:exon

YPL222W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMP40
locus tag: YPL222W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:30270044|P MID:24769239]
experiment: EXISTENCE:direct assay:GO:0018117 protein adenylylation [PMID:30270044]
experiment: EXISTENCE:direct assay:GO:0045454 cell redox homeostasis [PMID:30270044]
experiment: EXISTENCE:direct assay:GO:0070733 protein adenylyltransferase activity [PMID:30270044]
note: Mitochondrial AMPylator in the pseudokinase selenoprotein-O family; role in the oxidative stress response, transferring AMP from ATP to protein substrates (AMPylation) involved in redox homeostasis; regulates S-glutathionylation levels; proposed involvement in the environmental stress response
codon start: 1
product: Fmp40p
translation: MGEKRTIIKALKNSAASHFIKKLTADTSLSSIQEAINVVQQYNATDPVRLKLFHTPRMVSQGAHFAFCLPTKKPHYKPLLLSQNALDEFNLVQDQDLEKILSGEKVYYSDSIFPYSTVYSGFQFGSFAAQLGDGRVVNLFDLKDKCSGQWQTFQLKGAGMTPFSRFADGKAVLRSSIREFIMSEALHSIGIPSTRAMQLTLLPGTKAQRRNQEPCAVVCRFAPSWIRLGNFNLFRWRHDLKGLIQLSDYCIEELFAGGTQFEGKPDFNIFKRDFFPDTETKIDEQVEKDETEVSTMTGDNISTLSKYDEFFRHVVSLNANTVAHWQAYGFANGVLNTDNTSIMGLTIDYGPFAFLDKFEPSFTPNHDDTAKRYSFANQPSIIWWNLQQFAKDLACLLGPEARDLELLLKGELNSVDDALEKTMIERVQKLVELSANEYKYVFTTRYAQIMSQRLGVDLDLEKCMSSTNLKDIEHAAEKAKEFCDVIVEPLLDILQATKVDYNNFFIHLQNYKGPFFIKDKSDTATLFGAFDEEYLGMFFNSKQLQQMAETEEAFAAGEKVFDANGELRLLNEKLQEIRNWTQDYLTLVPPTETAARASLAKKANPLFVPRSWVLEEVVDDLMYSQRDGLQDPSSELDTSALKKLYLMSVNPYDRTKWDVTLRPELETKWADLSHQDDAKFMMQASCSS
SIO_010081: YPL222W
subclass of: SO_0000673
so part of: YPL222W
location: 130162..132228
location: region:130162-132228:1
so has part: feature:130162-132228:1:exon

NP_015102.1
type: Protein
SIO_000068: ncbiprotein

S000006143
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:130162-132228:1:exon

YPL221W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FLC1
locus tag: YPL221W
so part of: sequence
location: <133043..>135424
location: region:133043-135424:1
so has part: feature:133043-135424:1:exon
subclass of: SO_0000010

855880
type: Gene
SIO_000068: ncbigene

position:133043:1
position: 133043
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:135424:1
position: 135424
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:133043-135424:1:exon

YPL221W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FLC1
locus tag: YPL221W
product: flavin adenine dinucleotide transporter
transcript id: NM_001184035.1
SIO_010081: YPL221W
subclass of: SO_0000673
so part of: YPL221W
location: <133043..>135424
location: region:133043-135424:1
so has part: feature:133043-135424:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:133043-135424:1:exon

YPL221W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FLC1
locus tag: YPL221W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:16717099]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0030148 sphingolipid biosynthetic process [PMID:27462707]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0009272 fungal-type cell wall biogenesis [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0015230 FAD transmembrane transporter activity [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0015883 FAD transport [PMID:16717099]
note: Flavin adenine dinucleotide transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC1 has a paralog, FLC3, that arose from the whole genome duplication
codon start: 1
product: flavin adenine dinucleotide transporter
translation: MQVLVTLWCLICTCLVLPVAAKKRTLTASSLVTCMENSQLSANSFDVSFSPDDRSLHYDLDMTTQIDSYIYAYVDVYAYGFKIITENFDVCSMGWKQFCPVHPGNIQIDSIEYIAQKYVKMIPGIAYQVPDIDAYVRLNIYNNVSENLACIQVFFSNGKTVSQIGVKWVTAVIAGIGLLTSAVLSTFGNSTAASHISANTMSLFLYFQSVAVVAMQHVDSVPPIAAAWSENLAWSMGLIRITFMQKIFRWYVEATGGSASLYLTATTMSVLTQRGLDYLKNTSVYKRAENVLYGNSNTLIFRGIKRMGYRMKIENTAIVCTGFTFFVLCGYFLAGFIMACKYSIELCIRCGWMRSDRFYQFRKNWRSVLKGSLLRYIYIGFTQLTILSFWEFTERDSAGVIVIACLFIVLSCGLMAWAAYRTIFFASKSVEMYNNPAALLYGDEYVLNKYGFFYTMFNAKHYWWNALLTTYILVKALFVGFAQASGKTQALAIFIIDLAYFVAIIRYKPYLDRPTNIVNIFICTVTLVNSFLFMFFSNLFNQKYAVSAIMGWVFFIMNAAFSLLLLLMILAFTTIILFSKNPDSRFKPAKDDRASFQKHAIPHEGALNKSVANELMALGNVAKDHTENWEYELKSQEGKSEDNLFGVEYDDEKTGTNSENAESSSKETTRPTFSEKVLRSLSIKRNKSKLGSFKRSAPDKITQQEVSPDRASSSPNSKSYPGVSHTRQESEANNGLINAYEDEQFSLMEPSILEDAASSTQMHAMPARDLSLSSVANAQDVTKKANILDPDYL
SIO_010081: YPL221W
subclass of: SO_0000673
so part of: YPL221W
location: 133043..135424
location: region:133043-135424:1
so has part: feature:133043-135424:1:exon

NP_015103.1
type: Protein
SIO_000068: ncbiprotein

S000006142
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:133043-135424:1:exon

YPL220W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PUB2
alternative label: SSM1
gene: RPL1A
locus tag: YPL220W
gene synonym: PUB2; SSM1
so part of: sequence
location: <135790..>136443
location: region:135790-136443:1
so has part: feature:135790-136443:1:exon
subclass of: SO_0000010

855881
type: Gene
SIO_000068: ncbigene

position:135790:1
position: 135790
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136443:1
position: 136443
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:135790-136443:1:exon

YPL220W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PUB2
alternative label: SSM1
gene: RPL1A
locus tag: YPL220W
gene synonym: PUB2; SSM1
product: ribosomal 60S subunit protein L1A
transcript id: NM_001184034.1
SIO_010081: YPL220W
subclass of: SO_0000673
so part of: YPL220W
location: <135790..>136443
location: region:135790-136443:1
so has part: feature:135790-136443:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:135790-136443:1:exon

YPL220W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PUB2
alternative label: SSM1
gene: RPL1A
locus tag: YPL220W
gene synonym: PUB2; SSM1
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:31439809]
note: Ribosomal 60S subunit protein L1A; N-terminally acetylated; homologous to mammalian ribosomal protein L10A and bacterial L1; RPL1A has a paralog, RPL1B, that arose from the whole genome duplication; rpl1a rpl1b double null mutation is lethal; ribosomes containing Rpl1b are more efficient in translation of respiration-related proteins
codon start: 1
product: ribosomal 60S subunit protein L1A
translation: MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
SIO_010081: YPL220W
subclass of: SO_0000673
so part of: YPL220W
location: 135790..136443
location: region:135790-136443:1
so has part: feature:135790-136443:1:exon

NP_015104.1
type: Protein
SIO_000068: ncbiprotein

S000006141
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:135790-136443:1:exon

YPL219W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PCL8
locus tag: YPL219W
so part of: sequence
location: <136750..>138228
location: region:136750-138228:1
so has part: feature:136750-138228:1:exon
subclass of: SO_0000010

855882
type: Gene
SIO_000068: ncbigene

position:136750:1
position: 136750
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:138228:1
position: 138228
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136750-138228:1:exon

YPL219W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PCL8
locus tag: YPL219W
product: Pcl8p
transcript id: NM_001184033.1
SIO_010081: YPL219W
subclass of: SO_0000673
so part of: YPL219W
location: <136750..>138228
location: region:136750-138228:1
so has part: feature:136750-138228:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:136750-138228:1:exon

YPL219W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PCL8
locus tag: YPL219W
experiment: EXISTENCE:genetic interaction:GO:0045719 negative regulation of glycogen biosynthetic process [PMID:9584169]
experiment: EXISTENCE:mutant phenotype:GO:0045719 negative regulation of glycogen biosynthetic process [PMID:9584169]
note: Cyclin; interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation; PCL8 has a paralog, PCL10, that arose from the whole genome duplication
codon start: 1
product: Pcl8p
translation: MANDQDPNKSLINDALTRSMSEFYDDDDDNDSDMCRANDEGEDVFDLPLKVGVSQSRNFSEVNDVLDPLSSLHGPSKKVRFEQQKQQQQHQQLHNDFNTDFNLKSPSSKKMGVEQLIQSANEINDYLANNIDKVNSFNSELLSGSGKLPGRVKSDTATQGTGRLDSMSNFALSDTELDNDDDNYLLDPLANASSTTPTVEHHGYSLLDKALSTSDKEKIYTNKVNSNSQIDTDNHSHESGNTTNNETDENESSEILDYTKFDSFPYPPSSAPNGEPPDLKVLSIECEQENEKELRRISLLLDHYESIPKIPELSDDEALSKFRENIELILQLSKKINDNANTLAISSEDPQKFVNFVMKNPPSLSFRDFIDRIQNKCMFGAVVYLGATYLLQLVFLTRDEMDGPIKLKAKLQEDQAHRIIISTIRIATKLLEDFVHSQNYICKVFGISKRLLTKLEISFMASVNFDGLMITCEKLEKTLHILDDTRQALGNT
SIO_010081: YPL219W
subclass of: SO_0000673
so part of: YPL219W
location: 136750..138228
location: region:136750-138228:1
so has part: feature:136750-138228:1:exon

NP_015105.1
type: Protein
SIO_000068: ncbiprotein

S000006140
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:136750-138228:1:exon

YPL218W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAR1
locus tag: YPL218W
so part of: sequence
location: <138698..>139409
location: region:138698-139409:1
so has part: feature:138698-139409:1:exon
subclass of: SO_0000010

855883
type: Gene
SIO_000068: ncbigene

position:138698:1
position: 138698
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:139409:1
position: 139409
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:138698-139409:1:exon

YPL218W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAR1
locus tag: YPL218W
product: Arf family GTPase SAR1
transcript id: NM_001184032.1
SIO_010081: YPL218W
subclass of: SO_0000673
so part of: YPL218W
location: join(<138698..138725,138865..>139409)
location: region:138698-139409:1
so has part: feature:138698-138725:1:exon
so has part: feature:138865-139409:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:138698-138725:1:exon

position:138725:1
position: 138725
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:138865-139409:1:exon

position:138865:1
position: 138865
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL218W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAR1
locus tag: YPL218W
experiment: EXISTENCE:direct assay:GO:0003400 regulation of COPII vesicle coating [PMID:14627716|PMID:15665868]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:8419365|PMID:9756629]
experiment: EXISTENCE:direct assay:GO:0016050 vesicle organization [PMID:16122427]
experiment: EXISTENCE:direct assay:GO:0030127 COPII vesicle coat [PMID:8004676]
experiment: EXISTENCE:direct assay:GO:0044233 mitochondria-associated endoplasmic reticulum membrane [PMID:27101143]
experiment: EXISTENCE:direct assay:GO:0070971 endoplasmic reticulum exit site [PMID:22675024]
experiment: EXISTENCE:genetic interaction:GO:0000266 mitochondrial fission [PMID:27101143]
experiment: EXISTENCE:mutant phenotype:GO:0006998 nuclear envelope organization [PMID:31406088]
experiment: EXISTENCE:mutant phenotype:GO:0007006 mitochondrial membrane organization [PMID:27101143]
experiment: EXISTENCE:mutant phenotype:GO:0061024 membrane organization [PMID:27101143]
note: ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics
codon start: 1
product: Arf family GTPase SAR1
translation: MAGWDIFGWFRDVLASLGLWNKHGKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELAIGNIKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAADPERFDEARVELDALFNIAELKDVPFVILGNKIDAPNAVSEAELRSALGLLNTTGSQRIEGQRPVEVFMCSVVMRNGYLEAFQWLSQYI
SIO_010081: YPL218W
subclass of: SO_0000673
so part of: YPL218W
location: join(138698..138725,138865..139409)
location: region:138698-139409:1
so has part: feature:138698-138725:1:exon
so has part: feature:138865-139409:1:exon

NP_015106.1
type: Protein
SIO_000068: ncbiprotein

S000006139
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:138698-138725:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:138865-139409:1:exon

YPL217C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BMS1
locus tag: YPL217C
so part of: sequence
location: complement(<139620..>143171)
location: region:139620-143171:-1
so has part: feature:139620-143171:-1:exon
subclass of: SO_0000010

855884
type: Gene
SIO_000068: ncbigene

position:139620:-1
position: 139620
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:143171:-1
position: 143171
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139620-143171:-1:exon

YPL217C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BMS1
locus tag: YPL217C
product: GTPase BMS1
transcript id: NM_001184031.1
SIO_010081: YPL217C
subclass of: SO_0000673
so part of: YPL217C
location: complement(<139620..>143171)
location: region:139620-143171:-1
so has part: feature:139620-143171:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:139620-143171:-1:exon

YPL217C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BMS1
locus tag: YPL217C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:16307926]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:16307926]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11565749|PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:16307926|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0034511 U3 snoRNA binding [PMID:16307926]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11565749]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11565749]
experiment: EXISTENCE:mutant phenotype:GO:0003924 GTPase activity [PMID:16307926]
experiment: EXISTENCE:mutant phenotype:GO:0005525 GTP binding [PMID:11565749|PMID:16307926]
note: GTPase required for ribosomal subunit synthesis and rRNA processing; required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, which stimulates its GTPase and U3 snoRNA binding activities; has similarity to Tsr1p
codon start: 1
product: GTPase BMS1
translation: MEQSNKQHRKAKEKNTAKKKLHTQGHNAKAFAVAAPGKMARTMQRSSDVNERKLHVPMVDRTPEDDPPPFIVAVVGPPGTGKTTLIRSLVRRMTKSTLNDIQGPITVVSGKHRRLTFLECPADDLNAMIDIAKIADLVLLLIDGNFGFEMETMEFLNIAQHHGMPRVLGVATHLDLFKSQSTLRASKKRLKHRFWTEVYQGAKLFYLSGVINGRYPDREILNLSRFISVMKFRPLKWRNEHPYMLADRFTDLTHPELIETQGLQIDRKVAIYGYLHGTPLPSAPGTRVHIAGVGDFSVAQIEKLPDPCPTPFYQQKLDDFEREKMKEEAKANGEITTASTTRRRKRLDDKDKLIYAPMSDVGGVLMDKDAVYIDIGKKNEEPSFVPGQERGEGEKLMTGLQSVEQSIAEKFDGVGLQLFSNGTELHEVADHEGMDVESGEESIEDDEGKSKGRTSLRKPRIYGKPVQEEDADIDNLPSDEEPYTNDDDVQDSEPRMVEIDFNNTGEQGAEKLALETDSEFEESEDEFSWERTAANKLKKTESKKRTWNIGKLIYMDNISPEECIRRWRGEDDDSKDESDIEEDVDDDFFRKKDGTVTKEGNKDHAVDLEKFVPYFDTFEKLAKKWKSVDAIKERFLGAGILGNDNKTKSDSNEGGEELYGDFEDLEDGNPSEQAEDNSDKESEDEDENEDTNGDDDNSFTNFDAEEKKDLTMEQEREMNAAKKEKLRAQFEIEEGENFKEDDENNEYDTWYELQKAKISKQLEINNIEYQEMTPEQRQRIEGFKAGSYVRIVFEKVPMEFVKNFNPKFPIVMGGLLPTEIKFGIVKARLRRHRWHKKILKTNDPLVLSLGWRRFQTLPIYTTTDSRTRTRMLKYTPEHTYCNAAFYGPLCSPNTPFCGVQIVANSDTGNGFRIAATGIVEEIDVNIEIVKKLKLVGFPYKIFKNTAFIKDMFSSAMEVARFEGAQIKTVSGIRGEIKRALSKPEGHYRAAFEDKILMSDIVILRSWYPVRVKKFYNPVTSLLLKEKTEWKGLRLTGQIRAAMNLETPSNPDSAYHKIERVERHFNGLKVPKAVQKELPFKSQIHQMKPQKKKTYMAKRAVVLGGDEKKARSFIQKVLTISKAKDSKRKEQKASQRKERLKKLAKMEEEKSQRDKEKKKEYFAQNGKRTTMGGDDESRPRKMRR
SIO_010081: YPL217C
subclass of: SO_0000673
so part of: YPL217C
location: complement(139620..143171)
location: region:139620-143171:-1
so has part: feature:139620-143171:-1:exon

NP_015107.1
type: Protein
SIO_000068: ncbiprotein

S000006138
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139620-143171:-1:exon

YPL216W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL216W
so part of: sequence
location: <143821..>147129
location: region:143821-147129:1
so has part: feature:143821-147129:1:exon
subclass of: SO_0000010

855885
type: Gene
SIO_000068: ncbigene

position:143821:1
position: 143821
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:147129:1
position: 147129
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143821-147129:1:exon

YPL216W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL216W
product: uncharacterized protein
transcript id: NM_001184030.1
SIO_010081: YPL216W
subclass of: SO_0000673
so part of: YPL216W
location: <143821..>147129
location: region:143821-147129:1
so has part: feature:143821-147129:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143821-147129:1:exon

YPL216W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL216W
note: hypothetical protein; not an essential gene; YPL216W has a paralog, ITC1, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MVLLNRRKIQPKEIGQSADSFSETPWVIKESSERINDYDSDLKKLDFYKRDIFTCEISGKDGLSYFKALKSEEQHREKVRYLLPKELRKAIANFANFSPIRKVGHLVESAFQRFSNRFFIGDTVCLKTIQKNALITYKEGEPNLVESPTIENNVTLFLVKDVFQSNGMMESEKGEISAPKLSLYLITECLNRESKGAALIVGQNEIKRPESHFSKFIIACFLNEILIKVSNKEHAPWRVKQEYIERYDVNPKCSPNMIDYLPDRMNSSSSELYTPLTIPPESDVEPADWKETSETSETSETSLSKIKAIDDEISVSFDHIYDNVNSLAYNDLKGTVDDKELPFTGPSIPFENISYLDSSLEYKNIDQKWFKECSQFPTERLLVVYQFLSFFGRFIGLSHFNFDQFLTTIKCTSPEALVDEYVKINFLKTYNSKGSFTNEKPRNEIYNQVTSSNVSQREKANVFNADESQRIPSNFTRNQKMRKFITDKSTEFVMYSIFKGKPLKNDDMEFQSYEKVNILYIDIVCSLMCLMTDNEPDWNCNLMDNWTEEKRKEEGNKTEIDIAIEKCLNYGDTSWVKLLHNKNFSNGNWLICLLGILQQNTHMIAYSDVAKCITKKILPLSMNFVNLGDELWDNFRKRLSIKDKIDVLWVLVDFASNFSSYIKELVDKVPKLCNGIRLKLDSAKKEYIKLKRQLKTLTKNRVKLHSNVSMNRYGSDECKGKVNALKVKIAYLMEDIAFLEAKLIQSDIKRLEILGKDRNGNRYYWMDSNGSSSAISEKNEELYNCCFLWVQGPSEADINFCLDVDVESLKKWELLAKAKGTAYATKEVFSIFRSTDGSYYQIAQGENFMIINSNGILMRPTIPAFIDKKIISETPEKLLLSHHQWAFFNDIEDIHMLVDRLDDLRENEGQLKKALTSKMDRIEVSYKQQFKIKRRIECDETFKKNHKLLKNNEFTFPELKRIETTCTSNGQHFSNMEKISKKLSRTKNDLVLEAILKDVAHLGECERALLKKQQNLIYPLNFHFEQLRTIDLEFIVETKRKRQEDILTKLLNHQRYKHISHVSGYGISSQRVDKAAHLDVQGILEEIECQLISRRREDEERN
SIO_010081: YPL216W
subclass of: SO_0000673
so part of: YPL216W
location: 143821..147129
location: region:143821-147129:1
so has part: feature:143821-147129:1:exon

NP_015108.1
type: Protein
SIO_000068: ncbiprotein

S000006137
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143821-147129:1:exon

YPL215W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CBP3
locus tag: YPL215W
so part of: sequence
location: <147416..>148423
location: region:147416-148423:1
so has part: feature:147416-148423:1:exon
subclass of: SO_0000010

855886
type: Gene
SIO_000068: ncbigene

position:147416:1
position: 147416
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:148423:1
position: 148423
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147416-148423:1:exon

YPL215W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CBP3
locus tag: YPL215W
product: Cbp3p
transcript id: NM_001184029.1
SIO_010081: YPL215W
subclass of: SO_0000673
so part of: YPL215W
location: <147416..>148423
location: region:147416-148423:1
so has part: feature:147416-148423:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147416-148423:1:exon

YPL215W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CBP3
locus tag: YPL215W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:23509072]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:29475949]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11522252|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005761 mitochondrial ribosome [PMID:21670217]
experiment: EXISTENCE:direct assay:GO:0031966 mitochondrial membrane [PMID:11522252]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:21670217]
experiment: EXISTENCE:mutant phenotype:GO:0034551 mitochondrial respiratory chain complex III assembly [PMID:11522252|PMID:15759116]
experiment: EXISTENCE:mutant phenotype:GO:0070131 positive regulation of mitochondrial translation [PMID:21670217]
experiment: EXISTENCE:physical interaction:GO:0043022 ribosome binding [PMID:21670217]
experiment: EXISTENCE:physical interaction:GO:0061671 Cbp3p-Cbp6 complex [PMID:21670217]
note: Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation
codon start: 1
product: Cbp3p
translation: MMSVNRFTSGRLPVFLRKSPFYYSRAYLHQTCVFKQNKETAQDSPELLAKSSHLNSKPLDVSNKAPVKTAQNKIPLAHSKYESSKYELPKWKEALGELVIRAFHLDMDRVRAGPVAGSYYYKICKEQGLQYEDEPLSETAKYFYEDLKLPRTFSQWFQITVLHEWILFVRMRAMPFKYGRNYQQKLVDRTFSDIELRLFEEMKVNSGRIADQYLKDFNTQLRGAIFAYDEGFATDDGTLATAVWRNLFGGRKNIDMVHLESVVRYIYSQLYVLSRLSDREFATGKFKFVPPGVKVEKLTPKQEEELKAKTIAKYEALDKDPKTLPSERSRLSYTN
SIO_010081: YPL215W
subclass of: SO_0000673
so part of: YPL215W
location: 147416..148423
location: region:147416-148423:1
so has part: feature:147416-148423:1:exon

NP_015109.1
type: Protein
SIO_000068: ncbiprotein

S000006136
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147416-148423:1:exon

YPL214C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THI6
locus tag: YPL214C
so part of: sequence
location: complement(<148569..>150191)
location: region:148569-150191:-1
so has part: feature:148569-150191:-1:exon
subclass of: SO_0000010

855887
type: Gene
SIO_000068: ncbigene

position:148569:-1
position: 148569
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:150191:-1
position: 150191
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148569-150191:-1:exon

YPL214C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THI6
locus tag: YPL214C
product: bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase
transcript id: NM_001184028.1
SIO_010081: YPL214C
subclass of: SO_0000673
so part of: YPL214C
location: complement(<148569..>150191)
location: region:148569-150191:-1
so has part: feature:148569-150191:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:148569-150191:-1:exon

YPL214C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THI6
locus tag: YPL214C
EC number: 2.5.1.3
EC number: 2.7.1.50
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:16850348]
experiment: EXISTENCE:mutant phenotype:GO:0004417 hydroxyethylthiazole kinase activity [PMID:7982968]
experiment: EXISTENCE:mutant phenotype:GO:0004789 thiamine-phosphate diphosphorylase activity [PMID:7982968]
experiment: EXISTENCE:mutant phenotype:GO:0009228 thiamine biosynthetic process [PMID:7982968]
note: Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
codon start: 1
product: bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase
translation: MVFTKEEVDYSLYLVTDSTMLPPGTTLCSQVEAGLKNGVTLVQIREKDIETKNFVAEALEVQKICKKYNVPLIINDRIDVAMAIDADGVHVGQDDMPIPMVRKLLGPSKILGWSVGKPSEVETLAKWGPDMVDYIGVGTLFPTSTKKNPKKSPMGPQGAIAILDALEEFKATWCRTVGIGGLHPDNIQRVLCQCVASNGKRSLDGISLVSDIMAAPDACAATKRLRGLLDATRYQFVECELNNTFPTTTSIQNVISQVSNNRPLVQHITNKVHQNFGANVTLALGSSPIMSEIESEVSELARIPNASLLLNTGSVAPIEMLKAAINAYNEVNRPITFDPVGYSATETRLCLNNTLLTYGQFACIKGNCSEILSLAKLNNHKMKGVDSSSGKTNIDTLVRATQIVAFQYRTVAVCTGEFDCVADGTFGGEYKLSSGTEGITAEDLPCVIIEDGPIPIMGDITASGCSLGSTIASFIGGLDSTGKLFDAVVGAVLLYKSAGKLASTRCQGSGSFHVELIDALYQLFHENKPEKWSASLKKFK
SIO_010081: YPL214C
subclass of: SO_0000673
so part of: YPL214C
location: complement(148569..150191)
location: region:148569-150191:-1
so has part: feature:148569-150191:-1:exon

NP_015110.1
type: Protein
SIO_000068: ncbiprotein

S000006135
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:148569-150191:-1:exon

YPL213W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LEA1
locus tag: YPL213W
so part of: sequence
location: <150614..>151330
location: region:150614-151330:1
so has part: feature:150614-151330:1:exon
subclass of: SO_0000010

855888
type: Gene
SIO_000068: ncbigene

position:150614:1
position: 150614
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:151330:1
position: 151330
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150614-151330:1:exon

YPL213W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LEA1
locus tag: YPL213W
product: U2 snRNP complex subunit LEA1
transcript id: NM_001184027.1
SIO_010081: YPL213W
subclass of: SO_0000673
so part of: YPL213W
location: <150614..>151330
location: region:150614-151330:1
so has part: feature:150614-151330:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:150614-151330:1:exon

YPL213W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LEA1
locus tag: YPL213W
experiment: EXISTENCE:direct assay:GO:0005686 U2 snRNP [PMID:9799242]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:9799242]
experiment: EXISTENCE:physical interaction:GO:0005686 U2 snRNP [PMID:9799242]
note: Component of U2 snRNP complex; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; putative homolog of human U2A' snRNP protein
codon start: 1
product: U2 snRNP complex subunit LEA1
translation: MKFTPSIVIDAPQYYVDHFNGKYNVDKCVILRDLQLETDSESMPSSLKHLTKPTHILDLTNNDLIMIPDLSRRDDIHTLLLGRNNIVEVDGRLLPMNVQNLTLSNNSIRRFEDLQRLRRAPRTLKNLTLIGNQVCHLANYREHVLRLVPHLETLDFQNVTAEERKSAMSFPRQADGDTLGPVNTAIRDNGSRDKTMEIMNLVVSKMTVERRNELKKQLAEATSLEEIARLEKLLSGGV
SIO_010081: YPL213W
subclass of: SO_0000673
so part of: YPL213W
location: 150614..151330
location: region:150614-151330:1
so has part: feature:150614-151330:1:exon

NP_015111.1
type: Protein
SIO_000068: ncbiprotein

S000006134
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:150614-151330:1:exon

YPL212C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PUS1
locus tag: YPL212C
so part of: sequence
location: complement(<151515..>153149)
location: region:151515-153149:-1
so has part: feature:151515-153149:-1:exon
subclass of: SO_0000010

855889
type: Gene
SIO_000068: ncbigene

position:151515:-1
position: 151515
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:153149:-1
position: 153149
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151515-153149:-1:exon

YPL212C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PUS1
locus tag: YPL212C
product: pseudouridine synthase PUS1
transcript id: NM_001184026.1
SIO_010081: YPL212C
subclass of: SO_0000673
so part of: YPL212C
location: complement(<151515..>153149)
location: region:151515-153149:-1
so has part: feature:151515-153149:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:151515-153149:-1:exon

YPL212C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PUS1
locus tag: YPL212C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8641292]
experiment: EXISTENCE:direct assay:GO:0009982 pseudouridine synthase activity [PMID:10356324]
experiment: EXISTENCE:direct assay:GO:0031119 tRNA pseudouridine synthesis [PMID:10356324]
experiment: EXISTENCE:mutant phenotype:GO:0031120 snRNA pseudouridine synthesis [PMID:10022901]
experiment: EXISTENCE:mutant phenotype:GO:1990481 mRNA pseudouridine synthesis [PMID:25192136|PMID:25219674]
note: tRNA:pseudouridine synthase; introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; also acts on U2 snRNA; also pseudouridylates some mRNAs, and pseudouridylation level varies with growth phase; nuclear protein that appears to be involved in tRNA export; PUS1 has a paralog, PUS2, that arose from the whole genome duplication
codon start: 1
product: pseudouridine synthase PUS1
translation: MSEENLRPAYDDQVNEDVYKRGAQSKLTKARKADFDDEKDKKKDNDKHIDKRPKSGPRLDENGNPLPKEPRLPKRKVAVMVGYCGTGYHGMQYNPPNPTIESALFKAFVEAGAISKDNSNDLKKNGFMRAARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWYEYLLPTYSLIGPKPGSILYRDIEESKTELPGVLDEDLESKEFWEEFKKDANEKFSTEEIEAILAYVPPARDEFDINEELYQKVKKYKQLENAHRRRYRISAAKLAKFRASTSQYLGAHNFHNFTLGKDFKEPSAIRFMKDIKVSDPFVIGDAQTEWISIKIHGQSFMLHQIRKMVSMATLITRCGCPVERISQAYGQQKINIPKAPALGLLLEAPVFEGYNKRLEQFGYKAIDFSKYQDEVDKFKMKHIYDKIYKEEVDENVFNAFFSYIDSFNKVTGAQGEETADKSGPAVQKSIFEFLTAKGIPGLTDAPESNKKIKQRKRMEEEEAASKKAEISSTTQSNEPEVQPEAAAN
SIO_010081: YPL212C
subclass of: SO_0000673
so part of: YPL212C
location: complement(151515..153149)
location: region:151515-153149:-1
so has part: feature:151515-153149:-1:exon

NP_015112.1
type: Protein
SIO_000068: ncbiprotein

S000006133
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151515-153149:-1:exon

YPL211W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NIP7
locus tag: YPL211W
so part of: sequence
location: <153495..>154040
location: region:153495-154040:1
so has part: feature:153495-154040:1:exon
subclass of: SO_0000010

855890
type: Gene
SIO_000068: ncbigene

position:153495:1
position: 153495
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154040:1
position: 154040
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:153495-154040:1:exon

YPL211W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NIP7
locus tag: YPL211W
product: ribosome biosynthesis protein NIP7
transcript id: NM_001184025.1
SIO_010081: YPL211W
subclass of: SO_0000673
so part of: YPL211W
location: <153495..>154040
location: region:153495-154040:1
so has part: feature:153495-154040:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:153495-154040:1:exon

YPL211W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NIP7
locus tag: YPL211W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9271378|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9271378]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614|PMID:17443350|PMID:23212245]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:9271378]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:9271378]
experiment: EXISTENCE:mutant phenotype:GO:1902626 assembly of large subunit precursor of preribosome [PMID:22735702]
note: Nucleolar protein required for 60S ribosome subunit biogenesis; constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p
codon start: 1
product: ribosome biosynthesis protein NIP7
translation: MRQLTEEETKVVFEKLAGYIGRNISFLVDNKELPHVFRLQKDRVYYVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFAMNDVPLGFGVSAKSTSESRNMQPTGIVAFRQADIGEYLRDEDTLFT
SIO_010081: YPL211W
subclass of: SO_0000673
so part of: YPL211W
location: 153495..154040
location: region:153495-154040:1
so has part: feature:153495-154040:1:exon

NP_015113.1
type: Protein
SIO_000068: ncbiprotein

S000006132
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:153495-154040:1:exon

YPL210C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SRP72
locus tag: YPL210C
so part of: sequence
location: complement(<154290..>156212)
location: region:154290-156212:-1
so has part: feature:154290-156212:-1:exon
subclass of: SO_0000010

855891
type: Gene
SIO_000068: ncbigene

position:154290:-1
position: 154290
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:156212:-1
position: 156212
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154290-156212:-1:exon

YPL210C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SRP72
locus tag: YPL210C
product: signal recognition particle subunit SRP72
transcript id: NM_001184024.1
SIO_010081: YPL210C
subclass of: SO_0000673
so part of: YPL210C
location: complement(<154290..>156212)
location: region:154290-156212:-1
so has part: feature:154290-156212:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154290-156212:-1:exon

YPL210C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SRP72
locus tag: YPL210C
experiment: EXISTENCE:direct assay:GO:0005786 signal recognition particle, endoplasmic reticulum targeting [PMID:7925282]
experiment: EXISTENCE:direct assay:GO:0006614 SRP-dependent cotranslational protein targeting to membrane [PMID:10921896]
note: Core component of the signal recognition particle (SRP); the SRP is a ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
codon start: 1
product: signal recognition particle subunit SRP72
translation: MAKDNLTNLLSQLNIQLSQDEHSQVEQTCVKLLDSGCENPADVFRRCLVAVIQQDKYQKALHYLKKFKHIDDKYGRKFALEKLYIFYKLNMPDEFNTLYTAIITDDLDTVLKKDIESLRGILHVRAQYCYKNGLYQEAFKIYQHLASHNEKDQDSQIELSCNERVPLSVATELMNRSPLVTPMDESSYDLLFNESFIMASVGKYDKAIELLEKALQGATNEGYQNDINTIKLQLSFVLQMVGKTAQSKEILKGLLQELKADSPFSLICQNNLNAFVDFSKYNTNFNLLLRELNVEKLNTFNLQTFTHEQWSNIQRNVLFLRLFNNVKIHSQESLLSRTFDKYSKLVDNVTLESYKTQAKKLYHHTTKTILSGTDGSTIGILLLTIQLLIIEKEWENAIRIGELFLNESWKSSFEKFNDSQAIVCYILFELYKIKGRNNSKSVLLKKLGSVRVQLSGKIQENIPFWKHVGFELLSMGNAKESKALLREISNFSKGDADVLVDRVVSSDSLDIAQGIDLVRDIDIDKLIQLGVKPLESSAKRSKNTAVSKVQKRKVLELKKKRKIKRLEKFLQGRDTSKLPDPERWLPLRDRSTYRPKKKQQGAKQTQGGAMNKKSEQALDISKKGKPTVNKKPKNKKKGRK
SIO_010081: YPL210C
subclass of: SO_0000673
so part of: YPL210C
location: complement(154290..156212)
location: region:154290-156212:-1
so has part: feature:154290-156212:-1:exon

NP_015114.2
type: Protein
SIO_000068: ncbiprotein

S000006131
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154290-156212:-1:exon

YPL209C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PAC15
gene: IPL1
locus tag: YPL209C
gene synonym: PAC15
so part of: sequence
location: complement(<156490..>157593)
location: region:156490-157593:-1
so has part: feature:156490-157593:-1:exon
subclass of: SO_0000010

855892
type: Gene
SIO_000068: ncbigene

position:156490:-1
position: 156490
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157593:-1
position: 157593
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156490-157593:-1:exon

YPL209C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PAC15
gene: IPL1
locus tag: YPL209C
gene synonym: PAC15
product: aurora kinase
transcript id: NM_001184023.1
SIO_010081: YPL209C
subclass of: SO_0000673
so part of: YPL209C
location: complement(<156490..>157593)
location: region:156490-157593:-1
so has part: feature:156490-157593:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156490-157593:-1:exon

YPL209C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PAC15
gene: IPL1
locus tag: YPL209C
gene synonym: PAC15
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:11511347|PMID:12566427]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:10072382|PMID:23142046|PMID:25387524|PMID:16319894|P MID:16143104]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005819 spindle [PMID:12566427]
experiment: EXISTENCE:direct assay:GO:0005828 kinetochore microtubule [PMID:11724818]
experiment: EXISTENCE:direct assay:GO:0005874 microtubule [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:11511347|PMID:11724818]
experiment: EXISTENCE:direct assay:GO:0032133 chromosome passenger complex [PMID:19158380]
experiment: EXISTENCE:direct assay:GO:0051233 spindle midzone [PMID:12566427]
experiment: EXISTENCE:genetic interaction:GO:0044774 mitotic DNA integrity checkpoint signaling [PMID:16651657]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:8293973]
experiment: EXISTENCE:mutant phenotype:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:10072382]
experiment: EXISTENCE:mutant phenotype:GO:0032465 regulation of cytokinesis [PMID:16615892]
experiment: EXISTENCE:mutant phenotype:GO:0045143 homologous chromosome segregation [PMID:17289568]
experiment: EXISTENCE:mutant phenotype:GO:0045144 meiotic sister chromatid segregation [PMID:17289568|PMID:17371833]
experiment: EXISTENCE:mutant phenotype:GO:0051228 mitotic spindle disassembly [PMID:12566427]
experiment: EXISTENCE:mutant phenotype:GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint [PMID:16327780]
experiment: EXISTENCE:mutant phenotype:GO:1901673 regulation of mitotic spindle assembly [PMID:24386320]
experiment: EXISTENCE:mutant phenotype:GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint [PMID:23177738]
note: Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest
codon start: 1
product: aurora kinase
translation: MQRNSLVNIKLNANSPSKKTTTRPNTSRINKPWRISHSPQQRNPNSKIPSPVREKLNRLPVNNKKFLDMESSKIPSPIRKATSSKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL
SIO_010081: YPL209C
subclass of: SO_0000673
so part of: YPL209C
location: complement(156490..157593)
location: region:156490-157593:-1
so has part: feature:156490-157593:-1:exon

NP_015115.1
type: Protein
SIO_000068: ncbiprotein

S000006130
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156490-157593:-1:exon

YPL208W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RKM1
locus tag: YPL208W
so part of: sequence
location: <157842..>159593
location: region:157842-159593:1
so has part: feature:157842-159593:1:exon
subclass of: SO_0000010

855893
type: Gene
SIO_000068: ncbigene

position:157842:1
position: 157842
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:159593:1
position: 159593
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:157842-159593:1:exon

YPL208W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RKM1
locus tag: YPL208W
product: protein-lysine N-methyltransferase
transcript id: NM_001184022.1
SIO_010081: YPL208W
subclass of: SO_0000673
so part of: YPL208W
location: <157842..>159593
location: region:157842-159593:1
so has part: feature:157842-159593:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:157842-159593:1:exon

YPL208W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RKM1
locus tag: YPL208W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016279 protein-lysine N-methyltransferase activity [PMID:16096273]
experiment: EXISTENCE:direct assay:GO:0018027 peptidyl-lysine dimethylation [PMID:16096273]
experiment: EXISTENCE:mutant phenotype:GO:0016279 protein-lysine N-methyltransferase activity [PMID:16096273]
experiment: EXISTENCE:mutant phenotype:GO:0018026 peptidyl-lysine monomethylation [PMID:22522802]
experiment: EXISTENCE:mutant phenotype:GO:0018027 peptidyl-lysine dimethylation [PMID:16096273]
note: SET-domain lysine-N-methyltransferase; catalyzes the formation of dimethyllysine residues on the large ribosomal subunit proteins L23 (Rpl23Ap and Rpl23Bp) and monomethyllysine residues on L18 (Rps18Ap and Rps18Bp)
codon start: 1
product: protein-lysine N-methyltransferase
translation: MSSDALKALLQWGASFGVIVPEELKFLYTDLKGIICVCEKDIDNPSIKIPPEIVISRNLPMKFFGLSESTKNINGWLKLFFAKIKFDRDNDTIVDNVRVNDKFKPYLDALPSRLNSPLVWNPSELKRLSSTNIGNSIHEKFEGIFKEWFELVSSSDMFDLERVADDVQTFHNLDELTYEALYEKILKITELQRPTIWYSFPAFLWSHLIFISRAFPEYVLNRNCPDNSIVLLPIVDLLNHDYRSKVKWYPENGWFCYEKIGTASQSRELSNNYGGKGNEELLSGYGFVLEDNIFDSVALKVKLPLDVVSTILETEPSLKLPLLSDYTTYAFENKDCVQQEKKATRSATDYINGVTYFINIQNEQCLEPLLDLFTYLSKAEEEDLHDLRARLQGIQMLRNALQSKLNSITGPPATDDSYAIDPYRVYCADVYTKGQKQILKEALTRLKKLEKTMLSENKHQLLTMSKILKNDPAFAETELPSLFSNEDGEEVIFESTYDLLILWILLKTKKNSYPTKYEWVGQQYTNFKQTAYISDDAKAFHTAYFEKQDDVDLAEVDHAIQFVVDNSFTRTSSTTEETILVRK
SIO_010081: YPL208W
subclass of: SO_0000673
so part of: YPL208W
location: 157842..159593
location: region:157842-159593:1
so has part: feature:157842-159593:1:exon

NP_015116.1
type: Protein
SIO_000068: ncbiprotein

S000006129
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:157842-159593:1:exon

YPL207W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TYW1
locus tag: YPL207W
so part of: sequence
location: <159909..>162341
location: region:159909-162341:1
so has part: feature:159909-162341:1:exon
subclass of: SO_0000010

855894
type: Gene
SIO_000068: ncbigene

position:159909:1
position: 159909
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:162341:1
position: 162341
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:159909-162341:1:exon

YPL207W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TYW1
locus tag: YPL207W
product: putative tRNA 4-demethylwyosine synthase
transcript id: NM_001184021.1
SIO_010081: YPL207W
subclass of: SO_0000673
so part of: YPL207W
location: <159909..>162341
location: region:159909-162341:1
so has part: feature:159909-162341:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:159909-162341:1:exon

YPL207W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TYW1
locus tag: YPL207W
EC number: 4.1.3.44
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0031591 wybutosine biosynthetic process [PMID:34184886]
experiment: EXISTENCE:direct assay:GO:1904047 S-adenosyl-L-methionine binding [PMID:34184886]
experiment: EXISTENCE:mutant phenotype:GO:0031591 wybutosine biosynthetic process [PMID:16162496|PMID:16642040|PMID:17150819]
note: Iron-sulfur protein required for synthesis of wybutosine modified tRNA; wybutosine is a modified guanosine found at 3'-position adjacent to anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron
codon start: 1
product: putative tRNA 4-demethylwyosine synthase
translation: MDGFRVAGALVVGALTAAYLYFGGRFSIALVIIVGYGIYCNEASGGSQDSQEKLDLNKQQKKPCCSDKKIADGGKKTGGCCSDKKNGGGKGGGCCSSKGGKKGGCCSSKGGKKGGCCSSKKNIGDNENTATEVEKAVNYPVTVDFTEVFRKPTKKRSSTPKVFSKNSSSNSRVGKKLSVSKKIGPDGLIKSALTISNETLLSSQIYVLYSSLQGAASKAAKSVYDKLKELDELTNEPKLLNLDDLSDFDDYFINVPVENALYVLVLPSYDIDCPLDYFLQTLEENANDFRVDSFPLRKLVGYTVLGLGDSESWPEKFCYQAKRADHWISRLGGRRIFPLGKVCMKTGGSAKIDEWTSLLAETLKDDEPIIYEYDENADSEEDEEEGNGSDELGDVEDIGGKGSNGKFSGADEIKQMVAKDSPTYKNLTKQGYKVIGSHSGVKICRWTKNELRGKGSCYKKSLFNIASSRCMELTPSLACSSKCVFCWRHGTNPVSKNWRWEVDEPEYILENALKGHYSMIKQMRGVPGVIAERFAKAFEVRHCALSLVGEPILYPHINKFIQLLHQKGITSFLVCNAQHPEALRNIVKVTQLYVSIDAPTKTELKKVDRPLYKDFWERMVECLEILKTVQNHQRTVFRLTLVKGFNMGDVSAYADLVQRGLPGFIEVKGATFSGSSDGNGNPLTMQNIPFYEECVKFVKAFTTELQRRGLHYDLAAEHAHSNCLLIADTKFKINGEWHTHIDFDKFFVLLNSGKDFTYMDYLEKTPEWALFGNGGFAPGNTRVYRKDKKKQNKENQETTTRETPLPPIPA
SIO_010081: YPL207W
subclass of: SO_0000673
so part of: YPL207W
location: 159909..162341
location: region:159909-162341:1
so has part: feature:159909-162341:1:exon

NP_015117.1
type: Protein
SIO_000068: ncbiprotein

S000006128
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:159909-162341:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1608; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 162341..162632
location: region:162341-162632:1
so has part: feature:162341-162632:1:region

S000130196
type: SGD
SIO_000068: sgd

position:162632:1
position: 162632
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162341-162632:1:region

YPL206C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PGC1
locus tag: YPL206C
so part of: sequence
location: complement(<162632..>163597)
location: region:162632-163597:-1
so has part: feature:162632-163597:-1:exon
subclass of: SO_0000010

855895
type: Gene
SIO_000068: ncbigene

position:162632:-1
position: 162632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:163597:-1
position: 163597
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162632-163597:-1:exon

YPL206C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PGC1
locus tag: YPL206C
product: phosphatidylglycerol phospholipase
transcript id: NM_001184020.1
SIO_010081: YPL206C
subclass of: SO_0000673
so part of: YPL206C
location: complement(<162632..>163597)
location: region:162632-163597:-1
so has part: feature:162632-163597:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:162632-163597:-1:exon

YPL206C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PGC1
locus tag: YPL206C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:18434318|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:12514182|PMID:24868093]
experiment: EXISTENCE:direct assay:GO:0034479 phosphatidylglycerol phospholipase C activity [PMID:18434318]
experiment: EXISTENCE:mutant phenotype:GO:0034478 phosphatidylglycerol catabolic process [PMID:18434318]
experiment: EXISTENCE:mutant phenotype:GO:0034479 phosphatidylglycerol phospholipase C activity [PMID:18434318]
experiment: EXISTENCE:mutant phenotype:GO:0046475 glycerophospholipid catabolic process [PMID:16172116]
note: Phosphatidylglycerol phospholipase C; regulates phosphatidylglycerol (PG) accumulation via a phospholipase C-type degradation mechanism; PG levels affect mitochondrial function; contains glycerophosphodiester phosphodiesterase motifs
codon start: 1
product: phosphatidylglycerol phospholipase
translation: MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLNDPHYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRTIHFL
SIO_010081: YPL206C
subclass of: SO_0000673
so part of: YPL206C
location: complement(162632..163597)
location: region:162632-163597:-1
so has part: feature:162632-163597:-1:exon

NP_015118.1
type: Protein
SIO_000068: ncbiprotein

S000006127
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:162632-163597:-1:exon

YPL204W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KTI14
gene: HRR25
locus tag: YPL204W
gene synonym: KTI14
so part of: sequence
location: <164276..>165760
location: region:164276-165760:1
so has part: feature:164276-165760:1:exon
subclass of: SO_0000010

855897
type: Gene
SIO_000068: ncbigene

position:164276:1
position: 164276
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:165760:1
position: 165760
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:164276-165760:1:exon

YPL204W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KTI14
gene: HRR25
locus tag: YPL204W
gene synonym: KTI14
product: serine/threonine protein kinase HRR25
transcript id: NM_001184018.1
SIO_010081: YPL204W
subclass of: SO_0000673
so part of: YPL204W
location: <164276..>165760
location: region:164276-165760:1
so has part: feature:164276-165760:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:164276-165760:1:exon

YPL204W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KTI14
gene: HRR25
locus tag: YPL204W
gene synonym: KTI14
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:26195667]
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:16990132]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:29915153]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:1495994|PMID:21532587|PMID:25569479]
experiment: EXISTENCE:direct assay:GO:0004713 protein tyrosine kinase activity [PMID:7803855]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8034689]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:22375831]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:21532587]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:17461799]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:8034689]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:14597664|PMID:17461799]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14597664|PMID:17461799|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:32317286]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:15167894]
experiment: EXISTENCE:direct assay:GO:0033551 monopolin complex [PMID:16990132]
experiment: EXISTENCE:direct assay:GO:0042274 ribosomal small subunit biogenesis [PMID:25778921]
experiment: EXISTENCE:direct assay:GO:0060628 regulation of ER to Golgi vesicle-mediated transport [PMID:21532587]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:16990132]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:1887218]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:25287303]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:14597664]
experiment: EXISTENCE:mutant phenotype:GO:0033551 monopolin complex [PMID:16990132]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:18256024]
experiment: EXISTENCE:mutant phenotype:GO:0042274 ribosomal small subunit biogenesis [PMID:16738661|PMID:25778921]
experiment: EXISTENCE:mutant phenotype:GO:0051455 monopolar spindle attachment to meiosis I kinetochore [PMID:16990132]
experiment: EXISTENCE:mutant phenotype:GO:0060628 regulation of ER to Golgi vesicle-mediated transport [PMID:21532587]
experiment: EXISTENCE:mutant phenotype:GO:0106214 regulation of vesicle fusion with Golgi apparatus [PMID:26195667]
experiment: EXISTENCE:mutant phenotype:GO:2000370 positive regulation of clathrin-dependent endocytosis [PMID:25287303]
experiment: EXISTENCE:mutant phenotype:GO:2000785 regulation of autophagosome assembly [PMID:26195667]
experiment: EXISTENCE:mutant phenotype:GO:2001159 regulation of protein localization by the Cvt pathway [PMID:24968893|PMID:25287303]
experiment: EXISTENCE:physical interaction:GO:0033551 monopolin complex [PMID:16990132]
note: Conserved casein kinase, monopolin subunit; regulates diverse events including vesicular traffic, DNA repair, CVT pathway, cohesion cleavage, attachment of sister kinetochores at meiosis I, exit from meiosis II, and ribosomal subunit biogenesis; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p; homolog of mammalian CK1delta
codon start: 1
product: serine/threonine protein kinase HRR25
translation: MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAASASNSTDNKSETFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILNNNAASSLPEELLNALDKGMENLRQQQPQQQVQSSQPQPQPQQLQQQPNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRATQYPPQINSNNFNTNQASVPPQMRSNPQQPPQDKPAGQSIWL
SIO_010081: YPL204W
subclass of: SO_0000673
so part of: YPL204W
location: 164276..165760
location: region:164276-165760:1
so has part: feature:164276-165760:1:exon

NP_015120.1
type: Protein
SIO_000068: ncbiprotein

S000006125
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:164276-165760:1:exon

YPL203W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PKA2
alternative label: PKA3
alternative label: YKR1
gene: TPK2
locus tag: YPL203W
gene synonym: PKA2; PKA3; YKR1
so part of: sequence
location: <166256..>167398
location: region:166256-167398:1
so has part: feature:166256-167398:1:exon
subclass of: SO_0000010

855898
type: Gene
SIO_000068: ncbigene

position:166256:1
position: 166256
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167398:1
position: 167398
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166256-167398:1:exon

YPL203W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PKA2
alternative label: PKA3
alternative label: YKR1
gene: TPK2
locus tag: YPL203W
gene synonym: PKA2; PKA3; YKR1
product: cAMP-dependent protein kinase catalytic subunit TPK2
transcript id: NM_001184017.1
SIO_010081: YPL203W
subclass of: SO_0000673
so part of: YPL203W
location: <166256..>167398
location: region:166256-167398:1
so has part: feature:166256-167398:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:166256-167398:1:exon

YPL203W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PKA2
alternative label: PKA3
alternative label: YKR1
gene: TPK2
locus tag: YPL203W
gene synonym: PKA2; PKA3; YKR1
EC number: 2.7.11.11
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:26403272]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:22899713]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004691 cAMP-dependent protein kinase activity [PMID:12024012|PMID:36167807]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12024012|PMID:18417610|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005952 cAMP-dependent protein kinase complex [PMID:12024012]
experiment: EXISTENCE:genetic interaction:GO:0004691 cAMP-dependent protein kinase activity [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0005952 cAMP-dependent protein kinase complex [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0007265 Ras protein signal transduction [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly [PMID:21925385]
experiment: EXISTENCE:genetic interaction:GO:0010737 protein kinase A signaling [PMID:20133652]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:12150916]
experiment: EXISTENCE:mutant phenotype:GO:0004691 cAMP-dependent protein kinase activity [PMID:36167807]
experiment: EXISTENCE:mutant phenotype:GO:0071333 cellular response to glucose stimulus [PMID:36167807]
experiment: EXISTENCE:mutant phenotype:GO:2000766 negative regulation of cytoplasmic translation [PMID:22899713]
experiment: EXISTENCE:physical interaction:GO:0005952 cAMP-dependent protein kinase complex [PMID:12024012]
experiment: EXISTENCE:physical interaction:GO:0031369 translation initiation factor binding [PMID:22899713]
note: cAMP-dependent protein kinase catalytic subunit; promotes nutrient responsive growth via the Ras-cAMP signaling pathway; phosphorylates and inhibits histone demethylase Jhd2p in response to glucose, promoting H3K4 trimethylation and maintaining H3K14 acetylation by preventing chromatin binding of Rpd3p; required for Sfl1p-mediated pseudohyphal growth; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: cAMP-dependent protein kinase catalytic subunit TPK2
translation: MEFVAERAQPVGQTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF
SIO_010081: YPL203W
subclass of: SO_0000673
so part of: YPL203W
location: 166256..167398
location: region:166256-167398:1
so has part: feature:166256-167398:1:exon

NP_015121.1
type: Protein
SIO_000068: ncbiprotein

S000006124
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166256-167398:1:exon

YPL202C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AFT2
locus tag: YPL202C
so part of: sequence
location: complement(<168088..>169338)
location: region:168088-169338:-1
so has part: feature:168088-169338:-1:exon
subclass of: SO_0000010

855899
type: Gene
SIO_000068: ncbigene

position:168088:-1
position: 168088
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:169338:-1
position: 169338
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:168088-169338:-1:exon

YPL202C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AFT2
locus tag: YPL202C
product: Aft2p
transcript id: NM_001184016.1
SIO_010081: YPL202C
subclass of: SO_0000673
so part of: YPL202C
location: complement(<168088..>169338)
location: region:168088-169338:-1
so has part: feature:168088-169338:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:168088-169338:-1:exon

YPL202C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AFT2
locus tag: YPL202C
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:16024809]
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:27402848]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11448968]
experiment: EXISTENCE:genetic interaction:GO:0006879 cellular iron ion homeostasis [PMID:16024809]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:11448968]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:16024809]
experiment: EXISTENCE:mutant phenotype:GO:0032048 cardiolipin metabolic process [PMID:27402848]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:27402848]
experiment: EXISTENCE:mutant phenotype:GO:0051536 iron-sulfur cluster binding [PMID:31493153]
experiment: EXISTENCE:mutant phenotype:GO:2000185 regulation of phosphate transmembrane transport [PMID:27618952]
note: Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
codon start: 1
product: Aft2p
translation: MKAKSMKSIISVPISVSKTGKMKLTASPDNLASMMSKDQNKLIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVRSKVGLNPKSKGSSSRSHACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPLVTPIISCDCGLTKEIEAFNNIFLPLSNPPLTSKKNLLKTNKNSVSKIKSRQMDNSKPRPRLKTKLDADLHDTGFLDNFKTRNSCVKIEKEDSLTNLNEIDFTNMFCNDNFIQNYNQGLMELLTEPTPGPSSSSCILPSTPTRPLSQSKMDIALSESTTSSPNFMETDAPYGDEIIKVSKDTKSNAPTADTDIATNLGKERNENFGMLNYNYEALLHFNDEHFNELNSIDPALISKY
SIO_010081: YPL202C
subclass of: SO_0000673
so part of: YPL202C
location: complement(168088..169338)
location: region:168088-169338:-1
so has part: feature:168088-169338:-1:exon

NP_015122.1
type: Protein
SIO_000068: ncbiprotein

S000006123
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:168088-169338:-1:exon

YPL201C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YIG1
locus tag: YPL201C
so part of: sequence
location: complement(<169770..>171155)
location: region:169770-171155:-1
so has part: feature:169770-171155:-1:exon
subclass of: SO_0000010

855900
type: Gene
SIO_000068: ncbigene

position:169770:-1
position: 169770
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171155:-1
position: 171155
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169770-171155:-1:exon

YPL201C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YIG1
locus tag: YPL201C
product: Yig1p
transcript id: NM_001184015.1
SIO_010081: YPL201C
subclass of: SO_0000673
so part of: YPL201C
location: complement(<169770..>171155)
location: region:169770-171155:-1
so has part: feature:169770-171155:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:169770-171155:-1:exon

YPL201C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YIG1
locus tag: YPL201C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16358322]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:16358322]
experiment: EXISTENCE:mutant phenotype:GO:0006114 glycerol biosynthetic process [PMID:16358322]
note: Protein that interacts with glycerol 3-phosphatase; plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol
codon start: 1
product: Yig1p
translation: MGIPMQIYQDGKGVQFYHTRYQNVFDERASKYGNYTVNNDYPQLPDTIKEHIDQLTFSNVGEDGGDVGNYSEEDDDGDEEKELEDVFRSNRGLEFVRINNYFTTHDLQSFKSFRNFNSKYWIFYSNQAEDKKLLLYDFNGQHLIFIKQQFYGQLNLLLSDAIICMDCNFGYNSNTIQILVGFQNGKLLKLNCDLNGNVNNHLLLKDPSTSSHQSHLSILNVWAGLLPHFVVSFSLKDGLLITSLDHQQSNGSFQSFHTNIDLPVDLRTTTNVKSVLNFPQFTLYKGNDMIFHCKNLLGSDASTLNKEINFMLKIDEDVQKIDYLLKTNHILLETNMRYLSIPTRDPIENSNSSPPVSDSEVYPIFYKTQELHVHASGTGRQIANNGKYIFITEQHLYGTALSVYKYSISFKRWLFVGYSDIRAKYGIRSVKDLFVGNCPSVNSPVLTILTDDNNIQTILLK
SIO_010081: YPL201C
subclass of: SO_0000673
so part of: YPL201C
location: complement(169770..171155)
location: region:169770-171155:-1
so has part: feature:169770-171155:-1:exon

NP_015123.1
type: Protein
SIO_000068: ncbiprotein

S000006122
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:169770-171155:-1:exon

YPL200W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSM4
locus tag: YPL200W
so part of: sequence
location: <171484..>171954
location: region:171484-171954:1
so has part: feature:171484-171954:1:exon
subclass of: SO_0000010

855901
type: Gene
SIO_000068: ncbigene

position:171484:1
position: 171484
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171954:1
position: 171954
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:171484-171954:1:exon

YPL200W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSM4
locus tag: YPL200W
product: Csm4p
transcript id: NM_001184014.1
SIO_010081: YPL200W
subclass of: SO_0000673
so part of: YPL200W
location: <171484..>171954
location: region:171484-171954:1
so has part: feature:171484-171954:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:171484-171954:1:exon

YPL200W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSM4
locus tag: YPL200W
experiment: EXISTENCE:direct assay:GO:0000781 chromosome, telomeric region [PMID:18585352]
experiment: EXISTENCE:direct assay:GO:0005640 nuclear outer membrane [PMID:32059771]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:12514182]
experiment: EXISTENCE:genetic interaction:GO:0045141 meiotic telomere clustering [PMID:18585352]
experiment: EXISTENCE:mutant phenotype:GO:0007129 homologous chromosome pairing at meiosis [PMID:21339478]
experiment: EXISTENCE:mutant phenotype:GO:0010520 regulation of reciprocal meiotic recombination [PMID:18818741|PMID:18818742]
experiment: EXISTENCE:mutant phenotype:GO:0034993 meiotic nuclear membrane microtubule tethering complex [PMID:32059771]
experiment: EXISTENCE:mutant phenotype:GO:0045132 meiotic chromosome segregation [PMID:11470404]
experiment: EXISTENCE:mutant phenotype:GO:0045141 meiotic telomere clustering [PMID:18818742|PMID:18585352]
experiment: EXISTENCE:mutant phenotype:GO:0140444 cytoskeleton-nuclear membrane anchor activity [PMID:32059771]
note: Protein required for accurate chromosome segregation during meiosis; involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements; functions with meiosis-specific telomere-binding protein Ndj1p; CSM4 has a paralog, MPS2, that arose from the whole genome duplication
codon start: 1
product: Csm4p
translation: MMDGSITRKVTSTLSNQLATWKWKLQLSLLERKLATINNDYFLLQWELLFITNEVMKWKEMIAFLESQLFCTTQNFVAQETHDRETFQSLVDDYNKQLSENNLIISVLKSRPQLSSFPIYLSDEVCSHLKFVIAELNSLIIVFFISLVFLWVSIEV
SIO_010081: YPL200W
subclass of: SO_0000673
so part of: YPL200W
location: 171484..171954
location: region:171484-171954:1
so has part: feature:171484-171954:1:exon

NP_015124.1
type: Protein
SIO_000068: ncbiprotein

S000006121
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:171484-171954:1:exon

YPL199C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL199C
so part of: sequence
location: complement(<172033..>172755)
location: region:172033-172755:-1
so has part: feature:172033-172755:-1:exon
subclass of: SO_0000010

855902
type: Gene
SIO_000068: ncbigene

position:172033:-1
position: 172033
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:172755:-1
position: 172755
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:172033-172755:-1:exon

YPL199C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL199C
product: uncharacterized protein
transcript id: NM_001184013.1
SIO_010081: YPL199C
subclass of: SO_0000673
so part of: YPL199C
location: complement(<172033..>172755)
location: region:172033-172755:-1
so has part: feature:172033-172755:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:172033-172755:-1:exon

YPL199C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL199C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay [PMID:32234470]
note: Protein involved in nonstop mRNA decay; predicted to be palmitoylated
codon start: 1
product: uncharacterized protein
translation: MKGTGGVVVGTQNPVRDYNHSTDEEYQRLRRLADEAYKKRDQLSHESQTAYQQGDKKLAHELSEKSKAQLKTAEDFNMQAAEYVFVENNADSSSNEIDLHGLYVKEALFILQKRIKFAIDHNEPQLNVIVGKGLHSQNGIAKLKPSIEEFCAKHGIRNHLEKGNSGVLVLELQGVQMQMDGPAVNAPTNQYNAQPHPQYNNNGGQPQGQAQNYNNSGNDNKDSTLTSIFKIFCNCIQSLA
SIO_010081: YPL199C
subclass of: SO_0000673
so part of: YPL199C
location: complement(172033..172755)
location: region:172033-172755:-1
so has part: feature:172033-172755:-1:exon

NP_015125.1
type: Protein
SIO_000068: ncbiprotein

S000006120
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:172033-172755:-1:exon

YPL198W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL7B
locus tag: YPL198W
so part of: sequence
location: <173152..>174702
location: region:173152-174702:1
so has part: feature:173152-174702:1:exon
subclass of: SO_0000010

855903
type: Gene
SIO_000068: ncbigene

position:173152:1
position: 173152
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:174702:1
position: 174702
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:173152-174702:1:exon

YPL198W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL7B
locus tag: YPL198W
product: ribosomal 60S subunit protein L7B
transcript id: NM_001184012.1
SIO_010081: YPL198W
subclass of: SO_0000673
so part of: YPL198W
location: join(<173152..173162,173572..173665,174073..>174702)
location: region:173152-174702:1
so has part: feature:173152-173162:1:exon
so has part: feature:173572-173665:1:exon
so has part: feature:174073-174702:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:173152-173162:1:exon

position:173162:1
position: 173162
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:173572-173665:1:exon

position:173572:1
position: 173572
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:173665:1
position: 173665
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 3
SIO_000628: feature:174073-174702:1:exon

position:174073:1
position: 174073
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL198W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL7B
locus tag: YPL198W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:23874617]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:23874617]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:19466602]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:19466602]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:23874617]
experiment: EXISTENCE:direct assay:GO:0042273 ribosomal large subunit biogenesis [PMID:23945946]
experiment: EXISTENCE:mutant phenotype:GO:0000470 maturation of LSU-rRNA [PMID:22893726]
note: Ribosomal 60S subunit protein L7B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7B has a paralog, RPL7A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L7B
translation: MSTEKILTPESQLKKTKAQQKTAEQIAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKAMN
SIO_010081: YPL198W
subclass of: SO_0000673
so part of: YPL198W
location: join(173152..173162,173572..173665,174073..174702)
location: region:173152-174702:1
so has part: feature:173152-173162:1:exon
so has part: feature:173572-173665:1:exon
so has part: feature:174073-174702:1:exon

NP_015126.1
type: Protein
SIO_000068: ncbiprotein

S000006119
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173152-173162:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:173572-173665:1:exon

urn:…
SIO_000300: 3
SIO_000628: feature:174073-174702:1:exon

YNCP0003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR59
locus tag: YNCP0003W
so part of: sequence
location: 173827..173904
location: region:173827-173904:1
so has part: feature:173827-173904:1:exon
subclass of: SO_0000578

9164987
type: Gene
SIO_000068: ncbigene

position:173827:1
position: 173827
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:173904:1
position: 173904
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:173827-173904:1:exon

YNCP0003W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR59
locus tag: YNCP0003W
product: SNR59
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:10024243]
experiment: EXISTENCE:curator inference:GO:0031428 box C/D RNP complex [PMID:10024243]
note: C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of large subunit (LSU) rRNA at position A807
transcript id: NR_132266.1
SIO_010081: YNCP0003W
subclass of: SO_0000673
so part of: YNCP0003W
location: 173827..173904
location: region:173827-173904:1
so has part: feature:173827-173904:1:exon

S000006450
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173827-173904:1:exon

YPL196W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OXR1
locus tag: YPL196W
so part of: sequence
location: <175043..>175864
location: region:175043-175864:1
so has part: feature:175043-175864:1:exon
subclass of: SO_0000010

855905
type: Gene
SIO_000068: ncbigene

position:175043:1
position: 175043
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:175864:1
position: 175864
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:175043-175864:1:exon

YPL196W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OXR1
locus tag: YPL196W
product: Oxr1p
transcript id: NM_001184010.1
SIO_010081: YPL196W
subclass of: SO_0000673
so part of: YPL196W
location: <175043..>175864
location: region:175043-175864:1
so has part: feature:175043-175864:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:175043-175864:1:exon

YPL196W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OXR1
locus tag: YPL196W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:34918374]
experiment: EXISTENCE:direct assay:GO:0005515 protein binding [PMID:34918374]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:15060142]
experiment: EXISTENCE:direct assay:GO:0007035 vacuolar acidification [PMID:34918374]
note: Protein involved in regulation of vacuolar V-ATPase; inhibits V1-ATPase activity and triggers disassembly of V-ATPase holoenzyme; required for normal levels of resistance to oxidative damage; null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes
codon start: 1
product: Oxr1p
translation: MFGVKDAIFKIKRSIAGTDSSDSTAYTTASESSPQLKDSHNPFRNKTTSERTIVEEGSLPPVRLNGYLPSTKNKLLTPEMCDEIRTLMPTRIQLYTEWNLLYSLEQHGSSLHSLYSNVAPDSKEFRRVGYVLVIKDRKNGIFGAYSNEAFHPNEHRQYTGNGECFLWKLDKVPDVNISEKEESEQEGKEGKEEGDKEERWRFSGYPYTGVNEFAIYCTSEFLSMGAGDGHYGLLCDDGLLHGVSNPCQTYGNEVLSKEGKKFSIVALEVWRVG
SIO_010081: YPL196W
subclass of: SO_0000673
so part of: YPL196W
location: 175043..175864
location: region:175043-175864:1
so has part: feature:175043-175864:1:exon

NP_015128.1
type: Protein
SIO_000068: ncbiprotein

S000006117
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:175043-175864:1:exon

YPL195W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YKS4
gene: APL5
locus tag: YPL195W
gene synonym: YKS4
so part of: sequence
location: <176223..>179021
location: region:176223-179021:1
so has part: feature:176223-179021:1:exon
subclass of: SO_0000010

855906
type: Gene
SIO_000068: ncbigene

position:176223:1
position: 176223
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:179021:1
position: 179021
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:176223-179021:1:exon

YPL195W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YKS4
gene: APL5
locus tag: YPL195W
gene synonym: YKS4
product: Apl5p
transcript id: NM_001184009.1
SIO_010081: YPL195W
subclass of: SO_0000673
so part of: YPL195W
location: <176223..>179021
location: region:176223-179021:1
so has part: feature:176223-179021:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:176223-179021:1:exon

YPL195W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YKS4
gene: APL5
locus tag: YPL195W
gene synonym: YKS4
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:17895371]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:9335339]
experiment: EXISTENCE:mutant phenotype:GO:0030123 AP-3 adaptor complex [PMID:9250663]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:10559961]
note: Delta adaptin-like subunit of the clathrin associated protein complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; suppressor of loss of casein kinase 1 function; the clathrin associated protein complex is also known as AP-3
codon start: 1
product: Apl5p
translation: MTSLYAPGAEDIRQRLRPFGFFFEKSLKDLIKGIRSHNETPEKLDQFFKQVLSECREEVNSPDLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNSTRPYIRKKAITALFKVFLQYPEALRDNFDKFVSKLDDDDISVVSAAVSVICELSKKNPQPFIQLSPLLYEILVTIDNNWIIIRLLKLFTNLSQVEPKLRAKLLPKILELMESTVATSVIYESVNCIVKGNMLEEDDFETAMACLERLHTFCDSQDPNLRYISCILFYKIGKINTDFISRFDQLIIRLLSDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIIIPENYKIKMVNVIISICSADNYSSVNDFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRNLMIKVPSMREVTIANIIKLISNDNINKQLPTVLRECIWCLGEFSTLVENGNDLIKIMTENISYYSHSVQEVLILALVKVFSNWCNNFQEDKRFEIKMVLKELIEFFENLSYSSTFEVQERSVEVLEFLRLSLEALEEDTEGLPMLLSEVLPSFFNAYELAPIARGTQLKLAVDENLDLETPFLTKEAADELLDEQKSDAISDLMSDISMDEQVELKFVDDSDTSYEEKEKLDDFENPFEIEREKERMSNPYYLGEEDEERTKNSKDLLDLNEEESSDKKPETIRLNRTDNSLNSLSLSTTEISRKKKKGKKKNRVQVLSDEPVIEAAPKRKDAFQKPHDNHSTQNPLKKDKINLRMHSQLENFDFSNFGQSSNAGRGSQEEGNLRKEDELELSRLEANLIVKDEKDNLSDTEEVIVIKKKKKGKKSKSKNKLKTKAKNSPEPNEFLRDQSTDI
SIO_010081: YPL195W
subclass of: SO_0000673
so part of: YPL195W
location: 176223..179021
location: region:176223-179021:1
so has part: feature:176223-179021:1:exon

NP_015129.1
type: Protein
SIO_000068: ncbiprotein

S000006116
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:176223-179021:1:exon

YPL194W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DDC1
locus tag: YPL194W
so part of: sequence
location: <179277..>181115
location: region:179277-181115:1
so has part: feature:179277-181115:1:exon
subclass of: SO_0000010

855907
type: Gene
SIO_000068: ncbigene

position:179277:1
position: 179277
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:181115:1
position: 181115
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:179277-181115:1:exon

YPL194W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DDC1
locus tag: YPL194W
product: Ddc1p
transcript id: NM_001184008.1
SIO_010081: YPL194W
subclass of: SO_0000673
so part of: YPL194W
location: <179277..>181115
location: region:179277-181115:1
so has part: feature:179277-181115:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:179277-181115:1:exon

YPL194W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DDC1
locus tag: YPL194W
experiment: EXISTENCE:direct assay:GO:0000725 recombinational repair [PMID:16840526]
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:11825877]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0030295 protein kinase activator activity [PMID:31340146]
experiment: EXISTENCE:direct assay:GO:0030896 checkpoint clamp complex [PMID:12604797|PMID:9670034|PMID:9891048]
experiment: EXISTENCE:direct assay:GO:0032147 activation of protein kinase activity [PMID:31340146]
experiment: EXISTENCE:genetic interaction:GO:0000725 recombinational repair [PMID:16840526]
experiment: EXISTENCE:mutant phenotype:GO:0007095 mitotic G2 DNA damage checkpoint signaling [PMID:9311982]
experiment: EXISTENCE:mutant phenotype:GO:0031571 mitotic G1 DNA damage checkpoint signaling [PMID:9311982]
experiment: EXISTENCE:mutant phenotype:GO:0031573 mitotic intra-S DNA damage checkpoint signaling [PMID:9311982]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:11825877]
experiment: EXISTENCE:mutant phenotype:GO:0051598 meiotic recombination checkpoint signaling [PMID:11825877]
note: DNA damage checkpoint protein; part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate; forms nuclear foci upon DNA replication stress
codon start: 1
product: Ddc1p
translation: MSFKATITESGKQNIWFRAIYVLSTIQDDIKITVTTNELIAWSMNETDTTLCQVRFQKSFFEEYEFKPHEIVFGENGVQVIEDTYGNSHKLYSFRVNGRHLTTISRKPDGDGIKSFTIAVNNTSTCPESLANRLIVVIEMDSLIVKEYCPQFQPIKYDPIIINLKYKRRFLDVFGTAASDRNPQEPLDPKLLDVFTNTERELTSALFNEEVESDIRKRNQLTAADEINYICCNSTLLKNFLDNCNVNVTDEVKLEINVHRLSITAFTKAVYGKNNDLLRNALSMSNTISTLDLEHYCLFTTIEDEKQDKRSHSKRREHMKSIIFKLKDFKNFITIGPSWKTTQDGNDNISLWFCHPGDPILMQMQKPGVKLELVEVTDSNINDDILEGKFIKTAISGSKEEAGLKDNKESCESPLKSKTALKRENLPHSVAGTRNSPLKVSYLTPDNGSTVAKTYRNNTARKLFVEEQSQSTNYEQDKRFRQASSVHMNMNREQSFDIGTTHEVACPRNESNSLKRSIADICNETEDPTQQSTFAKRADTTVTWGKALPAADDEVSCSNIDRKGMLKKEKLKHMQGLLNSQNDTSNHKKQDNKEMEDGLGLTQVEKPRGIFD
SIO_010081: YPL194W
subclass of: SO_0000673
so part of: YPL194W
location: 179277..181115
location: region:179277-181115:1
so has part: feature:179277-181115:1:exon

NP_015130.1
type: Protein
SIO_000068: ncbiprotein

S000006115
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:179277-181115:1:exon

YPL193W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RSA1
locus tag: YPL193W
so part of: sequence
location: <181403..>182548
location: region:181403-182548:1
so has part: feature:181403-182548:1:exon
subclass of: SO_0000010

855908
type: Gene
SIO_000068: ncbigene

position:181403:1
position: 181403
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:182548:1
position: 182548
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:181403-182548:1:exon

YPL193W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RSA1
locus tag: YPL193W
product: Rsa1p
transcript id: NM_001184007.1
SIO_010081: YPL193W
subclass of: SO_0000673
so part of: YPL193W
location: <181403..>182548
location: region:181403-182548:1
so has part: feature:181403-182548:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:181403-182548:1:exon

YPL193W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RSA1
locus tag: YPL193W
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:10567587]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:10567587]
experiment: EXISTENCE:mutant phenotype:GO:0000492 box C/D snoRNP assembly [PMID:25170085]
note: Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly
codon start: 1
product: Rsa1p
translation: MNYNNFENSKGDGHSRLPKPTYSGTLSDGYDESKIKRQKTDSAFNAAYSPHMYPNSPYYEGSWNTGYTPQLHHVAPHNQYFHPIQPSTQYNYTSPPNYTENYIPPVHQNISYAPALNLQKWPSSYCENTQALKNDKDYQTSISYEDVAIPTVKEIQLIEKNRGKDTFMNEISPVPSSKDQASAEPTEIPRKDPELANSNAEDDHNNLGLEDDDRDEQLESEGLGKVVLVPGTSIALITDEDVKKWREERKKMWLLKISNNKQKHMQEMGIKEDELKSQPSIFKESRKEKQFIQSIQNQVQRGNPKIDLNLKLIQREFANENSQLLDFIRELGDVGLLEYELSQQEKDVLFGSSEDNNKNHYKPNYKNRKPNLSRANFTRNK
SIO_010081: YPL193W
subclass of: SO_0000673
so part of: YPL193W
location: 181403..182548
location: region:181403-182548:1
so has part: feature:181403-182548:1:exon

NP_015131.1
type: Protein
SIO_000068: ncbiprotein

S000006114
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:181403-182548:1:exon

YPL192C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM3
locus tag: YPL192C
so part of: sequence
location: complement(<182655..>183056)
location: region:182655-183056:-1
so has part: feature:182655-183056:-1:exon
subclass of: SO_0000010

855909
type: Gene
SIO_000068: ncbigene

position:182655:-1
position: 182655
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:183056:-1
position: 183056
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182655-183056:-1:exon

YPL192C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM3
locus tag: YPL192C
product: pheromone-regulated protein PRM3
transcript id: NM_001184006.1
SIO_010081: YPL192C
subclass of: SO_0000673
so part of: YPL192C
location: complement(<182655..>183056)
location: region:182655-183056:-1
so has part: feature:182655-183056:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:182655-183056:-1:exon

YPL192C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM3
locus tag: YPL192C
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:12514182]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:19297527]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:12514182|PMID:19297527]
experiment: EXISTENCE:mutant phenotype:GO:0005635 nuclear envelope [PMID:12514182]
experiment: EXISTENCE:mutant phenotype:GO:0048288 nuclear membrane fusion involved in karyogamy [PMID:19297527]
note: Protein required for nuclear envelope fusion during karyogamy; pheromone-regulated; peripheral protein of the nuclear membrane; interacts with Kar5p at the spindle pole body
codon start: 1
product: pheromone-regulated protein PRM3
translation: MTAMKEDNAALITLKKNNDQEKLRVHKLTDASSNSADGFVINKAKNGGPLNKKSLVNNEQHIKKAVSPGRVRKHKTTTSSTKSRTKSKKKDASESKVQRENKGSFYQGAIFGSFLGAAVTTVLSNLAVKALQN
SIO_010081: YPL192C
subclass of: SO_0000673
so part of: YPL192C
location: complement(182655..183056)
location: region:182655-183056:-1
so has part: feature:182655-183056:-1:exon

NP_015132.1
type: Protein
SIO_000068: ncbiprotein

S000006113
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182655-183056:-1:exon

YPL191C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MIY1
gene: MIY2
locus tag: YPL191C
gene synonym: MIY1
so part of: sequence
location: complement(<183597..>184679)
location: region:183597-184679:-1
so has part: feature:183597-184679:-1:exon
subclass of: SO_0000010

855910
type: Gene
SIO_000068: ncbigene

position:183597:-1
position: 183597
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:184679:-1
position: 184679
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183597-184679:-1:exon

YPL191C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MIY1
gene: MIY2
locus tag: YPL191C
gene synonym: MIY1
product: ubiquitinyl hydrolase 1
transcript id: NM_001184005.1
SIO_010081: YPL191C
subclass of: SO_0000673
so part of: YPL191C
location: complement(<183597..>184679)
location: region:183597-184679:-1
so has part: feature:183597-184679:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:183597-184679:-1:exon

YPL191C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MIY1
gene: MIY2
locus tag: YPL191C
gene synonym: MIY1
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071108 protein K48-linked deubiquitination [PMID:27292798]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:1990380 K48-linked deubiquitinase activity [PMID:27292798]
note: K48-specific deubiquitinating (DUB) enzyme; MINDY family endo-type deubiquitinase that preferentially cleaves long K48-linked polyubiquitin chains between moieties; diploid deletion strain exhibits high budding index; GFP-fusion protein localizes to the cytoplasm endoplasmic reticulum and cell periphery in high-throughput studies; YPL191C has a paralog, YGL082W, that arose from the whole genome duplication; ortholog of human MINDY2/FAM63B
codon start: 1
product: ubiquitinyl hydrolase 1
translation: MDLSFTTKSVKINGQNHRILLQNENGPCALLALANILILSPDHTRFSNELIRLVNKGSQISLKELIEVLADIALQVTDKPSTDISELLSLLPRLHEGLNINPEFNGSFENTKEMSIFRLFNVDVVHGWVINSFINENIDEKLSHYSYESAQRILTQAADINCGISQDENSDEVLRDAMHLGLFLNESPTQLTAFGLLRLREKLLHNKFSILFRNDHFSTLFKYEDRLYTLVTDFGYKNCKDIVWQSLDSVDGSCDAFFAGNFSAAEVNGQQLSTDIERDFGTGNLLLEEIQQIENDKELAKQLQEQEQERVTKFEAKRKIHSHKKNSEIHAPVKKDKFKRRSSLLNAKASEKEKSECVVM
SIO_010081: YPL191C
subclass of: SO_0000673
so part of: YPL191C
location: complement(183597..184679)
location: region:183597-184679:-1
so has part: feature:183597-184679:-1:exon

NP_015133.1
type: Protein
SIO_000068: ncbiprotein

S000006112
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:183597-184679:-1:exon

YPL190C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HMD1
gene: NAB3
locus tag: YPL190C
gene synonym: HMD1
so part of: sequence
location: complement(<185317..>187725)
location: region:185317-187725:-1
so has part: feature:185317-187725:-1:exon
subclass of: SO_0000010

855911
type: Gene
SIO_000068: ncbigene

position:185317:-1
position: 185317
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:187725:-1
position: 187725
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:185317-187725:-1:exon

YPL190C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HMD1
gene: NAB3
locus tag: YPL190C
gene synonym: HMD1
product: Nab3p
transcript id: NM_001184004.1
SIO_010081: YPL190C
subclass of: SO_0000673
so part of: YPL190C
location: complement(<185317..>187725)
location: region:185317-187725:-1
so has part: feature:185317-187725:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:185317-187725:-1:exon

YPL190C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HMD1
gene: NAB3
locus tag: YPL190C
gene synonym: HMD1
experiment: EXISTENCE:direct assay:GO:0001068 transcription regulatory region RNA binding [PMID:21084293]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:20805243|PMID:31960028]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:7962083]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0030847 termination of RNA polymerase II transcription, exosome-dependent [PMID:16427013]
experiment: EXISTENCE:direct assay:GO:0035649 Nrd1 complex [PMID:10655211]
experiment: EXISTENCE:direct assay:GO:0071041 antisense RNA transcript catabolic process [PMID:27190003]
experiment: EXISTENCE:mutant phenotype:GO:0031124 mRNA 3'-end processing [PMID:11565036]
experiment: EXISTENCE:mutant phenotype:GO:0031126 sno(s)RNA 3'-end processing [PMID:11565036]
experiment: EXISTENCE:mutant phenotype:GO:0034472 snRNA 3'-end processing [PMID:11565036]
experiment: EXISTENCE:mutant phenotype:GO:0042780 tRNA 3'-end processing [PMID:21460797]
experiment: EXISTENCE:mutant phenotype:GO:0071028 nuclear mRNA surveillance [PMID:21113025]
experiment: EXISTENCE:mutant phenotype:GO:0071034 CUT catabolic process [PMID:16973436]
experiment: EXISTENCE:mutant phenotype:GO:0071041 antisense RNA transcript catabolic process [PMID:22028667]
note: RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability
codon start: 1
product: Nab3p
translation: MSDENHNSDVQDIPSPELSVDSNSNENELMNNSSADDGIEFDAPEEEREAEREEENEEQHELEDVNDEEEEDKEEKGEENGEVINTEEEEEEEHQQKGGNDDDDDDNEEEEEEEEDDDDDDDDDDDDEEEEEEEEEEGNDNSSVGSDSAAEDGEDEEDKKDKTKDKEVELRRETLEKEQKDVDEAIKKITREENDNTHFPTNMENVNYDLLQKQVKYIMDSNMLNLPQFQHLPQEEKMSAILAMLNSNSDTALSVPPHDSTISTTASASATSGARSNDQRKPPLSDAQRRMRFPRADLSKPITEEEHDRYAAYLHGENKITEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAFGFIQFDNPQSVRDAIECESQEMNFGKKLILEVSSSNARPQFDHGDHGTNSSSTFISSAKRPFQTESGDMYNDDNGAGYKKSRRHTVSCNIFVKRTADRTYAIEVFNRFRDGTGLETDMIFLKPRMELGKLINDAAYNGVWGVVLVNKTHNVDVQTFYKGSQGETKFDEYISISADDAVAIFNNIKNNRNNSRPTDYRAMSHQQNIYGAPPLPVPNGPAVGPPPQTNYYQGYSMPPPQQQQQQPYGNYGMPPPSHDQGYGSQPPIPMNQSYGRYQTSIPPPPPQQQIPQGYGRYQAGPPPQPPSQTPMDQQQLLSAIQNLPPNVVSNLLSMAQQQQQQPHAQQQLVGLIQSMQGQAPQQQQQQLGGYSSMNSSSPPPMSTNYNGQNISAKPSAPPMSHQPPPPQQQQQQQQQQQQQQQQPAGNNVQSLLDSLAKLQK
SIO_010081: YPL190C
subclass of: SO_0000673
so part of: YPL190C
location: complement(185317..187725)
location: region:185317-187725:-1
so has part: feature:185317-187725:-1:exon

NP_015134.1
type: Protein
SIO_000068: ncbiprotein

S000006111
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:185317-187725:-1:exon

YPL189C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COA2
locus tag: YPL189C-A
so part of: sequence
location: complement(<188307..>188513)
location: region:188307-188513:-1
so has part: feature:188307-188513:-1:exon
subclass of: SO_0000010

1466518
type: Gene
SIO_000068: ncbigene

position:188307:-1
position: 188307
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:188513:-1
position: 188513
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:188307-188513:-1:exon

YPL189C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COA2
locus tag: YPL189C-A
product: Coa2p
transcript id: NM_001184537.1
SIO_010081: YPL189C-A
subclass of: SO_0000673
so part of: YPL189C-A
location: complement(<188307..>188513)
location: region:188307-188513:-1
so has part: feature:188307-188513:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:188307-188513:-1:exon

YPL189C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COA2
locus tag: YPL189C-A
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:18541668]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:18541668]
experiment: EXISTENCE:physical interaction:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:18541668]
note: Cytochrome oxidase assembly factor; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity; functions downstream of assembly factors Mss51p and Coa1p and interacts with assembly factor Shy1p
codon start: 1
product: Coa2p
translation: MRAVTRNKIVNNLYFSTFLIAFASVAIGSVLPCPAHSVDSDSPAVQQHKLQLAHEQELKRKDALSKKI
SIO_010081: YPL189C-A
subclass of: SO_0000673
so part of: YPL189C-A
location: complement(188307..188513)
location: region:188307-188513:-1
so has part: feature:188307-188513:-1:exon

NP_878179.1
type: Protein
SIO_000068: ncbiprotein

S000028527
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:188307-188513:-1:exon

YPL189W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GUP2
locus tag: YPL189W
so part of: sequence
location: <189154..>190983
location: region:189154-190983:1
so has part: feature:189154-190983:1:exon
subclass of: SO_0000010

855912
type: Gene
SIO_000068: ncbigene

position:189154:1
position: 189154
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:190983:1
position: 190983
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:189154-190983:1:exon

YPL189W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GUP2
locus tag: YPL189W
product: putative O-acyltransferase
transcript id: NM_001184003.1
SIO_010081: YPL189W
subclass of: SO_0000673
so part of: YPL189W
location: <189154..>190983
location: region:189154-190983:1
so has part: feature:189154-190983:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:189154-190983:1:exon

YPL189W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GUP2
locus tag: YPL189W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0015793 glycerol transmembrane transport [PMID:10931309]
note: Probable membrane protein; possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; homolog of the mammalian Hedgehog pathway modulator HHAT; GUP2 has a paralog, GUP1, that arose from the whole genome duplication
codon start: 1
product: putative O-acyltransferase
translation: MSMLRIWSCIVHFFSVQALDSRIKPDIEFKRRQRIFINSSKEENGSSSSAVTVTRNPVLSSNSPSPPLWNTWEFRLYYLAFTVVVPFMIKAALATSSESNPNYYKFSGLLAHGWILGRKVDNSDPQYRFFRSNFFLLAILILLQIILKKVFVKFSKIPKTKFDFACGLVFVCFMYGINSVKLFTHAFIFFTLAHSLKRKRLIAAFAIWSYGIFTLFINQKMKNLPFNNIAIILSPMDQWYKGIVPRWDFFFNFTLLRLLSYSMDFLERWHEQLSRQPSIDYDDRRPEFRKSLSGSTLQTIYESGKNVLEEKERLVAEHHIQDYNFINFIAYITYAPLFLVGPIITFNDYLYQSENKLPSLTKKNIGFYALKVFSSLLLMEIILHYIYVGAIARTKAWNNDTPLQQAMIALFNLNIMYLKLLIPWRLFRLWAMVDGIDAPENMLRCVDNNYSTVGFWRAWHTSFNKWVIRYIYVPFGGSNNKILTSFAVFSFVAIWHDIQLRVLFWGWLTVLLLLGETYITNCFSRYRFRSWYRFVCGIGAAINICMMMIINVYGFCLGAEGTKLLLKGIFNNSHSPEFLTAVMVSLFIAVQVMFEIREEEKRHGINLKC
SIO_010081: YPL189W
subclass of: SO_0000673
so part of: YPL189W
location: 189154..190983
location: region:189154-190983:1
so has part: feature:189154-190983:1:exon

NP_015135.1
type: Protein
SIO_000068: ncbiprotein

S000006110
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:189154-190983:1:exon

YPL188W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POS5
locus tag: YPL188W
so part of: sequence
location: <191406..>192650
location: region:191406-192650:1
so has part: feature:191406-192650:1:exon
subclass of: SO_0000010

855913
type: Gene
SIO_000068: ncbigene

position:191406:1
position: 191406
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:192650:1
position: 192650
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191406-192650:1:exon

YPL188W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POS5
locus tag: YPL188W
product: NADH kinase
transcript id: NM_001184002.1
SIO_010081: YPL188W
subclass of: SO_0000673
so part of: YPL188W
location: <191406..>192650
location: region:191406-192650:1
so has part: feature:191406-192650:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:191406-192650:1:exon

YPL188W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POS5
locus tag: YPL188W
EC number: 2.7.1.86
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:12727869]
experiment: EXISTENCE:direct assay:GO:0006741 NADP biosynthetic process [PMID:12727869]
experiment: EXISTENCE:direct assay:GO:0042736 NADH kinase activity [PMID:12727869]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:20889970]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:7586028]
note: Mitochondrial NADH kinase; phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress
codon start: 1
product: NADH kinase
translation: MFVRVKLNKPVKWYRFYSTLDSHSLKLQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKTENDWIRGINELLGFNSSFRLTKRQTDND
SIO_010081: YPL188W
subclass of: SO_0000673
so part of: YPL188W
location: 191406..192650
location: region:191406-192650:1
so has part: feature:191406-192650:1:exon

NP_015136.1
type: Protein
SIO_000068: ncbiprotein

S000006109
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:191406-192650:1:exon

YPL187W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MF(ALPHA)1
locus tag: YPL187W
so part of: sequence
location: <193648..>194145
location: region:193648-194145:1
so has part: feature:193648-194145:1:exon
subclass of: SO_0000010

855914
type: Gene
SIO_000068: ncbigene

position:193648:1
position: 193648
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:194145:1
position: 194145
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:193648-194145:1:exon

YPL187W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MF(ALPHA)1
locus tag: YPL187W
product: Mf(Alpha)1p
transcript id: NM_001184001.1
SIO_010081: YPL187W
subclass of: SO_0000673
so part of: YPL187W
location: <193648..>194145
location: region:193648-194145:1
so has part: feature:193648-194145:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:193648-194145:1:exon

YPL187W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MF(ALPHA)1
locus tag: YPL187W
experiment: EXISTENCE:direct assay:GO:0000772 mating pheromone activity [PMID:6306574]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:776628]
experiment: EXISTENCE:direct assay:GO:1903135 cupric ion binding [PMID:27476515]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:3887136]
experiment: EXISTENCE:mutant phenotype:GO:0000772 mating pheromone activity [PMID:3887136]
note: Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor; binds copper(II) ions
codon start: 1
product: Mf(Alpha)1p
translation: MRFPSIFTAVLFAASSALAAPVNTTTEDETAQIPAEAVIGYLDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREAEAWHWLQLKPGQPMYKREAEAEAWHWLQLKPGQPMYKREADAEAWHWLQLKPGQPMYKREADAEAWHWLQLKPGQPMY
SIO_010081: YPL187W
subclass of: SO_0000673
so part of: YPL187W
location: 193648..194145
location: region:193648-194145:1
so has part: feature:193648-194145:1:exon

NP_015137.1
type: Protein
SIO_000068: ncbiprotein

S000006108
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:193648-194145:1:exon

YPL186C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UIP4
locus tag: YPL186C
so part of: sequence
location: complement(<194512..>195426)
location: region:194512-195426:-1
so has part: feature:194512-195426:-1:exon
subclass of: SO_0000010

855916
type: Gene
SIO_000068: ncbigene

position:194512:-1
position: 194512
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:195426:-1
position: 195426
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:194512-195426:-1:exon

YPL186C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UIP4
locus tag: YPL186C
product: Uip4p
transcript id: NM_001184000.1
SIO_010081: YPL186C
subclass of: SO_0000673
so part of: YPL186C
location: complement(<194512..>195426)
location: region:194512-195426:-1
so has part: feature:194512-195426:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:194512-195426:-1:exon

YPL186C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UIP4
locus tag: YPL186C
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:11056382]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11056382|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006998 nuclear envelope organization [PMID:35171083]
note: Protein required for nuclear envelope integrity; involved in distribution of nuclear pore complexes; interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope
codon start: 1
product: Uip4p
translation: MVTIVFDHPAEDFPELKIAGEFTNWEGVPMKINTSSGKWEYKFDESSVTKHNDKDKVHFKFIDQNGNWFADDEYPKEVDEHSNENNVATLNNEEDGGSAGEEKDEGDKTAHNTNENGSELYYEGPETPTPSLKGNVTFPSPKTAISQDGSAFAKETTRKERKYEHAPLNEVPVERDPKEENKELSPNFSQEQTENKQDKGLDNLSEGNDNDNTRVNEDTDVTDTQESEHEINGSDTENTDMSEQEEIQKIDKPADQNAKSIVKEGDANTEDYESVLKKLLGALGRFFGSWFSWLTTKMSSSEAS
SIO_010081: YPL186C
subclass of: SO_0000673
so part of: YPL186C
location: complement(194512..195426)
location: region:194512-195426:-1
so has part: feature:194512-195426:-1:exon

NP_015138.1
type: Protein
SIO_000068: ncbiprotein

S000006107
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:194512-195426:-1:exon

YPL184C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PTR69
gene: MRN1
locus tag: YPL184C
gene synonym: PTR69
so part of: sequence
location: complement(<195950..>197788)
location: region:195950-197788:-1
so has part: feature:195950-197788:-1:exon
subclass of: SO_0000010

855917
type: Gene
SIO_000068: ncbigene

position:195950:-1
position: 195950
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:197788:-1
position: 197788
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:195950-197788:-1:exon

YPL184C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PTR69
gene: MRN1
locus tag: YPL184C
gene synonym: PTR69
product: Mrn1p
transcript id: NM_001183998.1
SIO_010081: YPL184C
subclass of: SO_0000673
so part of: YPL184C
location: complement(<195950..>197788)
location: region:195950-197788:-1
so has part: feature:195950-197788:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:195950-197788:-1:exon

YPL184C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PTR69
gene: MRN1
locus tag: YPL184C
gene synonym: PTR69
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23028530]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23028530|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:genetic interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:23028530]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:23028530]
note: RNA-binding protein involved in translational regulation; links cell wall homeostasis to mitochondrial structure and function; binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES); interacts genetically with chromatin remodelers and splicing factors, linking chromatin state, splicing and as a result mRNA maturation
codon start: 1
product: Mrn1p
translation: MVVSYNNNNNNNNNNNNNNISNNNNNNNMFPPFPSSDDFAMYQQSSSSGPYQETYASGPQNFGDAVYPMNGNFTLLPSDFTREPNDSFFYENDGIFDYQRIQQQPTQFQTKQRNDSQQQRFSQEQNFEIDNEVVHNNNRYYEYERSSNEVSPFDDENPNVLSDGMSPTIMATATAVTNANAPLPVNAQANNPLNFTSAPSRTVYLGNVPPNLSVKELLDHVRSGVVEDVKIIPEKMCAFVSFIDESAALLFHSDAILKRLNIGDRDIKIGWGKPTRIDPIVAARISTDGATRNVYIGRMTIEGEESHLSEEQLRVDLEEYGEIDCIKIIKEKGIAFIHFASILNAIKVVTNLPIRNPYYQNKRIFYGKDRCAFITKTQQHNAAQFLGVQPGMEHMIEFSDREFISNALLQQSAAAAAIATSAGGPNNLGNRTVYLGSLPKDVKIEEICNAVRGGLLQSIKLLNDRYVCFVTFIDPTAAAQFYAMSSLYGFTVQKKRCKVGWGKHSGPLPNALALAVSNGASRNVYVGNIDFVGDSLRDERVFTESNLRHIFQQYGEVEQINFLPEKNCCFINYTNISNAILALDKIKSNPYFKDLKINFGKDRCGNVPHQSR
SIO_010081: YPL184C
subclass of: SO_0000673
so part of: YPL184C
location: complement(195950..197788)
location: region:195950-197788:-1
so has part: feature:195950-197788:-1:exon

NP_015140.1
type: Protein
SIO_000068: ncbiprotein

S000006105
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:195950-197788:-1:exon

YPL183W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL36m
alternative label: TAE4
gene: RTC6
locus tag: YPL183W-A
gene synonym: bL36m; TAE4
so part of: sequence
location: <199095..>199376
location: region:199095-199376:1
so has part: feature:199095-199376:1:exon
subclass of: SO_0000010

855918
type: Gene
SIO_000068: ncbigene

position:199095:1
position: 199095
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:199376:1
position: 199376
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199095-199376:1:exon

YPL183W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL36m
alternative label: TAE4
gene: RTC6
locus tag: YPL183W-A
gene synonym: bL36m; TAE4
product: putative mitochondrial 54S ribosomal protein RTC6
transcript id: NM_001184317.1
SIO_010081: YPL183W-A
subclass of: SO_0000673
so part of: YPL183W-A
location: <199095..>199376
location: region:199095-199376:1
so has part: feature:199095-199376:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199095-199376:1:exon

YPL183W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL36m
alternative label: TAE4
gene: RTC6
locus tag: YPL183W-A
gene synonym: bL36m; TAE4
experiment: EXISTENCE:genetic interaction:GO:0042254 ribosome biogenesis [PMID:20691087]
experiment: EXISTENCE:mutant phenotype:GO:0042254 ribosome biogenesis [PMID:20691087]
note: Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress
codon start: 1
product: putative mitochondrial 54S ribosomal protein RTC6
translation: MFLQTLRLTMPRMFLHMKPSPITITRACTVPSLLSVAAPQPALVAANRPLVFNRGFKVRTSVKKFCSDCYLVRRKGRVYIYCKSNKKHKQRQG
SIO_010081: YPL183W-A
subclass of: SO_0000673
so part of: YPL183W-A
location: 199095..199376
location: region:199095-199376:1
so has part: feature:199095-199376:1:exon

NP_015141.1
type: Protein
SIO_000068: ncbiprotein

S000007224
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199095-199376:1:exon

YPL183C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ERE2
alternative label: TRM734
gene: RTT10
locus tag: YPL183C
gene synonym: ERE2; TRM734
so part of: sequence
location: complement(<199495..>202536)
location: region:199495-202536:-1
so has part: feature:199495-202536:-1:exon
subclass of: SO_0000010

855919
type: Gene
SIO_000068: ncbigene

position:199495:-1
position: 199495
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:202536:-1
position: 202536
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199495-202536:-1:exon

YPL183C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ERE2
alternative label: TRM734
gene: RTT10
locus tag: YPL183C
gene synonym: ERE2; TRM734
product: Rtt10p
transcript id: NM_001183997.1
SIO_010081: YPL183C
subclass of: SO_0000673
so part of: YPL183C
location: complement(<199495..>202536)
location: region:199495-202536:-1
so has part: feature:199495-202536:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199495-202536:-1:exon

YPL183C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ERE2
alternative label: TRM734
gene: RTT10
locus tag: YPL183C
gene synonym: ERE2; TRM734
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:21880895|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:21880895]
experiment: EXISTENCE:mutant phenotype:GO:0002130 wobble position ribose methylation [PMID:22912484]
experiment: EXISTENCE:mutant phenotype:GO:0032456 endocytic recycling [PMID:21880895]
experiment: EXISTENCE:physical interaction:GO:0002130 wobble position ribose methylation [PMID:22912484]
note: WD40 domain-containing protein involved in endosomal recycling; forms a complex with Rrt2p that functions in the retromer-mediated pathway for recycling internalized cell-surface proteins; interacts with Trm7p for 2'-O-methylation of N34 of substrate tRNAs; has a role in regulation of Ty1 transposition; human ortholog is WDR6
codon start: 1
product: Rtt10p
translation: MKDLSHYGPALCVKFYNDYVLAGYGPFIHVYDYHSATLINKCRLFHYNKVHGLSLSSEGKILAYGARSVTIVELEDVLKKESLVDFERINSDWITGATFSFDNLQIYLLTCYNKVLICDLNCEVLFRKSLGGERSILYSGIIKVFGPDKVYVNAGTVMGGVIIWDLFSETKIHNLLGHEGSIFYVNLSNNGRYVASCSDDRSIRLWDLETGKQLSVGWSHTARIWNLMFFDNDSKLISVSEDCTCRVWNIIESRENVAELSISNVYEVHLIKSIWGVDVKDDEMIAVTSGNDGRLKLIDLLQLKRHGDEETSFSLDDIAKQCGDIFEKNESIKGFQWFSFGVIAITSLGKILKYSDVTKQWKLLLTNEKFNSYPITNGIQTQNIAVFSNNKSDILLIKFSKDSADIIETEEFHLDELSKTNNCLVTEYDDDSFLLTLQSPNPREKFVCLEISLQNLKIKSKHCFNKPENFSSSCLTSFRNHILVGSRFSTLVIYNLLDESEEPFIIRRLSPGDTTTSIEFVEDKDNSAVFSVTNRDGYYVFIELTKNSLEEGPYRLSYKVLHSNKMMKGFLEGAFFNSKGEYITYGFKSSLFYLYNETNCYELASEVCGGSHRLWNLAKITDGHVLMYIKASRFHLRKIYNSIVPETLENGVHGREIRDISICPVSNTNTNDNFKDGHIFCTASEDTTIKLGYFNNRTGKVQNFWTQRKHVSGLQRCQFINHKLMISSSAREELFLWELNDKYNKRPYMTIRQALPVSTNNSDLRIMDFDVKFISQSGDFLLVTVYSDSTIKIWHYRENQNKFDLIMQGRYKTCCLFNVVFIALKEELLVVISPTDGHLVVYNITEYVPFSVDPISGDLVDHKLDATISNLPAPVAQLPVHQSGVKSLDYVANATRTSATILTGGDDNGLGLSNLKLDDSNKVTLKTSDFIAAAASSTITSGMLINGGKEVITTSVDQVIRAWEITAGKLSLVDKKRTTVADTGSLEIISNDEDADSEKTLLIGGVGLSIWKK
SIO_010081: YPL183C
subclass of: SO_0000673
so part of: YPL183C
location: complement(199495..202536)
location: region:199495-202536:-1
so has part: feature:199495-202536:-1:exon

NP_015142.1
type: Protein
SIO_000068: ncbiprotein

S000006104
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199495-202536:-1:exon

YPL181W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RXT1
gene: CTI6
locus tag: YPL181W
gene synonym: RXT1
so part of: sequence
location: <203421..>204941
location: region:203421-204941:1
so has part: feature:203421-204941:1:exon
subclass of: SO_0000010

855920
type: Gene
SIO_000068: ncbigene

position:203421:1
position: 203421
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:204941:1
position: 204941
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203421-204941:1:exon

YPL181W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RXT1
gene: CTI6
locus tag: YPL181W
gene synonym: RXT1
product: Cti6p
transcript id: NM_001183995.1
SIO_010081: YPL181W
subclass of: SO_0000673
so part of: YPL181W
location: <203421..>204941
location: region:203421-204941:1
so has part: feature:203421-204941:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203421-204941:1:exon

YPL181W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RXT1
gene: CTI6
locus tag: YPL181W
gene synonym: RXT1
experiment: EXISTENCE:direct assay:GO:0033698 Rpd3L complex [PMID:16286007|PMID:16286008|PMID:16314178|PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0035064 methylated histone binding [PMID:17142463]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:19417103]
experiment: EXISTENCE:mutant phenotype:GO:0045893 positive regulation of DNA-templated transcription [PMID:12086626]
experiment: EXISTENCE:mutant phenotype:GO:0061186 negative regulation of silent mating-type cassette heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:0061188 negative regulation of rDNA heterochromatin formation [PMID:16286008]
note: Component of the Rpd3L histone deacetylase complex; relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain
codon start: 1
product: Cti6p
translation: MESTAIVPKGPVVGSEDMEKAEVIASGSTDIISTTSTATTTAAIGSVQEESVKQEDVPMEGGEGEVEEEEGETRCICGELDTPDDSGFFIQCEQCSSWQHGYCVSITQDNAPDKYWCEQCRPELHQLFTTDTGEARSIYKPVQEKRRQSRRKARSAAASKSHAANEAEKSPRNTSNTDDNVDDIGDEEDEVEDEASAVALAKDGNTRSSRRRRRNSMDDASTDQYSLDPGDSDKKLLDRKRATFMAREEKQYQRMLEKALKESRRTSHQEDPESYENDADIYQGDTDNHNGTTRLQTDVMLTEGKPDSVTNDDMKESLRPSKEQSMEKTNDVEKEASQEKESSTGSAQDTEKTDEPILPLTSISSSEDDSRKASSRGSKRVSKPARKGNRTRRSNTSSDTNQNRRSADIGTDKPVKPRLPPQRTSLNEMRRRVSAILEFISRTQWELSEDQSDREEFVRFVENQHFVEKVDTIYNGYNESLSMMDDLTRELLLWEKKYSNNTNAIQ
SIO_010081: YPL181W
subclass of: SO_0000673
so part of: YPL181W
location: 203421..204941
location: region:203421-204941:1
so has part: feature:203421-204941:1:exon

NP_015144.1
type: Protein
SIO_000068: ncbiprotein

S000006102
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203421-204941:1:exon

YPL180W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TCO89
locus tag: YPL180W
so part of: sequence
location: <205248..>207647
location: region:205248-207647:1
so has part: feature:205248-207647:1:exon
subclass of: SO_0000010

855922
type: Gene
SIO_000068: ncbigene

position:205248:1
position: 205248
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:207647:1
position: 207647
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205248-207647:1:exon

YPL180W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TCO89
locus tag: YPL180W
product: Tco89p
transcript id: NM_001183994.1
SIO_010081: YPL180W
subclass of: SO_0000673
so part of: YPL180W
location: <205248..>207647
location: region:205248-207647:1
so has part: feature:205248-207647:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:205248-207647:1:exon

YPL180W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TCO89
locus tag: YPL180W
experiment: EXISTENCE:curator inference:GO:0031929 TOR signaling [PMID:14736892]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:17560372|PMID:19748353|PMID:14562095|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006071 glycerol metabolic process [PMID:10931309]
experiment: EXISTENCE:mutant phenotype:GO:0009651 response to salt stress [PMID:17298473]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:14736892]
experiment: EXISTENCE:physical interaction:GO:0001558 regulation of cell growth [PMID:14736892]
experiment: EXISTENCE:physical interaction:GO:0031931 TORC1 complex [PMID:14736892]
note: Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p); regulates global H3K56ac; TORC1 complex regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin
codon start: 1
product: Tco89p
translation: MVHRGRTLKSDTDVTSLNASTVSHQSKPFRQFSTRSRAKSNASFKGLRRVLTHDGTLDNDYFNKHNVSQKCKSSDALFRKRTISGLNMTALTRVKSNQGKRSASFHSPVHNTLLSPKNSSHSNTGTAGFGLKPRRSKSTQSVLSLRDAQESKKSESTTDEEVECFSEDNIEDGKVNNDKVIAEHVMPEEKKNVQQLNQNELQSPDSIDEQEEDKSGTDGKENHRAVSLPLPHLSSNNYFGESSHSIEHQKDGETSPSSIETKLNATSVINEEGQSKVTKEADIDDLSSHSQNLRASLVKAGDNISEAPYDKEKKILDVGNTLAAHKSNQKPSHSDEQFDQEDHIDAPRSNSSRKSDSSFMSLRRQSSKQHKLLNEEEDLIKPDDISSAGTKDIEGHSLLENYAPNMILSQSTGVERRFENSSSIQNSLGNEIHDSGEHMASGDTFNELDDGKLRKSKKNGGRSQLGQNIPNSQSTFPTIANIGSKDNNVPQHNFSTSISSLTNNLRRAAPESFHGSRMNNIFHKKGNQNLLLRSNDLNKNSAAPASPLSNEHITSSTNSGSDANRQSNSGAKFNSFAQFLKSDGIDAESRTQRKLWLQRENSIMDLSSQNDGSDSIFMAGNIDAKREFERISHEYSNVKRFYNPLDEALLRVQPIITGNANNIRKKSHNDAQSIAHSSSDTDHKDEDDLLFTNYDKKFDDLYPHLASAKIQAVLSGIWKSESYLFNKDVNPINKNRTTSTNHSVGHTASQNARNLLRGPMGSSTTLHHQRVINSLQPTTRAVNRRMENVGYMHTQPQQR
SIO_010081: YPL180W
subclass of: SO_0000673
so part of: YPL180W
location: 205248..207647
location: region:205248-207647:1
so has part: feature:205248-207647:1:exon

NP_015145.1
type: Protein
SIO_000068: ncbiprotein

S000006101
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:205248-207647:1:exon

YPL179W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SAL6
gene: PPQ1
locus tag: YPL179W
gene synonym: SAL6
so part of: sequence
location: <208157..>209806
location: region:208157-209806:1
so has part: feature:208157-209806:1:exon
subclass of: SO_0000010

855923
type: Gene
SIO_000068: ncbigene

position:208157:1
position: 208157
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:209806:1
position: 209806
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:208157-209806:1:exon

YPL179W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SAL6
gene: PPQ1
locus tag: YPL179W
gene synonym: SAL6
product: protein-serine/threonine phosphatase
transcript id: NM_001183993.1
SIO_010081: YPL179W
subclass of: SO_0000673
so part of: YPL179W
location: <208157..>209806
location: region:208157-209806:1
so has part: feature:208157-209806:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:208157-209806:1:exon

YPL179W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SAL6
gene: PPQ1
locus tag: YPL179W
gene synonym: SAL6
EC number: 3.1.3.16
experiment: EXISTENCE:direct assay:GO:0004721 phosphoprotein phosphatase activity [PMID:24309106]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0090029 negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:24309106]
note: Protein phosphatase that regulates the mating response; negatively regulates the MAP kinase signaling cascade during mating; member of the serine/threonine phosphatase PP1 family
codon start: 1
product: protein-serine/threonine phosphatase
translation: MRRSPSRSNNNFAVPNCSTNSNSSQQQLTTPSDDLNSNEPNDPDDSRSLPTIKKFNNKHSINNYNTLASAGKNNNNKRASNDNLLIPGENAHKQKIYTKDENLKSLYLDIDVSVAKALSSSATAPKLINTARTSSTTTATTSNNILTSPSYRESNYSSPSSYSFSSYYSSATSASSSTSSFLKSSGLSSRVKSPSSSVKAGSFGAPSSPTSGIPNPKSSKKPIFLRRYSHDTSSNEGLDIDVAIEKLLQVGESREITKTSKKKNFPFHSWEIQLICYHAREIFLNQPTLLRLQAPIKVVGDVHGQFNDLLRILKLSGVPSDTNYLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMYGFYDECKRRLSSKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARPTDIPESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEFFARKKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKPRALKNKKKLYKTKV
SIO_010081: YPL179W
subclass of: SO_0000673
so part of: YPL179W
location: 208157..209806
location: region:208157-209806:1
so has part: feature:208157-209806:1:exon

NP_015146.1
type: Protein
SIO_000068: ncbiprotein

S000006100
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:208157-209806:1:exon

YNCP0004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0004C
so part of: sequence
location: complement(210192..210263)
location: region:210192-210263:-1
so has part: feature:210192-210263:-1:exon
subclass of: SO_0000663

855924
type: Gene
SIO_000068: ncbigene

position:210192:-1
position: 210192
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:210263:-1
position: 210263
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210192-210263:-1:exon

YNCP0004C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0004C
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; target of K. lactis zymocin
SIO_010081: YNCP0004C
subclass of: SO_0000673
so part of: YNCP0004C
location: complement(210192..210263)
location: region:210192-210263:-1
so has part: feature:210192-210263:-1:exon

S000006561
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210192-210263:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 210451..210771
location: region:210451-210771:1
so has part: feature:210451-210771:1:region

S000007194
type: SGD
SIO_000068: sgd

position:210451:1
position: 210451
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:210771:1
position: 210771
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210451-210771:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 211577..211898
location: region:211577-211898:1
so has part: feature:211577-211898:1:region

S000007195
type: SGD
SIO_000068: sgd

position:211577:1
position: 211577
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:211898:1
position: 211898
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:211577-211898:1:region

YPL178W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CBP20
alternative label: MUD13
alternative label: SAE1
gene: CBC2
locus tag: YPL178W
gene synonym: CBP20; MUD13; SAE1
so part of: sequence
location: <212158..>212784
location: region:212158-212784:1
so has part: feature:212158-212784:1:exon
subclass of: SO_0000010

855925
type: Gene
SIO_000068: ncbigene

position:212158:1
position: 212158
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:212784:1
position: 212784
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:212158-212784:1:exon

YPL178W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CBP20
alternative label: MUD13
alternative label: SAE1
gene: CBC2
locus tag: YPL178W
gene synonym: CBP20; MUD13; SAE1
product: nuclear cap-binding protein subunit CBC2
transcript id: NM_001183992.1
SIO_010081: YPL178W
subclass of: SO_0000673
so part of: YPL178W
location: <212158..>212784
location: region:212158-212784:1
so has part: feature:212158-212784:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:212158-212784:1:exon

YPL178W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CBP20
alternative label: MUD13
alternative label: SAE1
gene: CBC2
locus tag: YPL178W
gene synonym: CBP20; MUD13; SAE1
experiment: EXISTENCE:direct assay:GO:0000243 commitment complex [PMID:8682299]
experiment: EXISTENCE:direct assay:GO:0000339 RNA cap binding [PMID:8682299]
experiment: EXISTENCE:direct assay:GO:0005846 nuclear cap binding complex [PMID:8811086]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:8682299]
note: Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif
codon start: 1
product: nuclear cap-binding protein subunit CBC2
translation: MSLEEFDEVKYDHSTKRLDTPSRYLLRKARRNPNGLQELRESMKSSTIYVGNLSFYTSEEQIYELFSKCGTIKRIIMGLDRFKFTPCGFCFIIYSCPDEALNALKYLSDTKLDEKTITIDLDPGFEDGRQFGRGKSGGQVSDELRFDFDASRGGFAIPFAERVGVPHSRFDNSSSQSNTNNYIPPPDAMGTFRPGFDEEREDDNYVPQ
SIO_010081: YPL178W
subclass of: SO_0000673
so part of: YPL178W
location: 212158..212784
location: region:212158-212784:1
so has part: feature:212158-212784:1:exon

NP_015147.1
type: Protein
SIO_000068: ncbiprotein

S000006099
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:212158-212784:1:exon

YPL177C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CUP9
locus tag: YPL177C
so part of: sequence
location: complement(<213042..>213962)
location: region:213042-213962:-1
so has part: feature:213042-213962:-1:exon
subclass of: SO_0000010

855926
type: Gene
SIO_000068: ncbigene

position:213042:-1
position: 213042
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:213962:-1
position: 213962
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:213042-213962:-1:exon

YPL177C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CUP9
locus tag: YPL177C
product: Cup9p
transcript id: NM_001183991.1
SIO_010081: YPL177C
subclass of: SO_0000673
so part of: YPL177C
location: complement(<213042..>213962)
location: region:213042-213962:-1
so has part: feature:213042-213962:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:213042-213962:-1:exon

YPL177C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CUP9
locus tag: YPL177C
experiment: EXISTENCE:curator inference:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:18708352|PMID:9427760]
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:9427760]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:9427760]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:10850718|PMID:17005992|PMID:18708352|PMID:9427760]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:18708352]
note: Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
codon start: 1
product: Cup9p
translation: MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN
SIO_010081: YPL177C
subclass of: SO_0000673
so part of: YPL177C
location: complement(213042..213962)
location: region:213042-213962:-1
so has part: feature:213042-213962:-1:exon

NP_015148.1
type: Protein
SIO_000068: ncbiprotein

S000006098
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:213042-213962:-1:exon

YPL176C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRE1
locus tag: YPL176C
so part of: sequence
location: complement(<216012..>218363)
location: region:216012-218363:-1
so has part: feature:216012-218363:-1:exon
subclass of: SO_0000010

855927
type: Gene
SIO_000068: ncbigene

position:216012:-1
position: 216012
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:218363:-1
position: 218363
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216012-218363:-1:exon

YPL176C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TRE1
locus tag: YPL176C
product: Tre1p
transcript id: NM_001183990.1
SIO_010081: YPL176C
subclass of: SO_0000673
so part of: YPL176C
location: complement(<216012..>218363)
location: region:216012-218363:-1
so has part: feature:216012-218363:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:216012-218363:-1:exon

YPL176C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TRE1
locus tag: YPL176C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:16456538|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:19369420]
note: Transferrin receptor-like protein; plasma membrane protein that binds Bsd2p and regulates ubiquitination and vacuolar degradation of the metal transporter Smf1p; functionally redundant with Tre2p; TRE1 has a paralog, TRE2, that arose from the whole genome duplication
codon start: 1
product: Tre1p
translation: MVNTRGYTTLPNVEEPANNSQDELNSQDFEQAIGMPSEPPVYVEEMGMEEPQAPEAFSEKVQRFRMCFENNVVIPVKKNVVDPLAQMISLASEKFDLFLSKIGNVMVMRRIFYIMMMSIIAALIIASDRLPNGKARGSNGSFSDHDLLLQYARKSIDLSKIERDLEYISSMPHMSGTSGDAAIRHYIKESFDKNGIRLAGEEEFMAYSNYPGNVSLRVYSKDDTEGFDIPLNEENFNPMSHNGQLNNIPVIYANKASLDDMASMQDQGLLNGDFILLVHYGDYVFQQMLTAQEYGAKAIIFISEPYQDNKDVIQMKSVALPQYGTGDALTPEWEGSIRDPIDATEAKCLPKIPSIPISANQGDKILAILSDTGVKFSNNLFSGSLNDCRLDLLVQTAIRERHPVHDIVGKIEGSEQAGRAIVIAAPRNSASYGTMYPSFGTVVLLSLIQLYQEMVYKFDWKPLRNIYFISFGGSEFNEAGATELMEKRTEALKSEIYTIIDVGQIGIWDDSNNLEIQCHPLLVDLFQKNMTSRKFNVKVDNVHQFGDWTPYLAQGIPVAIISSPGVMNREHPIYTVEDKFDFIKDKLRDKKKGEVLSEIMLYLVEKSLELIDDPFIPFSISNYVDFLSTTLKDLQKECPDTVNFDEVFLGTTLWENTKLQFEKWKSEWTELMYGAGTYIEPTIIAINRWSWNYLLSLIGVTQCLEEGLMDRTFYKNVIFGPKLWVDKGDPLRSWTFPEIRDTIAIKDWSSVQVQANTLGTILQNTARYFLENKNLHGINTNEF
SIO_010081: YPL176C
subclass of: SO_0000673
so part of: YPL176C
location: complement(216012..218363)
location: region:216012-218363:-1
so has part: feature:216012-218363:-1:exon

NP_015149.1
type: Protein
SIO_000068: ncbiprotein

S000006097
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:216012-218363:-1:exon

YPL175W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CWH6
alternative label: GPI3
gene: SPT14
locus tag: YPL175W
gene synonym: CWH6; GPI3
so part of: sequence
location: <218630..>220088
location: region:218630-220088:1
so has part: feature:218630-220088:1:exon
subclass of: SO_0000010

855928
type: Gene
SIO_000068: ncbigene

position:218630:1
position: 218630
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220088:1
position: 220088
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:218630-220088:1:exon

YPL175W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CWH6
alternative label: GPI3
gene: SPT14
locus tag: YPL175W
gene synonym: CWH6; GPI3
product: phosphatidylinositol N-acetylglucosaminyltransferase SPT14
transcript id: NM_001183989.1
SIO_010081: YPL175W
subclass of: SO_0000673
so part of: YPL175W
location: join(<218630..218646,218747..>220088)
location: region:218630-220088:1
so has part: feature:218630-218646:1:exon
so has part: feature:218747-220088:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:218630-218646:1:exon

position:218646:1
position: 218646
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:218747-220088:1:exon

position:218747:1
position: 218747
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL175W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CWH6
alternative label: GPI3
gene: SPT14
locus tag: YPL175W
gene synonym: CWH6; GPI3
EC number: 2.4.1.198
experiment: EXISTENCE:curator inference:GO:0006506 GPI anchor biosynthetic process [PMID:10970797]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005783 endoplasmic reticulum [PMID:9079905]
experiment: EXISTENCE:mutant phenotype:GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity [PMID:10970797]
note: UDP-glycosyltransferase subunit of the GPI-GnT complex; UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins
codon start: 1
product: phosphatidylinositol N-acetylglucosaminyltransferase SPT14
translation: MGFNIAMLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHVPFFVIFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFTDHSLYGFNNLTSIWVNKLLTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVVSEDFKPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGDGPKFIDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASCNLLIVTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKALDTSSFHDSVSKMYDWMDVAKRTVEIYTNISSTSSADDKDWMKMVANLYKRDGIWAKHLYLLCGIVEYMLFFLLEWLYPRDEIDLAPKWPKKTVSNETKEARET
SIO_010081: YPL175W
subclass of: SO_0000673
so part of: YPL175W
location: join(218630..218646,218747..220088)
location: region:218630-220088:1
so has part: feature:218630-218646:1:exon
so has part: feature:218747-220088:1:exon

NP_015150.2
type: Protein
SIO_000068: ncbiprotein

S000006096
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:218630-218646:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:218747-220088:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1611; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 220088..220167
location: region:220088-220167:1
so has part: feature:220088-220167:1:region

S000130197
type: SGD
SIO_000068: sgd

position:220167:1
position: 220167
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220088-220167:1:region

YPL174C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PAC13
gene: NIP100
locus tag: YPL174C
gene synonym: PAC13
so part of: sequence
location: complement(<220167..>222773)
location: region:220167-222773:-1
so has part: feature:220167-222773:-1:exon
subclass of: SO_0000010

855929
type: Gene
SIO_000068: ncbigene

position:220167:-1
position: 220167
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:222773:-1
position: 222773
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220167-222773:-1:exon

YPL174C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PAC13
gene: NIP100
locus tag: YPL174C
gene synonym: PAC13
product: Nip100p
transcript id: NM_001183988.1
SIO_010081: YPL174C
subclass of: SO_0000673
so part of: YPL174C
location: complement(<220167..>222773)
location: region:220167-222773:-1
so has part: feature:220167-222773:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:220167-222773:-1:exon

YPL174C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PAC13
gene: NIP100
locus tag: YPL174C
gene synonym: PAC13
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:9658168]
experiment: EXISTENCE:direct assay:GO:0005869 dynactin complex [PMID:9658168]
experiment: EXISTENCE:mutant phenotype:GO:0000132 establishment of mitotic spindle orientation [PMID:9658168]
note: Large subunit of the dynactin complex; dynactin is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)
codon start: 1
product: Nip100p
translation: MRNAGVQVDTNMQKISLQDTVLVNEMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYGLFCKKDTLQFYKPDDDEHSLLNGNAAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQTKLSYDKAMKVQEDLLEENTQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSKSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDENLRITYEQLEQELRLQLSNLQSALENEKEIAGTYIEENSRLKATLESIEAKTSHKFQSLELKVNTLQEELYQNKLLKKFYQIYEPFAQPHLAALSSQLQYLAEVIESENFGKLENIEIHIILKVLSSISYALHIYTIKNTPDHLETTLQCFKVNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKFLDKDVTLILKILHPILETTVPKLLAFLRTNSNFNDNDTLCLIGSLYERSLSLIARIDKLIGKEEISKQDNRLFLYPSCDITLSSILTILFSDALFLRQDYKRISSLKKLEVFFQGIESLLENITIFPEQPSQQTSDSESQCNIKEGNFSNSLLSDRLNEENIRLKEVLVQKENMLTELETKIKIIIGRDLERKTLEENIKTLKVELNNKNEENCGKTEILNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKIYLDREKVDRVNLVSEIMELRETIRRQIKEQKRVSIDFSWLDELPAVENKQPFKEHINHSLDTLGIEMFNFVSTSRILDLKLDQPLAEDELWHERDHSYISYLKRKRKNIRLKSQNVVTYYK
SIO_010081: YPL174C
subclass of: SO_0000673
so part of: YPL174C
location: complement(220167..222773)
location: region:220167-222773:-1
so has part: feature:220167-222773:-1:exon

NP_015151.1
type: Protein
SIO_000068: ncbiprotein

S000006095
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:220167-222773:-1:exon

YPL173W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: uL24m
gene: MRPL40
locus tag: YPL173W
gene synonym: uL24m
so part of: sequence
location: <223143..>224036
location: region:223143-224036:1
so has part: feature:223143-224036:1:exon
subclass of: SO_0000010

855930
type: Gene
SIO_000068: ncbigene

position:223143:1
position: 223143
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:224036:1
position: 224036
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:223143-224036:1:exon

YPL173W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: uL24m
gene: MRPL40
locus tag: YPL173W
gene synonym: uL24m
product: mitochondrial 54S ribosomal protein YmL40
transcript id: NM_001183987.1
SIO_010081: YPL173W
subclass of: SO_0000673
so part of: YPL173W
location: <223143..>224036
location: region:223143-224036:1
so has part: feature:223143-224036:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:223143-224036:1:exon

YPL173W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: uL24m
gene: MRPL40
locus tag: YPL173W
gene synonym: uL24m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552|PMID:9151978]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552|PMID:9151978]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552|PMID:9151978]
note: Mitochondrial ribosomal protein of the large subunit
codon start: 1
product: mitochondrial 54S ribosomal protein YmL40
translation: MSGSYQHLSNVGSRVMKRLGNRPKNFLPHSEKFIKKSTPEFMKSDLKEVDEKTSFKSEKEWKFIPGDRVVVMSGASKGNIAVIKSFDKRTNSFILDENGPTKTVPVPKQFWLEGQTSHMITIPVSILGKDLRLVADIDDEKTPGKTRTVAVRDVSFNGSYYDADYKKVMPYRCVKGQPDLIIPWPKPDPIDVQTNLATDPVIAREQTFWVDSVVRNPIPKKAIPSIRNPHSKYKRGTLTAKDIAKLVAPEMPLTEVRKSHLAEKKELAEREVPKLTEEDMEAIGARVFEFLEKQKRE
SIO_010081: YPL173W
subclass of: SO_0000673
so part of: YPL173W
location: 223143..224036
location: region:223143-224036:1
so has part: feature:223143-224036:1:exon

NP_015152.1
type: Protein
SIO_000068: ncbiprotein

S000006094
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:223143-224036:1:exon

YPL172C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COX10
locus tag: YPL172C
so part of: sequence
location: complement(<224353..>225741)
location: region:224353-225741:-1
so has part: feature:224353-225741:-1:exon
subclass of: SO_0000010

855931
type: Gene
SIO_000068: ncbigene

position:224353:-1
position: 224353
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:225741:-1
position: 225741
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:224353-225741:-1:exon

YPL172C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COX10
locus tag: YPL172C
product: protoheme IX farnesyltransferase
transcript id: NM_001183986.1
SIO_010081: YPL172C
subclass of: SO_0000673
so part of: YPL172C
location: complement(<224353..>225741)
location: region:224353-225741:-1
so has part: feature:224353-225741:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:224353-225741:-1:exon

YPL172C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COX10
locus tag: YPL172C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278]
experiment: EXISTENCE:mutant phenotype:GO:0006784 heme A biosynthetic process [PMID:8118433]
note: Heme A:farnesyltransferase; catalyzes first step in conversion of protoheme to heme A prosthetic group required for cytochrome c oxidase activity; human ortholog COX10 can complement yeast cox10 null mutant; human ortholog COX10 is associated with mitochondrial disorders
codon start: 1
product: protoheme IX farnesyltransferase
translation: MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGKQQHINTAPIEFTPNFGYGDRTSNCNKKVESTAMKTLRCTDDISTSSGSEATTDASTQLPFNVKLVDPMVRKSKRPSHAISEGLNMKTLKKKVIMPYLQLTKPRLTILVMLSAICSYALSPYPASVNELLCLTVGTTLCSGSANAINMGREPEFDRQMVRTQARPVVRGDVTPTQAFEFAALIGTLGVSILYFGVNPTVAILGASNIALYGWAYTSMKRKHIINTWLGALVGMVPPLMGWAAASPLSHPGSWCLAGLLFAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPLLNARVSLRYSILMFPLCFGLSYFNITDWYYQIDSGLINAWLTFWAFKFYWQQRINYSAKTLKDNVKFNKGLSVANIYARKTFMASVLHLPAILILAIIHKKGRWDWIYPGEAKRPQERF
SIO_010081: YPL172C
subclass of: SO_0000673
so part of: YPL172C
location: complement(224353..225741)
location: region:224353-225741:-1
so has part: feature:224353-225741:-1:exon

NP_015153.1
type: Protein
SIO_000068: ncbiprotein

S000006093
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:224353-225741:-1:exon

YPL171C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ZRG6
gene: OYE3
locus tag: YPL171C
gene synonym: ZRG6
so part of: sequence
location: complement(<226169..>227371)
location: region:226169-227371:-1
so has part: feature:226169-227371:-1:exon
subclass of: SO_0000010

855932
type: Gene
SIO_000068: ncbigene

position:226169:-1
position: 226169
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:227371:-1
position: 227371
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226169-227371:-1:exon

YPL171C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ZRG6
gene: OYE3
locus tag: YPL171C
gene synonym: ZRG6
product: NADPH dehydrogenase
transcript id: NM_001183985.1
SIO_010081: YPL171C
subclass of: SO_0000673
so part of: YPL171C
location: complement(<226169..>227371)
location: region:226169-227371:-1
so has part: feature:226169-227371:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:226169-227371:-1:exon

YPL171C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ZRG6
gene: OYE3
locus tag: YPL171C
gene synonym: ZRG6
EC number: 1.6.99.1
experiment: EXISTENCE:direct assay:GO:0003959 NADPH dehydrogenase activity [PMID:7836424]
experiment: EXISTENCE:mutant phenotype:GO:0006915 apoptotic process [PMID:17897954]
note: Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN); homologous to Oye2p with different ligand binding and catalytic properties; has potential roles in oxidative stress response and programmed cell death
codon start: 1
product: NADPH dehydrogenase
translation: MPFVKGFEPISLRDTNLFEPIKIGNTQLAHRAVMPPLTRMRATHPGNIPNKEWAAVYYGQRAQRPGTMIITEGTFISPQAGGYDNAPGIWSDEQVAEWKNIFLAIHDCQSFAWVQLWSLGWASFPDVLARDGLRYDCASDRVYMNATLQEKAKDANNLEHSLTKDDIKQYIKDYIHAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNKRTDEYGGTIENRARFTLEVVDALIETIGPERVGLRLSPYGTFNSMSGGAEPGIIAQYSYVLGELEKRAKAGKRLAFVHLVEPRVTDPSLVEGEGEYSEGTNDFAYSIWKGPIIRAGNYALHPEVVREQVKDPRTLIGYGRFFISNPDLVYRLEEGLPLNKYDRSTFYTMSAEGYTDYPTYEEAVDLGWNKN
SIO_010081: YPL171C
subclass of: SO_0000673
so part of: YPL171C
location: complement(226169..227371)
location: region:226169-227371:-1
so has part: feature:226169-227371:-1:exon

NP_015154.1
type: Protein
SIO_000068: ncbiprotein

S000006092
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:226169-227371:-1:exon

YPL170W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DAP1
locus tag: YPL170W
so part of: sequence
location: <228314..>228772
location: region:228314-228772:1
so has part: feature:228314-228772:1:exon
subclass of: SO_0000010

855933
type: Gene
SIO_000068: ncbigene

position:228314:1
position: 228314
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:228772:1
position: 228772
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:228314-228772:1:exon

YPL170W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DAP1
locus tag: YPL170W
product: Dap1p
transcript id: NM_001183984.1
SIO_010081: YPL170W
subclass of: SO_0000673
so part of: YPL170W
location: <228314..>228772
location: region:228314-228772:1
so has part: feature:228314-228772:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:228314-228772:1:exon

YPL170W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DAP1
locus tag: YPL170W
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:17954932]
experiment: EXISTENCE:direct assay:GO:0020037 heme binding [PMID:15713626]
experiment: EXISTENCE:genetic interaction:GO:0032443 regulation of ergosterol biosynthetic process [PMID:15713626]
experiment: EXISTENCE:mutant phenotype:GO:0032443 regulation of ergosterol biosynthetic process [PMID:17954932]
note: Heme-binding protein; involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
codon start: 1
product: Dap1p
translation: MSFIKNLLFGGVKTSEDPTGLTGNGASNTNDSNKGSEPVVAGNFFPRTLSKFNGHDDEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIPEPGVNV
SIO_010081: YPL170W
subclass of: SO_0000673
so part of: YPL170W
location: 228314..228772
location: region:228314-228772:1
so has part: feature:228314-228772:1:exon

NP_015155.1
type: Protein
SIO_000068: ncbiprotein

S000006091
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:228314-228772:1:exon

YPL169C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MEX67
locus tag: YPL169C
so part of: sequence
location: complement(<229039..>230838)
location: region:229039-230838:-1
so has part: feature:229039-230838:-1:exon
subclass of: SO_0000010

855934
type: Gene
SIO_000068: ncbigene

position:229039:-1
position: 229039
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:230838:-1
position: 230838
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:229039-230838:-1:exon

YPL169C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MEX67
locus tag: YPL169C
product: Mex67p
transcript id: NM_001183983.1
SIO_010081: YPL169C
subclass of: SO_0000673
so part of: YPL169C
location: complement(<229039..>230838)
location: region:229039-230838:-1
so has part: feature:229039-230838:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:229039-230838:-1:exon

YPL169C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MEX67
locus tag: YPL169C
experiment: EXISTENCE:direct assay:GO:0000049 tRNA binding [PMID:29212662]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:12524544]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:31753862]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0015288 porin activity [PMID:31753862]
experiment: EXISTENCE:direct assay:GO:0017070 U6 snRNA binding [PMID:31189105]
experiment: EXISTENCE:direct assay:GO:0030619 U1 snRNA binding [PMID:31189105]
experiment: EXISTENCE:direct assay:GO:0030620 U2 snRNA binding [PMID:31189105]
experiment: EXISTENCE:direct assay:GO:0030621 U4 snRNA binding [PMID:31189105]
experiment: EXISTENCE:direct assay:GO:0030623 U5 snRNA binding [PMID:31189105]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:31753862]
experiment: EXISTENCE:genetic interaction:GO:0000055 ribosomal large subunit export from nucleus [PMID:17434126]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:17434126|PMID:31439809]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:22956913]
experiment: EXISTENCE:mutant phenotype:GO:0006406 mRNA export from nucleus [PMID:10722667]
experiment: EXISTENCE:mutant phenotype:GO:0006409 tRNA export from nucleus [PMID:29212662]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:29212662]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:27385342]
experiment: EXISTENCE:mutant phenotype:GO:0051168 nuclear export [PMID:31189105]
experiment: EXISTENCE:mutant phenotype:GO:0071528 tRNA re-export from nucleus [PMID:33074312]
experiment: EXISTENCE:physical interaction:GO:0042272 nuclear RNA export factor complex [PMID:9774696]
note: Poly(A)RNA binding protein involved in nuclear mRNA export; component of the nuclear pore and nuclear RNA export factor; ubiquitin-associated (UBA) domain interacts with Mip6p; ortholog of human TAP
codon start: 1
product: Mex67p
translation: MSGFHNVGNINMMAQQQMQQNRIKISVRNWQNATMNDLINFISRNARVAVYDAHVEGPLVIGYVNSKAEAESLMKWNGVRFAGSNLKFELLDNNGASAGTSDTISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVFSSISTQSKMFPAMMKLASTEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSLEVWKNKFKDLRELLMTNNPITTDKLYRTEMLRLFPKLVVLDNVIVRDEQKLQTVYSLPMKIQQFFFENDALGQSSTDFATNFLNLWDNNREQLLNLYSPQSQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSSEKSIQQRLSIGQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEETGKPELESNKKTGKNNYQKNRRYNHGYNSTSNNKLSKKSFDRTWVIVPMNNSVIIASDLLTVRAYSTGAWKTASIAIAQPPQQQASVLPQVASMNPNITTPPQPQPSVVPGGMSIPGAPQGAMVMAPTLQLPPDVQSRLNPVQLELLNKLHLETKLNAEYTFMLAEQSNWNYEVAIKGFQSSMNGIPREAFVQF
SIO_010081: YPL169C
subclass of: SO_0000673
so part of: YPL169C
location: complement(229039..230838)
location: region:229039-230838:-1
so has part: feature:229039-230838:-1:exon

NP_015156.1
type: Protein
SIO_000068: ncbiprotein

S000006090
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:229039-230838:-1:exon

YPL168W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX4
locus tag: YPL168W
so part of: sequence
location: <231217..>232509
location: region:231217-232509:1
so has part: feature:231217-232509:1:exon
subclass of: SO_0000010

855935
type: Gene
SIO_000068: ncbigene

position:231217:1
position: 231217
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:232509:1
position: 232509
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:231217-232509:1:exon

YPL168W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX4
locus tag: YPL168W
product: Mrx4p
transcript id: NM_001183982.1
SIO_010081: YPL168W
subclass of: SO_0000673
so part of: YPL168W
location: <231217..>232509
location: region:231217-232509:1
so has part: feature:231217-232509:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:231217-232509:1:exon

YPL168W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX4
locus tag: YPL168W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
note: Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated
codon start: 1
product: Mrx4p
translation: MTVLYTSASLKKMKCLAFNMGMNCVRTVSHARSGGAKFGGRNVFNIFDSKTPDSVRIKAFKNTIYQSAMGKGKTKFSAMEINLITSLVRGYKGEGKKNAINPLQTNVQILNKLLLTHRLTDKDILEGMNLAAGPVNVAIPRDITPQEEKKKVELRNRKAENMDLHPSRKMHIKELLHSLNLDMCNDEEVYQKISLYLQKNEESRTSVGASQQNHVDIDINSLKRYLQNIEKKARQKSAIDKQKKNQARIYQWNTQSFSEIVPLSAGNILFKREPNRLWKRLQNGISVFLGSNGGGKKSKTTKKVLQGNNILLHSLENNKDMTLSNNFDHSVFNINFTDLFGVINASGSPPDRVLNEINEIELKGWKCVGNLYDNNKIVVFQSSNPLLEDTKIPQKSFTNSKRFLISLSALLASFFAYYRYRLSQRQESKK
SIO_010081: YPL168W
subclass of: SO_0000673
so part of: YPL168W
location: 231217..232509
location: region:231217-232509:1
so has part: feature:231217-232509:1:exon

NP_015157.1
type: Protein
SIO_000068: ncbiprotein

S000006089
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:231217-232509:1:exon

YPL167C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PSO1
gene: REV3
locus tag: YPL167C
gene synonym: PSO1
so part of: sequence
location: complement(<232593..>237107)
location: region:232593-237107:-1
so has part: feature:232593-237107:-1:exon
subclass of: SO_0000010

855936
type: Gene
SIO_000068: ncbigene

position:232593:-1
position: 232593
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:237107:-1
position: 237107
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:232593-237107:-1:exon

YPL167C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PSO1
gene: REV3
locus tag: YPL167C
gene synonym: PSO1
product: DNA-directed DNA polymerase
transcript id: NM_001183981.1
SIO_010081: YPL167C
subclass of: SO_0000673
so part of: YPL167C
location: complement(<232593..>237107)
location: region:232593-237107:-1
so has part: feature:232593-237107:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:232593-237107:-1:exon

YPL167C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PSO1
gene: REV3
locus tag: YPL167C
gene synonym: PSO1
EC number: 2.7.7.7
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:8658138]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16452144]
experiment: EXISTENCE:direct assay:GO:0016035 zeta DNA polymerase complex [PMID:8658138|PMID:22711820|PMID:23066099]
experiment: EXISTENCE:direct assay:GO:0042276 error-prone translesion synthesis [PMID:11313481|PMID:17248528]
experiment: EXISTENCE:direct assay:GO:0070987 error-free translesion synthesis [PMID:12514101]
experiment: EXISTENCE:genetic interaction:GO:0042276 error-prone translesion synthesis [PMID:9765213]
note: Catalytic subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; may be involved in meiosis; forms a complex with Rev7p, Pol31p and Pol32p
codon start: 1
product: DNA-directed DNA polymerase
translation: MSRESNDTIQSDTVRSSSKSDYFRIQLNNQDYYMSKPTFLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCHVHGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNLNFVADVSVVKGIPFYGYHVGWNLFYKISLLNPSCLSRISELIRDGKIFGKKFEIYESHIPYLLQWTADFNLFGCSWINVDRCYFRSPVLNSILDIDKLTINDDLQLLLDRFCDFKCNVLSRRDFPRVGNGLIEIDILPQFIKNREKLQHRDIHHDFLEKLGDISDIPVKPYVSSARDMINELTMQREELSLKEYKEPPETKRHVSGHQWQSSGEFEAFYKKAQHKTSTFDGQIPNFENFIDKNQKFSAINTPYEALPQLWPRLPQIEINNNSMQDKKNDDQVNASFTEYEICGVDNENEGVKGSNIKSRSYSWLPESIASPKDSTILLDHQTKYHNTINFSMDCAMTQNMASKRKLRSSVSANKTSLLSRKRKKVMAAGLRYGKRAFVYGEPPFGYQDILNKLEDEGFPKIDYKDPFFSNPVDLENKPYAYAGKRFEISSTHVSTRIPVQFGGETVSVYNKPTFDMFSSWKYALKPPTYDAVQKWYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKKSSVHDSLTHLTLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEGIMIVHKASEDSTFPTKIQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDIVRELARVKCQIKTKLSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGRVREINLTENNLGVSKFSLPRNILALLKNDVTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVYLPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSKRASTTTTKVENITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEALISLNDW
SIO_010081: YPL167C
subclass of: SO_0000673
so part of: YPL167C
location: complement(232593..237107)
location: region:232593-237107:-1
so has part: feature:232593-237107:-1:exon

NP_015158.1
type: Protein
SIO_000068: ncbiprotein

S000006088
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:232593-237107:-1:exon

YPL166W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATG29
locus tag: YPL166W
so part of: sequence
location: <237338..>237979
location: region:237338-237979:1
so has part: feature:237338-237979:1:exon
subclass of: SO_0000010

855937
type: Gene
SIO_000068: ncbigene

position:237338:1
position: 237338
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:237979:1
position: 237979
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237338-237979:1:exon

YPL166W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATG29
locus tag: YPL166W
product: Atg29p
transcript id: NM_001183980.1
SIO_010081: YPL166W
subclass of: SO_0000673
so part of: YPL166W
location: <237338..>237979
location: region:237338-237979:1
so has part: feature:237338-237979:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237338-237979:1:exon

YPL166W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATG29
locus tag: YPL166W
experiment: EXISTENCE:direct assay:GO:0000045 autophagosome assembly [PMID:18725539]
experiment: EXISTENCE:direct assay:GO:0000149 SNARE binding [PMID:26774783]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:16289106]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0034497 protein localization to phagophore assembly site [PMID:26774783]
experiment: EXISTENCE:direct assay:GO:1990316 Atg1/ULK1 kinase complex [PMID:26753620]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:16289106]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0044805 late nucleophagy [PMID:22768199]
note: Autophagy-specific protein; required for recruiting other ATG proteins to the pre-autophagosomal structure (PAS); interacts with Atg17p and localizas to the PAS in a manner interdependent with Atg17p and Cis1p; not conserved; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
codon start: 1
product: Atg29p
translation: MIMNSTNTVVYIKVKGRRPQGFLDPPKFEWNGTKERQLWTMVSNLNYSQDQIDWQNLSKIFETPEFFLKKRTYKLFAEHLELLQLQLEKKRDLEKYSNDQVNEGMSDLIHKYTPTLQNDNLLNVSASPLTTERQDSEEVETEVTNEALQHLQTSKILNIHKKTSDSENKPNDKLDKDGINKEMECGSSDDDLSSSLSVSKSALEEALMDRLQF
SIO_010081: YPL166W
subclass of: SO_0000673
so part of: YPL166W
location: 237338..237979
location: region:237338-237979:1
so has part: feature:237338-237979:1:exon

NP_015159.1
type: Protein
SIO_000068: ncbiprotein

S000006087
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237338-237979:1:exon

YPL165C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SET6
locus tag: YPL165C
so part of: sequence
location: complement(<237956..>239077)
location: region:237956-239077:-1
so has part: feature:237956-239077:-1:exon
subclass of: SO_0000010

855938
type: Gene
SIO_000068: ncbigene

position:237956:-1
position: 237956
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:239077:-1
position: 239077
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237956-239077:-1:exon

YPL165C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SET6
locus tag: YPL165C
product: Set6p
transcript id: NM_001183979.1
SIO_010081: YPL165C
subclass of: SO_0000673
so part of: YPL165C
location: complement(<237956..>239077)
location: region:237956-239077:-1
so has part: feature:237956-239077:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237956-239077:-1:exon

YPL165C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SET6
locus tag: YPL165C
note: SET domain hypothetical protein; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability
codon start: 1
product: Set6p
translation: MTIDGDVHEISPFFQVRQTKWGGRACFSNGNIPKGTTVLQVSNFTGTSISYEFRKEVCHNCFAYANAKTMKYKLNYDYLRDLVCNAHYQINPKKFLGAGLWFCSEHCRTSYLQIPNIIELIECYEILLHHFPSMLKRYNYTSEQEEKLNSILISENVIQSSWDEIESKWIPRINNMKSAKRINQLPPTCEDEYCCIRFVCESLFNLKYMDPQCITYRAFNMLQSNELSKISKFPVLLHFQKLVFQTLYILLPSHLHRMLSIPLLRHILGTEYGNAFGLWQEGEASDSREYFGYWVFPEASYFNHSCNPNITKYRKGNSMLFTMNRDIKKDEQICIDYSGVLDLPTVKRRAFLADSWFFDCACERCKSELQSVH
SIO_010081: YPL165C
subclass of: SO_0000673
so part of: YPL165C
location: complement(237956..239077)
location: region:237956-239077:-1
so has part: feature:237956-239077:-1:exon

NP_015160.1
type: Protein
SIO_000068: ncbiprotein

S000006086
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237956-239077:-1:exon

YPL164C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MLH3
locus tag: YPL164C
so part of: sequence
location: complement(<239350..>241497)
location: region:239350-241497:-1
so has part: feature:239350-241497:-1:exon
subclass of: SO_0000010

855939
type: Gene
SIO_000068: ncbigene

position:239350:-1
position: 239350
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:241497:-1
position: 241497
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:239350-241497:-1:exon

YPL164C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MLH3
locus tag: YPL164C
product: mismatch repair protein MLH3
transcript id: NM_001183978.1
SIO_010081: YPL164C
subclass of: SO_0000673
so part of: YPL164C
location: complement(<239350..>241497)
location: region:239350-241497:-1
so has part: feature:239350-241497:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:239350-241497:-1:exon

YPL164C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MLH3
locus tag: YPL164C
experiment: EXISTENCE:mutant phenotype:GO:0000710 meiotic mismatch repair [PMID:23316435]
experiment: EXISTENCE:mutant phenotype:GO:0006298 mismatch repair [PMID:10679328|PMID:9770499]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:10570173]
experiment: EXISTENCE:physical interaction:GO:0005634 nucleus [PMID:10570173]
experiment: EXISTENCE:physical interaction:GO:0097587 MutLgamma complex [PMID:9770499|PMID:10570173]
note: Protein involved in DNA mismatch repair and meiotic recombination; involved in crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability
codon start: 1
product: mismatch repair protein MLH3
translation: MSQHIRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFAVYDDGIGLTRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYNSAWMRKFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEPPFKTFNTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLRNVFGAIIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSLFQAQDFGEKGMSLLKTKSVGKPYRSHPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVKTIRSFLTFQGYLTPDKSDSSFEIVNCSQKTATLPDSRIQISKRNQVLNSKMKIARINSYIGKPAVNGCRINNSTINYEKIKNIRIDGQKSRLRNKLSSRPYDSGFTEDYDSIGKTITDFSISRSVLAKYEVINQVDKKFILIRCLDQSIHNCPLLVLVDQHACDERIRLEELFYSLLTEVVTGTFVARDLKDCCIEVDRTEADLFKHYQSEFKKWGIGYETIEGTMETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLPMDLSHFENYTSVDKLYWWKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILISKLSRCHNPFECAHGRPSMVPIAELK
SIO_010081: YPL164C
subclass of: SO_0000673
so part of: YPL164C
location: complement(239350..241497)
location: region:239350-241497:-1
so has part: feature:239350-241497:-1:exon

NP_015161.1
type: Protein
SIO_000068: ncbiprotein

S000006085
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:239350-241497:-1:exon

YPL163C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SVS1
locus tag: YPL163C
so part of: sequence
location: complement(<241918..>242700)
location: region:241918-242700:-1
so has part: feature:241918-242700:-1:exon
subclass of: SO_0000010

855940
type: Gene
SIO_000068: ncbigene

position:241918:-1
position: 241918
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:242700:-1
position: 242700
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:241918-242700:-1:exon

YPL163C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SVS1
locus tag: YPL163C
product: Svs1p
transcript id: NM_001183977.1
SIO_010081: YPL163C
subclass of: SO_0000673
so part of: YPL163C
location: complement(<241918..>242700)
location: region:241918-242700:-1
so has part: feature:241918-242700:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:241918-242700:-1:exon

YPL163C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SVS1
locus tag: YPL163C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:11935221]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Cell wall and vacuolar protein; required for wild-type resistance to vanadate; SVS1 has a paralog, SRL1, that arose from the whole genome duplication
codon start: 1
product: Svs1p
translation: MIFKILCSLLLVTSNFASALYVNETTSYTPYTKTLTPTYSVSPQETTLTYSDETTTFYITSTFYSTYWFTTSQSAAIISTPTASTPTASTPSLTTSTNEYTTTYSDTDTTYTSTLTSTYIITLSTESANEKAEQISTSVTEIASTVTESGSTYTSTLTSTLLVTVYNSQASNTIATSTAGDAASNVDALEKLVSAEHQSQMIQTTSADEQYCSASTKYVTVTAAAVTEVVTTTAEPVVKYVTITADASNVTGSANNGTHI
SIO_010081: YPL163C
subclass of: SO_0000673
so part of: YPL163C
location: complement(241918..242700)
location: region:241918-242700:-1
so has part: feature:241918-242700:-1:exon

NP_015162.1
type: Protein
SIO_000068: ncbiprotein

S000006084
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:241918-242700:-1:exon

YPL162C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL162C
so part of: sequence
location: complement(<243206..>244027)
location: region:243206-244027:-1
so has part: feature:243206-244027:-1:exon
subclass of: SO_0000010

855941
type: Gene
SIO_000068: ncbigene

position:243206:-1
position: 243206
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:244027:-1
position: 244027
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:243206-244027:-1:exon

YPL162C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL162C
product: uncharacterized protein
transcript id: NM_001183976.1
SIO_010081: YPL162C
subclass of: SO_0000673
so part of: YPL162C
location: complement(<243206..>244027)
location: region:243206-244027:-1
so has part: feature:243206-244027:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:243206-244027:-1:exon

YPL162C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL162C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology
codon start: 1
product: uncharacterized protein
translation: MYVSNGKDTCQLLGPVSLFVQTLMGMTAVIVLLVKRNYEHPRRKMIVWSYDIGKQIIGSLGIHFLNLGISILKKRRRSLFAITAKGNDDEDQCDWYFLNLLLDTTVGIPILWLCLYIIEKVLKSLHFQNIESGNYFPSKTVGSHPRKPLFSAFVKQLLIFIVGLGVMKFCVFLILNYLEDLAYWFADLILGWSDSWPNFQVFLVMFVFPILLNCFQYFCVDNVIRLHSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISSYGSII
SIO_010081: YPL162C
subclass of: SO_0000673
so part of: YPL162C
location: complement(243206..244027)
location: region:243206-244027:-1
so has part: feature:243206-244027:-1:exon

NP_015163.1
type: Protein
SIO_000068: ncbiprotein

S000006083
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:243206-244027:-1:exon

YPL161C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ROM7
gene: BEM4
locus tag: YPL161C
gene synonym: ROM7
so part of: sequence
location: complement(<244319..>246220)
location: region:244319-246220:-1
so has part: feature:244319-246220:-1:exon
subclass of: SO_0000010

855942
type: Gene
SIO_000068: ncbigene

position:244319:-1
position: 244319
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246220:-1
position: 246220
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:244319-246220:-1:exon

YPL161C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ROM7
gene: BEM4
locus tag: YPL161C
gene synonym: ROM7
product: Bem4p
transcript id: NM_001183975.1
SIO_010081: YPL161C
subclass of: SO_0000673
so part of: YPL161C
location: complement(<244319..>246220)
location: region:244319-246220:-1
so has part: feature:244319-246220:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:244319-246220:-1:exon

YPL161C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ROM7
gene: BEM4
locus tag: YPL161C
gene synonym: ROM7
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0007266 Rho protein signal transduction [PMID:8754839]
experiment: EXISTENCE:mutant phenotype:GO:0030010 establishment of cell polarity [PMID:8754839]
note: Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length
codon start: 1
product: Bem4p
translation: MDYEEILFGLQPILNASSIKDVPMNDVYLGSYLAVMDQLAVSLREPSNRDIVGKTGLLLNLVRVLEQALDICFHDTSISINDKIAFYEISSEVIRCIANAIIDNDDNREILLDSGGKKLLNYYIGGVLQLDEISSDKSEDSLVDKLQMRSVVLLRNFCIGNLKYTENLAPFIRGPLFVLLKTTQYSYLSSPEKVVLGSDLLNDILKVNYSNVQISDLFFLSQYIKKISSNVQNKELQAMEDGAVEAYSNTETQKFAGQGNQEYIEKEEEDDEEDVNCELLLNLSTCLETIVAKDETINFTNEEQLVLSMQKNLILSLVCLESKTFNNKLIVMRRLISCAGNISANLTNSNKREQSLCIETIKSSASSYALAAALMILCNSVASKSDAVALLKLISLSELIQVGSLLQDPLQYQGFLDLLRKLLNLENTMWLDIKDLFTLFQIMRRCHEQTKYYNNLRSLLTNLLNKTLTVLPSSKIHNSISSDPTIISFIAEHGTLTSCIAMDKLLVSKKALPKEAITSLWDSIFKFQNLGQAEQLSISDLFHITKTVGIYLKDSSVTADVNPIENILFKDYIQKLTLILETILSFKENKDKGSESCFNNGKFIAGIILNIVKNTKCLTPEEQNLEALAKSFF
SIO_010081: YPL161C
subclass of: SO_0000673
so part of: YPL161C
location: complement(244319..246220)
location: region:244319-246220:-1
so has part: feature:244319-246220:-1:exon

NP_015164.1
type: Protein
SIO_000068: ncbiprotein

S000006082
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:244319-246220:-1:exon

YPL160W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC60
locus tag: YPL160W
so part of: sequence
location: <246990..>250262
location: region:246990-250262:1
so has part: feature:246990-250262:1:exon
subclass of: SO_0000010

855943
type: Gene
SIO_000068: ncbigene

position:246990:1
position: 246990
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:250262:1
position: 250262
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246990-250262:1:exon

YPL160W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC60
locus tag: YPL160W
product: leucine--tRNA ligase CDC60
transcript id: NM_001183974.1
SIO_010081: YPL160W
subclass of: SO_0000673
so part of: YPL160W
location: <246990..>250262
location: region:246990-250262:1
so has part: feature:246990-250262:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:246990-250262:1:exon

YPL160W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC60
locus tag: YPL160W
EC number: 6.1.1.4
experiment: EXISTENCE:direct assay:GO:0004823 leucine-tRNA ligase activity [PMID:9742237]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9742237]
experiment: EXISTENCE:direct assay:GO:0006429 leucyl-tRNA aminoacylation [PMID:9742237]
experiment: EXISTENCE:mutant phenotype:GO:1903432 regulation of TORC1 signaling [PMID:22424774]
experiment: EXISTENCE:physical interaction:GO:1903432 regulation of TORC1 signaling [PMID:22424774]
note: Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA; human homolog LARS can complement yeast temperature-sensitive mutant at restrictive temperature
codon start: 1
product: leucine--tRNA ligase CDC60
translation: MSSGLVLENTARRDALIAIEKKYQKIWAEEHQFEIDAPSIEDEPITMDSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILACADKLKREAELFGKNFDNVPAEEEEIKEETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIMLQLGIPREEIIKFADAKYWLTYFPPLCESDCTSLGARIDWRRSFVTTDANPYYDAFIRWQMNKLKAAGKIKFGERYTIYSEKDGQACMDHDRQSGEGVTPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVSPTIEYGIFDAGDSYFITTERAFKNMSYQKLTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYPELRILPMETVIATKGTGVVTCVPSNSPDDYITTKDLLHKPEYYGIKPEWIDHEIVPIMHTEKYGDLTAKAIVEEKKIQSPKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAFVYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKNWAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFKDYYGNEIGPLGISADQMTDEVFDYIFQHQDDVKNTNIPLPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFPKKFWPKGIRANGHLMLNNSKMSKSTGNFMTLEQTVEKFGADAARIAFADAGDTVEDANFDESNANAAILRLFNLKEWAEEITKESNLRTGEITDFFDIAFEHEMNALIEKTYEQYALTNYKNALKYGLFDFQAARDYYREASGVMHKDLIARYIETQALLLAPIAPHFAEYIYREVLGNQTSVQNAKFPRASKPVDKGVLAALDYLRNLQRSIREGEGQALKKKKGKSAEIDASKPVKLTLLISESFPEWQSQCVEIVRKLFSEQTLDDNKKVREHIEPKEMKRAMPFISLLKQRLANEKPEDVFERELQFSEIDTVKAAARNVKKAAQALKIAEFSAISFPYGAKTGKDIFTGEEVEIPPVTKIVENAVPGNPGVVFQNI
SIO_010081: YPL160W
subclass of: SO_0000673
so part of: YPL160W
location: 246990..250262
location: region:246990-250262:1
so has part: feature:246990-250262:1:exon

NP_015165.1
type: Protein
SIO_000068: ncbiprotein

S000006081
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:246990-250262:1:exon

YPL159C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PET20
locus tag: YPL159C
so part of: sequence
location: complement(<250907..>251668)
location: region:250907-251668:-1
so has part: feature:250907-251668:-1:exon
subclass of: SO_0000010

855944
type: Gene
SIO_000068: ncbigene

position:250907:-1
position: 250907
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:251668:-1
position: 251668
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:250907-251668:-1:exon

YPL159C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PET20
locus tag: YPL159C
product: Pet20p
transcript id: NM_001183973.1
SIO_010081: YPL159C
subclass of: SO_0000673
so part of: YPL159C
location: complement(<250907..>251668)
location: region:250907-251668:-1
so has part: feature:250907-251668:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:250907-251668:-1:exon

YPL159C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PET20
locus tag: YPL159C
experiment: EXISTENCE:direct assay:GO:0000262 mitochondrial chromosome [PMID:31532710]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16491469]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:16491469]
note: Mitochondrial protein; required for respiratory growth under some conditions and for stability of the mitochondrial genome; subunit of a complex containing Mrx6p, Pim1p, and Mam33p that may regulate mtDNA replication
codon start: 1
product: Pet20p
translation: MLKLARPFIPPLSRNNAISSGIVLTSRRFQSSFTFLSNQSLLSKNQMKSKRKKGSKKAAYHRQPPEHEHTAPLIKQNKTITKKEHSDVRGSHLKKKRSDFSWLPRVPSTSHLKQSDMTTNVLYSGYRPLFINPNDPKLKEDTGSTLYEFAMKLEDLNEPLSPWISSATGLEFFSEWENIPSELLKNLKPFHPPKEKSMNTNELIHVSAKRNTLVDNKTSETLQRKMDEFSKRRGKGRKKSVVTLLQMKKKLEG
SIO_010081: YPL159C
subclass of: SO_0000673
so part of: YPL159C
location: complement(250907..251668)
location: region:250907-251668:-1
so has part: feature:250907-251668:-1:exon

NP_015166.1
type: Protein
SIO_000068: ncbiprotein

S000006080
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:250907-251668:-1:exon

YPL158C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GPS1
gene: AIM44
locus tag: YPL158C
gene synonym: GPS1
so part of: sequence
location: complement(<252034..>254310)
location: region:252034-254310:-1
so has part: feature:252034-254310:-1:exon
subclass of: SO_0000010

855945
type: Gene
SIO_000068: ncbigene

position:252034:-1
position: 252034
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:254310:-1
position: 254310
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:252034-254310:-1:exon

YPL158C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GPS1
gene: AIM44
locus tag: YPL158C
gene synonym: GPS1
product: Aim44p
transcript id: NM_001183972.1
SIO_010081: YPL158C
subclass of: SO_0000673
so part of: YPL158C
location: complement(<252034..>254310)
location: region:252034-254310:-1
so has part: feature:252034-254310:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:252034-254310:-1:exon

YPL158C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GPS1
gene: AIM44
locus tag: YPL158C
gene synonym: GPS1
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:28148650]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:23468594|PMID:28148650|PMID:14562095|PMID:22842922|P MID:24451263]
experiment: EXISTENCE:direct assay:GO:0032153 cell division site [PMID:25416945]
experiment: EXISTENCE:direct assay:GO:0032174 cellular bud neck septin collar [PMID:30341817]
experiment: EXISTENCE:direct assay:GO:0032177 cellular bud neck split septin rings [PMID:30341817]
experiment: EXISTENCE:genetic interaction:GO:1990344 secondary cell septum biogenesis [PMID:23468594]
experiment: EXISTENCE:mutant phenotype:GO:0005637 nuclear inner membrane [PMID:30341817]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:30341817]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:25416945]
experiment: EXISTENCE:mutant phenotype:GO:0045185 maintenance of protein location [PMID:23468594]
experiment: EXISTENCE:mutant phenotype:GO:0098841 protein localization to cell division site after cytokinesis [PMID:25416945]
experiment: EXISTENCE:mutant phenotype:GO:1901900 regulation of protein localization to cell division site [PMID:23468594]
experiment: EXISTENCE:mutant phenotype:GO:1903473 positive regulation of mitotic actomyosin contractile ring contraction [PMID:24451263]
experiment: EXISTENCE:mutant phenotype:GO:1990344 secondary cell septum biogenesis [PMID:23468594]
note: Regulator of Cdc42p and Rho1p; regulates AMR closure through Hof1p; inhibits Cdc42-dependent Cla4 activation at the division site, to prevent budding in the old bud neck; recruits Nis1p and Nba1p to the division site with Nap1 and the Rax1p-Rax2p dependent inheritance of Nis1p and Nba1p to bud scars to prevent division site repolarization; keeps Rho1p at the division site after AMR contraction to control secondary septum formation; relocalizes from bud neck to cytoplasm upon replication stress
codon start: 1
product: Aim44p
translation: MIIRAPIRTKTKSFRGDQMDFKFPSNESLPRGTLEEYHLNNHHLLNDVFAAENGVSRDEDGNSQTLSDYTSTSNTNTNSGYSSNGYYSFANISDNTTSSPRIVINQNETARLTSSDSNKSDFFASHDFPGNDSLHYSSSNVVKNQLHSMEAIPEGNITGSISTAFQTIPTADNVSYDIAPSSASSLLPRKSTSKSAILPSTQEAKPMTKLNMEKDIKTIELNNSVVPKPKKKLNRVPTIRRVESSRFSNSRYSSSVSSKSSSSRCSLKRSKAIRCKGGLLYYFTSLGIKIKKKLRKLRLVLRRRLFSYNVQKVPSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRQKKSQRYVSNLQRSISSKSLVPVLAPQKKTKPLTVDTKFKANHPQSEDSKVGSNTPRSPLVSYTPSLRRTNSSIRRAASILTASATMTPANNKNSFISVPDNVSHAVTRNSSMYSRSRLVRSKPSTALNAIARQPSIVVENKVIPLSMNRYSIKEEDEYVIDTSSMRELSPVNSVCSSDYDRESSESYSNYADAMETTEVDNKDRVECNNEIQNVDANNEETSNEESYNLMKHYLSTVIAQRIMLRVQIARIQNYKSNVVYMNKSAETNSTIYEDLVDSLLTEYEADGSSSQIFDGVTVRADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEEKRKEGEGRNLAKEVDELAELSPMRKQSDLSITLRSPFAMLNPAYSNSIISLPTGVVKRSLTLPVGMKI
SIO_010081: YPL158C
subclass of: SO_0000673
so part of: YPL158C
location: complement(252034..254310)
location: region:252034-254310:-1
so has part: feature:252034-254310:-1:exon

NP_015167.1
type: Protein
SIO_000068: ncbiprotein

S000006079
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:252034-254310:-1:exon

YPL157W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TGS1
locus tag: YPL157W
so part of: sequence
location: <254814..>255761
location: region:254814-255761:1
so has part: feature:254814-255761:1:exon
subclass of: SO_0000010

855946
type: Gene
SIO_000068: ncbigene

position:254814:1
position: 254814
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:255761:1
position: 255761
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:254814-255761:1:exon

YPL157W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TGS1
locus tag: YPL157W
product: RNA methyltransferase
transcript id: NM_001183971.1
SIO_010081: YPL157W
subclass of: SO_0000673
so part of: YPL157W
location: <254814..>255761
location: region:254814-255761:1
so has part: feature:254814-255761:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:254814-255761:1:exon

YPL157W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TGS1
locus tag: YPL157W
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11983179]
experiment: EXISTENCE:mutant phenotype:GO:0001510 RNA methylation [PMID:11983179]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:27348091]
experiment: EXISTENCE:mutant phenotype:GO:0008173 RNA methyltransferase activity [PMID:11983179]
experiment: EXISTENCE:mutant phenotype:GO:0017126 nucleologenesis [PMID:15340060]
experiment: EXISTENCE:mutant phenotype:GO:0032210 regulation of telomere maintenance via telomerase [PMID:18273059|PMID:18840651]
experiment: EXISTENCE:mutant phenotype:GO:0036261 7-methylguanosine cap hypermethylation [PMID:11983179]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:21398639]
note: Trimethyl guanosine synthase, conserved nucleolar methyl transferase; converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for nucleolar assembly and splicing of meiotic pre-mRNAs; interacts with Swm2p, which may confer substrate specificity on Tgs1p
codon start: 1
product: RNA methyltransferase
translation: MGRTFIHASKIKHAARKRKHHSNFRTLIKLLNNDAYKIESSKPLKNGKLFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDDRIWLKRGSWKKLVSKQKLSKIKYDCVFGSPPWGGPEYLRNDVYDLEQHLKPMGITKMLKSFLKLSPNVIMFLPRNSDLNQLSRATRKVLGPFAKCKVLYVKENGYMKGIFCMWGECFFNYEPASTENSRRESSEKEELSSENEELSKRKKHESTTTTKDNTVDIYDVNG
SIO_010081: YPL157W
subclass of: SO_0000673
so part of: YPL157W
location: 254814..255761
location: region:254814-255761:1
so has part: feature:254814-255761:1:exon

NP_015168.1
type: Protein
SIO_000068: ncbiprotein

S000006078
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:254814-255761:1:exon

YPL156C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM4
locus tag: YPL156C
so part of: sequence
location: complement(<255913..>256767)
location: region:255913-256767:-1
so has part: feature:255913-256767:-1:exon
subclass of: SO_0000010

855947
type: Gene
SIO_000068: ncbigene

position:255913:-1
position: 255913
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:256767:-1
position: 256767
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:255913-256767:-1:exon

YPL156C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM4
locus tag: YPL156C
product: pheromone-regulated protein PRM4
transcript id: NM_001183970.1
SIO_010081: YPL156C
subclass of: SO_0000673
so part of: YPL156C
location: complement(<255913..>256767)
location: region:255913-256767:-1
so has part: feature:255913-256767:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:255913-256767:-1:exon

YPL156C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM4
locus tag: YPL156C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift
codon start: 1
product: pheromone-regulated protein PRM4
translation: MIADSSVLKKHTAIKRSTRIISLTLVLLGVFSFLLLTWNDSLEFYNSADPSENKKNSEEESEKKFVYKLPNLLKTADSFLSNENELNFQKVKEEISNIQSEVEVDIPEPSSKATSKFSSRSFQTDNVVTATTTTTLNPRSSSLALQKNCDHKKFDPRTDFLDIIRTSPAVLFIKSSQADSIFLKNLLQREFEISPELATVDLEKHSHGYELEKYIKQNKLNIDTSAALESIQSPYLFLNGISVINRGMVRDIIEPHSKGLLLPLLKSEARGNLLVEKKDIPSNS
SIO_010081: YPL156C
subclass of: SO_0000673
so part of: YPL156C
location: complement(255913..256767)
location: region:255913-256767:-1
so has part: feature:255913-256767:-1:exon

NP_015169.1
type: Protein
SIO_000068: ncbiprotein

S000006077
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:255913-256767:-1:exon

YPL155C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KIP2
locus tag: YPL155C
so part of: sequence
location: complement(<257216..>259336)
location: region:257216-259336:-1
so has part: feature:257216-259336:-1:exon
subclass of: SO_0000010

855948
type: Gene
SIO_000068: ncbigene

position:257216:-1
position: 257216
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:259336:-1
position: 259336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:257216-259336:-1:exon

YPL155C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KIP2
locus tag: YPL155C
product: Kip2p
transcript id: NM_001183969.1
SIO_010081: YPL155C
subclass of: SO_0000673
so part of: YPL155C
location: complement(<257216..>259336)
location: region:257216-259336:-1
so has part: feature:257216-259336:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:257216-259336:-1:exon

YPL155C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KIP2
locus tag: YPL155C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:31490122]
experiment: EXISTENCE:direct assay:GO:0005881 cytoplasmic microtubule [PMID:9693366]
experiment: EXISTENCE:direct assay:GO:0007018 microtubule-based movement [PMID:31490122]
experiment: EXISTENCE:direct assay:GO:0007026 negative regulation of microtubule depolymerization [PMID:26576948]
experiment: EXISTENCE:direct assay:GO:0046785 microtubule polymerization [PMID:26576948]
experiment: EXISTENCE:direct assay:GO:1903754 cortical microtubule plus-end [PMID:15177030|PMID:18411245]
experiment: EXISTENCE:genetic interaction:GO:0008574 plus-end-directed microtubule motor activity [PMID:15177030|PMID:18411245]
experiment: EXISTENCE:mutant phenotype:GO:0007026 negative regulation of microtubule depolymerization [PMID:9693366]
experiment: EXISTENCE:mutant phenotype:GO:0008574 plus-end-directed microtubule motor activity [PMID:15177030]
experiment: EXISTENCE:mutant phenotype:GO:0030473 nuclear migration along microtubule [PMID:9693366]
note: Kinesin-related motor protein involved in mitotic spindle positioning; stabilizes microtubules by targeting Bik1p to the plus end; functions as a microtubule polymerase and catastrophe inhibitor in vitro; Kip2p levels are controlled during the cell cycle
codon start: 1
product: Kip2p
translation: MIQKMSPSLRRPSTRSSSGSSNIPQSPSVRSTSSFSNLTRNSIRSTSNSGSQSISASSTRSNSPLRSVSAKSDPFLHPGRIRIRRSDSINNNSRKNDTYTGSITVTIRPKPRSVGTSRDHVGLKSPRYSQPRSNSHHGSNTFVRDPWFITNDKTIVHEEIGEFKFDHVFASHCTNLEVYERTSKPMIDKLLMGFNATIFAYGMTGSGKTFTMSGNEQELGLIPLSVSYLFTNIMEQSMNGDKKFDVIISYLEIYNERIYDLLESGLEESGSRISTPSRLYMSKSNSNGLGVELKIRDDSQYGVKVIGLTERRCESSEELLRWIAVGDKSRKIGETDYNARSSRSHAIVLIRLTSTNVKNGTSRSSTLSLCDLAGSERATGQQERRKEGSFINKSLLALGTVISKLSADKMNSVGSNIPSPSASGSSSSSGNATNNGTSPSNHIPYRDSKLTRLLQPALSGDSIVTTICTVDTRNDAAAETMNTLRFASRAKNVALHVSKKSIISNGNNDGDKDRTIELLRRQLEEQRRMISELKNRSNIGEPLTKSSNESTYKDIKATGNDGDPNLALMRAENRVLKYKLENCEKLLDKDVVDLQDSEIMEIVEMLPFEVGTLLETKFQGLESQIRQYRKYTQKLEDKIMALEKSGHTAMSLTGCDGTEVIELQKMLERKDKMIEALQSAKRLRDRALKPLINTQQSPHPVVDNDK
SIO_010081: YPL155C
subclass of: SO_0000673
so part of: YPL155C
location: complement(257216..259336)
location: region:257216-259336:-1
so has part: feature:257216-259336:-1:exon

NP_015170.1
type: Protein
SIO_000068: ncbiprotein

S000006076
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:257216-259336:-1:exon

YPL154C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PHO9
alternative label: PRA1
alternative label: yscA
gene: PEP4
locus tag: YPL154C
gene synonym: PHO9; PRA1; yscA
so part of: sequence
location: complement(<259714..>260931)
location: region:259714-260931:-1
so has part: feature:259714-260931:-1:exon
subclass of: SO_0000010

855949
type: Gene
SIO_000068: ncbigene

position:259714:-1
position: 259714
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:260931:-1
position: 260931
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259714-260931:-1:exon

YPL154C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PHO9
alternative label: PRA1
alternative label: yscA
gene: PEP4
locus tag: YPL154C
gene synonym: PHO9; PRA1; yscA
product: proteinase A
transcript id: NM_001183968.1
SIO_010081: YPL154C
subclass of: SO_0000673
so part of: YPL154C
location: complement(<259714..>260931)
location: region:259714-260931:-1
so has part: feature:259714-260931:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:259714-260931:-1:exon

YPL154C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PHO9
alternative label: PRA1
alternative label: yscA
gene: PEP4
locus tag: YPL154C
gene synonym: PHO9; PRA1; yscA
EC number: 3.4.23.25
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:23708375|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008233 peptidase activity [PMID:7002931]
experiment: EXISTENCE:mutant phenotype:GO:0000425 pexophagy [PMID:31332264]
experiment: EXISTENCE:mutant phenotype:GO:0006624 vacuolar protein processing [PMID:26947009]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:23382696]
experiment: EXISTENCE:mutant phenotype:GO:0009267 cellular response to starvation [PMID:2674123]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:29514932]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:12529432]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0051603 proteolysis involved in protein catabolic process [PMID:16183335]
note: Vacuolar aspartyl protease (proteinase A); required for post-translational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; plays a protective role in acetic acid induced apoptosis; synthesized as a zymogen, self-activates; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway
codon start: 1
product: proteinase A
translation: MFSLKALLPLALLLVSANQVAAKVHKAKIYKHELSDEMKEVTFEQHLAHLGQKYLTQFEKANPEVVFSREHPFFTEGGHDVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGSCISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKAI
SIO_010081: YPL154C
subclass of: SO_0000673
so part of: YPL154C
location: complement(259714..260931)
location: region:259714-260931:-1
so has part: feature:259714-260931:-1:exon

NP_015171.1
type: Protein
SIO_000068: ncbiprotein

S000006075
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:259714-260931:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1612; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 260931..261727
location: region:260931-261727:1
so has part: feature:260931-261727:1:region

S000130198
type: SGD
SIO_000068: sgd

position:260931:1
position: 260931
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:261727:1
position: 261727
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:260931-261727:1:region

YPL153C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LSD1
alternative label: MEC2
alternative label: SPK1
gene: RAD53
locus tag: YPL153C
gene synonym: LSD1; MEC2; SPK1
so part of: sequence
location: complement(<261727..>264192)
location: region:261727-264192:-1
so has part: feature:261727-264192:-1:exon
subclass of: SO_0000010

855950
type: Gene
SIO_000068: ncbigene

position:261727:-1
position: 261727
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:264192:-1
position: 264192
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:261727-264192:-1:exon

YPL153C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LSD1
alternative label: MEC2
alternative label: SPK1
gene: RAD53
locus tag: YPL153C
gene synonym: LSD1; MEC2; SPK1
product: serine/threonine/tyrosine protein kinase RAD53
transcript id: NM_001183967.1
SIO_010081: YPL153C
subclass of: SO_0000673
so part of: YPL153C
location: complement(<261727..>264192)
location: region:261727-264192:-1
so has part: feature:261727-264192:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:261727-264192:-1:exon

YPL153C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LSD1
alternative label: MEC2
alternative label: SPK1
gene: RAD53
locus tag: YPL153C
gene synonym: LSD1; MEC2; SPK1
EC number: 2.7.12.1
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:16816422]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004712 protein serine/threonine/tyrosine kinase activity [PMID:8355715|PMID:30377154]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8355715|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:genetic interaction:GO:0000077 DNA damage checkpoint signaling [PMID:7926756]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:16816422]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:8355715]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:18045534]
experiment: EXISTENCE:mutant phenotype:GO:0009202 deoxyribonucleoside triphosphate biosynthetic process [PMID:17188244]
experiment: EXISTENCE:mutant phenotype:GO:0042326 negative regulation of phosphorylation [PMID:24130507]
experiment: EXISTENCE:mutant phenotype:GO:1901857 positive regulation of cellular respiration [PMID:31073026]
note: DNA damage response kinase; signal transduction pathway component required for DNA damage and replication checkpoints, promoting cell cycle arrest and DNA repair; role in initiation of DNA replication; inhibits gene gating through NPC protein phosphorylation, to promote fork stability; activates downstream kinase Dun1p; senses mtDNA depletion and mitochondrial ROS; relocalizes to cytosol under hypoxia; contains two FHA domains; human homolog CHEK2 implicated in breast cancer complements the null
codon start: 1
product: serine/threonine/tyrosine protein kinase RAD53
translation: MENITQPTQQSTQATQRFLIEKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIRSNLKNTSKIASPGLTSSTASSMVANKTGIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSPLGSQSYGDFSQISLSQSLSQQKLLENMDDAQYEFVKAQRKLQMEQQLQEQDQEDQDGKIQGFKIPAHAPIRYTQPKSIEAETREQKLLHSNNTENVKSSKKKGNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKLTQMMAAQRANQPSASSSSMSAKKPPVSDTNNNGNNSVLNDLVESPINANTGNILKRIHSVSLSQSQIDPSKKVKRAKLDQTSKGPENLQFS
SIO_010081: YPL153C
subclass of: SO_0000673
so part of: YPL153C
location: complement(261727..264192)
location: region:261727-264192:-1
so has part: feature:261727-264192:-1:exon

NP_015172.1
type: Protein
SIO_000068: ncbiprotein

S000006074
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:261727-264192:-1:exon

YPL152W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL152W-A
so part of: sequence
location: <264602..>264700
location: region:264602-264700:1
so has part: feature:264602-264700:1:exon
subclass of: SO_0000010

1466519
type: Gene
SIO_000068: ncbigene

position:264602:1
position: 264602
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:264700:1
position: 264700
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:264602-264700:1:exon

YPL152W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL152W-A
product: uncharacterized protein
transcript id: NM_001184627.1
SIO_010081: YPL152W-A
subclass of: SO_0000673
so part of: YPL152W-A
location: <264602..>264700
location: region:264602-264700:1
so has part: feature:264602-264700:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:264602-264700:1:exon

YPL152W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL152W-A
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MMVHLTLKSHLIKEELLWHALSPSYSCRYHGR
SIO_010081: YPL152W-A
subclass of: SO_0000673
so part of: YPL152W-A
location: 264602..264700
location: region:264602-264700:1
so has part: feature:264602-264700:1:exon

NP_878180.1
type: Protein
SIO_000068: ncbiprotein

S000028721
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:264602-264700:1:exon

YPL152W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YPA2
gene: RRD2
locus tag: YPL152W
gene synonym: YPA2
so part of: sequence
location: <265028..>266104
location: region:265028-266104:1
so has part: feature:265028-266104:1:exon
subclass of: SO_0000010

855951
type: Gene
SIO_000068: ncbigene

position:265028:1
position: 265028
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:266104:1
position: 266104
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265028-266104:1:exon

YPL152W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YPA2
gene: RRD2
locus tag: YPL152W
gene synonym: YPA2
product: peptidylprolyl isomerase RRD2
transcript id: NM_001183966.1
SIO_010081: YPL152W
subclass of: SO_0000673
so part of: YPL152W
location: <265028..>266104
location: region:265028-266104:1
so has part: feature:265028-266104:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:265028-266104:1:exon

YPL152W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YPA2
gene: RRD2
locus tag: YPL152W
gene synonym: YPA2
EC number: 5.2.1.8
experiment: EXISTENCE:direct assay:GO:0000159 protein phosphatase type 2A complex [PMID:17550305]
experiment: EXISTENCE:direct assay:GO:0003755 peptidyl-prolyl cis-trans isomerase activity [PMID:16380387]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:10660069]
experiment: EXISTENCE:mutant phenotype:GO:0007052 mitotic spindle organization [PMID:11262194]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:12952889]
note: Peptidyl-prolyl cis/trans-isomerase; also activates the phosphotyrosyl phosphatase activity of protein phosphatase 2A (PP2A); regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex; protein abundance increases in response to DNA replication stress
codon start: 1
product: peptidylprolyl isomerase RRD2
translation: MLPEKRLLTPDDMKLWEESPTRAHFTKFIIDLAESVKGHENSQYKEPISESINSMMNLLSQIKDITQKHPVIKDADSSRFGKVEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQLSIYLDESWGNKRRIDYGSGHELNFMCLLYGLYSYGIFNLSNDSTNLVLKVFIEYLKIMRILETKYWLEPAGSHGVWGLDDYHFLPFLFGAFQLTTHKHLKPISIHNNELVEMFAHRYLYFGCIAFINKVKSSASLRWHSPMLDDISGVKTWSKVAEGMIKMYKAEVLSKLPIMQHFYFSEFLPCPDGVSPPRGHIHDGTDKDDECNFEGHVHTTWGDCCGIKLPSAIAATEMNKKHHKPIPFD
SIO_010081: YPL152W
subclass of: SO_0000673
so part of: YPL152W
location: 265028..266104
location: region:265028-266104:1
so has part: feature:265028-266104:1:exon

NP_015173.1
type: Protein
SIO_000068: ncbiprotein

S000006073
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:265028-266104:1:exon

YPL151C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NTC50
gene: PRP46
locus tag: YPL151C
gene synonym: NTC50
so part of: sequence
location: complement(<266180..>267535)
location: region:266180-267535:-1
so has part: feature:266180-267535:-1:exon
subclass of: SO_0000010

855952
type: Gene
SIO_000068: ncbigene

position:266180:-1
position: 266180
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:267535:-1
position: 267535
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266180-267535:-1:exon

YPL151C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NTC50
gene: PRP46
locus tag: YPL151C
gene synonym: NTC50
product: mRNA splicing protein PRP46
transcript id: NM_001183965.1
SIO_010081: YPL151C
subclass of: SO_0000673
so part of: YPL151C
location: complement(<266180..>267535)
location: region:266180-267535:-1
so has part: feature:266180-267535:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:266180-267535:-1:exon

YPL151C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NTC50
gene: PRP46
locus tag: YPL151C
gene synonym: NTC50
experiment: EXISTENCE:direct assay:GO:0005681 spliceosomal complex [PMID:11884590]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:12554883]
experiment: EXISTENCE:physical interaction:GO:0000974 Prp19 complex [PMID:12088152]
note: Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs
codon start: 1
product: mRNA splicing protein PRP46
translation: MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTYRKESSSFSGEGKKVTLQHVPTDFSEASQAVISKKDHDTHASAFVNKIFQPEVAEELIVNRYEKLLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLSAKRF
SIO_010081: YPL151C
subclass of: SO_0000673
so part of: YPL151C
location: complement(266180..267535)
location: region:266180-267535:-1
so has part: feature:266180-267535:-1:exon

NP_015174.1
type: Protein
SIO_000068: ncbiprotein

S000006072
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:266180-267535:-1:exon

YPL150W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL150W
so part of: sequence
location: <268188..>270893
location: region:268188-270893:1
so has part: feature:268188-270893:1:exon
subclass of: SO_0000010

855953
type: Gene
SIO_000068: ncbigene

position:268188:1
position: 268188
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:270893:1
position: 270893
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:268188-270893:1:exon

YPL150W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL150W
product: non-specific serine/threonine protein kinase
transcript id: NM_001183964.1
SIO_010081: YPL150W
subclass of: SO_0000673
so part of: YPL150W
location: <268188..>270893
location: region:268188-270893:1
so has part: feature:268188-270893:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:268188-270893:1:exon

YPL150W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL150W
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0036464 cytoplasmic ribonucleoprotein granule [PMID:25342717]
note: Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study
codon start: 1
product: non-specific serine/threonine protein kinase
translation: MVNPVGSSKLEQNNIKSIIGSSYNRLYSQFTSDELTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKLERRLLKRLKQSGVDTQAIKQSILKKKCDSLSGLWLLLLAQGKKQENCKYPKRSRSVLSVKKVIESATHNDTNGISEDVLKPSLELSRAASLSKMLNKGSDFVTSMTPVSRKKSKDSAKVLNPTLSKISSQRAYSHSIAGSPRKSNNFLQKVSSFFKSKKSSNSNSNNSIHTNVSESLIASNRGAPSSGSFLKKNSGSIQKSRTDTVANPSRTESIGSLNENVAGAIVPRSANNTTLENKKTSGNEIGLKVAPELLLNEHIRIEEPRLKRFKSSISSEISQTSTGNYDSESAENSRSISFDGKVSPPPIRNRPLSEISQISNDTYISEYSTDGNNSSFKISDTIKPSYIRKGSETTSQYSASSEKMTNGYGRKFVRRDLSIVSTASSTSERSSRTDSFYDITTATPVVTTDNRRNKNNNLKESVLPRFGTQRPWTGKRTYTTSRHGKNARRSSKRGLFKITSSNTDSIIQEVSSSEEEDHNVIYSKGKGLPTPVLQTKGLIENGLNERDEEGDDEYAIHTDGEFSIKPQFSDDVIDKQNHLPSVKAVATKRSLSEGSNWSSSYLDSDNNRRRVSSLLVEDGGNPTA
SIO_010081: YPL150W
subclass of: SO_0000673
so part of: YPL150W
location: 268188..270893
location: region:268188-270893:1
so has part: feature:268188-270893:1:exon

NP_015175.1
type: Protein
SIO_000068: ncbiprotein

S000006071
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:268188-270893:1:exon

YPL149W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APG5
gene: ATG5
locus tag: YPL149W
gene synonym: APG5
so part of: sequence
location: <271310..>272194
location: region:271310-272194:1
so has part: feature:271310-272194:1:exon
subclass of: SO_0000010

855954
type: Gene
SIO_000068: ncbigene

position:271310:1
position: 271310
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272194:1
position: 272194
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:271310-272194:1:exon

YPL149W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APG5
gene: ATG5
locus tag: YPL149W
gene synonym: APG5
product: Atg5p
transcript id: NM_001183963.1
SIO_010081: YPL149W
subclass of: SO_0000673
so part of: YPL149W
location: <271310..>272194
location: region:271310-272194:1
so has part: feature:271310-272194:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:271310-272194:1:exon

YPL149W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APG5
gene: ATG5
locus tag: YPL149W
gene synonym: APG5
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:11689437|PMID:18497569]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005776 autophagosome [PMID:15155809]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11897782|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006501 C-terminal protein lipidation [PMID:17986448]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:23503366]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:23064152]
experiment: EXISTENCE:direct assay:GO:0019776 Atg8 ligase activity [PMID:17986448]
experiment: EXISTENCE:direct assay:GO:0034274 Atg12-Atg5-Atg16 complex [PMID:11897782]
experiment: EXISTENCE:direct assay:GO:0061908 phagophore [PMID:23549786]
experiment: EXISTENCE:direct assay:GO:0120095 vacuole-isolation membrane contact site [PMID:23549786]
experiment: EXISTENCE:direct assay:GO:0140355 cargo receptor ligand activity [PMID:27879200]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:8921905|PMID:32788210]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:10712513]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0044805 late nucleophagy [PMID:22768199]
experiment: EXISTENCE:mutant phenotype:GO:0061912 selective autophagy [PMID:27879200]
note: Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner
codon start: 1
product: Atg5p
translation: MNDIKQLLWNGELNVLVSIDPSFLMKGSPREIAVLRIRVPRETYLVNYMPLIWNKIKSFLSFDPLTDSEKYFWFEHNKTPIPWNYPVGVLFDCLAGKSATFTTSFENQVKDVLTFLRIHLVMGDSLPPTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFWGSVITRNFQDFIEISNKISSSRPRHIPLIIQTSRTSGTFRISQPTISMTGVNPTLKDIEGDILDVKEGINGNDVMVICQGIEIPWHMLLYDLYSKLRSFDGFLYITLVPIKGGDKASSEL
SIO_010081: YPL149W
subclass of: SO_0000673
so part of: YPL149W
location: 271310..272194
location: region:271310-272194:1
so has part: feature:271310-272194:1:exon

NP_015176.1
type: Protein
SIO_000068: ncbiprotein

S000006070
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:271310-272194:1:exon

YPL148C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PPT2
locus tag: YPL148C
so part of: sequence
location: complement(<272294..>272815)
location: region:272294-272815:-1
so has part: feature:272294-272815:-1:exon
subclass of: SO_0000010

855955
type: Gene
SIO_000068: ncbigene

position:272294:-1
position: 272294
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272815:-1
position: 272815
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:272294-272815:-1:exon

YPL148C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PPT2
locus tag: YPL148C
product: holo-[acyl-carrier-protein] synthase
transcript id: NM_001183962.1
SIO_010081: YPL148C
subclass of: SO_0000673
so part of: YPL148C
location: complement(<272294..>272815)
location: region:272294-272815:-1
so has part: feature:272294-272815:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:272294-272815:-1:exon

YPL148C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PPT2
locus tag: YPL148C
EC number: 2.7.8.7
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0008897 holo-[acyl-carrier-protein] synthase activity [PMID:9712852]
experiment: EXISTENCE:direct assay:GO:0031108 holo-[acyl-carrier-protein] biosynthetic process [PMID:9712852]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:9712852]
note: Phosphopantetheine:protein transferase (PPTase); activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation
codon start: 1
product: holo-[acyl-carrier-protein] synthase
translation: MSFASRNIGRKIAGVGVDIVYLPRFAHILEKYSPFDPCGRSTLNKITRKFMHEKERFHFSNLLIEENCLTPRLHEYIAGVWALKECSLKALCCCVSKHDLPPAQVLYAGMLYKTQTDTGVPQLEFDKMFGKKYPKYQQLSKNYDSLFSTHEFLVSLSHDKDYLIAVTNLVERE
SIO_010081: YPL148C
subclass of: SO_0000673
so part of: YPL148C
location: complement(272294..272815)
location: region:272294-272815:-1
so has part: feature:272294-272815:-1:exon

NP_015177.2
type: Protein
SIO_000068: ncbiprotein

S000006069
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:272294-272815:-1:exon

YPL147W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPI1
alternative label: PAL1
alternative label: PAT2
alternative label: SSH2
gene: PXA1
locus tag: YPL147W
gene synonym: LPI1; PAL1; PAT2; SSH2
so part of: sequence
location: <273255..>275867
location: region:273255-275867:1
so has part: feature:273255-275867:1:exon
subclass of: SO_0000010

855956
type: Gene
SIO_000068: ncbigene

position:273255:1
position: 273255
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:275867:1
position: 275867
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:273255-275867:1:exon

YPL147W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPI1
alternative label: PAL1
alternative label: PAT2
alternative label: SSH2
gene: PXA1
locus tag: YPL147W
gene synonym: LPI1; PAL1; PAT2; SSH2
product: ATP-binding cassette long-chain fatty acid transporter PXA1
transcript id: NM_001183961.1
SIO_010081: YPL147W
subclass of: SO_0000673
so part of: YPL147W
location: <273255..>275867
location: region:273255-275867:1
so has part: feature:273255-275867:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:273255-275867:1:exon

YPL147W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPI1
alternative label: PAL1
alternative label: PAT2
alternative label: SSH2
gene: PXA1
locus tag: YPL147W
gene synonym: LPI1; PAL1; PAT2; SSH2
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:22375831]
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:8670886|PMID:35127709]
experiment: EXISTENCE:direct assay:GO:0015867 ATP transport [PMID:35127709]
experiment: EXISTENCE:direct assay:GO:0042626 ATPase-coupled transmembrane transporter activity [PMID:35127709]
experiment: EXISTENCE:mutant phenotype:GO:0015908 fatty acid transport [PMID:8670886]
experiment: EXISTENCE:mutant phenotype:GO:0042626 ATPase-coupled transmembrane transporter activity [PMID:8670886]
note: Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transporters ABCD1and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant
codon start: 1
product: ATP-binding cassette long-chain fatty acid transporter PXA1
translation: MSTTLAAPAKLKSLLLNLHTHCIGLHVNDVTPKVYFKLLIRHLLQISRSNAAHPKLRRRAQILLVSLFLSGVTLFSGVTYSTFKIILKCYKFYKFPWKRRNRRPLIRRTRSQMQLDSGARIMYIPEVELVDRQSPDDNKFMNATDKKKRKRIFIPPKDNDVYEHDKFLFKNVELERAKNSQLFYSKFLNQMNVLSKILIPTVFDKNFLLLTAQIFFLVMRTWLSLFVAKLDGQIVKNIIAGRGRSFLWDLGCWFLIAVPASYTNSAIKLLQRKLSLNFRVNLTRYIHDMYLDKRLTFYKLIFDAKASNSVIKNIDNSITNDVAKFCDATCSVFANIAKPVIDLIFFSVYLRDNLGTVGVAGIFVNYFITGFILRKYTPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVDKVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTLATGINSEEKNMKEFIVNKRLMLSLADAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNLLPTTDNSQDAIRGTIQRNFNGIRLENIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSKSNSIQDLSKANDIKLPFLQGSGSSLLILGPNGCGKSSIQRIIAEIWPVYNKNGLLSIPSENNIFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDRGFRDKELVQILVEVKLDYLLKRGVGLTYLDAIADWKDLLSGGEKQRVNFARIMFHKPLYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGKWQLQAVGTDEAITSIDNEIEELERKLERVKGWEDERTKLREKLEII
SIO_010081: YPL147W
subclass of: SO_0000673
so part of: YPL147W
location: 273255..275867
location: region:273255-275867:1
so has part: feature:273255-275867:1:exon

NP_015178.1
type: Protein
SIO_000068: ncbiprotein

S000006068
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:273255-275867:1:exon

YPL146C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NOP53
locus tag: YPL146C
so part of: sequence
location: complement(<276162..>277529)
location: region:276162-277529:-1
so has part: feature:276162-277529:-1:exon
subclass of: SO_0000010

855957
type: Gene
SIO_000068: ncbigene

position:276162:-1
position: 276162
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:277529:-1
position: 277529
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:276162-277529:-1:exon

YPL146C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NOP53
locus tag: YPL146C
product: Nop53p
transcript id: NM_001183960.1
SIO_010081: YPL146C
subclass of: SO_0000673
so part of: YPL146C
location: complement(<276162..>277529)
location: region:276162-277529:-1
so has part: feature:276162-277529:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:276162-277529:-1:exon

YPL146C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NOP53
locus tag: YPL146C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16043506|PMID:10684247|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:16043506|PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0019843 rRNA binding [PMID:16128814]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:16043506]
experiment: EXISTENCE:mutant phenotype:GO:0000176 nuclear exosome (RNase complex) [PMID:31662437]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15686447]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:16128814]
note: Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p and with the nucleolar proteins Nop17p and Nip7p; null mutant is viable but growth is severely impaired
codon start: 1
product: Nop53p
translation: MAPTNLTKKPSQYKQSSRKGKKAWRKNIDLSDVEQYMEKKIDHEITHGTSDITSLQNDALFHVDVEGDEILKNKLIKRKQIKKVLKSKEILDAVKTNSKIAALNHHKNSSGNPNKIQGVSKHELKKLMALAGRVHGESKIKNRVAKDGLVKTTAGDLWGEESNSKKQKVKLPSGIKLDVEKKDQIPEELLKKSTTSWSTASVRPSTLDIEPIAVKEFTEIPHAGKSYNPNNKAWSELINKEYKEEKAREDERIALEKYKERIRHLMETLDDNEEEESSSNEEEEEEEEENENENESTQCSGSDKEIKLSINKPVKNKKKTKYQRNKAKRHEEKVKLQQELKELRQRVKDLEEVINSEETEILSAIESDSNKVKKSKKNKKHKLGTKYSVIDERLEIKFSDELSDSLRKLKPEGNLLYDTVRKLQSSGKVETRVPVRKGRKYKQKITEKWTHKDFK
SIO_010081: YPL146C
subclass of: SO_0000673
so part of: YPL146C
location: complement(276162..277529)
location: region:276162-277529:-1
so has part: feature:276162-277529:-1:exon

NP_015179.1
type: Protein
SIO_000068: ncbiprotein

S000006067
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:276162-277529:-1:exon

YPL145C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BSR3
alternative label: LPI3
alternative label: OSH4
gene: KES1
locus tag: YPL145C
gene synonym: BSR3; LPI3; OSH4
so part of: sequence
location: complement(<278395..>279699)
location: region:278395-279699:-1
so has part: feature:278395-279699:-1:exon
subclass of: SO_0000010

855958
type: Gene
SIO_000068: ncbigene

position:278395:-1
position: 278395
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:279699:-1
position: 279699
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:278395-279699:-1:exon

YPL145C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BSR3
alternative label: LPI3
alternative label: OSH4
gene: KES1
locus tag: YPL145C
gene synonym: BSR3; LPI3; OSH4
product: oxysterol-binding protein KES1
transcript id: NM_001183959.1
SIO_010081: YPL145C
subclass of: SO_0000673
so part of: YPL145C
location: complement(<278395..>279699)
location: region:278395-279699:-1
so has part: feature:278395-279699:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:278395-279699:-1:exon

YPL145C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BSR3
alternative label: LPI3
alternative label: OSH4
gene: KES1
locus tag: YPL145C
gene synonym: BSR3; LPI3; OSH4
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:11916983]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8978672|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:20008566]
experiment: EXISTENCE:direct assay:GO:0010922 positive regulation of phosphatase activity [PMID:21295699]
experiment: EXISTENCE:direct assay:GO:0015918 sterol transport [PMID:16585271|PMID:20008566]
experiment: EXISTENCE:direct assay:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:20729555]
experiment: EXISTENCE:direct assay:GO:0070300 phosphatidic acid binding [PMID:20729555]
experiment: EXISTENCE:direct assay:GO:0120015 sterol transfer activity [PMID:20008566]
experiment: EXISTENCE:genetic interaction:GO:0006887 exocytosis [PMID:17004323]
experiment: EXISTENCE:genetic interaction:GO:0006892 post-Golgi vesicle-mediated transport [PMID:11916983|PMID:8978672]
experiment: EXISTENCE:genetic interaction:GO:0006897 endocytosis [PMID:15173322]
experiment: EXISTENCE:genetic interaction:GO:0015918 sterol transport [PMID:16585271]
experiment: EXISTENCE:genetic interaction:GO:0030011 maintenance of cell polarity [PMID:17004323]
experiment: EXISTENCE:genetic interaction:GO:0034727 piecemeal microautophagy of the nucleus [PMID:15367582]
experiment: EXISTENCE:mutant phenotype:GO:0005546 phosphatidylinositol-4,5-bisphosphate binding [PMID:11916983]
experiment: EXISTENCE:mutant phenotype:GO:0006665 sphingolipid metabolic process [PMID:23593226]
experiment: EXISTENCE:mutant phenotype:GO:0008142 oxysterol binding [PMID:16136145]
experiment: EXISTENCE:mutant phenotype:GO:0008289 lipid binding [PMID:20008566]
experiment: EXISTENCE:mutant phenotype:GO:0015918 sterol transport [PMID:20008566]
experiment: EXISTENCE:mutant phenotype:GO:0035621 ER to Golgi ceramide transport [PMID:24213531]
experiment: EXISTENCE:mutant phenotype:GO:0120015 sterol transfer activity [PMID:20008566]
note: Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger; one of seven members of the yeast oxysterol binding protein family; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; KES1 has a paralog, HES1, that arose from the whole genome duplication
codon start: 1
product: oxysterol-binding protein KES1
translation: MSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVSHHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTPPPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKARIYKDSKDSKDKEKALYTISGQWSGSSKIIKANKKEESRLFYDAARIPAEHLNVKPLEEQHPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEEEAKGISWQRRWFKDFDYSVTPEEGALVPEKDDTFLKLASALNLSTKNAPSGTLVGDKEDRKEDLSSIHWRFQRELWDEEKEIVL
SIO_010081: YPL145C
subclass of: SO_0000673
so part of: YPL145C
location: complement(278395..279699)
location: region:278395-279699:-1
so has part: feature:278395-279699:-1:exon

NP_015180.1
type: Protein
SIO_000068: ncbiprotein

S000006066
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:278395-279699:-1:exon

YPL144W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DMP1
alternative label: PBA4
gene: POC4
locus tag: YPL144W
gene synonym: DMP1; PBA4
so part of: sequence
location: <280480..>280926
location: region:280480-280926:1
so has part: feature:280480-280926:1:exon
subclass of: SO_0000010

855959
type: Gene
SIO_000068: ncbigene

position:280480:1
position: 280480
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:280926:1
position: 280926
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:280480-280926:1:exon

YPL144W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DMP1
alternative label: PBA4
gene: POC4
locus tag: YPL144W
gene synonym: DMP1; PBA4
product: Poc4p
transcript id: NM_001183958.1
SIO_010081: YPL144W
subclass of: SO_0000673
so part of: YPL144W
location: <280480..>280926
location: region:280480-280926:1
so has part: feature:280480-280926:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:280480-280926:1:exon

YPL144W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DMP1
alternative label: PBA4
gene: POC4
locus tag: YPL144W
gene synonym: DMP1; PBA4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17707236]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:17707236]
experiment: EXISTENCE:genetic interaction:GO:0051131 chaperone-mediated protein complex assembly [PMID:17707236]
experiment: EXISTENCE:mutant phenotype:GO:0043248 proteasome assembly [PMID:18278055|PMID:18260085]
experiment: EXISTENCE:mutant phenotype:GO:0051131 chaperone-mediated protein complex assembly [PMID:17707236]
experiment: EXISTENCE:physical interaction:GO:0051131 chaperone-mediated protein complex assembly [PMID:18278055]
note: Component of a heterodimeric Poc4p-Irc25p chaperone; involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions; upregulates proteasome assembly in response to the unfolded protein response activated by mistargeting of proteins (UPRam)
codon start: 1
product: Poc4p
translation: MLVKTISRTIESESGFLQPTLDVIATLPADDRSKKIPISLVVGFKQEASLNSSSSLSCYYYAIPLMRDRHINLKSGGSNVVGIPLLDTKDDRIRDMARHMATIISERFNRPCYVTWSSLPSEDPSMLVANHLYILKKCLDLLKTELGE
SIO_010081: YPL144W
subclass of: SO_0000673
so part of: YPL144W
location: 280480..280926
location: region:280480-280926:1
so has part: feature:280480-280926:1:exon

NP_015181.1
type: Protein
SIO_000068: ncbiprotein

S000006065
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:280480-280926:1:exon

YNCP0005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR17B
locus tag: YNCP0005C
so part of: sequence
location: complement(281056..281517)
location: region:281056-281517:-1
so has part: feature:281056-281517:-1:exon
subclass of: SO_0000578

9164985
type: Gene
SIO_000068: ncbigene

position:281056:-1
position: 281056
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:281517:-1
position: 281517
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:281056-281517:-1:exon

YNCP0005C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR17B
locus tag: YNCP0005C
product: SNR17B
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:3327689]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:3327689|PMID:8455623]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:15231838|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0031428 box C/D RNP complex [PMID:10094313]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:12068309]
experiment: EXISTENCE:genetic interaction:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:7556076]
experiment: EXISTENCE:genetic interaction:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:7556076]
experiment: EXISTENCE:genetic interaction:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:7556076]
experiment: EXISTENCE:genetic interaction:GO:0003723 RNA binding [PMID:7556076]
experiment: EXISTENCE:genetic interaction:GO:0019843 rRNA binding [PMID:7556076]
experiment: EXISTENCE:mutant phenotype:GO:0019843 rRNA binding [PMID:7556076]
experiment: EXISTENCE:physical interaction:GO:0003723 RNA binding [PMID:3327689]
experiment: EXISTENCE:physical interaction:GO:0031428 box C/D RNP complex [PMID:10733567]
note: Small nucleolar RNA (snoRNA) U3; part of small (ribosomal) subunit (SSU) processosome; SNR17A also encodes snoRNA U3
transcript id: NR_132267.1
SIO_010081: YNCP0005C
subclass of: SO_0000673
so part of: YNCP0005C
location: complement(281056..281517)
location: region:281056-281517:-1
so has part: feature:281056-281517:-1:exon

S000007441
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:281056-281517:-1:exon

YPL143W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GCD17
alternative label: RPL37A
gene: RPL33A
locus tag: YPL143W
gene synonym: GCD17; RPL37A
so part of: sequence
location: <282122..>282970
location: region:282122-282970:1
so has part: feature:282122-282970:1:exon
subclass of: SO_0000010

855960
type: Gene
SIO_000068: ncbigene

position:282122:1
position: 282122
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:282970:1
position: 282970
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:282122-282970:1:exon

YPL143W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GCD17
alternative label: RPL37A
gene: RPL33A
locus tag: YPL143W
gene synonym: GCD17; RPL37A
product: ribosomal 60S subunit protein L33A
transcript id: NM_001183957.1
SIO_010081: YPL143W
subclass of: SO_0000673
so part of: YPL143W
location: join(<282122..282140,282666..>282970)
location: region:282122-282970:1
so has part: feature:282122-282140:1:exon
so has part: feature:282666-282970:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:282122-282140:1:exon

position:282140:1
position: 282140
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:282666-282970:1:exon

position:282666:1
position: 282666
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL143W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GCD17
alternative label: RPL37A
gene: RPL33A
locus tag: YPL143W
gene synonym: GCD17; RPL37A
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:17548477]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:17548477]
note: Ribosomal 60S subunit protein L33A; N-terminally acetylated; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33A has a paralog, RPL33B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L33A
translation: MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQDAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI
SIO_010081: YPL143W
subclass of: SO_0000673
so part of: YPL143W
location: join(282122..282140,282666..282970)
location: region:282122-282970:1
so has part: feature:282122-282140:1:exon
so has part: feature:282666-282970:1:exon

NP_015182.1
type: Protein
SIO_000068: ncbiprotein

S000006064
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:282122-282140:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:282666-282970:1:exon

YPL141C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FRK1
locus tag: YPL141C
so part of: sequence
location: complement(<283464..>286061)
location: region:283464-286061:-1
so has part: feature:283464-286061:-1:exon
subclass of: SO_0000010

855962
type: Gene
SIO_000068: ncbigene

position:283464:-1
position: 283464
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:286061:-1
position: 286061
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:283464-286061:-1:exon

YPL141C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FRK1
locus tag: YPL141C
product: protein kinase FRK1
transcript id: NM_001183955.1
SIO_010081: YPL141C
subclass of: SO_0000673
so part of: YPL141C
location: complement(<283464..>286061)
location: region:283464-286061:-1
so has part: feature:283464-286061:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:283464-286061:-1:exon

YPL141C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FRK1
locus tag: YPL141C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22289182|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
note: Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication
codon start: 1
product: protein kinase FRK1
translation: MSYTNKRHTYYGGFTNDLSDTFQYPQRTDEQRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPHSSFLSITPDEWDKLNNTQSVFRLAKPRRRYGSRPQSSCSTSSLGSRSDKRDSLVIDSTLITFPAPPQESQNHIITRPASIASDQRLSPIRRSNRHNRSNSAASVALQAVVNADREYVLSHEQSLSPVQNIRQTTGNMTASLSPPPAISPGDIIIETTPIKRNTISGSSIVPSLEEESSTTMQTSKIQPNNMASSQNHQYNKNKTQNSLQSAKNFYRTSSSSHTKPRPTSYHPGSYTTPPYNSNTLSIYEINEKAKSSASSQTLNQRDTSPFDSTPYLALDTCITSSSSIESSPKLITHGQFSVAKPSVDLQSVSGDLIKYKRDADVVTRIYDEKYKQKRKSLRYSGIFSDISCDTVTEESDELRPPESPLQQHEGQESIDKAKTEDTSEKGSKSSNIAKATAQKHVNNHLERSLNEAESTKKRFSFLSLYSYDTSKSSLYSSMDSKRKPSPPSQRRPKKDDSYQTNSKNHYITASNMQTSHQVSKDLPAPTMVQNKCTLETKKAVRSNRSSIMVSEVNKASVDNKAAQSPEHSTAKRVLGFFKRRSMKI
SIO_010081: YPL141C
subclass of: SO_0000673
so part of: YPL141C
location: complement(283464..286061)
location: region:283464-286061:-1
so has part: feature:283464-286061:-1:exon

NP_015184.1
type: Protein
SIO_000068: ncbiprotein

S000006062
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:283464-286061:-1:exon

YPL140C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPI6
alternative label: SSP33
gene: MKK2
locus tag: YPL140C
gene synonym: LPI6; SSP33
so part of: sequence
location: complement(<287514..>289034)
location: region:287514-289034:-1
so has part: feature:287514-289034:-1:exon
subclass of: SO_0000010

855963
type: Gene
SIO_000068: ncbigene

position:287514:-1
position: 287514
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:289034:-1
position: 289034
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:287514-289034:-1:exon

YPL140C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPI6
alternative label: SSP33
gene: MKK2
locus tag: YPL140C
gene synonym: LPI6; SSP33
product: putative mitogen-activated protein kinase kinase MKK2
transcript id: NM_001183954.1
SIO_010081: YPL140C
subclass of: SO_0000673
so part of: YPL140C
location: complement(<287514..>289034)
location: region:287514-289034:-1
so has part: feature:287514-289034:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:287514-289034:-1:exon

YPL140C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPI6
alternative label: SSP33
gene: MKK2
locus tag: YPL140C
gene synonym: LPI6; SSP33
EC number: 2.7.12.2
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12361575]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:12361575]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12361575]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:12361575]
experiment: EXISTENCE:genetic interaction:GO:0000196 cell wall integrity MAPK cascade [PMID:8386320]
experiment: EXISTENCE:genetic interaction:GO:0030242 autophagy of peroxisome [PMID:20385774]
experiment: EXISTENCE:genetic interaction:GO:0060237 regulation of fungal-type cell wall organization [PMID:8386320]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:8386320]
note: MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication
codon start: 1
product: putative mitogen-activated protein kinase kinase MKK2
translation: MASMFRPPESNRSHQKTPKLTLPVNLVQNAKSTNDGQHLNRSPYSSVNESPYSNNSTSATSTTSSMASNSTLLYNRSSTTTIKNRPVPPPLPPLVLTQKKDGIEYRVAGDSQLSERFSNLHVDITYKELLSSAPISTKLSNIDTTFIKKDLDTPEGEDSYPSTLLSAYDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQMKKKVNMERFVKKCWEKEKDGI
SIO_010081: YPL140C
subclass of: SO_0000673
so part of: YPL140C
location: complement(287514..289034)
location: region:287514-289034:-1
so has part: feature:287514-289034:-1:exon

NP_015185.1
type: Protein
SIO_000068: ncbiprotein

S000006061
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:287514-289034:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1614; Autonomously Replicating Sequence
so part of: sequence
location: 289485..289705
location: region:289485-289705:1
so has part: feature:289485-289705:1:region

S000118414
type: SGD
SIO_000068: sgd

position:289485:1
position: 289485
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:289705:1
position: 289705
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289485-289705:1:region

YPL139C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: WTM3
gene: UME1
locus tag: YPL139C
gene synonym: WTM3
so part of: sequence
location: complement(<289669..>291051)
location: region:289669-291051:-1
so has part: feature:289669-291051:-1:exon
subclass of: SO_0000010

855964
type: Gene
SIO_000068: ncbigene

position:289669:-1
position: 289669
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:291051:-1
position: 291051
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289669-291051:-1:exon

YPL139C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: WTM3
gene: UME1
locus tag: YPL139C
gene synonym: WTM3
product: Ume1p
transcript id: NM_001183953.1
SIO_010081: YPL139C
subclass of: SO_0000673
so part of: YPL139C
location: complement(<289669..>291051)
location: region:289669-291051:-1
so has part: feature:289669-291051:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:289669-291051:-1:exon

YPL139C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: WTM3
gene: UME1
locus tag: YPL139C
gene synonym: WTM3
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:9234739]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9234739|PMID:25398614]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:25398614]
experiment: EXISTENCE:direct assay:GO:0032221 Rpd3S/Clr6-CII complex [PMID:16286007|PMID:16286008]
experiment: EXISTENCE:direct assay:GO:0033698 Rpd3L complex [PMID:16286007|PMID:16286008|PMID:16314178|PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0016479 negative regulation of transcription by RNA polymerase I [PMID:19270272]
experiment: EXISTENCE:mutant phenotype:GO:0040020 regulation of meiotic nuclear division [PMID:9234739]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:17210643|PMID:20398213]
note: Component of both the Rpd3S and Rpd3L histone deacetylase complexes; negative regulator of meiosis; required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p; UME1 has a paralog, WTM2, that arose from the whole genome duplication
codon start: 1
product: Ume1p
translation: MSTLDIAEDNKIKNEEFKIWKKSIPSLYQHISSLKPIFGSGVDESPSTLRSIVFTNDSSCNKSKGVLSVPLLYSQGSEIFEVDCIVPLGLHYKKPESISEPLVQPDYTMESQKVEQTVLIPKWEFKGETIAKMIYVDNSEINVKVIALSTNGSLAWFREGVKSPVYTMMEPSTSLSSASSGNQNKPCVDFAISNDSKTLTVTKEKHLDNENATIKLIDNSGKIGEVLRTIPVPGIKNIQEIKFLNNQIFATCSDDGIIRFWGNEIGKKPLWILNDSLDGKTTCFAASPFVDTLFMTGTSGGALKVWDIRAVIALGDADAELNINQGHNKVNELFKVHHFYSEQVSKIEFSSISPMEVVTIGGLGNVYHWNFEPVFAIYNEIHEDFQGIISDELEAESMAFYHTEGCRREIGENNKVNTVAYHKYIEDLVATVDSDGLLTVYKPFTGKVLDGSREVGAAKS
SIO_010081: YPL139C
subclass of: SO_0000673
so part of: YPL139C
location: complement(289669..291051)
location: region:289669-291051:-1
so has part: feature:289669-291051:-1:exon

NP_015186.1
type: Protein
SIO_000068: ncbiprotein

S000006060
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:289669-291051:-1:exon

YPL138C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CPS40
alternative label: SAF41
gene: SPP1
locus tag: YPL138C
gene synonym: CPS40; SAF41
so part of: sequence
location: complement(<291366..>292427)
location: region:291366-292427:-1
so has part: feature:291366-292427:-1:exon
subclass of: SO_0000010

855965
type: Gene
SIO_000068: ncbigene

position:291366:-1
position: 291366
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:292427:-1
position: 292427
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:291366-292427:-1:exon

YPL138C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CPS40
alternative label: SAF41
gene: SPP1
locus tag: YPL138C
gene synonym: CPS40; SAF41
product: Spp1p
transcript id: NM_001183952.1
SIO_010081: YPL138C
subclass of: SO_0000673
so part of: YPL138C
location: complement(<291366..>292427)
location: region:291366-292427:-1
so has part: feature:291366-292427:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:291366-292427:-1:exon

YPL138C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CPS40
alternative label: SAF41
gene: SPP1
locus tag: YPL138C
gene synonym: CPS40; SAF41
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:18845545]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0035064 methylated histone binding [PMID:17142463]
experiment: EXISTENCE:direct assay:GO:0042800 histone H3K4 methyltransferase activity [PMID:11742990|PMID:11805083]
experiment: EXISTENCE:direct assay:GO:0051568 histone H3-K4 methylation [PMID:11742990|PMID:11752412|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0003682 chromatin binding [PMID:23246437]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:11687631]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:11687631|PMID:11752412|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0042800 histone H3K4 methyltransferase activity [PMID:11752412]
experiment: EXISTENCE:mutant phenotype:GO:0051568 histone H3-K4 methylation [PMID:11752412]
experiment: EXISTENCE:mutant phenotype:GO:1903341 regulation of meiotic DNA double-strand break formation [PMID:23246437]
experiment: EXISTENCE:physical interaction:GO:0048188 Set1C/COMPASS complex [PMID:11687631|PMID:11742990|PMID:11752412]
note: Subunit of COMPASS (Set1C); a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; promotes meiotic DSB formation by interacting with H3K4me3 and Rec107p, a protein required for Spo11p-catalyzed DSB formation located on chromosome axes; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein; relocalizes to cytosol in response to hypoxia
codon start: 1
product: Spp1p
translation: MSLPQWCPPHSTLKRNPTTGEDVYCICKRPDYGELMVGCDGCDDWFHFTCLHIPEQFKDLVFSFYCPYCQAGITGKNKDAIINGEGSLPKTLWKRKCRISDCYKPCLQDSKYCSEEHGREFVNDIWSRLKTDEDRAVVKKMVEQTGHIDKFKKFGQLDFIDNNIVVKTDDEKEIFDQIVVRDMTLKTLEDDLQEVQEISLPLFKKKLELLEVYLGWLDNVYTEMRKLDDDAASHVECGKEDSKGTKRKKKKNSSRSRARKNICGYCSTYERIPCSVEEFVRDFGSNEEATKIHEVCTKWKCNRHLDWVSTNQEQYLQQIDSLESMQERLQHLIQARKKQLNIQYYEEILRRGL
SIO_010081: YPL138C
subclass of: SO_0000673
so part of: YPL138C
location: complement(291366..292427)
location: region:291366-292427:-1
so has part: feature:291366-292427:-1:exon

NP_015187.1
type: Protein
SIO_000068: ncbiprotein

S000006059
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:291366-292427:-1:exon

YPL137C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GIP3
locus tag: YPL137C
so part of: sequence
location: complement(<292817..>296647)
location: region:292817-296647:-1
so has part: feature:292817-296647:-1:exon
subclass of: SO_0000010

855967
type: Gene
SIO_000068: ncbigene

position:292817:-1
position: 292817
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:296647:-1
position: 296647
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:292817-296647:-1:exon

YPL137C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GIP3
locus tag: YPL137C
product: protein phosphatase regulator GIP3
transcript id: NM_001183951.1
SIO_010081: YPL137C
subclass of: SO_0000673
so part of: YPL137C
location: complement(<292817..>296647)
location: region:292817-296647:-1
so has part: feature:292817-296647:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:292817-296647:-1:exon

YPL137C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GIP3
locus tag: YPL137C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008157 protein phosphatase 1 binding [PMID:11841235]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:16537909]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:16537909]
experiment: EXISTENCE:mutant phenotype:GO:0043666 regulation of phosphoprotein phosphatase activity [PMID:16537909]
note: Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments; GIP3 has a paralog, HER1, that arose from the whole genome duplication
codon start: 1
product: protein phosphatase regulator GIP3
translation: MITNTEFDVPVDWLYKGKSRRKTNTKPSRPSTSPASSSSTSSSKNGDNSTSGNRSSNDKPRARSSSVSNAALCNTEKPDLKRNDGNTSASDTDNIPLLTPINSGNRSDSADIDNPATVDAIDLIDNDDNGSSTQFVRKKRSTSISNAVVSSKPRLASSAINATASSSVGKGKHPPISSPSNATLKRSNSTSGEKTKRSIFGSLFSKRSTSSSASTAKKPLPVVNTSTTENESGGIKAVATPDPRVKEISSPMRGVAPTASKPQTPILPSPALAVKDLSTVSLKRVSFAVDKFESDPPQQLPSRTPKKGNILIPDDMISEVPSISVGISSSNQSAKSTNSNIKGPLYTKKSKEYILALENQKLALREAAKHQQEAHFAANRIAFEVANFKTASDAGGKLTEKSSEGTITKQREEVSPPNVEADRELENNKLAENLSKAGIDKPIHMHEHYFKEPDQDKYQDGHSIENNEVTLDVIYTRCCHLREILPIPSTLRQVKDKTAPLQILKFLNPKPTLIDILSFCDFITIAPIHTIVFDNVALNQDMFRIIISALVNSTVLDKLSLRNVRIDQDGWKLLCKFLLLNKSLNKLDISQTKIKSDLAESLYRHNMDWNLFTDVLSQRSHKPIEELLFNGIQFSKIPYSCFARLLTSFATQKNFPESGIRLGLAGATTSNISQDCLKFIFNWMSQYNVQGVDLAFNDLSTMIKPMVGKLSALSYDNLRYFILNSTNISTSYDLALLLKYLSKLPNLIFLDLSNLSQCFPDILPYMYKYLPRFPNLKRIHLDSNNLTLKELAVVCNILIKCKSLSHVSMTNQNVENFYLMNGTDSPVQQTNTDGDLDSSSTLDVKGQFAKNSFSSTLYAFARDSPNLIGLDFDYDLISEEIQSRIALCLMRNMKRTMDSTFQLDELDSQDDLLFDGSLVTMTAESVLEKLNLLSDKSTKVKKDTTKRYLLKKYIEKFHILHHNVQHTIDTMFEKRKSGELPLQEKENLVRLLLLEQNLCNILELFSHNPNLNDVLGSSRDDSKESVDSSEDSKLPALKHVESGYHVPEEKIQPENDVITARPHLMATDSGKTIDVFTGKPLVFKHTSSSTSVGCKKQEEEEGELHKWGFFVQQQRSLYPENESTRQTPFASGDTPINTETAGKSTSSPSVSTSNNETATTSLFSPANPKILPKIPSGAVLRSAIMKAKGIDSIDDLIQNVNSNNIELENIYGESIQNSASTFTPGVDSDVSAPNTDKGSVETLPAVSTDDPNCEVKVTATYDKLLNNLSMERSIRL
SIO_010081: YPL137C
subclass of: SO_0000673
so part of: YPL137C
location: complement(292817..296647)
location: region:292817-296647:-1
so has part: feature:292817-296647:-1:exon

NP_015188.1
type: Protein
SIO_000068: ncbiprotein

S000006058
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:292817-296647:-1:exon

YPL135W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NUA1
gene: ISU1
locus tag: YPL135W
gene synonym: NUA1
so part of: sequence
location: <297553..>298050
location: region:297553-298050:1
so has part: feature:297553-298050:1:exon
subclass of: SO_0000010

855968
type: Gene
SIO_000068: ncbigene

position:297553:1
position: 297553
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:298050:1
position: 298050
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:297553-298050:1:exon

YPL135W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NUA1
gene: ISU1
locus tag: YPL135W
gene synonym: NUA1
product: iron-binding protein ISU1
transcript id: NM_001183949.1
SIO_010081: YPL135W
subclass of: SO_0000673
so part of: YPL135W
location: <297553..>298050
location: region:297553-298050:1
so has part: feature:297553-298050:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:297553-298050:1:exon

YPL135W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NUA1
gene: ISU1
locus tag: YPL135W
gene synonym: NUA1
experiment: EXISTENCE:direct assay:GO:0001671 ATPase activator activity [PMID:12756240]
experiment: EXISTENCE:direct assay:GO:0005506 iron ion binding [PMID:31532427]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:10468587|PMID:15143178]
experiment: EXISTENCE:direct assay:GO:0008198 ferrous iron binding [PMID:12970193]
experiment: EXISTENCE:direct assay:GO:0008270 zinc ion binding [PMID:31532427]
experiment: EXISTENCE:genetic interaction:GO:0002098 tRNA wobble uridine modification [PMID:17283054]
experiment: EXISTENCE:genetic interaction:GO:0016226 iron-sulfur cluster assembly [PMID:12970193]
experiment: EXISTENCE:mutant phenotype:GO:0006879 cellular iron ion homeostasis [PMID:10468587]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:10588895|PMID:15143178|PMID:31040179]
note: Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant
codon start: 1
product: iron-binding protein ISU1
translation: MLPVITRFARPALMAIRPVNAMGVLRASSITKRLYHPKVIEHYTHPRNVGSLDKKLPNVGTGLVGAPACGDVMRLQIKVNDSTGVIEDVKFKTFGCGSAIASSSYMTELVQGMTLDDAAKIKNTEIAKELSLPPVKLHCSMLAEDAIKAAIKDYKSKRNTPTMLS
SIO_010081: YPL135W
subclass of: SO_0000673
so part of: YPL135W
location: 297553..298050
location: region:297553-298050:1
so has part: feature:297553-298050:1:exon

NP_015190.1
type: Protein
SIO_000068: ncbiprotein

S000006056
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:297553-298050:1:exon

YPL134C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ODC1
locus tag: YPL134C
so part of: sequence
location: complement(<298571..>299503)
location: region:298571-299503:-1
so has part: feature:298571-299503:-1:exon
subclass of: SO_0000010

855969
type: Gene
SIO_000068: ncbigene

position:298571:-1
position: 298571
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:299503:-1
position: 299503
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:298571-299503:-1:exon

YPL134C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ODC1
locus tag: YPL134C
product: mitochondrial 2-oxodicarboxylate carrier
transcript id: NM_001183948.1
SIO_010081: YPL134C
subclass of: SO_0000673
so part of: YPL134C
location: complement(<298571..>299503)
location: region:298571-299503:-1
so has part: feature:298571-299503:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:298571-299503:-1:exon

YPL134C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ODC1
locus tag: YPL134C
experiment: EXISTENCE:direct assay:GO:0005310 dicarboxylic acid transmembrane transporter activity [PMID:11013234]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:9178508|PMID:14576278|PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:11013234]
experiment: EXISTENCE:direct assay:GO:0006839 mitochondrial transport [PMID:11013234]
note: Mitochondrial inner membrane transporter; 2-oxodicarboxylate transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for lysine and glutamate biosynthesis and lysine catabolism; suppresses, in multicopy, an fmc1 null mutation; ODC1 has a paralog, ODC2, that arose from the whole genome duplication
codon start: 1
product: mitochondrial 2-oxodicarboxylate carrier
translation: MTSIDNRPLPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGAVEAFVVAPFELVKIRLQDVNSQFKTPIEVVKNSVVKGGVLSLFNGLEATIWRHVLWNAGYFGIIFQIRKLLPAAKTSTEKTRNDLIAGAIGGTVGCLLNTPFDVVKSRIQRSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLAPGGGLLLVVFTNVMDFFREVKYGKKQ
SIO_010081: YPL134C
subclass of: SO_0000673
so part of: YPL134C
location: complement(298571..299503)
location: region:298571-299503:-1
so has part: feature:298571-299503:-1:exon

NP_015191.1
type: Protein
SIO_000068: ncbiprotein

S000006055
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:298571-299503:-1:exon

YPL133C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RDS2
locus tag: YPL133C
so part of: sequence
location: complement(<299888..>301228)
location: region:299888-301228:-1
so has part: feature:299888-301228:-1:exon
subclass of: SO_0000010

855970
type: Gene
SIO_000068: ncbigene

position:299888:-1
position: 299888
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:301228:-1
position: 301228
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:299888-301228:-1:exon

YPL133C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RDS2
locus tag: YPL133C
product: gluconeogenesis transcription factor RDS2
transcript id: NM_001183947.1
SIO_010081: YPL133C
subclass of: SO_0000673
so part of: YPL133C
location: complement(<299888..>301228)
location: region:299888-301228:-1
so has part: feature:299888-301228:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:299888-301228:-1:exon

YPL133C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RDS2
locus tag: YPL133C
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:17875938]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:17875938]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11943786|PMID:17875938]
experiment: EXISTENCE:mutant phenotype:GO:0061414 positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source [PMID:17875938]
experiment: EXISTENCE:mutant phenotype:GO:0061415 negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source [PMID:17875938]
experiment: EXISTENCE:mutant phenotype:GO:0071466 cellular response to xenobiotic stimulus [PMID:11943786]
note: Transcription factor involved in regulating gluconeogenesis; also involved in the regulation of glyoxylate cycle genes; member of the zinc cluster family of proteins; confers resistance to ketoconazole
codon start: 1
product: gluconeogenesis transcription factor RDS2
translation: MSANSGVKRASKAFKTCLFCKRSHVVCDKQRPCSRCVKRDIAHLCREDDIAVPNEMPSQHESSPNDNNIQGKYANKAHTGIPSDYQNEPVNKSGSTYGEELSPKLDSSLVNDTTSLLLPQQPVFVSENVGSEFSSLNEFLSMLENPLLTQTSLSSSSASNVHLENGSQTTQSPLEYQNDNRRDEIGVARQENRSPTIMSGSSNSISKGDKQDQEKEESRILANANENSAPTPKEQFFLTAADPSTEMTPEHRLKLVINAKLEAGLLKPYNYAKGYARLQDYMDKYMNQSSKQRILKPLSTIRPAFRTIARSLKDVDLVLVEESFERMLLSYDRVFTSMSMPACLCRRTGEIYRANKEFASLVDCTVDDLRDGKLAIYELMTEESAVNFWEKYGSIAFDKGQKAVLTSCSLRTKDGIRKRPCCFSFTIRRDRYNIPICIVGNFIPLS
SIO_010081: YPL133C
subclass of: SO_0000673
so part of: YPL133C
location: complement(299888..301228)
location: region:299888-301228:-1
so has part: feature:299888-301228:-1:exon

NP_015192.1
type: Protein
SIO_000068: ncbiprotein

S000006054
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:299888-301228:-1:exon

YPL132W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPI13
alternative label: PSO7
gene: COX11
locus tag: YPL132W
gene synonym: LPI13; PSO7
so part of: sequence
location: <301716..>302618
location: region:301716-302618:1
so has part: feature:301716-302618:1:exon
subclass of: SO_0000010

855971
type: Gene
SIO_000068: ncbigene

position:301716:1
position: 301716
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:302618:1
position: 302618
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:301716-302618:1:exon

YPL132W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPI13
alternative label: PSO7
gene: COX11
locus tag: YPL132W
gene synonym: LPI13; PSO7
product: Cox11p
transcript id: NM_001183946.1
SIO_010081: YPL132W
subclass of: SO_0000673
so part of: YPL132W
location: <301716..>302618
location: region:301716-302618:1
so has part: feature:301716-302618:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:301716-302618:1:exon

YPL132W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPI13
alternative label: PSO7
gene: COX11
locus tag: YPL132W
gene synonym: LPI13; PSO7
experiment: EXISTENCE:direct assay:GO:0005507 copper ion binding [PMID:12063264]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005740 mitochondrial envelope [PMID:2167832]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:10501934|PMID:15776235]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0005761 mitochondrial ribosome [PMID:15776235]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:10617659]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:2167832]
note: Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; involved in oxidative stress response; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p
codon start: 1
product: Cox11p
translation: MIRICPIVRSKVPLLGTFLRSDSWLAPHALALRRAICKNVALRSYSVNSEQPKHTFDISKLTRNEIQQLRELKRARERKFKDRTVAFYFSSVAVLFLGLAYAAVPLYRAICARTGFGGIPITDRRKFTDDKLIPVDTEKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNYSDKDIIGMATYSIAPGEAAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPAMRNIDDIILHYTFFRAHYGDGTAVSDSKKEPEMNADEKAASLANAAILSPEVIDTRKDNSN
SIO_010081: YPL132W
subclass of: SO_0000673
so part of: YPL132W
location: 301716..302618
location: region:301716-302618:1
so has part: feature:301716-302618:1:exon

NP_015193.1
type: Protein
SIO_000068: ncbiprotein

S000006053
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:301716-302618:1:exon

YPL131W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPI14
alternative label: RPL1
gene: RPL5
locus tag: YPL131W
gene synonym: LPI14; RPL1
so part of: sequence
location: <303121..>304014
location: region:303121-304014:1
so has part: feature:303121-304014:1:exon
subclass of: SO_0000010

855972
type: Gene
SIO_000068: ncbigene

position:303121:1
position: 303121
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:304014:1
position: 304014
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:303121-304014:1:exon

YPL131W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPI14
alternative label: RPL1
gene: RPL5
locus tag: YPL131W
gene synonym: LPI14; RPL1
product: ribosomal 60S subunit protein L5
transcript id: NM_001183945.1
SIO_010081: YPL131W
subclass of: SO_0000673
so part of: YPL131W
location: <303121..>304014
location: region:303121-304014:1
so has part: feature:303121-304014:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:303121-304014:1:exon

YPL131W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPI14
alternative label: RPL1
gene: RPL5
locus tag: YPL131W
gene synonym: LPI14; RPL1
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0008097 5S rRNA binding [PMID:8764831]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:8474444]
note: Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly
codon start: 1
product: ribosomal 60S subunit protein L5
translation: MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
SIO_010081: YPL131W
subclass of: SO_0000673
so part of: YPL131W
location: 303121..304014
location: region:303121-304014:1
so has part: feature:303121-304014:1:exon

NP_015194.1
type: Protein
SIO_000068: ncbiprotein

S000006052
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:303121-304014:1:exon

YPL130W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPO19
locus tag: YPL130W
so part of: sequence
location: <304387..>305058
location: region:304387-305058:1
so has part: feature:304387-305058:1:exon
subclass of: SO_0000010

855973
type: Gene
SIO_000068: ncbigene

position:304387:1
position: 304387
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:305058:1
position: 305058
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:304387-305058:1:exon

YPL130W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPO19
locus tag: YPL130W
product: Spo19p
transcript id: NM_001183944.1
SIO_010081: YPL130W
subclass of: SO_0000673
so part of: YPL130W
location: <304387..>305058
location: region:304387-305058:1
so has part: feature:304387-305058:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:304387-305058:1:exon

YPL130W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPO19
locus tag: YPL130W
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:18756268]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953]
experiment: EXISTENCE:genetic interaction:GO:0051321 meiotic cell cycle [PMID:17179081]
experiment: EXISTENCE:genetic interaction:GO:0070583 spore membrane bending pathway [PMID:18756268]
experiment: EXISTENCE:mutant phenotype:GO:0070583 spore membrane bending pathway [PMID:18756268]
note: Meiosis-specific prospore protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; identified as a weak high-copy suppressor of the spo1-1 ts mutation; SPO19 has a paralog, YOR214C, that arose from the whole genome duplication
codon start: 1
product: Spo19p
translation: MKKQILIVAAQSILCSTVFGERSNVGLSTEELGGDSILYFNEDPIVIEIDKKAIDKKTLEQLASTRDVVLTDLPDTLEFIDFNEYAKMKSKSDMLLEYINEYEFDDFERSSEGGLEEEEEEDLIYDFNAQAEDLGKLGSNIYEVVEEKNIVNTYDGNLINASTTESTTTIRPFVTSHSYVASSTPYSNISSLNEDYDNASNFLTPTTVALAVLLTILLFIQAY
SIO_010081: YPL130W
subclass of: SO_0000673
so part of: YPL130W
location: 304387..305058
location: region:304387-305058:1
so has part: feature:304387-305058:1:exon

NP_015195.1
type: Protein
SIO_000068: ncbiprotein

S000006051
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:304387-305058:1:exon

YPL129W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ANC1
alternative label: SWP29
alternative label: TAF30
alternative label: TFG3
gene: TAF14
locus tag: YPL129W
gene synonym: ANC1; SWP29; TAF30; TFG3
so part of: sequence
location: <305298..>306137
location: region:305298-306137:1
so has part: feature:305298-306137:1:exon
subclass of: SO_0000010

855974
type: Gene
SIO_000068: ncbigene

position:305298:1
position: 305298
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:306137:1
position: 306137
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:305298-306137:1:exon

YPL129W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ANC1
alternative label: SWP29
alternative label: TAF30
alternative label: TFG3
gene: TAF14
locus tag: YPL129W
gene synonym: ANC1; SWP29; TAF30; TFG3
product: TATA-binding protein-associated factor TAF14
transcript id: NM_001183943.1
SIO_010081: YPL129W
subclass of: SO_0000673
so part of: YPL129W
location: join(<305298..305306,305412..>306137)
location: region:305298-306137:1
so has part: feature:305298-305306:1:exon
so has part: feature:305412-306137:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:305298-305306:1:exon

position:305306:1
position: 305306
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:305412-306137:1:exon

position:305412:1
position: 305412
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL129W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ANC1
alternative label: SWP29
alternative label: TAF30
alternative label: TFG3
gene: TAF14
locus tag: YPL129W
gene synonym: ANC1; SWP29; TAF30; TFG3
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:35970389]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005669 transcription factor TFIID complex [PMID:10788514|PMID:15448131]
experiment: EXISTENCE:direct assay:GO:0005674 transcription factor TFIIF complex [PMID:12242279|PMID:15896708|PMID:7995524]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:12887900]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:12138208|PMID:15448131]
experiment: EXISTENCE:direct assay:GO:0006367 transcription initiation at RNA polymerase II promoter [PMID:35970389|PMID:1331084]
experiment: EXISTENCE:direct assay:GO:0016251 RNA polymerase II general transcription initiation factor activity [PMID:14749386]
experiment: EXISTENCE:direct assay:GO:0016514 SWI/SNF complex [PMID:18644858]
experiment: EXISTENCE:direct assay:GO:0016592 mediator complex [PMID:8187178]
experiment: EXISTENCE:direct assay:GO:0031011 Ino80 complex [PMID:12887900]
experiment: EXISTENCE:direct assay:GO:0033100 NuA3 histone acetyltransferase complex [PMID:10817755|PMID:17157260]
experiment: EXISTENCE:direct assay:GO:1990467 NuA3a histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:direct assay:GO:1990468 NuA3b histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:physical interaction:GO:0005674 transcription factor TFIIF complex [PMID:15896708]
experiment: EXISTENCE:physical interaction:GO:0031011 Ino80 complex [PMID:24034245]
note: Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes; involved in RNA polymerase II transcription initiation and in chromatin modification; serves as an additional DNA binding domain for the complex; contains a YEATS domain
codon start: 1
product: TATA-binding protein-associated factor TAF14
translation: MVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQIPLNKPLLTEELAKSGSTEETTANTGTIGKRRTTTNTTAEPKAKRAKTGSASTVKGSVDLEKLAFGLTKLNEDDLVGVVQMVTDNKTPEMNVTNNVEEGEFIIDLYSLPEGLLKSLWDYVKKNTE
SIO_010081: YPL129W
subclass of: SO_0000673
so part of: YPL129W
location: join(305298..305306,305412..306137)
location: region:305298-306137:1
so has part: feature:305298-305306:1:exon
so has part: feature:305412-306137:1:exon

NP_015196.1
type: Protein
SIO_000068: ncbiprotein

S000006050
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:305298-305306:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:305412-306137:1:exon

YPL128C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPI16
gene: TBF1
locus tag: YPL128C
gene synonym: LPI16
so part of: sequence
location: complement(<306533..>308221)
location: region:306533-308221:-1
so has part: feature:306533-308221:-1:exon
subclass of: SO_0000010

855975
type: Gene
SIO_000068: ncbigene

position:306533:-1
position: 306533
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:308221:-1
position: 308221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:306533-308221:-1:exon

YPL128C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPI16
gene: TBF1
locus tag: YPL128C
gene synonym: LPI16
product: Tbf1p
transcript id: NM_001183942.1
SIO_010081: YPL128C
subclass of: SO_0000673
so part of: YPL128C
location: complement(<306533..>308221)
location: region:306533-308221:-1
so has part: feature:306533-308221:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:306533-308221:-1:exon

YPL128C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPI16
gene: TBF1
locus tag: YPL128C
gene synonym: LPI16
experiment: EXISTENCE:direct assay:GO:0000781 chromosome, telomeric region [PMID:20513435]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:20513435]
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:20513435]
experiment: EXISTENCE:direct assay:GO:0001015 snoRNA transcription by RNA polymerase II [PMID:20513435]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0010833 telomere maintenance via telomere lengthening [PMID:17917674]
experiment: EXISTENCE:direct assay:GO:0031936 negative regulation of chromatin silencing [PMID:11258704]
experiment: EXISTENCE:direct assay:GO:0042162 telomeric DNA binding [PMID:20513435]
experiment: EXISTENCE:direct assay:GO:0043035 chromatin insulator sequence binding [PMID:11258704]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:23222485]
experiment: EXISTENCE:genetic interaction:GO:0032211 negative regulation of telomere maintenance via telomerase [PMID:16467854]
experiment: EXISTENCE:mutant phenotype:GO:0001015 snoRNA transcription by RNA polymerase II [PMID:20513435]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:23222485]
note: Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation; involved in nucleosome displacement during double-strand break repair
codon start: 1
product: Tbf1p
translation: MDSQVPNNNESLNRFNDIIQSLPARTRLTICSLCLLDNISTQLLRFLILNANSPNIIAVLTDQTAFLSSGETEIFQTLVKLFKQIRMIYHTRSPLLSVHDVAPGLWFPNSPPPLILRGHEAFIITAIRKANLLTFLLTSLNCLNYGFELLQSIFLDIFCPNTNTVGNNSLEQSGKFLKSQAILYLDLKTQAYIAGLKEFQDETNEISLEKKQELLDLIFPSNLADILVQRRTGDSGDITLLTPSEKDFVERCDRRRENLKIVQDFNSLTQSYEWAQFIRELLDYCNKNMGLIIWGRKGRGKSPLYDFDVNEFDPQVLFSTGTRTVEFMDDQNQPSSASAFLSTARPNHYSTHTPTTDVSSKNPAITQSIVDAAVAASMSNSSSGPHSSHNNSSNSNNNGSIGLRKPKAKRTWSKEEEEALVEGLKEVGPSWSKILDLYGPGGKITENLKNRTQVQLKDKARNWKLQYLKSGKPLPDYLIKVTGNLEKIYKAKKKFSQSPNSSTIMEQNLSQHPSSAASATEDTQTHQEDSHGQNSDNMPSNGLFGNSTSDNTGFDPHLEDGM
SIO_010081: YPL128C
subclass of: SO_0000673
so part of: YPL128C
location: complement(306533..308221)
location: region:306533-308221:-1
so has part: feature:306533-308221:-1:exon

NP_015197.1
type: Protein
SIO_000068: ncbiprotein

S000006049
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:306533-308221:-1:exon

YPL127C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HHO1
locus tag: YPL127C
so part of: sequence
location: complement(<308828..>309604)
location: region:308828-309604:-1
so has part: feature:308828-309604:-1:exon
subclass of: SO_0000010

855976
type: Gene
SIO_000068: ncbigene

position:308828:-1
position: 308828
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:309604:-1
position: 309604
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:308828-309604:-1:exon

YPL127C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HHO1
locus tag: YPL127C
product: histone H1
transcript id: NM_001183941.1
SIO_010081: YPL127C
subclass of: SO_0000673
so part of: YPL127C
location: complement(<308828..>309604)
location: region:308828-309604:-1
so has part: feature:308828-309604:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:308828-309604:-1:exon

YPL127C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HHO1
locus tag: YPL127C
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:22586276]
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:11574687]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9046096|PMID:11914276]
experiment: EXISTENCE:genetic interaction:GO:0031936 negative regulation of chromatin silencing [PMID:19017647]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:11574687]
experiment: EXISTENCE:mutant phenotype:GO:0030261 chromosome condensation [PMID:22586276]
experiment: EXISTENCE:mutant phenotype:GO:0045910 negative regulation of DNA recombination [PMID:12820979]
experiment: EXISTENCE:mutant phenotype:GO:2000779 regulation of double-strand break repair [PMID:31821952]
note: Histone H1, linker histone with roles in meiosis and sporulation; decreasing levels early in sporulation may promote meiosis, and increasing levels during sporulation facilitate compaction of spore chromatin; binds to promoters and within genes in mature spores; may be recruited by Ume6p to promoter regions, contributing to transcriptional repression outside of meiosis; suppresses DNA repair involving homologous recombination
codon start: 1
product: histone H1
translation: MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST
SIO_010081: YPL127C
subclass of: SO_0000673
so part of: YPL127C
location: complement(308828..309604)
location: region:308828-309604:-1
so has part: feature:308828-309604:-1:exon

NP_015198.1
type: Protein
SIO_000068: ncbiprotein

S000006048
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:308828-309604:-1:exon

YPL126W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: UTP17
gene: NAN1
locus tag: YPL126W
gene synonym: UTP17
so part of: sequence
location: <310210..>312900
location: region:310210-312900:1
so has part: feature:310210-312900:1:exon
subclass of: SO_0000010

855977
type: Gene
SIO_000068: ncbigene

position:310210:1
position: 310210
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:312900:1
position: 312900
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:310210-312900:1:exon

YPL126W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: UTP17
gene: NAN1
locus tag: YPL126W
gene synonym: UTP17
product: Nan1p
transcript id: NM_001183940.1
SIO_010081: YPL126W
subclass of: SO_0000673
so part of: YPL126W
location: <310210..>312900
location: region:310210-312900:1
so has part: feature:310210-312900:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:310210-312900:1:exon

YPL126W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: UTP17
gene: NAN1
locus tag: YPL126W
gene synonym: UTP17
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12068309]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:12068309]
experiment: EXISTENCE:direct assay:GO:0033553 rDNA heterochromatin [PMID:15489292]
experiment: EXISTENCE:direct assay:GO:0034455 t-UTP complex [PMID:17515605]
experiment: EXISTENCE:direct assay:GO:0034511 U3 snoRNA binding [PMID:12068309]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:12068309]
experiment: EXISTENCE:mutant phenotype:GO:0045943 positive regulation of transcription by RNA polymerase I [PMID:15489292]
note: U3 snoRNP protein; component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA; localizes to nucleolus and peroxisomes
codon start: 1
product: Nan1p
translation: MTQSLGIEQYKLSVVSGGKPALNNLSSVTGNKNIARLSQDQRNYIIPFNNQIKVYSVETRQCVKTLKFANNSLLSGIFLQEEENNESIVKILLGDITVPQQEDAHLITVFTNNGHVIVLNYKGKLVESPKHFKISLADEKLANVFHSEGNYRILTTFKDPSQKAHNSLQSYRLYALTFDDAKKQFEVAHQAEWHNVILSNISSNGKLLAHMCKDVSTKDHEHKSISVVSLFDDSVNLSFPLGSILSSQTQSLSYNTRYVSSMAIDNMGQQLAVGFASGVISIVSLADLQIRLLKWHIDSVLSLSFSHDGSYLLSGGWEKVMSLWQLETNSQQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENNSNSDYQFLLLNASDLTSKLSINGPLPVFNSTIKHIQQPISAMNTKNSNSITSLNHSKKKQSRKLIKSRRQDFTTNVEINPINKNLYFPHISAVQIFDFYKNEQVNYQYLTSGVNNSMGKVRFELNLQDPIITDLKFTKDGQWMITYEIEYPPNDLLSSKDLTHILKFWTKNDNETNWNLKTKVINPHGISVPITKILPSPRSVNNSQGCLTADNNGGLKFWSFDSHESNWCLKKISLPNFNHFSNSVSLAWSQDGSLIFHGFDDKLQILDFDTFKKFESLENTKTVSEFTLDSEIQTVKLINDTNLIVATRTTLNAINLLRGQVINSFDLYPFVNGVYKNGHMDRLITCDERTGNIALVINQQLTDLDGVPTINYKSRIIIFDSDLSTKLGNFTHHEYISWIGWNYDTDFIFLDIESTLGVVGTTVNTQLSDEVNNEGILDGLVSNTITTSASNSDIFAEQLHKLSSRGKKSDTRDKNTNDNDEDEEDIALEFINGEKKDKLVNMNSFTSMFDNIQNVQMDTFFDRVMKVLT
SIO_010081: YPL126W
subclass of: SO_0000673
so part of: YPL126W
location: 310210..312900
location: region:310210-312900:1
so has part: feature:310210-312900:1:exon

NP_015199.1
type: Protein
SIO_000068: ncbiprotein

S000006047
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:310210-312900:1:exon

YPL125W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPH2
gene: KAP120
locus tag: YPL125W
gene synonym: LPH2
so part of: sequence
location: <313388..>316486
location: region:313388-316486:1
so has part: feature:313388-316486:1:exon
subclass of: SO_0000010

855978
type: Gene
SIO_000068: ncbigene

position:313388:1
position: 313388
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316486:1
position: 316486
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:313388-316486:1:exon

YPL125W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPH2
gene: KAP120
locus tag: YPL125W
gene synonym: LPH2
product: Kap120p
transcript id: NM_001183939.1
SIO_010081: YPL125W
subclass of: SO_0000673
so part of: YPL125W
location: <313388..>316486
location: region:313388-316486:1
so has part: feature:313388-316486:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:313388-316486:1:exon

YPL125W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPH2
gene: KAP120
locus tag: YPL125W
gene synonym: LPH2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16581791|PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0006606 protein import into nucleus [PMID:20219973]
experiment: EXISTENCE:direct assay:GO:0008139 nuclear localization sequence binding [PMID:20219973]
experiment: EXISTENCE:direct assay:GO:0061608 nuclear import signal receptor activity [PMID:20219973]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:20219973|PMID:16581791]
experiment: EXISTENCE:mutant phenotype:GO:0061608 nuclear import signal receptor activity [PMID:20219973]
experiment: EXISTENCE:physical interaction:GO:0006606 protein import into nucleus [PMID:16581791]
note: Karyopherin responsible for the nuclear import of Rpf1p; Rpf1p is a ribosome maturation factor
codon start: 1
product: Kap120p
translation: MASSLNELNLVQVLEQASNPQHIRSDVQKLAEQQLRQWETQAGFHYLLQSIYLNLSNSLQIRWLAVIQFKNGVDKYWRSTRINAIPKDEKASIRGRLFEMIDEQNNQLCIQNAQASARIARLDFPVEWPTLFEDLENLLNDEIIRKDSVKIYNILMHINQIVKVLGTARIGRCRPAMQSKVPLILPLIVRIYLQSFEEWTTSSNLNYEDLSSLQVSYLALKVLRRIICEGYDRPQTDQSVCDFIKLSVSHFEMLISNHENFKKFDIYEKFIKCLGKLYFNLVTGSPANFILLPCSTQILITYTRLIFDKAPKVYRENSDVTGDFWEQTAIRGLLILKRVINFIHKKGAITLKARSDKLTIDASINKINTEFLNENLITRLVDTLMEWYLRLRPTELENWFMDPEEWINEQMATSYEYQIRPCAENVFQDLMNTFSELLVPYLLKKIENDASKLSNSLDDFLRKDAIYASFQLSASAVSEMVDFDRLLIQVFLPEATNTNISGDELRIIRRRVALIINEWSTVKCSEESKSLCYKLFTNFLTDEDDKVVLLTTVQTVRTMVDDWNFNKDTFQPFLTENVHLLLRKILPSVSLTETRLYVLNTLSDIIIQTKPLISRDLLVEILQIIPNLWEIATNNASEAILANALLRLLRNLVSSLGSQSHLTWDIAIPVVALACDPSSMQYQLLSEDGYELWGMLLQNFSSHDQEFDDKFVELVPFLKYGIETHTEILPTLLEIIKSYALILNPVDFFSNNTFQDIFKQMSKYLLKLREDSFQLVLEIWEILILSNESDYENLLLQKFYETGVLSALFDAIFLEEAPSSYLCSQIIQIIARISYVNPDALMTFLATYHDNLPTSNENARMPESIRKIVSKDQTYDSVVNKLLTGWIVCFRDIFDPKFKKVHILGISSLLRTGLVPILTEFSSIASLWIEMLEEINETNRGDCEKYHLNDIVTEQSIAFHPLTAEQLRYHQLCKNNDPVHNISLKDFISQSMEYLESHLGVERYQEFLKTINPSLLENLQMFLSIQPQEARP
SIO_010081: YPL125W
subclass of: SO_0000673
so part of: YPL125W
location: 313388..316486
location: region:313388-316486:1
so has part: feature:313388-316486:1:exon

NP_015200.1
type: Protein
SIO_000068: ncbiprotein

S000006046
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:313388-316486:1:exon

YPL124W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPH3
alternative label: NIP29
gene: SPC29
locus tag: YPL124W
gene synonym: LPH3; NIP29
so part of: sequence
location: <316755..>317516
location: region:316755-317516:1
so has part: feature:316755-317516:1:exon
subclass of: SO_0000010

855979
type: Gene
SIO_000068: ncbigene

position:316755:1
position: 316755
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:317516:1
position: 317516
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:316755-317516:1:exon

YPL124W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPH3
alternative label: NIP29
gene: SPC29
locus tag: YPL124W
gene synonym: LPH3; NIP29
product: Spc29p
transcript id: NM_001183938.1
SIO_010081: YPL124W
subclass of: SO_0000673
so part of: YPL124W
location: <316755..>317516
location: region:316755-317516:1
so has part: feature:316755-317516:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:316755-317516:1:exon

YPL124W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPH3
alternative label: NIP29
gene: SPC29
locus tag: YPL124W
gene synonym: LPH3; NIP29
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0061493 central plaque of mitotic spindle pole body [PMID:10339566]
experiment: EXISTENCE:mutant phenotype:GO:1903087 mitotic spindle pole body duplication [PMID:10330408|PMID:10339566]
note: Inner plaque spindle pole body (SPB) component; links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication
codon start: 1
product: Spc29p
translation: MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREENFSSNTSELGNKKHYRAQERMSSPLHRLSPTGKSDDRKVKSPLDDKLRRQLREGNTRLPPPPFSSYGMPPTNRSNLDRIRRRTSSPVRTDKFASQNVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFILNSISDRGDKNFASLEHSRSFSGFPTNKTYGLQMGGLYENDMPYRRSSDNINKEGAREDRSSQIHIENESTEDILKILSSSFHN
SIO_010081: YPL124W
subclass of: SO_0000673
so part of: YPL124W
location: 316755..317516
location: region:316755-317516:1
so has part: feature:316755-317516:1:exon

NP_015201.1
type: Protein
SIO_000068: ncbiprotein

S000006045
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:316755-317516:1:exon

YPL123C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RNY1
locus tag: YPL123C
so part of: sequence
location: complement(<317641..>318945)
location: region:317641-318945:-1
so has part: feature:317641-318945:-1:exon
subclass of: SO_0000010

855980
type: Gene
SIO_000068: ncbigene

position:317641:-1
position: 317641
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:318945:-1
position: 318945
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:317641-318945:-1:exon

YPL123C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RNY1
locus tag: YPL123C
product: ribonuclease T2
transcript id: NM_001183937.1
SIO_010081: YPL123C
subclass of: SO_0000673
so part of: YPL123C
location: complement(<317641..>318945)
location: region:317641-318945:-1
so has part: feature:317641-318945:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:317641-318945:-1:exon

YPL123C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RNY1
locus tag: YPL123C
EC number: 4.6.1.19
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:24102742]
experiment: EXISTENCE:direct assay:GO:0004521 endoribonuclease activity [PMID:11158587]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:11158587]
experiment: EXISTENCE:direct assay:GO:0005773 vacuole [PMID:19332891]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:19332891|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006915 apoptotic process [PMID:19332891]
experiment: EXISTENCE:mutant phenotype:GO:0000902 cell morphogenesis [PMID:11158587]
experiment: EXISTENCE:mutant phenotype:GO:0004521 endoribonuclease activity [PMID:19332891]
experiment: EXISTENCE:mutant phenotype:GO:0006401 RNA catabolic process [PMID:19332891]
note: Vacuolar RNase of the T(2) family; relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; required for tRNA-specific translational pausing during oxidative stress; promotes apoptosis under stress conditions and this function is independent of Rny1p catalytic activity
codon start: 1
product: ribonuclease T2
translation: MLLKNLHSLLQLPIFSNGADKGIEPNCPINIPLSCSNKTDIDNSCCFEYPGGIFLQTQFWNYFPSKNDLNETELVKELGPLDSFTIHGLWPDNCHGGYQQFCNRSLQIDDVYYLLHDKKFNNNDTSLQISGEKLLEYLDLYWKSNNGNHESLWIHEFNKHGTCISTIRPECYTEWGANSVDRKRAVYDYFRITYNLFKKLDTFSTLEKNNIVPSVDNSYSLEQIEAALSKEFEGKKVFIGCDRHNSLNEVWYYNHLKGSLLSEMFVPMDSLAIRTNCKKDGIKFFPKGYVPTFRRRPNKGARYRGVVRLSNINNGDQMQGFLIKNGHWMSQGTPANYELIKSPYGNYYLRTNQGFCDIISSSSNELVCKFRNIKDAGQFDFDPTKGGDGYIGYSGNYNWGGDTYPRRRNQSPIFSVDDEQNSKKYKFKLKFIKN
SIO_010081: YPL123C
subclass of: SO_0000673
so part of: YPL123C
location: complement(317641..318945)
location: region:317641-318945:-1
so has part: feature:317641-318945:-1:exon

NP_015202.1
type: Protein
SIO_000068: ncbiprotein

S000006044
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:317641-318945:-1:exon

YPL122C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TFB2
locus tag: YPL122C
so part of: sequence
location: complement(<319226..>320767)
location: region:319226-320767:-1
so has part: feature:319226-320767:-1:exon
subclass of: SO_0000010

855981
type: Gene
SIO_000068: ncbigene

position:319226:-1
position: 319226
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:320767:-1
position: 320767
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:319226-320767:-1:exon

YPL122C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TFB2
locus tag: YPL122C
product: TFIIH/NER complex subunit TFB2
transcript id: NM_001183936.1
SIO_010081: YPL122C
subclass of: SO_0000673
so part of: YPL122C
location: complement(<319226..>320767)
location: region:319226-320767:-1
so has part: feature:319226-320767:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:319226-320767:-1:exon

YPL122C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TFB2
locus tag: YPL122C
experiment: EXISTENCE:direct assay:GO:0000439 transcription factor TFIIH core complex [PMID:14500720|PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:19897425]
experiment: EXISTENCE:direct assay:GO:0005675 transcription factor TFIIH holo complex [PMID:19818408|PMID:27381459]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:19450536|PMID:19679665]
experiment: EXISTENCE:mutant phenotype:GO:0006289 nucleotide-excision repair [PMID:9235928]
experiment: EXISTENCE:physical interaction:GO:0000112 nucleotide-excision repair factor 3 complex [PMID:10681587]
note: Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH
codon start: 1
product: TFIIH/NER complex subunit TFB2
translation: MSDYSLKHSVTQYLEEIPQQVQNRLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLLDLDKWVNSNGKLQFQNAIKSMKSLHLLIPNKSSGTLMINLNPTFKISLRNALTGGEVQNSFGVVVEENVVSLDLLDEYSANKWETILHFMVGTPLAKIPSEKVLNLLKHSKLMEEVNSTGEFKITNEGFQFLLQEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKIDALSETQRIMLQDMRDYGLVFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDSVLRQNREEPSVNEDGANGKSTTDITTSDDLNKAGLKNQDIPDGSLIVETNFKIYSYSNSPLQIAVLSLFVHLKARFVNMVLGQITRESIRRALTNGITADQIIAYLETHAHPQMRRLAEEKLEKKLELDPNCKEPLQVLPPTVVDQIRLWQLELDRVITYEGSLYSDFETSQEYNLLSKYAQDIGVLLWKDDKKKKFFISKEGNSQVLDFAKRKLKKKQ
SIO_010081: YPL122C
subclass of: SO_0000673
so part of: YPL122C
location: complement(319226..320767)
location: region:319226-320767:-1
so has part: feature:319226-320767:-1:exon

NP_015203.1
type: Protein
SIO_000068: ncbiprotein

S000006043
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:319226-320767:-1:exon

YPL121C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPH6
gene: MEI5
locus tag: YPL121C
gene synonym: LPH6
so part of: sequence
location: complement(<320962..>321630)
location: region:320962-321630:-1
so has part: feature:320962-321630:-1:exon
subclass of: SO_0000010

855982
type: Gene
SIO_000068: ncbigene

position:320962:-1
position: 320962
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:321630:-1
position: 321630
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:320962-321630:-1:exon

YPL121C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPH6
gene: MEI5
locus tag: YPL121C
gene synonym: LPH6
product: Mei5p
transcript id: NM_001183935.1
SIO_010081: YPL121C
subclass of: SO_0000673
so part of: YPL121C
location: complement(<320962..>321630)
location: region:320962-321630:-1
so has part: feature:320962-321630:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:320962-321630:-1:exon

YPL121C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPH6
gene: MEI5
locus tag: YPL121C
gene synonym: LPH6
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:15579681|PMID:15620352]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0000707 meiotic DNA recombinase assembly [PMID:15579681|PMID:15620352]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:15579681|PMID:15620352]
note: Meiosis-specific protein involved in meiotic recombination; involved in DMC1-dependent meiotic recombination; forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p
codon start: 1
product: Mei5p
translation: MHNQEEWLDKDKTLVNEEENTCINHSYTKKDTNNYRVGKSGIKDLKKPTNQKEIAIKNRELTKQLTLLRQENNHLQQACKILSENKIIENRKSIEKWRTICEMELSFILNSTLIKINRMGGYKDFLEKEMEAKKRRLEYQIDNGMEDQICEIKESDDFRQLSEVEKQEWESQMNEQLKELEKKKIAELEKLNKVLHDSEGKDFGMAELCTRLKLDYSLIFPQ
SIO_010081: YPL121C
subclass of: SO_0000673
so part of: YPL121C
location: complement(320962..321630)
location: region:320962-321630:-1
so has part: feature:320962-321630:-1:exon

NP_015204.1
type: Protein
SIO_000068: ncbiprotein

S000006042
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:320962-321630:-1:exon

YPL120W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APG6
alternative label: ATG6
alternative label: VPT30
gene: VPS30
locus tag: YPL120W
gene synonym: APG6; ATG6; VPT30
so part of: sequence
location: <322071..>323744
location: region:322071-323744:1
so has part: feature:322071-323744:1:exon
subclass of: SO_0000010

855983
type: Gene
SIO_000068: ncbigene

position:322071:1
position: 322071
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:323744:1
position: 323744
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:322071-323744:1:exon

YPL120W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APG6
alternative label: ATG6
alternative label: VPT30
gene: VPS30
locus tag: YPL120W
gene synonym: APG6; ATG6; VPT30
product: beclin 1
transcript id: NM_001183934.1
SIO_010081: YPL120W
subclass of: SO_0000673
so part of: YPL120W
location: <322071..>323744
location: region:322071-323744:1
so has part: feature:322071-323744:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:322071-323744:1:exon

YPL120W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APG6
alternative label: ATG6
alternative label: VPT30
gene: VPS30
locus tag: YPL120W
gene synonym: APG6; ATG6; VPT30
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19001347]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9105038]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I [PMID:11157979]
experiment: EXISTENCE:direct assay:GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II [PMID:11157979]
experiment: EXISTENCE:direct assay:GO:0120095 vacuole-isolation membrane contact site [PMID:23549786]
experiment: EXISTENCE:genetic interaction:GO:0042147 retrograde transport, endosome to Golgi [PMID:12244127]
experiment: EXISTENCE:mutant phenotype:GO:0006661 phosphatidylinositol biosynthetic process [PMID:12244127]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:22437838]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11157979|PMID:32788210]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:21121900]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:9105038|PMID:9712845]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0042147 retrograde transport, endosome to Golgi [PMID:12244127]
experiment: EXISTENCE:mutant phenotype:GO:0045324 late endosome to vacuole transport [PMID:11157979]
note: Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy, Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has novel globular fold essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of higher eukaryote gene Beclin 1; human BECN1 can complement yeast null mutant
codon start: 1
product: beclin 1
translation: MKCQTCHLPLQLDPSLEGLSLTQRNLLLSNNSIITATNENVISNKGIEAADNCGPQIPKERLRRLGEIQNIKDLNLKDDKLITDSFVFLNHDDDDNANITSNSREDQRYGNANGNDNKKANSDTSDGTSTFRDHDEEEQEATDEDENQQIQLNSKTLSTQVNAMTNVFNILSSQTNIDFPICQDCCNILINRLKSEYDDAIKERDTYAQFLSKLESQNKEISESNKEKQYSHNLSEKENLKKEEERLLDQLLRLEMTDDDLDGELVRLQEKKVQLENEKLQKLSDQNLMDLNNIQFNKNLQSLKLQYELSLNQLDKLRKINIFNATFKISHSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKRMVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEITRQLSTIASSYSSQTLTTSQDESSMNNANDVENSTSILELPYIMNKDKINGLSVKLHGSSPNLEWTTAMKFLLTNVKWLLAFSSNLLSKSITLSPTVNYNDKTISGN
SIO_010081: YPL120W
subclass of: SO_0000673
so part of: YPL120W
location: 322071..323744
location: region:322071-323744:1
so has part: feature:322071-323744:1:exon

NP_015205.1
type: Protein
SIO_000068: ncbiprotein

S000006041
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:322071-323744:1:exon

YPL119C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL119C-A
so part of: sequence
location: complement(<324024..>324287)
location: region:324024-324287:-1
so has part: feature:324024-324287:-1:exon
subclass of: SO_0000010

1466520
type: Gene
SIO_000068: ncbigene

position:324024:-1
position: 324024
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:324287:-1
position: 324287
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324024-324287:-1:exon

YPL119C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL119C-A
product: uncharacterized protein
transcript id: NM_001184670.1
SIO_010081: YPL119C-A
subclass of: SO_0000673
so part of: YPL119C-A
location: complement(<324024..>324287)
location: region:324024-324287:-1
so has part: feature:324024-324287:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:324024-324287:-1:exon

YPL119C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL119C-A
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MHPLVDELTLSRYLTHGTSVLSSSLYSVAFFLFFFPNFLFFCSCPNHKWVSLPFIGMDILEALCFYREGKIRNIFEIGGLLLQSFYN
SIO_010081: YPL119C-A
subclass of: SO_0000673
so part of: YPL119C-A
location: complement(324024..324287)
location: region:324024-324287:-1
so has part: feature:324024-324287:-1:exon

NP_878181.1
type: Protein
SIO_000068: ncbiprotein

S000028859
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:324024-324287:-1:exon

YPL119C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPH8
gene: DBP1
locus tag: YPL119C
gene synonym: LPH8
so part of: sequence
location: complement(<324411..>326264)
location: region:324411-326264:-1
so has part: feature:324411-326264:-1:exon
subclass of: SO_0000010

855984
type: Gene
SIO_000068: ncbigene

position:324411:-1
position: 324411
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:326264:-1
position: 326264
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324411-326264:-1:exon

YPL119C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPH8
gene: DBP1
locus tag: YPL119C
gene synonym: LPH8
product: putative DEAD-box ATP-dependent RNA helicase DBP1
transcript id: NM_001183933.1
SIO_010081: YPL119C
subclass of: SO_0000673
so part of: YPL119C
location: complement(<324411..>326264)
location: region:324411-326264:-1
so has part: feature:324411-326264:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:324411-326264:-1:exon

YPL119C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPH8
gene: DBP1
locus tag: YPL119C
gene synonym: LPH8
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0003727 single-stranded RNA binding [PMID:31299079]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:31299079]
experiment: EXISTENCE:direct assay:GO:0033677 DNA/RNA helicase activity [PMID:21884706]
experiment: EXISTENCE:direct assay:GO:1901195 positive regulation of formation of translation preinitiation complex [PMID:31299079]
experiment: EXISTENCE:genetic interaction:GO:0006413 translational initiation [PMID:31299079]
experiment: EXISTENCE:mutant phenotype:GO:0006413 translational initiation [PMID:14763975]
note: ATP-dependent RNA helicase of the DEAD-box protein family; accelerates eIF4F-dependent assembly of 48S translation preinitiation complex (PIC), stimulating recruitment of mRNAs with long, structured 5'-UTRs; cooperates with DEAD-box RNA helicase and paralog Ded1p, stimulating PIC attachment and highly processive scanning by the 40S ribosomal subunit; protein abundance increases in response to DNA replication stress
codon start: 1
product: putative DEAD-box ATP-dependent RNA helicase DBP1
translation: MADLPQKVSNLSINNKENGGGGGKSSYVPPHLRSRGKPSFERSTPKQEDKVTGGDFFRRAGRQTGNNGGFFGFSKERNGGTSANYNRGGSSNYKSSGNRWVNGKHIPGPKNAKLEAELFGVHDDPDYHSSGIKFDNYDNIPVDASGKDVPEPILDFSSPPLDELLMENIKLASFTKPTPVQKYSIPIVTKGRDLMACAQTGSGKTGGFLFPLFTELFRSGPSPVPEKAQSFYSRKGYPSALVLAPTRELATQIFEEARKFTYRSWVRPCVVYGGAPIGNQMREVDRGCDLLVATPGRLNDLLERGKVSLANIKYLVLDEADRMLDMGFEPQIRHIVEECDMPSVENRQTLMFSATFPVDIQHLARDFLDNYIFLSVGRVGSTSENITQRILYVDDMDKKSALLDLLSAEHKGLTLIFVETKRMADQLTDFLIMQNFKATAIHGDRTQAERERALSAFKANVADILVATAVAARGLDIPNVTHVINYDLPSDIDDYVHRIGRTGRAGNTGVATSFFNSNNQNIVKGLMEILNEANQEVPTFLSDLSRQNSRGGRTRGGGGFFNSRNNGSRDYRKHGGNGSFGSTRPRNTGTSNWGSIGGGFRNDNEKNGYGNSNASWW
SIO_010081: YPL119C
subclass of: SO_0000673
so part of: YPL119C
location: complement(324411..326264)
location: region:324411-326264:-1
so has part: feature:324411-326264:-1:exon

NP_015206.1
type: Protein
SIO_000068: ncbiprotein

S000006040
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:324411-326264:-1:exon

YPL118W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bS1m
gene: MRP51
locus tag: YPL118W
gene synonym: bS1m
so part of: sequence
location: <326628..>327662
location: region:326628-327662:1
so has part: feature:326628-327662:1:exon
subclass of: SO_0000010

855985
type: Gene
SIO_000068: ncbigene

position:326628:1
position: 326628
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:327662:1
position: 327662
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:326628-327662:1:exon

YPL118W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bS1m
gene: MRP51
locus tag: YPL118W
gene synonym: bS1m
product: mitochondrial 37S ribosomal protein MRP51
transcript id: NM_001183932.1
SIO_010081: YPL118W
subclass of: SO_0000673
so part of: YPL118W
location: <326628..>327662
location: region:326628-327662:1
so has part: feature:326628-327662:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:326628-327662:1:exon

YPL118W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bS1m
gene: MRP51
locus tag: YPL118W
gene synonym: bS1m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:11278769|PMID:9528754]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:11278769|PMID:9528754]
experiment: EXISTENCE:genetic interaction:GO:0070124 mitochondrial translational initiation [PMID:9528754]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:9528754]
note: Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences
codon start: 1
product: mitochondrial 37S ribosomal protein MRP51
translation: MTLAELLGRSRIAQVANNHKPLTYTGKKFHPTHQIIETKPSTLYRQEWGLKSAIPSKIKSRYLVYNDLDTLERITTFEPRGGTQWNRLRFQEMGVPIVSNIGRQNPFFKYISRPEDESHAKLSLFKEMKGDTDISPAAMKKRLKKITALIRSFQDEFKEWLVENHPDELKLNSNKLEDYVVKFLNKKLETKTNKKFNTEIIGTGGLSYSLPGKLKNSPNGVIQRTVVPGRILNVVKENNDNKWLAAIGGFVADVVFFQSPPSSFNSMGDFIRMKTFLFEILEASMEKNGSVSMHARLLEPQNDKTREFFNKRPIYKPLTSRRARRPSVGNIQEANNLLNIIKGN
SIO_010081: YPL118W
subclass of: SO_0000673
so part of: YPL118W
location: 326628..327662
location: region:326628-327662:1
so has part: feature:326628-327662:1:exon

NP_015207.1
type: Protein
SIO_000068: ncbiprotein

S000006039
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:326628-327662:1:exon

YPL117C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BOT2
alternative label: LPH10
gene: IDI1
locus tag: YPL117C
gene synonym: BOT2; LPH10
so part of: sequence
location: complement(<327864..>328730)
location: region:327864-328730:-1
so has part: feature:327864-328730:-1:exon
subclass of: SO_0000010

855986
type: Gene
SIO_000068: ncbigene

position:327864:-1
position: 327864
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:328730:-1
position: 328730
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:327864-328730:-1:exon

YPL117C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BOT2
alternative label: LPH10
gene: IDI1
locus tag: YPL117C
gene synonym: BOT2; LPH10
product: isopentenyl-diphosphate delta-isomerase IDI1
transcript id: NM_001183931.1
SIO_010081: YPL117C
subclass of: SO_0000673
so part of: YPL117C
location: complement(<327864..>328730)
location: region:327864-328730:-1
so has part: feature:327864-328730:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:327864-328730:-1:exon

YPL117C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BOT2
alternative label: LPH10
gene: IDI1
locus tag: YPL117C
gene synonym: BOT2; LPH10
EC number: 5.3.3.2
experiment: EXISTENCE:direct assay:GO:0004452 isopentenyl-diphosphate delta-isomerase activity [PMID:2681212]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006696 ergosterol biosynthetic process [PMID:2681212]
experiment: EXISTENCE:direct assay:GO:0045337 farnesyl diphosphate biosynthetic process [PMID:7858969]
note: Isopentenyl diphosphate:dimethylallyl diphosphate isomerase; catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability; isopentenyl diphosphate:dimethylallyl diphosphate isomerase is also known as IPP isomerase
codon start: 1
product: isopentenyl-diphosphate delta-isomerase IDI1
translation: MTADNNSMPHGAVSSYAKLVQNQTPEDILEEFPEIIPLQQRPNTRSSETSNDESGETCFSGHDEEQIKLMNENCIVLDWDDNAIGAGTKKVCHLMENIEKGLLHRAFSVFIFNEQGELLLQQRATEKITFPDLWTNTCCSHPLCIDDELGLKGKLDDKIKGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPSNEPWGEHEIDYILFYKINAKENLTVNPNVNEVRDFKWVSPNDLKTMFADPSYKFTPWFKIICENYLFNWWEQLDDLSEVENDRQIHRML
SIO_010081: YPL117C
subclass of: SO_0000673
so part of: YPL117C
location: complement(327864..328730)
location: region:327864-328730:-1
so has part: feature:327864-328730:-1:exon

NP_015208.1
type: Protein
SIO_000068: ncbiprotein

S000006038
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:327864-328730:-1:exon

YPL116W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HOS3
locus tag: YPL116W
so part of: sequence
location: <329606..>331699
location: region:329606-331699:1
so has part: feature:329606-331699:1:exon
subclass of: SO_0000010

855987
type: Gene
SIO_000068: ncbigene

position:329606:1
position: 329606
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:331699:1
position: 331699
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:329606-331699:1:exon

YPL116W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HOS3
locus tag: YPL116W
product: histone deacetylase
transcript id: NM_001183930.1
SIO_010081: YPL116W
subclass of: SO_0000673
so part of: YPL116W
location: <329606..>331699
location: region:329606-331699:1
so has part: feature:329606-331699:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:329606-331699:1:exon

YPL116W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HOS3
locus tag: YPL116W
EC number: 3.5.1.98
experiment: EXISTENCE:direct assay:GO:0004407 histone deacetylase activity [PMID:10535926]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:17706600]
experiment: EXISTENCE:physical interaction:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668]
note: Trichostatin A-insensitive homodimeric histone deacetylase (HDAC); specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats
codon start: 1
product: histone deacetylase
translation: MSSKHSDPLERFYKQFQAFVQNNPNVISAARAAAQIPESAKAVVVLSPYSLQHVFPREWVTKSYRKTIVERPERLLASSMGISAAITMYPSLFTLKSSHQRKGSLMAPHVLKVHGSSWPAELIELCQMADAKLLKGEIEVPDTWNSGDIYLSSKTIKALQGTIGAIETGVDSIFKGPSAEHISNRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINSFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQVVKEIVRGCKPAWKPYKTKRAKDVIRIWAEEVIRLGRAMIPEFDDIIFKDAVNSAPSNSLLKATVEPASTSTIAQRIIRSHRSNASPEKELHENKPRSTEKQEQREIRSDTKVKQLSSNNRAAETQIPFLQQEFSSEDEDEEYVYDEELNKTFNRTVEDITIDDISRHLETLEIEKKGDEDSDHELKEKNWKNSHQRRLQGNGMYKIPSNTKPHRIRQPQNANTPTYDDSDISMISHVSRKHTTRSGGRW
SIO_010081: YPL116W
subclass of: SO_0000673
so part of: YPL116W
location: 329606..331699
location: region:329606-331699:1
so has part: feature:329606-331699:1:exon

NP_015209.1
type: Protein
SIO_000068: ncbiprotein

S000006037
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:329606-331699:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1617; Replication origin; identified in multiple array studies, confirmed by plasmid-based recombinational ARS assay
so part of: sequence
location: 331699..332100
location: region:331699-332100:1
so has part: feature:331699-332100:1:region

S000130199
type: SGD
SIO_000068: sgd

position:332100:1
position: 332100
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:331699-332100:1:region

YPL115C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BEM3
locus tag: YPL115C
so part of: sequence
location: complement(<332100..>335486)
location: region:332100-335486:-1
so has part: feature:332100-335486:-1:exon
subclass of: SO_0000010

855988
type: Gene
SIO_000068: ncbigene

position:332100:-1
position: 332100
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:335486:-1
position: 335486
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:332100-335486:-1:exon

YPL115C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BEM3
locus tag: YPL115C
product: GTPase-activating protein BEM3
transcript id: NM_001183929.1
SIO_010081: YPL115C
subclass of: SO_0000673
so part of: YPL115C
location: complement(<332100..>335486)
location: region:332100-335486:-1
so has part: feature:332100-335486:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:332100-335486:-1:exon

YPL115C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BEM3
locus tag: YPL115C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:17914457]
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:12455995|PMID:8227021|PMID:8300560|PMID:7498791]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17914457]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:17914457]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:17914457]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:11557775]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:17914457|PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0043547 positive regulation of GTPase activity [PMID:12455995]
experiment: EXISTENCE:genetic interaction:GO:0005096 GTPase activator activity [PMID:7498791]
experiment: EXISTENCE:genetic interaction:GO:0031106 septin ring organization [PMID:14517318]
experiment: EXISTENCE:genetic interaction:GO:0035024 negative regulation of Rho protein signal transduction [PMID:17914457]
experiment: EXISTENCE:mutant phenotype:GO:0030010 establishment of cell polarity [PMID:8013906]
experiment: EXISTENCE:mutant phenotype:GO:0035024 negative regulation of Rho protein signal transduction [PMID:17914457]
experiment: EXISTENCE:physical interaction:GO:0035024 negative regulation of Rho protein signal transduction [PMID:17914457]
note: Rho GTPase activating protein (RhoGAP); involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
codon start: 1
product: GTPase-activating protein BEM3
translation: MTDNLTTTHGGSTTLELLAQYNDHRSKKDKSIEHIEKGTCSGKERNPSYDEIFTENIKLKLQVQEYETEIESLEKVIDMLQKNREASLEVVLEQVQNDSRDSYVNDQSFVLPPRSAERKAHIKSLNLPIPTLSPPLQQGSDVALETSVTPTVPQIGVTSNTSISRKHLQNMILNDEIEANSSFSSPKIINRSVSSPTKIHSEQLASPAASVTYTTSRITIKSPNKGSKSPLQERLRSPQNPNRMTAVINNHLHSPLKASTSNNLDELTESKSQQLTNDAIQKNDRVYSSITSSAYTTGTPTSAAKSPSSLLEVKEGENKALGFSPASKEKLDDFTQLLDSSFGEEDLVNTDSKDPLSIKSTINESLPPPPAPPTFFSPTSSGNIKNSTPLSSHLASPVILNKKDDNFGAQSAKNLKKPVLTSSLPNLSTKLSTTSQNASLPPNPPVESSSKQKQLGETASIHSTNTLNTFSSTPQGSLKTLRRPHASSVSTVKSVAQSLKSDIPLFVQPEDFGTIQIEVLSTLYRDNEDDLSILIAIIDRKSGKEMFKFSKSIHKVRELDVYMKSHVPDLPLPTLPDRQLFQTLSPTKVDTRKNILNQYYTSIFSVPEFPKNVGLKIAQFISTDTVMTPPMMDDNVKDGSLLLRRPKTLTGNSTWRVRYGILRDDVLQLFDKNQLTETIKLRQSSIELIPNLPEDRFGTRNGFLITEHKKSGLSTSTKYYICTETSKERELWLSAFSDYIDPSQSLSLSSSRNANDTDSASHLSAGTHHSKFGNATISATDTPSYVTDLTQEYNNNNNISNSSNNIANSDGIDSNPSSHSNFLASSSGNAEEEKDSRRAKMRSLFPFKKLTGPASAMNHIGITISNDSDSPTSPDSIIKSPSKKLMEVSSSSNSSTGPHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTLNIPISMLQPFITDFACIFQGGEPVKEEEREKVDIHIPQV
SIO_010081: YPL115C
subclass of: SO_0000673
so part of: YPL115C
location: complement(332100..335486)
location: region:332100-335486:-1
so has part: feature:332100-335486:-1:exon

NP_015210.1
type: Protein
SIO_000068: ncbiprotein

S000006036
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:332100-335486:-1:exon

YPL113C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL113C
so part of: sequence
location: complement(<335953..>337143)
location: region:335953-337143:-1
so has part: feature:335953-337143:-1:exon
subclass of: SO_0000010

855990
type: Gene
SIO_000068: ncbigene

position:335953:-1
position: 335953
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:337143:-1
position: 337143
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:335953-337143:-1:exon

YPL113C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL113C
product: glyoxylate reductase
transcript id: NM_001183927.1
SIO_010081: YPL113C
subclass of: SO_0000673
so part of: YPL113C
location: complement(<335953..>337143)
location: region:335953-337143:-1
so has part: feature:335953-337143:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:335953-337143:-1:exon

YPL113C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL113C
experiment: EXISTENCE:mutant phenotype:GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [PMID:17173333]
note: Glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; YPL113C is not an essential gene
codon start: 1
product: glyoxylate reductase
translation: MITSIDIADVTYSAKPRILVPYKTQWEVASHLPEYRKLAERVEFYKYEMSTKDDFVKFLETHRINGFWLTEEFFTVLGNPSSYIEFFPASLKVILVPWVGCDFIDGKLLRSKGITLCNIGPHAADHVTELAIFLAISCFRMTSFWEYCFKYVENGNVEQCKKYISSDSYEIVTDSYHGQEMKFPSRTDKCKPNKDRKVVHLAEKYTVGGKKMESPMNKKVLILGFGSIGQNIGSNLHKVFNMSIEYYKRTGPVQKSLLDYNAKYHSDLDDPNTWKNADLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGLDVFKNEETRVKQELLRRWDVTALPHIGSTVADMVIKQTLITLENVQDIFVEGGDGKYVLN
SIO_010081: YPL113C
subclass of: SO_0000673
so part of: YPL113C
location: complement(335953..337143)
location: region:335953-337143:-1
so has part: feature:335953-337143:-1:exon

NP_015212.1
type: Protein
SIO_000068: ncbiprotein

S000006034
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:335953-337143:-1:exon

YPL112C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PEX25
locus tag: YPL112C
so part of: sequence
location: complement(<337436..>338620)
location: region:337436-338620:-1
so has part: feature:337436-338620:-1:exon
subclass of: SO_0000010

855991
type: Gene
SIO_000068: ncbigene

position:337436:-1
position: 337436
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:338620:-1
position: 338620
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:337436-338620:-1:exon

YPL112C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PEX25
locus tag: YPL112C
product: Pex25p
transcript id: NM_001183926.1
SIO_010081: YPL112C
subclass of: SO_0000673
so part of: YPL112C
location: complement(<337436..>338620)
location: region:337436-338620:-1
so has part: feature:337436-338620:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:337436-338620:-1:exon

YPL112C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PEX25
locus tag: YPL112C
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:22375831]
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:12135984]
experiment: EXISTENCE:mutant phenotype:GO:0007031 peroxisome organization [PMID:12135984]
experiment: EXISTENCE:mutant phenotype:GO:0016558 protein import into peroxisome matrix [PMID:12135984]
note: Peripheral peroxisomal membrane peroxin; required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with Pex27p; PEX25 has a paralog, PEX27, that arose from the whole genome duplication
codon start: 1
product: Pex25p
translation: MSQFGTTDIVSGSETPPYSGASYQDAQDDNTHPHSSDAGAEKFSAGSGSESHTESSRSDDEDSQAKTKMVDNITILKYILDSLSGRDKLAKIIKYALDILKLFIEKSKRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSLLRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKFNKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKSFYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNLKTPKGTYAVLSLGSGLTGLVKLWITTKRSLCSSKD
SIO_010081: YPL112C
subclass of: SO_0000673
so part of: YPL112C
location: complement(337436..338620)
location: region:337436-338620:-1
so has part: feature:337436-338620:-1:exon

NP_015213.1
type: Protein
SIO_000068: ncbiprotein

S000006033
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:337436-338620:-1:exon

YNCP0006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IMT2
locus tag: YNCP0006C
so part of: sequence
location: complement(338848..338919)
location: region:338848-338919:-1
so has part: feature:338848-338919:-1:exon
subclass of: SO_0000663

855992
type: Gene
SIO_000068: ncbigene

position:338848:-1
position: 338848
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:338919:-1
position: 338919
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:338848-338919:-1:exon

YNCP0006C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: IMT2
locus tag: YNCP0006C
product: tRNA-Met
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006413 translational initiation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0016282 eukaryotic 43S preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0071074 eukaryotic initiation factor eIF2 binding [PMID:14698289]
note: Methionine initiator tRNA (tRNA-Met); predicted by tRNAscan-SE analysis; one of four initiator methionine tRNAs in yeast that are functional for translation
SIO_010081: YNCP0006C
subclass of: SO_0000673
so part of: YNCP0006C
location: complement(338848..338919)
location: region:338848-338919:-1
so has part: feature:338848-338919:-1:exon

S000006667
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:338848-338919:-1:exon

YPL111W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPH15
gene: CAR1
locus tag: YPL111W
gene synonym: LPH15
so part of: sequence
location: <339944..>340945
location: region:339944-340945:1
so has part: feature:339944-340945:1:exon
subclass of: SO_0000010

855993
type: Gene
SIO_000068: ncbigene

position:339944:1
position: 339944
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:340945:1
position: 340945
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:339944-340945:1:exon

YPL111W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPH15
gene: CAR1
locus tag: YPL111W
gene synonym: LPH15
product: arginase
transcript id: NM_001183925.1
SIO_010081: YPL111W
subclass of: SO_0000673
so part of: YPL111W
location: <339944..>340945
location: region:339944-340945:1
so has part: feature:339944-340945:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:339944-340945:1:exon

YPL111W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPH15
gene: CAR1
locus tag: YPL111W
gene synonym: LPH15
EC number: 3.5.3.1
experiment: EXISTENCE:direct assay:GO:0004053 arginase activity [PMID:2404017]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:205532]
experiment: EXISTENCE:direct assay:GO:0008270 zinc ion binding [PMID:1939179]
experiment: EXISTENCE:direct assay:GO:0019547 arginine catabolic process to ornithine [PMID:2404017]
experiment: EXISTENCE:direct assay:GO:0030145 manganese ion binding [PMID:1939179]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0090368 regulation of ornithine metabolic process [PMID:12679340]
experiment: EXISTENCE:direct assay:GO:0090369 ornithine carbamoyltransferase inhibitor activity [PMID:12679340]
experiment: EXISTENCE:mutant phenotype:GO:0004053 arginase activity [PMID:14582193]
experiment: EXISTENCE:mutant phenotype:GO:0019547 arginine catabolic process to ornithine [PMID:14582193]
experiment: EXISTENCE:mutant phenotype:GO:0090368 regulation of ornithine metabolic process [PMID:12679340]
experiment: EXISTENCE:mutant phenotype:GO:0090369 ornithine carbamoyltransferase inhibitor activity [PMID:12679340]
note: Arginase, catabolizes arginine to ornithine and urea; expression responds to both induction by arginine and nitrogen catabolite repression; disruption decreases production of carcinogen ethyl carbamate during wine fermentation and also enhances freeze tolerance
codon start: 1
product: arginase
translation: METGPHYNYYKNRELSIVLAPFSGGQGKLGVEKGPKYMLKHGLQTSIEDLGWSTELEPSMDEAQFVGKLKMEKDSTTGGSSVMIDGVKAKRADLVGEATKLVYNSVSKVVQANRFPLTLGGDHSIAIGTVSAVLDKYPDAGLLWIDAHADINTIESTPSGNLHGCPVSFLMGLNKDVPHCPESLKWVPGNLSPKKIAYIGLRDVDAGEKKILKDLGIAAFSMYHVDKYGINAVIEMAMKAVHPETNGEGPIMCSYDVDGVDPLYIPATGTPVRGGLTLREGLFLVERLAESGNLIALDVVECNPDLAIHDIHVSNTISAGCAIARCALGETLL
SIO_010081: YPL111W
subclass of: SO_0000673
so part of: YPL111W
location: 339944..340945
location: region:339944-340945:1
so has part: feature:339944-340945:1:exon

NP_015214.1
type: Protein
SIO_000068: ncbiprotein

S000006032
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:339944-340945:1:exon

YPL110C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GDE1
locus tag: YPL110C
so part of: sequence
location: complement(<341068..>344739)
location: region:341068-344739:-1
so has part: feature:341068-344739:-1:exon
subclass of: SO_0000010

855994
type: Gene
SIO_000068: ncbigene

position:341068:-1
position: 341068
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:344739:-1
position: 344739
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:341068-344739:-1:exon

YPL110C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GDE1
locus tag: YPL110C
product: glycerophosphocholine phosphodiesterase
transcript id: NM_001183924.1
SIO_010081: YPL110C
subclass of: SO_0000673
so part of: YPL110C
location: complement(<341068..>344739)
location: region:341068-344739:-1
so has part: feature:341068-344739:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:341068-344739:-1:exon

YPL110C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GDE1
locus tag: YPL110C
EC number: 3.1.4.2
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0046475 glycerophospholipid catabolic process [PMID:16141200]
experiment: EXISTENCE:mutant phenotype:GO:0047389 glycerophosphocholine phosphodiesterase activity [PMID:16141200]
note: Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes
codon start: 1
product: glycerophosphocholine phosphodiesterase
translation: MKFGKTFANHRIPEWSSQYVGYKSLKKMIKEITRLQEDIYRAHNKNSYDEGRPPTKMRDSSNSAQNYLDSPKIQKLLASFFFAVDRDIEKVDTFYNSQYAEYKKRFERLLSSNQFNEIKSTLVVDANKEDAVAQTLLTKDTREMNMLLKGTSQASRLSYHKDDLIEIQSILAELRKQFRNLKWYAELNKRAFGKILKKLDKKVGTNQQMSTMKTRILPLQFANDSLITKDLSLLKTIWEQVTFRINSYERVMRSTSPNANANDNTEFFKIICVFIEEDDSKGLIRELTNLYSELSLIPTRIMISVLNKAALSKSLACIDAILKVIPSLNDSEDINRRNFFHHHIIAIGKLIRKQEILSRKKKSQPSKYTNSEGEIVTDLRTLHTTLSAPAESDSITEEEKSSACTLSYILEELPIHLRPCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMVQIRDELVTHPHSQLNSGSEEKEPLNEISAGELNERNENGNGGNKGSLGKLAGPIKSYGHRFLDNNESLILITLGSNDTRNKSPSISLSSEALAKVIGLETDCALSLVISCNDSIDKSSVILDLPLDDNVDAVDFKVPFKVDYSHTLYFDIVPTYGTRSLETHNRIDCQKNNNNYVMARGVSMLNKSYSSVGVNRSILNGSVTVPIIANHTLEILGTLKFEYIIITPFEHPQLPLERTETYWKSLVSTRVIGHRGLGKNNPNKSLQIGENTVESFIMAASLGASYVEFDVQLTKDNVPVVYHDFLVAETGVDIPMHELTLEQFLDLNNADKEHIQRGAGHSPHHVNGADTALQKYRGRSVDDSDVSTLRRAWDLHDNDPNGKSNNAHWSDNRMRLTKTFKKNNFKGNARGHSIASSFVTLKELFKKIPANVGFNIECKFPMLDEAEEEELGQIMMEMNHWVDTVLKVVFDNANGRDIIFSSFHPDICIMLSLKQPVIPILFLTEGGSEQMADLRASSLQNGIRFAKKWNLLGIVSAAAPILKAPRLVQVVKSNGLVCVTYGVDNNDPENASIQIEAGVDAVIVDSVLAIRRGLTKKNEK
SIO_010081: YPL110C
subclass of: SO_0000673
so part of: YPL110C
location: complement(341068..344739)
location: region:341068-344739:-1
so has part: feature:341068-344739:-1:exon

NP_015215.1
type: Protein
SIO_000068: ncbiprotein

S000006031
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:341068-344739:-1:exon

YPL109C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MCO76
gene: CQD1
locus tag: YPL109C
gene synonym: MCO76
so part of: sequence
location: complement(<345264..>347389)
location: region:345264-347389:-1
so has part: feature:345264-347389:-1:exon
subclass of: SO_0000010

855995
type: Gene
SIO_000068: ncbigene

position:345264:-1
position: 345264
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:347389:-1
position: 347389
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:345264-347389:-1:exon

YPL109C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MCO76
gene: CQD1
locus tag: YPL109C
gene synonym: MCO76
product: Cqd1p
transcript id: NM_001183923.1
SIO_010081: YPL109C
subclass of: SO_0000673
so part of: YPL109C
location: complement(join(<345264..345444,345597..>347389))
location: region:345264-347389:-1
so has part: feature:345597-347389:-1:exon
so has part: feature:345264-345444:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:345597-347389:-1:exon

position:345597:-1
position: 345597
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:345264-345444:-1:exon

position:345444:-1
position: 345444
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL109C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MCO76
gene: CQD1
locus tag: YPL109C
gene synonym: MCO76
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961]
note: UbiB family mitochondrial protein; involved in mobilization of CoQ from its site of synthesis on the inner mitochondrial membrane to other sites of action; contains transmembrane domain and mitochondrial targeting sequence
codon start: 1
product: Cqd1p
translation: MSFLKFAYRNSWRYYSKSTRHFHKIPIRQFIIPTSIAFYLTQNSFPKQNCLIYNDSLKPDPKGDTFEMGLYVSSENELQEKLKSFRSAKITESRNKLIRYLRIFWFGFNDNIVEPVCTILRFLEISAIFLPLLLLYPISWFGHKLKITDTNITETRGSLIWCQLLRKALELAGPSFIKLGQWAGSRTDIFSHALCHELGKLHSNVTAHSLSFTLEKLSQALKVDKIEDAFDEFNRTPIGVGSIAQVYVGELSQKYIDKYDNIQIGKDGNRWCAIKILHPNVRSQIRRDLKIMKFCADAINWIPTMEWLSLPSEVDQFSILMNIQLDLRIEALNLERFNENFKNSIQVKFPKPFLPLSNRDVMFEEHVYGLSMEKFLSTKKQINDVELCKKVSDPFVDAFLQMLILDDFVHADLHPGNVIIRFVKTNKYGTNIISSELESYRITHDLRKKIEEDQDQDFVGKLKSVLTNYTPQICFIDTGIITELNEKNRINFIALFNALARFDGYRAGELMIERSRTPETAIDKEVFAFKVEKLVDKVKQRTFTLGTVSIGDLLDQMLSMVRSHHVRMESDFVSVVVAILLLEGIGRQLDPNLDLFESSLPILREFGFKREAKSLLKDASTLSMLKIWVGLEVRQLMHLSMKQIYDLVRTDQLCPNY
SIO_010081: YPL109C
subclass of: SO_0000673
so part of: YPL109C
location: complement(join(345264..345444,345597..347389))
location: region:345264-347389:-1
so has part: feature:345597-347389:-1:exon
so has part: feature:345264-345444:-1:exon

NP_015216.3
type: Protein
SIO_000068: ncbiprotein

S000006030
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:345597-347389:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:345264-345444:-1:exon

YPL108W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL108W
so part of: sequence
location: <348446..>348952
location: region:348446-348952:1
so has part: feature:348446-348952:1:exon
subclass of: SO_0000010

855996
type: Gene
SIO_000068: ncbigene

position:348446:1
position: 348446
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:348952:1
position: 348952
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:348446-348952:1:exon

YPL108W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL108W
product: uncharacterized protein
transcript id: NM_001183922.1
SIO_010081: YPL108W
subclass of: SO_0000673
so part of: YPL108W
location: <348446..>348952
location: region:348446-348952:1
so has part: feature:348446-348952:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:348446-348952:1:exon

YPL108W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL108W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic hypothetical protein; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
codon start: 1
product: uncharacterized protein
translation: MKEASDREEAPKMVEKNYSTGFRKAHGEKDQSVTKPISLDGRTGEVIVRKSTGKTKIRKGQTEEEYTQQLQHYFEVEQGPVRTKVGWMDEVDPLVEIREGKYDISNKHQRQVLSGFCHRLFYQCKYKECLDLSTYFLGLFEPFNVKNKMKRELEELEYMIERCRGHVL
SIO_010081: YPL108W
subclass of: SO_0000673
so part of: YPL108W
location: 348446..348952
location: region:348446-348952:1
so has part: feature:348446-348952:1:exon

NP_015217.1
type: Protein
SIO_000068: ncbiprotein

S000006029
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:348446-348952:1:exon

YPL107W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DPC25
locus tag: YPL107W
so part of: sequence
location: <349119..>349865
location: region:349119-349865:1
so has part: feature:349119-349865:1:exon
subclass of: SO_0000010

855997
type: Gene
SIO_000068: ncbigene

position:349119:1
position: 349119
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:349865:1
position: 349865
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:349119-349865:1:exon

YPL107W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DPC25
locus tag: YPL107W
product: Dpc25p
transcript id: NM_001183921.1
SIO_010081: YPL107W
subclass of: SO_0000673
so part of: YPL107W
location: <349119..>349865
location: region:349119-349865:1
so has part: feature:349119-349865:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:349119-349865:1:exon

YPL107W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DPC25
locus tag: YPL107W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
note: Putative mitochondrial hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; DPC25 is not an essential gene
codon start: 1
product: Dpc25p
translation: MIRNQGWSLLYRIYPVRRFTRYSRVDMTFEGNTQDISTSVEERMTTVFGGRLKGEPPRSTSRVLSGGTKKIAGVQVPAKPQEPDNCCMSGCVNCVWEIYSEDLRDWKHRRKEAAEKIAGTKEKWPKDWNPPLGLLHMENVPVELREKKLETDSKKAEQPHDLSAIRSLFPKRKGPLPKSVLAAKRKNIALRHNYEQKDGGDQSVSESDADEGWEDIPVYVKAFAEFESKKRLQKIRRQEEIKKRTALV
SIO_010081: YPL107W
subclass of: SO_0000673
so part of: YPL107W
location: 349119..349865
location: region:349119-349865:1
so has part: feature:349119-349865:1:exon

NP_015218.1
type: Protein
SIO_000068: ncbiprotein

S000006028
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:349119-349865:1:exon

YPL106C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG3
alternative label: MSI3
gene: SSE1
locus tag: YPL106C
gene synonym: LPG3; MSI3
so part of: sequence
location: complement(<350194..>352275)
location: region:350194-352275:-1
so has part: feature:350194-352275:-1:exon
subclass of: SO_0000010

855998
type: Gene
SIO_000068: ncbigene

position:350194:-1
position: 350194
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:352275:-1
position: 352275
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:350194-352275:-1:exon

YPL106C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG3
alternative label: MSI3
gene: SSE1
locus tag: YPL106C
gene synonym: LPG3; MSI3
product: adenyl-nucleotide exchange factor SSE1
transcript id: NM_001183920.1
SIO_010081: YPL106C
subclass of: SO_0000673
so part of: YPL106C
location: complement(<350194..>352275)
location: region:350194-352275:-1
so has part: feature:350194-352275:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:350194-352275:-1:exon

YPL106C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG3
alternative label: MSI3
gene: SSE1
locus tag: YPL106C
gene synonym: LPG3; MSI3
experiment: EXISTENCE:direct assay:GO:0000774 adenyl-nucleotide exchange factor activity [PMID:17154545|PMID:16688212]
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:17154545|PMID:15028727]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:16413483]
experiment: EXISTENCE:direct assay:GO:0042026 protein refolding [PMID:16688212]
experiment: EXISTENCE:direct assay:GO:0042277 peptide binding [PMID:18539149]
experiment: EXISTENCE:genetic interaction:GO:0010499 proteasomal ubiquitin-independent protein catabolic process [PMID:29507114]
experiment: EXISTENCE:genetic interaction:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:29507114]
experiment: EXISTENCE:mutant phenotype:GO:0005524 ATP binding [PMID:15028727]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:10480867]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:31962153]
note: ATPase component of heat shock protein Hsp90 chaperone complex; serves as nucleotide exchange factor to load ATP onto the SSA class of cytosolic Hsp70s; plays a role in prion propagation and determining prion variants; binds unfolded proteins; member of Hsp110 subclass of HSP70 proteins; deletion results in spindle elongation in S phase; SSE1 has a paralog, SSE2, that arose from the whole genome duplication
codon start: 1
product: adenyl-nucleotide exchange factor SSE1
translation: MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAFGKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEEAYTIEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEELASLGNIIRGRYLAKEEEKKQAIRSKQEASQMAAMAEKLAAQRKAEAEKKEEKKDTEGDVDMD
SIO_010081: YPL106C
subclass of: SO_0000673
so part of: YPL106C
location: complement(350194..352275)
location: region:350194-352275:-1
so has part: feature:350194-352275:-1:exon

NP_015219.1
type: Protein
SIO_000068: ncbiprotein

S000006027
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:350194-352275:-1:exon

YPL105C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MYR1
gene: SYH1
locus tag: YPL105C
gene synonym: MYR1
so part of: sequence
location: complement(<352863..>355412)
location: region:352863-355412:-1
so has part: feature:352863-355412:-1:exon
subclass of: SO_0000010

855999
type: Gene
SIO_000068: ncbigene

position:352863:-1
position: 352863
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:355412:-1
position: 355412
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:352863-355412:-1:exon

YPL105C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MYR1
gene: SYH1
locus tag: YPL105C
gene synonym: MYR1
product: Syh1p
transcript id: NM_001183919.1
SIO_010081: YPL105C
subclass of: SO_0000673
so part of: YPL105C
location: complement(<352863..>355412)
location: region:352863-355412:-1
so has part: feature:352863-355412:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:352863-355412:-1:exon

YPL105C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MYR1
gene: SYH1
locus tag: YPL105C
gene synonym: MYR1
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:17804396]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18327588|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:genetic interaction:GO:0051664 nuclear pore localization [PMID:18327588]
note: hypothetical protein that influences nuclear pore distribution; co-purifies with ribosomes; contains a GYF domain, which bind proline-rich sequences; deletion extends chronological lifespan; SYH1 has a paralog, SMY2, that arose from the whole genome duplication
codon start: 1
product: Syh1p
translation: MNPINSLAFDLHSVKLADANSDTAALSNSNTPTMNNAALLQRPSSIMDSIGVQRVPSPFVPGSNAISGASTVPFNAYDAEITGSPLQISANQENNSAFSAASSNLHMNASSPSVLNKPSSTFPNVAPYLYNATGPAPNVGNQPPPPGIESQWKYIDSNGNIQGPFGTNNMSQWYQGGYFTPTLQICRLATSPEPFGVNDRFIRLGELTTLVNNYQDPFVAFDFIVIRALNAVPLVAPTSSEKQKVESRDLIPVADVHSDDFTYEEILGLKFEDGSYYHETQVWVPVDGRHITKVDRIPKISAYTAPLSTTSSRSNKTTSSHEEKVPSHEEASPEEQEVFSEEGRTVSNITNEEESIVKNPTKQEEESRGSEKEQNILDQVQPEIEEVDRKDVISTADEPKSKDTPQMTSEEQKRFAKAELMAQKLLEEQQRQEEEKKRREEQRKLKKEKKLKQKQKKEEEKLKKKKKEEGKLEKEKQKELLNNILTGDTETPSSENTATSITTNLAPWANKKPEGAVYNQISSALEDLKKENSSKKEKKPNRTQLDREQALKLQKEILSSAQIPKTQTGSAWGIKPQQPIKVDIKGELMKDSTKINSQSKINKANNGDIKPDSTFIEEQKKLWEQVQKKTKKFNRASSLDDFISRTPSPSSSALNSSNTSNAWTTVSSKSTTHIASTMPVAGNQSKSYISLDTLRSSGGLSTATKTKMSDKSKQIGSSTSIPTLKARQVKPSRIPAYPGNASVSKRQEFLRWCRSQLKLNTGVQPDNVLEMLLSLPPGSESKEIIADTIYSYSSTMDGRRFATDFIKKRLECEEEINDPLSWSEVLAMPEGSSEDWEFQVVGKKKGKRF
SIO_010081: YPL105C
subclass of: SO_0000673
so part of: YPL105C
location: complement(352863..355412)
location: region:352863-355412:-1
so has part: feature:352863-355412:-1:exon

NP_015220.1
type: Protein
SIO_000068: ncbiprotein

S000006026
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:352863-355412:-1:exon

YPL104W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG5
gene: MSD1
locus tag: YPL104W
gene synonym: LPG5
so part of: sequence
location: <355700..>357676
location: region:355700-357676:1
so has part: feature:355700-357676:1:exon
subclass of: SO_0000010

856000
type: Gene
SIO_000068: ncbigene

position:355700:1
position: 355700
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:357676:1
position: 357676
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355700-357676:1:exon

YPL104W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG5
gene: MSD1
locus tag: YPL104W
gene synonym: LPG5
product: aspartate--tRNA ligase MSD1
transcript id: NM_001183918.1
SIO_010081: YPL104W
subclass of: SO_0000673
so part of: YPL104W
location: <355700..>357676
location: region:355700-357676:1
so has part: feature:355700-357676:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:355700-357676:1:exon

YPL104W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG5
gene: MSD1
locus tag: YPL104W
gene synonym: LPG5
EC number: 6.1.1.12
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0070146 mitochondrial aspartyl-tRNA aminoacylation [PMID:10710420]
experiment: EXISTENCE:mutant phenotype:GO:0004815 aspartate-tRNA ligase activity [PMID:2668951]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:2668951]
experiment: EXISTENCE:mutant phenotype:GO:0070146 mitochondrial aspartyl-tRNA aminoacylation [PMID:2668951]
note: Mitochondrial aspartyl-tRNA synthetase; required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene
codon start: 1
product: aspartate--tRNA ligase MSD1
translation: MLARSRVCLQTITRRLADFPEANAIKKKFLFRKDTSTIKQLKGLSSGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDNKSLLKGFTLEDVVQAVGILSLKRKLSNEDADEYEVQLEDITVLNASNKKPAQMQDFKLSAIYPPEFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNFDFTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQVDMEMAFANSEDVMKIIEKTVSGVWSKFSKKRGLLTLDSKGTLVPAKKENGTVSIFRMTYEQAMTSYGIDKPDLRAPDLKIINLGEFNAFSHLNKKFPVFEVIILRSAFSNMEEYKERWSFLTNNSNYNYRVPIVLPIENDEQANSNWFENFHAIATFENPHLITKFLKLKKGDIVCGCTREPNHSIFENPTPLGRLRQLVLQSEHGKNIYHAVNKDVASWIVDFPLFSPVIIEDKSGKKEKLAYPEYEKDRLCSTHHPFTMVKLKDYEKLEKTPEKCLGRHYDLVVNGVELGGGSTRIHDPRLQDYIFEDILKIDNAYELFGHLLNAFDMGTPPHAGFAIGFDRMCAMICETESIRDVIAFPKSITGADLVVKSPSVIPESILEPYNIKYSNSKK
SIO_010081: YPL104W
subclass of: SO_0000673
so part of: YPL104W
location: 355700..357676
location: region:355700-357676:1
so has part: feature:355700-357676:1:exon

NP_015221.1
type: Protein
SIO_000068: ncbiprotein

S000006025
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:355700-357676:1:exon

YPL103C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMP30
locus tag: YPL103C
so part of: sequence
location: complement(<358000..>359406)
location: region:358000-359406:-1
so has part: feature:358000-359406:-1:exon
subclass of: SO_0000010

856001
type: Gene
SIO_000068: ncbigene

position:358000:-1
position: 358000
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:359406:-1
position: 359406
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:358000-359406:-1:exon

YPL103C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMP30
locus tag: YPL103C
product: N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D
transcript id: NM_001183917.1
SIO_010081: YPL103C
subclass of: SO_0000673
so part of: YPL103C
location: complement(<358000..>359406)
location: region:358000-359406:-1
so has part: feature:358000-359406:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:358000-359406:-1:exon

YPL103C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMP30
locus tag: YPL103C
EC number: 3.1.4.54
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:21306442]
experiment: EXISTENCE:mutant phenotype:GO:0070291 N-acylethanolamine metabolic process [PMID:15878693]
experiment: EXISTENCE:mutant phenotype:GO:0070292 N-acylphosphatidylethanolamine metabolic process [PMID:15878693]
note: Protein with a role in maintaining mitochondrial morphology; also involved in maintaining normal cardiolipin levels; mitochondrial inner membrane protein; proposed to be involved in N-acylethanolamine metabolism; related to mammalian N-acylPE-specific phospholipase D
codon start: 1
product: N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D
translation: MNFVTCHVQMRLLLQRRLVRLRESELFRPQTSLSTFKRHASQKTRPIQKCSRKYARILLLSVLVPYTGYAFYVSLATVKQIDLRNEMCQRLEENNNEVTYKGSLLKYSPLEVLGRFENPFEEYRIQTVFEFFANRVFELFERNRGGIPRDVHQMNKLMPVHKPTWGPNLVDVDPAEETALPLECKVLDELHIPTAVEENEGSKCPVYNTWLGQSCNYTVYNGLRILTDPLFSDFLIHKTLGPKRITQMPSQITEVPKPDIILVSHNHPDHLDLESLEYWSGKDSPLWIVPKGMKSYMTSNGCDNVLELSWWETLQVKKNNEIYHISATPAMHWSGRSLLDTNKSLWCSFLLTHHGNPILFHAGDTGYVKDLFVRIKERFGKGCKLALLPCGQYCPEWHQKPRHINPQEVLKIMKDLEARNVLGVHWGTFVLSGEYFLEPKEKLEMLAEWGGFKDRCYCPELGKTECFD
SIO_010081: YPL103C
subclass of: SO_0000673
so part of: YPL103C
location: complement(358000..359406)
location: region:358000-359406:-1
so has part: feature:358000-359406:-1:exon

NP_015222.1
type: Protein
SIO_000068: ncbiprotein

S000006024
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:358000-359406:-1:exon

YPL101W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HAP1
alternative label: KTI9
alternative label: TOT7
gene: ELP4
locus tag: YPL101W
gene synonym: HAP1; KTI9; TOT7
so part of: sequence
location: <360209..>361579
location: region:360209-361579:1
so has part: feature:360209-361579:1:exon
subclass of: SO_0000010

856002
type: Gene
SIO_000068: ncbigene

position:360209:1
position: 360209
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:361579:1
position: 361579
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:360209-361579:1:exon

YPL101W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HAP1
alternative label: KTI9
alternative label: TOT7
gene: ELP4
locus tag: YPL101W
gene synonym: HAP1; KTI9; TOT7
product: Elongator subunit ELP4
transcript id: NM_001183915.1
SIO_010081: YPL101W
subclass of: SO_0000673
so part of: YPL101W
location: <360209..>361579
location: region:360209-361579:1
so has part: feature:360209-361579:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:360209-361579:1:exon

YPL101W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HAP1
alternative label: KTI9
alternative label: TOT7
gene: ELP4
locus tag: YPL101W
gene synonym: HAP1; KTI9; TOT7
experiment: EXISTENCE:direct assay:GO:0000049 tRNA binding [PMID:22343726]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:22343726]
experiment: EXISTENCE:direct assay:GO:0033588 elongator holoenzyme complex [PMID:11689709]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:11689709]
note: Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity; null mutation is functionally complemented by human ELP4
codon start: 1
product: Elongator subunit ELP4
translation: MSFRKRGEILNDRGSGLRGPLLRGPPRTSSTPLRTGNRRAPGNVPLSDTTARLKKLNIADESKTKMGLDSSHVGVRPSPATSQPTTSTGSADLDSILGHMGLPLGNSVLVEEQSTTEFHSILGKLFAAQGIVHNRISDSSADKTRNGDTHVIVLSLNQMFAKELPGIYKGSRKQMKKNLISEEESKVTVQNLNETQRSTPSRYKDLKIAWKYKLADEKRLGSPDRDDIQQNSEYKDYNHQFDITTRLMPAPIASELTFIAPTQPVSTILSQIEQTIKRNDKKLIRIVIPSLLHPAMYPPKMFESSEIIGLMHGVRSLVKKYYERVVLFASISIDIITPPLLVLLRNMFDSVINLEPFNQEMTEFLERVYKSQPGKIQHGLVHILKLPVFTDRGEMRVLKSEWAFKNGRKKFEIEQWGIPVDDAEGSAASEQSHSHSHSDEISHNIPAKKTKISLDY
SIO_010081: YPL101W
subclass of: SO_0000673
so part of: YPL101W
location: 360209..361579
location: region:360209-361579:1
so has part: feature:360209-361579:1:exon

NP_015224.1
type: Protein
SIO_000068: ncbiprotein

S000006022
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:360209-361579:1:exon

YPL100W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HSV1
alternative label: MAI1
gene: ATG21
locus tag: YPL100W
gene synonym: HSV1; MAI1
so part of: sequence
location: <361872..>363362
location: region:361872-363362:1
so has part: feature:361872-363362:1:exon
subclass of: SO_0000010

856004
type: Gene
SIO_000068: ncbigene

position:361872:1
position: 361872
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:363362:1
position: 363362
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:361872-363362:1:exon

YPL100W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HSV1
alternative label: MAI1
gene: ATG21
locus tag: YPL100W
gene synonym: HSV1; MAI1
product: Atg21p
transcript id: NM_001183914.1
SIO_010081: YPL100W
subclass of: SO_0000673
so part of: YPL100W
location: <361872..>363362
location: region:361872-363362:1
so has part: feature:361872-363362:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:361872-363362:1:exon

YPL100W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HSV1
alternative label: MAI1
gene: ATG21
locus tag: YPL100W
gene synonym: HSV1; MAI1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:11852075|PMID:15194695|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:25691244]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:18769150]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11852075]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:15155809|PMID:16876790]
experiment: EXISTENCE:direct assay:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:15155809]
experiment: EXISTENCE:direct assay:GO:0080025 phosphatidylinositol-3,5-bisphosphate binding [PMID:15103325]
experiment: EXISTENCE:mutant phenotype:GO:0000407 phagophore assembly site [PMID:25691244]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0006497 protein lipidation [PMID:15155809]
experiment: EXISTENCE:mutant phenotype:GO:0016050 vesicle organization [PMID:15155809]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:15194695]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:16876790]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:15155809|PMID:25691244]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
note: Phosphoinositide binding protein; required for vesicle formation in cytoplasm-to-vacuole targeting (CVT) pathway, autophagy, micronucleophagy and mitophagy; binds to several phosphoinositides including PtdIns(3,5)P2, PI3P and PI4P; involved in PI3P-dependent recruitment and organization of both Atg12-Atg5-Atg16 complex and Atg8p at pre-autophagosomal structure; necessary for oxidant-induced cell death; targeted to vacuole via AP-3 pathway; WD-40 repeat containing PROPPIN family member
codon start: 1
product: Atg21p
translation: MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRGQGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGDSANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKKIKSSIPNQNLSRNFAYITVNESNRSCLGFPDEFPNQVYIASDDGTFSIYSIPSKPGECVLTKNNKFT
SIO_010081: YPL100W
subclass of: SO_0000673
so part of: YPL100W
location: 361872..363362
location: region:361872-363362:1
so has part: feature:361872-363362:1:exon

NP_015225.1
type: Protein
SIO_000068: ncbiprotein

S000006021
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:361872-363362:1:exon

YPL099C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AIM43
alternative label: FMP14
gene: INA17
locus tag: YPL099C
gene synonym: AIM43; FMP14
so part of: sequence
location: complement(<363520..>364068)
location: region:363520-364068:-1
so has part: feature:363520-364068:-1:exon
subclass of: SO_0000010

856005
type: Gene
SIO_000068: ncbigene

position:363520:-1
position: 363520
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:364068:-1
position: 364068
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:363520-364068:-1:exon

YPL099C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AIM43
alternative label: FMP14
gene: INA17
locus tag: YPL099C
gene synonym: AIM43; FMP14
product: Ina17p
transcript id: NM_001183913.1
SIO_010081: YPL099C
subclass of: SO_0000673
so part of: YPL099C
location: complement(<363520..>364068)
location: region:363520-364068:-1
so has part: feature:363520-364068:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:363520-364068:-1:exon

YPL099C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AIM43
alternative label: FMP14
gene: INA17
locus tag: YPL099C
gene synonym: AIM43; FMP14
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:24942160]
experiment: EXISTENCE:direct assay:GO:1990524 INA complex [PMID:24942160]
experiment: EXISTENCE:genetic interaction:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:24942160]
experiment: EXISTENCE:mutant phenotype:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:24942160]
experiment: EXISTENCE:physical interaction:GO:1990524 INA complex [PMID:24942160]
note: F1F0 ATPase synthase peripheral stalk assembly factor; subunit of the matrix-exposed inner mitochondrial membrane localized INA complex (Ina22p-Ina17p) involved in assembly of the F1F0 peripheral stalk; co-purifies with Ina22p and ATP synthase subunits; null mutant displays elevated frequency of mitochondrial genome loss and has a respiratory growth defect
codon start: 1
product: Ina17p
translation: MLKRRSNALITLSRTKLFPITTVAYYHRRLLNQQRRAVSTSPKKEIKSLEDLANLDSLDGVDTELIRDLINEHTTKLNIKKELDMLKKFSQEEESGHEIPVKRFIRPLWMFILMGSSVYLLLHFSWWKLEHEERESQLKKEVEILEHQLNELIVQDKTHNTSRGKGSNESTHMKPWYRRWFW
SIO_010081: YPL099C
subclass of: SO_0000673
so part of: YPL099C
location: complement(363520..364068)
location: region:363520-364068:-1
so has part: feature:363520-364068:-1:exon

NP_015226.1
type: Protein
SIO_000068: ncbiprotein

S000006020
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:363520-364068:-1:exon

YPL098C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MGR2
locus tag: YPL098C
so part of: sequence
location: complement(<364386..>364727)
location: region:364386-364727:-1
so has part: feature:364386-364727:-1:exon
subclass of: SO_0000010

856006
type: Gene
SIO_000068: ncbigene

position:364386:-1
position: 364386
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:364727:-1
position: 364727
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:364386-364727:-1:exon

YPL098C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MGR2
locus tag: YPL098C
product: Mgr2p
transcript id: NM_001183912.1
SIO_010081: YPL098C
subclass of: SO_0000673
so part of: YPL098C
location: complement(<364386..>364727)
location: region:364386-364727:-1
so has part: feature:364386-364727:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:364386-364727:-1:exon

YPL098C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MGR2
locus tag: YPL098C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:22613836]
experiment: EXISTENCE:mutant phenotype:GO:0045039 protein insertion into mitochondrial inner membrane [PMID:25454944]
experiment: EXISTENCE:physical interaction:GO:0005744 TIM23 mitochondrial import inner membrane translocase complex [PMID:22613836]
note: Subunit of the TIM23 translocase complex; acts to couple Tim21p with the core Tim23 translocase; provides quality control for insertion of membrane proteins by regulating their release into the inner membrane by the TIM23 complex; absolutely required for mitochondrial import of presequence-containing proteins at elevated temperature; required for viability of cells lacking the mitochondrial genome (petite-negative phenotype)
codon start: 1
product: Mgr2p
translation: MPPLPQNYAQQQPSNWDKFKMGLMMGTTVGVCTGILFGGFAIATQGPGPDGVVRTLGKYIAGSAGTFGLFMSIGSIIRSDSESSPMSHPNLNLQQQARLEMWKLRAKYGIRKD
SIO_010081: YPL098C
subclass of: SO_0000673
so part of: YPL098C
location: complement(364386..364727)
location: region:364386-364727:-1
so has part: feature:364386-364727:-1:exon

NP_015227.1
type: Protein
SIO_000068: ncbiprotein

S000006019
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:364386-364727:-1:exon

YPL097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MSY1
locus tag: YPL097W
so part of: sequence
location: <364952..>366430
location: region:364952-366430:1
so has part: feature:364952-366430:1:exon
subclass of: SO_0000010

856007
type: Gene
SIO_000068: ncbigene

position:364952:1
position: 364952
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:366430:1
position: 366430
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:364952-366430:1:exon

YPL097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MSY1
locus tag: YPL097W
product: tyrosine--tRNA ligase MSY1
transcript id: NM_001183911.1
SIO_010081: YPL097W
subclass of: SO_0000673
so part of: YPL097W
location: <364952..>366430
location: region:364952-366430:1
so has part: feature:364952-366430:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:364952-366430:1:exon

YPL097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MSY1
locus tag: YPL097W
EC number: 6.1.1.1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0004831 tyrosine-tRNA ligase activity [PMID:3315228]
experiment: EXISTENCE:genetic interaction:GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation [PMID:3315228]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:3315228]
note: Mitochondrial tyrosyl-tRNA synthetase
codon start: 1
product: tyrosine--tRNA ligase MSY1
translation: MLELRSCSNLVNSSRRLVPLVTYSGLSAITLPKSRFYSQPSALEVQGTSDSRSDNILDELKQRGLVSQVSQPESFLRTKLNGNDKIKLYCGVDPTAQSLHLGNLVPLMVLLHFYVKGHDIVTVIGGATGKVGDPSGRKTERDVMENDIRQSNVASISQQLQRFFKNGLEYYRNRCALTEDVPSGKYTPRNNFNWWKDIKMLDFLADFGRHIRVQSMLARDSISSRLQTKNGLGFNEFTYQVLQAYDFYHLYKEENVTIQVGGNDQWGNITAGIDLINRIQPIKNKGLPFGITVPLLTTATGEKFGKSAGNAVFIDPSINTAYDVYQFFYNTLDADVPKFLKIFTFLNSSEIKKIVETHIKSPSLRYGQTLLAKEVTDMLYGVGSGSDSEALSNIIFGRYDGTLSAAKLVDLCKKARILQYADREIDLIKLICKLVNCSVSEARRKLSQGSVYLHHSKSKVNENISNLAPFLIDDRVLILRIGKQKCFIIEMR
SIO_010081: YPL097W
subclass of: SO_0000673
so part of: YPL097W
location: 364952..366430
location: region:364952-366430:1
so has part: feature:364952-366430:1:exon

NP_015228.1
type: Protein
SIO_000068: ncbiprotein

S000006018
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:364952-366430:1:exon

YPL096C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RIN1
gene: ERI1
locus tag: YPL096C-A
gene synonym: RIN1
so part of: sequence
location: complement(<366529..>366735)
location: region:366529-366735:-1
so has part: feature:366529-366735:-1:exon
subclass of: SO_0000010

856008
type: Gene
SIO_000068: ncbigene

position:366529:-1
position: 366529
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:366735:-1
position: 366735
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:366529-366735:-1:exon

YPL096C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RIN1
gene: ERI1
locus tag: YPL096C-A
gene synonym: RIN1
product: Eri1p
transcript id: NM_001184515.1
SIO_010081: YPL096C-A
subclass of: SO_0000673
so part of: YPL096C-A
location: complement(<366529..>366735)
location: region:366529-366735:-1
so has part: feature:366529-366735:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:366529-366735:-1:exon

YPL096C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RIN1
gene: ERI1
locus tag: YPL096C-A
gene synonym: RIN1
experiment: EXISTENCE:direct assay:GO:0005095 GTPase inhibitor activity [PMID:12832483]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:12832483]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:15163411]
experiment: EXISTENCE:mutant phenotype:GO:0007265 Ras protein signal transduction [PMID:12832483]
experiment: EXISTENCE:physical interaction:GO:0000506 glycosylphosphatidylinositol-N- acetylglucosaminyltransferase (GPI-GnT) complex [PMID:15163411]
note: Endoplasmic reticulum membrane protein that binds and inhibits Ras2p; binds to and inhibits GTP-bound Ras2p at the endoplasmic reticulum (ER); component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein
codon start: 1
product: Eri1p
translation: MRPRDQGFLVLGFTYSVLLISLATFYWLRNNDSFLHYWCVLLLCPATLWLWALIAWCDSEMFASSKDE
SIO_010081: YPL096C-A
subclass of: SO_0000673
so part of: YPL096C-A
location: complement(366529..366735)
location: region:366529-366735:-1
so has part: feature:366529-366735:-1:exon

NP_690846.1
type: Protein
SIO_000068: ncbiprotein

S000028423
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:366529-366735:-1:exon

YPL096W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PNG1
locus tag: YPL096W
so part of: sequence
location: <366927..>368018
location: region:366927-368018:1
so has part: feature:366927-368018:1:exon
subclass of: SO_0000010

856009
type: Gene
SIO_000068: ncbigene

position:366927:1
position: 366927
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:368018:1
position: 368018
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:366927-368018:1:exon

YPL096W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PNG1
locus tag: YPL096W
product: peptide-N4-(N-acetyl-beta- glucosaminyl)asparagine amidase
transcript id: NM_001183910.1
SIO_010081: YPL096W
subclass of: SO_0000673
so part of: YPL096W
location: <366927..>368018
location: region:366927-368018:1
so has part: feature:366927-368018:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:366927-368018:1:exon

YPL096W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PNG1
locus tag: YPL096W
EC number: 3.5.1.52
experiment: EXISTENCE:direct assay:GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [PMID:10831608]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10831608]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:10831608|PMID:15910746]
experiment: EXISTENCE:direct assay:GO:0006517 protein deglycosylation [PMID:10831608]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:10831608]
experiment: EXISTENCE:mutant phenotype:GO:0006517 protein deglycosylation [PMID:25497214|PMID:27433019]
experiment: EXISTENCE:mutant phenotype:GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway [PMID:27433019]
note: Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease
codon start: 1
product: peptide-N4-(N-acetyl-beta- glucosaminyl)asparagine amidase
translation: MGEVYEKNNIDFDSIAKMLLIKYKDFILSKFKKAAPVENIRFQNLVHTNQFAQGVLGQSQHLCTVYDNPSWHSIVLETLDLDLIYKNVDKEFAKDGHAEGENIYTDYLVKELLRYFKQDFFKWCNKPDCNHCGQNTSENMTPLGSQGPNGEESKFNCGTVEIYKCNRCGNITRFPRYNDPIKLLETRKGRCGEWCNLFTLILKSFGLDVRYVWNREDHVWCEYFSNFLNRWVHVDSCEQSFDQPYIYSINWNKKMSYCIAFGKDGVVDVSKRYILQNELPRDQIKEEDLKFLCQFITKRLRYSLNDDEIYQLACRDEQEQIELIRGKTQETKSESVSAASKSSNRGRESGSADWKAQRGEDGK
SIO_010081: YPL096W
subclass of: SO_0000673
so part of: YPL096W
location: 366927..368018
location: region:366927-368018:1
so has part: feature:366927-368018:1:exon

NP_015229.1
type: Protein
SIO_000068: ncbiprotein

S000006017
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:366927-368018:1:exon

YPL095C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EEB1
locus tag: YPL095C
so part of: sequence
location: complement(<368071..>369441)
location: region:368071-369441:-1
so has part: feature:368071-369441:-1:exon
subclass of: SO_0000010

856010
type: Gene
SIO_000068: ncbigene

position:368071:-1
position: 368071
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:369441:-1
position: 369441
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:368071-369441:-1:exon

YPL095C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EEB1
locus tag: YPL095C
product: medium-chain fatty acid ethyl ester synthase/esterase
transcript id: NM_001183909.1
SIO_010081: YPL095C
subclass of: SO_0000673
so part of: YPL095C
location: complement(<368071..>369441)
location: region:368071-369441:-1
so has part: feature:368071-369441:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:368071-369441:-1:exon

YPL095C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EEB1
locus tag: YPL095C
EC number: 2.3.1.84
experiment: EXISTENCE:direct assay:GO:0034321 alcohol O-octanoyltransferase activity [PMID:16361250]
experiment: EXISTENCE:direct assay:GO:0034338 short-chain carboxylesterase activity [PMID:16361250]
experiment: EXISTENCE:direct assay:GO:0051792 medium-chain fatty acid biosynthetic process [PMID:16361250]
experiment: EXISTENCE:mutant phenotype:GO:0051792 medium-chain fatty acid biosynthetic process [PMID:16361250]
experiment: EXISTENCE:mutant phenotype:GO:0051793 medium-chain fatty acid catabolic process [PMID:16361250]
note: Acyl-coenzymeA:ethanol O-acyltransferase; responsible for the major part of medium-chain fatty acid ethyl ester biosynthesis during fermentation; possesses short-chain esterase activity; may be involved in lipid metabolism and detoxification; EEB1 has a paralog, EHT1, that arose from the whole genome duplication
codon start: 1
product: medium-chain fatty acid ethyl ester synthase/esterase
translation: MFRSGYYPTVTPSHWGYNGTVKHVLGEKGTKSLAFRDSKRQIPLHEFVTKHVPTLKDGANFRLNSLLFTGYLQTLYLSAGDFSKKFQVFYGREIIKFSDGGVCTADWVMPEWEQTYSLNAEKASFNEKQFSNDEKATHPKGWPRLHPRTRYLSSEELEKCHSKGYSYPLVVVLHGLAGGSHEPLIRALSEDLSKVGDGKFQVVVLNARGCSRSKVTTRRIFTALHTGDVREFLNHQKALFPQRKIYAVGTSFGAAMLTNYLGEEGDNCPLNAAVALSNPWDFVHTWDKLAHDWWSNHIFSRTLTQFLTRTVKVNMNELQVPENFEVSHKPTVEKPVFYTYTRENLEKAEKFTDILEFDNLFTAPSMGLPDGLTYYRKASSINRLPNIKIPTLIINATDDPVTGENVIPYKQARENPCVLLCETDLGGHLAYLDNESNSWLTKQAAEFLGSFDELVL
SIO_010081: YPL095C
subclass of: SO_0000673
so part of: YPL095C
location: complement(368071..369441)
location: region:368071-369441:-1
so has part: feature:368071-369441:-1:exon

NP_015230.1
type: Protein
SIO_000068: ncbiprotein

S000006016
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:368071-369441:-1:exon

YPL094C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG14
gene: SEC62
locus tag: YPL094C
gene synonym: LPG14
so part of: sequence
location: complement(<369839..>370663)
location: region:369839-370663:-1
so has part: feature:369839-370663:-1:exon
subclass of: SO_0000010

856011
type: Gene
SIO_000068: ncbigene

position:369839:-1
position: 369839
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:370663:-1
position: 370663
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:369839-370663:-1:exon

YPL094C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG14
gene: SEC62
locus tag: YPL094C
gene synonym: LPG14
product: Sec63 complex subunit SEC62
transcript id: NM_001183908.1
SIO_010081: YPL094C
subclass of: SO_0000673
so part of: YPL094C
location: complement(<369839..>370663)
location: region:369839-370663:-1
so has part: feature:369839-370663:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:369839-370663:-1:exon

YPL094C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG14
gene: SEC62
locus tag: YPL094C
gene synonym: LPG14
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:27831485|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008320 protein transmembrane transporter activity [PMID:9252322]
experiment: EXISTENCE:direct assay:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:7758110]
experiment: EXISTENCE:physical interaction:GO:0031207 Sec62/Sec63 complex [PMID:2000150]
note: Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; cotranslationally N-acetylated by NatA; other members are Sec63p, Sec66p, and Sec72p
codon start: 1
product: Sec63 complex subunit SEC62
translation: MSAVGPGSNAGASVNGGSATAIATLLRNHKELKQRQGLFQAKQTDFFRYKRFVRALHSEEYANKSARQPEIYPTIPSNKIEDQLKSREIFIQLIKAQMVIPVKKLHSQECKEHGLKPSKDFPHLIVSNKAQLEADEYFVWNYNPRTYMDYLIVIGVVSIILALVCYPLWPRSMRRGSYYVSLGAFGILAGFFAVAILRLILYVLSLIVYKDVGGFWIFPNLFEDCGVLESFKPLYGFGEKDTYSYKKKLKRMKKKQAKRESNKKKAINEKAEQN
SIO_010081: YPL094C
subclass of: SO_0000673
so part of: YPL094C
location: complement(369839..370663)
location: region:369839-370663:-1
so has part: feature:369839-370663:-1:exon

NP_015231.2
type: Protein
SIO_000068: ncbiprotein

S000006015
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:369839-370663:-1:exon

YPL093W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NOG1
locus tag: YPL093W
so part of: sequence
location: <370978..>372921
location: region:370978-372921:1
so has part: feature:370978-372921:1:exon
subclass of: SO_0000010

856012
type: Gene
SIO_000068: ncbigene

position:370978:1
position: 370978
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:372921:1
position: 372921
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:370978-372921:1:exon

YPL093W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NOG1
locus tag: YPL093W
product: putative GTPase NOG1
transcript id: NM_001183907.1
SIO_010081: YPL093W
subclass of: SO_0000673
so part of: YPL093W
location: <370978..>372921
location: region:370978-372921:1
so has part: feature:370978-372921:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:370978-372921:1:exon

YPL093W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NOG1
locus tag: YPL093W
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11112701]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:31909713]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614|PMID:16861225|PMID:17443350|PMID:23212245]
experiment: EXISTENCE:direct assay:GO:0042273 ribosomal large subunit biogenesis [PMID:16888624]
experiment: EXISTENCE:mutant phenotype:GO:0000054 ribosomal subunit export from nucleus [PMID:12773575]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:12773575]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:17443350]
experiment: EXISTENCE:mutant phenotype:GO:1902626 assembly of large subunit precursor of preribosome [PMID:22735702|PMID:31909713]
note: Putative GTPase; associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
codon start: 1
product: putative GTPase NOG1
translation: MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKVKYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISRAKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYLEQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDEERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKLKSQSRINNVLNKIHVAQPQARDDVKRTPFIPESVKNLKKYDPEDPNRRKLARDIEAENGGAGVFNVNLKDKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENEGFYNSDDEEEIYDGFEASEVDDIKEKAAWIRNRQKTMIAEARNRKSLKNKAIMPRSKLTKSFGKMEEHMSTLGHDMSALQDKQNRAARKNRYVERGSDVVFGDQDALTASTENGVKLRQTDRLLDGVADGSMRSKADRMAKMERRERNRHAKQGESDRHNAVSLSKHLFSGKRGVGKTDFR
SIO_010081: YPL093W
subclass of: SO_0000673
so part of: YPL093W
location: 370978..372921
location: region:370978-372921:1
so has part: feature:370978-372921:1:exon

NP_015232.1
type: Protein
SIO_000068: ncbiprotein

S000006014
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:370978-372921:1:exon

YPL092W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG16
gene: SSU1
locus tag: YPL092W
gene synonym: LPG16
so part of: sequence
location: <373793..>375169
location: region:373793-375169:1
so has part: feature:373793-375169:1:exon
subclass of: SO_0000010

856013
type: Gene
SIO_000068: ncbigene

position:373793:1
position: 373793
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:375169:1
position: 375169
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:373793-375169:1:exon

YPL092W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG16
gene: SSU1
locus tag: YPL092W
gene synonym: LPG16
product: Ssu1p
transcript id: NM_001183906.1
SIO_010081: YPL092W
subclass of: SO_0000673
so part of: YPL092W
location: <373793..>375169
location: region:373793-375169:1
so has part: feature:373793-375169:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:373793-375169:1:exon

YPL092W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG16
gene: SSU1
locus tag: YPL092W
gene synonym: LPG16
experiment: EXISTENCE:direct assay:GO:0000316 sulfite transport [PMID:10870099]
experiment: EXISTENCE:direct assay:GO:0000319 sulfite transmembrane transporter activity [PMID:10870099]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:9294463]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Plasma membrane sulfite pump involved in sulfite metabolism; required for efficient sulfite efflux; major facilitator superfamily protein
codon start: 1
product: Ssu1p
translation: MVANWVLALTRQFDPFMFMMVMGVGISSNILYSFPYPARWLRICSYIMFAIACLIFIAVQALQILHLIVYIKEKSFREYFNDFFRNMKHNLFWGTYPMGLVTIINFLGALSKANTTKSPTNARNLMIFVYVLWWYDLAVCLVIAWGISFLIWHDYYPLEGIGNYPSYNIKMASENMKSVLLLDIIPLVVVASSCGTFTMSEIFFHAFNRNIQLITLVICALTWLHAIIFVFILIAIYFWSLYINKIPPMTQVFTLFLLLGPMGQGSFGVLLLTDNIKKYAGKYYPTDNITREQEILTIAVPWCFKILGMVSAMALLAMGYFFTVISVVSILSYYNKKEIENETGKVKRVYTFHKGFWGMTFPMGTMSLGNEELYVQYNQYVPLYAFRVLGTIYGGVCVCWSILCLLCTLHEYSKKMLHAARKSSLFSESGTEKTTVSPYNSIESVEESNSALDFTRLA
SIO_010081: YPL092W
subclass of: SO_0000673
so part of: YPL092W
location: 373793..375169
location: region:373793-375169:1
so has part: feature:373793-375169:1:exon

NP_015233.1
type: Protein
SIO_000068: ncbiprotein

S000006013
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:373793-375169:1:exon

YPL091W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG17
gene: GLR1
locus tag: YPL091W
gene synonym: LPG17
so part of: sequence
location: <375502..>376953
location: region:375502-376953:1
so has part: feature:375502-376953:1:exon
subclass of: SO_0000010

856014
type: Gene
SIO_000068: ncbigene

position:375502:1
position: 375502
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:376953:1
position: 376953
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:375502-376953:1:exon

YPL091W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG17
gene: GLR1
locus tag: YPL091W
gene synonym: LPG17
product: glutathione-disulfide reductase GLR1
transcript id: NM_001183905.1
SIO_010081: YPL091W
subclass of: SO_0000673
so part of: YPL091W
location: <375502..>376953
location: region:375502-376953:1
so has part: feature:375502-376953:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:375502-376953:1:exon

YPL091W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG17
gene: GLR1
locus tag: YPL091W
gene synonym: LPG17
EC number: 1.8.1.7
experiment: EXISTENCE:direct assay:GO:0004362 glutathione-disulfide reductase (NADPH) activity [PMID:19049979|PMID:7737505]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23613772|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:23613772]
experiment: EXISTENCE:genetic interaction:GO:0010731 protein glutathionylation [PMID:20074363]
experiment: EXISTENCE:mutant phenotype:GO:0006749 glutathione metabolic process [PMID:23242256]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:8951820]
experiment: EXISTENCE:mutant phenotype:GO:0045454 cell redox homeostasis [PMID:23242256]
note: Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; also detected in peroxisomes; protein abundance increases in response to DNA replication stress
codon start: 1
product: glutathione-disulfide reductase GLR1
translation: MLSATKQTFRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR
SIO_010081: YPL091W
subclass of: SO_0000673
so part of: YPL091W
location: 375502..376953
location: region:375502-376953:1
so has part: feature:375502-376953:1:exon

NP_015234.1
type: Protein
SIO_000068: ncbiprotein

S000006012
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:375502-376953:1:exon

YPL090C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPS6A
locus tag: YPL090C
so part of: sequence
location: complement(<377291..>378395)
location: region:377291-378395:-1
so has part: feature:377291-378395:-1:exon
subclass of: SO_0000010

856015
type: Gene
SIO_000068: ncbigene

position:377291:-1
position: 377291
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:378395:-1
position: 378395
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:377291-378395:-1:exon

YPL090C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPS6A
locus tag: YPL090C
product: ribosomal 40S subunit protein S6A
transcript id: NM_001183904.1
SIO_010081: YPL090C
subclass of: SO_0000673
so part of: YPL090C
location: complement(join(<377291..377995,378390..>378395))
location: region:377291-378395:-1
so has part: feature:378390-378395:-1:exon
so has part: feature:377291-377995:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:378390-378395:-1:exon

position:378390:-1
position: 378390
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:377291-377995:-1:exon

position:377995:-1
position: 377995
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL090C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPS6A
locus tag: YPL090C
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S6, no bacterial homolog; phosphorylated on S233 by Ypk3p in a TORC1-dependent manner, and on S232 in a TORC1/2-dependent manner by Ypk1/2/3p; RPS6A has a paralog, RPS6B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S6A
translation: MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
SIO_010081: YPL090C
subclass of: SO_0000673
so part of: YPL090C
location: complement(join(377291..377995,378390..378395))
location: region:377291-378395:-1
so has part: feature:378390-378395:-1:exon
so has part: feature:377291-377995:-1:exon

NP_015235.1
type: Protein
SIO_000068: ncbiprotein

S000006011
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:378390-378395:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:377291-377995:-1:exon

YPL089C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RLM1
locus tag: YPL089C
so part of: sequence
location: complement(<379120..>381150)
location: region:379120-381150:-1
so has part: feature:379120-381150:-1:exon
subclass of: SO_0000010

856016
type: Gene
SIO_000068: ncbigene

position:379120:-1
position: 379120
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:381150:-1
position: 381150
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:379120-381150:-1:exon

YPL089C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RLM1
locus tag: YPL089C
product: Rlm1p
transcript id: NM_001183903.1
SIO_010081: YPL089C
subclass of: SO_0000673
so part of: YPL089C
location: complement(<379120..>381150)
location: region:379120-381150:-1
so has part: feature:379120-381150:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:379120-381150:-1:exon

YPL089C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RLM1
locus tag: YPL089C
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9121433]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12410835]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:10064699]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:9121433]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9121433|PMID:12410835|PMID:15116342]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:7565726]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:20398213|PMID:12410835]
experiment: EXISTENCE:mutant phenotype:GO:0060256 regulation of flocculation [PMID:31441971]
experiment: EXISTENCE:mutant phenotype:GO:1903450 regulation of G1 to G0 transition [PMID:31141453]
note: MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication
codon start: 1
product: Rlm1p
translation: MGRRKIEIQRISDDRNRAVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEFSSVDTNDLIYHYQNDKNLLHEVKDPSDYGDFHKSASVNINQDLLRSSMSNKPSKSNVKGMNQSENDDDENNDEDDDDHGNFERNSNMHSNKKASDKNIPSAHMKLLSPTALISKMDGSEQNKRHPENALPPLQHLKRLKPDPLQISRTPQQQQQQNISRPYHSSMYNLNQPSSSSSSPSTMDFPKLPSFQNSSFNGRPPPISISPNKFSKPFTNASSRTPKQEHKINNSGSNNNDNSNYTQSPSNSLEDSIQQTVKARRKLSARPVLRVRIPNNNFSSNSAIPSEPSSASSTSANGNSMGSSQIMKENKTSRSSKISPLSASASGPLTLQKGNNGRMVIKLPNANAPNGSNNGNGSNNNNHPYPFGSGSSPLFSATQPYIATPLQPSNIPGGPFQQNTSFLAQRQTQQYQQMSFKKQSQTVPLTTTLTGRPPSTFSGPETSNGPPTGSLPSKFVHDLMSNSPNVSSISMFPDWSMGPNSAKPGNTNNPGTFPPVQTAVNNGNSSNISSTNNTNNNNNNNNNNSSNNNSNNGNDNNSNNSNNSYYSNNEDAPVNGAAISEHTTDGDSNNQSNSSTYDAAATAYNGNTGLTPYINTAQTPLGTKFFNFSTDISGEKNSSKI
SIO_010081: YPL089C
subclass of: SO_0000673
so part of: YPL089C
location: complement(379120..381150)
location: region:379120-381150:-1
so has part: feature:379120-381150:-1:exon

NP_015236.1
type: Protein
SIO_000068: ncbiprotein

S000006010
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:379120-381150:-1:exon

YPL088W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL088W
so part of: sequence
location: <381965..>382993
location: region:381965-382993:1
so has part: feature:381965-382993:1:exon
subclass of: SO_0000010

856017
type: Gene
SIO_000068: ncbigene

position:381965:1
position: 381965
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:382993:1
position: 382993
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:381965-382993:1:exon

YPL088W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL088W
product: aldo-keto reductase superfamily protein
transcript id: NM_001183902.1
SIO_010081: YPL088W
subclass of: SO_0000673
so part of: YPL088W
location: <381965..>382993
location: region:381965-382993:1
so has part: feature:381965-382993:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:381965-382993:1:exon

YPL088W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL088W
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:31945465]
note: Putative aryl alcohol dehydrogenase; localizes to cytosol; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
codon start: 1
product: aldo-keto reductase superfamily protein
translation: MVLVKQVRLGNSGLKISPIVIGCMSYGSKKWADWVIEDKTQIFKIMKHCYDKGLRTFDTADFYSNGLSERIIKEFLEYYSIKRETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQRGLSRKHIIAGVENSVKRLGTYIDLLQIHRLDHETPMKEIMKALNDVVEAGHVRYIGASSMLATEFAELQFTADKYGWFQFISSQSYYNLLYREDERELIPFAKRHNIGLLPWSPNARGMLTRPLNQSTDRIKSDPTFKSLHLDNLEEEQKEIINRVEKVSKDKKVSMAMLSIAWVLHKGCHPIVGLNTTARVDEAIAALQVTLTEEEIKYLEEPYKPQRQRC
SIO_010081: YPL088W
subclass of: SO_0000673
so part of: YPL088W
location: 381965..382993
location: region:381965-382993:1
so has part: feature:381965-382993:1:exon

NP_015237.1
type: Protein
SIO_000068: ncbiprotein

S000006009
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:381965-382993:1:exon

YPL087W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YDC1
locus tag: YPL087W
so part of: sequence
location: <383455..>384408
location: region:383455-384408:1
so has part: feature:383455-384408:1:exon
subclass of: SO_0000010

856018
type: Gene
SIO_000068: ncbigene

position:383455:1
position: 383455
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:384408:1
position: 384408
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:383455-384408:1:exon

YPL087W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YDC1
locus tag: YPL087W
product: alkaline dihydroceramidase
transcript id: NM_001183901.1
SIO_010081: YPL087W
subclass of: SO_0000673
so part of: YPL087W
location: <383455..>384408
location: region:383455-384408:1
so has part: feature:383455-384408:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:383455-384408:1:exon

YPL087W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YDC1
locus tag: YPL087W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10900202]
experiment: EXISTENCE:direct assay:GO:0071633 dihydroceramidase activity [PMID:10900202]
experiment: EXISTENCE:genetic interaction:GO:0046513 ceramide biosynthetic process [PMID:11694577]
experiment: EXISTENCE:mutant phenotype:GO:0046514 ceramide catabolic process [PMID:10900202]
note: Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity; YDC1 has a paralog, YPC1, that arose from the whole genome duplication
codon start: 1
product: alkaline dihydroceramidase
translation: MLFSWPYPEAPIEGYWGKPTSLIDWCEENYVVSPYIAEWSNTITNSIFLMTAFYSTYSAWRNKLETRYILIGMGFSLVGIGSWLFHMTLQYRYQLLDELPMLYATIIPSWSIFAETQEILIKDEKKRKESSFRIQMVISFIMCGIVTILTWIYVVVQKPAIFQVLYGILTLLVVVLSGWLTYYHVHDSFAKKNLFITMVMGMIPFVIGFICWQLDIHLCSFWIYIRRTYLALPLGVLLELHAWWHLLTGTGVYIFVVYLQYLRILTHGNPNDFLFIWRWGFFPELVRKGLPIGTSYSLEYLGPIVNTQVDDETKKNN
SIO_010081: YPL087W
subclass of: SO_0000673
so part of: YPL087W
location: 383455..384408
location: region:383455-384408:1
so has part: feature:383455-384408:1:exon

NP_015238.1
type: Protein
SIO_000068: ncbiprotein

S000006008
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:383455-384408:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1618; Autonomously Replicating Sequence
so part of: sequence
location: 384542..384789
location: region:384542-384789:1
so has part: feature:384542-384789:1:region

S000118415
type: SGD
SIO_000068: sgd

position:384542:1
position: 384542
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:384789:1
position: 384789
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:384542-384789:1:region

YPL086C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HPA1
alternative label: KAT9
alternative label: KTI8
alternative label: TOT3
gene: ELP3
locus tag: YPL086C
gene synonym: HPA1; KAT9; KTI8; TOT3
so part of: sequence
location: complement(<384773..>386446)
location: region:384773-386446:-1
so has part: feature:384773-386446:-1:exon
subclass of: SO_0000010

856019
type: Gene
SIO_000068: ncbigene

position:384773:-1
position: 384773
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:386446:-1
position: 386446
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:384773-386446:-1:exon

YPL086C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HPA1
alternative label: KAT9
alternative label: KTI8
alternative label: TOT3
gene: ELP3
locus tag: YPL086C
gene synonym: HPA1; KAT9; KTI8; TOT3
product: Elongator subunit ELP3
transcript id: NM_001183900.1
SIO_010081: YPL086C
subclass of: SO_0000673
so part of: YPL086C
location: complement(<384773..>386446)
location: region:384773-386446:-1
so has part: feature:384773-386446:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:384773-386446:-1:exon

YPL086C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HPA1
alternative label: KAT9
alternative label: KTI8
alternative label: TOT3
gene: ELP3
locus tag: YPL086C
gene synonym: HPA1; KAT9; KTI8; TOT3
experiment: EXISTENCE:direct assay:GO:0004402 histone acetyltransferase activity [PMID:10445034]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12139626]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12139626]
experiment: EXISTENCE:direct assay:GO:0033588 elongator holoenzyme complex [PMID:11689709]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:11689709]
note: Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin; human homolog ELP3 can partially complement yeast elp3 null mutant
codon start: 1
product: Elongator subunit ELP3
translation: MARHGKGPKTNKKKLAPEKERFIQCCADITLELTDSLTSGTTREINLNGLITKYSKKYKLKQQPRLTDIINSIPDQYKKYLLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLKQLGHSIDKVEYVLMGGTFMSLPKEYREDFIVKLHNALSGFNGNDIDEAILYSQQSLTKCVGITIETRPDYCTQTHLDDMLKYGCTRLEIGVQSLYEDVARDTNRGHTVRSVCETFAVSKDAGYKVVSHMMPDLPNVGMERDIEQFKEYFENPDFRTDGLKIYPTLVIRGTGLYELWKTGRYKSYSANALVDLVARILALVPPWTRIYRVQRDIPMPLVTSGVDNGNLRELALARMKDLGTTCRDVRTREVGIQEVHHKVQPDQVELIRRDYYANGGWETFLSYEDPKKDILIGLLRLRKASKKYTYRKEFTSQRTSIVRELHVYGSVVPLHSRDPRKFQHQGFGTLLMEEAERIAKEEHGSEKISVISGVGVRNYYGKLGYELDGPYMSKRI
SIO_010081: YPL086C
subclass of: SO_0000673
so part of: YPL086C
location: complement(384773..386446)
location: region:384773-386446:-1
so has part: feature:384773-386446:-1:exon

NP_015239.1
type: Protein
SIO_000068: ncbiprotein

S000006007
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:384773-386446:-1:exon

YPL085W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPF1
gene: SEC16
locus tag: YPL085W
gene synonym: LPF1
so part of: sequence
location: <387067..>393654
location: region:387067-393654:1
so has part: feature:387067-393654:1:exon
subclass of: SO_0000010

856020
type: Gene
SIO_000068: ncbigene

position:387067:1
position: 387067
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:393654:1
position: 393654
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:387067-393654:1:exon

YPL085W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPF1
gene: SEC16
locus tag: YPL085W
gene synonym: LPF1
product: Sec16p
transcript id: NM_001183899.1
SIO_010081: YPL085W
subclass of: SO_0000673
so part of: YPL085W
location: <387067..>393654
location: region:387067-393654:1
so has part: feature:387067-393654:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:387067-393654:1:exon

YPL085W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPF1
gene: SEC16
locus tag: YPL085W
gene synonym: LPF1
experiment: EXISTENCE:direct assay:GO:0012507 ER to Golgi transport vesicle membrane [PMID:7593161]
experiment: EXISTENCE:direct assay:GO:0043495 protein-membrane adaptor activity [PMID:12235121|PMID:7593161]
experiment: EXISTENCE:direct assay:GO:0048208 COPII vesicle coating [PMID:12235121]
experiment: EXISTENCE:direct assay:GO:0070971 endoplasmic reticulum exit site [PMID:22675024]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11694599]
experiment: EXISTENCE:mutant phenotype:GO:0070973 protein localization to endoplasmic reticulum exit site [PMID:22675024]
note: COPII vesicle coat protein required for ER transport vesicle budding; essential factor in endoplasmic reticulum exit site (ERES) formation, as well as in COPII-mediated ER-to-Golgi traffic; bound to periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p
codon start: 1
product: Sec16p
translation: MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDSIIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSENKIRNSGDDTSMLFQDDESDQKVPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYEGNEALKKSESCTAADERSYSEETSEDIFHGHDKQVVEGQNDFTGKNIENESQKLMGEGNHKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLGEVLPWESTDKNADVTSKSQEKHEDLFAASGNDEKLPWEVSDGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLASSEEEDTVPNTDNTTNLTSKPVEEKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKKSDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRKGSNNSNRPPVIPLGTQEPRSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPPIRARGVSNASVGSSASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQKQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENESSTDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFPNGDMIPNAYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDPLLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFSYDPKFKGFSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVRKLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWGQLDKSFNKYIGGDDIDALNKKNDKKKVFDGFTPGSSANSSTVDLTQTFTPFQAQVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTNEKALKSQQILEKKSTAYTPQFGQNHSVPMEKSNSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQNTLKDSADVTDETMDIEGPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERSSEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNNKASKLVEQHMAPPKPKSTDATKMNYSPYVPQSTAASADGDESTILKTSPAIYARTHQAHASNPSQYFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRK…
SIO_010081: YPL085W
subclass of: SO_0000673
so part of: YPL085W
location: 387067..393654
location: region:387067-393654:1
so has part: feature:387067-393654:1:exon

NP_015240.1
type: Protein
SIO_000068: ncbiprotein

S000006006
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:387067-393654:1:exon

YPL084W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ASI6
alternative label: LPF2
alternative label: NPI3
alternative label: VPS31
gene: BRO1
locus tag: YPL084W
gene synonym: ASI6; LPF2; NPI3; VPS31
so part of: sequence
location: <394038..>396572
location: region:394038-396572:1
so has part: feature:394038-396572:1:exon
subclass of: SO_0000010

856021
type: Gene
SIO_000068: ncbigene

position:394038:1
position: 394038
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:396572:1
position: 396572
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:394038-396572:1:exon

YPL084W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ASI6
alternative label: LPF2
alternative label: NPI3
alternative label: VPS31
gene: BRO1
locus tag: YPL084W
gene synonym: ASI6; LPF2; NPI3; VPS31
product: Bro1p
transcript id: NM_001183898.1
SIO_010081: YPL084W
subclass of: SO_0000673
so part of: YPL084W
location: <394038..>396572
location: region:394038-396572:1
so has part: feature:394038-396572:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:394038-396572:1:exon

YPL084W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ASI6
alternative label: LPF2
alternative label: NPI3
alternative label: VPS31
gene: BRO1
locus tag: YPL084W
gene synonym: ASI6; LPF2; NPI3; VPS31
experiment: EXISTENCE:direct assay:GO:0005515 protein binding [PMID:34908216]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12668726]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:12668726|PMID:15935782|PMID:34908216]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0035800 deubiquitinase activator activity [PMID:17446860]
experiment: EXISTENCE:direct assay:GO:2000158 positive regulation of ubiquitin-specific protease activity [PMID:17446860]
experiment: EXISTENCE:genetic interaction:GO:0016579 protein deubiquitination [PMID:15326198]
experiment: EXISTENCE:genetic interaction:GO:0070676 intralumenal vesicle formation [PMID:23444383]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:12062418]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:12668726]
experiment: EXISTENCE:mutant phenotype:GO:0007584 response to nutrient [PMID:8649366]
experiment: EXISTENCE:mutant phenotype:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:34908216]
experiment: EXISTENCE:mutant phenotype:GO:0036010 protein localization to endosome [PMID:15326198]
experiment: EXISTENCE:mutant phenotype:GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:14523026]
experiment: EXISTENCE:mutant phenotype:GO:0070676 intralumenal vesicle formation [PMID:23444383]
experiment: EXISTENCE:mutant phenotype:GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process [PMID:21070972]
experiment: EXISTENCE:mutant phenotype:GO:1904669 ATP export [PMID:26585826]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:27074665]
experiment: EXISTENCE:physical interaction:GO:0016579 protein deubiquitination [PMID:15326198]
note: Cytoplasmic class E vacuolar protein sorting (VPS) factor; coordinates protein sorting and deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
codon start: 1
product: Bro1p
translation: MKPYLFDLKLKDTEKLDWKKGLSSYLKKSYGSSQWRTFYDEKATSELDHLRNNANGELAPSSLSEQNLKYYSFLEHLYFRLGSKGSRLKMDFTWYDAEYSSAQKGLKYTQHTLAFEKSCTLFNIAVIFTQIARENINEDYKNSIANLTKAFSCFEYLSENFLNSPSVDLQSENTRFLANICHAEAQELFVLKLLNDQISSKQYTLISKLSRATCNLFQKCHDFMKEIDDDVAIYGEPKWKTTVTCKLHFYKSLSAYYHGLHLEEENRVGEAIAFLDFSMQQLISSLPFKTWLVEFIDFDGFKETLEKKQKELIKDNDFIYHESVPAVVQVDSIKALDAIKSPTWEKILEPYMQDVANKCDSLYRGIIPLDVYEKESIYSEEKATLLRKQVEETETANLEYSSFIEFTNLPRLLSDLEKQFSDGNIFSNTDTQGQLMRDQIQTWCKFIQTNEFRDIEEQMNKIVFKRKQILEILSALPNDQKENVTKLKSSLVAASNSDEKLFACVKPHIVEINLLNDNGKIWKKFDEFNRNTPPQPSLLDIDDTKNDKILELLKQVKGHAEDLRTLKEERSRNLSELRDEINNDDITKLLIINKGKSDVELKDLFEVELEKFEPLSTRIEATIYKQSSMIDDIKAKLDEIFHLSNFKDKSSGEEKFLEDRKNFFDKLQEAVKSFSIFASDLPKGIEFYDSLFNMSRDLAERVRVAKQTEDSTANSPAPPLPPLDSKASVVGGPPLLPQKSAAFQSLSRQGLNLGDQFQNLKISAGSDLPQGPGIPPRTYEASPYAATPTMAAPPVPPKQSQEDMYDLRRRKAVENEERELQENPTSFYNRPSVFDENMYSKYSS
SIO_010081: YPL084W
subclass of: SO_0000673
so part of: YPL084W
location: 394038..396572
location: region:394038-396572:1
so has part: feature:394038-396572:1:exon

NP_015241.1
type: Protein
SIO_000068: ncbiprotein

S000006005
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:394038-396572:1:exon

YPL083C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEN54
locus tag: YPL083C
so part of: sequence
location: complement(<396702..>398105)
location: region:396702-398105:-1
so has part: feature:396702-398105:-1:exon
subclass of: SO_0000010

856022
type: Gene
SIO_000068: ncbigene

position:396702:-1
position: 396702
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:398105:-1
position: 398105
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:396702-398105:-1:exon

YPL083C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEN54
locus tag: YPL083C
product: tRNA splicing endonuclease subunit SEN54
transcript id: NM_001183897.1
SIO_010081: YPL083C
subclass of: SO_0000673
so part of: YPL083C
location: complement(<396702..>398105)
location: region:396702-398105:-1
so has part: feature:396702-398105:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:396702-398105:-1:exon

YPL083C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEN54
locus tag: YPL083C
experiment: EXISTENCE:direct assay:GO:0000213 tRNA-intron endonuclease activity [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0000214 tRNA-intron endonuclease complex [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0000379 tRNA-type intron splice site recognition and cleavage [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:12925762|PMID:16407407]
experiment: EXISTENCE:mutant phenotype:GO:0005741 mitochondrial outer membrane [PMID:12925762]
note: Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease (Sen complex) is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface
codon start: 1
product: tRNA splicing endonuclease subunit SEN54
translation: MQFAGKKTDQVTTSNPGFEEEEEEEEELQQDWSQLASLVSKNAALSLPKRGEKDYEPDGTNLQDLLLYNASKAMFDTISDSIRGTTVKSEVRGYYVPHKHQAVLLKPKGSFMQTMGRADSTGELWLDFHEFVYLAERGTILPYYRLEAGSNKSSKHETEILLSMEDLYSLFSSQQEMDQYFVFAHLKRLGFILKPSNQEAAVKTSFFPLKKQRSNLQAITWRLLSLFKIQELSLFSGFFYSKWNFFFRKYTTSPQLYQGLNRLVRSVAVPKNKKELLDAQSDREFQKVKDIPLTFKVWKPHSNFKKRDPGLPDFQVFVYNKNDDLQHFPTYKELRSMFSSLDYKFEFLSEIEDDDDWETNSYVEDIPRKEYIHKRSAKSQTEKSESSMKASFQKKTAQSSTKKKRKAYPPHIQQNRRLKTGYRSFIIAIMDNGLISFVKMSEADFGSESVWYTPNTQKKVDQRWKKH
SIO_010081: YPL083C
subclass of: SO_0000673
so part of: YPL083C
location: complement(396702..398105)
location: region:396702-398105:-1
so has part: feature:396702-398105:-1:exon

NP_015242.1
type: Protein
SIO_000068: ncbiprotein

S000006004
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:396702-398105:-1:exon

YPL082C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BUR3
alternative label: END10
alternative label: LPF4
gene: MOT1
locus tag: YPL082C
gene synonym: BUR3; END10; LPF4
so part of: sequence
location: complement(<398480..>404083)
location: region:398480-404083:-1
so has part: feature:398480-404083:-1:exon
subclass of: SO_0000010

856023
type: Gene
SIO_000068: ncbigene

position:398480:-1
position: 398480
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:404083:-1
position: 404083
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:398480-404083:-1:exon

YPL082C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BUR3
alternative label: END10
alternative label: LPF4
gene: MOT1
locus tag: YPL082C
gene synonym: BUR3; END10; LPF4
product: DNA-binding ATPase
transcript id: NM_001183896.1
SIO_010081: YPL082C
subclass of: SO_0000673
so part of: YPL082C
location: complement(<398480..>404083)
location: region:398480-404083:-1
so has part: feature:398480-404083:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:398480-404083:-1:exon

YPL082C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BUR3
alternative label: END10
alternative label: LPF4
gene: MOT1
locus tag: YPL082C
gene synonym: BUR3; END10; LPF4
experiment: EXISTENCE:direct assay:GO:0000228 nuclear chromosome [PMID:11880621]
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:22298788]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:21976730|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9234740]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:9234740]
experiment: EXISTENCE:direct assay:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:17296733]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:17296733]
experiment: EXISTENCE:mutant phenotype:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:17296733]
experiment: EXISTENCE:mutant phenotype:GO:0045892 negative regulation of DNA-templated transcription [PMID:24459134]
experiment: EXISTENCE:mutant phenotype:GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly [PMID:15861138|PMID:21976730]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:27226635]
experiment: EXISTENCE:physical interaction:GO:0017025 TBP-class protein binding [PMID:8083216]
note: Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes
codon start: 1
product: DNA-binding ATPase
translation: MTSRVSRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPNESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLSDWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANENKSNANKKSARMLAMARRKKKMSAKNTPKHPVDITESSVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLRNSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLNQSDDDVQSVAASILTPITSEFVKLNNSTIEILVTTIWSLLARLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHPSEWSFKSLVPKLYPFLRHSISSVRRAVLNLLIAFLSIKDDSTKNWLNGKVFRLVFQNILLEQNPELLQLSFDVYVALLEHYKVKHTEKTLDHVFSKHLQPILHLLNTPVGEKGKNYAMESQYILKPSQHYQLHPEKKRSISETTTDSDIPIPKNNEHINIDAPMIAGDITLLGLDVILNTRIMGAKAFALTLSMFQDSTLQSFFTNVLVRCLELPFSTPRMLAGIIVSQFCSSWLQKHPEGEKLPSFVSEIFSPVMNKQLLNRDEFPVFRELVPSLKALRTQCQSLLATFVDVGMLPQYKLPNVAIVVQGETEAGPHAFGVETAEKVYGEYYDKMFKSMNNSYKLLAKKPLEDSKHRVLMAINSAKESAKLRTGSILANYASSILLFDGLPLKLNPIIRSLMDSVKEERNEKLQTMAGESVVHLIQQLLENNKVNVSGKIVKNLCGFLCVDTSEVPDFSVNAEYKEKILTLIKESNSIAAQDDINLAKMSEEAQLKRKGGLITLKILFEVLGPSILQKLPQLRSILFDSLSDHENEEASKVDNEQGQKIVDSFGVLRALFPFMSDSLRSSEVFTRFPVLLTFLRSNLSVFRYSAARTFADLAKISSVEVMAYTIREILPLMNSAGSLSDRQGSTELIYHLSLSMETDVLPYVIFLIVPLLGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAIKATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYAPFLKVVVYAGGPTVRLTLRPQLSDADIIVTSYDVARNDLAVLNKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIADGKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGIGEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPDNVTSQDNEEKNNGDSQAAKGMEDIANETGLTGKAKEALGELKELWDPSQYEEEYNLDTFIKTLR
SIO_010081: YPL082C
subclass of: SO_0000673
so part of: YPL082C
location: complement(398480..404083)
location: region:398480-404083:-1
so has part: feature:398480-404083:-1:exon

NP_015243.1
type: Protein
SIO_000068: ncbiprotein

S000006003
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:398480-404083:-1:exon

YPL081W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPS9A
locus tag: YPL081W
so part of: sequence
location: <404950..>406044
location: region:404950-406044:1
so has part: feature:404950-406044:1:exon
subclass of: SO_0000010

856024
type: Gene
SIO_000068: ncbigene

position:404950:1
position: 404950
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:406044:1
position: 406044
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:404950-406044:1:exon

YPL081W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPS9A
locus tag: YPL081W
product: ribosomal 40S subunit protein S9A
transcript id: NM_001183895.1
SIO_010081: YPL081W
subclass of: SO_0000673
so part of: YPL081W
location: join(<404950..404956,405458..>406044)
location: region:404950-406044:1
so has part: feature:404950-404956:1:exon
so has part: feature:405458-406044:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:404950-404956:1:exon

position:404956:1
position: 404956
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:405458-406044:1:exon

position:405458:1
position: 405458
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL081W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPS9A
locus tag: YPL081W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0019843 rRNA binding [PMID:16540469]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
experiment: EXISTENCE:mutant phenotype:GO:0019843 rRNA binding [PMID:16540469]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S9 and bacterial S4; RPS9A has a paralog, RPS9B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S9A
translation: MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAADEADEADEE
SIO_010081: YPL081W
subclass of: SO_0000673
so part of: YPL081W
location: join(404950..404956,405458..406044)
location: region:404950-406044:1
so has part: feature:404950-404956:1:exon
so has part: feature:405458-406044:1:exon

NP_015244.1
type: Protein
SIO_000068: ncbiprotein

S000006002
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:404950-404956:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:405458-406044:1:exon

YPL080C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL080C
so part of: sequence
location: complement(<406172..>406498)
location: region:406172-406498:-1
so has part: feature:406172-406498:-1:exon
subclass of: SO_0000010

856025
type: Gene
SIO_000068: ncbigene

position:406172:-1
position: 406172
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:406498:-1
position: 406498
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:406172-406498:-1:exon

YPL080C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL080C
product: uncharacterized protein
transcript id: NM_001348884.1
SIO_010081: YPL080C
subclass of: SO_0000673
so part of: YPL080C
location: complement(<406172..>406498)
location: region:406172-406498:-1
so has part: feature:406172-406498:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:406172-406498:-1:exon

YPL080C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL080C
note: hypothetical protein; conserved across S. cerevisiae strains
codon start: 1
product: uncharacterized protein
translation: MDGSYLTHRYCALKRPYTAHLLLLDFSKDEVTKNVWRWKGTDVKLHKMGRKSIVAAVYNQAHPSHPPLYHLGNLNGDKYVASPPSRMKAVSLSFAFTFLYYYFPLPTN
SIO_010081: YPL080C
subclass of: SO_0000673
so part of: YPL080C
location: complement(406172..406498)
location: region:406172-406498:-1
so has part: feature:406172-406498:-1:exon

NP_001335822.1
type: Protein
SIO_000068: ncbiprotein

S000006001
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:406172-406498:-1:exon

YPL079W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL21B
locus tag: YPL079W
so part of: sequence
location: <406636..>407539
location: region:406636-407539:1
so has part: feature:406636-407539:1:exon
subclass of: SO_0000010

856026
type: Gene
SIO_000068: ncbigene

position:406636:1
position: 406636
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:407539:1
position: 407539
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:406636-407539:1:exon

YPL079W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL21B
locus tag: YPL079W
product: ribosomal 60S subunit protein L21B
transcript id: NM_001183893.1
SIO_010081: YPL079W
subclass of: SO_0000673
so part of: YPL079W
location: join(<406636..406646,407068..>407539)
location: region:406636-407539:1
so has part: feature:406636-406646:1:exon
so has part: feature:407068-407539:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:406636-406646:1:exon

position:406646:1
position: 406646
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:407068-407539:1:exon

position:407068:1
position: 407068
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL079W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL21B
locus tag: YPL079W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L21B; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21B has a paralog, RPL21A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L21B
translation: MGKSHGYRSRTRYMFQRDFRKHGAVHMSTYLKIYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI
SIO_010081: YPL079W
subclass of: SO_0000673
so part of: YPL079W
location: join(406636..406646,407068..407539)
location: region:406636-407539:1
so has part: feature:406636-406646:1:exon
so has part: feature:407068-407539:1:exon

NP_015246.1
type: Protein
SIO_000068: ncbiprotein

S000006000
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:406636-406646:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:407068-407539:1:exon

YPL078C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPF7
gene: ATP4
locus tag: YPL078C
gene synonym: LPF7
so part of: sequence
location: complement(<408010..>408744)
location: region:408010-408744:-1
so has part: feature:408010-408744:-1:exon
subclass of: SO_0000010

856027
type: Gene
SIO_000068: ncbigene

position:408010:-1
position: 408010
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:408744:-1
position: 408744
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:408010-408744:-1:exon

YPL078C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPF7
gene: ATP4
locus tag: YPL078C
gene synonym: LPF7
product: F1F0 ATP synthase subunit 4
transcript id: NM_001183892.1
SIO_010081: YPL078C
subclass of: SO_0000673
so part of: YPL078C
location: complement(<408010..>408744)
location: region:408010-408744:-1
so has part: feature:408010-408744:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:408010-408744:-1:exon

YPL078C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPF7
gene: ATP4
locus tag: YPL078C
gene synonym: LPF7
experiment: EXISTENCE:direct assay:GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk [PMID:18722382]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0015986 proton motive force-driven ATP synthesis [PMID:20691145]
experiment: EXISTENCE:direct assay:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:20691145]
experiment: EXISTENCE:mutant phenotype:GO:0015986 proton motive force-driven ATP synthesis [PMID:8068646]
experiment: EXISTENCE:mutant phenotype:GO:0046961 proton-transporting ATPase activity, rotational mechanism [PMID:8068646]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:18293929]
note: Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase; ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; contributes to the oligomerization of the complex, which in turn determines the shape of inner membrane cristae; phosphorylated
codon start: 1
product: F1F0 ATP synthase subunit 4
translation: MSMSMGVRGLALRSVSKTLFSQGVRCPSMVIGARYMSSTPEKQTDPKAKANSIINAIPGNNILTKTGVLGTSAAAVIYAISNELYVINDESILLLTFLGFTGLVAKYLAPAYKDFADARMKKVSDVLNASRNKHVEAVKDRIDSVSQLQNVAETTKVLFDVSKETVELESEAFELKQKVELAHEAKAVLDSWVRYEASLRQLEQRQLAKSVISRVQSELGNPKFQEKVLQQSISEIEQLLSKLK
SIO_010081: YPL078C
subclass of: SO_0000673
so part of: YPL078C
location: complement(408010..408744)
location: region:408010-408744:-1
so has part: feature:408010-408744:-1:exon

NP_015247.1
type: Protein
SIO_000068: ncbiprotein

S000005999
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:408010-408744:-1:exon

YPL077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL077C
so part of: sequence
location: complement(<409368..>410090)
location: region:409368-410090:-1
so has part: feature:409368-410090:-1:exon
subclass of: SO_0000010

856028
type: Gene
SIO_000068: ncbigene

position:409368:-1
position: 409368
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:410090:-1
position: 410090
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:409368-410090:-1:exon

YPL077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL077C
product: uncharacterized protein
transcript id: NM_001183891.1
SIO_010081: YPL077C
subclass of: SO_0000673
so part of: YPL077C
location: complement(<409368..>410090)
location: region:409368-410090:-1
so has part: feature:409368-410090:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:409368-410090:-1:exon

YPL077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL077C
note: hypothetical protein; regulates PIS1 expression; mutant displays spore wall assembly defect in ether sensitivity screen; YPL077C is not an essential gene; YPL077C has a paralog, YBR197C, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MKDLQKKSSVRRQITNEDDERYGEDSIHDLPRTIPNVNPYIRNSGFRPSYSSQIPSTRSLFNNYYNRSSANTVGNDTIDTDSVSYNGVAKFRRNSVDIPLQTHNRLEVRPIIDRQDYLWREIDALDDVKRQAQATELYDQFPPGFENKLMQLRQAHSKLLQVLRDRNAKIEEEQRREVAVATAAAMMTRTPSPTGKSVGDEATSNNMHSSSAIRNPNGPTVDPEEGKYIQELVNTIRELQ
SIO_010081: YPL077C
subclass of: SO_0000673
so part of: YPL077C
location: complement(409368..410090)
location: region:409368-410090:-1
so has part: feature:409368-410090:-1:exon

NP_015248.1
type: Protein
SIO_000068: ncbiprotein

S000005998
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:409368-410090:-1:exon

YPL076W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GCR4
gene: GPI2
locus tag: YPL076W
gene synonym: GCR4
so part of: sequence
location: <410443..>411285
location: region:410443-411285:1
so has part: feature:410443-411285:1:exon
subclass of: SO_0000010

856029
type: Gene
SIO_000068: ncbigene

position:410443:1
position: 410443
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:411285:1
position: 411285
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:410443-411285:1:exon

YPL076W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GCR4
gene: GPI2
locus tag: YPL076W
gene synonym: GCR4
product: phosphatidylinositol N-acetylglucosaminyltransferase
transcript id: NM_001183890.1
SIO_010081: YPL076W
subclass of: SO_0000673
so part of: YPL076W
location: <410443..>411285
location: region:410443-411285:1
so has part: feature:410443-411285:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:410443-411285:1:exon

YPL076W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GCR4
gene: GPI2
locus tag: YPL076W
gene synonym: GCR4
EC number: 2.4.1.198
experiment: EXISTENCE:curator inference:GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity []
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006506 GPI anchor biosynthetic process [PMID:7768896]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:7768896]
experiment: EXISTENCE:physical interaction:GO:0000506 glycosylphosphatidylinositol-N- acetylglucosaminyltransferase (GPI-GnT) complex [PMID:15163411]
note: Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositol
codon start: 1
product: phosphatidylinositol N-acetylglucosaminyltransferase
translation: MTRSPWKRLLWLKQEYPDNYTDPSFIELRARQKAESNQKSDRKLSEAARAQIRLDFISFYQTILNTSFIYITFTYIYYYGFDPIPPTIFLSFITLIISRTKVDPLLSSFMDVKSSLIITFAMLTLSPVLKSLSKTTASDSIWTLSFWLTLWYIFVISSTKSKDKPSNLSTNILVALVAVLSSRLSTTIDVFCFLLICIQLNIILPTYLSVTNKVVPIISNIIVYSFLNVALGWIYMLLIFFASVFYITVLPKWFIYWKINYHKRDNDLLSTWDARTPILD
SIO_010081: YPL076W
subclass of: SO_0000673
so part of: YPL076W
location: 410443..411285
location: region:410443-411285:1
so has part: feature:410443-411285:1:exon

NP_015249.1
type: Protein
SIO_000068: ncbiprotein

S000005997
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:410443-411285:1:exon

YPL075W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPF10
alternative label: SIT3
gene: GCR1
locus tag: YPL075W
gene synonym: LPF10; SIT3
so part of: sequence
location: <412254..>415362
location: region:412254-415362:1
so has part: feature:412254-415362:1:exon
subclass of: SO_0000010

856030
type: Gene
SIO_000068: ncbigene

position:412254:1
position: 412254
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:415362:1
position: 415362
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:412254-415362:1:exon

YPL075W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPF10
alternative label: SIT3
gene: GCR1
locus tag: YPL075W
gene synonym: LPF10; SIT3
product: transcription regulator GCR1
transcript id: NM_001183889.1
SIO_010081: YPL075W
subclass of: SO_0000673
so part of: YPL075W
location: join(<412254..412261,413013..>415362)
location: region:412254-415362:1
so has part: feature:412254-412261:1:exon
so has part: feature:413013-415362:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:412254-412261:1:exon

position:412261:1
position: 412261
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:413013-415362:1:exon

position:413013:1
position: 413013
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL075W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPF10
alternative label: SIT3
gene: GCR1
locus tag: YPL075W
gene synonym: LPF10; SIT3
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:10455229|PMID:12655409|PMID:1588965|PMID:1946357|PMI D:7808400|PMID:9271107|PMID:9335590]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:9335590]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:15817685]
experiment: EXISTENCE:mutant phenotype:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:12655409]
experiment: EXISTENCE:mutant phenotype:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:1588965]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:9271107]
experiment: EXISTENCE:mutant phenotype:GO:0034728 nucleosome organization [PMID:2854200]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:10455229|PMID:15789351|PMID:9335590|PMID:11333224|PM ID:3547083|PMID:7808400|PMID:10510295]
experiment: EXISTENCE:mutant phenotype:GO:0060963 positive regulation of ribosomal protein gene transcription by RNA polymerase II [PMID:11333224]
experiment: EXISTENCE:mutant phenotype:GO:0061435 positive regulation of transcription from a mobile element promoter [PMID:9271107]
note: Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p; contains a long intron, which allows multiple RNA and protein isoforms with varying expression levels depending on glucose availability
codon start: 1
product: transcription regulator GCR1
translation: MVCTSTSSNFYSIAQYILQSYFKVNVDSLNSLKLVDLIVDQTYPDSLTLRKLNEGATGQPYDYFNTVSRDADISKCPIFALTIFFVIRWSHPNPPISIENFTTVPLLDSNFISLNSNPLLYIQNQNPNSNSSVKVSRSQTFEPSKELIDLVFPWLSYLKQDMLLIDRTNYKLYSLCELFEFMGRVAIQDLRYLSQHPLLLPNIVTFISKFIPELFQNEEFKGIGSIKNSNNNALNNVTGIETQFLNPSTEEVSQKVDSYFMELSKKLTTENIRLSQEITQLKADMNSVGNVCNQILLLQRQLLSGNQAIGSKSENIVSSTGGGILILDKNSINSNVLSNLVQSIDPNHSKPNGQAQTHQRGPKGQSHAQVQSTNSPALAPINMFPSLSNSIQPMLGTLAPQPQDIVQKRKLPLPGSIASAATGSPFSPSPVGESPYSKRFKLDDKPTPSQTALDSLLTKSISSPRLPLSTLANTAVTESFRSPQQFQHSPDFVVGGSSSSTTENNSKKVNEDSPSSSSKLAERPRLPNNDSTTSMPESPTEVAGDDVDREKPPESSKSEPNDNSPESKDPEKNGKNSNPLGTDADKPVPISNIHNSTEAANSSGTVTKTAPSFPQSSSKFEIINKKDTKAGPNEAIKYKLSRENKTIWDLYAEWYIGLNGKSSIKKLIENYGWRRWKVSEDSHFFPTRRIIMDYIETECDRGIKLGRFTNPQQPREDIRKILVGDLEKFRINNGLTLNSLSLYFRNLTKNNKEICIFENFKNWNVRSMTEEEKLKYCKRRHNTPS
SIO_010081: YPL075W
subclass of: SO_0000673
so part of: YPL075W
location: join(412254..412261,413013..415362)
location: region:412254-415362:1
so has part: feature:412254-412261:1:exon
so has part: feature:413013-415362:1:exon

NP_015250.1
type: Protein
SIO_000068: ncbiprotein

S000005996
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:412254-412261:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:413013-415362:1:exon

YPL074W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YTA6
locus tag: YPL074W
so part of: sequence
location: <415763..>418027
location: region:415763-418027:1
so has part: feature:415763-418027:1:exon
subclass of: SO_0000010

856031
type: Gene
SIO_000068: ncbigene

position:415763:1
position: 415763
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:418027:1
position: 418027
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:415763-418027:1:exon

YPL074W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YTA6
locus tag: YPL074W
product: putative AAA family ATPase YTA6
transcript id: NM_001183888.1
SIO_010081: YPL074W
subclass of: SO_0000673
so part of: YPL074W
location: <415763..>418027
location: region:415763-418027:1
so has part: feature:415763-418027:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:415763-418027:1:exon

YPL074W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YTA6
locus tag: YPL074W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:11553699]
experiment: EXISTENCE:mutant phenotype:GO:0045727 positive regulation of translation [PMID:32639961]
note: Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress
codon start: 1
product: putative AAA family ATPase YTA6
translation: MAHEKFSIPENFTLAQSLQLLYSVVKNQYKNLADLIINSKGNKDTVTYGKIHKNLDTLLVYVNEGLRKIEKTYTLKKGLGNLVVDHPELRSIIEDFQILGQDIRIARRKAETLMAEGNGSPSLSSSSSVLGLGTGNGLRFPKLWRMGSKRDKLKEADEKEAKINKQADNIRRARKLEEEKKLGAKLQYERDLELQREKLIELKVKEKVEFEVAQKLEEERVKREEEERKHREQAEKKRISTLKHERKTNYKSRASLDNFSSSSKSSGKIDNSLIKRRSLDVVRTSGERVRTPVRKSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKPTPPLKKRYDYKKPTVNRPIIKSPTLNRQNSKSSRNIPTNSKLKASKSNTNKVSRRNEQNLEPSSPVLVSATAVPAESKPMRSKSGTPDKESSASSSLDSRKEDILKSVQGVDRNACEQILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSDNENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARRRFSRKLYIPLPDYETRLYHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLGDKLMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKFGSNGS
SIO_010081: YPL074W
subclass of: SO_0000673
so part of: YPL074W
location: 415763..418027
location: region:415763-418027:1
so has part: feature:415763-418027:1:exon

NP_015251.1
type: Protein
SIO_000068: ncbiprotein

S000005995
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:415763-418027:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1619; Autonomously Replicating Sequence
so part of: sequence
location: 418138..418364
location: region:418138-418364:1
so has part: feature:418138-418364:1:region

S000118416
type: SGD
SIO_000068: sgd

position:418138:1
position: 418138
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:418364:1
position: 418364
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:418138-418364:1:region

YPL072W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBP16
locus tag: YPL072W
so part of: sequence
location: <418512..>420011
location: region:418512-420011:1
so has part: feature:418512-420011:1:exon
subclass of: SO_0000010

856032
type: Gene
SIO_000068: ncbigene

position:418512:1
position: 418512
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:420011:1
position: 420011
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:418512-420011:1:exon

YPL072W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBP16
locus tag: YPL072W
product: putative ubiquitin-specific protease UBP16
transcript id: NM_001183886.1
SIO_010081: YPL072W
subclass of: SO_0000673
so part of: YPL072W
location: <418512..>420011
location: region:418512-420011:1
so has part: feature:418512-420011:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:418512-420011:1:exon

YPL072W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBP16
locus tag: YPL072W
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:12914939|PMID:16407407]
note: Putative deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria
codon start: 1
product: putative ubiquitin-specific protease UBP16
translation: MSWIKNVTESPTSLIKKVSCGLIIAASLYAIAPSLSALVFGDSKQSIGKYTTVGLINRGNDCFITSSLQGLAGIPRFVEYLKRIRTVLLELETKLSNNAKGDNPTVDNTTRHSRLENSSNSLAPLHESLTSLILDLISVKDRKTSISPKIVINTLESIFKSKISSKQNDAHEFTLILLQTLQEERSKLIDYSKQICNLNIPKFPFEGETSKFLVCLKCKGLSEPSYKQTFIRELSVPQQTSENLSNILAHDETEIIDDYSCLICQIRAILNHEEYRNFKDCTPDEILMLDRLKNYATKAPINENLPFEVEQYVKRYSKGNLQVSNIKGKVIKKDVVVQLPDILIVHLSRSTFNGITYSRNPCNVKFGERITLSEYTLAESGTITENRQVKYNLKSVVKHTGSHSSGHYMCYRRKTEIRFGKEDESSFRRAPVVNNEVNKNREQNVAHNDYKKSRYKKVKNALRYPYWQISDTAIKESTASTVLNEQKYAYMLYYERVNK
SIO_010081: YPL072W
subclass of: SO_0000673
so part of: YPL072W
location: 418512..420011
location: region:418512-420011:1
so has part: feature:418512-420011:1:exon

NP_015253.1
type: Protein
SIO_000068: ncbiprotein

S000005993
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:418512-420011:1:exon

YPL071C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL071C
so part of: sequence
location: complement(<420048..>420518)
location: region:420048-420518:-1
so has part: feature:420048-420518:-1:exon
subclass of: SO_0000010

856034
type: Gene
SIO_000068: ncbigene

position:420048:-1
position: 420048
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:420518:-1
position: 420518
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:420048-420518:-1:exon

YPL071C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL071C
product: uncharacterized protein
transcript id: NM_001183885.1
SIO_010081: YPL071C
subclass of: SO_0000673
so part of: YPL071C
location: complement(<420048..>420518)
location: region:420048-420518:-1
so has part: feature:420048-420518:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:420048-420518:-1:exon

YPL071C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL071C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
codon start: 1
product: uncharacterized protein
translation: MSSRFARSNGNPNHIRKRNHSPDPIGIDNYKRKRLIIDLENLSLNDKGPKNGHADDNNLIHNNIVFTDAIDDKVLKEIIKCSTSKRGDNDLFYDKIWERLREKRLQIIKWVDYKEIAYLSWWKWFHNQMTSKYTYDGEADTDVEMMAVDTDVDMDA
SIO_010081: YPL071C
subclass of: SO_0000673
so part of: YPL071C
location: complement(420048..420518)
location: region:420048-420518:-1
so has part: feature:420048-420518:-1:exon

NP_015254.1
type: Protein
SIO_000068: ncbiprotein

S000005992
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:420048-420518:-1:exon

YPL070W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MUK1
locus tag: YPL070W
so part of: sequence
location: <420948..>422786
location: region:420948-422786:1
so has part: feature:420948-422786:1:exon
subclass of: SO_0000010

856035
type: Gene
SIO_000068: ncbigene

position:420948:1
position: 420948
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:422786:1
position: 422786
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:420948-422786:1:exon

YPL070W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MUK1
locus tag: YPL070W
product: guanine nucleotide exchange factor MUK1
transcript id: NM_001183884.1
SIO_010081: YPL070W
subclass of: SO_0000673
so part of: YPL070W
location: <420948..>422786
location: region:420948-422786:1
so has part: feature:420948-422786:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:420948-422786:1:exon

YPL070W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MUK1
locus tag: YPL070W
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:23264632|PMID:23612966]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:23612966|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006895 Golgi to endosome transport [PMID:23612966]
experiment: EXISTENCE:genetic interaction:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:23612966]
experiment: EXISTENCE:genetic interaction:GO:0036010 protein localization to endosome [PMID:23264632]
note: Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain
codon start: 1
product: guanine nucleotide exchange factor MUK1
translation: MARQLFTPPITNPRFDPNQSIRESYKNTTGGMQFQQNLHEDQNDNERSSCDGDENSTTGERLENNKSPILTKQEIDEALNTVTNLPPELSKLIDIFIDDLKQPKYVRPLSVLQLSSLFQSFYIKFDKASFQHVSSANNNGYYFSGGGSSSFLAAKETLSSGLSGIFGRSRSSSGNSLMRPRRSSSLFSNESISNSTNATQMLSPEEIKKQLKINELNNMKIEKYMELCERDVFKKILIVGTSVSSPNKMKTFKPHQLQTFKVGNLFRNSVEFTEYNKLLNEKILCLSKLSTMNKINLIKFLSLNNGIDPEPKFEEIKDILYEFTYHSISPCEKIKALLKLHEIMTYSQEMSNDDYLSLLIYYIITIVPRDIFLNAEFIRLFRYKKKLVETESFALTNLEAALVFVEGLTKNDFSNELQDKLTVNESKILENSISSRVSLPSKTAIMHKNNGNNGSNLGDIVTPTIQRPDVTRSNSYDGFRTVFDSSLKNIIGKIRSYTPPHPNNTSNNNLHSSNNLNIPRSSSQLSMELSNRDTTEMSRDGSRSTSSSSRSSASLEHGNREFTGDLTVTASINGADKKEFQKSWKKYKGYKFEDLTICELRDLFEIYQKMMQ
SIO_010081: YPL070W
subclass of: SO_0000673
so part of: YPL070W
location: 420948..422786
location: region:420948-422786:1
so has part: feature:420948-422786:1:exon

NP_015255.1
type: Protein
SIO_000068: ncbiprotein

S000005991
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:420948-422786:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1620; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 422786..422885
location: region:422786-422885:1
so has part: feature:422786-422885:1:region

S000130200
type: SGD
SIO_000068: sgd

position:422885:1
position: 422885
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422786-422885:1:region

YPL069C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BTS1
locus tag: YPL069C
so part of: sequence
location: complement(<422885..>423892)
location: region:422885-423892:-1
so has part: feature:422885-423892:-1:exon
subclass of: SO_0000010

856036
type: Gene
SIO_000068: ncbigene

position:422885:-1
position: 422885
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:423892:-1
position: 423892
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422885-423892:-1:exon

YPL069C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BTS1
locus tag: YPL069C
product: farnesyltranstransferase
transcript id: NM_001183883.1
SIO_010081: YPL069C
subclass of: SO_0000673
so part of: YPL069C
location: complement(<422885..>423892)
location: region:422885-423892:-1
so has part: feature:422885-423892:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:422885-423892:-1:exon

YPL069C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BTS1
locus tag: YPL069C
EC number: 2.5.1.1
EC number: 2.5.1.10
EC number: 2.5.1.29
experiment: EXISTENCE:direct assay:GO:0004311 farnesyltranstransferase activity [PMID:7665600]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016114 terpenoid biosynthetic process [PMID:7665600]
experiment: EXISTENCE:mutant phenotype:GO:0016114 terpenoid biosynthetic process [PMID:7665600]
note: Geranylgeranyl diphosphate synthase (GGPPS); increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic
codon start: 1
product: farnesyltranstransferase
translation: MEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNLKDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPDLASHSDTATNLHDELLYIIDHLSEL
SIO_010081: YPL069C
subclass of: SO_0000673
so part of: YPL069C
location: complement(422885..423892)
location: region:422885-423892:-1
so has part: feature:422885-423892:-1:exon

NP_015256.1
type: Protein
SIO_000068: ncbiprotein

S000005990
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:422885-423892:-1:exon

YPL068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL068C
so part of: sequence
location: complement(<424215..>425096)
location: region:424215-425096:-1
so has part: feature:424215-425096:-1:exon
subclass of: SO_0000010

856037
type: Gene
SIO_000068: ncbigene

position:424215:-1
position: 424215
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:425096:-1
position: 425096
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:424215-425096:-1:exon

YPL068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL068C
product: uncharacterized protein
transcript id: NM_001183882.1
SIO_010081: YPL068C
subclass of: SO_0000673
so part of: YPL068C
location: complement(<424215..>425096)
location: region:424215-425096:-1
so has part: feature:424215-425096:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:424215-425096:-1:exon

YPL068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL068C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and is induced in response to the DNA-damaging agent MMS
codon start: 1
product: uncharacterized protein
translation: MHMQLRKRKRVDYSGRNQTSDPPSTTTAAVPSIIVPKKRKVVAQNMVSPAIRATTTTLGTSNIIIPKPLQRPKFHNSASLSSPDDDPEKISVLEVQKNLSNLIKRQQRLFYKDIHKPTLAGLKNFEMLRLPNDLKLLQNIVNLLYSFEQLNSDSKTRPVTTSKLKASSQAHSDKLKKMLAERKPPFSHPSHSGTAYHNDIIHEIANLHSINLVDLINLEVYNNNCHTNNTALQTTANSLTLNSIIKKLDKPILKERNNSLVWPHKSRFKAKRNQPSPGQSLINNTDITLYNDV
SIO_010081: YPL068C
subclass of: SO_0000673
so part of: YPL068C
location: complement(424215..425096)
location: region:424215-425096:-1
so has part: feature:424215-425096:-1:exon

NP_015257.1
type: Protein
SIO_000068: ncbiprotein

S000005989
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:424215-425096:-1:exon

YPL067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HTC1
locus tag: YPL067C
so part of: sequence
location: complement(<425251..>425847)
location: region:425251-425847:-1
so has part: feature:425251-425847:-1:exon
subclass of: SO_0000010

856038
type: Gene
SIO_000068: ncbigene

position:425251:-1
position: 425251
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:425847:-1
position: 425847
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:425251-425847:-1:exon

YPL067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HTC1
locus tag: YPL067C
product: Htc1p
transcript id: NM_001183881.1
SIO_010081: YPL067C
subclass of: SO_0000673
so part of: YPL067C
location: complement(<425251..>425847)
location: region:425251-425847:-1
so has part: feature:425251-425847:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:425251-425847:-1:exon

YPL067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HTC1
locus tag: YPL067C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene
codon start: 1
product: Htc1p
translation: MQQDIVNDHQEEAQGWKWEQIKEIIESGELARLKRSRQMTDKYHEHKKRTAGLDMNQYVLQKLGWSLDEPQLENAAAKAFSSSTLYAVRANDFPYNFEPGVVHLVLWSKVALPVHSPDKAVREAARARMNAFLQAQPLLRPLLSSGHVAWFVNYPELQSVARIFHAHVLLFFPRERYSAEQVKTTVDDILSHGFEPLA
SIO_010081: YPL067C
subclass of: SO_0000673
so part of: YPL067C
location: complement(425251..425847)
location: region:425251-425847:-1
so has part: feature:425251-425847:-1:exon

NP_015258.1
type: Protein
SIO_000068: ncbiprotein

S000005988
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:425251-425847:-1:exon

YPL066W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RGL1
locus tag: YPL066W
so part of: sequence
location: <426233..>427672
location: region:426233-427672:1
so has part: feature:426233-427672:1:exon
subclass of: SO_0000010

856039
type: Gene
SIO_000068: ncbigene

position:426233:1
position: 426233
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:427672:1
position: 427672
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:426233-427672:1:exon

YPL066W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RGL1
locus tag: YPL066W
product: Rgl1p
transcript id: NM_001183880.1
SIO_010081: YPL066W
subclass of: SO_0000673
so part of: YPL066W
location: <426233..>427672
location: region:426233-427672:1
so has part: feature:426233-427672:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:426233-427672:1:exon

YPL066W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RGL1
locus tag: YPL066W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0097271 protein localization to bud neck [PMID:22344253]
experiment: EXISTENCE:physical interaction:GO:0097271 protein localization to bud neck [PMID:22344253]
note: Regulator of Rho1p signaling, cofactor of Tus1p; required for the localization of Tus1p during all phases of cytokinesis; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source
codon start: 1
product: Rgl1p
translation: MTHPVISLKPSYNSVIRGCPGLPDTLPRIECQLRVRSNNSLPFKLVKIEIVLKTIEIYFNKNLYSSNNSSFTPFNRPSDPSNGHSDTSNQNISIHYKKNIVLSHPTHDGDDLNNDLIGIDIPLTIGLPDDIKETNYNPKFGKTQTFLDCTVFYTEVGGGSSNKKRNFLYPVNVERYTYLPSPSYFRPINRSNITSPDQKFLISYSIENPCVSMNNDTLKLSISIRLNPFPNNATTPSSNDFDVSTPTLFSTKKKFKSKLKLKSITTQILEYLEILKNQSEFSSTQTTNILQTSVRQVDQIISMNSMIFQFNLKIFTKDKILQSFRSSESSCPETKVLINKIDDIPLQYHSSITTIGQHFNVSHYLSIRFKFNKSLKNFEINHPLIISFWSVSQLPLIENLILQERQTAKFAKKFYKNFGRIKNTSNNNNSSNCLEYPSLPPIIYNFNDPETNNRFNILYSQKDPSRTDPSKLRRVPVIQ
SIO_010081: YPL066W
subclass of: SO_0000673
so part of: YPL066W
location: 426233..427672
location: region:426233-427672:1
so has part: feature:426233-427672:1:exon

NP_015259.1
type: Protein
SIO_000068: ncbiprotein

S000005987
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:426233-427672:1:exon

YPL065W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: VPL13
alternative label: VPT28
gene: VPS28
locus tag: YPL065W
gene synonym: VPL13; VPT28
so part of: sequence
location: <427927..>428655
location: region:427927-428655:1
so has part: feature:427927-428655:1:exon
subclass of: SO_0000010

856040
type: Gene
SIO_000068: ncbigene

position:427927:1
position: 427927
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:428655:1
position: 428655
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:427927-428655:1:exon

YPL065W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: VPL13
alternative label: VPT28
gene: VPS28
locus tag: YPL065W
gene synonym: VPL13; VPT28
product: ESCRT-I subunit protein VPS28
transcript id: NM_001183879.1
SIO_010081: YPL065W
subclass of: SO_0000673
so part of: YPL065W
location: <427927..>428655
location: region:427927-428655:1
so has part: feature:427927-428655:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:427927-428655:1:exon

YPL065W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: VPL13
alternative label: VPT28
gene: VPS28
locus tag: YPL065W
gene synonym: VPL13; VPT28
experiment: EXISTENCE:curator inference:GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:15086794]
experiment: EXISTENCE:direct assay:GO:0000813 ESCRT I complex [PMID:15044434]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:11511343]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:17215868]
experiment: EXISTENCE:mutant phenotype:GO:0006612 protein targeting to membrane [PMID:11511343]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:11511343]
experiment: EXISTENCE:mutant phenotype:GO:1904669 ATP export [PMID:26585826]
experiment: EXISTENCE:physical interaction:GO:0000813 ESCRT I complex [PMID:16615894|PMID:11511343]
experiment: EXISTENCE:physical interaction:GO:0044877 protein-containing complex binding [PMID:17215868]
note: Component of the ESCRT-I complex; complex is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p; other members include Stp22p, Srn2p, Vps28p, and Mvb12p
codon start: 1
product: ESCRT-I subunit protein VPS28
translation: MQKHNIKLNQNQDISQLFHDEVPLFDNSITSKDKEVIETLSEIYSIVITLDHVEKAYLKDSIDDTQYTNTVDKLLKQFKVYLNSQNKEEINKHFQSIEAFCDTYNITASNAITRLERGIPITAEHAISTTTSAPSGDNKQSSSSDKKFNAKYVAEATGNFITVMDALKLNYNAKDQLHPLLAELLISINRVTRDDFENRSKLIDWIVRINKLSIGDTLTETQIRELLFDLELAYKSFYALLD
SIO_010081: YPL065W
subclass of: SO_0000673
so part of: YPL065W
location: 427927..428655
location: region:427927-428655:1
so has part: feature:427927-428655:1:exon

NP_015260.1
type: Protein
SIO_000068: ncbiprotein

S000005986
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:427927-428655:1:exon

YPL064C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CWC27
locus tag: YPL064C
so part of: sequence
location: complement(<428711..>429616)
location: region:428711-429616:-1
so has part: feature:428711-429616:-1:exon
subclass of: SO_0000010

856041
type: Gene
SIO_000068: ncbigene

position:428711:-1
position: 428711
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:429616:-1
position: 429616
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:428711-429616:-1:exon

YPL064C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CWC27
locus tag: YPL064C
product: putative peptidylprolyl isomerase CWC27
transcript id: NM_001183878.1
SIO_010081: YPL064C
subclass of: SO_0000673
so part of: YPL064C
location: complement(<428711..>429616)
location: region:428711-429616:-1
so has part: feature:428711-429616:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:428711-429616:-1:exon

YPL064C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CWC27
locus tag: YPL064C
EC number: 5.2.1.8
experiment: EXISTENCE:direct assay:GO:0005684 U2-type spliceosomal complex [PMID:11884590]
note: Component of a complex containing Cef1p; putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p; protein abundance increases in response to DNA replication stress
codon start: 1
product: putative peptidylprolyl isomerase CWC27
translation: MSSNIEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKPTQWLMFNANSTGEYRTVAEEKNPRIRFNRDGLLGWDRRRNTWFITVLADSKHVLNDCNVFGKIVGKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAKKLVKSAKVKMVYEDEQEDDDGDVQKLKPRKRMILPAWIKDDSRSEGIKLDASLDQPQEALIREKTELHDNVDEATTKETESQENIKEEPMDKRERETLAMLSKFQERIKNKNILK
SIO_010081: YPL064C
subclass of: SO_0000673
so part of: YPL064C
location: complement(428711..429616)
location: region:428711-429616:-1
so has part: feature:428711-429616:-1:exon

NP_015261.1
type: Protein
SIO_000068: ncbiprotein

S000005985
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:428711-429616:-1:exon

YPL063W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TIM50
locus tag: YPL063W
so part of: sequence
location: <429939..>431369
location: region:429939-431369:1
so has part: feature:429939-431369:1:exon
subclass of: SO_0000010

856042
type: Gene
SIO_000068: ncbigene

position:429939:1
position: 429939
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:431369:1
position: 431369
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:429939-431369:1:exon

YPL063W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TIM50
locus tag: YPL063W
product: protein translocase subunit TIM50
transcript id: NM_001183877.1
SIO_010081: YPL063W
subclass of: SO_0000673
so part of: YPL063W
location: <429939..>431369
location: region:429939-431369:1
so has part: feature:429939-431369:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:429939-431369:1:exon

YPL063W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TIM50
locus tag: YPL063W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005744 TIM23 mitochondrial import inner membrane translocase complex [PMID:12437925|PMID:12437924]
experiment: EXISTENCE:direct assay:GO:0030943 mitochondrion targeting sequence binding [PMID:18418384|PMID:19144822]
experiment: EXISTENCE:direct assay:GO:0046902 regulation of mitochondrial membrane permeability [PMID:16763150]
experiment: EXISTENCE:mutant phenotype:GO:0008320 protein transmembrane transporter activity [PMID:16763150]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:12437924|PMID:12437925]
note: Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel
codon start: 1
product: protein translocase subunit TIM50
translation: MLSILRNSVRLNSRALRVVPSAANTLTSVQASRRLLTSYSSFLQKETKDDKPKSILTDDMLFKAGVDVDEKGQGKNEETSGEGGEDKNEPSSKSEKSRRKRQTSTDIKREKYANWFYIFSLSALTGTAIYMARDWEPQESEELKKDIDNGYTLSLMYKRFKARFNSMFTYFQEPPFPDLLPPPPPPPYQRPLTLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADDKLVRLIPFLEYLATQQTKDVRPILNSFEDKKNLAEEFDHRVKKLKDKFYGDHKSGGNWAMTALGLGNSLGGSTKFPLDLIHEEGQKNYLMFMKMIEEEKEKIRIQQEQMGGQTFTLKDYVEGNLPSPEEQMKIQLEKQKEVDALFEEEKKKKKIAESK
SIO_010081: YPL063W
subclass of: SO_0000673
so part of: YPL063W
location: 429939..431369
location: region:429939-431369:1
so has part: feature:429939-431369:1:exon

NP_015262.1
type: Protein
SIO_000068: ncbiprotein

S000005984
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:429939-431369:1:exon

YPL062W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL062W
so part of: sequence
location: <431895..>432299
location: region:431895-432299:1
so has part: feature:431895-432299:1:exon
subclass of: SO_0000010

856043
type: Gene
SIO_000068: ncbigene

position:431895:1
position: 431895
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:432299:1
position: 432299
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:431895-432299:1:exon

YPL062W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL062W
product: uncharacterized protein
transcript id: NM_001348885.1
SIO_010081: YPL062W
subclass of: SO_0000673
so part of: YPL062W
location: <431895..>432299
location: region:431895-432299:1
so has part: feature:431895-432299:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:431895-432299:1:exon

YPL062W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL062W
experiment: EXISTENCE:mutant phenotype:GO:0032443 regulation of ergosterol biosynthetic process [PMID:30683746]
experiment: EXISTENCE:mutant phenotype:GO:0051485 terpenoid biosynthetic process, mevalonate-dependent [PMID:30683746]
experiment: EXISTENCE:mutant phenotype:GO:1904182 regulation of pyruvate dehydrogenase activity [PMID:30683746]
note: hypothetical protein; conserved across S. cerevisiae strains; deletion decreases transcription of downstream gene ALD6; YPL062W is not an essential gene; null mutant shows decrease in terpenoid production; homozygous diploid mutant shows a decrease in glycogen accumulation
codon start: 1
product: uncharacterized protein
translation: MIELDYVKGEDTIVEATSTSPWLMRSPLARAAEKRGSGLFFDINEGHGQHRDVIVAYGVSKPKRRSPHPHGNKAADKRKTTEKEPERKKRVGAPRTCKKICIQLLYRFNFTVLGIGNVCNIDLLLGTVSATNAI
SIO_010081: YPL062W
subclass of: SO_0000673
so part of: YPL062W
location: 431895..432299
location: region:431895-432299:1
so has part: feature:431895-432299:1:exon

NP_001335823.1
type: Protein
SIO_000068: ncbiprotein

S000005983
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:431895-432299:1:exon

YPL061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALD1
gene: ALD6
locus tag: YPL061W
gene synonym: ALD1
so part of: sequence
location: <432588..>434090
location: region:432588-434090:1
so has part: feature:432588-434090:1:exon
subclass of: SO_0000010

856044
type: Gene
SIO_000068: ncbigene

position:432588:1
position: 432588
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:434090:1
position: 434090
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:432588-434090:1:exon

YPL061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALD1
gene: ALD6
locus tag: YPL061W
gene synonym: ALD1
product: aldehyde dehydrogenase (NADP(+)) ALD6
transcript id: NM_001183875.1
SIO_010081: YPL061W
subclass of: SO_0000673
so part of: YPL061W
location: <432588..>434090
location: region:432588-434090:1
so has part: feature:432588-434090:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:432588-434090:1:exon

YPL061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALD1
gene: ALD6
locus tag: YPL061W
gene synonym: ALD1
EC number: 1.2.1.4
experiment: EXISTENCE:direct assay:GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity [PMID:9473035]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16806052|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:16806052]
experiment: EXISTENCE:genetic interaction:GO:0006740 NADPH regeneration [PMID:12584194]
experiment: EXISTENCE:mutant phenotype:GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity [PMID:9392076]
experiment: EXISTENCE:mutant phenotype:GO:0005829 cytosol [PMID:9392076]
experiment: EXISTENCE:mutant phenotype:GO:0009651 response to salt stress [PMID:15146068]
experiment: EXISTENCE:mutant phenotype:GO:0019413 acetate biosynthetic process [PMID:11870853]
note: Cytosolic aldehyde dehydrogenase; activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress
codon start: 1
product: aldehyde dehydrogenase (NADP(+)) ALD6
translation: MTKLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL
SIO_010081: YPL061W
subclass of: SO_0000673
so part of: YPL061W
location: 432588..434090
location: region:432588-434090:1
so has part: feature:432588-434090:1:exon

NP_015264.1
type: Protein
SIO_000068: ncbiprotein

S000005982
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:432588-434090:1:exon

YPL060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPE10
gene: MFM1
locus tag: YPL060W
gene synonym: LPE10
so part of: sequence
location: <434523..>435764
location: region:434523-435764:1
so has part: feature:434523-435764:1:exon
subclass of: SO_0000010

856045
type: Gene
SIO_000068: ncbigene

position:434523:1
position: 434523
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:435764:1
position: 435764
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:434523-435764:1:exon

YPL060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPE10
gene: MFM1
locus tag: YPL060W
gene synonym: LPE10
product: Mfm1p
transcript id: NM_001183874.1
SIO_010081: YPL060W
subclass of: SO_0000673
so part of: YPL060W
location: <434523..>435764
location: region:434523-435764:1
so has part: feature:434523-435764:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:434523-435764:1:exon

YPL060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPE10
gene: MFM1
locus tag: YPL060W
gene synonym: LPE10
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:11254124]
experiment: EXISTENCE:mutant phenotype:GO:0015095 magnesium ion transmembrane transporter activity [PMID:11254124]
experiment: EXISTENCE:mutant phenotype:GO:0045016 mitochondrial magnesium ion transmembrane transport [PMID:11254124]
note: Mitochondrial inner membrane magnesium transporter; involved in maintenance of mitochondrial magnesium concentrations and membrane potential; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p
codon start: 1
product: Mfm1p
translation: MRAFPRVLPFRHQRSYNNILLRTVRLFGSSLSSFDFSRQMPKVDPDNTAAMLLQKNLIQRNNMLYGYGSGTIRCTLLDSTGRAKSPLVEIKREDLVSKHGLLPRDLRKIEKSRKNDLVPSLLVRENSILISLLTVKALIKPDMVIIFDSAGSGITLNSEAHKDFINDMKLRLKNQETSELNSDPLPYEFRALETIFISALSNLTSEMKVLLTICKGVLQDLEFSITRDKLRFLLGQNKKLSSFNKKAVLVKDMLDDLLEQDDMLCDMYLTDKKAGKIRVQDDHTEIEMLLETYHNYVDEIVQKSESAISDVKTTEEIINIILDSNRNELMLLGIRYAIGMLSLGGALFLGSIYGMNLESFIEESNYAYLTVTILGLISTVWLYAKGIRHLHKLQRMTLLSKIKTDSVHELLKK
SIO_010081: YPL060W
subclass of: SO_0000673
so part of: YPL060W
location: 434523..435764
location: region:434523-435764:1
so has part: feature:434523-435764:1:exon

NP_015265.1
type: Protein
SIO_000068: ncbiprotein

S000005981
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:434523-435764:1:exon

YNCP0007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0007C
so part of: sequence
location: complement(435893..435964)
location: region:435893-435964:-1
so has part: feature:435893-435964:-1:exon
subclass of: SO_0000663

856046
type: Gene
SIO_000068: ncbigene

position:435893:-1
position: 435893
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:435964:-1
position: 435964
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:435893-435964:-1:exon

YNCP0007C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0007C
product: tRNA-Cys
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Cysteine tRNA (tRNA-Cys), predicted by tRNAscan-SE analysis
SIO_010081: YNCP0007C
subclass of: SO_0000673
so part of: YNCP0007C
location: complement(435893..435964)
location: region:435893-435964:-1
so has part: feature:435893-435964:-1:exon

S000006528
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:435893-435964:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 436068..436249
location: region:436068-436249:1
so has part: feature:436068-436249:1:region

S000007196
type: SGD
SIO_000068: sgd

position:436068:1
position: 436068
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:436249:1
position: 436249
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436068-436249:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(436250..436587)
location: region:436250-436587:-1
so has part: feature:436250-436587:-1:region

S000007185
type: SGD
SIO_000068: sgd

position:436250:-1
position: 436250
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:436587:-1
position: 436587
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436250-436587:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 436594..436731
location: region:436594-436731:1
so has part: feature:436594-436731:1:region

S000007197
type: SGD
SIO_000068: sgd

position:436594:1
position: 436594
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:436731:1
position: 436731
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436594-436731:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YPLCTy4-1; Ty4 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YPLCTy4-1
so part of: sequence
location: complement(436890..443112)
location: region:436890-443112:-1
so has part: feature:436890-443112:-1:region

S000007188
type: SGD
SIO_000068: sgd

position:436890:-1
position: 436890
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:443112:-1
position: 443112
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436890-443112:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(436890..437260)
location: region:436890-437260:-1
so has part: feature:436890-437260:-1:region

S000007186
type: SGD
SIO_000068: sgd

position:437260:-1
position: 437260
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436890-437260:-1:region

YPL060C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL060C-A
so part of: sequence
location: complement(<437333..>442742)
location: region:437333-442742:-1
so has part: feature:437333-442742:-1:exon
subclass of: SO_0000010

856047
type: Gene
SIO_000068: ncbigene

position:437333:-1
position: 437333
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:442742:-1
position: 442742
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:437333-442742:-1:exon

YPL060C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL060C-A
product: gag-pol fusion protein
transcript id: NM_001305015.2
SIO_010081: YPL060C-A
subclass of: SO_0000673
so part of: YPL060C-A
location: complement(<437333..>442742)
location: region:437333-442742:-1
so has part: feature:437333-442742:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:437333-442742:-1:exon

YPL060C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL060C-A
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
ribosomal slippage: true
note: TyA Gag protein; the main structural constituent of virus-like particles (VLPs); Gag processing produces capsid proteins
codon start: 1
product: gag-pol fusion protein
translation: MATPVRDETRNVIDDNISARIQSKVKTNDTVRQTPSSLRKVSIKDEQVKQYQRNLNRFKTILNGLKAEEEKLSETDDIQMLAEKLLKLGETIDKVENRIVDLVEKIQLLETNENNNILHEHIDATGTYYLFDTLTSTNKRFYPKDCVFDYRTNNVENIPILLNNFKKFIKKYQFDDVFENDIIEIDPRENEILCKIIKEGLGESLDIMNTNTTDIFRIIDGLKNKYRSLHGRDVRIRAWEKVLVDTTCRNSALLMNKLQKLVLMEKWIFSKCCQDCPNLKDYLQEAIMGTLHESLRNSVKQRLYNIPHNVGINHEEFLINTVIETVIDLSPIADDQIENSCMYCKSVFHCSINCKKKPNRELRPDSTNFSKTYYLQGAQRQQQLKSSAKEQKSWNKTQKKSNKVYNSKKLVIIDTGSGVNITNDKTLLHNYEDSNRSTRFFGIGKNSSVSVKGYGYIKIKNGHNNTDNKCLLTYYVPEEESTIISCYDLAKKTKMVLSRKYTRLGNKIIKIKTKIVNGVIHVKMNELIERPSDDSKINAIKPTSSPGFKLNKRSITLEDAHKRMGHTGIQQIENSIKHNHYEESLDLIKEPNEFWCQTCKISKATKRNHYTGSMNNHSTDHEPGSSWCMDIFGPVSSSNADTKRYMLIMVDNNTRYCMTSTHFNKNAETILAQIRKNIQYVETQFDRKVREINSDRGTEFTNDQIEEYFISKGIHHILTSTQDHAANGRAERYIRTIVTDATTLLRQSNLRVKFWEYAVTSATNIRNCLEHKSTGKLPLKAISRQPVTVRLMSFLPFGEKGIIWNHNHKKLKPSGLPSIILCKDPNSYGYKFFIPSKNKIVTSDNYTIPNYTMDGRVRNTQNIYKSHQFSSHNDNEEDQIETVTNLCEALENYEDDNKPITRLEDLFTEEELSQIDSNAKYPSPSNNLEGDLDYVFSDVEESGDYDVESELSTTNTSISTDKNKILSNKDFNSELASTEISISEIDKKGLINTSHIDEDKYDEKVHRIPSIIQEKLVGSKNTIKINDENRISDRIRSKNIGSILNTGLSRCVDITDESITNKDESMHNAKPELIQEQFNKTNHETSFPKEGSIGTKCKIPKYRQWISLKTGDTSLPIKTLESINNHHSNDYSTNKVEKFEKENHHPPPIEDIVDMSDQTDMESNCQDGNNLKELKVTDKNVPTDNGTNVSPRLEQNIEASGSPVQTVNKSAFLNKEFSSLNMKRKRKRHDKNNSLTSYELERDKKRSKRNRVKLIPDNMETVSAQKIRAIYYNEAISKNPDLKEKHEYKQAYHKELQNLKDMKVFDVDVKYSRSEIPDNLIVPTNTIFTKKRNGIYKARIVCRGDTQSPDTYSVITTESLNHNHIKIFLMIANNRNMFMKTLDINHAFLYAKLEEEIYIPHPHDRRCVVKLNKALYGLKQSPKEWNDHLRQYLNGIGLKDNSYTPGLYQTEDKNLMIAVYVDDCVIAASNEQRLDEFINKLKSNFELKITGTLIDDVLDTDILGMDLVYNKRLGTIDLTLKSFINRMDKKYNEELKKIRKSSIPHMSTYKIDPKKDVLQMSEEEFRQGVLKLQQLLGELNYVRHKCRYDINFAVKKVARLVNYPHERVFYMIYKIIQYLVRYKDIGIHYDRDCNKDKKVIAITDASVGSEYDAQSRIGVILWYGMNIFNVYSNKSTNRCVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQGLNRSYQQPKEKFTWIKTEIIKEKIKEKSIKLLKITGKGNIADLLTKPVSASDFKRFIQVLKNKITSQDILASTDY
SIO_010081: YPL060C-A
subclass of: SO_0000673
so part of: YPL060C-A
location: complement(join(437333..439427,439429..442742))
location: region:437333-442742:-1
so has part: feature:439429-442742:-1:exon
so has part: feature:437333-439427:-1:exon

NP_001291944.1
type: Protein
SIO_000068: ncbiprotein

S000007388
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:439429-442742:-1:exon

position:439429:-1
position: 439429
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:437333-439427:-1:exon

position:439427:-1
position: 439427
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(442742..443112)
location: region:442742-443112:-1
so has part: feature:442742-443112:-1:region

S000007187
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:442742-443112:-1:region

YPL059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GRX5
locus tag: YPL059W
so part of: sequence
location: <444579..>445031
location: region:444579-445031:1
so has part: feature:444579-445031:1:exon
subclass of: SO_0000010

856048
type: Gene
SIO_000068: ncbigene

position:444579:1
position: 444579
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:445031:1
position: 445031
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:444579-445031:1:exon

YPL059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GRX5
locus tag: YPL059W
product: monothiol glutaredoxin GRX5
transcript id: NM_001183873.1
SIO_010081: YPL059W
subclass of: SO_0000673
so part of: YPL059W
location: <444579..>445031
location: region:444579-445031:1
so has part: feature:444579-445031:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:444579-445031:1:exon

YPL059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GRX5
locus tag: YPL059W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:11950925|PMID:15456753]
experiment: EXISTENCE:direct assay:GO:0015036 disulfide oxidoreductase activity [PMID:12730244]
experiment: EXISTENCE:direct assay:GO:0051537 2 iron, 2 sulfur cluster binding [PMID:23615440]
experiment: EXISTENCE:genetic interaction:GO:0097428 protein maturation by iron-sulfur cluster transfer [PMID:11950925]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:10567543]
experiment: EXISTENCE:mutant phenotype:GO:0015036 disulfide oxidoreductase activity [PMID:10567543]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:10567543]
experiment: EXISTENCE:mutant phenotype:GO:0097428 protein maturation by iron-sulfur cluster transfer [PMID:11950925|PMID:12970193]
experiment: EXISTENCE:mutant phenotype:GO:0106034 protein maturation by [2Fe-2S] cluster transfer [PMID:23615440]
experiment: EXISTENCE:mutant phenotype:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:23615440]
note: Glutathione-dependent oxidoreductase; mitochondrial matrix protein involved at an early step in the biogenesis of iron-sulfur centers along with Bol1p; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p
codon start: 1
product: monothiol glutaredoxin GRX5
translation: MFLPKFNPIRSFSPILRAKTLLRYQNRMYLSTEIRKAIEDAIESAPVVLFMKGTPEFPKCGFSRATIGLLGNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELADLLEEAQALVPEEEEETKDR
SIO_010081: YPL059W
subclass of: SO_0000673
so part of: YPL059W
location: 444579..445031
location: region:444579-445031:1
so has part: feature:444579-445031:1:exon

NP_015266.1
type: Protein
SIO_000068: ncbiprotein

S000005980
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:444579-445031:1:exon

YPL058C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PDR12
locus tag: YPL058C
so part of: sequence
location: complement(<445842..>450377)
location: region:445842-450377:-1
so has part: feature:445842-450377:-1:exon
subclass of: SO_0000010

856049
type: Gene
SIO_000068: ncbigene

position:445842:-1
position: 445842
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:450377:-1
position: 450377
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:445842-450377:-1:exon

YPL058C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PDR12
locus tag: YPL058C
product: ATP-binding cassette multidrug transporter PDR12
transcript id: NM_001183872.1
SIO_010081: YPL058C
subclass of: SO_0000673
so part of: YPL058C
location: complement(<445842..>450377)
location: region:445842-450377:-1
so has part: feature:445842-450377:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:445842-450377:-1:exon

YPL058C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PDR12
locus tag: YPL058C
experiment: EXISTENCE:direct assay:GO:0005342 organic acid transmembrane transporter activity [PMID:10419965]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:9687494]
experiment: EXISTENCE:direct assay:GO:0015849 organic acid transport [PMID:10419965]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity
codon start: 1
product: ATP-binding cassette multidrug transporter PDR12
translation: MSSTDEHIEKDISSRSNHDDDYANSVQSYAASEGQVDNEDLAATSQLSRHLSNILSNEEGIERLESMARVISHKTKKEMDSFEINDLDFDLRSLLHYLRSRQLEQGIEPGDSGIAFKNLTAVGVDASAAYGPSVEEMFRNIASIPAHLISKFTKKSDVPLRNIIQNCTGVVESGEMLFVVGRPGAGCSTFLKCLSGETSELVDVQGEFSYDGLDQSEMMSKYKGYVIYCPELDFHFPKITVKETIDFALKCKTPRVRIDKMTRKQYVDNIRDMWCTVFGLRHTYATKVGNDFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRGLDASTALEFAQAIRTATNMVNNSAIVAIYQAGENIYELFDKTTVLYNGRQIYFGPADKAVGYFQRMGWVKPNRMTSAEFLTSVTVDFENRTLDIKPGYEDKVPKSSSEFEEYWLNSEDYQELLRTYDDYQSRHPVNETRDRLDVAKKQRLQQGQRENSQYVVNYWTQVYYCMIRGFQRVKGDSTYTKVYLSSFLIKALIIGSMFHKIDDKSQSTTAGAYSRGGMLFYVLLFASVTSLAEIGNSFSSRPVIVKHKSYSMYHLSAESLQEIITEFPTKFVAIVILCLITYWIPFMKYEAGAFFQYILYLLTVQQCTSFIFKFVATMSKSGVDAHAVGGLWVLMLCVYAGFVLPIGEMHHWIRWLHFINPLTYAFESLVSTEFHHREMLCSALVPSGPGYEGISIANQVCDAAGAVKGNLYVSGDSYILHQYHFAYKHAWRNWGVNIVWTFGYIVFNVILSEYLKPVEGGGDLLLYKRGHMPELGTENADARTASREEMMEALNGPNVDLEKVIAEKDVFTWNHLDYTIPYDGATRKLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPASFNRSCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEYILNCIGAGATASVNSDWHDLWLASPECAAARAEVEELHRTLPGRAVNDDPELATRFAASYMTQIKCVLRRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGGAIEAFSSIFMLLLIALAMINQLHVFAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFMCFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMINSNLFAAMLLFCGILQPREKMPAFWRRLMYNVSPFTYVVQALVTPLVHNKKVVCNPHEYNIMDPPSGKTCGEFLSTYMDNNTGYLVNPTATENCQYCPYTVQDQVVAKYNVKWDHRWRNFGFMWAYICFNIAAMLICYYVVRVKVWSLKSVLNFKKWFNGPRKERHEKDTNIFQTVPGDENKITKK
SIO_010081: YPL058C
subclass of: SO_0000673
so part of: YPL058C
location: complement(445842..450377)
location: region:445842-450377:-1
so has part: feature:445842-450377:-1:exon

NP_015267.1
type: Protein
SIO_000068: ncbiprotein

S000005979
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:445842-450377:-1:exon

YPL057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BCL21
alternative label: CSG1
alternative label: LPE15
gene: SUR1
locus tag: YPL057C
gene synonym: BCL21; CSG1; LPE15
so part of: sequence
location: complement(<451909..>453057)
location: region:451909-453057:-1
so has part: feature:451909-453057:-1:exon
subclass of: SO_0000010

856050
type: Gene
SIO_000068: ncbigene

position:451909:-1
position: 451909
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:453057:-1
position: 453057
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:451909-453057:-1:exon

YPL057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BCL21
alternative label: CSG1
alternative label: LPE15
gene: SUR1
locus tag: YPL057C
gene synonym: BCL21; CSG1; LPE15
product: mannosylinositol phosphorylceramide synthase catalytic subunit SUR1
transcript id: NM_001183871.1
SIO_010081: YPL057C
subclass of: SO_0000673
so part of: YPL057C
location: complement(<451909..>453057)
location: region:451909-453057:-1
so has part: feature:451909-453057:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:451909-453057:-1:exon

YPL057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BCL21
alternative label: CSG1
alternative label: LPE15
gene: SUR1
locus tag: YPL057C
gene synonym: BCL21; CSG1; LPE15
EC number: 2.4.1.370
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19001347]
experiment: EXISTENCE:mutant phenotype:GO:0006675 mannosyl-inositol phosphorylceramide metabolic process [PMID:9323360]
experiment: EXISTENCE:mutant phenotype:GO:0006688 glycosphingolipid biosynthetic process [PMID:9323360]
experiment: EXISTENCE:mutant phenotype:GO:0030148 sphingolipid biosynthetic process [PMID:12954640]
experiment: EXISTENCE:mutant phenotype:GO:0103064 inositol phosphorylceramide mannosyltransferase activity [PMID:12954640]
note: Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p; SUR1 has a paralog, CSH1, that arose from the whole genome duplication
codon start: 1
product: mannosylinositol phosphorylceramide synthase catalytic subunit SUR1
translation: MRKELKYLICFNILLLLSIIYYTFDLLTLCIDDTVKDAILEEDLNPDAPPKPQLIPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYGGVYIDLDDGCERKLDPLLAFPAFLRKTSPLGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKRWRIPKNGTVRILQPAYYKMHSYSFFSITKGSSWHLDDAKLMKALENHILSCVVTGFIFGFFILYGEFTFYCWLCSKNFSNLTKNWKLNAIKVRFVTILNSLGLRLKLSKSTSDTASATLLARQQKRLRKDSNTNIVLLKSSRKSDVYDLEKNDSSKYSLGNNSS
SIO_010081: YPL057C
subclass of: SO_0000673
so part of: YPL057C
location: complement(451909..453057)
location: region:451909-453057:-1
so has part: feature:451909-453057:-1:exon

NP_015268.1
type: Protein
SIO_000068: ncbiprotein

S000005978
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:451909-453057:-1:exon

YPL056C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LCL1
locus tag: YPL056C
so part of: sequence
location: complement(<453430..>453735)
location: region:453430-453735:-1
so has part: feature:453430-453735:-1:exon
subclass of: SO_0000010

856051
type: Gene
SIO_000068: ncbigene

position:453430:-1
position: 453430
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:453735:-1
position: 453735
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:453430-453735:-1:exon

YPL056C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LCL1
locus tag: YPL056C
product: Lcl1p
transcript id: NM_001183870.1
SIO_010081: YPL056C
subclass of: SO_0000673
so part of: YPL056C
location: complement(<453430..>453735)
location: region:453430-453735:-1
so has part: feature:453430-453735:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:453430-453735:-1:exon

YPL056C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LCL1
locus tag: YPL056C
note: hypothetical protein; deletion mutant is fluconazole resistant and has long chronological lifespan
codon start: 1
product: Lcl1p
translation: MKNAALCEALPLLATCSHEIPPTPHTVCFVFPPALLLSPSKLTLLNSRRVASRCVIIIDPRLLRLFSCSRPQQLPRDKNQSFAKPSFSFFFFLLTSLLSPF
SIO_010081: YPL056C
subclass of: SO_0000673
so part of: YPL056C
location: complement(453430..453735)
location: region:453430-453735:-1
so has part: feature:453430-453735:-1:exon

NP_015269.1
type: Protein
SIO_000068: ncbiprotein

S000005977
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:453430-453735:-1:exon

YPL055C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LGE1
locus tag: YPL055C
so part of: sequence
location: complement(<453992..>454990)
location: region:453992-454990:-1
so has part: feature:453992-454990:-1:exon
subclass of: SO_0000010

856052
type: Gene
SIO_000068: ncbigene

position:453992:-1
position: 453992
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:454990:-1
position: 454990
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:453992-454990:-1:exon

YPL055C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LGE1
locus tag: YPL055C
product: Lge1p
transcript id: NM_001183869.1
SIO_010081: YPL055C
subclass of: SO_0000673
so part of: YPL055C
location: complement(<453992..>454990)
location: region:453992-454990:-1
so has part: feature:453992-454990:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:453992-454990:-1:exon

YPL055C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LGE1
locus tag: YPL055C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15528187|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006279 premeiotic DNA replication [PMID:18069899]
experiment: EXISTENCE:mutant phenotype:GO:0006513 protein monoubiquitination [PMID:12535538]
experiment: EXISTENCE:mutant phenotype:GO:0008361 regulation of cell size [PMID:12089449]
experiment: EXISTENCE:mutant phenotype:GO:0016571 histone methylation [PMID:12535538]
experiment: EXISTENCE:mutant phenotype:GO:0016574 histone ubiquitination [PMID:12535538]
note: Protein involved in histone H2B ubiquitination; acts as cofactor for Bre1p; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division
codon start: 1
product: Lge1p
translation: MSGYTGNNYSRYSSTPPRQRGGYHHARRSRGGAGGSYYRGGNASYGARYNSDYEQPPQEGDLRQTGAYYRNGYTDTRPYYSANSRHYQAQPSPRYNNGTNSYHLPQRGNSQDTNGRTTSASQEDNDEKRVKSRYRNMQADHPRQQPMSVGSTSSRNGSSGNSSTSSTSNGLPPPPSVSSITNNRSYHSSAYPYSSSHTYNNYHHRETPPPPPSNGYYAKGYPVHVPENRSNSDGSSSSVVKKKRILDMKDSPFIYLTDFDKNVKKTNNTESECEKAREVFKESDSIDSALEELNLKINSNELELRLLNNQCDKHALNIQLTQEKLDSLLLMQ
SIO_010081: YPL055C
subclass of: SO_0000673
so part of: YPL055C
location: complement(453992..454990)
location: region:453992-454990:-1
so has part: feature:453992-454990:-1:exon

NP_015270.1
type: Protein
SIO_000068: ncbiprotein

S000005976
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:453992-454990:-1:exon

YPL054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LEE1
locus tag: YPL054W
so part of: sequence
location: <455759..>456664
location: region:455759-456664:1
so has part: feature:455759-456664:1:exon
subclass of: SO_0000010

856053
type: Gene
SIO_000068: ncbigene

position:455759:1
position: 455759
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:456664:1
position: 456664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:455759-456664:1:exon

YPL054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LEE1
locus tag: YPL054W
product: Lee1p
transcript id: NM_001183868.1
SIO_010081: YPL054W
subclass of: SO_0000673
so part of: YPL054W
location: <455759..>456664
location: region:455759-456664:1
so has part: feature:455759-456664:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:455759-456664:1:exon

YPL054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LEE1
locus tag: YPL054W
note: Zinc-finger hypothetical protein
codon start: 1
product: Lee1p
translation: MDAFENMSVSNHPGGNARRNSQSANEMLASQIQDFQNIPRSFNDSNANVNLSKNCTVGNQLPFSSRQQKIIMEHLLITKNNSQQQKDYSHVPCKFFKMGNCQAGSSCPFSHSPDIISSANNLPCKYFAKGNCKFGNKCVNAHVLPNGFKMNSKEPIDITPPSQNNYLSHARSASFSTYTSPPLSAQTEFSHSASNANYFSSQYLMYSPQKSPEALYTEFFSPPSSSSSYINYSYNNSNINAYSPVSSSSSNIWQEQGQTTLSNPSVNQNLRYRTGPAIQEESDNEIEDLLIHNFNSRYCHE
SIO_010081: YPL054W
subclass of: SO_0000673
so part of: YPL054W
location: 455759..456664
location: region:455759-456664:1
so has part: feature:455759-456664:1:exon

NP_015271.1
type: Protein
SIO_000068: ncbiprotein

S000005975
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:455759-456664:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1633; Autonomously Replicating Sequence
so part of: sequence
location: 456563..456810
location: region:456563-456810:1
so has part: feature:456563-456810:1:region

S000119038
type: SGD
SIO_000068: sgd

position:456563:1
position: 456563
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:456810:1
position: 456810
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:456563-456810:1:region

YPL053C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MNN6
gene: KTR6
locus tag: YPL053C
gene synonym: MNN6
so part of: sequence
location: complement(<457118..>458458)
location: region:457118-458458:-1
so has part: feature:457118-458458:-1:exon
subclass of: SO_0000010

856054
type: Gene
SIO_000068: ncbigene

position:457118:-1
position: 457118
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:458458:-1
position: 458458
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:457118-458458:-1:exon

YPL053C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MNN6
gene: KTR6
locus tag: YPL053C
gene synonym: MNN6
product: putative mannosyltransferase
transcript id: NM_001183867.1
SIO_010081: YPL053C
subclass of: SO_0000673
so part of: YPL053C
location: complement(<457118..>458458)
location: region:457118-458458:-1
so has part: feature:457118-458458:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:457118-458458:-1:exon

YPL053C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MNN6
gene: KTR6
locus tag: YPL053C
gene synonym: MNN6
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:30842360]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:9218445]
experiment: EXISTENCE:mutant phenotype:GO:0000031 mannosylphosphate transferase activity [PMID:9218445]
experiment: EXISTENCE:mutant phenotype:GO:0006487 protein N-linked glycosylation [PMID:9218445]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:30842360]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:9090056]
note: Probable mannosylphosphate transferase; involved in the synthesis of core oligosaccharides in protein glycosylation pathway; facilitates the exit of Mnn4p from the ER via COPII-coated vesicles; member of the KRE2/MNT1 mannosyltransferase family; KTR6 has a paralog, KRE2, that arose from the whole genome duplication
codon start: 1
product: putative mannosyltransferase
translation: MHVLLSKKIARFLLISFVFVLALMVTINHPKTKQMSEQYVTPYLPKSLQPIAKISAEEQRRIQSEQEEAELKQSLEGEAIRNATVNAIKEKIKSYGGNETTLGFMVPSYINHRGSPPKACFVSLITERDSMTQILQSIDEVQVKFNKNFAYPWVFISQGELDGMKQEMIRQAITDSMNGDPELINIKFAEIPADEWVYPEWIDENKAAESLISLANVPDGDSRAVRYQARYFAGFFWRHPVLDEFDWYWRVDPGIKLYCDIDHDLFRWMQDEGKVFGFTLSMSEAKEANEKIWDVTKKFAKDFPKFISENNFKSFITKKDSEDFNNCEFTSNFEIGNLNFYRSPAYRKFFNYIDEEGGIFYWKWSDSIIHTIGLSMLLPKDKIHFFENIGFHYDKYNNCPLNDDIWNQYNCNCDQGNDFTFRSGSCGGHYFDIMKKDKPEGWDRLP
SIO_010081: YPL053C
subclass of: SO_0000673
so part of: YPL053C
location: complement(457118..458458)
location: region:457118-458458:-1
so has part: feature:457118-458458:-1:exon

NP_015272.1
type: Protein
SIO_000068: ncbiprotein

S000005974
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:457118-458458:-1:exon

YPL052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YPL052W-A
gene: OAZ1
locus tag: YPL052W
gene synonym: YPL052W-A
so part of: sequence
location: <458799..>459678
location: region:458799-459678:1
so has part: feature:458799-459678:1:exon
subclass of: SO_0000010

856055
type: Gene
SIO_000068: ncbigene

position:458799:1
position: 458799
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:459678:1
position: 459678
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:458799-459678:1:exon

YPL052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YPL052W-A
gene: OAZ1
locus tag: YPL052W
gene synonym: YPL052W-A
product: Oaz1p
transcript id: NM_001183866.4
SIO_010081: YPL052W
subclass of: SO_0000673
so part of: YPL052W
location: <458799..>459678
location: region:458799-459678:1
so has part: feature:458799-459678:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:458799-459678:1:exon

YPL052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YPL052W-A
gene: OAZ1
locus tag: YPL052W
gene synonym: YPL052W-A
experiment: EXISTENCE:curator inference:GO:0005737 cytoplasm [PMID:15538383]
experiment: EXISTENCE:direct assay:GO:0008073 ornithine decarboxylase inhibitor activity [PMID:15538383]
experiment: EXISTENCE:direct assay:GO:0061136 regulation of proteasomal protein catabolic process [PMID:18089576]
experiment: EXISTENCE:mutant phenotype:GO:2001125 negative regulation of translational frameshifting [PMID:21900894]
ribosomal slippage: true
note: Regulator of ornithine decarboxylase Spe1p; antizyme that binds to Spe1p to stimulate ubiquitin-independent degradation by the proteasome; binding of polyamines to nascent Oaz1p during translation stimulates +1 ribosomal frameshifting, allowing translation of full-length Oaz1p
codon start: 1
product: Oaz1p
translation: MYEVIQKRKTKIINVLQSPELMRLIEDPSNLGISLHFPVSSLLKSNKCTPMPKLSTYSLASGGFKDWCADIPLDVPPEIDIIDFYWDVILCMESQFILDYNVPSKNKGNNQKSVAKLLKNKLVNDMKTTLKRLIYNENTKQYKNNNSHDGYNWRKLGSQYFILYLPLFTQELIWCKLNENYFHVVLPSLLNSRNVHDNHSTYINKDWLLALLELTSNLNQNFKFEYMKLRLYILRDDLINNGLDLLKNLNWVGGKLIKNEDREVLLNSTDLATDSISHLLGDENFVILEFEC
SIO_010081: YPL052W
subclass of: SO_0000673
so part of: YPL052W
location: join(458799..459005,459007..459678)
location: region:458799-459678:1
so has part: feature:458799-459005:1:exon
so has part: feature:459007-459678:1:exon

NP_015273.2
type: Protein
SIO_000068: ncbiprotein

S000005973
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:458799-459005:1:exon

position:459005:1
position: 459005
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:459007-459678:1:exon

position:459007:1
position: 459007
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPL051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ARL3
locus tag: YPL051W
so part of: sequence
location: <459963..>460559
location: region:459963-460559:1
so has part: feature:459963-460559:1:exon
subclass of: SO_0000010

856056
type: Gene
SIO_000068: ncbigene

position:459963:1
position: 459963
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:460559:1
position: 460559
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:459963-460559:1:exon

YPL051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ARL3
locus tag: YPL051W
product: Arf family GTPase ARL3
transcript id: NM_001183865.1
SIO_010081: YPL051W
subclass of: SO_0000673
so part of: YPL051W
location: <459963..>460559
location: region:459963-460559:1
so has part: feature:459963-460559:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:459963-460559:1:exon

YPL051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ARL3
locus tag: YPL051W
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:9920936]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15077113|PMID:15077114]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:9920936]
experiment: EXISTENCE:mutant phenotype:GO:0006886 intracellular protein transport [PMID:9920936]
experiment: EXISTENCE:mutant phenotype:GO:0034067 protein localization to Golgi apparatus [PMID:26966233|PMID:12620189]
experiment: EXISTENCE:mutant phenotype:GO:0034976 response to endoplasmic reticulum stress [PMID:26966233]
experiment: EXISTENCE:mutant phenotype:GO:0043001 Golgi to plasma membrane protein transport [PMID:16926193]
note: ARF-like small GTPase of the RAS superfamily; required for recruitment of Arl1p, a GTPase that regulates membrane traffic, to the Golgi apparatus; NatC-catalyzed N-terminal acetylation regulates Golgi membrane association mediated by interaction with membrane receptor, Sys1p; similar to ADP-ribosylation factor and orthologous to mammalian ARFRP1
codon start: 1
product: Arf family GTPase ARL3
translation: MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKKEYSLAFKALEKIQPTVGQNVATIPVDSKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKIAEHISARDSRVLPISALTGEGVKDAIEWMIVRLERNKKSRPPIYK
SIO_010081: YPL051W
subclass of: SO_0000673
so part of: YPL051W
location: 459963..460559
location: region:459963-460559:1
so has part: feature:459963-460559:1:exon

NP_015274.1
type: Protein
SIO_000068: ncbiprotein

S000005972
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:459963-460559:1:exon

YPL050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNN9
locus tag: YPL050C
so part of: sequence
location: complement(<460779..>461966)
location: region:460779-461966:-1
so has part: feature:460779-461966:-1:exon
subclass of: SO_0000010

856057
type: Gene
SIO_000068: ncbigene

position:460779:-1
position: 460779
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:461966:-1
position: 461966
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:460779-461966:-1:exon

YPL050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNN9
locus tag: YPL050C
product: mannosyltransferase complex subunit MNN9
transcript id: NM_001183864.1
SIO_010081: YPL050C
subclass of: SO_0000673
so part of: YPL050C
location: complement(<460779..>461966)
location: region:460779-461966:-1
so has part: feature:460779-461966:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:460779-461966:-1:exon

YPL050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNN9
locus tag: YPL050C
experiment: EXISTENCE:direct assay:GO:0000009 alpha-1,6-mannosyltransferase activity [PMID:19249370]
experiment: EXISTENCE:direct assay:GO:0000136 mannan polymerase complex [PMID:9430634]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005801 cis-Golgi network [PMID:9430634]
experiment: EXISTENCE:direct assay:GO:0006487 protein N-linked glycosylation [PMID:19249370|PMID:9430634]
note: Subunit of Golgi mannosyltransferase complex; this complex mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation; this complex also contains Anp1p, Mnn10p, Mnn11p, and Hoc1p
codon start: 1
product: mannosyltransferase complex subunit MNN9
translation: MSLSLVSYRLRKNPWVNIFLPVLAIFLIYIIFFQRDQSLLGLNGQSISQHKWAHEKENTFYFPFTKKYKMPKYSYKKKSGWLFNDHVEDIIPEGHIAHYDLNKLHSTSEAAVNKEHILILTPMQTFHQQYWDNLLQLNYPRELIELGFITPRTATGDLALKKLENAIKKVQTDKKTQRFSKITILRQNSQSFDKLMEKERHALDVQKERRAAMALARNELLFSTIGPHTSWVLWLDADIIETPPSLIQDMTKHNKAILAANIYQRFYDEEKKQPSIRPYDFNNWQESDTGLEIASQMGDDEIIVEGYAEIATYRPLMAHFYDANGVPGEEMALDGVGGGCTLVKAEVHRDGAMFPNFPFYHLIETEGFAKMAKRLNYDVFGLPNYLVYHIEEENH
SIO_010081: YPL050C
subclass of: SO_0000673
so part of: YPL050C
location: complement(460779..461966)
location: region:460779-461966:-1
so has part: feature:460779-461966:-1:exon

NP_015275.1
type: Protein
SIO_000068: ncbiprotein

S000005971
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:460779-461966:-1:exon

YPL049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RST1
gene: DIG1
locus tag: YPL049C
gene synonym: RST1
so part of: sequence
location: complement(<462481..>463839)
location: region:462481-463839:-1
so has part: feature:462481-463839:-1:exon
subclass of: SO_0000010

856058
type: Gene
SIO_000068: ncbigene

position:462481:-1
position: 462481
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:463839:-1
position: 463839
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:462481-463839:-1:exon

YPL049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RST1
gene: DIG1
locus tag: YPL049C
gene synonym: RST1
product: Dig1p
transcript id: NM_001183863.1
SIO_010081: YPL049C
subclass of: SO_0000673
so part of: YPL049C
location: complement(<462481..>463839)
location: region:462481-463839:-1
so has part: feature:462481-463839:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:462481-463839:-1:exon

YPL049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RST1
gene: DIG1
locus tag: YPL049C
gene synonym: RST1
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:10825185]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8918885|PMID:9094309]
experiment: EXISTENCE:direct assay:GO:1990526 Ste12p-Dig1p-Dig2p complex [PMID:16782869]
experiment: EXISTENCE:direct assay:GO:1990527 Tec1p-Ste12p-Dig1p complex [PMID:16782869]
experiment: EXISTENCE:genetic interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:9860980|PMID:9094309]
experiment: EXISTENCE:genetic interaction:GO:2000218 negative regulation of invasive growth in response to glucose limitation [PMID:8918885|PMID:9094309]
experiment: EXISTENCE:genetic interaction:GO:2000221 negative regulation of pseudohyphal growth [PMID:8918885|PMID:9094309]
note: MAP kinase-responsive inhibitor of the Ste12p transcription factor; involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p; DIG1 has a paralog, DIG2, that arose from the whole genome duplication
codon start: 1
product: Dig1p
translation: MAVSARLRTTAEDTSIAKSTQDPIGDTEISVANAKGSSDSNIKNSPGGNSVGQESELEHVPEEDDSGDKEADHEDSETATAKKRKAQPLKNPKKSLKRGRVPAPLNLSDSNTNTHGGNIKDGNLASSNSAHFPPVANQNVKSAPAQVTQHSKFQPRVQYLGKASSRQSIQVNNSSNSYGKPHMPSAGIMSAMNPYMPMNRYIMSPYYNPYGIPPPHMLNKPIMTPYVSYPYPMGPRTSIPYAMQGGNARPYEENEYSASNYRNKRVNDSYDSPLSGTASTGKTRRSEEGSRNSSVGSSANAGPTQQRADLRPADMIPAEEYHFERDALLSANTKARSASTSTSTSTSTNRDRSSWHEAEPNKDEEEGTDLAIEDGAVPTPTFTTFQRTSQPQQQSPSLLQGEIRLSSHIFAFEFPLSSSNVDKKMFMSICNKVWNESKELTKKSSSHHRTGK
SIO_010081: YPL049C
subclass of: SO_0000673
so part of: YPL049C
location: complement(462481..463839)
location: region:462481-463839:-1
so has part: feature:462481-463839:-1:exon

NP_015276.1
type: Protein
SIO_000068: ncbiprotein

S000005970
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:462481-463839:-1:exon

YPL048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TEF3
gene: CAM1
locus tag: YPL048W
gene synonym: TEF3
so part of: sequence
location: <464401..>465648
location: region:464401-465648:1
so has part: feature:464401-465648:1:exon
subclass of: SO_0000010

856059
type: Gene
SIO_000068: ncbigene

position:464401:1
position: 464401
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:465648:1
position: 465648
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:464401-465648:1:exon

YPL048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TEF3
gene: CAM1
locus tag: YPL048W
gene synonym: TEF3
product: translation elongation factor EF1B gamma
transcript id: NM_001183862.1
SIO_010081: YPL048W
subclass of: SO_0000673
so part of: YPL048W
location: <464401..>465648
location: region:464401-465648:1
so has part: feature:464401-465648:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:464401-465648:1:exon

YPL048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TEF3
gene: CAM1
locus tag: YPL048W
gene synonym: TEF3
experiment: EXISTENCE:direct assay:GO:0001046 core promoter sequence-specific DNA binding [PMID:12824466]
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:3528160]
experiment: EXISTENCE:direct assay:GO:0005509 calcium ion binding [PMID:8465602]
experiment: EXISTENCE:direct assay:GO:0005543 phospholipid binding [PMID:8465602]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12824466]
experiment: EXISTENCE:direct assay:GO:0006414 translational elongation [PMID:3528160]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:genetic interaction:GO:0006449 regulation of translational termination [PMID:19545407]
experiment: EXISTENCE:mutant phenotype:GO:0003700 DNA-binding transcription factor activity [PMID:12824466]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12824466]
note: One of two isoforms of the gamma subunit of eEF1B; stimulates the release of GDP from eEF1A (Tef1p/Tef2p) post association with the ribosomal complex with eEF1Balpha subunit; nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids
codon start: 1
product: translation elongation factor EF1B gamma
translation: MSQGTLYANFRIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVPAFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK
SIO_010081: YPL048W
subclass of: SO_0000673
so part of: YPL048W
location: 464401..465648
location: region:464401-465648:1
so has part: feature:464401-465648:1:exon

NP_015277.1
type: Protein
SIO_000068: ncbiprotein

S000005969
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:464401-465648:1:exon

YPL047W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SGF11
locus tag: YPL047W
so part of: sequence
location: <465962..>466261
location: region:465962-466261:1
so has part: feature:465962-466261:1:exon
subclass of: SO_0000010

856060
type: Gene
SIO_000068: ncbigene

position:465962:1
position: 465962
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:466261:1
position: 466261
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:465962-466261:1:exon

YPL047W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SGF11
locus tag: YPL047W
product: SAGA histone acetyltransferase complex subunit SGF11
transcript id: NM_001183861.1
SIO_010081: YPL047W
subclass of: SO_0000673
so part of: YPL047W
location: <465962..>466261
location: region:465962-466261:1
so has part: feature:465962-466261:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:465962-466261:1:exon

YPL047W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SGF11
locus tag: YPL047W
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:15282323]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:18488019]
experiment: EXISTENCE:direct assay:GO:0071819 DUBm complex [PMID:20395473]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:15282323]
note: Integral subunit of SAGA histone acetyltransferase complex; regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation
codon start: 1
product: SAGA histone acetyltransferase complex subunit SGF11
translation: MTEETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDPNGSLDINGLQKQQESSQYIHCENCGRDVSANRLAAHLQRCLSRGARR
SIO_010081: YPL047W
subclass of: SO_0000673
so part of: YPL047W
location: 465962..466261
location: region:465962-466261:1
so has part: feature:465962-466261:1:exon

NP_015278.1
type: Protein
SIO_000068: ncbiprotein

S000005968
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:465962-466261:1:exon

YPL046C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ELC1
locus tag: YPL046C
so part of: sequence
location: complement(<466644..>466943)
location: region:466644-466943:-1
so has part: feature:466644-466943:-1:exon
subclass of: SO_0000010

856061
type: Gene
SIO_000068: ncbigene

position:466644:-1
position: 466644
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:466943:-1
position: 466943
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:466644-466943:-1:exon

YPL046C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ELC1
locus tag: YPL046C
product: elongin C
transcript id: NM_001183860.1
SIO_010081: YPL046C
subclass of: SO_0000673
so part of: YPL046C
location: complement(<466644..>466943)
location: region:466644-466943:-1
so has part: feature:466644-466943:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:466644-466943:-1:exon

YPL046C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ELC1
locus tag: YPL046C
experiment: EXISTENCE:direct assay:GO:0000113 nucleotide-excision repair factor 4 complex [PMID:15226437]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:16675952]
experiment: EXISTENCE:direct assay:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:16675952]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:16705154]
experiment: EXISTENCE:mutant phenotype:GO:0031463 Cul3-RING ubiquitin ligase complex [PMID:17296727]
experiment: EXISTENCE:mutant phenotype:GO:0070911 global genome nucleotide-excision repair [PMID:18817898]
experiment: EXISTENCE:physical interaction:GO:0031463 Cul3-RING ubiquitin ligase complex [PMID:16675952]
experiment: EXISTENCE:physical interaction:GO:0070449 elongin complex [PMID:10430890|PMID:10753924]
note: Elongin C, conserved among eukaryotes; forms a complex with Cul3p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; plays a role in global genomic repair
codon start: 1
product: elongin C
translation: MSQDFVTLVSKDDKEYEISRSAAMISPTLKAMIEGPFRESKGRIELKQFDSHILEKAVEYLNYNLKYSGVSEDDDEIPEFEIPTEMSLELLLAADYLSI
SIO_010081: YPL046C
subclass of: SO_0000673
so part of: YPL046C
location: complement(466644..466943)
location: region:466644-466943:-1
so has part: feature:466644-466943:-1:exon

NP_015279.1
type: Protein
SIO_000068: ncbiprotein

S000005967
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:466644-466943:-1:exon

YPL045W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CVT15
alternative label: SVL6
alternative label: VAM9
alternative label: VPT16
gene: VPS16
locus tag: YPL045W
gene synonym: CVT15; SVL6; VAM9; VPT16
so part of: sequence
location: <467260..>469656
location: region:467260-469656:1
so has part: feature:467260-469656:1:exon
subclass of: SO_0000010

856062
type: Gene
SIO_000068: ncbigene

position:467260:1
position: 467260
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:469656:1
position: 469656
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:467260-469656:1:exon

YPL045W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CVT15
alternative label: SVL6
alternative label: VAM9
alternative label: VPT16
gene: VPS16
locus tag: YPL045W
gene synonym: CVT15; SVL6; VAM9; VPT16
product: tethering complex subunit VPS16
transcript id: NM_001183859.1
SIO_010081: YPL045W
subclass of: SO_0000673
so part of: YPL045W
location: <467260..>469656
location: region:467260-469656:1
so has part: feature:467260-469656:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:467260-469656:1:exon

YPL045W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CVT15
alternative label: SVL6
alternative label: VAM9
alternative label: VPT16
gene: VPS16
locus tag: YPL045W
gene synonym: CVT15; SVL6; VAM9; VPT16
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10944212|PMID:9362071]
experiment: EXISTENCE:direct assay:GO:0033263 CORVET complex [PMID:17488625]
experiment: EXISTENCE:direct assay:GO:0035091 phosphatidylinositol binding [PMID:16601699]
experiment: EXISTENCE:direct assay:GO:0035542 regulation of SNARE complex assembly [PMID:18385512]
experiment: EXISTENCE:direct assay:GO:0042144 vacuole fusion, non-autophagic [PMID:10944212]
experiment: EXISTENCE:direct assay:GO:0099022 vesicle tethering [PMID:27307091]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:9362071]
experiment: EXISTENCE:mutant phenotype:GO:0006895 Golgi to endosome transport [PMID:11422941]
experiment: EXISTENCE:mutant phenotype:GO:0007033 vacuole organization [PMID:9362071]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:10944212]
experiment: EXISTENCE:mutant phenotype:GO:0045324 late endosome to vacuole transport [PMID:11422941]
experiment: EXISTENCE:physical interaction:GO:0030897 HOPS complex [PMID:10944212]
note: Subunit of the HOPS and the CORVET complexes; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages
codon start: 1
product: tethering complex subunit VPS16
translation: MKNPSFDWERLKDVFYRSRAIGELKWPTQYEEFKCALSLTVIAVEIQDFIQVYNYFGQLLGKINLQRIHEDIIKFEFDKDEKLILVTKSSIKIVKGWSPLTIESVPLQDPTIDTIWDYHNGIMLLAKSRDIYKLNGNEWELLYENKDKKYNLLTKNHWSCNDDSIILLDVDHVYQVSTSNGALLKLITDSSWHKVTISSRGFICLYNMKDNKLQIFRDPARILMEHNLDSTPDDICWCGNDTVACSFEDEIKLYGPDGLYVTFWYPFTVTNLRAEVDGLKVITTEKIYFLSRVQPQTSNIFRIGSTEPGAMLVDSFSLLEDHAPKAIEILKNFVLEKGVLDCIAAAIDEFEPKLQKMLLNAASYGKASLQYKSFDASIFVNACNTIKLLNCFRSFGIFLTVEEYRCISLKGVIDRLLKYHRYYECIQICKLANERFLLGYVFTEWAKDKIKGSPDMEDDELLDKIKSRLSVIDMTDTLQMVAVAKVAYLEGRFQLSRNLALLEKNEEARIEQLYNLDDDSIALKECIKVQNYSLTISLLIALSKKLTNSQLTKLLIIDMFNNPLYLYYMRMDKAYLYDFYRQTDRFIDLAHVLLQQGKEQQSLHSFLPQIKDLYSQVQNSEVVNNTIEQLQRQEKLWIYQESLGKRFAISFTNMTLDQTLSKLIETGQDKQVKEIVKKFKISEKKLYHLKCKTLVEAKKFDELLQFAQSRKSPIGYMPFYTYLKSRGHMDKASPYVNMIPGLSYQEKKKLYVECRGFRDAIQLAGKEKDIPGLKEIYNIIPPNEPELKALANETMSRI
SIO_010081: YPL045W
subclass of: SO_0000673
so part of: YPL045W
location: 467260..469656
location: region:467260-469656:1
so has part: feature:467260-469656:1:exon

NP_015280.1
type: Protein
SIO_000068: ncbiprotein

S000005966
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:467260-469656:1:exon

YPL043W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NOP77
gene: NOP4
locus tag: YPL043W
gene synonym: NOP77
so part of: sequence
location: <469939..>471996
location: region:469939-471996:1
so has part: feature:469939-471996:1:exon
subclass of: SO_0000010

856063
type: Gene
SIO_000068: ncbigene

position:469939:1
position: 469939
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:471996:1
position: 471996
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:469939-471996:1:exon

YPL043W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NOP77
gene: NOP4
locus tag: YPL043W
gene synonym: NOP77
product: mRNA-binding ribosome biosynthesis protein NOP4
transcript id: NM_001183857.1
SIO_010081: YPL043W
subclass of: SO_0000673
so part of: YPL043W
location: <469939..>471996
location: region:469939-471996:1
so has part: feature:469939-471996:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:469939-471996:1:exon

YPL043W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NOP77
gene: NOP4
locus tag: YPL043W
gene synonym: NOP77
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0070180 large ribosomal subunit rRNA binding [PMID:21811236]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:8039505]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:8039505]
note: Nucleolar protein; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs); human ortholog RBM28 implicated in ANE syndrome
codon start: 1
product: mRNA-binding ribosome biosynthesis protein NOP4
translation: MEETIENVEVPSSNVSKQNDDGLDMKTLFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDTNKRSRGFGFVSFAVEDDTKEALAKARKTKFNGHILRVDIAKRRDRSKKTSEVVEKSTPESSEKITGQNNEDEDDADGEDSMLKGKPKLIIRNMPWSCRDPVKLKKIFGRYGTVVEATIPRKRDGKLCGFAFVTMKKISNCRIALENTKDLKIDGRKVAVDFAVQKNRWEDYKKAQPEMNDKDDNESGNEDAEENHDDEEDENEEEDRQVDQASKNKESKRKAQNKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKSTGLAKGTAFVAFKDQYTYNECIKNAPAAGSTSLLIGDDVMPEYVYEGRVLSITPTLVREDAGRMAEKNAAKRKEALGKAPGEKDRRNLYLLNEGRVVEGSKMADLLTNTDMEIREKSYKLRVEQLKKNPSLHLSMTRLAIRNLPRAMNDKALKALARKAVVEFATEVKNKERHPLSKEEIIRSTKEKYKFMGPDEIEAQKKKDKKSGVVKQAKVIMEVKGSTAGRSRGYGFVEFRDHKNALMGLRWLNCHAVTSDEILEGLNDDEKKQVDNDLGKGRRLCVEFAIENSNVVKRRREQLKQARTKRTRPDNEDTGDVGESENKKPKKEEATTPTNPDDKKMGDDIKRIIGFKRKRKHAKK
SIO_010081: YPL043W
subclass of: SO_0000673
so part of: YPL043W
location: 469939..471996
location: region:469939-471996:1
so has part: feature:469939-471996:1:exon

NP_015282.1
type: Protein
SIO_000068: ncbiprotein

S000005964
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:469939-471996:1:exon

YPL042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDK8
alternative label: GIG2
alternative label: NUT7
alternative label: RYE5
alternative label: SRB10
alternative label: SSX7
alternative label: UME5
alternative label: URR1
gene: SSN3
locus tag: YPL042C
gene synonym: CDK8; GIG2; NUT7; RYE5; SRB10; SSX7; UME5; URR1
so part of: sequence
location: complement(<473040..>474707)
location: region:473040-474707:-1
so has part: feature:473040-474707:-1:exon
subclass of: SO_0000010

856065
type: Gene
SIO_000068: ncbigene

position:473040:-1
position: 473040
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:474707:-1
position: 474707
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:473040-474707:-1:exon

YPL042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDK8
alternative label: GIG2
alternative label: NUT7
alternative label: RYE5
alternative label: SRB10
alternative label: SSX7
alternative label: UME5
alternative label: URR1
gene: SSN3
locus tag: YPL042C
gene synonym: CDK8; GIG2; NUT7; RYE5; SRB10; SSX7; UME5; URR1
product: cyclin-dependent serine/threonine protein kinase SSN3
transcript id: NM_001183856.1
SIO_010081: YPL042C
subclass of: SO_0000673
so part of: YPL042C
location: complement(<473040..>474707)
location: region:473040-474707:-1
so has part: feature:473040-474707:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:473040-474707:-1:exon

YPL042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDK8
alternative label: GIG2
alternative label: NUT7
alternative label: RYE5
alternative label: SRB10
alternative label: SSX7
alternative label: UME5
alternative label: URR1
gene: SSN3
locus tag: YPL042C
gene synonym: CDK8; GIG2; NUT7; RYE5; SRB10; SSX7; UME5; URR1
EC number: 2.7.11.22
EC number: 2.7.11.23
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004693 cyclin-dependent protein serine/threonine kinase activity [PMID:11331604]
experiment: EXISTENCE:direct assay:GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity [PMID:9702190]
experiment: EXISTENCE:direct assay:GO:0016592 mediator complex [PMID:11383511|PMID:12200444]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:9702190]
experiment: EXISTENCE:genetic interaction:GO:0060258 negative regulation of filamentous growth [PMID:12520306]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:16109375]
experiment: EXISTENCE:mutant phenotype:GO:0000435 positive regulation of transcription from RNA polymerase II promoter by galactose [PMID:15601835]
experiment: EXISTENCE:mutant phenotype:GO:0006979 response to oxidative stress [PMID:31506296]
experiment: EXISTENCE:mutant phenotype:GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity [PMID:9702190]
experiment: EXISTENCE:mutant phenotype:GO:0031648 protein destabilization [PMID:12520306]
experiment: EXISTENCE:mutant phenotype:GO:0060258 negative regulation of filamentous growth [PMID:12520306]
experiment: EXISTENCE:mutant phenotype:GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay [PMID:17660569]
experiment: EXISTENCE:mutant phenotype:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:9702190]
experiment: EXISTENCE:physical interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:11226276]
note: Component of the RNA polymerase II mediator complex; cyclin-dependent protein kinase involved in phosphorylation of the mediator component Pgd1p and suppression of transcription activation by RNA polymerase II; involved in glucose repression
codon start: 1
product: cyclin-dependent serine/threonine protein kinase SSN3
translation: MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTKNNTQASGITAGAAANALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR
SIO_010081: YPL042C
subclass of: SO_0000673
so part of: YPL042C
location: complement(473040..474707)
location: region:473040-474707:-1
so has part: feature:473040-474707:-1:exon

NP_015283.1
type: Protein
SIO_000068: ncbiprotein

S000005963
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:473040-474707:-1:exon

YPL041C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX11
locus tag: YPL041C
so part of: sequence
location: complement(<475118..>475741)
location: region:475118-475741:-1
so has part: feature:475118-475741:-1:exon
subclass of: SO_0000010

856066
type: Gene
SIO_000068: ncbigene

position:475118:-1
position: 475118
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:475741:-1
position: 475741
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:475118-475741:-1:exon

YPL041C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX11
locus tag: YPL041C
product: Mrx11p
transcript id: NM_001183855.1
SIO_010081: YPL041C
subclass of: SO_0000673
so part of: YPL041C
location: complement(<475118..>475741)
location: region:475118-475741:-1
so has part: feature:475118-475741:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:475118-475741:-1:exon

YPL041C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX11
locus tag: YPL041C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:26928762]
note: Protein that associates with mitochondrial ribosome; SWAT-GFP and mCherry fusion proteins localize to the mitochondria; involved in maintenance of telomere length
codon start: 1
product: Mrx11p
translation: MTVMNLFFRPCQLQMGSGPLELMLKRPTQLTTFMNTRPGGSTQIRFISGNLDPVKRREDRLRKIFSKSRLLTRLNKNPKFSHYFDRLSEAGTVPTLTSFFILHEVTAILPLFLLWWLLYNLDLSDDFKLPNFLNGLMDSCHTAMEKFVGKRYQECLNKNKLILSGTVAYVTVKLLYPVRIFISIWGAPYFGKWLLLPFQKLKHLIKK
SIO_010081: YPL041C
subclass of: SO_0000673
so part of: YPL041C
location: complement(475118..475741)
location: region:475118-475741:-1
so has part: feature:475118-475741:-1:exon

NP_015284.1
type: Protein
SIO_000068: ncbiprotein

S000005962
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:475118-475741:-1:exon

YPL040C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ISM1
locus tag: YPL040C
so part of: sequence
location: complement(<475993..>479001)
location: region:475993-479001:-1
so has part: feature:475993-479001:-1:exon
subclass of: SO_0000010

856067
type: Gene
SIO_000068: ncbigene

position:475993:-1
position: 475993
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:479001:-1
position: 479001
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:475993-479001:-1:exon

YPL040C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ISM1
locus tag: YPL040C
product: isoleucine--tRNA ligase ISM1
transcript id: NM_001183854.1
SIO_010081: YPL040C
subclass of: SO_0000673
so part of: YPL040C
location: complement(<475993..>479001)
location: region:475993-479001:-1
so has part: feature:475993-479001:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:475993-479001:-1:exon

YPL040C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ISM1
locus tag: YPL040C
EC number: 6.1.1.5
experiment: EXISTENCE:curator inference:GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation [PMID:7607232]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:7607232]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:7607232]
note: Mitochondrial isoleucyl-tRNA synthetase; null mutant is deficient in respiratory growth; human homolog IARS2 implicated in mitochondrial diseases, can partially complement yeast null mutant
codon start: 1
product: isoleucine--tRNA ligase ISM1
translation: MKRSRLVPQHIFSIISKRYLAKHAYQKTLNLPKTKFPNRSNLEITLRELIPKSSQLVYKEQLRDFFEEFSKLNTTDEKLEFIKEKLFILHDGPPYANGELHLGHALNKILKDIINRYQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQIESISPLKIRSMALKHAQKAIKRQRETFQHFAILTDWETPYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTALAEGELEYNENHKSIAAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNRAICFNQDFSYSLLRLNSELILVETGSIDKLGLTTNSFETIKQFQGTHLNGLYYQNLLVDDKVGRPLLHGAHVTSGTGTGLVHTAPGHGQDDYLIGIQNGLEIYSPVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIILCKLSDLNLLYKSHEYTHSYPYDWRSKKPVIIRATPQWFADLHDVKNLALESISRVKFCPKRGYSRLSSFMKSRNEWCISRQRSWGIPILSFYKKSEPDSVLMNSEILAHAIEKIKQKGINAWFNDKDNDMKEWLPEKYHDVAHEYCRSQDTMDVWFDSGSSWSVIKDFYEKSLKLSKLPSPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKSVGNTISPEAIIRGDENLGLPALGVDGLRYLIAQSNFTTDIVAGPTVMKHVGEALKKVRLTFRYLLSNLQKSQDFNLLPIEQLRRVDQYTLYKINELLETTREHYQKYNFSKVLITLQYHLNNELSAFYFDISKDILYSNQISSLARRQVQTTLVHILNAYRAILAPILPVMVQEVWKYIPEGWLQGQEHIDINPMRGKWPFLDSNTEIVTSFENFELKILKQFQEEFKRLSLEEGVTKTTHSHVTIFTKHHLPFSSDELCDILQSSAVDILQMDDNNNSLPTIELGSGINVQILVERSKRHNCPRCWKANSAEEDKLCDRCKEAVDHLMS
SIO_010081: YPL040C
subclass of: SO_0000673
so part of: YPL040C
location: complement(475993..479001)
location: region:475993-479001:-1
so has part: feature:475993-479001:-1:exon

NP_015285.1
type: Protein
SIO_000068: ncbiprotein

S000005961
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:475993-479001:-1:exon

YPL039W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL039W
so part of: sequence
location: <479225..>480175
location: region:479225-480175:1
so has part: feature:479225-480175:1:exon
subclass of: SO_0000010

856068
type: Gene
SIO_000068: ncbigene

position:479225:1
position: 479225
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:480175:1
position: 480175
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:479225-480175:1:exon

YPL039W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL039W
product: uncharacterized protein
transcript id: NM_001183853.1
SIO_010081: YPL039W
subclass of: SO_0000673
so part of: YPL039W
location: <479225..>480175
location: region:479225-480175:1
so has part: feature:479225-480175:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:479225-480175:1:exon

YPL039W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL039W
note: hypothetical protein; YPL039W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLKEEYNLSGADNMASAELSFKKQKVVLKKFMIAQVTKGIMQRYASLLVTMPSDDDNAIIGTNHLKTTKFLEIILHRAKSSHLQFKKVCCIVIKFLDCCSKETNYMKFLKFSLHKLFVAAFILSVPNVVGDDRDRITTRDETYHLYSQITGLPLEEVINCCSIVRPVLIRRSRQQRRQMLSRREQHSYFLRSSFMNSNSSASPFFSTNRSADDLHVHTRAYSLHSHSDGEGQDRRSEHEETHSMGADADTYRQTTFIPDTPNGLHSRSLIECGIEPTQVSDSGEWSGQSNGYVLVTELQEFNKMGKKLVQEAFRIV
SIO_010081: YPL039W
subclass of: SO_0000673
so part of: YPL039W
location: 479225..480175
location: region:479225-480175:1
so has part: feature:479225-480175:1:exon

NP_015286.1
type: Protein
SIO_000068: ncbiprotein

S000005960
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:479225-480175:1:exon

YPL038W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL038W-A
so part of: sequence
location: <480182..>480373
location: region:480182-480373:1
so has part: feature:480182-480373:1:exon
subclass of: SO_0000010

1466521
type: Gene
SIO_000068: ncbigene

position:480182:1
position: 480182
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:480373:1
position: 480373
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:480182-480373:1:exon

YPL038W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL038W-A
product: uncharacterized protein
transcript id: NM_001184580.1
SIO_010081: YPL038W-A
subclass of: SO_0000673
so part of: YPL038W-A
location: <480182..>480373
location: region:480182-480373:1
so has part: feature:480182-480373:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:480182-480373:1:exon

YPL038W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL038W-A
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MVCRFVHHSRVIFISIYDFLSTKGKKNMYNYTQEKKTKQKNTFTQASIYYENFFESYRTISCL
SIO_010081: YPL038W-A
subclass of: SO_0000673
so part of: YPL038W-A
location: 480182..480373
location: region:480182-480373:1
so has part: feature:480182-480373:1:exon

NP_878182.1
type: Protein
SIO_000068: ncbiprotein

S000028588
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:480182-480373:1:exon

YPL038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET31
locus tag: YPL038W
so part of: sequence
location: <480535..>481068
location: region:480535-481068:1
so has part: feature:480535-481068:1:exon
subclass of: SO_0000010

856069
type: Gene
SIO_000068: ncbigene

position:480535:1
position: 480535
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:481068:1
position: 481068
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:480535-481068:1:exon

YPL038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET31
locus tag: YPL038W
product: Met31p
transcript id: NM_001183852.1
SIO_010081: YPL038W
subclass of: SO_0000673
so part of: YPL038W
location: <480535..>481068
location: region:480535-481068:1
so has part: feature:480535-481068:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:480535-481068:1:exon

YPL038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET31
locus tag: YPL038W
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9799240]
experiment: EXISTENCE:direct assay:GO:0000987 cis-regulatory region sequence-specific DNA binding [PMID:9199298]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9199298]
experiment: EXISTENCE:direct assay:GO:0031335 regulation of sulfur amino acid metabolic process [PMID:9199298]
experiment: EXISTENCE:genetic interaction:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9799240]
experiment: EXISTENCE:genetic interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9199298]
experiment: EXISTENCE:genetic interaction:GO:0031335 regulation of sulfur amino acid metabolic process [PMID:9199298]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:22696683]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9199298]
experiment: EXISTENCE:mutant phenotype:GO:0031335 regulation of sulfur amino acid metabolic process [PMID:9199298]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:22696683]
experiment: EXISTENCE:physical interaction:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9799240]
note: Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication
codon start: 1
product: Met31p
translation: MKLAQDMNVDEIFLKQAAEAIAVISSSPTHTDPIIRELLHRIRQSSPLSAVIPAPENVLKAGEPENMARGLIRIPETQTKRTGGNNHSKEGAQLYSCAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRHSNTLTCQRNRKKLSEGSDVDVDELIKDAIKNGTGLL
SIO_010081: YPL038W
subclass of: SO_0000673
so part of: YPL038W
location: 480535..481068
location: region:480535-481068:1
so has part: feature:480535-481068:1:exon

NP_015287.1
type: Protein
SIO_000068: ncbiprotein

S000005959
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:480535-481068:1:exon

YPL037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EGD1
locus tag: YPL037C
so part of: sequence
location: complement(<481428..>481901)
location: region:481428-481901:-1
so has part: feature:481428-481901:-1:exon
subclass of: SO_0000010

856070
type: Gene
SIO_000068: ncbigene

position:481428:-1
position: 481428
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:481901:-1
position: 481901
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:481428-481901:-1:exon

YPL037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EGD1
locus tag: YPL037C
product: Egd1p
transcript id: NM_001183851.1
SIO_010081: YPL037C
subclass of: SO_0000673
so part of: YPL037C
location: complement(<481428..>481901)
location: region:481428-481901:-1
so has part: feature:481428-481901:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:481428-481901:-1:exon

YPL037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EGD1
locus tag: YPL037C
experiment: EXISTENCE:direct assay:GO:0005854 nascent polypeptide-associated complex [PMID:10219998]
experiment: EXISTENCE:genetic interaction:GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane [PMID:10518932]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:9482879]
note: Subunit beta1 of the nascent polypeptide-associated complex (NAC); involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b; EGD1 has a paralog, BTT1, that arose from the whole genome duplication
codon start: 1
product: Egd1p
translation: MPIDQEKLAKLQKLSANNKVGGTRRKLNKKAGSSAGANKDDTKLQSQLAKLHAVTIDNVAEANFFKDDGKVMHFNKVGVQVAAQHNTSVFYGLPQEKNLQDLFPGIISQLGPEAIQALSQLAAQMEKHEAKAPADAEKKDEAIPELVEGQTFDADVE
SIO_010081: YPL037C
subclass of: SO_0000673
so part of: YPL037C
location: complement(481428..481901)
location: region:481428-481901:-1
so has part: feature:481428-481901:-1:exon

NP_015288.1
type: Protein
SIO_000068: ncbiprotein

S000005958
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:481428-481901:-1:exon

YPL036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PMA2
locus tag: YPL036W
so part of: sequence
location: <482843..>485686
location: region:482843-485686:1
so has part: feature:482843-485686:1:exon
subclass of: SO_0000010

856071
type: Gene
SIO_000068: ncbigene

position:482843:1
position: 482843
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:485686:1
position: 485686
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:482843-485686:1:exon

YPL036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PMA2
locus tag: YPL036W
product: H(+)-exporting P2-type ATPase PMA2
transcript id: NM_001183850.1
SIO_010081: YPL036W
subclass of: SO_0000673
so part of: YPL036W
location: <482843..>485686
location: region:482843-485686:1
so has part: feature:482843-485686:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:482843-485686:1:exon

YPL036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PMA2
locus tag: YPL036W
EC number: 7.1.2.1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:8396147|PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0008553 P-type proton-exporting transporter activity [PMID:8396147]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:1902600 proton transmembrane transport [PMID:8396147]
note: Plasma membrane H+-ATPase; isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential
codon start: 1
product: H(+)-exporting P2-type ATPase PMA2
translation: MSSTEAKQYKEKPSKEYLHASDGDDPANNSAASSSSSSSTSTSASSSAAAVPRKAAAASAADDSDSDEDIDQLIDELQSNYGEGDESGEEEVRTDGVHAGQRVVPEKDLSTDPAYGLTSDEVARRRKKYGLNQMAEENESLIVKFLMFFVGPIQFVMEAAAILAAGLSDWVDVGVICALLLLNASVGFIQEFQAGSIVDELKKTLANTATVIRDGQLIEIPANEVVPGEILQLESGTIAPADGRIVTEDCFLQIDQSAITGESLAAEKHYGDEVFSSSTVKTGEAFMVVTATGDNTFVGRAAALVGQASGVEGHFTEVLNGIGIILLVLVIATLLLVWTACFYRTVGIVSILRYTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHEPYTVEGVSPDDLMLTACLAASRKKKGLDAIDKAFLKSLIEYPKAKDALTKYKVLEFHPFDPVSKKVTAVVESPEGERIVCVKGAPLFVLKTVEEDHPIPEDVHENYENKVAELASRGFRALGVARKRGEGHWEILGVMPCMDPPRDDTAQTINEARNLGLRIKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYRVVEILQNRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSLHLEIFLGLWIAILNNSLDINLIVFIAIFADVATLTIAYDNAPYAPEPVKWNLPRLWGMSIILGIVLAIGSWITLTTMFLPNGGIIQNFGAMNGVMFLQISLTENWLIFVTRAAGPFWSSIPSWQLAGAVFAVDIIATMFTLFGWWSENWTDIVSVVRVWIWSIGIFCVLGGFYYIMSTSQAFDRLMNGKSLKEKKSTRSVEDFMAAMQRVSTQHEKSS
SIO_010081: YPL036W
subclass of: SO_0000673
so part of: YPL036W
location: 482843..485686
location: region:482843-485686:1
so has part: feature:482843-485686:1:exon

NP_015289.1
type: Protein
SIO_000068: ncbiprotein

S000005957
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:482843-485686:1:exon

YPL034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPL034W
so part of: sequence
location: <486712..>487209
location: region:486712-487209:1
so has part: feature:486712-487209:1:exon
subclass of: SO_0000010

856072
type: Gene
SIO_000068: ncbigene

position:486712:1
position: 486712
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:487209:1
position: 487209
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:486712-487209:1:exon

YPL034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPL034W
product: uncharacterized protein
transcript id: NM_001183848.1
SIO_010081: YPL034W
subclass of: SO_0000673
so part of: YPL034W
location: <486712..>487209
location: region:486712-487209:1
so has part: feature:486712-487209:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:486712-487209:1:exon

YPL034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPL034W
note: hypothetical protein; YPL034W is not essential gene
codon start: 1
product: uncharacterized protein
translation: MTTRKTVDSRLLEWQTTCKHPVINLTPEKVDKLYHLKLKSESKNISSNRLLPISLSSLQKKMEKLFIKDKSHSHKPSLPDPKVPTLRTYKDGGFFISGKGSMKLPDIESAIHKFLWKKYGKGLVYCYGCDPTGKKRHTEWFNVPVLELPSVLRLIDSYCLGGESR
SIO_010081: YPL034W
subclass of: SO_0000673
so part of: YPL034W
location: 486712..487209
location: region:486712-487209:1
so has part: feature:486712-487209:1:exon

NP_015291.1
type: Protein
SIO_000068: ncbiprotein

S000005955
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:486712-487209:1:exon

YPL033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SRL4
locus tag: YPL033C
so part of: sequence
location: complement(<487362..>488207)
location: region:487362-488207:-1
so has part: feature:487362-488207:-1:exon
subclass of: SO_0000010

856074
type: Gene
SIO_000068: ncbigene

position:487362:-1
position: 487362
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:488207:-1
position: 488207
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:487362-488207:-1:exon

YPL033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SRL4
locus tag: YPL033C
product: Srl4p
transcript id: NM_001183847.1
SIO_010081: YPL033C
subclass of: SO_0000673
so part of: YPL033C
location: complement(<487362..>488207)
location: region:487362-488207:-1
so has part: feature:487362-488207:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:487362-488207:-1:exon

YPL033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SRL4
locus tag: YPL033C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0009200 deoxyribonucleoside triphosphate metabolic process [PMID:18337697]
note: hypothetical protein; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p
codon start: 1
product: Srl4p
translation: MKKTIYKVLVSFYQYVGLGKKFHPSHDTVLIIGGSSNELGIELCETFIEDYHTKVINIDTIDSINGKNARRSEKLYTFISCKDFSDIKCLEESMLYLQNLEIIPTVLINNMQEGIESTLLKEDKFLRLDEESLNEFEKIVRYNLQSVILITKFCLSNIFPKVQAEAQEKAKGFYIVNISSVLTLKPCKSGTHFITSKCGINSFHDGITSELKLKDSNLNVKTLIAYLPSFESEAHWKRLSPSISKHLVHCLLEGRYGDTILESKRSIGDILLITGFKSSFT
SIO_010081: YPL033C
subclass of: SO_0000673
so part of: YPL033C
location: complement(487362..488207)
location: region:487362-488207:-1
so has part: feature:487362-488207:-1:exon

NP_015292.1
type: Protein
SIO_000068: ncbiprotein

S000005954
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:487362-488207:-1:exon

YPL032C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SVL3
locus tag: YPL032C
so part of: sequence
location: complement(<488887..>491364)
location: region:488887-491364:-1
so has part: feature:488887-491364:-1:exon
subclass of: SO_0000010

856075
type: Gene
SIO_000068: ncbigene

position:488887:-1
position: 488887
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:491364:-1
position: 491364
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:488887-491364:-1:exon

YPL032C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SVL3
locus tag: YPL032C
product: Svl3p
transcript id: NM_001183846.1
SIO_010081: YPL032C
subclass of: SO_0000673
so part of: YPL032C
location: complement(<488887..>491364)
location: region:488887-491364:-1
so has part: feature:488887-491364:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:488887-491364:-1:exon

YPL032C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SVL3
locus tag: YPL032C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:22842922|PMID:32491201]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095|PMID:22842922|PMID:32491201]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:9751732]
note: hypothetical protein; mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; relocalizes from bud neck to cytoplasm upon DNA replication stress; SVL3 has a paralog, PAM1, that arose from the whole genome duplication
codon start: 1
product: Svl3p
translation: MSSSSLRVLAIGNNPNILFYTSRFQLAKNIDLYHVNDSKSCQFEIETEYYGKDRFELENHFTSIEHLTEALSSKSSEAVFDIIIMSAPSLQELSSLASKLTSIIDSNTKIFLESSGFIQLEPFVKLSMESPHVNVFSILTDLDIRQIGPNHFKHFPSTAKENTIYLGESKSSTEKYSSGVITLLTTFEKLFAKLFSNIKINLCNFSSIEFLSQQWKLAISRICFDPLLIMFEQENPSDLDQQIIAKPLISGLVTEIITVAKTMGARLNSSHDNENSLLSLWKNSYHSTNKPPALVYHFIHQTTPLNIDILLLQTILLADDFGIKTPYLEFLYSVLSQFERLNSGKSKWFIRSDEKTQILQSLQKSQKNESALQTQITSLQGQISKLRQELLMQAKQHEMETNELKEKHQVALKAQAQAQAQAQSQAQTSIEALTPTEATNQSDTNEYKATGTPNLRDIEDMALYSVNYGDSPVRSPPPVVSSQPQMNSPLSSHSQTFGENNGTNDKLLQERELQLRKKELELQERELEFQKRALQQQRFNNSNNSIPRKPSFPQLQQSANVRSNSRGMHGTNGAMSQPASAGNFVDPISSSIAAYDPQQPPSLPLQQPQQSVQVQPFHSHSIKPTSRKNRNSNMPNIGNPSSINMSDFGRPPNNSSQTRLNSMPTHSIVNQNRLRSQQSKNKLNMPHATNPNNTFNQVPAPSLNNHVPTQRQFSSSTMIEVTNNNNKVNNSSSNPDISTNSVVHNAMQFTNTNNNTSSTVDINDPKNIAPPPTTSVSAPSTPTLSSSSQMANMASPSTDNGDNEEKNGGKKKRFGLFKKKNKSKK
SIO_010081: YPL032C
subclass of: SO_0000673
so part of: YPL032C
location: complement(488887..491364)
location: region:488887-491364:-1
so has part: feature:488887-491364:-1:exon

NP_015293.1
type: Protein
SIO_000068: ncbiprotein

S000005953
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:488887-491364:-1:exon

YPL031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LDB15
gene: PHO85
locus tag: YPL031C
gene synonym: LDB15
so part of: sequence
location: complement(<492018..>493037)
location: region:492018-493037:-1
so has part: feature:492018-493037:-1:exon
subclass of: SO_0000010

856076
type: Gene
SIO_000068: ncbigene

position:492018:-1
position: 492018
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:493037:-1
position: 493037
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:492018-493037:-1:exon

YPL031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LDB15
gene: PHO85
locus tag: YPL031C
gene synonym: LDB15
product: cyclin-dependent serine/threonine-protein kinase PHO85
transcript id: NM_001183845.1
SIO_010081: YPL031C
subclass of: SO_0000673
so part of: YPL031C
location: complement(join(<492018..492918,493021..>493037))
location: region:492018-493037:-1
so has part: feature:493021-493037:-1:exon
so has part: feature:492018-492918:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:493021-493037:-1:exon

position:493021:-1
position: 493021
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:492018-492918:-1:exon

position:492918:-1
position: 492918
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPL031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LDB15
gene: PHO85
locus tag: YPL031C
gene synonym: LDB15
EC number: 2.7.11.22
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004693 cyclin-dependent protein serine/threonine kinase activity [PMID:12407105|PMID:7973730|PMID:7973731|PMID:8108735|PMID :9584169|PMID:19823668]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9853758]
experiment: EXISTENCE:direct assay:GO:0019216 regulation of lipid metabolic process [PMID:31678512]
experiment: EXISTENCE:direct assay:GO:0032880 regulation of protein localization [PMID:8539622]
experiment: EXISTENCE:direct assay:GO:0046822 regulation of nucleocytoplasmic transport [PMID:31422915]
experiment: EXISTENCE:direct assay:GO:0055088 lipid homeostasis [PMID:31678512]
experiment: EXISTENCE:direct assay:GO:0071073 positive regulation of phospholipid biosynthetic process [PMID:27743455]
experiment: EXISTENCE:direct assay:GO:1901987 regulation of cell cycle phase transition [PMID:29146254]
experiment: EXISTENCE:direct assay:GO:1990860 Pho85-Pho80 CDK-cyclin complex [PMID:8108735]
experiment: EXISTENCE:genetic interaction:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668|PMID:15738404]
experiment: EXISTENCE:genetic interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:3915785]
experiment: EXISTENCE:genetic interaction:GO:0006974 cellular response to DNA damage stimulus [PMID:16964260]
experiment: EXISTENCE:genetic interaction:GO:0031505 fungal-type cell wall organization [PMID:12077337]
experiment: EXISTENCE:genetic interaction:GO:0031647 regulation of protein stability [PMID:16611745]
experiment: EXISTENCE:genetic interaction:GO:0032878 regulation of establishment or maintenance of cell polarity [PMID:17853895]
experiment: EXISTENCE:genetic interaction:GO:0043433 negative regulation of DNA-binding transcription factor activity [PMID:12101234]
experiment: EXISTENCE:genetic interaction:GO:0045936 negative regulation of phosphate metabolic process [PMID:3915785]
experiment: EXISTENCE:genetic interaction:GO:0050849 negative regulation of calcium-mediated signaling [PMID:16455487]
experiment: EXISTENCE:mutant phenotype:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668]
experiment: EXISTENCE:mutant phenotype:GO:0004693 cyclin-dependent protein serine/threonine kinase activity [PMID:9593297]
experiment: EXISTENCE:mutant phenotype:GO:0006974 cellular response to DNA damage stimulus [PMID:16964260]
experiment: EXISTENCE:mutant phenotype:GO:0016239 positive regulation of macroautophagy [PMID:20417603]
experiment: EXISTENCE:mutant phenotype:GO:0016242 negative regulation of macroautophagy [PMID:20417603]
experiment: EXISTENCE:mutant phenotype:GO:0031647 regulation of protein stability [PMID:16508019]
experiment: EXISTENCE:mutant phenotype:GO:0043433 negative regulation of DNA-binding transcription factor activity [PMID:16455487]
experiment: EXISTENCE:mutant phenotype:GO:0045719 negative regulation of glycogen biosynthetic process [PMID:9584169]
experiment: EXISTENCE:physical interaction:GO:0000307 cyclin-dependent protein kinase holoenzyme complex [PMID:7973730|PMID:7973731|PMID:8108735|PMID:9584169|PMID: 16611745]
note: Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation
codon start: 1
product: cyclin-dependent serine/threonine-protein kinase PHO85
translation: MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS
SIO_010081: YPL031C
subclass of: SO_0000673
so part of: YPL031C
location: complement(join(492018..492918,493021..493037))
location: region:492018-493037:-1
so has part: feature:493021-493037:-1:exon
so has part: feature:492018-492918:-1:exon

NP_015294.1
type: Protein
SIO_000068: ncbiprotein

S000005952
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:493021-493037:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:492018-492918:-1:exon

YPL030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRM44
locus tag: YPL030W
so part of: sequence
location: <493543..>495246
location: region:493543-495246:1
so has part: feature:493543-495246:1:exon
subclass of: SO_0000010

856077
type: Gene
SIO_000068: ncbigene

position:493543:1
position: 493543
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:495246:1
position: 495246
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:493543-495246:1:exon

YPL030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TRM44
locus tag: YPL030W
product: tRNA (uracil) methyltransferase
transcript id: NM_001183844.1
SIO_010081: YPL030W
subclass of: SO_0000673
so part of: YPL030W
location: <493543..>495246
location: region:493543-495246:1
so has part: feature:493543-495246:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:493543-495246:1:exon

YPL030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TRM44
locus tag: YPL030W
EC number: 2.1.1.211
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016300 tRNA (uracil) methyltransferase activity [PMID:18025252]
experiment: EXISTENCE:direct assay:GO:0030488 tRNA methylation [PMID:18025252]
experiment: EXISTENCE:mutant phenotype:GO:0002128 tRNA nucleoside ribose methylation [PMID:32053677]
experiment: EXISTENCE:mutant phenotype:GO:0016300 tRNA (uracil) methyltransferase activity [PMID:18025252]
experiment: EXISTENCE:mutant phenotype:GO:0030488 tRNA methylation [PMID:18025252]
note: tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene
codon start: 1
product: tRNA (uracil) methyltransferase
translation: MTGDGSAHISKNNQNQHKDRFKFIVNDKSILGPQWLSLYQTDGKVTFAKSHFEQAMMNVIREPNINSTVILRADILKEINHAAEAGSEPKFDESVLKKFEIDNGNESGEEDVKKINIEDLNIRSCETSESLKLSPVHEFVRRIIPRNFYKDAIINQTCLILNSKDPNFQETSLIVYTPHINSEKDCPFYIPRTQSVGILLHQSVLSVHYIPFPEDKTAFTDESERVVRTAYRLLQTANKHSKGVMQGYEKRVNHDQVVNKVNFQNTYIVLKKKYSKFLVENWAESTDPKKHVFEDIAIAAFLIELWIKVYGPDFRSKMQFRDLGCGNGALCYILLSESIKGLGIDARKRKSWSIYPPEVQSSLKEQVIIPSILLRPHPALKRQVPHLEHNGRFFPVKVTHEVIAPATVVYSSEDLLKSPQVNTAEFPPDTFIIGNHSDELTCWIPLLGHPYMVIPCCSHNFSGQRVRFNVRKRSPRSNEIKNQNNSKSTYSGLVDHVEYISSRVGWKVEKEMLRIPSTRNAAIIGVENATLKHFPTQAVYDMIWEDGGAEGWIQNTMSLLKRNPRNH
SIO_010081: YPL030W
subclass of: SO_0000673
so part of: YPL030W
location: 493543..495246
location: region:493543-495246:1
so has part: feature:493543-495246:1:exon

NP_015295.1
type: Protein
SIO_000068: ncbiprotein

S000005951
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:493543-495246:1:exon

YPL029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPB2
gene: SUV3
locus tag: YPL029W
gene synonym: LPB2
so part of: sequence
location: <495506..>497719
location: region:495506-497719:1
so has part: feature:495506-497719:1:exon
subclass of: SO_0000010

856078
type: Gene
SIO_000068: ncbigene

position:495506:1
position: 495506
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:497719:1
position: 497719
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:495506-497719:1:exon

YPL029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPB2
gene: SUV3
locus tag: YPL029W
gene synonym: LPB2
product: ATP-dependent RNA helicase SUV3
transcript id: NM_001183843.1
SIO_010081: YPL029W
subclass of: SO_0000673
so part of: YPL029W
location: <495506..>497719
location: region:495506-497719:1
so has part: feature:495506-497719:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:495506-497719:1:exon

YPL029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPB2
gene: SUV3
locus tag: YPL029W
gene synonym: LPB2
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0000262 mitochondrial chromosome [PMID:21911497]
experiment: EXISTENCE:direct assay:GO:0003724 RNA helicase activity [PMID:12426313|PMID:17658549]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0008859 exoribonuclease II activity [PMID:17658549]
experiment: EXISTENCE:direct assay:GO:0045025 mitochondrial degradosome [PMID:12426313]
experiment: EXISTENCE:genetic interaction:GO:0000372 Group I intron splicing [PMID:20064926]
experiment: EXISTENCE:mutant phenotype:GO:0000957 mitochondrial RNA catabolic process [PMID:12426313]
experiment: EXISTENCE:mutant phenotype:GO:0006264 mitochondrial DNA replication [PMID:21911497]
note: ATP-dependent RNA helicase; component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron; expression of a processed form of human homolog SUPV3L1 carrying an N-terminal deletion of 46 amino acids rescues yeast suv3 null mutant
codon start: 1
product: ATP-dependent RNA helicase SUV3
translation: MALVKYSTVFFPLRSLRLFVSIKKAYYHSEPHSIDLFHDKDWIVKRPKFLNLPKNEHSKLDIFQFNFNKSESNNVYLQDSSFKDNLDKAMQFIYNDKLSSLDAKQVPIKNLAWLKLRDYIYQQLKDPKLQAKTYVPSVSEIIHPSSPGNLISLLINCNKISNLVWKSVLKYSLSNNITTLDKFIHVLQQTFDHVYEQEILPMMTNTDDTDGAHNVDITNPAEWFPEARKIRRHIIMHIGPTNSGKTYRALQKLKSVDRGYYAGPLRLLAREVYDRFHAEKIRCNLLTGEEVIRDLDDRGNSAGLTSGTVEMVPINQKFDVVVLDEIQMMSDGDRGWAWTNALLGVVSKEVHLCGEKSVLPLVKSIVKMTGDKLTINEYERLGKLSVEEKPIKDGIKGLRKGDCVVAFSKKKILDLKLKIEKDTNLKVAVIYGSLPPETRVQQAALFNNGEYDIMVASDAIGMGLNLSIDRVVFTTNMKYNGEELMEMTSSQIKQIGGRAGRFKSRSASGGVPQGFITSFESKVLKSVRKAIEAPVEYLKTAVTWPTDEICAQLMTQFPPGTPTSVLLQTISDELEKSSDNLFTLSDLKSKLKVIGLFEHMEDIPFFDKLKLSNAPVKDMPMVTKAFTKFCETIAKRHTRGLLSYRLPFNLLDYNCIPNESYSLEVYESLYNIITLYFWLSNRYPNYFIDMESAKDLKYFCEMIIFEKLDRLKKNPYAHKPFGSTRGHLSSSRRRLRT
SIO_010081: YPL029W
subclass of: SO_0000673
so part of: YPL029W
location: 495506..497719
location: region:495506-497719:1
so has part: feature:495506-497719:1:exon

NP_015296.1
type: Protein
SIO_000068: ncbiprotein

S000005950
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:495506-497719:1:exon

YPL028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPB3
alternative label: TSM0115
gene: ERG10
locus tag: YPL028W
gene synonym: LPB3; TSM0115
so part of: sequence
location: <498096..>499292
location: region:498096-499292:1
so has part: feature:498096-499292:1:exon
subclass of: SO_0000010

856079
type: Gene
SIO_000068: ncbigene

position:498096:1
position: 498096
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:499292:1
position: 499292
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:498096-499292:1:exon

YPL028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPB3
alternative label: TSM0115
gene: ERG10
locus tag: YPL028W
gene synonym: LPB3; TSM0115
product: acetyl-CoA C-acetyltransferase
transcript id: NM_001183842.1
SIO_010081: YPL028W
subclass of: SO_0000673
so part of: YPL028W
location: <498096..>499292
location: region:498096-499292:1
so has part: feature:498096-499292:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:498096-499292:1:exon

YPL028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPB3
alternative label: TSM0115
gene: ERG10
locus tag: YPL028W
gene synonym: LPB3; TSM0115
EC number: 2.3.1.9
experiment: EXISTENCE:direct assay:GO:0003985 acetyl-CoA C-acetyltransferase activity [PMID:7989303|PMID:5571829]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:5571830]
experiment: EXISTENCE:direct assay:GO:0006696 ergosterol biosynthetic process [PMID:5571829]
experiment: EXISTENCE:mutant phenotype:GO:0006696 ergosterol biosynthetic process [PMID:200835]
note: Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis; human ACAT1 functionally complements the growth defect caused by repression of ERG10 expression
codon start: 1
product: acetyl-CoA C-acetyltransferase
translation: MSQNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNVLSANLGQAPARQVALAAGLSNHIVASTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIEKI
SIO_010081: YPL028W
subclass of: SO_0000673
so part of: YPL028W
location: 498096..499292
location: region:498096-499292:1
so has part: feature:498096-499292:1:exon

NP_015297.1
type: Protein
SIO_000068: ncbiprotein

S000005949
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:498096-499292:1:exon

YPL027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMA1
locus tag: YPL027W
so part of: sequence
location: <499665..>500402
location: region:499665-500402:1
so has part: feature:499665-500402:1:exon
subclass of: SO_0000010

856080
type: Gene
SIO_000068: ncbigene

position:499665:1
position: 499665
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:500402:1
position: 500402
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:499665-500402:1:exon

YPL027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMA1
locus tag: YPL027W
product: Sma1p
transcript id: NM_001183841.1
SIO_010081: YPL027W
subclass of: SO_0000673
so part of: YPL027W
location: <499665..>500402
location: region:499665-500402:1
so has part: feature:499665-500402:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:499665-500402:1:exon

YPL027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMA1
locus tag: YPL027W
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:16148007|PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0032120 ascospore-type prospore membrane formation [PMID:16148007|PMID:11470404]
note: hypothetical protein involved in prospore membrane assembly; involved in the assembly of the prospore membrane during sporulation; interacts with Spo14p
codon start: 1
product: Sma1p
translation: MACTNDGPNKYPEIVSVKHLFQHSGSKHEFSAGKRFSKSIGKIFKRNSALKTSRTETANHKMELKKREGVTLLPPVPESLLHKLNSWLETFSSTKNMKIEENKIVINEKEIRDSVSYYPDKNGGSAVFCYLPDLVLYYKPPIKVTGKQCPIKRSPWESMEIQYQKFMYPLERLERQFEEVPFRPWYFAMRLKELYRCCERSFTNAANRGKARLLRGKQRTKKSYHKTVNLVSAKISTHSNAPSPG
SIO_010081: YPL027W
subclass of: SO_0000673
so part of: YPL027W
location: 499665..500402
location: region:499665-500402:1
so has part: feature:499665-500402:1:exon

NP_015298.1
type: Protein
SIO_000068: ncbiprotein

S000005948
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:499665-500402:1:exon

YPL026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SHA3
gene: SKS1
locus tag: YPL026C
gene synonym: SHA3
so part of: sequence
location: complement(<500675..>502183)
location: region:500675-502183:-1
so has part: feature:500675-502183:-1:exon
subclass of: SO_0000010

856081
type: Gene
SIO_000068: ncbigene

position:500675:-1
position: 500675
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:502183:-1
position: 502183
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:500675-502183:-1:exon

YPL026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SHA3
gene: SKS1
locus tag: YPL026C
gene synonym: SHA3
product: putative serine/threonine protein kinase SKS1
transcript id: NM_001183840.1
SIO_010081: YPL026C
subclass of: SO_0000673
so part of: YPL026C
location: complement(<500675..>502183)
location: region:500675-502183:-1
so has part: feature:500675-502183:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:500675-502183:-1:exon

YPL026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SHA3
gene: SKS1
locus tag: YPL026C
gene synonym: SHA3
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18417610]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:genetic interaction:GO:0009749 response to glucose [PMID:9559544]
experiment: EXISTENCE:genetic interaction:GO:0010827 regulation of glucose transmembrane transport [PMID:8948096]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:8948096]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:24603354]
note: Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication
codon start: 1
product: putative serine/threonine protein kinase SKS1
translation: MLSDCLLNNFRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGLNNNSQVARTTLLQTQLYHFFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLCDFGLSTKSKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFANDNNVLKKILPISDELFTVLTKILQLNPYTRIDMKTLMSEVSSLTSFTREGPLSQVPILSSEVYMTHIIRNENLFLSDLSHFSADQEQQQQQQQQQQQVQEQEQEQKQEQIQNQEQAQQQQEEEDAEPESDIPSTYNSDGSMEKYEYTNNHNNSTFLTSSMDSTPYQSDIDDVSASKDCKFQQDTLRNRLLCLQMNFSTLTDGPNEKWLPDY
SIO_010081: YPL026C
subclass of: SO_0000673
so part of: YPL026C
location: complement(500675..502183)
location: region:500675-502183:-1
so has part: feature:500675-502183:-1:exon

NP_015299.1
type: Protein
SIO_000068: ncbiprotein

S000005947
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:500675-502183:-1:exon

YPL024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NCE4
gene: RMI1
locus tag: YPL024W
gene synonym: NCE4
so part of: sequence
location: <503517..>504242
location: region:503517-504242:1
so has part: feature:503517-504242:1:exon
subclass of: SO_0000010

856083
type: Gene
SIO_000068: ncbigene

position:503517:1
position: 503517
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:504242:1
position: 504242
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:503517-504242:1:exon

YPL024W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NCE4
gene: RMI1
locus tag: YPL024W
gene synonym: NCE4
product: Rmi1p
transcript id: NM_001183838.1
SIO_010081: YPL024W
subclass of: SO_0000673
so part of: YPL024W
location: <503517..>504242
location: region:503517-504242:1
so has part: feature:503517-504242:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:503517-504242:1:exon

YPL024W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NCE4
gene: RMI1
locus tag: YPL024W
gene synonym: NCE4
experiment: EXISTENCE:direct assay:GO:0000400 four-way junction DNA binding [PMID:15899853]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:15899853]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006265 DNA topological change [PMID:22885009]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:17693398]
experiment: EXISTENCE:direct assay:GO:0031422 RecQ family helicase-topoisomerase III complex [PMID:15899853]
experiment: EXISTENCE:direct assay:GO:0043388 positive regulation of DNA binding [PMID:17693398]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:23036200]
experiment: EXISTENCE:genetic interaction:GO:0006974 cellular response to DNA damage stimulus [PMID:15889139]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:17571075]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:17571075|PMID:23036200]
experiment: EXISTENCE:physical interaction:GO:0031422 RecQ family helicase-topoisomerase III complex [PMID:15889139]
note: Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing, DNA catenation/decatenation and ssDNA binding activities of Top3p; involved in response to DNA damage; functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1p; stimulates Top3p DNA catenation/decatenation activity; null mutants display increased rates of recombination and delayed S phase
codon start: 1
product: Rmi1p
translation: MSFSSILSQDITDDITPPAYSATLGSREQIVFRAYQNEPWLAGTASNLILDKKLVIVDRELLFQVLMVENITKSKLTQIDDIKTKLDPKKQKVDRLRSGAQGNGAKKYEVITQVDMEDDGNVADNNCAKENNSNNNSSAAKNKAVFKLTLQSKSGDVFFAINSTPISWSSCMLGSKIVILPGTVFNRGVFILKDSQVIFLGGINRVWNENRDQKFCDYLESKLQRDKQLVNGGSKKRKAND
SIO_010081: YPL024W
subclass of: SO_0000673
so part of: YPL024W
location: 503517..504242
location: region:503517-504242:1
so has part: feature:503517-504242:1:exon

NP_015301.1
type: Protein
SIO_000068: ncbiprotein

S000005945
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:503517-504242:1:exon

YPL023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET12
locus tag: YPL023C
so part of: sequence
location: complement(<504339..>506312)
location: region:504339-506312:-1
so has part: feature:504339-506312:-1:exon
subclass of: SO_0000010

856084
type: Gene
SIO_000068: ncbigene

position:504339:-1
position: 504339
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:506312:-1
position: 506312
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:504339-506312:-1:exon

YPL023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET12
locus tag: YPL023C
product: methylenetetrahydrofolate reductase (NAD(P)H) MET12
transcript id: NM_001183837.1
SIO_010081: YPL023C
subclass of: SO_0000673
so part of: YPL023C
location: complement(<504339..>506312)
location: region:504339-506312:-1
so has part: feature:504339-506312:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:504339-506312:-1:exon

YPL023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET12
locus tag: YPL023C
EC number: 1.5.1.20
experiment: EXISTENCE:direct assay:GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity [PMID:10600168]
note: Protein with MTHFR activity in vitro; null mutant has no phenotype and is prototrophic for methionine; MET13 encodes major isozyme of methylenetetrahydrofolate reductase (MTHFR)
codon start: 1
product: methylenetetrahydrofolate reductase (NAD(P)H) MET12
translation: MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQSPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSLDSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA
SIO_010081: YPL023C
subclass of: SO_0000673
so part of: YPL023C
location: complement(504339..506312)
location: region:504339-506312:-1
so has part: feature:504339-506312:-1:exon

NP_015302.1
type: Protein
SIO_000068: ncbiprotein

S000005944
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:504339-506312:-1:exon

YPL022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPB9
alternative label: RAD12
gene: RAD1
locus tag: YPL022W
gene synonym: LPB9; RAD12
so part of: sequence
location: <506697..>509999
location: region:506697-509999:1
so has part: feature:506697-509999:1:exon
subclass of: SO_0000010

856085
type: Gene
SIO_000068: ncbigene

position:506697:1
position: 506697
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:509999:1
position: 509999
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:506697-509999:1:exon

YPL022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPB9
alternative label: RAD12
gene: RAD1
locus tag: YPL022W
gene synonym: LPB9; RAD12
product: ssDNA endodeoxyribonuclease RAD1
transcript id: NM_001183836.1
SIO_010081: YPL022W
subclass of: SO_0000673
so part of: YPL022W
location: <506697..>509999
location: region:506697-509999:1
so has part: feature:506697-509999:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:506697-509999:1:exon

YPL022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPB9
alternative label: RAD12
gene: RAD1
locus tag: YPL022W
gene synonym: LPB9; RAD12
experiment: EXISTENCE:direct assay:GO:0000014 single-stranded DNA endodeoxyribonuclease activity [PMID:8253764]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:8253764]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9852079]
experiment: EXISTENCE:direct assay:GO:0006289 nucleotide-excision repair [PMID:7559571]
experiment: EXISTENCE:mutant phenotype:GO:0000710 meiotic mismatch repair [PMID:11514439]
experiment: EXISTENCE:mutant phenotype:GO:0000735 removal of nonhomologous ends [PMID:1411547|PMID:7891718]
experiment: EXISTENCE:mutant phenotype:GO:0000736 double-strand break repair via single-strand annealing, removal of nonhomologous ends [PMID:7891718|PMID:1411547]
experiment: EXISTENCE:mutant phenotype:GO:0006277 DNA amplification [PMID:23271978]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:3065620]
experiment: EXISTENCE:physical interaction:GO:0000110 nucleotide-excision repair factor 1 complex [PMID:8621533]
note: Single-stranded DNA endonuclease (with Rad10p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
codon start: 1
product: ssDNA endodeoxyribonuclease RAD1
translation: MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVKDLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV
SIO_010081: YPL022W
subclass of: SO_0000673
so part of: YPL022W
location: 506697..509999
location: region:506697-509999:1
so has part: feature:506697-509999:1:exon

NP_015303.1
type: Protein
SIO_000068: ncbiprotein

S000005943
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:506697-509999:1:exon

YPL021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SRD2
gene: ECM23
locus tag: YPL021W
gene synonym: SRD2
so part of: sequence
location: <511101..>511664
location: region:511101-511664:1
so has part: feature:511101-511664:1:exon
subclass of: SO_0000010

856086
type: Gene
SIO_000068: ncbigene

position:511101:1
position: 511101
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:511664:1
position: 511664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:511101-511664:1:exon

YPL021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SRD2
gene: ECM23
locus tag: YPL021W
gene synonym: SRD2
product: Ecm23p
transcript id: NM_001183835.1
SIO_010081: YPL021W
subclass of: SO_0000673
so part of: YPL021W
location: <511101..>511664
location: region:511101-511664:1
so has part: feature:511101-511664:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:511101-511664:1:exon

YPL021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SRD2
gene: ECM23
locus tag: YPL021W
gene synonym: SRD2
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:11889490]
note: Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p
codon start: 1
product: Ecm23p
translation: MLYNKEQGTSGASSSGRRTKFHFDRFVQMVLFIAANPNYCCSVASIPKSGVTPDLKRADILEQKIKSLNSALSPKLKEESRLGGPLHNPSILPAPSFSSLPISSNGKKSLAGYRPKSRKKQTILPNGQPKECATCGDTWTSQWRSGPNGNVELCSRCGIAYRKKMEKKIRSQQSSDDGTKNFIFKNK
SIO_010081: YPL021W
subclass of: SO_0000673
so part of: YPL021W
location: 511101..511664
location: region:511101-511664:1
so has part: feature:511101-511664:1:exon

NP_015304.1
type: Protein
SIO_000068: ncbiprotein

S000005942
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:511101-511664:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1621; Autonomously Replicating Sequence
so part of: sequence
location: 511636..511793
location: region:511636-511793:1
so has part: feature:511636-511793:1:region

S000118417
type: SGD
SIO_000068: sgd

position:511636:1
position: 511636
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:511793:1
position: 511793
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:511636-511793:1:region

YPL020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NIB1
gene: ULP1
locus tag: YPL020C
gene synonym: NIB1
so part of: sequence
location: complement(<512313..>514178)
location: region:512313-514178:-1
so has part: feature:512313-514178:-1:exon
subclass of: SO_0000010

856087
type: Gene
SIO_000068: ncbigene

position:512313:-1
position: 512313
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:514178:-1
position: 514178
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:512313-514178:-1:exon

YPL020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NIB1
gene: ULP1
locus tag: YPL020C
gene synonym: NIB1
product: SUMO protease ULP1
transcript id: NM_001183834.1
SIO_010081: YPL020C
subclass of: SO_0000673
so part of: YPL020C
location: complement(<512313..>514178)
location: region:512313-514178:-1
so has part: feature:512313-514178:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:512313-514178:-1:exon

YPL020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NIB1
gene: ULP1
locus tag: YPL020C
gene synonym: NIB1
EC number: 3.4.22.68
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:10713161|PMID:20647537]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:20647537]
experiment: EXISTENCE:direct assay:GO:0008234 cysteine-type peptidase activity [PMID:10094048]
experiment: EXISTENCE:direct assay:GO:0016926 protein desumoylation [PMID:10094048]
experiment: EXISTENCE:direct assay:GO:0016929 deSUMOylase activity [PMID:10094048]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:12471376]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:10094048]
experiment: EXISTENCE:mutant phenotype:GO:0016926 protein desumoylation [PMID:10094048]
experiment: EXISTENCE:mutant phenotype:GO:0016929 deSUMOylase activity [PMID:10094048]
note: Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; contributes to regulation of telomeric silencing; sequestered to the nucleolus under stress conditions
codon start: 1
product: SUMO protease ULP1
translation: MSVEVDKHRNTLQYHKKNPYSPLFSPISTYRCYPRVLNNPSESRRSASFSGIYKKRTNTSRFNYLNDRRVLSMEESMKDGSDRASKAGFIGGIRETLWNSGKYLWHTFVKNEPRNFDGSEVEASGNSDVESRSSGSRSSDVPYGLRENYSSDTRKHKFDTSTWALPNKRRRIESEGVGTPSTSPISSLASQKSNCDSDNSITFSRDPFGWNKWKTSAIGSNSENNTSDQKNSYDRRQYGTAFIRKKKVAKQNINNTKLVSRAQSEEVTYLRQIFNGEYKVPKILKEERERQLKLMDMDKEKDTGLKKSIIDLTEKIKTILIENNKNRLQTRNENDDDLVFVKEKKISSLERKHKDYLNQKLKFDRSILEFEKDFKRYNEILNERKKIQEDLKKKKEQLAKKKLVPELNEKDDDQVQKALASRENTQLMNRDNIEITVRDFKTLAPRRWLNDTIIEFFMKYIEKSTPNTVAFNSFFYTNLSERGYQGVRRWMKRKKTQIDKLDKIFTPINLNQSHWALGIIDLKKKTIGYVDSLSNGPNAMSFAILTDLQKYVMEESKHTIGEDFDLIHLDCPQQPNGYDCGIYVCMNTLYGSADAPLDFDYKDAIRMRRFIAHLILTDALK
SIO_010081: YPL020C
subclass of: SO_0000673
so part of: YPL020C
location: complement(512313..514178)
location: region:512313-514178:-1
so has part: feature:512313-514178:-1:exon

NP_015305.1
type: Protein
SIO_000068: ncbiprotein

S000005941
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:512313-514178:-1:exon

YPL019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PHM2
gene: VTC3
locus tag: YPL019C
gene synonym: PHM2
so part of: sequence
location: complement(<514511..>517018)
location: region:514511-517018:-1
so has part: feature:514511-517018:-1:exon
subclass of: SO_0000010

856088
type: Gene
SIO_000068: ncbigene

position:514511:-1
position: 514511
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:517018:-1
position: 517018
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:514511-517018:-1:exon

YPL019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PHM2
gene: VTC3
locus tag: YPL019C
gene synonym: PHM2
product: vacuolar transporter chaperone
transcript id: NM_001183833.1
SIO_010081: YPL019C
subclass of: SO_0000673
so part of: YPL019C
location: complement(<514511..>517018)
location: region:514511-517018:-1
so has part: feature:514511-517018:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:514511-517018:-1:exon

YPL019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PHM2
gene: VTC3
locus tag: YPL019C
gene synonym: PHM2
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:11102525|PMID:11823419|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005516 calmodulin binding [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:genetic interaction:GO:0006797 polyphosphate metabolic process [PMID:11102525]
experiment: EXISTENCE:mutant phenotype:GO:0006797 polyphosphate metabolic process [PMID:11102525]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:11823419]
experiment: EXISTENCE:physical interaction:GO:0033254 vacuolar transporter chaperone complex [PMID:11823419]
note: Regulatory subunit of vacuolar transporter chaperone (VTC) complex; involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; important regulator of substrate invagination from the vacuolar membrane; targeted to vacuole via AP-3 pathway; VTC3 has a paralog, VTC2, that arose from the whole genome duplication
codon start: 1
product: vacuolar transporter chaperone
translation: MLFGIKLANDVYPPWKDSYIDYERLKKLLKESVIHDGRSSVDSWSERNESDFVEALDKELEKVYTFQISKYNAVLRKLDDLEENTKSAEKIQKINSEQFKNTLEECLDEAQRLDNFDRLNFTGFIKIVKKHDKLHPNYPSVKSLLQVRLKELPFNNSEEYSPLLYRISYLYEFLRSNYDHPNTVSKSLASTSKLSHFSNLEDASFKSYKFWVHDDNIMEVKARILRHLPALVYASVPNENDDFVDNLESDVRVQPEARLNIGSKSNSLSSDGNSNQDVEIGKSKSVIFPQSYDPTITTLYFDNDFFDLYNNRLLKISGAPTLRLRWIGKLLDKPDIFLEKRTFTENTETGNSSFEEIRLQMKAKFINNFIFKNDPSYKNYLINQLRERGTQKEELEKLSRDFDNIQNFIVEEKLQPVLRATYNRTAFQIPGDQSIRVTIDSNIMYIREDSLDKNRPIRNPENWHRDDIDSNIPNPLRFLRAGEYSKFPYSVMEIKVINQDNSQMPNYEWIKDLTNSHLVNEVPKFSLYLQGVASLFGEDDKYVNILPFWLPDLETDIRKNPQEAYEEEKKTLQKQKSIHDKLDNMRRLSKISVPDGKTTERQGQKDQNTRHVIADLEDHESSDEEGTALPKKSAVKKGKKFKTNAAFLKILAGKNISENGNDPYSDDTDSASSFQLPPGVKKPVHLLKNAGPVKVEAKVWLANERTFNRWLSVTTLLSVLTFSIYNSVQKAEFPQLADLLAYVYFFLTLFCGVWAYRTYLKRLTLIKGRSGKHLDAPVGPILVAVVLIVTLVVNFSVAFKEAARRERGLVNVSSQPSLPRTLKPIQDFIFNLVGE
SIO_010081: YPL019C
subclass of: SO_0000673
so part of: YPL019C
location: complement(514511..517018)
location: region:514511-517018:-1
so has part: feature:514511-517018:-1:exon

NP_015306.1
type: Protein
SIO_000068: ncbiprotein

S000005940
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:514511-517018:-1:exon

YPL018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MCM18
gene: CTF19
locus tag: YPL018W
gene synonym: MCM18
so part of: sequence
location: <517651..>518760
location: region:517651-518760:1
so has part: feature:517651-518760:1:exon
subclass of: SO_0000010

856089
type: Gene
SIO_000068: ncbigene

position:517651:1
position: 517651
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:518760:1
position: 518760
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:517651-518760:1:exon

YPL018W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MCM18
gene: CTF19
locus tag: YPL018W
gene synonym: MCM18
product: Ctf19p
transcript id: NM_001183832.1
SIO_010081: YPL018W
subclass of: SO_0000673
so part of: YPL018W
location: <517651..>518760
location: region:517651-518760:1
so has part: feature:517651-518760:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:517651-518760:1:exon

YPL018W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MCM18
gene: CTF19
locus tag: YPL018W
gene synonym: MCM18
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:10189365]
experiment: EXISTENCE:direct assay:GO:0000817 COMA complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10189365]
experiment: EXISTENCE:direct assay:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:10189365]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:10189365]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:22426531]
experiment: EXISTENCE:mutant phenotype:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:10189365]
experiment: EXISTENCE:mutant phenotype:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:19730685]
experiment: EXISTENCE:mutant phenotype:GO:0071459 protein localization to chromosome, centromeric region [PMID:26653857]
note: Outer kinetochore protein, needed for accurate chromosome segregation; component of kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as platform for kinetochore assembly; required for spindle assembly checkpoint; minimizes potentially deleterious centromere-proximal crossovers by preventing meiotic DNA break formation proximal to centromere; homolog of human centromere constitutive-associated network (CCAN) subunit CENP-P and fission yeast fta2
codon start: 1
product: Ctf19p
translation: MDFTSDTTNSHDTSNSHLSLEDAVGTHHAGEADVNIDGDEKQQLSLLDDDQVRALKLQEEKDALLTRRNTLLQEIQTYQNILMKENNSKTKNGDILQNDITQDFLNLISISSSNPNSAISDRKRVERINGLTNLQKELVTKYDTLPLLNMNLRLSYLRDHTYPHLQVSVQSRDRVHNDGIEVLVVNYKFCRNTMNPFEIQFKMFYKFEDSTLLKWEILRISTNVRLKAKQLLATRNFQKCLLSLYEFDKIKSKKTGIFQNLINLLKRKTRCYLMNNSDSLIVERVIREGRLTTIKLQINFIITMPGERGKPRNCFLPMSKISIALWKGGERFNQIDLDEICYGLIKEYGVKTGLKEICNVCLFPDMYAR
SIO_010081: YPL018W
subclass of: SO_0000673
so part of: YPL018W
location: 517651..518760
location: region:517651-518760:1
so has part: feature:517651-518760:1:exon

NP_015307.1
type: Protein
SIO_000068: ncbiprotein

S000005939
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:517651-518760:1:exon

YPL017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC15
locus tag: YPL017C
so part of: sequence
location: complement(<518734..>520233)
location: region:518734-520233:-1
so has part: feature:518734-520233:-1:exon
subclass of: SO_0000010

856090
type: Gene
SIO_000068: ncbigene

position:518734:-1
position: 518734
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:520233:-1
position: 520233
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:518734-520233:-1:exon

YPL017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC15
locus tag: YPL017C
product: Irc15p
transcript id: NM_001183831.1
SIO_010081: YPL017C
subclass of: SO_0000673
so part of: YPL017C
location: complement(<518734..>520233)
location: region:518734-520233:-1
so has part: feature:518734-520233:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:518734-520233:-1:exon

YPL017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC15
locus tag: YPL017C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005874 microtubule [PMID:19285398]
experiment: EXISTENCE:direct assay:GO:0007020 microtubule nucleation [PMID:19285398]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:19285398]
experiment: EXISTENCE:direct assay:GO:0016651 oxidoreductase activity, acting on NAD(P)H [PMID:30267443]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:18085829]
experiment: EXISTENCE:mutant phenotype:GO:0034453 microtubule anchoring [PMID:19285398]
experiment: EXISTENCE:mutant phenotype:GO:0045144 meiotic sister chromatid segregation [PMID:18069899]
experiment: EXISTENCE:mutant phenotype:GO:0045931 positive regulation of mitotic cell cycle [PMID:19285398]
experiment: EXISTENCE:mutant phenotype:GO:0051315 attachment of mitotic spindle microtubules to kinetochore [PMID:19285398]
note: Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci; IRC15 has a paralog, LPD1, that arose from the whole genome duplication
codon start: 1
product: Irc15p
translation: MGGEDEILSTMEDFAAVYDVLVIGCGPGGFTAAMQASQAGLLTACVDQRASLGGAYLVDGAVPSKTLLYESYLYRLLQQQELIEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFKDPHHVEIAQRGMKPFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLDTRVQLAEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIGLDERDFVENVDVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYCQPQIGWVGYTEEGLAKARIPYQKGRVLFSQNVRYNTLLPREENTTVSPFIKVLIDSRDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANGTSPGVHVRE
SIO_010081: YPL017C
subclass of: SO_0000673
so part of: YPL017C
location: complement(518734..520233)
location: region:518734-520233:-1
so has part: feature:518734-520233:-1:exon

NP_015308.1
type: Protein
SIO_000068: ncbiprotein

S000005938
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:518734-520233:-1:exon

YPL016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ADR6
alternative label: GAM3
alternative label: LPA1
gene: SWI1
locus tag: YPL016W
gene synonym: ADR6; GAM3; LPA1
so part of: sequence
location: <521014..>524958
location: region:521014-524958:1
so has part: feature:521014-524958:1:exon
subclass of: SO_0000010

856091
type: Gene
SIO_000068: ncbigene

position:521014:1
position: 521014
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:524958:1
position: 524958
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:521014-524958:1:exon

YPL016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ADR6
alternative label: GAM3
alternative label: LPA1
gene: SWI1
locus tag: YPL016W
gene synonym: ADR6; GAM3; LPA1
product: Swi1p
transcript id: NM_001183830.2
SIO_010081: YPL016W
subclass of: SO_0000673
so part of: YPL016W
location: <521014..>524958
location: region:521014-524958:1
so has part: feature:521014-524958:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:521014-524958:1:exon

YPL016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ADR6
alternative label: GAM3
alternative label: LPA1
gene: SWI1
locus tag: YPL016W
gene synonym: ADR6; GAM3; LPA1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:3143101]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:8016655]
experiment: EXISTENCE:direct assay:GO:0016514 SWI/SNF complex [PMID:18644858|PMID:8016655|PMID:8127913|PMID:8159677]
experiment: EXISTENCE:genetic interaction:GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter [PMID:14580348]
experiment: EXISTENCE:mutant phenotype:GO:0006261 DNA-templated DNA replication [PMID:10198436]
experiment: EXISTENCE:mutant phenotype:GO:0016514 SWI/SNF complex [PMID:8159677]
experiment: EXISTENCE:mutant phenotype:GO:0031496 positive regulation of mating type switching [PMID:6436497]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:1339306|PMID:3542227|PMID:8016655|PMID:10549298]
experiment: EXISTENCE:mutant phenotype:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:14580348]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:11865042|PMID:14580348]
note: Subunit of the SWI/SNF chromatin remodeling complex; regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; self-assembles to form [SWI+] prion and to alter expression pattern; human homolog ARID1A is a candidate tumor suppressor gene in breast cancer
codon start: 1
product: Swi1p
translation: MDFFNLNNNNNNNNTTTTTTTTNNNNTNNNNTNNNNNPANNTNNNNSTGHSSNTNNNTNNNNTNTGASGVDDFQNFFDPKPFDQNLDSNNNNSNSNNNDNNNSNTVASSTNFTSPTAVVNNAAPANVTGGKAANFIQNQSPQFNSPYDSNNSNTNLNSLSPQAILAKNSIIDSSNLPLQAQQQLYGGNNNNNSTGIANDNVITPHFITNVQSISQNSSSSTPNTNSNSTPNANQQFLPFNNSASNNGNLTSNQLISNYAASNSMDRSSSASNEFVPNTSDNNNNSNNHNMRNNSNNKTSNNNNVTAVPAATPANTNNSTSNANTVFSERAAMFAALQQKQQQRFQALQQQQQQQQNQQQQNQQPQQQQQQQQNPKFLQSQRQQQQRSILQSLNPALQEKISTELNNKQYELFMKSLIENCKKRNMPLQSIPEIGNRKINLFYLYMLVQKFGGADQVTRTQQWSMVAQRLQISDYQQLESIYFRILLPYERHMISQEGIKETQAKRIFLQQFLQELLKKVQQQQQAAALANANNNINSASSAPTPAAPGASVPATAAPGTEAGIVPVSANTPKSLNSNININVNNNNIGQQQVKKPRKQRVKKKTKKELELERKEREDFQKRQQKLLEDQQRQQKLLLETKLRQQYEIELKKLPKVYKRSIVRNYKPLINRLKHYNGYDINYISKIGEKIDSNKPIFLFAPELGAINLHALSMSLQSKNLGEINTALNTLLVTSADSNLKISLVKYPELLDSLAILGMNLLSNLSQNVVPYHRNTSDYYYEDAGSNQYYVTQHDKMVDKIFEKVNNNATLTPNDSNDEKVTILVDSLTGNQLPTPTPTEMEPDLDTECFISMQSTSPAVKQWDLLPEPIRFLPNQFPLKIHRTPYLTSLKKIKDEIDDPFTKINTRGAEDPKVLINDQLSTISMILRNISFSDNNSRIMSRNFYLKRFISDLLWLVLIHPENFTCNRKILNFKKDLVIVLSNISHLLEIASSIDCLLILILVISFGQPKLNPMASSSSFGSESLTFNEFQLQWGKYQTFGVDILAKLFSLEKPNLNYFKSILLNKNTGNNLYDRNSNNNHKDKKLLRRLLNLYNDNNKNNNNRHNLLNDVVSFLFSAIPLQQVLSQSADPSLLIDQFSPVISQSLTSILVIVQKILPLSNEVFEISENNSDSNSNNNGNKDSSFNFNKNLPFVWLSSEENIGSGLLKLSEIILNINNSTSKNTLLQQQNYSKVLLPSINISCVQLIKCLVEKSICFENCLNNDPEILKKIASIPNLFPTDLEIFQLFTNPSVDIQIINQYQLLYNLKNDILTNLE
SIO_010081: YPL016W
subclass of: SO_0000673
so part of: YPL016W
location: 521014..524958
location: region:521014-524958:1
so has part: feature:521014-524958:1:exon

NP_015309.1
type: Protein
SIO_000068: ncbiprotein

S000005937
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:521014-524958:1:exon

YPL015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HST2
locus tag: YPL015C
so part of: sequence
location: complement(<525810..>526883)
location: region:525810-526883:-1
so has part: feature:525810-526883:-1:exon
subclass of: SO_0000010

856092
type: Gene
SIO_000068: ncbigene

position:525810:-1
position: 525810
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:526883:-1
position: 526883
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:525810-526883:-1:exon

YPL015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HST2
locus tag: YPL015C
product: histone deacetylase HST2
transcript id: NM_001183829.1
SIO_010081: YPL015C
subclass of: SO_0000673
so part of: YPL015C
location: complement(<525810..>526883)
location: region:525810-526883:-1
so has part: feature:525810-526883:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:525810-526883:-1:exon

YPL015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HST2
locus tag: YPL015C
EC number: 2.3.1.286
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17110954]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11226170]
experiment: EXISTENCE:direct assay:GO:0017136 NAD-dependent histone deacetylase activity [PMID:10811920]
experiment: EXISTENCE:genetic interaction:GO:0045950 negative regulation of mitotic recombination [PMID:16051752]
experiment: EXISTENCE:mutant phenotype:GO:0000183 rDNA heterochromatin formation [PMID:11226170|PMID:16051752]
experiment: EXISTENCE:mutant phenotype:GO:0017136 NAD-dependent histone deacetylase activity [PMID:10841563]
experiment: EXISTENCE:mutant phenotype:GO:0045950 negative regulation of mitotic recombination [PMID:16051752]
note: Cytoplasmic NAD(+)-dependent protein deacetylase; deacetylation targets are primarily cytoplasmic proteins; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export
codon start: 1
product: histone deacetylase HST2
translation: MSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE
SIO_010081: YPL015C
subclass of: SO_0000673
so part of: YPL015C
location: complement(525810..526883)
location: region:525810-526883:-1
so has part: feature:525810-526883:-1:exon

NP_015310.1
type: Protein
SIO_000068: ncbiprotein

S000005936
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:525810-526883:-1:exon

YPL014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CIP1
locus tag: YPL014W
so part of: sequence
location: <527547..>528692
location: region:527547-528692:1
so has part: feature:527547-528692:1:exon
subclass of: SO_0000010

856093
type: Gene
SIO_000068: ncbigene

position:527547:1
position: 527547
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:528692:1
position: 528692
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:527547-528692:1:exon

YPL014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CIP1
locus tag: YPL014W
product: Cip1p
transcript id: NM_001183828.1
SIO_010081: YPL014W
subclass of: SO_0000673
so part of: YPL014W
location: <527547..>528692
location: region:527547-528692:1
so has part: feature:527547-528692:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:527547-528692:1:exon

YPL014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CIP1
locus tag: YPL014W
experiment: EXISTENCE:direct assay:GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity [PMID:27005485]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:27005485]
experiment: EXISTENCE:mutant phenotype:GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:27005485]
note: Cyclin-dependent kinase inhibitor; activated by environmental stress; interacts with and inhibits the Cdc28p/Cln2p, G1/S phase cyclin-dependent kinase complex but not S-phase, or M-phase complexes; overexpression blocks cells in G1 phase and stabilizes the Cdc28p inhibitor Sic1p, while disruption accelerates the G1/S phase transition; phosphorylated during S phase in a Cdc28p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
codon start: 1
product: Cip1p
translation: MLLERLHKRLHAGSSRRSQENKDKNCKPEDALPIQPEAQHQTQDPQPLLNCDYDDMIAFDRNLSTPVFTPVMTPINNSSSNQAKSSDASYFPPYLNANRTRQNSASSLASSVSDFAQNFKQHTFYNNNAQFTSFTPQFVGLLLEVYQNTCSDPTITPFDTTNPPSGILNRVAKAAIQQSELQQLDIGCDRNSWLLTLVRQRLLQEVRKDGYLSRNTSLTSLPPPPPPQFSEMLRVPSPFVNADITDPIPLSNTNSNPNVSSTTSLTNTLNWYSLQRSNVSMKNRNGSSQYISELQPQPILARTNSNNSVSNSNAFSLLTPTPTTDSAFNFNIALLSRQRSNIISSPLASTRLPTANVSTEESSILPNESLKLKRDLLRLKR
SIO_010081: YPL014W
subclass of: SO_0000673
so part of: YPL014W
location: 527547..528692
location: region:527547-528692:1
so has part: feature:527547-528692:1:exon

NP_015311.1
type: Protein
SIO_000068: ncbiprotein

S000005935
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:527547-528692:1:exon

YPL013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bS16m
gene: MRPS16
locus tag: YPL013C
gene synonym: bS16m
so part of: sequence
location: complement(<528985..>529350)
location: region:528985-529350:-1
so has part: feature:528985-529350:-1:exon
subclass of: SO_0000010

856094
type: Gene
SIO_000068: ncbigene

position:528985:-1
position: 528985
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:529350:-1
position: 529350
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:528985-529350:-1:exon

YPL013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bS16m
gene: MRPS16
locus tag: YPL013C
gene synonym: bS16m
product: mitochondrial 37S ribosomal protein MRPS16
transcript id: NM_001183827.1
SIO_010081: YPL013C
subclass of: SO_0000673
so part of: YPL013C
location: complement(<528985..>529350)
location: region:528985-529350:-1
so has part: feature:528985-529350:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:528985-529350:-1:exon

YPL013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bS16m
gene: MRPS16
locus tag: YPL013C
gene synonym: bS16m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:12392552]
note: Mitochondrial ribosomal protein of the small subunit
codon start: 1
product: mitochondrial 37S ribosomal protein MRPS16
translation: MTCGLVRIRLARFGRKNSPVYNIVVANSRKARDAKPIEVLGTYVPVPSPVTKRELKRGVVPIKDVKLDFDRTKYWIGVGAQPSETVTKLLRKAGILNDAWATSKNSNVNRKVVFERMETLE
SIO_010081: YPL013C
subclass of: SO_0000673
so part of: YPL013C
location: complement(528985..529350)
location: region:528985-529350:-1
so has part: feature:528985-529350:-1:exon

NP_015312.1
type: Protein
SIO_000068: ncbiprotein

S000005934
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:528985-529350:-1:exon

YPL012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRP12
locus tag: YPL012W
so part of: sequence
location: <529723..>533409
location: region:529723-533409:1
so has part: feature:529723-533409:1:exon
subclass of: SO_0000010

856095
type: Gene
SIO_000068: ncbigene

position:529723:1
position: 529723
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:533409:1
position: 533409
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:529723-533409:1:exon

YPL012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRP12
locus tag: YPL012W
product: mRNA-binding protein RRP12
transcript id: NM_001183826.1
SIO_010081: YPL012W
subclass of: SO_0000673
so part of: YPL012W
location: <529723..>533409
location: region:529723-533409:1
so has part: feature:529723-533409:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:529723-533409:1:exon

YPL012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRP12
locus tag: YPL012W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14729571]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:15167894]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:12089522]
note: Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; has a role in nuclear import in association with Pse1p; also plays a role in the cell cycle and the DNA damage response; contains HEAT-repeats
codon start: 1
product: mRNA-binding protein RRP12
translation: MDQDKVAFLLELEDKLAKIRSQVNSKLENQKHIAIILTAVEENIAGQATNDVSKNIVNYIISFMSLLDQAVDPSTHEIKDIQLASSSTYLLDLIFHYSPKVLLRSKFSEILTKIAPCITAEKANAPLIRAAIGCLESLLIAQDAQAWNNTYDLNVTPKRGLQGILELSLDVRPKVRKRALDAVHAVLLNPPVAPTAEHVAAVFVADFCDKQLAGILNDLSNLSNKQLKAQKTKEDINASVMRSLRLITSVVSTGQWPSSQIEPLCDVLLGVTKSSEQYLVSASFECFESMFKTMAETTISSGLAENKYLRVLDTIFALKPSNVDTLLTKSWIAVVIKGMSTYATHQPLKALRKIPGVFHIMCTYLASETPEVYQAASQCLISILSESVKDDLLLYTPSVDEKVFKNVDEIISQIAKTFIDFLSIRYSHCSREILKILVAAFNKFRYRSNPHFLKSLKIVDTWRVNEEQFMDLRNEIELVIGASISAMGPEMILAEAPLNLDNPSSERPGRAWLLPLIRDYTKNANLATFQNELAPYIKSFQSKFDKVPEESIQLRVFQTIVDQIWSTLPRFCELPMDLRESFTDEFASELSSLLYSEVELRTTICHALKVLAESNVSYAEESSSHNVLLLQRFPISEAQKNIEYLSTKSTNLLAVLFNVYTQTTPNARSYILETIDQYLKITSKEDLEKTFNNVCGLLKNSMNEESSGNVNKEKKKPQLTATLLDLIICMITYLPVSSYSALFSMFSLTVNSADALIQKRAYRIITKLSELKSGSTAVAQFISDIENVMVDSASSVQTSAKAARLTAIKTIVELLPLDHLDFIVRTVAEVILSTKDVNEKSRETAFDTLICMGRKMNEPNGIIKLFQIPGYDPTTPDQSSSISEFFKIISAGLIGESQHMVSSSITGYACLVFEFKNELDSGILMDIYDTIELYLTSNSREIVKSAIGFTKVCVLGLPEELMRPKVPELLLKLLRWSHEHTGHFKAKVKHIIERLIRRFGYDYIEANFPEEDRRLLTNIRKMRNRNKRKDEEVTTGVSDVAATKGSRFMSAFDEAVYGSDEENDNGSDQEENVAGGKMKNGAKQFIVESGDNPLDLLDSQTLAHISSTRPKKFNKNQNRARFNDDAFNFDSEGKLVVKGQPKPSTNVDDPLSAVTSGINAYLEAVKSGPVRGQRNKLKFRKNGKDSDEFGDDDDGEKDSRLMRGRVNQGNKIGKHNKKGPKFKSRKKL
SIO_010081: YPL012W
subclass of: SO_0000673
so part of: YPL012W
location: 529723..533409
location: region:529723-533409:1
so has part: feature:529723-533409:1:exon

NP_015313.1
type: Protein
SIO_000068: ncbiprotein

S000005933
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:529723-533409:1:exon

YPL011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAF47
gene: TAF3
locus tag: YPL011C
gene synonym: TAF47
so part of: sequence
location: complement(<533642..>534703)
location: region:533642-534703:-1
so has part: feature:533642-534703:-1:exon
subclass of: SO_0000010

856096
type: Gene
SIO_000068: ncbigene

position:533642:-1
position: 533642
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:534703:-1
position: 534703
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:533642-534703:-1:exon

YPL011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAF47
gene: TAF3
locus tag: YPL011C
gene synonym: TAF47
product: Taf3p
transcript id: NM_001183825.1
SIO_010081: YPL011C
subclass of: SO_0000673
so part of: YPL011C
location: complement(<533642..>534703)
location: region:533642-534703:-1
so has part: feature:533642-534703:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:533642-534703:-1:exon

YPL011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAF47
gene: TAF3
locus tag: YPL011C
gene synonym: TAF47
experiment: EXISTENCE:curator inference:GO:0016251 RNA polymerase II general transcription initiation factor activity [PMID:15448131]
experiment: EXISTENCE:curator inference:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:10788514]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:17660549]
experiment: EXISTENCE:direct assay:GO:0005669 transcription factor TFIID complex [PMID:15448131|PMID:10788514]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:12138208|PMID:15448131]
note: TFIID subunit (47 kDa); involved in promoter binding and RNA polymerase II transcription initiation
codon start: 1
product: Taf3p
translation: MTTNNDFYFALLRISILQLLKAQGFDRARPSLVDVMTDLYAKFLSLLASEVSSIAQARCDQDDTIALQDITLALENLGIVKPTNVLDVYDENSELSSSRGMEKFKDWCIYSTQLTDARITALPTVELLQSEEKESDPLSAIPDYLNQLLQNKGAKQKLETKNRKTELIEDLINNNGLDDWIKLVIARQRINMIERASKKESQNVPALPHIAGYKSSILSRHHHTTITNEDRMPSAMTPRDEDALTEIQENPFVTSKLPIMRKENRLENITLSFEDEELESLGEVEGPNQKSQENNNEESFKENNKSLTESPHGDDRDISMFQFDSNVDTKWAEQEDMDSTFQRRTSLDYGGYF
SIO_010081: YPL011C
subclass of: SO_0000673
so part of: YPL011C
location: complement(533642..534703)
location: region:533642-534703:-1
so has part: feature:533642-534703:-1:exon

NP_015314.1
type: Protein
SIO_000068: ncbiprotein

S000005932
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:533642-534703:-1:exon

YPL010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RET3
locus tag: YPL010W
so part of: sequence
location: <535018..>535587
location: region:535018-535587:1
so has part: feature:535018-535587:1:exon
subclass of: SO_0000010

856097
type: Gene
SIO_000068: ncbigene

position:535018:1
position: 535018
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:535587:1
position: 535587
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:535018-535587:1:exon

YPL010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RET3
locus tag: YPL010W
product: coatomer subunit zeta
transcript id: NM_001183824.1
SIO_010081: YPL010W
subclass of: SO_0000673
so part of: YPL010W
location: <535018..>535587
location: region:535018-535587:1
so has part: feature:535018-535587:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:535018-535587:1:exon

YPL010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RET3
locus tag: YPL010W
experiment: EXISTENCE:direct assay:GO:0030126 COPI vesicle coat [PMID:21435344]
experiment: EXISTENCE:mutant phenotype:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:8617224]
experiment: EXISTENCE:mutant phenotype:GO:0030126 COPI vesicle coat [PMID:8617224]
note: Zeta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
codon start: 1
product: coatomer subunit zeta
translation: MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL
SIO_010081: YPL010W
subclass of: SO_0000673
so part of: YPL010W
location: 535018..535587
location: region:535018-535587:1
so has part: feature:535018-535587:1:exon

NP_015315.1
type: Protein
SIO_000068: ncbiprotein

S000005931
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:535018-535587:1:exon

YPL009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAE2
gene: RQC2
locus tag: YPL009C
gene synonym: TAE2
so part of: sequence
location: complement(<535820..>538936)
location: region:535820-538936:-1
so has part: feature:535820-538936:-1:exon
subclass of: SO_0000010

856098
type: Gene
SIO_000068: ncbigene

position:535820:-1
position: 535820
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:538936:-1
position: 538936
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:535820-538936:-1:exon

YPL009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAE2
gene: RQC2
locus tag: YPL009C
gene synonym: TAE2
product: Rqc2p
transcript id: NM_001183823.1
SIO_010081: YPL009C
subclass of: SO_0000673
so part of: YPL009C
location: complement(<535820..>538936)
location: region:535820-538936:-1
so has part: feature:535820-538936:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:535820-538936:-1:exon

YPL009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAE2
gene: RQC2
locus tag: YPL009C
gene synonym: TAE2
experiment: EXISTENCE:direct assay:GO:0000049 tRNA binding [PMID:25554787]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:23222640|PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0043023 ribosomal large subunit binding [PMID:25554787]
experiment: EXISTENCE:direct assay:GO:1990112 RQC complex [PMID:23178123]
experiment: EXISTENCE:genetic interaction:GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process [PMID:23479637]
experiment: EXISTENCE:mutant phenotype:GO:0043043 peptide biosynthetic process [PMID:25554787]
experiment: EXISTENCE:mutant phenotype:GO:0072344 rescue of stalled ribosome [PMID:26943317]
experiment: EXISTENCE:mutant phenotype:GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process [PMID:23479637]
experiment: EXISTENCE:physical interaction:GO:1990112 RQC complex [PMID:23479637]
note: Component of the Ribosome Quality Control (RQC) complex; RQC is a ribosome-bound complex required for degradation of polypeptides arising from stalled translation; recruits alanine- and threonine-charged tRNA to the A site and directs the elongation of nascent chains independently of mRNA or 40S subunits; monitors translation stress and signals this to Hsf1p
codon start: 1
product: Rqc2p
translation: MKQRISALDLLLLARELKQDLEGYRLSNIYNIADSSKQFLLKFNKPDSKLNVVVDCGLRIYLTEFSRPIPPTPSGFVVKLRKHLKAKRLTALKQVDQDRILVLQFADGHFYLVLEFFSAGNVILLDENRRIMALQRVVLEHENKVGQIYEMFDESLFTTNNESADESIEKNRKAEYTSELVNEWIKAVQAKYESDITVIKQLNIQGKEGAKKKKVKVPSIHKLLLSKVPHLSSDLLSKNLKVFNIDPSESCLNLLEETDSLAELLNSTQLEYNQLLTTTDRKGYILAKRNENYISEKDTADLEFIYDTFHPFKPYINGGDTDSSCIIEVEGPYNRTLDKFFSTIESSKYALRIQNQESQAQKKIDDARAENDRKIQALLDVQELNERKGHLIIENAPLIEEVKLAVQGLIDQQMDWNTIEKLIKSEQKKGNRIAQLLNLPLNLKQNKISVKLDLSSKELNTSSDEDNESEGNTTDSSSDSDSEDMESSKERSTKSMKRKSNEKINVTIDLGLSAYANATEYFNIKKTSAQKQKKVEKNVGKAMKNIEVKIDQQLKKKLKDSHSVLKKIRTPYFFEKYSWFISSEGFLVMMGKSPAETDQIYSKYIEDDDIYMSNSFNSHVWIKNPEKTEVPPNTLMQAGILCMSSSEAWSKKISSSPWWCFAKNVSKFDGSDNSILPEGAFRLKNENDQNHLPPAQLVMGFGFLWKVKTSGNEDNGDDDEEEEEEEEEEEEEEEEEEEEEEEEKEEEEKEEEQQQDEDDSNEVNGLEKGGDSNDSTKNNSFEHDNLEKDIEKHCTISSDTDSDSGNAKAKNDNSSTQRILDEPGVPISLIENINSNVRGKRGKLKKIQKKYADQDETERLLRLEALGTLKGIEKQQQRKKEEIMKREVREDRKNKREKQRRLQALKFTKKEKARVNYDKHKSELKPSLDKGDVVDDIIPVFAPWPALLKYKYKVKIQPGSAKKTKTLTEILHYFKSRPLDGSSTDNEMDWPQEHEMIKGLKEQDLVLLLCVDKLKVTIAGQKSTKNGGNSSKKGKKKR
SIO_010081: YPL009C
subclass of: SO_0000673
so part of: YPL009C
location: complement(535820..538936)
location: region:535820-538936:-1
so has part: feature:535820-538936:-1:exon

NP_015316.1
type: Protein
SIO_000068: ncbiprotein

S000005930
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:535820-538936:-1:exon

YPL008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CTF1
alternative label: LPA9
alternative label: MCM12
gene: CHL1
locus tag: YPL008W
gene synonym: CTF1; LPA9; MCM12
so part of: sequence
location: <539385..>541970
location: region:539385-541970:1
so has part: feature:539385-541970:1:exon
subclass of: SO_0000010

856099
type: Gene
SIO_000068: ncbigene

position:539385:1
position: 539385
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:541970:1
position: 541970
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:539385-541970:1:exon

YPL008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CTF1
alternative label: LPA9
alternative label: MCM12
gene: CHL1
locus tag: YPL008W
gene synonym: CTF1; LPA9; MCM12
product: DNA helicase
transcript id: NM_001183822.1
SIO_010081: YPL008W
subclass of: SO_0000673
so part of: YPL008W
location: <539385..>541970
location: region:539385-541970:1
so has part: feature:539385-541970:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:539385-541970:1:exon

YPL008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CTF1
alternative label: LPA9
alternative label: MCM12
gene: CHL1
locus tag: YPL008W
gene synonym: CTF1; LPA9; MCM12
EC number: 3.6.4.12
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:14742714|PMID:15020404|PMID:17483413]
experiment: EXISTENCE:genetic interaction:GO:0036297 interstrand cross-link repair [PMID:22912599]
experiment: EXISTENCE:mutant phenotype:GO:0000785 chromatin [PMID:24086532]
experiment: EXISTENCE:mutant phenotype:GO:0003678 DNA helicase activity [PMID:10931920]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:15020404|PMID:14742714]
experiment: EXISTENCE:mutant phenotype:GO:0031571 mitotic G1 DNA damage checkpoint signaling [PMID:34493312]
experiment: EXISTENCE:mutant phenotype:GO:0034085 establishment of sister chromatid cohesion [PMID:23334284]
experiment: EXISTENCE:physical interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:15020404]
note: Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome
codon start: 1
product: DNA helicase
translation: MDKKEYSETFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEINTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPVKIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRHSKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQALKEEESSKNENPIKETHKKSVSSQPLLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLLPEVPSEDITTLSCNHVIPKENLQTYITNQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDDILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRYNRPNFRKKLSRWVQDSINSEHTTHQVISSTRKFFSMRSLNSR
SIO_010081: YPL008W
subclass of: SO_0000673
so part of: YPL008W
location: 539385..541970
location: region:539385-541970:1
so has part: feature:539385-541970:1:exon

NP_015317.1
type: Protein
SIO_000068: ncbiprotein

S000005929
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:539385-541970:1:exon

YPL007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TFC8
locus tag: YPL007C
so part of: sequence
location: complement(<542082..>543848)
location: region:542082-543848:-1
so has part: feature:542082-543848:-1:exon
subclass of: SO_0000010

856100
type: Gene
SIO_000068: ncbigene

position:542082:-1
position: 542082
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:543848:-1
position: 543848
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:542082-543848:-1:exon

YPL007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TFC8
locus tag: YPL007C
product: transcription factor TFIIIC subunit TFC8
transcript id: NM_001183821.1
SIO_010081: YPL007C
subclass of: SO_0000673
so part of: YPL007C
location: complement(<542082..>543848)
location: region:542082-543848:-1
so has part: feature:542082-543848:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:542082-543848:-1:exon

YPL007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TFC8
locus tag: YPL007C
experiment: EXISTENCE:direct assay:GO:0000127 transcription factor TFIIIC complex [PMID:10567530|PMID:2002052|PMID:1474578]
experiment: EXISTENCE:direct assay:GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding [PMID:2404611|PMID:2649882]
experiment: EXISTENCE:direct assay:GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding [PMID:2404611]
experiment: EXISTENCE:direct assay:GO:0006383 transcription by RNA polymerase III [PMID:3633923|PMID:8464480|PMID:2183033]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:2002052]
experiment: EXISTENCE:direct assay:GO:0042791 5S class rRNA transcription by RNA polymerase III [PMID:2183033]
experiment: EXISTENCE:genetic interaction:GO:0006383 transcription by RNA polymerase III [PMID:10567530]
experiment: EXISTENCE:mutant phenotype:GO:0006383 transcription by RNA polymerase III [PMID:10567530]
note: Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90
codon start: 1
product: transcription factor TFIIIC subunit TFC8
translation: MKLLKDLLVDRKEFEDWKNNLTWARDGTLYLTTFPDISIGQPKYAKDINCNSKNLFHVKEFPLEFENKLDFELAQQNGLLNSQPVCYPRVCKPSPIDDWMAVLSNNGNVSVFKDNKMLTNLDSKGNLSSRTYHCFEWNPIESSIVVGNEDGELQFFSIRKNSENTPEFYFESSIRLSDAGSKDWVTHIVWYEDVLVAALSNNSVFSMTVSASSHQPVSRMIQNASRRKITDLKIVDYKVVLTCPGYVHKIDLKNYSISSLKTGSLENFHIIPLNHEKESTILLMSNKTSYKVLLEDELHVTADNIIAPYLEKKFKKWSTIWNEFNNYETTLVIHGISLSPDGYSIAIVYDMERVAFKYKIASEQSFNIMFAPLYHTWTISERAVGLAWYQTYQIYNQSLPKLPENFSMNKKLLNGNYPISLDFQSYLNALMKSEEMRIIMFLNMTIDKPSILSFLEALYEYAINKKSELTNSFDLACVLSIAAILKREAPIYNGTLLMKNSFLEETFNLESFTADPETVTSTTNNTWKRCGVTLLPILTTHVKICPVSKQRVIDIKRDDLNDYGWFTRGLLERFNEISVYCGTTLEVM
SIO_010081: YPL007C
subclass of: SO_0000673
so part of: YPL007C
location: complement(542082..543848)
location: region:542082-543848:-1
so has part: feature:542082-543848:-1:exon

NP_015318.1
type: Protein
SIO_000068: ncbiprotein

S000005928
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:542082-543848:-1:exon

YPL006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NCR1
locus tag: YPL006W
so part of: sequence
location: <544631..>548143
location: region:544631-548143:1
so has part: feature:544631-548143:1:exon
subclass of: SO_0000010

856101
type: Gene
SIO_000068: ncbigene

position:544631:1
position: 544631
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:548143:1
position: 548143
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:544631-548143:1:exon

YPL006W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NCR1
locus tag: YPL006W
product: sphingolipid transporter
transcript id: NM_001183820.1
SIO_010081: YPL006W
subclass of: SO_0000673
so part of: YPL006W
location: <544631..>548143
location: region:544631-548143:1
so has part: feature:544631-548143:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:544631-548143:1:exon

YPL006W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NCR1
locus tag: YPL006W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:16138904|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0015918 sterol transport [PMID:31543266]
experiment: EXISTENCE:direct assay:GO:0032934 sterol binding [PMID:31543266]
experiment: EXISTENCE:mutant phenotype:GO:0006665 sphingolipid metabolic process [PMID:14970192]
note: Vacuolar membrane protein involved with Npc2p in sterol trafficking; transits through biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to accumulation of high amounts of lipids observed in patients with Neimann-Pick C disease caused by loss-of-function mutations in human NPC1; targeted to vacuole via AP-3 pathway
codon start: 1
product: sphingolipid transporter
translation: MNVLWIIALVGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPPVLSDETSKLLVEVCGEEWKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKVEKSKEDKDIVAELDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFLGDAKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYKCACSDCQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKNGAMIVDDDIVPESGSLDESETNVFESFNNETNFFNGKLANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVVNETGPVLSYETLHWWFDVENFITEELQSSENIGYQDLCFRPTEDSTCVIESFTQYFQGALPNKDSWKRELQECGKFPVNCLPTFQQPLKTNLLFSDDDILNAHAFVVTLLLTNHTQSANRWEERLEEYLLDLKVPEGLRISFNTEISLEKELNNNNDISTVAISYLMMFLYATWALRRKDGKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRNCEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSLYEKRSNYKQITGNEETKESFLKTFYFKMLTQKRLIIIIFSAWFFTSLVFLPEIQFGLDQTLAVPQDSYLVDYFKDVYSFLNVGPPVYMVVKNLDLTKRQNQQKICGKFTTCERDSLANVLEQERHRSTITEPLANWLDDYFMFLNPQNDQCCRLKKGTDEVCPPSFPSRRCETCFQQGSWNYNMSGFPEGKDFMEYLSIWINAPSDPCPLGGRAPYSTALVYNETSVSASVFRTAHHPLRSQKDFIQAYSDGVRISSSFPELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFLQNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGESYRDDSIEAED
SIO_010081: YPL006W
subclass of: SO_0000673
so part of: YPL006W
location: 544631..548143
location: region:544631-548143:1
so has part: feature:544631-548143:1:exon

NP_015319.1
type: Protein
SIO_000068: ncbiprotein

S000005927
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:544631-548143:1:exon

YPL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AEP3
locus tag: YPL005W
so part of: sequence
location: <548486..>550306
location: region:548486-550306:1
so has part: feature:548486-550306:1:exon
subclass of: SO_0000010

856102
type: Gene
SIO_000068: ncbigene

position:548486:1
position: 548486
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:550306:1
position: 550306
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:548486-550306:1:exon

YPL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AEP3
locus tag: YPL005W
product: Aep3p
transcript id: NM_001183819.1
SIO_010081: YPL005W
subclass of: SO_0000673
so part of: YPL005W
location: <548486..>550306
location: region:548486-550306:1
so has part: feature:548486-550306:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:548486-550306:1:exon

YPL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AEP3
locus tag: YPL005W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0070124 mitochondrial translational initiation [PMID:19843529]
experiment: EXISTENCE:mutant phenotype:GO:0016071 mRNA metabolic process [PMID:14742425]
note: Peripheral mitochondrial inner membrane protein; may facilitate use of unformylated tRNA-Met in mitochondrial translation initiation; stabilizes the bicistronic AAP1-ATP6 mRNA
codon start: 1
product: Aep3p
translation: MNTLRCLTQALSKSGREAPKLYQKVIFPGLFREGIPIANVKKVDEKIIDSPTSTSVNGEAKKIVRHGVKYEREQVKEYLSSLPTLTLSRKQIRDDYDEERAKRMYMFSKQTNSSNKFQKLLTAKSQEFTRELLTLLIDCTSNEKNSGPERFTRKFLKFSNDEIPPLPDFSKNPQLFENYIGILSHTKFNFRSSSKLNGIVRKMLRHLLHPTNKTTLPLRSAQVYNDSIYFFSEHFDFASCREIFAQMKAEGTKPNTITFNLLLRNVVKNSHIRKTKHPDDEVLFYLRSMRNHGVFADVITWTTCYNFLRDEVSRQLYIVQMGEHLGNFNVNFVYTVLRNGDYRAEDCLKVLAANSLPISRKTFYLCIERLLNEEQLETASKLLDYGFQHLKSNFKLDSEAMNHFMRVFANKGRSDLAFLCYNTCRKIYKIKPDSQTFEMLFKALVRNGNTKNFGAVLQYIKDLKVSEGFGLRTSYWRTKADSIFKFGSPNTLSEKSIEKARKLLGNLIASEGEFSWKIWKESDSSQKKILRFLGCIPTTLRCTNTAQDHQKPTNLPSNISQKKREYRNRVKAIATKAALEKRMAYIKDNDVAFKKELVKRRIVGEV
SIO_010081: YPL005W
subclass of: SO_0000673
so part of: YPL005W
location: 548486..550306
location: region:548486-550306:1
so has part: feature:548486-550306:1:exon

NP_015320.1
type: Protein
SIO_000068: ncbiprotein

S000005926
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:548486-550306:1:exon

YPL004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LSP1
locus tag: YPL004C
so part of: sequence
location: complement(<550632..>551657)
location: region:550632-551657:-1
so has part: feature:550632-551657:-1:exon
subclass of: SO_0000010

856103
type: Gene
SIO_000068: ncbigene

position:550632:-1
position: 550632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:551657:-1
position: 551657
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:550632-551657:-1:exon

YPL004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LSP1
locus tag: YPL004C
product: lipid-binding protein LSP1
transcript id: NM_001183818.1
SIO_010081: YPL004C
subclass of: SO_0000673
so part of: YPL004C
location: complement(<550632..>551657)
location: region:550632-551657:-1
so has part: feature:550632-551657:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:550632-551657:-1:exon

YPL004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LSP1
locus tag: YPL004C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:22123866]
experiment: EXISTENCE:direct assay:GO:0032126 eisosome [PMID:16496001]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006469 negative regulation of protein kinase activity [PMID:15016821]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:16496001]
experiment: EXISTENCE:mutant phenotype:GO:0009408 response to heat [PMID:15016821]
note: Eisosome core component; eisosomes are large immobile patch structures at the cell cortex associated with endocytosis; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; member of the BAR domain family
codon start: 1
product: lipid-binding protein LSP1
translation: MHRTYSLRNQRAPTAAELQAPPPPPSSTKSKFFGKASIASSFRKNAAGNFGPELARKLSQLVKTEKGVLRAMEVVASERREAAKQLSLWGADNDDDVSDVTDKLGVLIYELGELQDQFIDKYDQYRVTLKSIRNIEASVQPSRDRKEKITDEIAHLKYKDPQSTKIPVLEQELVRAEAESLVAEAQLSNITREKLKAAYSYMFDSLRELSEKFALIAGYGKALLELLDDSPVTPGEARPAYDGYEASRQIIMDAESALESWTLDMAAVKPTLSFHQTVDDVYEDEDGEEEEEPEIQNGDIPGQVVEEEEVEWTTEVPVDDEAHEADHHVSQNGHTSGSENI
SIO_010081: YPL004C
subclass of: SO_0000673
so part of: YPL004C
location: complement(550632..551657)
location: region:550632-551657:-1
so has part: feature:550632-551657:-1:exon

NP_015321.1
type: Protein
SIO_000068: ncbiprotein

S000005925
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:550632-551657:-1:exon

YPL003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ENR2
gene: ULA1
locus tag: YPL003W
gene synonym: ENR2
so part of: sequence
location: <552020..>553408
location: region:552020-553408:1
so has part: feature:552020-553408:1:exon
subclass of: SO_0000010

856104
type: Gene
SIO_000068: ncbigene

position:552020:1
position: 552020
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:553408:1
position: 553408
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:552020-553408:1:exon

YPL003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ENR2
gene: ULA1
locus tag: YPL003W
gene synonym: ENR2
product: Ula1p
transcript id: NM_001183817.1
SIO_010081: YPL003W
subclass of: SO_0000673
so part of: YPL003W
location: <552020..>553408
location: region:552020-553408:1
so has part: feature:552020-553408:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:552020-553408:1:exon

YPL003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ENR2
gene: ULA1
locus tag: YPL003W
gene synonym: ENR2
experiment: EXISTENCE:direct assay:GO:0019781 NEDD8 activating enzyme activity [PMID:9545234]
experiment: EXISTENCE:direct assay:GO:0045116 protein neddylation [PMID:9545234]
experiment: EXISTENCE:mutant phenotype:GO:0019781 NEDD8 activating enzyme activity [PMID:9531531]
experiment: EXISTENCE:mutant phenotype:GO:0045116 protein neddylation [PMID:9545234]
note: Protein that activates Rub1p (NEDD8) before neddylation; acts together with Uba3p; may play a role in protein degradation
codon start: 1
product: Ula1p
translation: MERYDRQLRLWGALGQDSLNRSRVCVVGPATPLLQEVFKNLVLAGISSLTWLKVECAVQSGSLFLAELKKDLEPLASKQLEYEENDLRKTLQQPQYDWTRFSVVILTCIGEQTAMLDLNEIRRQRGTKFPPVLNTFVSGFYGYIYLVLSETHFVLQAHPDSKKYDLRLQNPWPELINYVDTFDLSKMDTATFSGIPYTVLLMKCIAKLERDGNNGRITIDQMKKVLDQICLPLGNDVIYEPNYVEAKRYAYLACSQNDCCKELEDLLRNLEISDYGNDWHDTYNYEILTLLLTLKNIAKENGELSFQPLTGTLPDMESTTENYIRLKKLYEVKAKLDKSRVEESLARSKKIVSQDVLETFCSHYGEVRKILPPKSDLLGIFSTSNALLDALVMVQFWEQPAVTAEDKDEFIGLRVDDNYSVMAFFGGAVVQEAIKLITHHYVPIDNLFLYNGINNSSATYKI
SIO_010081: YPL003W
subclass of: SO_0000673
so part of: YPL003W
location: 552020..553408
location: region:552020-553408:1
so has part: feature:552020-553408:1:exon

NP_015322.1
type: Protein
SIO_000068: ncbiprotein

S000005924
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:552020-553408:1:exon

YPL002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: VPL14
alternative label: VPS22
gene: SNF8
locus tag: YPL002C
gene synonym: VPL14; VPS22
so part of: sequence
location: complement(<553627..>554328)
location: region:553627-554328:-1
so has part: feature:553627-554328:-1:exon
subclass of: SO_0000010

856105
type: Gene
SIO_000068: ncbigene

position:553627:-1
position: 553627
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:554328:-1
position: 554328
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:553627-554328:-1:exon

YPL002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: VPL14
alternative label: VPS22
gene: SNF8
locus tag: YPL002C
gene synonym: VPL14; VPS22
product: ESCRT-II subunit protein SNF8
transcript id: NM_001183816.1
SIO_010081: YPL002C
subclass of: SO_0000673
so part of: YPL002C
location: complement(<553627..>554328)
location: region:553627-554328:-1
so has part: feature:553627-554328:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:553627-554328:-1:exon

YPL002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: VPL14
alternative label: VPS22
gene: SNF8
locus tag: YPL002C
gene synonym: VPL14; VPS22
experiment: EXISTENCE:curator inference:GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:15086794]
experiment: EXISTENCE:direct assay:GO:0000814 ESCRT II complex [PMID:12194858]
experiment: EXISTENCE:mutant phenotype:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:7785322]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:12194858]
experiment: EXISTENCE:mutant phenotype:GO:1904669 ATP export [PMID:26585826]
note: Component of the ESCRT-II complex; ESCRT-II is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression
codon start: 1
product: ESCRT-II subunit protein SNF8
translation: MKQFGLAAFDELKDGKYNDVNKTILEKQSVELRDQLMVFQERLVEFAKKHNSELQASPEFRSKFMHMCSSIGIDPLSLFDRDKHLFTVNDFYYEVCLKVIEICRQTKDMNGGVISFQELEKVHFRKLNVGLDDLEKSIDMLKSLECFEIFQIRGKKFLRSVPNELTSDQTKILEICSILGYSSISLLKANLGWEAVRSKSALDEMVANGLLWIDYQGGAEALYWDPSWITRQL
SIO_010081: YPL002C
subclass of: SO_0000673
so part of: YPL002C
location: complement(553627..554328)
location: region:553627-554328:-1
so has part: feature:553627-554328:-1:exon

NP_015323.1
type: Protein
SIO_000068: ncbiprotein

S000005923
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:553627-554328:-1:exon

YPL001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KAT1
gene: HAT1
locus tag: YPL001W
gene synonym: KAT1
so part of: sequence
location: <554605..>555729
location: region:554605-555729:1
so has part: feature:554605-555729:1:exon
subclass of: SO_0000010

856106
type: Gene
SIO_000068: ncbigene

position:554605:1
position: 554605
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:555729:1
position: 555729
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:554605-555729:1:exon

YPL001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KAT1
gene: HAT1
locus tag: YPL001W
gene synonym: KAT1
product: histone acetyltransferase catalytic subunit HAT1
transcript id: NM_001183815.1
SIO_010081: YPL001W
subclass of: SO_0000673
so part of: YPL001W
location: <554605..>555729
location: region:554605-555729:1
so has part: feature:554605-555729:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:554605-555729:1:exon

YPL001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KAT1
gene: HAT1
locus tag: YPL001W
gene synonym: KAT1
EC number: 2.3.1.48
experiment: EXISTENCE:direct assay:GO:0000123 histone acetyltransferase complex [PMID:8858151|PMID:9575221]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:16612003]
experiment: EXISTENCE:direct assay:GO:0004402 histone acetyltransferase activity [PMID:7559580|PMID:8858151]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14761951|PMID:9575221]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8858151|PMID:9575221]
experiment: EXISTENCE:genetic interaction:GO:0031509 subtelomeric heterochromatin formation [PMID:10982821|PMID:15099519]
experiment: EXISTENCE:mutant phenotype:GO:0004402 histone acetyltransferase activity [PMID:7559580|PMID:8858151|PMID:9575221]
experiment: EXISTENCE:physical interaction:GO:0000123 histone acetyltransferase complex [PMID:8858151]
note: Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex; uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair
codon start: 1
product: histone acetyltransferase catalytic subunit HAT1
translation: MSANDFKPETWTSSANEALRVSIVGENAVQFSPLFTYPIYGDSEKIYGYKDLIIHLAFDSVTFKPYVNVKYSAKLGDDNIVDVEKKLLSFLPKDDVIVRDEAKWVDCFAEERKTHNLSDVFEKVSEYSLNGEEFVVYKSSLVDDFARRMHRRVQIFSLLFIEAANYIDETDPSWQIYWLLNKKTKELIGFVTTYKYWHYLGAKSFDEDIDKKFRAKISQFLIFPPYQNKGHGSCLYEAIIQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKSLKLEERQFNRLVEMLLLLNNSPSFELKVKNRLYIKNYDALDQTDPEKAREALQNSFILVKDDYRRIIESINKSQG
SIO_010081: YPL001W
subclass of: SO_0000673
so part of: YPL001W
location: 554605..555729
location: region:554605-555729:1
so has part: feature:554605-555729:1:exon

NP_015324.1
type: Protein
SIO_000068: ncbiprotein

S000005922
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:554605-555729:1:exon

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN16; Chromosome XVI centromere
so part of: sequence
location: 555957..556073
location: region:555957-556073:1
so has part: feature:555957-556073:1:region

S000006477
type: SGD
SIO_000068: sgd

position:555957:1
position: 555957
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:556073:1
position: 556073
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:555957-556073:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN16_CDEI of CEN16
so part of: sequence
location: 555957..555966
location: region:555957-555966:1
so has part: feature:555957-555966:1:region

position:555966:1
position: 555966
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:555957-555966:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN16_CDEII of CEN16
so part of: sequence
location: 555967..556048
location: region:555967-556048:1
so has part: feature:555967-556048:1:region

position:555967:1
position: 555967
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:556048:1
position: 556048
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:555967-556048:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN16_CDEIII of CEN16
so part of: sequence
location: 556049..556073
location: region:556049-556073:1
so has part: feature:556049-556073:1:region

position:556049:1
position: 556049
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:556049-556073:1:region

YPR001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CIT3
locus tag: YPR001W
so part of: sequence
location: <556377..>557837
location: region:556377-557837:1
so has part: feature:556377-557837:1:exon
subclass of: SO_0000010

856107
type: Gene
SIO_000068: ncbigene

position:556377:1
position: 556377
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:557837:1
position: 557837
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:556377-557837:1:exon

YPR001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CIT3
locus tag: YPR001W
product: citrate (Si)-synthase CIT3
transcript id: NM_001184098.1
SIO_010081: YPR001W
subclass of: SO_0000673
so part of: YPR001W
location: <556377..>557837
location: region:556377-557837:1
so has part: feature:556377-557837:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:556377-557837:1:exon

YPR001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CIT3
locus tag: YPR001W
EC number: 2.3.3.1
experiment: EXISTENCE:direct assay:GO:0004108 citrate (Si)-synthase activity [PMID:17570335]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:9140965|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0006099 tricarboxylic acid cycle [PMID:17570335]
experiment: EXISTENCE:direct assay:GO:0050440 2-methylcitrate synthase activity [PMID:17570335]
experiment: EXISTENCE:genetic interaction:GO:0019629 propionate catabolic process, 2-methylcitrate cycle [PMID:17570335]
experiment: EXISTENCE:mutant phenotype:GO:0004108 citrate (Si)-synthase activity [PMID:17570335]
experiment: EXISTENCE:mutant phenotype:GO:0050440 2-methylcitrate synthase activity [PMID:17570335]
note: Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate
codon start: 1
product: citrate (Si)-synthase CIT3
translation: MVQRLLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNKL
SIO_010081: YPR001W
subclass of: SO_0000673
so part of: YPR001W
location: 556377..557837
location: region:556377-557837:1
so has part: feature:556377-557837:1:exon

NP_015325.1
type: Protein
SIO_000068: ncbiprotein

S000006205
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:556377-557837:1:exon

YPR002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PDH1
locus tag: YPR002W
so part of: sequence
location: <558385..>559935
location: region:558385-559935:1
so has part: feature:558385-559935:1:exon
subclass of: SO_0000010

856108
type: Gene
SIO_000068: ncbigene

position:558385:1
position: 558385
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:559935:1
position: 559935
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:558385-559935:1:exon

YPR002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PDH1
locus tag: YPR002W
product: putative 2-methylcitrate dehydratase
transcript id: NM_001184099.1
SIO_010081: YPR002W
subclass of: SO_0000673
so part of: YPR002W
location: <558385..>559935
location: region:558385-559935:1
so has part: feature:558385-559935:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:558385-559935:1:exon

YPR002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PDH1
locus tag: YPR002W
EC number: 4.2.1.79
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:mutant phenotype:GO:0019541 propionate metabolic process [PMID:11179416]
note: Putative 2-methylcitrate dehydratase; mitochondrial protein that participates in respiration; induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate
codon start: 1
product: putative 2-methylcitrate dehydratase
translation: MFLAKNLKNNKIKVCLPKKKFAALSTASIQTNERPNPDKVLKDIAKYVHETPLKSSLALDTARLCFLDTLGCGLAALKFKQAQNIIKPIVPGTIVPSGTKILGTSYVMDPVKGAFAIGTLIRWLDYNDCWLAAEWGHPSDNLGGILAVADHLSRLNKATHGKNGKQFLVKDVLEAMIKAHEIQGIIALENSFNKVGLDHVVLVKVATAGVVSKMLGLSQEQTIEALSQAFVDGQSLRTYRHAPNTGSRKSWAAGDAVSRAVNLAYLVKNANVGTIPSVLTARTWGFYDVLFKGKPFSFQQRSKYDSYVMENVLFKISFPAEFHAQTAVEAAVKAYRILAKQGKTFKDIKSIRIRTQEAAMRIIDKSGPLYNYADRDHCIQYMIAVPLITGNLTATDYSDEVARNPEIDNLRSKMYCIEDTHLTQNYHDPDKRSIGNALLIELNDGTQLDEIFVEYPVGHKFRREEGIPLLMNKFQRHLREHFVESPDKVDLIMKVSSKTNFLNMQIDKYMDLFTEG
SIO_010081: YPR002W
subclass of: SO_0000673
so part of: YPR002W
location: 558385..559935
location: region:558385-559935:1
so has part: feature:558385-559935:1:exon

NP_015326.1
type: Protein
SIO_000068: ncbiprotein

S000006206
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:558385-559935:1:exon

YNCP0008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0008C
so part of: sequence
location: complement(560198..560289)
location: region:560198-560289:-1
so has part: feature:560198-560289:-1:exon
subclass of: SO_0000663

856109
type: Gene
SIO_000068: ncbigene

position:560198:-1
position: 560198
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:560289:-1
position: 560289
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:560198-560289:-1:exon

YNCP0008C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0008C
product: tRNA-Phe
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Phenylalanine tRNA (tRNA-Phe), predicted by tRNAscan-SE analysis
SIO_010081: YNCP0008C
subclass of: SO_0000673
so part of: YNCP0008C
location: complement(join(560198..560233,560253..560289))
location: region:560198-560289:-1
so has part: feature:560253-560289:-1:exon
so has part: feature:560198-560233:-1:exon

S000006570
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:560253-560289:-1:exon

position:560253:-1
position: 560253
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:560198-560233:-1:exon

position:560233:-1
position: 560233
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 560481..560812
location: region:560481-560812:1
so has part: feature:560481-560812:1:region

S000007210
type: SGD
SIO_000068: sgd

position:560481:1
position: 560481
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:560812:1
position: 560812
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:560481-560812:1:region

YPR003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR003C
so part of: sequence
location: complement(<561504..>563768)
location: region:561504-563768:-1
so has part: feature:561504-563768:-1:exon
subclass of: SO_0000010

856111
type: Gene
SIO_000068: ncbigene

position:561504:-1
position: 561504
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:563768:-1
position: 563768
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:561504-563768:-1:exon

YPR003C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR003C
product: uncharacterized protein
transcript id: NM_001184100.1
SIO_010081: YPR003C
subclass of: SO_0000673
so part of: YPR003C
location: complement(<561504..>563768)
location: region:561504-563768:-1
so has part: feature:561504-563768:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:561504-563768:-1:exon

YPR003C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR003C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
note: Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFNKLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESITLHKENVSLIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKDSIKYVIFDLGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV
SIO_010081: YPR003C
subclass of: SO_0000673
so part of: YPR003C
location: complement(561504..563768)
location: region:561504-563768:-1
so has part: feature:561504-563768:-1:exon

NP_015328.1
type: Protein
SIO_000068: ncbiprotein

S000006207
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:561504-563768:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1622; Autonomously Replicating Sequence
so part of: sequence
location: 563852..563967
location: region:563852-563967:1
so has part: feature:563852-563967:1:region

S000118418
type: SGD
SIO_000068: sgd

position:563852:1
position: 563852
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:563967:1
position: 563967
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:563852-563967:1:region

YPR004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM45
locus tag: YPR004C
so part of: sequence
location: complement(<564007..>565041)
location: region:564007-565041:-1
so has part: feature:564007-565041:-1:exon
subclass of: SO_0000010

856112
type: Gene
SIO_000068: ncbigene

position:564007:-1
position: 564007
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:565041:-1
position: 565041
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:564007-565041:-1:exon

YPR004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM45
locus tag: YPR004C
product: Aim45p
transcript id: NM_001184101.1
SIO_010081: YPR004C
subclass of: SO_0000673
so part of: YPR004C
location: complement(<564007..>565041)
location: region:564007-565041:-1
so has part: feature:564007-565041:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:564007-565041:-1:exon

YPR004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM45
locus tag: YPR004C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:17054397|PMID:14562095|PMID:14576278|P MID:16823961|PMID:24769239]
note: Putative ortholog of mammalian ETF-alpha; interacts with frataxin, Yfh1p; null mutant displays elevated frequency of mitochondrial genome loss; may have a role in oxidative stress response; ETF-alpha is an electron transfer flavoprotein complex subunit
codon start: 1
product: Aim45p
translation: MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLLAAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLVKLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIISTIECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELTSAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVAPNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKLGKYK
SIO_010081: YPR004C
subclass of: SO_0000673
so part of: YPR004C
location: complement(564007..565041)
location: region:564007-565041:-1
so has part: feature:564007-565041:-1:exon

NP_015329.1
type: Protein
SIO_000068: ncbiprotein

S000006208
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:564007-565041:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1634; Autonomously Replicating Sequence
so part of: sequence
location: 565052..565294
location: region:565052-565294:1
so has part: feature:565052-565294:1:region

S000119040
type: SGD
SIO_000068: sgd

position:565052:1
position: 565052
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:565294:1
position: 565294
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:565052-565294:1:region

YPR005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HAL1
locus tag: YPR005C
so part of: sequence
location: complement(<565787..>566671)
location: region:565787-566671:-1
so has part: feature:565787-566671:-1:exon
subclass of: SO_0000010

856113
type: Gene
SIO_000068: ncbigene

position:565787:-1
position: 565787
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:566671:-1
position: 566671
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:565787-566671:-1:exon

YPR005C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HAL1
locus tag: YPR005C
product: Hal1p
transcript id: NM_001184102.1
SIO_010081: YPR005C
subclass of: SO_0000673
so part of: YPR005C
location: complement(<565787..>566671)
location: region:565787-566671:-1
so has part: feature:565787-566671:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:565787-566671:-1:exon

YPR005C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HAL1
locus tag: YPR005C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:1505513]
experiment: EXISTENCE:mutant phenotype:GO:0009651 response to salt stress [PMID:1505513]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:1505513]
note: Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p
codon start: 1
product: Hal1p
translation: MHFKDLGLHDYTLKNLMYENNCCKFYDAVDENNISYVLKFVPSDVTSEGDTFPFVDRFQVKEGVFLVYSSNDFGKEGTDYFTYTGSGGNEVHISGTSSEAGIKPQFIETCHPKHLKRGTKEQEDINSSTSKKSAVINNFSGEKTPNPRPQSSNISERETYVGILNVKCKNKNSSKIRSEKLVSSVIETKHTPGLASILSKEGTTYPNNADGKHISIVNPSSKIYHSSHKQIVKTPIPKSGLSPIERCPFNGQNIKCYSPRPLDHESPQRDFNNNFQLRILKSSVLQRRQSTQNS
SIO_010081: YPR005C
subclass of: SO_0000673
so part of: YPR005C
location: complement(565787..566671)
location: region:565787-566671:-1
so has part: feature:565787-566671:-1:exon

NP_015330.1
type: Protein
SIO_000068: ncbiprotein

S000006209
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:565787-566671:-1:exon

YPR006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ICL2
locus tag: YPR006C
so part of: sequence
location: complement(<567269..>568996)
location: region:567269-568996:-1
so has part: feature:567269-568996:-1:exon
subclass of: SO_0000010

856114
type: Gene
SIO_000068: ncbigene

position:567269:-1
position: 567269
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:568996:-1
position: 568996
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:567269-568996:-1:exon

YPR006C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ICL2
locus tag: YPR006C
product: methylisocitrate lyase ICL2
transcript id: NM_001184103.1
SIO_010081: YPR006C
subclass of: SO_0000673
so part of: YPR006C
location: complement(<567269..>568996)
location: region:567269-568996:-1
so has part: feature:567269-568996:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:567269-568996:-1:exon

YPR006C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ICL2
locus tag: YPR006C
EC number: 4.1.3.30
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:11092862]
experiment: EXISTENCE:direct assay:GO:0019629 propionate catabolic process, 2-methylcitrate cycle [PMID:11092862]
experiment: EXISTENCE:direct assay:GO:0046421 methylisocitrate lyase activity [PMID:11092862]
note: 2-methylisocitrate lyase of the mitochondrial matrix; functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol
codon start: 1
product: methylisocitrate lyase ICL2
translation: MITMINNKTFNRKTTGTLKKLVLSSDKSLRRSFNGASSTKDFVFSESSKVEEWWESARFKNISRPYSATDVVKHRGSLPANTSIYPSSYQARKLFNLLEENFKNGTPLHTLGVIDPVQMSQLARCRNIKVAYISGWACSSTLVGSTNEVSPDFGDYPYDTVPNQVERIFKAQQLHDRKAFLEASIKGSTPVDYLKPIIADADMGHGGPTTVMKVAKLFAEKGAAGIHLEDQMVGGKRCGHLSGAVLVPTATHLMRLISTRFQWDIMGTENLVIARTDSCNGKLLSSSSDPRDHEFIRGIIRDNVVPWSEKLIEMEDKKIPNSAIADMEKEWYHENELFTFEEALEKQFTASEFESYKEKKEDLMVNKLGRAYLSLREMKLLAQEVTPLKKIIFDWDAPRTKEGYYMFNGCIEAAIRRSLVFAPYSDMIWLETKTPDLEQARSFSRKIHKQLPATKLVYNLSPSFNWSAHGFDDKALKSFVWDLAKEGFTLQLVSLAGLHSDGVSFWELANSFQSDGMKAYVEKVQKREKETNCDIMTHQLWSGAEYVDSLMKVVQNGASSQTLSTSGESFTETQF
SIO_010081: YPR006C
subclass of: SO_0000673
so part of: YPR006C
location: complement(567269..568996)
location: region:567269-568996:-1
so has part: feature:567269-568996:-1:exon

NP_015331.1
type: Protein
SIO_000068: ncbiprotein

S000006210
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:567269-568996:-1:exon

YPR007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SPO69
gene: REC8
locus tag: YPR007C
gene synonym: SPO69
so part of: sequence
location: complement(<569336..>571378)
location: region:569336-571378:-1
so has part: feature:569336-571378:-1:exon
subclass of: SO_0000010

856115
type: Gene
SIO_000068: ncbigene

position:569336:-1
position: 569336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:571378:-1
position: 571378
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:569336-571378:-1:exon

YPR007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SPO69
gene: REC8
locus tag: YPR007C
gene synonym: SPO69
product: Rec8p
transcript id: NM_001184104.1
SIO_010081: YPR007C
subclass of: SO_0000673
so part of: YPR007C
location: complement(<569336..>571378)
location: region:569336-571378:-1
so has part: feature:569336-571378:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:569336-571378:-1:exon

YPR007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SPO69
gene: REC8
locus tag: YPR007C
gene synonym: SPO69
experiment: EXISTENCE:direct assay:GO:0000779 condensed chromosome, centromeric region [PMID:10412984|PMID:16357219]
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:16357219]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:23246437]
experiment: EXISTENCE:genetic interaction:GO:0071459 protein localization to chromosome, centromeric region [PMID:16357219]
experiment: EXISTENCE:mutant phenotype:GO:0007130 synaptonemal complex assembly [PMID:10412984]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:10412984]
experiment: EXISTENCE:mutant phenotype:GO:0042138 meiotic DNA double-strand break formation [PMID:31617566]
experiment: EXISTENCE:mutant phenotype:GO:0051177 meiotic sister chromatid cohesion [PMID:10412984]
note: Meiosis-specific component of the sister chromatid cohesion complex; alpha-kleisin family member that maintains cohesion between homologous chromosomes during meiosis I until chromosome arm-associated Rec8p is cleaved by Esp1p; cohesion between sister chromatid centromeres is maintained until metaphase of meiosis II when it is cleaved by Esp1; independent of the role in cohesion, Rec8p promotes allelic collisions and prevents nonspecific chromosome interactions; homolog of S. pombe Rec8p
codon start: 1
product: Rec8p
translation: MAPLSLNFKDDKKYKGLTTVWLLSALGNSIVKESNNYYSNKSNSTGNISSSTVKKKDIVNISIPKTCDEIQNFENDFSLRYISNLLYGVTICYNKKTEYVLNDLNHLLVQLQKNDVYAFKAKNKSTRINGLNSNNSIIGNKNNNYTWEECVFFDDDPLYDITKVPALEFLNTTLQDNVSFIEEAKSIRRQDYINELSNSNRFELHGDMTNSDAQSNLGSNVRNSFPLDEIPVDVDFNLDLDDIVSHQGTPLGSHSSSQKDGNDFKFNYQGDELVLNFENDNENNSNGGEDTSVENEGPVANLKDYELGLEAQASEEENDLQQKLNTRMQRGHRADVGGQFSKVQFDAKTSYPNEVLKFNHGNYSHLMEKNRIRKLTGQNFLTSNISSLVRSCGEEEFFSTNWLSIFNDFSNIKTSEWDLYPQGFSSVERGRKRAHSLVSTQSSSSTRSHEYGRKSFRNNKNDNYSSDMENDNLLLNLEQINEDLEDGHYIEENSQGNILDFNLNLPPSSFGRSHTRNSTRSSGFNEDIVGALRRRVGPSEQNFAEEDDSSNSCFSDGSQQNLQQDKTNFQDVILDYQTKKFYDYIKERSIVVGRTTRSNPPFKRKMLLVDIIPSRMGEAQTGANFDDVERGVSRQIAASAFLSLLNLATKGMVKLNEYPVADAVTKDLKLRREDEIIVYA
SIO_010081: YPR007C
subclass of: SO_0000673
so part of: YPR007C
location: complement(569336..571378)
location: region:569336-571378:-1
so has part: feature:569336-571378:-1:exon

NP_015332.1
type: Protein
SIO_000068: ncbiprotein

S000006211
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:569336-571378:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(571845..572173)
location: region:571845-572173:-1
so has part: feature:571845-572173:-1:region

S000007200
type: SGD
SIO_000068: sgd

position:571845:-1
position: 571845
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:572173:-1
position: 572173
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:571845-572173:-1:region

YNCP0009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0009W
so part of: sequence
location: 572269..572339
location: region:572269-572339:1
so has part: feature:572269-572339:1:exon
subclass of: SO_0000663

856116
type: Gene
SIO_000068: ncbigene

position:572269:1
position: 572269
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:572339:1
position: 572339
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:572269-572339:1:exon

YNCP0009W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0009W
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis
SIO_010081: YNCP0009W
subclass of: SO_0000673
so part of: YNCP0009W
location: 572269..572339
location: region:572269-572339:1
so has part: feature:572269-572339:1:exon

S000006588
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:572269-572339:1:exon

YPR008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HAA1
locus tag: YPR008W
so part of: sequence
location: <573018..>575102
location: region:573018-575102:1
so has part: feature:573018-575102:1:exon
subclass of: SO_0000010

856117
type: Gene
SIO_000068: ncbigene

position:573018:1
position: 573018
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:575102:1
position: 575102
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:573018-575102:1:exon

YPR008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HAA1
locus tag: YPR008W
product: Haa1p
transcript id: NM_001184105.1
SIO_010081: YPR008W
subclass of: SO_0000673
so part of: YPR008W
location: <573018..>575102
location: region:573018-575102:1
so has part: feature:573018-575102:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:573018-575102:1:exon

YPR008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HAA1
locus tag: YPR008W
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:21586585]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11504737]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11504737]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11504737|PMID:16176797|PMID:16980434|PMID:28068993]
note: Transcriptional activator involved in adaptation to weak acid stress; activates transcription of TPO2, YRO2, and other genes encoding membrane stress proteins; HAA1 has a paralog, CUP2, that arose from the whole genome duplication; relocalizes from cytoplasm to nucleus upon DNA replication stress
codon start: 1
product: Haa1p
translation: MVLINGIKYACERCIRGHRVTTCNHTDQPLMMIKPKGRPSTTCDYCKQLRKNKNANPEGVCTCGRLEKKKLAQKAKEEARAKAKEKQRKQCTCGTDEVCKYHAQKRHLRKSPSSSQKKGRSISRSQPMFERVLSSTSLDSNMLSGHGALSDTSSILTSTFLDSEPGVGKISKDYHHVPSLASISSLQSSQSLDQNFSIPQSPPLSSMSFNFLTGNINETNQNHSNHQHSKSGNNWQDSSVSLPAKADSRLNMMDKNNSVGLDLLGHSKRISPISNSRVGEVSVPLEEYIPSDIDGVGRVTDKSSLVYDWPFDESIERNFSTTATAATGESKFDINDNCNRINSKSYSKTNSMNGNGMNNSNNNNINSNGNDKNNNNSSRQEHQGNGLFDMFTDSSSISTLSRANLLLQEKIGSQENSVKQENYSKNPQLRHQLTSRSRSFIHHPANEYLKNTFGNSHSNDIGKGVEVLSLTPSFMDIPEKERETERSPSSNYITDRPFTRKPRSSSIDVNHRYPPMAPTTVATSPGALNNAVASNLDDQLSLTSLNSQPSSIANMMMDPSNLAEQSSIHSVPQSINSPRMPKTGSRQDKNIHTKKEERNPLNNIHDLSQLENVPDEMNQMFSPPLKSMNRPDAIRENSSSSNFIIQGNSMISTPSGRNDLPDTSPMSSIQTASPPSQLLTDQGFADLDNFMSSL
SIO_010081: YPR008W
subclass of: SO_0000673
so part of: YPR008W
location: 573018..575102
location: region:573018-575102:1
so has part: feature:573018-575102:1:exon

NP_015333.1
type: Protein
SIO_000068: ncbiprotein

S000006212
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:573018-575102:1:exon

YPR009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUT2
locus tag: YPR009W
so part of: sequence
location: <576552..>577358
location: region:576552-577358:1
so has part: feature:576552-577358:1:exon
subclass of: SO_0000010

856118
type: Gene
SIO_000068: ncbigene

position:576552:1
position: 576552
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:577358:1
position: 577358
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:576552-577358:1:exon

YPR009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SUT2
locus tag: YPR009W
product: Sut2p
transcript id: NM_001184106.1
SIO_010081: YPR009W
subclass of: SO_0000673
so part of: YPR009W
location: <576552..>577358
location: region:576552-577358:1
so has part: feature:576552-577358:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:576552-577358:1:exon

YPR009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SUT2
locus tag: YPR009W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15030478]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:genetic interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:23872066]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:26448198|PMID:23872066]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11248676]
note: Zn2Cys6 family transcription factor; positively regulates sterol uptake under anaerobic conditions with SUT1; represses filamentation-inducing genes during non-starvation conditions; positively regulates mating along with SUT1 by repressing the expression of genes (PRR2, NCE102 and RHO5) which function as mating inhibitors; multicopy suppressor of mutations that cause low activity of the cAMP/PKA pathway; SUT2 has a paralog, SUT1, that arose from the whole genome duplication
codon start: 1
product: Sut2p
translation: MKPNNRTCDVITNKDESLPALLLPALNSYTCDDSLLKGQISSNGRYQPFGFSDCSLLPKRLNIQAGQGSMPVSSIQCADHSYSNWQKESEKTKLPKLGCPTEYTEYYKTVSSGETTDSAVVSSIATNRLKRKRQRDGPSCDSCRIKKIKCNATIIIFLQDRNLISSISSNLHYTLSQDDINQFRMKFFRKLPDVMGTYEVIKHLDKIVLFKACTSCSRRNQKNGKCLFSRGFTKSDMNVFPKINSKLKDKSIFEMTVDDYVAAGFQTL
SIO_010081: YPR009W
subclass of: SO_0000673
so part of: YPR009W
location: 576552..577358
location: region:576552-577358:1
so has part: feature:576552-577358:1:exon

NP_015334.1
type: Protein
SIO_000068: ncbiprotein

S000006213
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:576552-577358:1:exon

YPR010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPA2
alternative label: RRN2
alternative label: SRP3
gene: RPA135
locus tag: YPR010C
gene synonym: RPA2; RRN2; SRP3
so part of: sequence
location: complement(<577585..>581196)
location: region:577585-581196:-1
so has part: feature:577585-581196:-1:exon
subclass of: SO_0000010

856119
type: Gene
SIO_000068: ncbigene

position:577585:-1
position: 577585
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:581196:-1
position: 581196
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:577585-581196:-1:exon

YPR010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPA2
alternative label: RRN2
alternative label: SRP3
gene: RPA135
locus tag: YPR010C
gene synonym: RPA2; RRN2; SRP3
product: DNA-directed RNA polymerase I core subunit RPA135
transcript id: NM_001184107.1
SIO_010081: YPR010C
subclass of: SO_0000673
so part of: YPR010C
location: complement(<577585..>581196)
location: region:577585-581196:-1
so has part: feature:577585-581196:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:577585-581196:-1:exon

YPR010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPA2
alternative label: RRN2
alternative label: SRP3
gene: RPA135
locus tag: YPR010C
gene synonym: RPA2; RRN2; SRP3
EC number: 2.7.7.6
experiment: EXISTENCE:direct assay:GO:0001054 RNA polymerase I activity [PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0005736 RNA polymerase I complex [PMID:11486042|PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0006360 transcription by RNA polymerase I [PMID:9837969]
experiment: EXISTENCE:genetic interaction:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:2023944]
note: RNA polymerase I second largest subunit A135
codon start: 1
product: DNA-directed RNA polymerase I core subunit RPA135
translation: MSKVIKPPGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEDEISNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLLTKSEDGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK
SIO_010081: YPR010C
subclass of: SO_0000673
so part of: YPR010C
location: complement(577585..581196)
location: region:577585-581196:-1
so has part: feature:577585-581196:-1:exon

NP_015335.1
type: Protein
SIO_000068: ncbiprotein

S000006214
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:577585-581196:-1:exon

YNCP0010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0010W
so part of: sequence
location: 582062..582134
location: region:582062-582134:1
so has part: feature:582062-582134:1:exon
subclass of: SO_0000663

856120
type: Gene
SIO_000068: ncbigene

position:582062:1
position: 582062
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:582134:1
position: 582134
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:582062-582134:1:exon

YNCP0010W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0010W
product: tRNA-Lys
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8915539]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8915539]
experiment: EXISTENCE:mutant phenotype:GO:0030533 triplet codon-amino acid adaptor activity [PMID:17560369]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:17560369]
note: Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced
SIO_010081: YNCP0010W
subclass of: SO_0000673
so part of: YNCP0010W
location: 582062..582134
location: region:582062-582134:1
so has part: feature:582062-582134:1:exon

S000006628
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:582062-582134:1:exon

YPR010C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIN8
locus tag: YPR010C-A
so part of: sequence
location: complement(<582373..>582734)
location: region:582373-582734:-1
so has part: feature:582373-582734:-1:exon
subclass of: SO_0000010

5142379
type: Gene
SIO_000068: ncbigene

position:582373:-1
position: 582373
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:582734:-1
position: 582734
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:582373-582734:-1:exon

YPR010C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIN8
locus tag: YPR010C-A
product: Min8p
transcript id: NM_001184689.1
SIO_010081: YPR010C-A
subclass of: SO_0000673
so part of: YPR010C-A
location: complement(join(<582373..582558,582702..>582734))
location: region:582373-582734:-1
so has part: feature:582702-582734:-1:exon
so has part: feature:582373-582558:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:582702-582734:-1:exon

position:582702:-1
position: 582702
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:582373-582558:-1:exon

position:582558:-1
position: 582558
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPR010C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIN8
locus tag: YPR010C-A
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
note: hypothetical protein; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to cytosol; conserved among Saccharomyces sensu stricto species
codon start: 1
product: Min8p
translation: MRPAQLLLNTAKKTSGGYKIPVELTPLFLAVGVALCSGTYFTYKKLRTDETLRLTGNPELSSLDEVLAKDKD
SIO_010081: YPR010C-A
subclass of: SO_0000673
so part of: YPR010C-A
location: complement(join(582373..582558,582702..582734))
location: region:582373-582734:-1
so has part: feature:582702-582734:-1:exon
so has part: feature:582373-582558:-1:exon

NP_001091638.1
type: Protein
SIO_000068: ncbiprotein

S000122558
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:582702-582734:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:582373-582558:-1:exon

YPR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX21
locus tag: YPR011C
so part of: sequence
location: complement(<583062..>584042)
location: region:583062-584042:-1
so has part: feature:583062-584042:-1:exon
subclass of: SO_0000010

856121
type: Gene
SIO_000068: ncbigene

position:583062:-1
position: 583062
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:584042:-1
position: 584042
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:583062-584042:-1:exon

YPR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX21
locus tag: YPR011C
product: Mrx21p
transcript id: NM_001184108.1
SIO_010081: YPR011C
subclass of: SO_0000673
so part of: YPR011C
location: complement(<583062..>584042)
location: region:583062-584042:-1
so has part: feature:583062-584042:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:583062-584042:-1:exon

YPR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX21
locus tag: YPR011C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity [PMID:24296033]
experiment: EXISTENCE:direct assay:GO:1902557 5'-adenylyl sulfate transmembrane transporter activity [PMID:24296033]
experiment: EXISTENCE:direct assay:GO:1902558 5'-adenylyl sulfate transmembrane transport [PMID:24296033]
experiment: EXISTENCE:direct assay:GO:1902559 3'-phospho-5'-adenylyl sulfate transmembrane transport [PMID:24296033]
note: Mitochondrial transporter; major substrates are adenosine 5'-phosphosulfate (APS) and 3'-phospho-adenosine 5'-phosphosulfate (PAPS); member of the mitochondrial carrier family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Mrx21p
translation: MAEVLTVLEQPNSIKDFLKQDSNIAFLAGGVAGAVSRTVVSPFERVKILLQVQSSTTSYNRGIFSSIRQVYHEEGTKGLFRGNGLNCIRIFPYSAVQFVVYEACKKKLFHVNGNNGQEQLTNTQRLFSGALCGGCSVVATYPLDLIKTRLSIQTANLSSLNRSKAKSISKPPGIWQLLSETYRLEGGLRGLYRGVWPTSLGVVPYVALNFAVYEQLREFGVNSSDAQPSWKSNLYKLTIGAISGGVAQTITYPFDLLRRRFQVLAMGGNELGFRYTSVWDALVTIGRAEGVSGYYKGLAANLFKVVPSTAVSWLVYEVVCDSVRNW
SIO_010081: YPR011C
subclass of: SO_0000673
so part of: YPR011C
location: complement(583062..584042)
location: region:583062-584042:-1
so has part: feature:583062-584042:-1:exon

NP_015336.1
type: Protein
SIO_000068: ncbiprotein

S000006215
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:583062-584042:-1:exon

YPR013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CMR3
locus tag: YPR013C
so part of: sequence
location: complement(<584632..>585585)
location: region:584632-585585:-1
so has part: feature:584632-585585:-1:exon
subclass of: SO_0000010

856123
type: Gene
SIO_000068: ncbigene

position:584632:-1
position: 584632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:585585:-1
position: 585585
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:584632-585585:-1:exon

YPR013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CMR3
locus tag: YPR013C
product: Cmr3p
transcript id: NM_001184110.1
SIO_010081: YPR013C
subclass of: SO_0000673
so part of: YPR013C
location: complement(<584632..>585585)
location: region:584632-585585:-1
so has part: feature:584632-585585:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:584632-585585:-1:exon

YPR013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CMR3
locus tag: YPR013C
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:23012409]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
note: Putative zinc finger protein; YPR013C is not an essential gene
codon start: 1
product: Cmr3p
translation: MNFSLSKQSSEKQSSYTDKSRSPNIGMCTVNYKSNLPLQVSAVDQLSTGKGTQFYGHNSYKNERECYNSTKINLPPISSLLPNFENNTPPNVDSRVQFPPQQVYQSMNVVPIVNEIYTPISMNATSDQYPIYYTESQQPIPHSQSPHLTSSAPLMMPVMVPTVYKPLTPYDKEPITIASEPNFTAISMASHPNAALELCHDRPKSVPPGYGVLPTMQEASNGRTKSEPGAVLNGSATFSDWKTDTRISSTKLRKQCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKRNKVLNTT
SIO_010081: YPR013C
subclass of: SO_0000673
so part of: YPR013C
location: complement(584632..585585)
location: region:584632-585585:-1
so has part: feature:584632-585585:-1:exon

NP_015338.1
type: Protein
SIO_000068: ncbiprotein

S000006217
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:584632-585585:-1:exon

YPR014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR014C
so part of: sequence
location: complement(<587189..>587518)
location: region:587189-587518:-1
so has part: feature:587189-587518:-1:exon
subclass of: SO_0000010

856124
type: Gene
SIO_000068: ncbigene

position:587189:-1
position: 587189
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:587518:-1
position: 587518
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:587189-587518:-1:exon

YPR014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR014C
product: uncharacterized protein
transcript id: NM_001348886.1
SIO_010081: YPR014C
subclass of: SO_0000673
so part of: YPR014C
location: complement(<587189..>587518)
location: region:587189-587518:-1
so has part: feature:587189-587518:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:587189-587518:-1:exon

YPR014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR014C
note: hypothetical protein; conserved across S. cerevisiae strains; YPR014C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MSCIFSADLGVEYSCAESRITNLVLCILCIREEKAAPVVKKDKFLFFIFLSSKENLFCEISSRSSVSEVKSLRAKNNFICPHAVIGFQGAKAQLGIRFPQLNGLLRLQH
SIO_010081: YPR014C
subclass of: SO_0000673
so part of: YPR014C
location: complement(587189..587518)
location: region:587189-587518:-1
so has part: feature:587189-587518:-1:exon

NP_001335824.1
type: Protein
SIO_000068: ncbiprotein

S000006218
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:587189-587518:-1:exon

YPR015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR015C
so part of: sequence
location: complement(<590283..>591026)
location: region:590283-591026:-1
so has part: feature:590283-591026:-1:exon
subclass of: SO_0000010

856125
type: Gene
SIO_000068: ncbigene

position:590283:-1
position: 590283
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:591026:-1
position: 591026
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:590283-591026:-1:exon

YPR015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR015C
product: uncharacterized protein
transcript id: NM_001184112.1
SIO_010081: YPR015C
subclass of: SO_0000673
so part of: YPR015C
location: complement(<590283..>591026)
location: region:590283-591026:-1
so has part: feature:590283-591026:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:590283-591026:-1:exon

YPR015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR015C
experiment: EXISTENCE:mutant phenotype:GO:0000077 DNA damage checkpoint signaling [PMID:18617996]
note: Putative zinc finger transcription factor; binds DNA in sequence-specific manner; overexpression causes a cell cycle delay or arrest
codon start: 1
product: uncharacterized protein
translation: MWRTKTLESMLCSPMKCSSSNIGGSYAQSSKEVSNTTKREVHLPPCSSIMHAPLTPEINQAALPPPAYHYAPSSLHQTEDPVWRSSPNSIIFSPVIATPQPFPLTFVERQSCCPIYSTAASSYTAQSVPPSMQHFQEENHRAVSNEQYSLPNVHIGQNPGTLLSQTQTDLDLIQKQLRAVVKLRKQCPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHLRTHQKKIAKKKHQ
SIO_010081: YPR015C
subclass of: SO_0000673
so part of: YPR015C
location: complement(590283..591026)
location: region:590283-591026:-1
so has part: feature:590283-591026:-1:exon

NP_015340.1
type: Protein
SIO_000068: ncbiprotein

S000006219
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:590283-591026:-1:exon

YPR016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC95
gene: TIF6
locus tag: YPR016C
gene synonym: CDC95
so part of: sequence
location: complement(<592332..>593069)
location: region:592332-593069:-1
so has part: feature:592332-593069:-1:exon
subclass of: SO_0000010

856126
type: Gene
SIO_000068: ncbigene

position:592332:-1
position: 592332
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:593069:-1
position: 593069
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:592332-593069:-1:exon

YPR016C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC95
gene: TIF6
locus tag: YPR016C
gene synonym: CDC95
product: translation initiation factor 6
transcript id: NM_001184113.1
SIO_010081: YPR016C
subclass of: SO_0000673
so part of: YPR016C
location: complement(<592332..>593069)
location: region:592332-593069:-1
so has part: feature:592332-593069:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:592332-593069:-1:exon

YPR016C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC95
gene: TIF6
locus tag: YPR016C
gene synonym: CDC95
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11238882]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:17353896]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11238882]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614|PMID:16188229|PMID:17443350|PMID:23212245]
experiment: EXISTENCE:direct assay:GO:0043023 ribosomal large subunit binding [PMID:9891075]
experiment: EXISTENCE:genetic interaction:GO:0000054 ribosomal subunit export from nucleus [PMID:17353896]
experiment: EXISTENCE:genetic interaction:GO:0006364 rRNA processing [PMID:17353896]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11238882]
experiment: EXISTENCE:mutant phenotype:GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11238882]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:10206977|PMID:11238882]
experiment: EXISTENCE:mutant phenotype:GO:1902626 assembly of large subunit precursor of preribosome [PMID:22735702]
note: Constituent of 66S pre-ribosomal particles; has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits
codon start: 1
product: translation initiation factor 6
translation: MATRTQFENSNEIGVFSKLTNTYCLVAVGGSENFYSAFEAELGDAIPIVHTTIAGTRIIGRMTAGNRRGLLVPTQTTDQELQHLRNSLPDSVKIQRVEERLSALGNVICCNDYVALVHPDIDRETEELISDVLGVEVFRQTISGNILVGSYCSLSNQGGLVHPQTSVQDQEELSSLLQVPLVAGTVNRGSSVVGAGMVVNDYLAVTGLDTTAPELSVIESIFRLQDAQPESISGNLRDTLIETYS
SIO_010081: YPR016C
subclass of: SO_0000673
so part of: YPR016C
location: complement(592332..593069)
location: region:592332-593069:-1
so has part: feature:592332-593069:-1:exon

NP_015341.1
type: Protein
SIO_000068: ncbiprotein

S000006220
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:592332-593069:-1:exon

YPR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DSS4
locus tag: YPR017C
so part of: sequence
location: complement(<593486..>593917)
location: region:593486-593917:-1
so has part: feature:593486-593917:-1:exon
subclass of: SO_0000010

856128
type: Gene
SIO_000068: ncbigene

position:593486:-1
position: 593486
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:593917:-1
position: 593917
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:593486-593917:-1:exon

YPR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DSS4
locus tag: YPR017C
product: guanine nucleotide exchange factor DSS4
transcript id: NM_001184114.1
SIO_010081: YPR017C
subclass of: SO_0000673
so part of: YPR017C
location: complement(<593486..>593917)
location: region:593486-593917:-1
so has part: feature:593486-593917:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:593486-593917:-1:exon

YPR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DSS4
locus tag: YPR017C
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:9218467]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:9218467|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008270 zinc ion binding [PMID:9218467]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:9218467]
experiment: EXISTENCE:genetic interaction:GO:0006892 post-Golgi vesicle-mediated transport [PMID:8429886|PMID:9218467]
experiment: EXISTENCE:mutant phenotype:GO:0006892 post-Golgi vesicle-mediated transport [PMID:8429886|PMID:9218467]
experiment: EXISTENCE:physical interaction:GO:0006892 post-Golgi vesicle-mediated transport [PMID:9218467]
note: Guanine nucleotide dissociation stimulator for Sec4p; functions in the post-Golgi secretory pathway; binds zinc, found both on membranes and in the cytosol
codon start: 1
product: guanine nucleotide exchange factor DSS4
translation: MSKATCSFEGCHSAVITINDDNIINLPEQVHSEFKLLENRTMRDATPSESNFLVVPDVWDFDNVGVSREIPSSILGDLSDKSDFVFEYGNSSWKIKKCLKYLICADCDKGPIGIICKVQDQTKNEERVLHLLSLRSLQIMGRN
SIO_010081: YPR017C
subclass of: SO_0000673
so part of: YPR017C
location: complement(593486..593917)
location: region:593486-593917:-1
so has part: feature:593486-593917:-1:exon

NP_015342.1
type: Protein
SIO_000068: ncbiprotein

S000006221
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:593486-593917:-1:exon

YPR018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CAC1
gene: RLF2
locus tag: YPR018W
gene synonym: CAC1
so part of: sequence
location: <594476..>596296
location: region:594476-596296:1
so has part: feature:594476-596296:1:exon
subclass of: SO_0000010

856129
type: Gene
SIO_000068: ncbigene

position:594476:1
position: 594476
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:596296:1
position: 596296
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:594476-596296:1:exon

YPR018W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CAC1
gene: RLF2
locus tag: YPR018W
gene synonym: CAC1
product: Rlf2p
transcript id: NM_001184115.1
SIO_010081: YPR018W
subclass of: SO_0000673
so part of: YPR018W
location: <594476..>596296
location: region:594476-596296:1
so has part: feature:594476-596296:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:594476-596296:1:exon

YPR018W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CAC1
gene: RLF2
locus tag: YPR018W
gene synonym: CAC1
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:11782447]
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:25602519]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9030688]
experiment: EXISTENCE:direct assay:GO:0006335 DNA replication-dependent chromatin assembly [PMID:9030687]
experiment: EXISTENCE:direct assay:GO:0033186 CAF-1 complex [PMID:9030687]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:16503640]
experiment: EXISTENCE:mutant phenotype:GO:0006335 DNA replication-dependent chromatin assembly [PMID:9030688]
note: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1); chromatin assembly by CAF-1 is important for multiple processes including histone H3/H4 tetramerization, silencing at telomeres, mating type loci and rDNA, maintenance of kinetochore structure, deactivation of DNA damage checkpoint after DNA repair, chromatin dynamics during transcription, and repression of divergent noncoding transcription
codon start: 1
product: Rlf2p
translation: MEQHLKSIPLQDDTKKKGILSFFQNTTTVKSNKFLTKEKDVITLDDPKEDVSGPMIETVKQETMKSINKECADEMKTTPKKANAEDKLLCYKNSPIQSTKYDRNTNKQVPNGNIIAIETKSRSSSPCSKRELSSSKKEEAKREKELKKQQRAEEKHRKELLRQEEKKKKELKVEEERQRRAELKKQKEEEKRRKEEARLEAKRRKEEERLKKEEEIRLKEEAKERAQSRIGNFFKKLSDSNTPVVEKSDYEKFFLPFYAKDGVRVSNKWKLTKVELEGSKRKIDDELLNSKDKTSSDDLLNWLQSRRLPRGHKIKRKAVDVLQQMPLKEKTDDELQSLLAQVPHKYIKFYENVRPPFIGTYSMDFTLPPNDPFSTKGTGFNYDYDSDVEWVNEEEEGEVDNLESGEEEEEEEDDEDVPSEGEFDGFLDSEENSDLDGLPCAKRKFVGPLIPTICLKSNFENLSEENKRYLQQLKAEVIIETDGPIDPFKEPKTSSLPSKRSNSDLQAQTASQSQSPEKKQKAMITDPMDLLRLFDGVQDSTFSLGTVTEIAQKNLPQYNKQTIKNTIKEYAIRSSGKGDLPRKWVIKDAQNWENLRANANMPTPSL
SIO_010081: YPR018W
subclass of: SO_0000673
so part of: YPR018W
location: 594476..596296
location: region:594476-596296:1
so has part: feature:594476-596296:1:exon

NP_015343.1
type: Protein
SIO_000068: ncbiprotein

S000006222
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:594476-596296:1:exon

YPR019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC54
alternative label: HCD21
gene: MCM4
locus tag: YPR019W
gene synonym: CDC54; HCD21
so part of: sequence
location: <596750..>599551
location: region:596750-599551:1
so has part: feature:596750-599551:1:exon
subclass of: SO_0000010

856130
type: Gene
SIO_000068: ncbigene

position:596750:1
position: 596750
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:599551:1
position: 599551
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:596750-599551:1:exon

YPR019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC54
alternative label: HCD21
gene: MCM4
locus tag: YPR019W
gene synonym: CDC54; HCD21
product: MCM DNA helicase complex subunit MCM4
transcript id: NM_001184116.1
SIO_010081: YPR019W
subclass of: SO_0000673
so part of: YPR019W
location: <596750..>599551
location: region:596750-599551:1
so has part: feature:596750-599551:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:596750-599551:1:exon

YPR019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC54
alternative label: HCD21
gene: MCM4
locus tag: YPR019W
gene synonym: CDC54; HCD21
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0003678 DNA helicase activity [PMID:15723534]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:11756674|PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10559985|PMID:10704410]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194|PMID:9335335]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10559985|PMID:10704410]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0006268 DNA unwinding involved in DNA replication [PMID:15723534|PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0009378 four-way junction helicase activity [PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0017116 single-stranded DNA helicase activity [PMID:18657510|PMID:15723534]
experiment: EXISTENCE:direct assay:GO:0031261 DNA replication preinitiation complex [PMID:9554851]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0042555 MCM complex [PMID:12480933]
experiment: EXISTENCE:direct assay:GO:0043138 3'-5' DNA helicase activity [PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:16103218]
experiment: EXISTENCE:direct assay:GO:0071162 CMG complex [PMID:26524492]
experiment: EXISTENCE:direct assay:GO:0097373 MCM core complex [PMID:13679365]
experiment: EXISTENCE:genetic interaction:GO:0006270 DNA replication initiation [PMID:2044962]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0003697 single-stranded DNA binding [PMID:17895243]
experiment: EXISTENCE:mutant phenotype:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10834843]
experiment: EXISTENCE:mutant phenotype:GO:0033260 nuclear DNA replication [PMID:2044962]
experiment: EXISTENCE:mutant phenotype:GO:0034214 protein hexamerization [PMID:31385807]
note: Essential helicase component of heterohexameric MCM2-7 complexes; MCM2-7 complexes bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p
codon start: 1
product: MCM DNA helicase complex subunit MCM4
translation: MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSSSSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV
SIO_010081: YPR019W
subclass of: SO_0000673
so part of: YPR019W
location: 596750..599551
location: region:596750-599551:1
so has part: feature:596750-599551:1:exon

NP_015344.1
type: Protein
SIO_000068: ncbiprotein

S000006223
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:596750-599551:1:exon

YPR020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATP20
locus tag: YPR020W
so part of: sequence
location: <599870..>600217
location: region:599870-600217:1
so has part: feature:599870-600217:1:exon
subclass of: SO_0000010

856131
type: Gene
SIO_000068: ncbigene

position:599870:1
position: 599870
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:600217:1
position: 600217
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:599870-600217:1:exon

YPR020W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATP20
locus tag: YPR020W
product: F1F0 ATP synthase subunit g
transcript id: NM_001184117.1
SIO_010081: YPR020W
subclass of: SO_0000673
so part of: YPR020W
location: <599870..>600217
location: region:599870-600217:1
so has part: feature:599870-600217:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:599870-600217:1:exon

YPR020W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATP20
locus tag: YPR020W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0015986 proton motive force-driven ATP synthesis [PMID:20691145]
experiment: EXISTENCE:direct assay:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:20691145]
experiment: EXISTENCE:mutant phenotype:GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [PMID:10336613]
experiment: EXISTENCE:mutant phenotype:GO:0015986 proton motive force-driven ATP synthesis [PMID:10336613|PMID:9857174]
experiment: EXISTENCE:mutant phenotype:GO:0042407 cristae formation [PMID:19528297]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:16551625|PMID:17761666|PMID:20219971]
note: Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex, which in turn determines oligomerization of the complex and the shape of inner membrane cristae
codon start: 1
product: F1F0 ATP synthase subunit g
translation: MLSRIQNYTSGLVSKANLLSSKALYYGKVGAEISKQIYLKEGLQPPTVAQFKSVYSNLYKQSLNFALKPTEVLSCLKNIQKNELLKYGAYGIQLIGFYSVGEIIGRRKLVGYKHH
SIO_010081: YPR020W
subclass of: SO_0000673
so part of: YPR020W
location: 599870..600217
location: region:599870-600217:1
so has part: feature:599870-600217:1:exon

NP_015345.1
type: Protein
SIO_000068: ncbiprotein

S000006224
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:599870-600217:1:exon

YPR021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AGC1
locus tag: YPR021C
so part of: sequence
location: complement(<600649..>603357)
location: region:600649-603357:-1
so has part: feature:600649-603357:-1:exon
subclass of: SO_0000010

856132
type: Gene
SIO_000068: ncbigene

position:600649:-1
position: 600649
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:603357:-1
position: 603357
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:600649-603357:-1:exon

YPR021C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AGC1
locus tag: YPR021C
product: citrin
transcript id: NM_001184118.1
SIO_010081: YPR021C
subclass of: SO_0000673
so part of: YPR021C
location: complement(<600649..>603357)
location: region:600649-603357:-1
so has part: feature:600649-603357:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:600649-603357:-1:exon

YPR021C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AGC1
locus tag: YPR021C
experiment: EXISTENCE:direct assay:GO:0005313 L-glutamate transmembrane transporter activity [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0015183 L-aspartate transmembrane transporter activity [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:0015292 uniporter activity [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:0015297 antiporter activity [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:0015810 aspartate transmembrane transport [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:0015813 L-glutamate transmembrane transport [PMID:14622413]
experiment: EXISTENCE:direct assay:GO:1990816 vacuole-mitochondrion membrane contact site [PMID:25026036]
experiment: EXISTENCE:mutant phenotype:GO:0044271 cellular nitrogen compound biosynthetic process [PMID:14622413]
note: Mitochondrial amino acid transporter; acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis; human homolog SLC25A13 complements yeast null mutant
codon start: 1
product: citrin
translation: MEQINSNSRKKKQQLEVFKYFASVLTKEDKPISISNGMLDMPTVNSSKLTAGNGKPDTEKLTGELILTYDDFIELISSSKTIYSKFTDHSFNLNQIPKNVFGCIFFAIDEQNKGYLTLNDWFYFNNLLEYDNYHLIILYEFFRKFDVENLKAKQKKELGSSSFNLKAADDRIKSINYGNRFLSFDDLLLNLNQFKDTIRLLHESIDDNFVKDNKLLLDWNDFRFLKFYKCYHENEEYLSLNSLVTILQNDLKNEKIFIGFDRLAQMDSQGHRLALSKNQLTYLLRLFYSHRVSADIFSSLNLSNTELLKADNNSIPYNVFKDIFYLFQNFDLLNQIFHKYVTENNLNEQDIREQIVTKNDFMTVLNAQYNKVNNIIEFSPSQINLLFSIVANSKENRRLRKRNQDRDDELLNDHHYDSDIDFFIHNEYLHGVSRSRKNLESFNDYYHDLSDGFDQDSGVKKASKASTGLFESVFGGKKDKATMRSDLTIEDFMKILNPNYLNDLVHQMELQKNQNESLYINYYFYPIFDSLYNFSLGSIAGCIGATVVYPIDFIKTRMQAQRSLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDKNGKLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGETKYNGIFHAIRTILKEESFRSFFKGGGARVLRSSPQFGFTLAAYELFKGFIPSPDNKLKSREGRKRFCIDDDAGNEETVVHSNGELPQQKFYSDDRKHANYYYKSCQIAKTFIDLDNNFSRFDSSVYKNFQEHLRSING
SIO_010081: YPR021C
subclass of: SO_0000673
so part of: YPR021C
location: complement(600649..603357)
location: region:600649-603357:-1
so has part: feature:600649-603357:-1:exon

NP_015346.1
type: Protein
SIO_000068: ncbiprotein

S000006225
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:600649-603357:-1:exon

YPR022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SDD4
locus tag: YPR022C
so part of: sequence
location: complement(<603911..>607312)
location: region:603911-607312:-1
so has part: feature:603911-607312:-1:exon
subclass of: SO_0000010

856133
type: Gene
SIO_000068: ncbigene

position:603911:-1
position: 603911
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:607312:-1
position: 607312
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:603911-607312:-1:exon

YPR022C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SDD4
locus tag: YPR022C
product: Sdd4p
transcript id: NM_001184119.1
SIO_010081: YPR022C
subclass of: SO_0000673
so part of: YPR022C
location: complement(<603911..>607312)
location: region:603911-607312:-1
so has part: feature:603911-607312:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:603911-607312:-1:exon

YPR022C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SDD4
locus tag: YPR022C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
note: Putative transcription factor, as suggested by computational analysis; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS; overproduction of a truncation allele suppresses lethality due to expression of the dominant PET9 allele AAC2-A128P
codon start: 1
product: Sdd4p
translation: MHGKELAGRLRKRENDNDLSPNSSSSPAERFRCPHPECNKTFSRQEHLSRHKLNHWPKEIYVCSYVLPTTNAPCNKTFVRKDLLIRHEKRHSKVKNRLSRPSKDQISSSNKDFSKNAPYNPSEVPLSTQSGTSTINLIKNSVNPPPSITQESKFRPFLQQAQQPQQVQQSQQPQQIQQLQQLQFPQQLRAPLQQPMLQQQMHPQQASPTFPSYDPRIRNNGQNGNQFFNLIFDNRTGVNGFEVDAANNNGNGNDQNMNINPAVQQQRYQDRNFASSSYQQPLQPLTQDQQQEQYFQQQKLAQQQQQQQQQQQQQQQLPPQNPFGDPLTSSSSGANLSVMQDLFSTNFLNSDPLQSFMQELSEAPQVSIEDTFSDKNTIPPNEKPVQQDEGFQNPPVMFELPQDNIKIPKAQPKFNDNPSTSVKDNLSSQKLNINELKRRSSKDSGVGNNSSLNYKEQLRHSMKSVPSFFHPDPLTKYKISKEKCQEMFSFVPELRYVSIESIHKSLKSFWLNFHPQYGLLHKPSFHVDKQPAILNLALIMTGASFLGSEYREQISDPICGPLRWIIFSHADFQPPSKTYIIQSLLLVEGYEKTSTNRYLHERSFLHHGTTIQLLRRTPSLGGHPLMVKTGKTSGENSIQDPQEVYKRWIDFEMLKRIAFYAFYMDTTHAVVFGYWNLFINSNQIQLTLPCPDQVWESYDLSYETLMEHGYGSTKRDENNTFLSALMQLMKNVIQILRNNNIRRNKVNNGGIESTPTDLESTTDWNIQSLFGKKILLAGIISILFQCQEEVNGDYFITNFRGGITDHLGLSWKDILSFAMNYWLHEVQKSCTDPKACRISTPSEETLTNRKIDEDNGDGLCDDDLDLLSSDNPSNCKIPVIHISQIVLRILHHDYYIYAGAPWRMNVPIGRDEYDMISRRILQFAKDPYNGGVAVVYAFQFLFEMFIIKENNVPTVVKSYNINSDPVITRPYAIALTSLLIWSCNFALHGCEVSIWDNTEASKDECFQPDDSNGGNILGNTDNNGSTIANNNLKEKNNYIPIESFEVYLLRMYRNLYVDSSLDVVSFQNDVWAKASLLQHISNTHFLCGMMQFMRDIFNKSYWDLGREFGKLFDNCLERSLGKTSPTCHNMFDV
SIO_010081: YPR022C
subclass of: SO_0000673
so part of: YPR022C
location: complement(603911..607312)
location: region:603911-607312:-1
so has part: feature:603911-607312:-1:exon

NP_015347.1
type: Protein
SIO_000068: ncbiprotein

S000006226
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:603911-607312:-1:exon

YPR023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EAF3
locus tag: YPR023C
so part of: sequence
location: complement(<608826..>610031)
location: region:608826-610031:-1
so has part: feature:608826-610031:-1:exon
subclass of: SO_0000010

856134
type: Gene
SIO_000068: ncbigene

position:608826:-1
position: 608826
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:610031:-1
position: 610031
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:608826-610031:-1:exon

YPR023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EAF3
locus tag: YPR023C
product: Eaf3p
transcript id: NM_001184120.1
SIO_010081: YPR023C
subclass of: SO_0000673
so part of: YPR023C
location: complement(<608826..>610031)
location: region:608826-610031:-1
so has part: feature:608826-610031:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:608826-610031:-1:exon

YPR023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EAF3
locus tag: YPR023C
experiment: EXISTENCE:direct assay:GO:0000123 histone acetyltransferase complex [PMID:11036083]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:16135807]
experiment: EXISTENCE:direct assay:GO:0032221 Rpd3S/Clr6-CII complex [PMID:16286007|PMID:16286008]
experiment: EXISTENCE:direct assay:GO:0035064 methylated histone binding [PMID:16364921]
experiment: EXISTENCE:direct assay:GO:0035267 NuA4 histone acetyltransferase complex [PMID:15485911]
experiment: EXISTENCE:genetic interaction:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:19948887]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:11036083]
experiment: EXISTENCE:mutant phenotype:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:19417103]
experiment: EXISTENCE:mutant phenotype:GO:0043487 regulation of RNA stability [PMID:31694990]
experiment: EXISTENCE:mutant phenotype:GO:0045892 negative regulation of DNA-templated transcription [PMID:16364921]
experiment: EXISTENCE:mutant phenotype:GO:0060195 negative regulation of antisense RNA transcription [PMID:21248844]
note: Component of the Rpd3S histone deacetylase complex; Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition
codon start: 1
product: Eaf3p
translation: MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLEQQKKKKLSTSLGGPSNGGKRKGDSRSNASISKSTSQSFLTSSVSGRKSGRSSANSLHPGSSLRSSSDQNGNDDRRRSSSLSPNMLHHIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVALGM
SIO_010081: YPR023C
subclass of: SO_0000673
so part of: YPR023C
location: complement(608826..610031)
location: region:608826-610031:-1
so has part: feature:608826-610031:-1:exon

NP_015348.1
type: Protein
SIO_000068: ncbiprotein

S000006227
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:608826-610031:-1:exon

YPR024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OSD1
alternative label: YTA11
gene: YME1
locus tag: YPR024W
gene synonym: OSD1; YTA11
so part of: sequence
location: <610481..>612724
location: region:610481-612724:1
so has part: feature:610481-612724:1:exon
subclass of: SO_0000010

856135
type: Gene
SIO_000068: ncbigene

position:610481:1
position: 610481
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:612724:1
position: 612724
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:610481-612724:1:exon

YPR024W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OSD1
alternative label: YTA11
gene: YME1
locus tag: YPR024W
gene synonym: OSD1; YTA11
product: i-AAA protease YME1
transcript id: NM_001184121.1
SIO_010081: YPR024W
subclass of: SO_0000673
so part of: YPR024W
location: <610481..>612724
location: region:610481-612724:1
so has part: feature:610481-612724:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:610481-612724:1:exon

YPR024W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OSD1
alternative label: YTA11
gene: YME1
locus tag: YPR024W
gene synonym: OSD1; YTA11
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:8688560]
experiment: EXISTENCE:direct assay:GO:0031942 i-AAA complex [PMID:16267274]
experiment: EXISTENCE:direct assay:GO:0045041 protein import into mitochondrial intermembrane space [PMID:16966379]
experiment: EXISTENCE:genetic interaction:GO:0004176 ATP-dependent peptidase activity [PMID:8688560]
experiment: EXISTENCE:mutant phenotype:GO:0004176 ATP-dependent peptidase activity [PMID:15772085]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:22993211]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:18843051]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:27398316]
experiment: EXISTENCE:mutant phenotype:GO:0045041 protein import into mitochondrial intermembrane space [PMID:16966379]
experiment: EXISTENCE:mutant phenotype:GO:0051604 protein maturation [PMID:16966379]
note: Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant
codon start: 1
product: i-AAA protease YME1
translation: MNVSKILVSPTVTTNVLRIFAPRLPQIGASLLVQKKWALRSKKFYRFYSEKNSGEMPPKKEADSSGKASNKSTISSIDNSQPPPPSNTNDKTKQANVAVSHAMLATREQEANKDLTSPDAQAAFYKLLLQSNYPQYVVSRFETPGIASSPECMELYMEALQRIGRHSEADAVRQNLLTASSAGAVNPSLASSSSNQSGYHGNFPSMYSPLYGSRKEPLHVVVSESTFTVVSRWVKWLLVFGILTYSFSEGFKYITENTTLLKSSEVADKSVDVAKTNVKFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSENWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLDKLKTSTNTVVEGPDSDERKDIGDDKPKIPTMLNA
SIO_010081: YPR024W
subclass of: SO_0000673
so part of: YPR024W
location: 610481..612724
location: region:610481-612724:1
so has part: feature:610481-612724:1:exon

NP_015349.1
type: Protein
SIO_000068: ncbiprotein

S000006228
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:610481-612724:1:exon

YPR025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CCL1
locus tag: YPR025C
so part of: sequence
location: complement(<613377..>614558)
location: region:613377-614558:-1
so has part: feature:613377-614558:-1:exon
subclass of: SO_0000010

856136
type: Gene
SIO_000068: ncbigene

position:613377:-1
position: 613377
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:614558:-1
position: 614558
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:613377-614558:-1:exon

YPR025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CCL1
locus tag: YPR025C
product: TFIIH complex kinase subunit CCL1
transcript id: NM_001184122.1
SIO_010081: YPR025C
subclass of: SO_0000673
so part of: YPR025C
location: complement(<613377..>614558)
location: region:613377-614558:-1
so has part: feature:613377-614558:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:613377-614558:-1:exon

YPR025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CCL1
locus tag: YPR025C
experiment: EXISTENCE:direct assay:GO:0005675 transcription factor TFIIH holo complex [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:19450536|PMID:19679665|PMID:11839796]
experiment: EXISTENCE:direct assay:GO:0070985 transcription factor TFIIK complex [PMID:11839796|PMID:19818408]
experiment: EXISTENCE:genetic interaction:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:8230216]
experiment: EXISTENCE:mutant phenotype:GO:0006995 cellular response to nitrogen starvation [PMID:26567215]
experiment: EXISTENCE:mutant phenotype:GO:0010508 positive regulation of autophagy [PMID:26567215]
experiment: EXISTENCE:mutant phenotype:GO:1905866 positive regulation of Atg1/ULK1 kinase complex assembly [PMID:26567215]
note: Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p; regulates the activity of Kin28p, a TFIIH-associated carboxy-terminal domain (CTD) kinase that facilitates recruitment of mRNA 5'-capping and polyadenylation factors to the RNAPII holoenzyme complex, and has a minor role in RNAPII transcription; subunit of TFIIK, a TFIIH subassembly; human homolog CCNH allows growth of a yeast ccl1 temperature-sensitive mutant at restrictive temperature
codon start: 1
product: TFIIH complex kinase subunit CCL1
translation: MTDIQLNGKSTLDTPSATMSAKEKEAKLKSADENNKPPNYKRISDDDLYRHSSQYRMWSYTKDQLQEKRVDTNARAIAYIEENLLKFREAHNLTEEEIKVLEAKAIPLTMEEELDLVNFYAKKVQVIAQHLNLPTEVVATAISFFRRFFLENSVMQIDPKSIVHTTIFLACKSENYFISVDSFAQKAKSTRDSVLKFEFKLLESLKFSLLNHHPYKPLHGFFLDIQNVLYGKVDLNYMGQIYDRCKKRITAALLTDVVYFYTPPQITLATLLIEDEALVTRYLETKFPSREGSQESVPGNEKEEPQNDASTTEKNKEKSTESEEYSIDSAKLLTIIRECKSIIEDCKPPSTEEAKKIAAKNYYCQNPSTLIQKLKRKLNGEDTSSTVEKKQKT
SIO_010081: YPR025C
subclass of: SO_0000673
so part of: YPR025C
location: complement(613377..614558)
location: region:613377-614558:-1
so has part: feature:613377-614558:-1:exon

NP_015350.1
type: Protein
SIO_000068: ncbiprotein

S000006229
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:613377-614558:-1:exon

YPR026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATH1
locus tag: YPR026W
so part of: sequence
location: <615379..>619014
location: region:615379-619014:1
so has part: feature:615379-619014:1:exon
subclass of: SO_0000010

856137
type: Gene
SIO_000068: ncbigene

position:615379:1
position: 615379
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:619014:1
position: 619014
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:615379-619014:1:exon

YPR026W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATH1
locus tag: YPR026W
product: alpha,alpha-trehalase ATH1
transcript id: NM_001184123.1
SIO_010081: YPR026W
subclass of: SO_0000673
so part of: YPR026W
location: <615379..>619014
location: region:615379-619014:1
so has part: feature:615379-619014:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:615379-619014:1:exon

YPR026W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATH1
locus tag: YPR026W
EC number: 3.2.1.28
experiment: EXISTENCE:direct assay:GO:0005993 trehalose catabolic process [PMID:8764988]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:15128531]
experiment: EXISTENCE:direct assay:GO:0030287 cell wall-bounded periplasmic space [PMID:15128531]
experiment: EXISTENCE:mutant phenotype:GO:0000324 fungal-type vacuole [PMID:7502577]
experiment: EXISTENCE:mutant phenotype:GO:0004555 alpha,alpha-trehalase activity [PMID:7502577]
experiment: EXISTENCE:mutant phenotype:GO:0005993 trehalose catabolic process [PMID:7502577|PMID:8764988]
experiment: EXISTENCE:mutant phenotype:GO:0015771 trehalose transport [PMID:19016884]
note: Acid trehalase required for utilization of extracellular trehalose; involved in intracellular trehalose degradation during growth recovery after saline stress
codon start: 1
product: alpha,alpha-trehalase ATH1
translation: MKRIRSLWFNAEASYSNLNNSPSLRNKNSTGNNSRSKNYRSFSRFDLINSILLLMMLFLLAIFVTALYLTKSSRLTYSHASRAALFNPLGVISPSLGNHTLNYDPEARESSKKLYELLSDFNTAYYDDENMILGSNLFSKNTYSRQPYVANGYIGSRIPNIGFGYALDTLNFYTDAPGALNNGWPLRNHRFAGAFVSDFYCLQPKLNSTNFPELDDVGYSTVISSIPQWTNLQFSLVNDSKWFNPQNVTLDDVTNYSQNLSMKDGIVTTELDWLNSQIHVKSEIWAHRHIHPLGVVSLEISLNTDHLPSDFDSLDVNIWDILDFNTSHRTVLHSTGTDEKNNAVFMIVQPDNVPSSNCAIYSTCTVKYENSTNPINSSESFEEKDVSSNIYNVILTEDQPKIIVHKYVGIMSTEFNKNKEQQDNTNIGLAKMIALNSKGNYEKLLSSHKRAWYDLYNDAFIEIPSDSLLEMTARSSLFHLLANTRDYNVSSDRGLPVGVSGLSSDSYGGMVFWDADIWMEPALLPFFPNVAQNMNNYRNATHSQAKLNAEKYGYPGAIYPWTSGKYANCTSTGPCVDYEYHINVDVAMASFSIYLNGHEGIDDEYLRYTTWPIIKNAAQFFTAYVKYNSSLGLYETYNLTDPDEFANHINNGAFTNAGIKTLLKWATDIGNHLGEVVDPKWSEISKDIYIPRSSSNITLEYSGMNSSVEIKQADVTLMVYPLGYINDESILNNAIKDLYYYSERQSASGPAMTYPVFVAAAAGLLNHGSSSQSYLYKSVLPYLRAPFAQFSEQSDDNFLTNGLTQPAFPFLTANGGFLQSILFGLTGIRYSYEVDPDTKKINRLLRFNPIELPLLPGGIAIRNFKYMNQVLDIIIDDHNGTIVHKSGDVPIHIKIPNRSLIHDQDINFYNGSENERKPNLERRDVDRVGDPMRMDRYGTYYLLKPKQELTVQLFKPGLNARNNIAENKQITNLTAGVPGDVAFSALDGNNYTHWQPLDKIHRAKLLIDLGEYNEKEITKGMILWGQRPAKNISISILPHSEKVENLFANVTEIMQNSGNDQLLNETIGQLLDNAGIPVENVIDFDGIEQEDDESLDDVQALLHWKKEDLAKLIEQIPRLNFLKRKFVKILDNVPVSPSEPYYEASRNQSLIEILPSNRTTFTIDYDKLQVGDKGNTDWRKTRYIVVAVQGVYDDYDDDNKGATIKEIVLND
SIO_010081: YPR026W
subclass of: SO_0000673
so part of: YPR026W
location: 615379..619014
location: region:615379-619014:1
so has part: feature:615379-619014:1:exon

NP_015351.1
type: Protein
SIO_000068: ncbiprotein

S000006230
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:615379-619014:1:exon

YPR027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR027C
so part of: sequence
location: complement(<620425..>621258)
location: region:620425-621258:-1
so has part: feature:620425-621258:-1:exon
subclass of: SO_0000010

856138
type: Gene
SIO_000068: ncbigene

position:620425:-1
position: 620425
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:621258:-1
position: 621258
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:620425-621258:-1:exon

YPR027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR027C
product: uncharacterized protein
transcript id: NM_001184124.1
SIO_010081: YPR027C
subclass of: SO_0000673
so part of: YPR027C
location: complement(<620425..>621258)
location: region:620425-621258:-1
so has part: feature:620425-621258:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:620425-621258:-1:exon

YPR027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR027C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum, while the mCherry fusion protein localizes to the vacuole
codon start: 1
product: uncharacterized protein
translation: MVGIYRILASFVPLLGLLFAFHDDDMIDTVTIIKTVYETVTSTSTAPAPAATKSVSEKKLDDTKLTLQVIQTMVSCFSVGENPANMISCGLGVVILMFSLIIELINKLENDGINEPQRLYDLIKPKYVELPSNYVNEKIKTTFEPLDLYLGVNMNTSGSELNQNCLILKLGEKTALPFPGLAQQICYTKGASNEFTNYKLSDIQGNLNENSQGIANGVFQKISNIRKISGNFKSQLYQISEKITDENWDGSAVGFTAHGREKGPNKSQISVSFYRDN
SIO_010081: YPR027C
subclass of: SO_0000673
so part of: YPR027C
location: complement(620425..621258)
location: region:620425-621258:-1
so has part: feature:620425-621258:-1:exon

NP_015352.1
type: Protein
SIO_000068: ncbiprotein

S000006231
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:620425-621258:-1:exon

YNCP0011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCP0011C
so part of: sequence
location: complement(622540..622631)
location: region:622540-622631:-1
so has part: feature:622540-622631:-1:exon
subclass of: SO_0000663

856139
type: Gene
SIO_000068: ncbigene

position:622540:-1
position: 622540
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:622631:-1
position: 622631
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:622540-622631:-1:exon

YNCP0011C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCP0011C
product: tRNA-Phe
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Phenylalanine tRNA (tRNA-Phe), predicted by tRNAscan-SE analysis
SIO_010081: YNCP0011C
subclass of: SO_0000673
so part of: YNCP0011C
location: complement(join(622540..622575,622595..622631))
location: region:622540-622631:-1
so has part: feature:622595-622631:-1:exon
so has part: feature:622540-622575:-1:exon

S000006571
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:622595-622631:-1:exon

position:622595:-1
position: 622595
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:622540-622575:-1:exon

position:622575:-1
position: 622575
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPR028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIP2
gene: YOP1
locus tag: YPR028W
gene synonym: YIP2
so part of: sequence
location: <623527..>624202
location: region:623527-624202:1
so has part: feature:623527-624202:1:exon
subclass of: SO_0000010

856140
type: Gene
SIO_000068: ncbigene

position:623527:1
position: 623527
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:624202:1
position: 624202
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:623527-624202:1:exon

YPR028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YIP2
gene: YOP1
locus tag: YPR028W
gene synonym: YIP2
product: Yop1p
transcript id: NM_001184125.1
SIO_010081: YPR028W
subclass of: SO_0000673
so part of: YPR028W
location: join(<623527..623577,623711..>624202)
location: region:623527-624202:1
so has part: feature:623527-623577:1:exon
so has part: feature:623711-624202:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:623527-623577:1:exon

position:623577:1
position: 623577
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:623711-624202:1:exon

position:623711:1
position: 623711
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPR028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YIP2
gene: YOP1
locus tag: YPR028W
gene synonym: YIP2
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:16469703|PMID:22842922|PMID:26928762|PMID:27831485]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11278413]
experiment: EXISTENCE:direct assay:GO:0071782 endoplasmic reticulum tubular network [PMID:16469703]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0007029 endoplasmic reticulum organization [PMID:19665976]
experiment: EXISTENCE:genetic interaction:GO:0032581 ER-dependent peroxisome organization [PMID:27129769]
experiment: EXISTENCE:genetic interaction:GO:0034976 response to endoplasmic reticulum stress [PMID:27117666]
experiment: EXISTENCE:genetic interaction:GO:0048309 endoplasmic reticulum inheritance [PMID:27117666]
experiment: EXISTENCE:genetic interaction:GO:0051292 nuclear pore complex assembly [PMID:19273614]
experiment: EXISTENCE:genetic interaction:GO:0071786 endoplasmic reticulum tubular network organization [PMID:16469703|PMID:18442980|PMID:18309084]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:11278413|PMID:12427979]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:11278413]
note: Reticulon-interacting protein; ER integral membrane protein involved in the generation of tubular ER morphology; promotes membrane curvature; forms tubules in vitro; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; interacts with Yip1p to mediate membrane traffic and with Sey1p to maintain ER morphology; facilitates lipid exchange between the ER and mitochondria; forms ER foci upon DNA replication stress
codon start: 1
product: Yop1p
translation: MSEYASSIHSQMKQFDTKYSGNRILQQLENKTNLPKSYLVAGLGFAYLLLIFINVGGVGEILSNFAGFVLPAYLSLVALKTPTSTDDTQLLTYWIVFSFLSVIEFWSKAILYLIPFYWFLKTVFLIYIALPQTGGARMIYQKIVAPLTDRYILRDVSKTEKDEIRASVNEASKATGASVH
SIO_010081: YPR028W
subclass of: SO_0000673
so part of: YPR028W
location: join(623527..623577,623711..624202)
location: region:623527-624202:1
so has part: feature:623527-623577:1:exon
so has part: feature:623711-624202:1:exon

NP_015353.1
type: Protein
SIO_000068: ncbiprotein

S000006232
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:623527-623577:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:623711-624202:1:exon

YPR029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: APL4
locus tag: YPR029C
so part of: sequence
location: complement(<624469..>626967)
location: region:624469-626967:-1
so has part: feature:624469-626967:-1:exon
subclass of: SO_0000010

856141
type: Gene
SIO_000068: ncbigene

position:624469:-1
position: 624469
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:626967:-1
position: 626967
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:624469-626967:-1:exon

YPR029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: APL4
locus tag: YPR029C
product: Apl4p
transcript id: NM_001184126.1
SIO_010081: YPR029C
subclass of: SO_0000673
so part of: YPR029C
location: complement(<624469..>626967)
location: region:624469-626967:-1
so has part: feature:624469-626967:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:624469-626967:-1:exon

YPR029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: APL4
locus tag: YPR029C
experiment: EXISTENCE:direct assay:GO:0030121 AP-1 adaptor complex [PMID:10564262]
experiment: EXISTENCE:direct assay:GO:0030276 clathrin binding [PMID:11489214]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:17003107]
note: Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
codon start: 1
product: Apl4p
translation: MGSSLRSFIKDVRGAKTLADERAIITKQSAKIRTKLRDDHLPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHPNKYAVSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKKALQCAAKLIFKDVSLLEIFNIEDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPLSLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSNNVLDYKDNFCDLLTRIATNTDSTKNSGQAILYETVKTIFSLDLNQPLRVLGINILAKFLAGKDNNTKYVSLNTLLKVVPQEPTAVQRHRKFISHCLQDTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLIIYTIDHLIDTFDTRVVKDESWKLDVFFNILKLVGSFINYEKINDILIIINNTSQLSDKSEFLRKMLTISLNGTSAEISEENIGWQLVLIWCIGEYGDLVLNEGNKNGADIINESSITDYLLTLQELYTATNLKIINYILTAALKLSVRFHDAKNIEKLRQLILSYTDSTDLSLQMKSNQYEIFFNQSISVKKIILETMPKFEKITEEQDNGKALSKNLISNEPVDLLSDLLGEDSKAESKASTGDNVKPIDILEEIFGEKNDIAQVPKNANKEESINHSSAVEANSGVTLPLDANKIYDSSSLNVYASLLSANSGLAHLDLYFQAKSLISDLKTFCAVPKAQKLTLGQLYPSSTINASQICKQSLKISGSGKLKLRVKLDFHLNGSSSITNEQFDHKFDETL
SIO_010081: YPR029C
subclass of: SO_0000673
so part of: YPR029C
location: complement(624469..626967)
location: region:624469-626967:-1
so has part: feature:624469-626967:-1:exon

NP_015354.1
type: Protein
SIO_000068: ncbiprotein

S000006233
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:624469-626967:-1:exon

YPR030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ART8
alternative label: MRG19
gene: CSR2
locus tag: YPR030W
gene synonym: ART8; MRG19
so part of: sequence
location: <627880..>631245
location: region:627880-631245:1
so has part: feature:627880-631245:1:exon
subclass of: SO_0000010

856142
type: Gene
SIO_000068: ncbigene

position:627880:1
position: 627880
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:631245:1
position: 631245
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:627880-631245:1:exon

YPR030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ART8
alternative label: MRG19
gene: CSR2
locus tag: YPR030W
gene synonym: ART8; MRG19
product: Csr2p
transcript id: NM_001184127.1
SIO_010081: YPR030W
subclass of: SO_0000673
so part of: YPR030W
location: <627880..>631245
location: region:627880-631245:1
so has part: feature:627880-631245:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:627880-631245:1:exon

YPR030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ART8
alternative label: MRG19
gene: CSR2
locus tag: YPR030W
gene synonym: ART8; MRG19
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12444972]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:12444972]
experiment: EXISTENCE:genetic interaction:GO:0031505 fungal-type cell wall organization [PMID:10679005]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:12444972]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:18976803]
note: Nuclear ubiquitin protein ligase binding protein; may regulate utilization of nonfermentable carbon sources and endocytosis of plasma membrane proteins; overproduction suppresses chs5 spa2 lethality at high temp; ubiquitinated by Rsp5p, deubiquitinated by Ubp2p; CSR2 has a paralog, ECM21, that arose from the whole genome duplication
codon start: 1
product: Csr2p
translation: MQSTVPIAIASNGNKRDVVQNVSAGDEGDILQRLARNREMISTSLSPQKSSGFSGRRRSSSVRDALSSFFGTGNSPTSSMDDYSNLMNRNYSTASTAMCRGNSFPSDVGTKAYNITGSYQPDRHRNSVPYTTIDQLHTRQDTGLRRESDPVAAKQISSNNDIVRSFITHHASNSTMFINRVLSDYLADRGFIKQTPLYNKKSVLEISIATSAESVFLPTTKSDETEYLSLIHGSLNQARTQPVGSTNTAESDFLPSCPTMDTLNENNDLSLFPLHTQRTSPSNTARTGNAMDTSNSDRASPASNNNTTDADSFVASGNNNPMNNNNSPARNRHPNSHSRSLPNAWNSQMPSFSFALIFSLNKSTTLSDIKVELTSNVRVVWFNGLPPTKNVNEECYNIGSLDWTLNADNFNLFIPQGAKSPLDIVENHSNNRKLKVLQKLSMRKRRSFSNKAVLRENILNNLNASNSTNKLNAGVYVFTIPIVLASRIPESLYYPSARVSYSLRLATKLKDEHTQLVASRPRSSSISSPQKLRSYSCSDSYEYSQIDDTIEGETYNNDKNSTGKIAFPSSWLKSAKGRLKRNNSNGRSDNNGASSSGLAMQHDSEDTINLQYPLNLVRTPPEISVTTANKPLYINKVWENCLSYEISFAQKYVPLNGEIPITIKVAPLVKSLSVKRIRVSCREKISYRSKDYQYDFDQLDPLASDPCNPYHMRYLVRKKKDRSLPLFEVASKCTSGPSIREEVVTNTVDDNLLAYTSSKENNKDIPFSESFTVKTKLKFPKYCEVDATKAASLPPYGIDLFDPIKDPTQSENTSNNGNVLGFLVGRPNRASKTVHKIPQDKNHNEVNDTNGNSNTSLQTSSNVPIQHYTRLNKPRRGLYLDSMHFKNIQCSHKLEIVLRVSKTDSGSSKIIRHYEVIVDTPIYLISDLCNTSNIDLPTYDMATTESSKVLPPTFEEATSVSASPRSSVSYYPDDISMQQLNLSRSTSLANGYLSTLHPKTTAVSDSSNGAPIRDQQEQQARPLRTEDYALQMGNENNAYSNMDGLLSQDIFEQETAATLFKRDIVTMNFNNNIFTPRYSPRTFTNTDYNYNDNDNNDNDTEGPGPIIHPGPEPPRYDEISS
SIO_010081: YPR030W
subclass of: SO_0000673
so part of: YPR030W
location: 627880..631245
location: region:627880-631245:1
so has part: feature:627880-631245:1:exon

NP_015355.1
type: Protein
SIO_000068: ncbiprotein

S000006234
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:627880-631245:1:exon

YPR031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NTO1
locus tag: YPR031W
so part of: sequence
location: <631515..>633761
location: region:631515-633761:1
so has part: feature:631515-633761:1:exon
subclass of: SO_0000010

856143
type: Gene
SIO_000068: ncbigene

position:631515:1
position: 631515
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:633761:1
position: 633761
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:631515-633761:1:exon

YPR031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NTO1
locus tag: YPR031W
product: Nto1p
transcript id: NM_001184128.1
SIO_010081: YPR031W
subclass of: SO_0000673
so part of: YPR031W
location: <631515..>633761
location: region:631515-633761:1
so has part: feature:631515-633761:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:631515-633761:1:exon

YPR031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NTO1
locus tag: YPR031W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0033100 NuA3 histone acetyltransferase complex [PMID:17157260]
experiment: EXISTENCE:direct assay:GO:0035064 methylated histone binding [PMID:17142463]
experiment: EXISTENCE:direct assay:GO:1990467 NuA3a histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:direct assay:GO:1990468 NuA3b histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:physical interaction:GO:0016573 histone acetylation [PMID:17157260]
note: Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3
codon start: 1
product: Nto1p
translation: MNRGSLDDGPKLREEKHFQDFYPDLNADTLLPFIVPLVETKDNSTDTDSDDISNRNNREIGSVKSVQTKELIFKGRVTTEPLVLKKNEVEFQKCKITTNELKGKKNPYCVRFNESFISRYYHINKVRNRKSYKQQQKEFDGVEAPYFTKFSSKEAPNITISTSTKSAIQKFASISPNLVNFKPQYDMDEQDELYLHYLNKRYFKDQMSHEIFEILMTTLETEWFHIEKHIPSTNSLIARHNILRDCKNYELYGSDDGTGLSMDQACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTGSWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKKMGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAPRGWQTSIEGINKARKYFSLLSTLQTETPQHNEANDRTNSKFNKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKRELTGGTPLTACFENNSLGSLTEEQVQTRIDFANDQLEDLYRLKELTTLVKKRTQASNSLSRSRKKVFDIVKSPQKYLLKINVLDIFIKSEQFKALERLVTEPKLLVILEKCKHCDFDTVQIFKEEIMHFFEVLETLPGASRILQTVSSKAKEQVTNLIGLIEHVDIKKLLSRDFIINDDKIEERPWSGPVIMEEEGLSDAEELSAGEHRMLKLILNSG
SIO_010081: YPR031W
subclass of: SO_0000673
so part of: YPR031W
location: 631515..633761
location: region:631515-633761:1
so has part: feature:631515-633761:1:exon

NP_015356.1
type: Protein
SIO_000068: ncbiprotein

S000006235
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:631515-633761:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1623; Autonomously Replicating Sequence
so part of: sequence
location: 633874..634122
location: region:633874-634122:1
so has part: feature:633874-634122:1:region

S000118419
type: SGD
SIO_000068: sgd

position:633874:1
position: 633874
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:634122:1
position: 634122
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:633874-634122:1:region

YPR032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SNI1
alternative label: SOP1
gene: SRO7
locus tag: YPR032W
gene synonym: SNI1; SOP1
so part of: sequence
location: <634123..>637224
location: region:634123-637224:1
so has part: feature:634123-637224:1:exon
subclass of: SO_0000010

856144
type: Gene
SIO_000068: ncbigene

position:634123:1
position: 634123
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:637224:1
position: 637224
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:634123-637224:1:exon

YPR032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SNI1
alternative label: SOP1
gene: SRO7
locus tag: YPR032W
gene synonym: SNI1; SOP1
product: Rab GTPase-binding protein SRO7
transcript id: NM_001184129.1
SIO_010081: YPR032W
subclass of: SO_0000673
so part of: YPR032W
location: <634123..>637224
location: region:634123-637224:1
so has part: feature:634123-637224:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:634123-637224:1:exon

YPR032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SNI1
alternative label: SOP1
gene: SRO7
locus tag: YPR032W
gene synonym: SNI1; SOP1
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:10402465|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10402465]
experiment: EXISTENCE:direct assay:GO:0031267 small GTPase binding [PMID:16390997]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:22832273]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:10402465]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:10402465]
experiment: EXISTENCE:physical interaction:GO:0000149 SNARE binding [PMID:15964280]
experiment: EXISTENCE:physical interaction:GO:0007264 small GTPase mediated signal transduction [PMID:16390997]
experiment: EXISTENCE:physical interaction:GO:0030010 establishment of cell polarity [PMID:15964280]
note: Effector of Rab GTPase Sec4p; forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; regulates cell proliferation and colony development via the Rho1-Tor1 pathway; homolog of Drosophila lgl tumor suppressor; SRO7 has a paralog, SRO77, that arose from the whole genome duplication
codon start: 1
product: Rab GTPase-binding protein SRO7
translation: MFGSKRLKNVKEAFKSLKGQNSETPIENSKASFKSKNSKTSTISKDAKSSSSLKIPISSNNKNKIFSLAETNKYGMSSKPIAAAFDFTQNLLAIATVTGEVHIYGQQQVEVVIKLEDRSAIKEMRFVKGIYLVVINAKDTVYVLSLYSQKVLTTVFVPGKITSIDTDASLDWMLIGLQNGSMIVYDIDRDQLSSFKLDNLQKSSFFPAARLSPIVSIQWNPRDIGTVLISYEYVTLTYSLVENEIKQSFIYELPPFAPGGDFSEKTNEKRTPKVIQSLYHPNSLHIITIHEDNSLVFWDANSGHMIMARTVFETEINVPQPDYIRDSSTNAAKISKVYWMCENNPEYTSLLISHKSISRGDNQSLTMIDLGYTPRYSITSYEGMKNYYANPKQMKIFPLPTNVPIVNILPIPRQSPYFAGCHNPGLILLILGNGEIETMLYPSGIFTDKASLFPQNLSWLRPLATTSMAASVPNKLWLGALSAAQNKDYLLKGGVRTKRQKLPAEYGTAFITGHSNGSVRIYDASHGDIQDNASFEVNLSRTLNKAKELAVDKISFAAETLELAVSIETGDVVLFKYEVNQFYSVENRPESGDLEMNFRRFSLNNTNGVLVDVRDRAPTGVRQGFMPSTAVHANKGKTSAINNSNIGFVGIAYAAGSLMLIDRRGPAIIYMENIREISGAQSACVTCIEFVIMEYGDDGYSSILMVCGTDMGEVITYKILPASGGKFDVQLMDITNVTSKGPIHKIDAFSKETKSSCLATIPKMQNLSKGLCIPGIVLITGFDDIRLITLGKSKSTHKGFKYPLAATGLSYISTVEKNNDRKNLTVIITLEINGHLRVFTIPDFKEQMSEHIPFPIAAKYITESSVLRNGDIAIRVSEFQASLFSTVKEQDTLAPVSDTLYINGIRIPYRPQVNSLQWARGTVYCTPAQLNELLGGVNRPASKYKESIIAEGSFSERSSDDNNANHPEHQYTKPTRKGRNSSYGVLRNVSRAVETRWDAVEDRFNDYATAMGETMNEAVEQTGKDVMKGALGF
SIO_010081: YPR032W
subclass of: SO_0000673
so part of: YPR032W
location: 634123..637224
location: region:634123-637224:1
so has part: feature:634123-637224:1:exon

NP_015357.1
type: Protein
SIO_000068: ncbiprotein

S000006236
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:634123-637224:1:exon

YPR033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TS4572
alternative label: TSM4572
gene: HTS1
locus tag: YPR033C
gene synonym: TS4572; TSM4572
so part of: sequence
location: complement(<637379..>639019)
location: region:637379-639019:-1
so has part: feature:637379-639019:-1:exon
subclass of: SO_0000010

856145
type: Gene
SIO_000068: ncbigene

position:637379:-1
position: 637379
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:639019:-1
position: 639019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:637379-639019:-1:exon

YPR033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TS4572
alternative label: TSM4572
gene: HTS1
locus tag: YPR033C
gene synonym: TS4572; TSM4572
product: histidine--tRNA ligase
transcript id: NM_001184130.1
SIO_010081: YPR033C
subclass of: SO_0000673
so part of: YPR033C
location: complement(<637379..>639019)
location: region:637379-639019:-1
so has part: feature:637379-639019:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:637379-639019:-1:exon

YPR033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TS4572
alternative label: TSM4572
gene: HTS1
locus tag: YPR033C
gene synonym: TS4572; TSM4572
EC number: 6.1.1.21
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0004812 aminoacyl-tRNA ligase activity [PMID:16741232]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0006427 histidyl-tRNA aminoacylation [PMID:16741232]
experiment: EXISTENCE:genetic interaction:GO:0032543 mitochondrial translation [PMID:16777356]
experiment: EXISTENCE:mutant phenotype:GO:0005737 cytoplasm [PMID:3521891]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:3521891]
experiment: EXISTENCE:mutant phenotype:GO:0006427 histidyl-tRNA aminoacylation [PMID:1459448]
note: Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome
codon start: 1
product: histidine--tRNA ligase
translation: MLSRSLNKVVTSIKSSSIIRMSSATAAATSAPTANAANALKASKAPKKGKLQVSLKTPKGTKDWADSDMVIREAIFSTLSGLFKKHGGVTIDTPVFELREILAGKYGEDSKLIYNLEDQGGELCSLRYDLTVPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVAGTFESMVPDSECLSILVEGLTSLGIKDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAVDKLDKSPWEAVKKEMTEEKGQSEETADKIGEYVKLNGSLKEIHAVLSADANITSNEKAKQGLDDIATLMKYTEAFDIDSFISFDLSLARGLDYYTGLIYEVVTSASAPPENASELKKKAKSAEDASEFVGVGSIAAGGRYDNLVNMFSEASGKKSTQIPCVGISFGVERIFSLIKQRINSSTTIKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGIEAEYVYKAKANPRKQFDAAEKAGCHIAVILGKEEYLEGKLRVKRLGQEFADDDGELVSAADIVPIVQEKLSQIHEDGLNEVTRLIKGL
SIO_010081: YPR033C
subclass of: SO_0000673
so part of: YPR033C
location: complement(637379..639019)
location: region:637379-639019:-1
so has part: feature:637379-639019:-1:exon

NP_015358.1
type: Protein
SIO_000068: ncbiprotein

S000006237
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:637379-639019:-1:exon

YPR034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RSC11
alternative label: SWP61
gene: ARP7
locus tag: YPR034W
gene synonym: RSC11; SWP61
so part of: sequence
location: <639525..>640958
location: region:639525-640958:1
so has part: feature:639525-640958:1:exon
subclass of: SO_0000010

856146
type: Gene
SIO_000068: ncbigene

position:639525:1
position: 639525
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:640958:1
position: 640958
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:639525-640958:1:exon

YPR034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RSC11
alternative label: SWP61
gene: ARP7
locus tag: YPR034W
gene synonym: RSC11; SWP61
product: Arp7p
transcript id: NM_001184131.1
SIO_010081: YPR034W
subclass of: SO_0000673
so part of: YPR034W
location: <639525..>640958
location: region:639525-640958:1
so has part: feature:639525-640958:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:639525-640958:1:exon

YPR034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RSC11
alternative label: SWP61
gene: ARP7
locus tag: YPR034W
gene synonym: RSC11; SWP61
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11011149]
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:12183366]
experiment: EXISTENCE:direct assay:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:17081996]
experiment: EXISTENCE:direct assay:GO:0016514 SWI/SNF complex [PMID:18644858|PMID:8127913|PMID:9726966]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:10619019|PMID:12183366]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9726966]
note: Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation
codon start: 1
product: Arp7p
translation: MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN
SIO_010081: YPR034W
subclass of: SO_0000673
so part of: YPR034W
location: 639525..640958
location: region:639525-640958:1
so has part: feature:639525-640958:1:exon

NP_015359.1
type: Protein
SIO_000068: ncbiprotein

S000006238
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:639525-640958:1:exon

YPR035W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GLN1
locus tag: YPR035W
so part of: sequence
location: <642208..>643320
location: region:642208-643320:1
so has part: feature:642208-643320:1:exon
subclass of: SO_0000010

856147
type: Gene
SIO_000068: ncbigene

position:642208:1
position: 642208
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:643320:1
position: 643320
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:642208-643320:1:exon

YPR035W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GLN1
locus tag: YPR035W
product: glutamate--ammonia ligase
transcript id: NM_001184132.2
SIO_010081: YPR035W
subclass of: SO_0000673
so part of: YPR035W
location: <642208..>643320
location: region:642208-643320:1
so has part: feature:642208-643320:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:642208-643320:1:exon

YPR035W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GLN1
locus tag: YPR035W
EC number: 6.3.1.2
experiment: EXISTENCE:direct assay:GO:0004356 glutamate-ammonia ligase activity [PMID:4156034]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0006542 glutamine biosynthetic process [PMID:6129248]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:25817432]
experiment: EXISTENCE:mutant phenotype:GO:0004356 glutamate-ammonia ligase activity [PMID:1347768]
note: Glutamine synthetase (GS); synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation; forms filaments of back-to-back stacks of cylindrical homo-decamers at low pH, leading to enzymatic inactivation and storage during states of advanced cellular starvation; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
codon start: 1
product: glutamate--ammonia ligase
translation: MAEASIEKTQILQKYLELDQRGRIIAEYVWIDGTGNLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRGDNIVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLYGSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAIDNADMTKEFERESS
SIO_010081: YPR035W
subclass of: SO_0000673
so part of: YPR035W
location: 642208..643320
location: region:642208-643320:1
so has part: feature:642208-643320:1:exon

NP_015360.2
type: Protein
SIO_000068: ncbiprotein

S000006239
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:642208-643320:1:exon

YPR036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLS11
gene: VMA13
locus tag: YPR036W
gene synonym: CLS11
so part of: sequence
location: <643836..>645272
location: region:643836-645272:1
so has part: feature:643836-645272:1:exon
subclass of: SO_0000010

856148
type: Gene
SIO_000068: ncbigene

position:643836:1
position: 643836
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:645272:1
position: 645272
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:643836-645272:1:exon

YPR036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLS11
gene: VMA13
locus tag: YPR036W
gene synonym: CLS11
product: H(+)-transporting V1 sector ATPase subunit H
transcript id: NM_001184133.1
SIO_010081: YPR036W
subclass of: SO_0000673
so part of: YPR036W
location: <643836..>645272
location: region:643836-645272:1
so has part: feature:643836-645272:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:643836-645272:1:exon

YPR036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLS11
gene: VMA13
locus tag: YPR036W
gene synonym: CLS11
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:23708375|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0007035 vacuolar acidification [PMID:18708638]
note: Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits
codon start: 1
product: H(+)-transporting V1 sector ATPase subunit H
translation: MGATKILMDSTHFNEIRSIIRSRSVAWDALARSEELSEIDASTAKALESILVKKNIGDGLSSSNNAHSGFKVNGKTLIPLIHLLSTSDNEDCKKSVQNLIAELLSSDKYGDDTVKFFQEDPKQLEQLFDVSLKGDFQTVLISGFNVVSLLVQNGLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIPEYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKITIKEKVSRLCISIILQCCSTRVKQHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDNIDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHSDSRVKYEALKATQAIIGYTFK
SIO_010081: YPR036W
subclass of: SO_0000673
so part of: YPR036W
location: 643836..645272
location: region:643836-645272:1
so has part: feature:643836-645272:1:exon

NP_015361.1
type: Protein
SIO_000068: ncbiprotein

S000006240
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:643836-645272:1:exon

YPR036W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPO24
locus tag: YPR036W-A
so part of: sequence
location: <645950..>646153
location: region:645950-646153:1
so has part: feature:645950-646153:1:exon
subclass of: SO_0000010

856149
type: Gene
SIO_000068: ncbigene

position:645950:1
position: 645950
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:646153:1
position: 646153
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:645950-646153:1:exon

YPR036W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPO24
locus tag: YPR036W-A
product: Spo24p
transcript id: NM_001184516.1
SIO_010081: YPR036W-A
subclass of: SO_0000673
so part of: YPR036W-A
location: <645950..>646153
location: region:645950-646153:1
so has part: feature:645950-646153:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:645950-646153:1:exon

YPR036W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPO24
locus tag: YPR036W-A
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:25127041]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:25127041]
note: Small (67 amino acids) protein involved in sporulation; localizes to the prospore membrane; phosphorylated during meiosis; a longer, 5'-extended mRNA is also transcribed beginning in mid-meiosis, regulated by two MSEs (middle sporulation elements), and includes an uORF of 15 codons in its 5'-UTR; evidence transcription is regulated by Pdr1p
codon start: 1
product: Spo24p
translation: MVAFLELTSDVSQPFVIPSLSPVSQPSSRKNSDANVDDLNLAIANAALLDASASSRSHSRKNSLSLL
SIO_010081: YPR036W-A
subclass of: SO_0000673
so part of: YPR036W-A
location: 645950..646153
location: region:645950-646153:1
so has part: feature:645950-646153:1:exon

NP_690847.1
type: Protein
SIO_000068: ncbiprotein

S000028425
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:645950-646153:1:exon

YPR037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERV2
locus tag: YPR037C
so part of: sequence
location: complement(<646448..>647038)
location: region:646448-647038:-1
so has part: feature:646448-647038:-1:exon
subclass of: SO_0000010

856152
type: Gene
SIO_000068: ncbigene

position:646448:-1
position: 646448
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:647038:-1
position: 647038
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:646448-647038:-1:exon

YPR037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERV2
locus tag: YPR037C
product: flavin-linked sulfhydryl oxidase
transcript id: NM_001184134.1
SIO_010081: YPR037C
subclass of: SO_0000673
so part of: YPR037C
location: complement(<646448..>647038)
location: region:646448-647038:-1
so has part: feature:646448-647038:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:646448-647038:-1:exon

YPR037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERV2
locus tag: YPR037C
EC number: 1.8.3.2
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11584268]
experiment: EXISTENCE:direct assay:GO:0016971 flavin-linked sulfhydryl oxidase activity [PMID:11584268]
experiment: EXISTENCE:direct assay:GO:0016972 thiol oxidase activity [PMID:11313344]
experiment: EXISTENCE:direct assay:GO:0060904 regulation of protein folding in endoplasmic reticulum [PMID:11584268]
note: Flavin-linked sulfhydryl oxidase localized to the ER lumen; involved in disulfide bond formation within the endoplasmic reticulum (ER)
codon start: 1
product: flavin-linked sulfhydryl oxidase
translation: MKQIVKRSHAIRIVAALGIIGLWMFFSSNELSIATPGLIKAKSGIDEVQGAAAEKNDARLKEIEKQTIMPLMGDDKVKKEVGRASWKYFHTLLARFPDEPTPEEREKLHTFIGLYAELYPCGECSYHFVKLIEKYPVQTSSRTAAAMWGCHIHNKVNEYLKKDIYDCATILEDYDCGCSDSDGKRVSLEKEAKQHG
SIO_010081: YPR037C
subclass of: SO_0000673
so part of: YPR037C
location: complement(646448..647038)
location: region:646448-647038:-1
so has part: feature:646448-647038:-1:exon

NP_015362.1
type: Protein
SIO_000068: ncbiprotein

S000006241
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:646448-647038:-1:exon

YPR038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC16
locus tag: YPR038W
so part of: sequence
location: <646836..>647195
location: region:646836-647195:1
so has part: feature:646836-647195:1:exon
subclass of: SO_0000010

856150
type: Gene
SIO_000068: ncbigene

position:646836:1
position: 646836
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:647195:1
position: 647195
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:646836-647195:1:exon

YPR038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC16
locus tag: YPR038W
product: Irc16p
transcript id: NM_001395041.1
SIO_010081: YPR038W
subclass of: SO_0000673
so part of: YPR038W
location: <646836..>647195
location: region:646836-647195:1
so has part: feature:646836-647195:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:646836-647195:1:exon

YPR038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC16
locus tag: YPR038W
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:18085829]
note: hypothetical protein; partially overlaps verified gene ERV2/YPR037C but doesn't share phenotypes; also overlaps dubious ORF YPR039W; null mutant displays increased levels of spontaneous Rad52p foci, increased biofilm information, different altered sensitivities to various chemcicals
codon start: 1
product: Irc16p
translation: MVCFSISFNRASFFSAAAPCTSSIPDFALIRPGVAMDSSLDEKNIHRPMIPNAATILMAWLLLTICFIPSFLAQSVQTFLFTNHQPSRLLVFITHVYCLMIKPFVLYFWFLFPLRLPGG
SIO_010081: YPR038W
subclass of: SO_0000673
so part of: YPR038W
location: 646836..647195
location: region:646836-647195:1
so has part: feature:646836-647195:1:exon

NP_001381971.1
type: Protein
SIO_000068: ncbiprotein

S000006242
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:646836-647195:1:exon

YPR040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TIP41
locus tag: YPR040W
so part of: sequence
location: <647305..>648375
location: region:647305-648375:1
so has part: feature:647305-648375:1:exon
subclass of: SO_0000010

856153
type: Gene
SIO_000068: ncbigene

position:647305:1
position: 647305
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:648375:1
position: 648375
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:647305-648375:1:exon

YPR040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TIP41
locus tag: YPR040W
product: Tip41p
transcript id: NM_001184137.1
SIO_010081: YPR040W
subclass of: SO_0000673
so part of: YPR040W
location: <647305..>648375
location: region:647305-648375:1
so has part: feature:647305-648375:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:647305-648375:1:exon

YPR040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TIP41
locus tag: YPR040W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:mutant phenotype:GO:1904262 negative regulation of TORC1 signaling [PMID:11741537]
note: Tap42p-interacting protein; negative regulator of the TORC1 signaling pathway that activates the type 2A-related phosphatase Sit4p by binding and antagonizing Tap42p, a SIT4 inhibitor; proposed to be part of a feedback loop to amplify Sit4p activity when TORC1 is inactivated; protein abundance increases in response to DNA replication stress
codon start: 1
product: Tip41p
translation: MSKRNTPPLRSSGINTIQINAAREMHAQTVRARRMPMPTSGITTPSVQPTAAPATPPRHICNNPNNPQCLHCGSVIIPSPRATLPLEDNPSISINDWTISSRKKPILNSQELDIWENEKLKGLTLPEMIFGNNYIRIENSKQHWSIEFNALDALKEVQLQDSGIRVAYSNDWINSKKRQNSTNGAQRFTNDVNDDSLNIIHKYDWTYTTRYKGTESSPESKFRLDNDQKLPLDKLAVHDKILFYDDMILFEDELADNGISILNVKIRVMNERLLLLSRFFLRVDDVLVRVYDTRIYVEFDENVVIRESKEFEGKYQDVLAKHRLSQSHDPKAALRDSNWVAQNTPMIKRQCEIIQF
SIO_010081: YPR040W
subclass of: SO_0000673
so part of: YPR040W
location: 647305..648375
location: region:647305-648375:1
so has part: feature:647305-648375:1:exon

NP_015365.1
type: Protein
SIO_000068: ncbiprotein

S000006244
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:647305-648375:1:exon

YPR041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SUI5
gene: TIF5
locus tag: YPR041W
gene synonym: SUI5
so part of: sequence
location: <648704..>649921
location: region:648704-649921:1
so has part: feature:648704-649921:1:exon
subclass of: SO_0000010

856154
type: Gene
SIO_000068: ncbigene

position:648704:1
position: 648704
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:649921:1
position: 649921
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:648704-649921:1:exon

YPR041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SUI5
gene: TIF5
locus tag: YPR041W
gene synonym: SUI5
product: translation initiation factor eIF5
transcript id: NM_001184138.1
SIO_010081: YPR041W
subclass of: SO_0000673
so part of: YPR041W
location: <648704..>649921
location: region:648704-649921:1
so has part: feature:648704-649921:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:648704-649921:1:exon

YPR041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SUI5
gene: TIF5
locus tag: YPR041W
gene synonym: SUI5
experiment: EXISTENCE:direct assay:GO:0001732 formation of cytoplasmic translation initiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0003743 translation initiation factor activity [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0005092 GDP-dissociation inhibitor activity [PMID:20485439]
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:9308967]
experiment: EXISTENCE:direct assay:GO:0006446 regulation of translational initiation [PMID:22851688]
experiment: EXISTENCE:direct assay:GO:0031369 translation initiation factor binding [PMID:15145951|PMID:22683627|PMID:16380131]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0043614 multi-eIF complex [PMID:11018020|PMID:15838098]
experiment: EXISTENCE:genetic interaction:GO:0045947 negative regulation of translational initiation [PMID:20485439]
experiment: EXISTENCE:mutant phenotype:GO:0005092 GDP-dissociation inhibitor activity [PMID:20485439]
experiment: EXISTENCE:mutant phenotype:GO:0005096 GTPase activator activity [PMID:9308967]
experiment: EXISTENCE:mutant phenotype:GO:0006446 regulation of translational initiation [PMID:11331597|PMID:22851688]
experiment: EXISTENCE:mutant phenotype:GO:0042256 cytosolic ribosome assembly [PMID:11331597]
experiment: EXISTENCE:mutant phenotype:GO:0045947 negative regulation of translational initiation [PMID:20485439]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:22683627|PMID:9395514]
experiment: EXISTENCE:physical interaction:GO:0031369 translation initiation factor binding [PMID:15145951|PMID:22851688]
note: Translation initiation factor eIF5; functions as both a GTPase-activating protein (GAP) that stimulates the hydrolysis of GTP bound to eIF-2, as part of the 43S preinitiation complex, and as a GDP dissociation inhibitor (GDI) to prevent recycling of eIF2; human ortholog eIF5 complements the yeast null mutant
codon start: 1
product: translation initiation factor eIF5
translation: MSINICRDNHDPFYRYKMPPIQAKVEGRGNGIKTAVLNVADISHALNRPAPYIVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQDVLDGFINKFVLCGSCKNPETEIIITKDNDLVRDCKACGKRTPMDLRHKLSSFILKNPPDSVSGSKKKKKAATASANVRGGGLSISDIAQGKSQNAPSDGTGSSTPQHHDEDEDELSRQIKAAASTLEDIEVKDDEWAVDMSEEAIRARAKELEVNSELTQLDEYGEWILEQAGEDKENLPSDVELYKKAAELDVLNDPKIGCVLAQCLFDEDIVNEIAEHNAFFTKILVTPEYEKNFMGGIERFLGLEHKDLIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWLETAESDDDEEDDE
SIO_010081: YPR041W
subclass of: SO_0000673
so part of: YPR041W
location: 648704..649921
location: region:648704-649921:1
so has part: feature:648704-649921:1:exon

NP_015366.1
type: Protein
SIO_000068: ncbiprotein

S000006245
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:648704-649921:1:exon

YPR042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PUF2
locus tag: YPR042C
so part of: sequence
location: complement(<650435..>653662)
location: region:650435-653662:-1
so has part: feature:650435-653662:-1:exon
subclass of: SO_0000010

856155
type: Gene
SIO_000068: ncbigene

position:650435:-1
position: 650435
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:653662:-1
position: 653662
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:650435-653662:-1:exon

YPR042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PUF2
locus tag: YPR042C
product: Puf2p
transcript id: NM_001184139.1
SIO_010081: YPR042C
subclass of: SO_0000673
so part of: YPR042C
location: complement(<650435..>653662)
location: region:650435-653662:-1
so has part: feature:650435-653662:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:650435-653662:-1:exon

YPR042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PUF2
locus tag: YPR042C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:21685478|PMID:15024427|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11101532]
note: PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication
codon start: 1
product: Puf2p
translation: MDNKRLYNGNLSNIPEVIDPGITIPIYEEDIRNDTRMNTNARSVRVSDKRGRSSSTSPQKIGSYRTRAGRFSDTLTNLLPSISAKLHHSKKSTPVVVVPPTSSTPDSLNSTTYAPRVSSDSFTVATPLSLQSTTTRTRTRNNTVSSQITASSSLTTDVGNATSANIWSANAESNTSSSPLFDYPLATSYFEPLTRFKSTDNYTLPQTAQLNSFLEKNGNPNIWSSAGNSNTDHLNTPIVNRQRSQSQSTTNRVYTDAPYYQQPAQNYQVQVPPRVPKSTSISPVILDDVDPASINWITANQKVPLVNQISALLPTNTISISNVFPLQPTQQHQQNAVNLTSTSLATLCSQYGKVLSARTLRGLNMALVEFSTVESAICALEALQGKELSKVGAPSTVSFARVLPMYEQPLNVNGFNNTPKQPLLQEQLNHGVLNYQLQQSLQQPELQQQPTSFNQPNLTYCNPTQNLSHLQLSSNENEPYPFPLPPPSLSDSKKDILHTISSFKLEYDHLELNHLLQNALKNKGVSDTNYFGPLPEHNSKVPKRKDTFDAPKLRELRKQFDSNSLSTIEMEQLAIVMLDQLPELSSDYLGNTVIQKLFENSSNIIRDIMLRKCNKYLTSMGVHKNGTWVCQKIIKMANTPRQINLVTSGVSDYCTPLFNDQFGNYVIQGILKFGFPWNSFIFESVLSHFWTIVQNRYGSRAVRACLEADSIITQCQLLTITSLIIVLSPYLATDTNGTLLITWLLDTCTLPNKNLILCDKLVNKNLVKLCCHKLGSLTVLKILNLRGGEEEALSKNKIIHAIFDGPISSDSILFQILDEGNYGPTFIYKVLTSRILDNSVRDEAITKIRQLILNSNINLQSRQLLEEVGLSSAGISPKQSSKNHRKQHPQGFHSPGRARGVSVSSVRSSNSRHNSVIQMNNAGPTPALNFNPAPMSEINSYFNNQQVVYSGNQNQNQNGNSNGLDELNSQFDSFRIANGTNLSLPIVNLPNVSNNNNNYNNSGYSSQMNPLSRSVSHNNNNNTNNYNNNDNDNNNNNNNNNNNNNNNNNNNNNSNNSNNNNNNDTSLYRYRSYGY
SIO_010081: YPR042C
subclass of: SO_0000673
so part of: YPR042C
location: complement(650435..653662)
location: region:650435-653662:-1
so has part: feature:650435-653662:-1:exon

NP_015367.1
type: Protein
SIO_000068: ncbiprotein

S000006246
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:650435-653662:-1:exon

YPR043W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL43A
locus tag: YPR043W
so part of: sequence
location: <654166..>654847
location: region:654166-654847:1
so has part: feature:654166-654847:1:exon
subclass of: SO_0000010

856156
type: Gene
SIO_000068: ncbigene

position:654166:1
position: 654166
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:654847:1
position: 654847
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:654166-654847:1:exon

YPR043W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL43A
locus tag: YPR043W
product: ribosomal 60S subunit protein L43A
transcript id: NM_001184140.1
SIO_010081: YPR043W
subclass of: SO_0000673
so part of: YPR043W
location: join(<654166..654167,654571..>654847)
location: region:654166-654847:1
so has part: feature:654166-654167:1:exon
so has part: feature:654571-654847:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:654166-654167:1:exon

position:654167:1
position: 654167
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:654571-654847:1:exon

position:654571:1
position: 654571
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YPR043W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL43A
locus tag: YPR043W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L43A; null mutation confers a dominant lethal phenotype; homologous to mammalian ribosomal protein L37A, no bacterial homolog; RPL43A has a paralog, RPL43B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L43A
translation: MAKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA
SIO_010081: YPR043W
subclass of: SO_0000673
so part of: YPR043W
location: join(654166..654167,654571..654847)
location: region:654166-654847:1
so has part: feature:654166-654167:1:exon
so has part: feature:654571-654847:1:exon

NP_015368.1
type: Protein
SIO_000068: ncbiprotein

S000006247
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:654166-654167:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:654571-654847:1:exon

YPR045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THP3
locus tag: YPR045C
so part of: sequence
location: complement(<655140..>656552)
location: region:655140-656552:-1
so has part: feature:655140-656552:-1:exon
subclass of: SO_0000010

856158
type: Gene
SIO_000068: ncbigene

position:655140:-1
position: 655140
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:656552:-1
position: 656552
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:655140-656552:-1:exon

YPR045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THP3
locus tag: YPR045C
product: Thp3p
transcript id: NM_001184142.1
SIO_010081: YPR045C
subclass of: SO_0000673
so part of: YPR045C
location: complement(<655140..>656552)
location: region:655140-656552:-1
so has part: feature:655140-656552:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:655140-656552:-1:exon

YPR045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THP3
locus tag: YPR045C
experiment: EXISTENCE:direct assay:GO:0000791 euchromatin [PMID:21149575]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:19061648]
note: Protein that may have a role in transcription elongation; forms a complex with Csn12p that is recruited to transcribed genes; possibly involved in splicing based on pre-mRNA accumulation defect for many intron-containing genes
codon start: 1
product: Thp3p
translation: MQNPYGHFTNNTTEDREASSQGGPFGQSLNRPLDYAGSFPSLTYNNNNFIANQQPSLPLPEPRLSWNNVNQVSNPLMVTPLPGLQKRMNKNIKKKLPRVSKKASALSNGVSGNVMSNSNIVGHGAVGSASGWKVEMGGSDELERRKRRAERFSQGPSATTNSNDNLNEDFANLNAISSKSHQYDKKIHVVGRCQTLEKSYLRLTSEPNPDLIRPPNILQKMYCLLMDKYQSKTATYTYLCDQFKSMRQDLRVQMIENSFTIKVYQTHARIALENGDLGEFNQCQNRIMALFENPTIPKKSYSEFICYSVLYSMLTEDYPSISHLKLKLIDDGSSEILEDEHVKMIFELSDMKLVGNYHYFMKNYLKLHKFEKCLINSFLNLEKLIFLTIICKSYNQVNLDFVKSEFNFNSIEETTNFLNEQNLTEFILNKQITDSNGKSSNIKILNTKGCRVQLIQNYMKSKKIDIKGQK
SIO_010081: YPR045C
subclass of: SO_0000673
so part of: YPR045C
location: complement(655140..656552)
location: region:655140-656552:-1
so has part: feature:655140-656552:-1:exon

NP_015370.1
type: Protein
SIO_000068: ncbiprotein

S000006249
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:655140-656552:-1:exon

YPR046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MCM16
locus tag: YPR046W
so part of: sequence
location: <656799..>657344
location: region:656799-657344:1
so has part: feature:656799-657344:1:exon
subclass of: SO_0000010

856159
type: Gene
SIO_000068: ncbigene

position:656799:1
position: 656799
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:657344:1
position: 657344
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:656799-657344:1:exon

YPR046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MCM16
locus tag: YPR046W
product: Mcm16p
transcript id: NM_001184143.1
SIO_010081: YPR046W
subclass of: SO_0000673
so part of: YPR046W
location: <656799..>657344
location: region:656799-657344:1
so has part: feature:656799-657344:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:656799-657344:1:exon

YPR046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MCM16
locus tag: YPR046W
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:11782448]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:11782448]
experiment: EXISTENCE:mutant phenotype:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:19730685]
note: Component of the Ctf19 complex and the COMA subcomplex; involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-H and fission yeast fta3
codon start: 1
product: Mcm16p
translation: MTNSSEKQWERIQQLEKEHVEVYRELLITLDRLYLIRKHNHAVILSHTQQRLLEIRHQLQINLEKTALLIRLLEKPDNTNVLFTKLQNLLEESNSLDYELLQSLGAQSSLHKQLIESRAERDELMSKLIELSSKFPKPTIPPDDSDTAGKQVEVEKENETIQELMIALQIHSGYTNISYTI
SIO_010081: YPR046W
subclass of: SO_0000673
so part of: YPR046W
location: 656799..657344
location: region:656799-657344:1
so has part: feature:656799-657344:1:exon

NP_015371.1
type: Protein
SIO_000068: ncbiprotein

S000006250
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:656799-657344:1:exon

YPR047W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MSF1
locus tag: YPR047W
so part of: sequence
location: <657529..>658938
location: region:657529-658938:1
so has part: feature:657529-658938:1:exon
subclass of: SO_0000010

856160
type: Gene
SIO_000068: ncbigene

position:657529:1
position: 657529
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:658938:1
position: 658938
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:657529-658938:1:exon

YPR047W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MSF1
locus tag: YPR047W
product: phenylalanine--tRNA ligase
transcript id: NM_001184144.1
SIO_010081: YPR047W
subclass of: SO_0000673
so part of: YPR047W
location: <657529..>658938
location: region:657529-658938:1
so has part: feature:657529-658938:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:657529-658938:1:exon

YPR047W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MSF1
locus tag: YPR047W
EC number: 6.1.1.20
experiment: EXISTENCE:direct assay:GO:0004826 phenylalanine-tRNA ligase activity [PMID:16162501]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0004826 phenylalanine-tRNA ligase activity [PMID:3029120]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:3029120]
experiment: EXISTENCE:mutant phenotype:GO:0070156 mitochondrial phenylalanyl-tRNA aminoacylation [PMID:3029120]
note: Mitochondrial phenylalanyl-tRNA synthetase; active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase
codon start: 1
product: phenylalanine--tRNA ligase
translation: MFLNRMMKTRTGLYRLYSTLKVPHVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKLNSVDNTFKIFNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSGFLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVKITVDDDTIPLKENNPKQEYMSDLEVDLCSQHLKRSIELIVSEVFNKKISSMIKNKANNTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYKPSETIGWAFGLGLDRIAMLLFEIPDIRLLWSRDERFSRQFSKGLITSFKPYSKHPGSFRDVAFWLPEDKPDIHQVHENDLMEIIRNIAGDLVESVKLVDSFTHPKTGRKSMCYRINYQSMDRNLTNAEVNTLQDMVCSKLVKEYSVELR
SIO_010081: YPR047W
subclass of: SO_0000673
so part of: YPR047W
location: 657529..658938
location: region:657529-658938:1
so has part: feature:657529-658938:1:exon

NP_015372.2
type: Protein
SIO_000068: ncbiprotein

S000006251
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:657529-658938:1:exon

YPR048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TAH18
locus tag: YPR048W
so part of: sequence
location: <659182..>661053
location: region:659182-661053:1
so has part: feature:659182-661053:1:exon
subclass of: SO_0000010

856161
type: Gene
SIO_000068: ncbigene

position:659182:1
position: 659182
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:661053:1
position: 661053
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:659182-661053:1:exon

YPR048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TAH18
locus tag: YPR048W
product: NAPDH-dependent diflavin reductase
transcript id: NM_001184145.1
SIO_010081: YPR048W
subclass of: SO_0000673
so part of: YPR048W
location: <659182..>661053
location: region:659182-661053:1
so has part: feature:659182-661053:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:659182-661053:1:exon

YPR048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TAH18
locus tag: YPR048W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19194512]
experiment: EXISTENCE:direct assay:GO:0016651 oxidoreductase activity, acting on NAD(P)H [PMID:20802492]
experiment: EXISTENCE:mutant phenotype:GO:0006809 nitric oxide biosynthetic process [PMID:23159617]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:20802492]
experiment: EXISTENCE:mutant phenotype:GO:0045429 positive regulation of nitric oxide biosynthetic process [PMID:27178802]
experiment: EXISTENCE:mutant phenotype:GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death [PMID:27178802]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:27178802]
note: Conserved NAPDH-dependent diflavin reductase; component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress; Tah18p-dependent nitric oxide synthesis confers high-temperature stress tolerance; possible target for development of antifungal drugs
codon start: 1
product: NAPDH-dependent diflavin reductase
translation: MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQGELPRNVNALKGERPVTFWSFLKRKNLPSNLLNHIQTAMLGLGDSSYPKFNYGIRKLHQRIVTQLGANELFDRLEADDQAMAGSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANEKFTSTKVIFEGDESLKVGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQSHWLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDFISVKLPWKYVLDYLPIIKPRYYSISSGPGDPNIELTVAIVKYKTILRKIRRGICTNYIARLQEGEQIRYKLQNNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISKDIKLLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCGSSGKMPIQVRLTFIEMLKKWGNFSDEETAKKYLKEMEKSDRYIQETW
SIO_010081: YPR048W
subclass of: SO_0000673
so part of: YPR048W
location: 659182..661053
location: region:659182-661053:1
so has part: feature:659182-661053:1:exon

NP_015373.1
type: Protein
SIO_000068: ncbiprotein

S000006252
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:659182-661053:1:exon

YPR049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CVT3
alternative label: CVT9
gene: ATG11
locus tag: YPR049C
gene synonym: CVT3; CVT9
so part of: sequence
location: complement(<661137..>664673)
location: region:661137-664673:-1
so has part: feature:661137-664673:-1:exon
subclass of: SO_0000010

856162
type: Gene
SIO_000068: ncbigene

position:661137:-1
position: 661137
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:664673:-1
position: 664673
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:661137-664673:-1:exon

YPR049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CVT3
alternative label: CVT9
gene: ATG11
locus tag: YPR049C
gene synonym: CVT3; CVT9
product: autophagy protein ATG11
transcript id: NM_001184146.1
SIO_010081: YPR049C
subclass of: SO_0000673
so part of: YPR049C
location: complement(<661137..>664673)
location: region:661137-664673:-1
so has part: feature:661137-664673:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:661137-664673:-1:exon

YPR049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CVT3
alternative label: CVT9
gene: ATG11
locus tag: YPR049C
gene synonym: CVT3; CVT9
experiment: EXISTENCE:direct assay:GO:0000045 autophagosome assembly [PMID:18725539]
experiment: EXISTENCE:direct assay:GO:0000149 SNARE binding [PMID:26774783]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:15659643]
experiment: EXISTENCE:direct assay:GO:0006914 autophagy [PMID:28013049]
experiment: EXISTENCE:direct assay:GO:0034497 protein localization to phagophore assembly site [PMID:23858448|PMID:26774783]
experiment: EXISTENCE:direct assay:GO:0140255 regulation of cellular response to phosphate starvation [PMID:28013049]
experiment: EXISTENCE:genetic interaction:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:15659643]
experiment: EXISTENCE:genetic interaction:GO:0060090 molecular adaptor activity [PMID:17295840]
experiment: EXISTENCE:genetic interaction:GO:2000786 positive regulation of autophagosome assembly [PMID:18077553]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:11309418]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:12479808]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:15659643]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:17135291]
experiment: EXISTENCE:mutant phenotype:GO:0034517 ribophagy [PMID:27659307]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0061709 reticulophagy [PMID:26181331]
experiment: EXISTENCE:physical interaction:GO:0034497 protein localization to phagophore assembly site [PMID:23858448]
note: Adapter protein for pexophagy and the Cvt targeting pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the PAS; recruits Dnm1p to facilitate fission of mitochondria that are destined for removal by mitophagy
codon start: 1
product: autophagy protein ATG11
translation: MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTPTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQMFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFQQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEMGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYDDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSYAETNSSSMEKGEKFETIPLAEDPGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV
SIO_010081: YPR049C
subclass of: SO_0000673
so part of: YPR049C
location: complement(661137..664673)
location: region:661137-664673:-1
so has part: feature:661137-664673:-1:exon

NP_015374.1
type: Protein
SIO_000068: ncbiprotein

S000006253
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:661137-664673:-1:exon

YPR051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NAA30
gene: MAK3
locus tag: YPR051W
gene synonym: NAA30
so part of: sequence
location: <664960..>665490
location: region:664960-665490:1
so has part: feature:664960-665490:1:exon
subclass of: SO_0000010

856163
type: Gene
SIO_000068: ncbigene

position:664960:1
position: 664960
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:665490:1
position: 665490
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:664960-665490:1:exon

YPR051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NAA30
gene: MAK3
locus tag: YPR051W
gene synonym: NAA30
product: peptide alpha-N-acetyltransferase MAK3
transcript id: NM_001184148.1
SIO_010081: YPR051W
subclass of: SO_0000673
so part of: YPR051W
location: <664960..>665490
location: region:664960-665490:1
so has part: feature:664960-665490:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:664960-665490:1:exon

YPR051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NAA30
gene: MAK3
locus tag: YPR051W
gene synonym: NAA30
EC number: 2.3.1.256
experiment: EXISTENCE:direct assay:GO:0031417 NatC complex [PMID:10504710]
experiment: EXISTENCE:mutant phenotype:GO:0004596 peptide alpha-N-acetyltransferase activity [PMID:11274203]
experiment: EXISTENCE:mutant phenotype:GO:0006474 N-terminal protein amino acid acetylation [PMID:11274203]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:15077113|PMID:15077114|PMID:15911569|PMID:17261844]
note: Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT); involved in subcellular targeting of select N-terminally acetylated substrates to the Golgi apparatus (Arl3p and Grh1p) and the inner nuclear membrane (Trm1p); required for replication of dsRNA virus; human NatC ortholog, NAA30, functionally complements the null, requiring either auxiliary subunit Mak10p or co-expression of human ortholog, NAA35; NAA60, the human NatF gene, also complements the null allele
codon start: 1
product: peptide alpha-N-acetyltransferase MAK3
translation: MEIVYKPLDIRNEEQFASIKKLIDADLSEPYSIYVYRYFLNQWPELTYIAVDNKSGTPNIPIGCIVCKMDPHRNVRLRGYIGMLAVESTYRGHGIAKKLVEIAIDKMQREHCDEIMLETEVENSAALNLYEGMGFIRMKRMFRYYLNEGDAFKLILPLTEKSCTRSTFLMHGRLAT
SIO_010081: YPR051W
subclass of: SO_0000673
so part of: YPR051W
location: 664960..665490
location: region:664960-665490:1
so has part: feature:664960-665490:1:exon

NP_015376.1
type: Protein
SIO_000068: ncbiprotein

S000006255
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:664960-665490:1:exon

YPR052C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NHP6A
locus tag: YPR052C
so part of: sequence
location: complement(<665693..>665974)
location: region:665693-665974:-1
so has part: feature:665693-665974:-1:exon
subclass of: SO_0000010

856165
type: Gene
SIO_000068: ncbigene

position:665693:-1
position: 665693
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:665974:-1
position: 665974
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:665693-665974:-1:exon

YPR052C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NHP6A
locus tag: YPR052C
product: high-mobility group nucleosome-binding protein
transcript id: NM_001184149.1
SIO_010081: YPR052C
subclass of: SO_0000673
so part of: YPR052C
location: complement(<665693..>665974)
location: region:665693-665974:-1
so has part: feature:665693-665974:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:665693-665974:-1:exon

YPR052C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NHP6A
locus tag: YPR052C
experiment: EXISTENCE:curator inference:GO:0006298 mismatch repair [PMID:19843605]
experiment: EXISTENCE:direct assay:GO:0001195 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III [PMID:16407207]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17878171|PMID:3169249]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:19683499]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:7721780|PMID:9468494]
experiment: EXISTENCE:direct assay:GO:0031491 nucleosome binding [PMID:11432837|PMID:12805231|PMID:12952948]
experiment: EXISTENCE:direct assay:GO:0032407 MutSalpha complex binding [PMID:19843605]
experiment: EXISTENCE:direct assay:GO:0043392 negative regulation of DNA binding [PMID:19843605]
experiment: EXISTENCE:direct assay:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:8946917]
experiment: EXISTENCE:direct assay:GO:0070898 RNA polymerase III preinitiation complex assembly [PMID:11239460|PMID:16407207|PMID:17178828]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:14739928]
experiment: EXISTENCE:genetic interaction:GO:0070898 RNA polymerase III preinitiation complex assembly [PMID:11533232]
note: High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
codon start: 1
product: high-mobility group nucleosome-binding protein
translation: MVTPREPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA
SIO_010081: YPR052C
subclass of: SO_0000673
so part of: YPR052C
location: complement(665693..665974)
location: region:665693-665974:-1
so has part: feature:665693-665974:-1:exon

NP_015377.1
type: Protein
SIO_000068: ncbiprotein

S000006256
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:665693-665974:-1:exon

YPR053C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR053C
so part of: sequence
location: complement(<665788..>666243)
location: region:665788-666243:-1
so has part: feature:665788-666243:-1:exon
subclass of: SO_0000010

856166
type: Gene
SIO_000068: ncbigene

position:665788:-1
position: 665788
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:666243:-1
position: 666243
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:665788-666243:-1:exon

YPR053C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR053C
product: uncharacterized protein
transcript id: NM_001348887.1
SIO_010081: YPR053C
subclass of: SO_0000673
so part of: YPR053C
location: complement(<665788..>666243)
location: region:665788-666243:-1
so has part: feature:665788-666243:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:665788-666243:-1:exon

YPR053C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR053C
note: hypothetical protein; conserved among S. cerevisiae strains; YPR053C is not an essential gene; partially overlaps verified ORF NHP6A/YPR052C
codon start: 1
product: uncharacterized protein
translation: MMYRTTLNTVQVSQISGAEFYPHASSRAILFESPAFCRLFFSPFVYLAVGKQTTQYLLLVPTVKEGLFWDVFFSCFCSIDYPIHSKAQSQWSPQENLRREPLERRRTQMPLRGLCPPTCFSLTKTEILFVLKIQISHLDKSARSWVRSGRL
SIO_010081: YPR053C
subclass of: SO_0000673
so part of: YPR053C
location: complement(665788..666243)
location: region:665788-666243:-1
so has part: feature:665788-666243:-1:exon

NP_001335825.1
type: Protein
SIO_000068: ncbiprotein

S000006257
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:665788-666243:-1:exon

YPR054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMK1
locus tag: YPR054W
so part of: sequence
location: <666280..>667446
location: region:666280-667446:1
so has part: feature:666280-667446:1:exon
subclass of: SO_0000010

856167
type: Gene
SIO_000068: ncbigene

position:666280:1
position: 666280
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:667446:1
position: 667446
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:666280-667446:1:exon

YPR054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMK1
locus tag: YPR054W
product: mitogen-activated protein kinase SMK1
transcript id: NM_001184151.1
SIO_010081: YPR054W
subclass of: SO_0000673
so part of: YPR054W
location: <666280..>667446
location: region:666280-667446:1
so has part: feature:666280-667446:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:666280-667446:1:exon

YPR054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMK1
locus tag: YPR054W
EC number: 2.7.11.24
experiment: EXISTENCE:direct assay:GO:0004707 MAP kinase activity [PMID:16116083]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0070056 prospore membrane leading edge [PMID:33466572]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:16116083]
experiment: EXISTENCE:genetic interaction:GO:0042174 negative regulation of sporulation resulting in formation of a cellular spore [PMID:16116083]
experiment: EXISTENCE:mutant phenotype:GO:0004707 MAP kinase activity [PMID:16116083]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:16116083|PMID:7958885]
note: Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for prospore membrane development and the production of outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p; activated by Cak1p-mediated phosphorylation of threonine (T207) in the activation loop during meiosis I followed by Ssp2p-promoted autophosphorylation of tyrosine (T209) during meiosis II
codon start: 1
product: mitogen-activated protein kinase SMK1
translation: MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL
SIO_010081: YPR054W
subclass of: SO_0000673
so part of: YPR054W
location: 666280..667446
location: region:666280-667446:1
so has part: feature:666280-667446:1:exon

NP_015379.1
type: Protein
SIO_000068: ncbiprotein

S000006258
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:666280-667446:1:exon

YPR055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEC8
locus tag: YPR055W
so part of: sequence
location: <667676..>670873
location: region:667676-670873:1
so has part: feature:667676-670873:1:exon
subclass of: SO_0000010

856168
type: Gene
SIO_000068: ncbigene

position:667676:1
position: 667676
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:670873:1
position: 670873
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:667676-670873:1:exon

YPR055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEC8
locus tag: YPR055W
product: exocyst subunit SEC8
transcript id: NM_001184152.1
SIO_010081: YPR055W
subclass of: SO_0000673
so part of: YPR055W
location: <667676..>670873
location: region:667676-670873:1
so has part: feature:667676-670873:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:667676-670873:1:exon

YPR055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEC8
locus tag: YPR055W
experiment: EXISTENCE:curator inference:GO:0090522 vesicle tethering involved in exocytosis [PMID:8978675]
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:9491896]
experiment: EXISTENCE:direct assay:GO:0000145 exocyst [PMID:1512289|PMID:7615633|PMID:8978675]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:17717527|PMID:7615633|PMID:9491896|PMID:22842922|PMI D:12960429]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12960429|PMID:9491896|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0006893 Golgi to plasma membrane transport [PMID:7026045]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:6996832]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:7026045]
experiment: EXISTENCE:mutant phenotype:GO:0048309 endoplasmic reticulum inheritance [PMID:15596717]
experiment: EXISTENCE:mutant phenotype:GO:0048313 Golgi inheritance [PMID:15596717]
note: Essential 121 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in ER and Golgi inheritance in small buds; relocalizes away from bud neck upon DNA replication stress
codon start: 1
product: exocyst subunit SEC8
translation: MDYLKPAQKGRRRGLSINSLSETQQSAMNSSLDHLQNDLNRINLQWNRILSDNTNPLELALAFLDDTSVGLGHRYEEFNQLKSQIGSHLQDVVNEHSQVFNTNVASYGKAVSSIMQAQEQTLNLKNCLKEANEKITTDKGSLQELNDNNLKYTKMIDVLVNIEELLQIPEKIEENIRKENFHQVQILLERGFILMNNKSLKTVEILKPINQQLELQEHLLFNNLIEEIHDIMYSKSNKTNFTRVTNNDIFKIISISHNGFTSLENYLYNIVNIDIMEHSKTINKNLEQFIHDQSLNKGNIMLQENAATQAPLAPSRNQENEGFNRIGFLLKTINNINKLPVAFNIITERAKEEIHNIIVKSTESIRSKHPSLLKMATSLKNDNHFGLPVQDILSIILRECFWEIFLKLLYAIQCHRAIFEMSNILQPTSSAKPAFKFNKIWGKLLDEIELLLVRYINDPELISSNNGSIKPINGATNNAPTLPKRKNPKIFSLEYNIEDNSSVKDQAFELKALLKDIFPGFSVSSNMDLDSIYVKDESFEQDEPLVPPSVFNMKVILDPFLLFTQSTSTIVPSVLTQNTISSLTFFDDYMNKSFLPKIQMTMDYLFTVEVESNNPYALELSDENHNIFKTALDFQRLFYNLLNVFNTANTFREKISYCILDLLNHFYNYYLGLFNSLIGTSDRHLTRKIITAWLQNGILMDQEQKILNGDETLFHEESIELFKEIPHFYQAGKGLSKSDLFNNLTLDTILQFSASVLWILNWLPGLKKAINIDEVSQEPMLDADRLRSSWTFSESMDLNYSNPSSSPNSLGNLKILLDDKASKKFDETIDGFKTLKFKLITILRFNIRALCIYDIGSFFQNTKIWNMDVGSIELDQNIASLISELRRTESKLKQQLPEKEKNSIFIGLDIVNNYALIKGAKSIKVLNHNGIKKMLRNVNVLQHAYRNLSSEPSKINMNVTMNFYSLCGSSEAELFEYIKDNELPHCSVEDLKTILRLQFSEEMHRQLKRQSTSSTKGSIKPSNKRYTEALEKLSNLEKEQSKEGARTKIGKLKSKLNAVHTANEK
SIO_010081: YPR055W
subclass of: SO_0000673
so part of: YPR055W
location: 667676..670873
location: region:667676-670873:1
so has part: feature:667676-670873:1:exon

NP_015380.1
type: Protein
SIO_000068: ncbiprotein

S000006259
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:667676-670873:1:exon

YPR056W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TFB4
locus tag: YPR056W
so part of: sequence
location: <671126..>672142
location: region:671126-672142:1
so has part: feature:671126-672142:1:exon
subclass of: SO_0000010

856169
type: Gene
SIO_000068: ncbigene

position:671126:1
position: 671126
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:672142:1
position: 672142
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:671126-672142:1:exon

YPR056W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TFB4
locus tag: YPR056W
product: TFIIH/NER complex subunit TFB4
transcript id: NM_001184153.1
SIO_010081: YPR056W
subclass of: SO_0000673
so part of: YPR056W
location: <671126..>672142
location: region:671126-672142:1
so has part: feature:671126-672142:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:671126-672142:1:exon

YPR056W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TFB4
locus tag: YPR056W
experiment: EXISTENCE:curator inference:GO:0016251 RNA polymerase II general transcription initiation factor activity [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0000439 transcription factor TFIIH core complex [PMID:14500720|PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0005675 transcription factor TFIIH holo complex [PMID:19818408|PMID:27381459]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:19450536|PMID:19679665]
experiment: EXISTENCE:mutant phenotype:GO:0006289 nucleotide-excision repair [PMID:10506223]
experiment: EXISTENCE:physical interaction:GO:0000112 nucleotide-excision repair factor 3 complex [PMID:10681587]
note: Subunit of TFIIH complex; involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p
codon start: 1
product: TFIIH/NER complex subunit TFB4
translation: MDAISDPTFKHARSRKQVTEESPSLLTVIIEIAPKLWTTFDEEGNEKGSIIKVLEALIVFLNAHLAFNSANKVAVIAAYSQGIKYLYPESTSALKASESENKTRSDLKIINSDMYRRFRNVDETLVEEIYKLFELEKKQIEQNSQRSTLAGAMSAGLTYVNRISKESVTTSLKSRLLVLTCGSGSSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSKESTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPSLRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIPPGNKCPACDSQFDEHVIAKLKRKPVVPRLKAKKKVTKP
SIO_010081: YPR056W
subclass of: SO_0000673
so part of: YPR056W
location: 671126..672142
location: region:671126-672142:1
so has part: feature:671126-672142:1:exon

NP_015381.1
type: Protein
SIO_000068: ncbiprotein

S000006260
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:671126-672142:1:exon

YPR057W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BRR1
locus tag: YPR057W
so part of: sequence
location: <672471..>673496
location: region:672471-673496:1
so has part: feature:672471-673496:1:exon
subclass of: SO_0000010

856170
type: Gene
SIO_000068: ncbigene

position:672471:1
position: 672471
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:673496:1
position: 673496
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:672471-673496:1:exon

YPR057W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BRR1
locus tag: YPR057W
product: Brr1p
transcript id: NM_001184154.1
SIO_010081: YPR057W
subclass of: SO_0000673
so part of: YPR057W
location: <672471..>673496
location: region:672471-673496:1
so has part: feature:672471-673496:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:672471-673496:1:exon

YPR057W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BRR1
locus tag: YPR057W
experiment: EXISTENCE:direct assay:GO:0017069 snRNA binding [PMID:8861964]
experiment: EXISTENCE:direct assay:GO:0030532 small nuclear ribonucleoprotein complex [PMID:8861964]
experiment: EXISTENCE:mutant phenotype:GO:0000245 spliceosomal complex assembly [PMID:8861964]
note: snRNP protein component of spliceosomal snRNPs; required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed
codon start: 1
product: Brr1p
translation: MKRGESQAPDAIFGQSRAFALSDSSVNPDVIEYLKSVRQEALRTNAISIKNHMNLQKRTRHKSSMYDDEDEGALKRHAISPSLIRLQRNVEIWVRWFNSVKATVLTNAYEFTGYEDETLDLLLLFLKNYLEDMPSKCTTVEKIISVLNQHSFPEKAEEKEENLQIDEEWAKNILVRLEKTKIDSVEDVKKVITEGDKHELVGYNQWFQYLINNEPQHTTFHEKITSKQLWVLIKYMSNTWIKEIHKKGRHYRRLQDWLFYILVHTPERVTAEYTSILRDLGKKCLELIQKKPVEAHENKITLPKEMAELNVEIPAAVENMTITELTVSVIAVNYGQKDLIE
SIO_010081: YPR057W
subclass of: SO_0000673
so part of: YPR057W
location: 672471..673496
location: region:672471-673496:1
so has part: feature:672471-673496:1:exon

NP_015382.1
type: Protein
SIO_000068: ncbiprotein

S000006261
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:672471-673496:1:exon

YPR058W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YMC1
locus tag: YPR058W
so part of: sequence
location: <673751..>674674
location: region:673751-674674:1
so has part: feature:673751-674674:1:exon
subclass of: SO_0000010

856171
type: Gene
SIO_000068: ncbigene

position:673751:1
position: 673751
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:674674:1
position: 674674
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:673751-674674:1:exon

YPR058W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YMC1
locus tag: YPR058W
product: organic acid transporter
transcript id: NM_001184155.1
SIO_010081: YPR058W
subclass of: SO_0000673
so part of: YPR058W
location: <673751..>674674
location: region:673751-674674:1
so has part: feature:673751-674674:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:673751-674674:1:exon

YPR058W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YMC1
locus tag: YPR058W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:23509072]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16140254|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0005342 organic acid transmembrane transporter activity [PMID:16140254]
experiment: EXISTENCE:genetic interaction:GO:0006783 heme biosynthetic process [PMID:26821380]
experiment: EXISTENCE:genetic interaction:GO:0006839 mitochondrial transport [PMID:16140254]
experiment: EXISTENCE:genetic interaction:GO:0015187 glycine transmembrane transporter activity [PMID:26821380]
experiment: EXISTENCE:genetic interaction:GO:1904983 glycine import into mitochondrion [PMID:26821380]
note: Secondary mitochondrial inner membrane glycine transporter; required with HEM25 for the transport of glycine into mitochondria for the initiation of heme biosynthesis; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; localizes to the vacuole in response to H2O2; YMC1 has a paralog, YMC2, that arose from the whole genome duplication
codon start: 1
product: organic acid transporter
translation: MSEEFPSPQLIDDLEEHPQHDNARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTPTTAMEVVRKLLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHHRNADMSSTLSLPQYYACGVTGGIVNSFLASPIEHVRIRLQTQTGSGTNAEFKGPLECIKKLRHNKALLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATFELAMRLLG
SIO_010081: YPR058W
subclass of: SO_0000673
so part of: YPR058W
location: 673751..674674
location: region:673751-674674:1
so has part: feature:673751-674674:1:exon

NP_015383.1
type: Protein
SIO_000068: ncbiprotein

S000006262
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:673751-674674:1:exon

YPR060C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HGS1
alternative label: OSM2
alternative label: TYR7
gene: ARO7
locus tag: YPR060C
gene synonym: HGS1; OSM2; TYR7
so part of: sequence
location: complement(<674861..>675631)
location: region:674861-675631:-1
so has part: feature:674861-675631:-1:exon
subclass of: SO_0000010

856173
type: Gene
SIO_000068: ncbigene

position:674861:-1
position: 674861
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:675631:-1
position: 675631
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:674861-675631:-1:exon

YPR060C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HGS1
alternative label: OSM2
alternative label: TYR7
gene: ARO7
locus tag: YPR060C
gene synonym: HGS1; OSM2; TYR7
product: chorismate mutase ARO7
transcript id: NM_001184157.1
SIO_010081: YPR060C
subclass of: SO_0000673
so part of: YPR060C
location: complement(<674861..>675631)
location: region:674861-675631:-1
so has part: feature:674861-675631:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:674861-675631:-1:exon

YPR060C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HGS1
alternative label: OSM2
alternative label: TYR7
gene: ARO7
locus tag: YPR060C
gene synonym: HGS1; OSM2; TYR7
EC number: 5.4.99.5
experiment: EXISTENCE:direct assay:GO:0004106 chorismate mutase activity [PMID:3027508]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006571 tyrosine biosynthetic process [PMID:3027508]
experiment: EXISTENCE:mutant phenotype:GO:0009094 L-phenylalanine biosynthetic process [PMID:3027508]
note: Chorismate mutase; catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis
codon start: 1
product: chorismate mutase ARO7
translation: MDFTKPETVLNLQNIRDELVRMEDSIIFKFIERSHFATCPSVYEANHPGLEIPNFKGSFLDWALSNLEIAHSRIRRFESPDETPFFPDKIQKSFLPSINYPQILAPYAPEVNYNDKIKKVYIEKIIPLISKRDGDDKNNFGSVATRDIECLQSLSRRIHFGKFVAEAKFQSDIPLYTKLIKSKDVEGIMKNITNSAVEEKILERLTKKAEVYGVDPTNESGERRITPEYLVKIYKEIVIPITKEVEVEYLLRRLEE
SIO_010081: YPR060C
subclass of: SO_0000673
so part of: YPR060C
location: complement(674861..675631)
location: region:674861-675631:-1
so has part: feature:674861-675631:-1:exon

NP_015385.1
type: Protein
SIO_000068: ncbiprotein

S000006264
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:674861-675631:-1:exon

YPR061C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: JID1
locus tag: YPR061C
so part of: sequence
location: complement(<675977..>676882)
location: region:675977-676882:-1
so has part: feature:675977-676882:-1:exon
subclass of: SO_0000010

856174
type: Gene
SIO_000068: ncbigene

position:675977:-1
position: 675977
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:676882:-1
position: 676882
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:675977-676882:-1:exon

YPR061C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: JID1
locus tag: YPR061C
product: Jid1p
transcript id: NM_001184158.1
SIO_010081: YPR061C
subclass of: SO_0000673
so part of: YPR061C
location: complement(<675977..>676882)
location: region:675977-676882:-1
so has part: feature:675977-676882:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:675977-676882:-1:exon

YPR061C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: JID1
locus tag: YPR061C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:17054397|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:19682992]
note: Probable Hsp40p co-chaperone; has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae
codon start: 1
product: Jid1p
translation: MLHHKFVYPFLFKWHLSCVEKCPPQITFIAKYATANDKNGNRKLTIRDEQWPELADPTPYDIFGIPKAGSGNPKLDKKSLKKKYHRYVKLYHPDHSDNIQIFSSEKVTNSDSKSPLLLTSSEKLHRFKVISQAYDILCDPKKKIVYDTTRQGWTTSYSPRSNVNTENYQYAGSYGYHSNAQYEYWNAGTWEDANSMKNERIQENINPWTVIGIICGLAICIEGTALLAKIQESLSKAEFTHDESGLHLIQSYTNYGLDTDKFSRLRRFLWFRTWGLYKSKEDLDREAKINEEMIRKLKAAK
SIO_010081: YPR061C
subclass of: SO_0000673
so part of: YPR061C
location: complement(675977..676882)
location: region:675977-676882:-1
so has part: feature:675977-676882:-1:exon

NP_015386.1
type: Protein
SIO_000068: ncbiprotein

S000006265
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:675977-676882:-1:exon

YPR062W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FCY1
locus tag: YPR062W
so part of: sequence
location: <677165..>677641
location: region:677165-677641:1
so has part: feature:677165-677641:1:exon
subclass of: SO_0000010

856175
type: Gene
SIO_000068: ncbigene

position:677165:1
position: 677165
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:677641:1
position: 677641
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:677165-677641:1:exon

YPR062W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FCY1
locus tag: YPR062W
product: cytosine deaminase
transcript id: NM_001184159.1
SIO_010081: YPR062W
subclass of: SO_0000673
so part of: YPR062W
location: <677165..>677641
location: region:677165-677641:1
so has part: feature:677165-677641:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:677165-677641:1:exon

YPR062W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FCY1
locus tag: YPR062W
EC number: 3.5.4.1
experiment: EXISTENCE:direct assay:GO:0004131 cytosine deaminase activity [PMID:15535715|PMID:9000374]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0008655 pyrimidine-containing compound salvage [PMID:9000374]
experiment: EXISTENCE:mutant phenotype:GO:0019858 cytosine metabolic process [PMID:9000374]
experiment: EXISTENCE:mutant phenotype:GO:0046087 cytidine metabolic process [PMID:10501935]
note: Cytosine deaminase; zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)
codon start: 1
product: cytosine deaminase
translation: MVTGGMASKWDQKGMDIAYEEAALGYKEGGVPIGGCLINNKDGSVLGRGHNMRFQKGSATLHGEISTLENCGRLEGKVYKDTTLYTTLSPCDMCTGAIIMYGIPRCVVGENVNFKSKGEKYLQTRGHEVVVVDDERCKKIMKQFIDERPQDWFEDIGE
SIO_010081: YPR062W
subclass of: SO_0000673
so part of: YPR062W
location: 677165..677641
location: region:677165-677641:1
so has part: feature:677165-677641:1:exon

NP_015387.1
type: Protein
SIO_000068: ncbiprotein

S000006266
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:677165-677641:1:exon

YPR063C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR063C
so part of: sequence
location: complement(<677812..>678320)
location: region:677812-678320:-1
so has part: feature:677812-678320:-1:exon
subclass of: SO_0000010

856176
type: Gene
SIO_000068: ncbigene

position:677812:-1
position: 677812
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:678320:-1
position: 678320
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:677812-678320:-1:exon

YPR063C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR063C
product: uncharacterized protein
transcript id: NM_001184160.1
SIO_010081: YPR063C
subclass of: SO_0000673
so part of: YPR063C
location: complement(join(<677812..678193,678280..>678320))
location: region:677812-678320:-1
so has part: feature:678280-678320:-1:exon
so has part: feature:677812-678193:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:678280-678320:-1:exon

position:678280:-1
position: 678280
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:677812-678193:-1:exon

position:678193:-1
position: 678193
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YPR063C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR063C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
note: ER-localized hypothetical protein
codon start: 1
product: uncharacterized protein
translation: MTLNNVARPDLCVSYKKIAPPKGLYSATPSISGVVNQSMPMAAIFLRNKFIAWFSLIQSVHYYLNTDEDIIVAYKENKAPSPMDQPPAIKLFMSLIGLCVCYMNLVFPQQIAQPSSSGSKGNTETTIETTTEVETETAKQ
SIO_010081: YPR063C
subclass of: SO_0000673
so part of: YPR063C
location: complement(join(677812..678193,678280..678320))
location: region:677812-678320:-1
so has part: feature:678280-678320:-1:exon
so has part: feature:677812-678193:-1:exon

NP_015388.1
type: Protein
SIO_000068: ncbiprotein

S000006267
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:678280-678320:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:677812-678193:-1:exon

YPR064W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YPR064W
so part of: sequence
location: <678951..>679370
location: region:678951-679370:1
so has part: feature:678951-679370:1:exon
subclass of: SO_0000010

856177
type: Gene
SIO_000068: ncbigene

position:678951:1
position: 678951
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:679370:1
position: 679370
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:678951-679370:1:exon

YPR064W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YPR064W
product: uncharacterized protein
transcript id: NM_001348888.1
SIO_010081: YPR064W
subclass of: SO_0000673
so part of: YPR064W
location: <678951..>679370
location: region:678951-679370:1
so has part: feature:678951-679370:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:678951-679370:1:exon

YPR064W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YPR064W
note: hypothetical protein; conserved among S. cerevisiae strains; YPR064W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MKSCVLSNYVEGLEIIVCGYRNRLLFPFRATQVQAYFKVFSFFFFLLLTLGAAAAAKPTSERQVIFGSADKSPGYHWPVEVSAAWNYRELLCKTIGNLVGKPCSRTWRLLTKKKRAYCCCLFCCSSSYCLAGVLCVFCV
SIO_010081: YPR064W
subclass of: SO_0000673
so part of: YPR064W
location: 678951..679370
location: region:678951-679370:1
so has part: feature:678951-679370:1:exon

NP_001335826.1
type: Protein
SIO_000068: ncbiprotein

S000006268
type: SGD
SIO_000068: sgd